Hub : Genes

SNX25

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1170	0.0390	2.1e-03	0.044	0.015	0.031	0.018	0.030	4.4e-06	5.5e-03	9.9e-05	2.7e-03	1.3e-04
2	GTEx	Cells EBV-transformed lymphocytes	0.3640	0.1020	1.9e-03	0.079	NA	0.030	NA	0.019	1.5e-03	NA	3.6e-02	NA	7.8e-02
3	GTEx	Heart Atrial Appendage	0.2890	0.0920	5.6e-03	0.013	NA	0.007	NA	0.024	7.9e-02	NA	1.4e-01	NA	2.9e-02
4	NTR	Blood	0.0485	0.0125	1.3e-07	0.029	0.024	0.021	0.027	0.029	7.2e-10	2.2e-08	2.0e-07	3.8e-09	7.2e-10
5	TCGA	Cervical Squamous Cell Carcinoma	0.1090	0.0530	3.7e-04	0.032	0.048	0.055	NA	0.038	1.0e-02	2.0e-03	1.1e-03	NA	5.9e-03
6	TCGA	Brain Lower Grade Glioma	0.0196	0.0112	5.1e-03	0.022	0.022	0.005	NA	0.010	1.2e-03	1.3e-03	7.8e-02	NA	2.1e-02
7	TCGA	Prostate Adenocarcinoma	0.0426	0.0221	2.7e-04	0.014	0.029	0.014	NA	0.012	1.2e-02	5.0e-04	1.2e-02	NA	1.9e-02
8	TCGA	Thyroid Carcinoma	0.2080	0.0560	0.0e+00	0.265	0.296	0.317	NA	0.315	9.0e-26	3.6e-29	2.0e-31	NA	2.8e-31

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.2	0.4	1.5	-0.5	-0.6	1.2	-0.2	-0.7	-0.2	-0.4	0.0
Bipolar Disorder or Schizophrenia	0.4	1.1	3.3	0.4	-0.2	0.2	-1.1	-1.8	-1.2	-1.3	0.8
Depressed Affect (Nagel 2018)	0.3	0.7	1.6	0.4	-0.3	0.4	0.8	1.0	1.0	1.3	-0.9
Depression (Nagel 2018)	0.1	0.1	0.3	0.4	0.4	0.1	-0.5	0.5	-0.1	0.5	0.1
Intelligence (Savage-Jansen 2018)	1.0	3.1	6.0	0.3	-2.3	0.6	1.7	1.1	2.2	2.1	-2.5
Neuroticism (Nagel 2018)	1.2	2.8	5.7	1.4	-0.3	-0.9	2.1	1.1	1.7	2.4	-2.3
Schizophrenia (2018)	0.7	1.4	3.0	0.9	0.3	-0.8	-1.3	-1.7	-1.4	-1.4	1.0
Schizophrenia vs Biploar Disorder	0.2	0.2	1.1	-0.0	0.1	0.0	0.1	-0.5	-0.4	-1.0	0.5
Worry (Nagel 2018)	1.4	3.0	6.0	0.9	-0.7	-1.6	2.5	1.3	2.0	2.1	-2.0
Alzheimer’s Disease (in mother)	0.3	0.4	1.5	1.2	0.5	0.5	-0.1	0.7	-0.0	-0.2	0.8
Alzheimer’s Disease (in father)	2.0	2.1	4.6	1.6	-0.6	0.3	1.5	1.3	1.5	2.1	-1.9
Alzheimer’s Disease (including proxy)	0.8	1.2	6.0	2.4	0.7	-0.6	0.7	0.9	0.3	1.0	-0.2
Crohns Disease (2017)	0.4	0.8	2.5	0.4	-1.6	0.1	0.2	-0.4	0.6	0.8	-1.6
Irritable Bowel Disease (IBD)	0.3	0.8	1.9	1.2	-0.5	-0.4	0.1	0.3	0.8	1.4	-1.3
Ulcerative Colitis (UC)	0.4	0.7	2.0	1.4	1.0	-0.3	0.2	0.6	0.5	1.3	-0.5
Major Depression (MDD)	2.2	2.7	4.7	0.9	1.1	-2.2	-1.9	-0.7	-1.7	-2.0	1.8
Reaction Time	0.9	1.6	3.2	1.0	-1.8	0.6	1.0	1.5	1.6	1.1	-1.1
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.8	-0.4	-0.9	0.4	-0.7	0.3	0.1	-0.1	0.0
Breast Cancer	0.3	0.8	3.7	-0.2	-0.1	1.9	-0.5	0.2	-0.3	-0.8	1.1
Ovarian Cancer	0.7	0.9	3.3	-0.3	0.3	0.4	-0.9	-0.0	-0.5	-1.5	1.8
Prostate Cancer	0.3	0.5	2.3	-1.5	-0.1	-0.9	0.1	0.1	-0.1	-0.6	0.4
Age at First Birth	0.7	1.0	5.8	-2.4	-0.4	-1.0	0.7	-0.0	0.5	0.0	-0.5
Bipolar Disorder (2011)	0.3	0.3	0.7	0.5	0.7	-0.9	-0.3	-0.3	-0.3	-0.4	0.3
Body Mass Index (BMI) (2010)	0.4	0.5	0.8	0.7	-0.5	-0.9	0.9	0.5	0.5	0.8	-0.8
Coronary Artery Disease (CAD)	3.5	4.1	9.3	-2.8	-0.3	0.9	-3.1	-0.5	-1.8	-2.6	2.1
Crohns Disease (2012)	1.2	1.9	3.7	-0.8	-1.6	-0.6	0.8	1.9	1.8	1.3	-1.5
Mean Putamen Volume	0.2	0.2	1.1	-0.2	1.0	-0.2	-0.3	0.6	-0.2	0.2	0.2
Fasting Glucose	1.5	1.8	3.1	-1.3	-1.4	0.0	1.4	1.2	1.5	1.3	-1.8
HbA1C	0.1	0.1	0.4	0.5	0.1	-0.0	0.0	0.3	0.1	0.6	-0.7
HDL Cholesterol	0.4	0.6	1.8	0.6	-1.3	1.4	-0.1	0.8	0.6	0.2	-0.4
LDL Cholesterol	0.1	0.2	0.7	-0.6	0.8	0.3	-0.3	-0.6	-0.5	-0.1	0.3
Lupus	0.1	0.2	0.7	-0.1	0.3	0.3	-0.3	0.8	0.2	0.0	0.6
Neuroticism (2016)	1.3	1.9	4.3	2.1	0.7	-0.9	0.9	1.5	1.2	2.0	-1.2
Primary Biliary Cirrhosis	0.4	0.5	1.7	0.9	1.3	0.7	-0.2	-0.1	-0.7	-0.4	0.8
Rheumatoid Arthritis	0.4	0.6	1.5	0.8	-0.9	-1.2	-0.3	-0.8	-0.5	-0.3	0.5
Schizophrenia (2014)	1.6	3.6	8.2	-0.5	0.1	0.1	-1.9	-2.8	-2.2	-2.9	2.0
Triglycerides	0.4	0.6	1.2	-0.5	-0.6	-1.1	0.8	0.8	0.8	0.9	-0.8
Type 2 Diabetes (T2D) (2012)	0.1	0.2	1.0	0.1	0.3	0.4	0.1	-1.0	-0.2	-0.2	0.1
Ulcerative Colitis	0.6	0.8	2.1	1.4	0.7	0.5	0.5	0.6	0.5	1.4	-0.9
Blood Eosinophil Count	0.4	3.2	5.7	2.0	-1.2	0.4	1.9	1.4	1.9	2.3	-2.4
Blood Platelet Count	0.1	0.8	2.5	-0.9	-1.0	1.6	0.1	1.1	0.7	0.3	-0.7
Blood Red Count	0.1	1.4	2.8	-0.8	1.6	0.3	-1.6	-1.1	-1.7	-0.6	1.0
Blood White Count	0.1	0.6	2.1	-1.0	-1.4	0.5	0.7	-0.4	0.6	-0.4	-0.7
Heel T-Score	0.3	2.3	4.0	0.8	0.8	-1.2	-1.8	-1.8	-2.0	-1.9	1.1
BMI	0.2	1.1	7.7	0.3	-2.8	-0.3	0.2	-0.0	0.7	-0.2	-0.7
Height	0.2	3.5	9.5	0.0	3.1	0.6	-2.3	-0.7	-2.4	-0.9	2.4
Waist Hip Ratio (WHR)	0.3	1.1	2.6	-1.5	-1.6	-0.7	0.3	0.6	1.3	0.8	-1.1
Systolic Blood Pressure	0.4	2.1	4.6	1.1	2.1	-0.3	-1.6	-0.7	-1.7	-1.0	2.0
Smoking Status	0.4	0.9	2.1	-0.9	-1.5	-0.5	0.7	0.3	1.1	0.9	-1.2
Allergy or Eczema	0.4	1.1	4.2	1.8	-0.1	-2.0	0.5	0.6	0.2	0.4	-0.5
Cardiovascular Disease	0.1	0.3	0.9	0.6	-0.9	-0.4	0.0	-0.1	-0.1	-0.4	0.8
Hypothyroidism (self reported)	0.1	0.2	0.7	0.7	0.8	0.5	0.1	-0.1	-0.0	0.6	-0.3
Respiratory disease	0.4	0.8	3.4	1.8	-0.7	-0.2	1.0	0.5	0.6	0.5	-0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.9	0.3	-0.4	-1.4	-0.2	-1.1	-0.5	0.2	-0.5
Lung FEV1/FVC ratio	0.2	0.9	5.0	-0.4	-1.1	-2.2	-0.5	-0.5	0.0	-0.0	-0.9
Lung FVC	0.1	0.4	1.1	0.5	0.8	0.0	-0.4	0.2	-0.8	-0.3	1.1
Neuroticism	0.4	0.9	2.6	1.6	0.9	-1.0	0.4	0.6	0.4	1.3	-0.6
Chronotype (morning person)	0.1	0.1	0.5	-0.1	0.7	0.6	0.0	0.2	0.2	0.3	-0.1
Hair Pigment	0.5	14.1	33.8	0.9	-2.2	0.9	5.8	3.6	5.0	4.2	-4.2
Tanning	0.1	0.8	2.2	1.5	0.9	-0.2	-0.7	-1.0	-1.1	-0.1	0.2
Hand grip strength (left)	0.2	0.5	1.8	-1.4	-0.6	-0.3	-0.6	-0.5	-0.0	-0.8	0.3
Number of treatments/medications taken	0.8	1.5	4.3	-0.6	1.4	0.4	-0.9	-0.6	-1.6	-1.2	2.1
Average weekly spirits intake	0.7	0.9	3.0	1.0	1.6	1.7	0.0	0.4	-0.3	0.5	0.0
Sensitivity / hurt feelings	0.5	0.9	2.3	0.1	-0.9	-0.5	0.9	0.3	1.3	1.2	-1.5
Frequency of depressed mood in last 2 weeks	0.9	1.3	4.7	1.5	2.2	0.3	-1.1	-0.1	-1.2	0.3	0.8
Hearing difficulty/problems: Yes	0.7	1.1	2.2	-0.2	-1.5	-1.0	-1.2	-0.6	-0.5	-1.4	1.2
Relative age of first facial hair	0.4	0.8	3.3	0.3	-1.8	-0.2	0.6	-0.4	0.8	0.4	-1.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	5.5	-0.4	1.5	-2.4	-0.6	0.4	-0.6	0.1	0.5
Ever used hormone-replacement therapy (HRT)	1.2	1.6	2.9	-0.8	0.1	1.7	-1.6	0.1	-0.8	-1.7	1.7
Ever had hysterectomy (womb removed)	2.7	3.1	4.7	-1.6	1.6	0.2	-1.9	-1.9	-2.2	-1.9	1.9
Systolic blood pressure, automated reading	0.0	0.1	0.3	0.0	0.1	0.5	0.5	0.3	0.4	0.2	0.0
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	5.6	0.3	-0.4	-2.4	-0.1	1.0	0.3	0.7	-0.2
Angina	0.2	0.2	0.8	-0.1	-0.3	0.3	-0.7	-0.2	-0.3	-0.9	0.2
Medication for hormone replacement therapy	3.4	3.8	8.4	-2.1	1.0	0.8	-2.3	-0.7	-1.6	-2.7	2.9
Vitamin and mineral supplements	0.5	0.6	3.1	-0.2	-0.2	1.8	-0.3	1.2	0.4	0.1	-0.2
Supplements: Zinc	0.6	0.7	2.0	0.1	1.4	0.8	0.6	-0.7	-0.2	1.1	-0.6
Medication: Co-codamol	0.5	0.5	2.0	-0.0	-0.2	-1.3	0.0	-1.4	-0.1	-0.6	0.2
Medication: Metformin	1.1	1.5	4.0	0.8	0.1	-1.0	-1.0	-2.0	-1.6	-1.4	1.0
Diabetes (father)	2.1	2.6	5.6	2.2	1.0	-2.4	-1.5	-0.2	-1.0	-1.5	2.0
Diabetes (mother)	1.1	1.4	4.2	0.5	0.9	0.1	-1.3	-0.5	-1.2	-1.6	2.0
Severe depression (siblings)	6.5	7.3	12.7	0.9	3.1	-1.1	-2.7	-2.7	-3.6	-2.6	3.5
Pack years adult smoking proportion	1.7	2.5	5.7	-0.4	0.5	-0.4	-2.1	-1.5	-1.8	-2.4	2.0
Impedance of leg (right)	0.5	2.6	6.1	0.6	1.7	0.5	1.9	1.9	1.6	2.5	-1.3
Leg fat-free mass (left)	0.6	3.1	6.6	-1.2	-1.4	-0.7	-2.4	-1.8	-1.7	-2.6	1.5
Trunk fat percentage	0.3	1.2	3.2	1.8	-0.5	-0.9	-0.7	-1.6	-0.9	-1.1	0.4
Hand grip strength (right)	0.1	0.1	0.4	-0.2	-0.6	-0.3	0.1	-0.6	0.2	-0.3	-0.3
Townsend deprivation index at recruitment	1.0	1.3	2.4	0.6	1.1	-1.1	-1.0	-1.1	-1.5	-1.1	1.4
Current tobacco smoking	0.4	0.7	2.2	-1.5	-0.8	-0.6	-0.7	-0.4	-0.4	-1.0	0.2
Average weekly fortified wine intake	0.6	0.7	2.0	-0.4	1.3	-1.4	0.4	0.6	-0.3	0.0	1.1
Maternal smoking around birth	0.4	0.6	1.3	-0.8	-0.4	0.8	-0.5	-1.2	-0.7	-1.0	0.2
Fed-up feelings	0.4	0.7	2.1	0.2	-1.0	-1.4	0.5	0.7	0.8	0.6	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	0.3	0.7	-0.9	-0.5	0.4	-0.2	1.0	-0.3
Relative age voice broke	0.4	0.5	1.8	0.2	-1.3	-0.1	1.1	-0.9	0.4	-0.2	-0.6
Taking other prescription medications	0.9	1.4	2.8	-0.5	1.5	-0.1	-0.6	-1.4	-1.7	-1.4	1.4
Age when periods started (menarche)	0.5	1.1	3.7	0.0	0.5	0.6	1.9	1.0	1.0	1.3	-1.0
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	4.0	-2.0	1.5	-0.2	-1.7	-1.6	-1.7	-1.5	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.9	1.9	5.6	-0.2	1.2	0.3	-2.4	0.6	-1.4	-1.5	1.9
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.5	-0.9	-0.7	1.7	1.6	0.1	1.1	1.0	-1.9
Qualifications: CSEs or equivalent	0.6	0.8	2.4	1.1	-0.2	0.2	1.6	0.2	0.6	1.2	-0.8
Serious illness, injury or assault to yourself	1.1	1.4	4.0	1.4	-1.2	-2.0	1.1	-0.9	0.7	0.5	-1.0
High blood pressure	1.1	3.1	8.0	0.2	0.1	-0.4	-1.8	-1.6	-2.1	-2.5	2.8
Hayfever, allergic rhinitis or eczema	0.7	1.4	5.8	2.4	0.9	-2.1	-0.1	0.5	-0.3	0.2	0.1
Multivitamins +/- minerals	0.5	0.7	1.2	-1.1	0.1	-0.3	-0.2	-1.1	-1.0	-0.8	1.0
Stomach or abdominal pain in last month	0.4	0.5	2.8	-0.3	0.2	-1.7	0.5	0.5	0.3	0.6	-0.0
Supplements: Glucosamine	1.0	1.3	3.6	-0.7	0.5	1.9	-0.9	-1.3	-0.9	-1.2	1.2
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	2.0	0.5	0.2	-1.4	0.6	0.4	0.1	0.7	-0.1
Medication: Atenolol	2.4	3.0	6.6	-2.6	0.7	-0.4	-2.2	-0.4	-1.3	-2.1	2.3
Medication: Levothyroxine sodium	0.1	0.1	0.7	0.1	0.2	0.1	-0.8	-0.2	-0.2	-0.1	0.5
Sitting height	0.3	2.5	5.5	-1.0	2.2	-0.4	-2.3	0.3	-1.8	-1.1	1.9
Chronic bronchitis/emphysema (father)	0.3	0.4	1.3	-0.3	0.1	0.0	-0.2	-1.1	-0.7	-0.8	0.8
High blood pressure (mother)	0.5	0.7	2.0	-0.4	1.0	0.1	-0.6	-0.2	-0.9	-0.9	1.4
Body mass index (BMI)	0.3	1.1	4.9	0.8	-2.2	-0.8	-0.4	-1.2	-0.2	-0.9	-0.2
Impedance of leg (left)	0.4	1.9	5.0	0.7	2.2	0.5	1.4	1.5	1.0	1.9	-0.6
Leg predicted mass (left)	0.6	3.0	6.3	-1.1	-1.4	-0.7	-2.3	-1.8	-1.7	-2.5	1.4
Trunk fat mass	0.3	1.4	2.7	1.0	-0.8	-0.9	-1.2	-1.6	-1.2	-1.5	0.8
Waist circumference	0.3	1.0	4.9	0.6	-2.2	-1.0	-0.6	-0.8	0.0	-0.8	-0.2
Number of incorrect matches in round	1.5	2.4	4.2	-0.6	0.9	1.8	-1.5	-1.5	-1.8	-1.8	2.0
Past tobacco smoking	0.7	1.2	2.1	0.4	1.2	-0.7	-1.4	-0.4	-1.4	-1.3	1.4
Alcohol usually taken with meals	0.5	0.8	2.2	0.5	1.3	-0.5	0.5	1.5	0.3	1.2	0.2
Nervous feelings	1.4	2.6	4.8	1.1	-1.6	-0.2	1.9	1.3	2.2	1.8	-2.0
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	6.2	2.5	0.1	-0.9	1.4	0.9	1.0	2.0	-1.7
Hearing difficulty/problems with background noise	0.5	0.8	2.1	-0.7	-0.3	-0.5	-1.4	-0.3	-0.9	-1.2	1.2
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	0.1	-0.8	0.2	1.5	-0.4	1.1	1.2	-1.4
Had menopause	0.9	1.1	3.7	-0.3	1.0	-0.3	-0.6	-1.9	-1.1	-1.2	0.9
Had other major operations	0.6	0.7	2.4	-0.1	1.5	-1.2	0.4	-1.2	-0.7	0.1	-0.2
Forced vital capacity (FVC)	0.2	0.8	3.6	0.3	1.9	-0.4	-0.7	0.3	-0.8	-0.2	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	6.8	-0.2	0.9	-0.7	-2.6	1.0	-1.4	-1.3	1.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.0	-0.6	-0.1	-1.4	1.0	-0.0	0.4	0.6	-0.8
Qualifications: None of the above	1.3	2.7	6.5	-1.2	0.5	-1.6	-2.5	-0.8	-1.6	-2.1	1.8
Financial difficulties in last 2 years	0.5	0.7	2.2	1.3	-0.7	0.1	0.2	-1.5	-0.4	-0.9	-0.1
Mouth/teeth dental problems	0.2	0.2	1.0	-1.0	-0.7	0.3	0.2	-0.2	0.1	-0.5	0.0
Heart attack	1.5	1.9	4.3	-0.3	1.1	-0.2	-1.4	-1.8	-2.1	-1.6	1.4
Allergy	0.7	1.6	5.5	-2.3	0.2	1.7	-0.8	-1.2	-0.7	-1.0	0.8
Pain all over the body in last month	0.5	0.5	3.3	1.8	0.1	0.7	-0.2	0.4	0.1	0.6	-0.1
Diabetes (self-reported)	0.4	0.6	1.2	0.7	0.5	-0.8	-1.0	-0.6	-1.1	-0.4	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.8	0.9	-0.2	0.4	0.5	-0.5	-0.3	0.1	-0.1
Medication: Ramipril	1.0	1.3	3.4	0.9	0.7	-1.8	-0.7	-0.3	-1.2	-0.9	1.7
Medication: Simvastatin	0.2	0.2	0.8	0.6	-0.4	0.0	-0.9	-0.5	-0.2	-0.3	0.3
Fluid intelligence score	0.4	0.8	3.0	1.1	-0.6	1.7	0.3	1.0	0.7	0.7	-0.6
Illnesses of siblings	0.2	0.2	1.0	-0.2	-1.0	-0.0	0.1	0.2	0.5	0.3	-0.5
Neuroticism score	0.4	0.8	1.9	1.1	1.1	-0.6	0.7	0.7	0.5	1.4	-1.0
Weight	0.2	1.1	2.0	-0.1	-1.3	-0.7	-1.4	-1.2	-0.9	-1.4	0.7
Impedance of arm (right)	0.5	2.2	12.6	1.7	3.5	0.2	0.7	0.1	-0.7	0.4	0.7
Arm fat percentage (right)	0.2	0.8	2.5	1.6	-0.9	-1.2	-0.2	-1.0	-0.4	-0.7	0.1
Trunk fat-free mass	0.4	2.1	5.7	-2.4	-1.2	-0.3	-2.0	-0.5	-0.9	-1.6	1.2
Hip circumference	0.1	0.6	1.9	1.4	-1.1	-0.7	-0.4	-0.6	-0.3	-0.7	0.3
Time employed in main current job	3.1	3.6	8.2	-0.6	1.5	-0.3	-2.9	-1.0	-2.1	-2.3	2.6
Alcohol intake versus 10 years previously	0.4	0.6	2.6	-1.6	0.1	-0.9	-0.5	0.1	-0.6	-0.8	0.6
Father’s age at death	0.6	0.9	5.2	-0.4	-1.1	-2.3	-0.2	0.2	0.3	0.1	-0.2
Worrier / anxious feelings	0.1	0.3	1.4	0.1	0.3	1.2	0.1	-0.5	-0.0	0.3	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.0	0.9	-0.3	-1.0	0.1	0.2	-0.1	0.4	-0.1
Falls in the last year	0.5	0.6	3.3	-1.8	-0.5	-0.1	-0.3	1.0	0.4	-0.2	0.5
Hair/balding pattern: Pattern 3	0.5	0.8	2.8	-1.0	0.5	-1.7	0.1	1.3	0.7	0.3	0.1
Number of live births	0.3	0.4	1.5	0.8	0.7	-1.2	-0.2	0.1	0.0	0.5	0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.2	0.5	1.1	-0.6	-0.1	0.3	-0.1	0.3	0.2
Pulse rate	0.4	0.7	1.5	0.5	0.1	-0.7	0.7	1.0	0.7	1.1	-1.2
Happiness	0.4	0.5	1.7	-0.2	1.3	-0.6	-0.3	1.2	-0.2	-0.0	0.8
Noisy workplace	0.8	1.0	5.4	-0.7	-2.3	0.2	0.3	-1.0	0.2	-0.6	-0.7
Qualifications: A levels/AS levels or equivalent	1.0	2.2	4.3	1.8	0.8	-1.2	1.5	1.6	1.3	2.1	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.2	0.1	-1.1	0.5	0.0	-0.6	0.2	-0.6	-0.1
Mouth/teeth dental problems: Dentures	0.6	1.1	3.8	-0.0	1.9	-0.3	-1.3	-0.6	-1.1	-0.7	0.9
Asthma	0.6	1.2	2.7	0.7	-1.3	-0.3	1.2	1.6	1.2	1.1	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	2.3	0.4	0.3	1.5	0.3	1.1	0.3	0.6	-0.2
Medication: Cholesterol lowering	0.7	1.0	1.9	1.2	0.3	0.5	-0.8	-1.2	-1.4	-1.0	1.1
Depression (self-reported)	0.7	0.8	3.0	0.3	1.0	0.4	-0.0	-1.7	-1.5	-0.2	0.0
Medication: Lansoprazole	0.6	0.7	2.0	0.2	-1.4	-0.7	1.1	-0.2	1.0	0.2	-0.6
Prospective memory result	0.9	1.1	3.5	-0.1	0.1	-1.9	-1.4	-1.3	-1.2	-0.5	0.3
Lung cancer (father)	1.0	1.2	2.7	-0.4	0.1	1.1	1.0	1.6	1.1	1.4	-1.1
Illnesses of mother	1.4	1.7	3.3	-0.1	-1.8	0.8	0.6	1.4	1.6	1.4	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.4	0.3	0.6	-0.6	-0.3	0.1	-0.5	-0.2	0.5
Pulse wave Arterial Stiffness index	0.2	0.3	1.5	1.2	0.4	0.5	-0.1	-0.4	-0.1	0.1	0.5
Impedance of arm (left)	0.5	2.3	11.1	2.4	3.3	-0.1	1.0	-0.2	-0.5	0.7	0.2
Arm fat mass (right)	0.2	1.0	2.7	0.7	-1.7	-1.2	-0.7	-1.2	-0.4	-1.0	0.2
Trunk predicted mass	0.4	2.1	5.5	-2.3	-1.1	-0.3	-2.1	-0.5	-1.0	-1.7	1.3
Standing height	0.3	2.8	5.3	-2.0	1.6	-0.2	-2.3	-0.5	-1.8	-1.5	2.1
Length of working week for main job	0.3	0.3	0.7	-0.3	0.4	-0.6	-0.8	-0.2	-0.6	-0.7	0.4
Exposure to tobacco smoke at home	0.7	0.8	2.1	0.2	1.5	-1.5	-0.8	0.0	-0.5	-0.4	1.0
Breastfed as a baby	0.2	0.3	0.5	0.5	0.7	-0.6	-0.1	-0.7	-0.6	-0.2	0.4
Tense / ‘highly strung’	2.2	3.7	8.4	0.7	-0.5	-0.7	2.9	1.0	2.2	2.4	-2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.1	1.4	0.7	0.4	1.4	-0.3	0.2	1.0	-1.0
Hair/balding pattern: Pattern 4	0.3	0.8	2.1	0.8	-1.0	0.4	0.6	1.4	1.0	0.7	-0.6
Birth weight of first child	0.8	1.5	3.5	-0.6	1.1	-0.4	-1.5	-1.8	-1.9	-1.1	0.6
Peak expiratory flow (PEF)	0.1	0.3	1.0	1.0	0.3	-0.6	0.3	0.1	0.1	0.6	-0.5
Pulse wave reflection index	0.3	0.4	1.1	-0.8	-0.3	0.7	-0.6	-0.2	0.0	-0.6	1.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.1	1.0	-2.0	-1.6	0.8	-0.2	0.8	0.5	-0.9
Loud music exposure frequency	0.8	0.9	3.1	1.8	0.4	1.2	0.5	-0.8	0.0	0.5	-1.1
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	5.2	0.8	-0.9	1.3	1.3	2.3	1.6	1.2	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.8	0.8	-0.9	-0.5	0.1	-0.5	0.1	0.1	-0.5
Blood clot in the leg (DVT)	0.4	0.6	1.5	-0.1	-0.8	-0.4	1.2	-0.1	0.9	0.9	-0.9
Medication: Paracetamol	1.0	1.7	9.6	1.7	0.5	3.1	-0.2	0.4	-0.1	0.6	0.2
Headache pain in last month	0.4	0.6	2.1	-0.2	0.7	1.5	-0.3	-0.4	-0.9	-0.5	1.1
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.2	-0.3	-0.2	0.4	1.1	1.0	1.6	1.3	-1.8
Glaucoma (self-reported)	0.5	0.6	1.5	1.2	-0.9	-0.4	0.5	0.5	0.6	0.7	-0.8
Gout (self-reported)	1.6	2.1	4.0	1.4	1.3	0.1	-2.0	-1.2	-1.7	-1.4	1.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.2	0.3	1.5	0.9	-1.0	-1.2	-1.2	-0.7	0.9
Medication: Amlodipine	1.8	2.6	6.0	-0.5	1.0	-0.4	-1.8	-1.2	-2.3	-1.8	2.4
Medication: Ventolin 100micrograms inhaler	0.5	0.7	3.0	1.7	0.4	-0.4	0.8	0.9	0.1	0.7	-0.4
Birth weight	0.3	0.6	1.3	-0.9	-0.9	-1.1	-0.3	-0.4	-0.1	-1.1	0.7
Chronic bronchitis/emphysema (mother)	2.2	2.6	4.1	0.2	1.9	0.7	-1.4	-2.0	-2.0	-1.8	1.9
High blood pressure (siblings)	0.5	0.7	1.9	1.1	0.1	-0.2	1.4	0.1	0.7	0.8	-0.9
Forced vital capacity (FVC), Best measure	0.3	1.1	2.7	-0.5	1.6	-0.5	-1.2	0.5	-1.1	-0.6	1.6
Body fat percentage	0.3	1.0	2.8	1.7	-0.9	-1.0	-0.6	-1.3	-0.6	-0.9	0.2
Leg fat percentage (right)	0.3	0.9	2.9	1.7	-1.6	-0.6	0.4	-0.2	0.6	0.4	-0.9
Arm fat-free mass (right)	0.4	2.1	4.5	-2.1	-2.0	-0.1	-1.9	-0.8	-0.6	-1.7	0.8
Exposure to tobacco smoke outside home	0.2	0.3	0.9	0.4	0.9	0.1	0.2	0.8	0.2	0.8	-0.1
Comparative body size at age 10	0.6	1.6	8.5	0.5	-2.9	-1.5	0.5	-0.2	0.9	-0.0	-0.9
Number of full brothers	0.8	1.0	2.7	1.6	-0.6	0.8	1.3	0.7	0.8	0.8	-1.0
Worry too long after embarrassment	0.3	0.5	1.4	0.5	1.2	0.1	0.1	-1.1	-0.7	0.3	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.7	9.4	3.0	-1.6	-0.3	3.1	0.2	2.0	2.1	-2.8
Wheeze or whistling in the chest in last year	0.1	0.3	1.6	0.2	-0.4	-1.2	-0.1	0.4	0.1	0.2	-0.3
Number of children fathered	1.0	1.1	2.2	0.3	-1.5	0.3	1.2	0.9	1.4	0.8	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.9	-0.5	-0.9	-0.7	0.7	-0.0	0.8	-0.3	-0.5
Age at first live birth	1.1	1.9	4.0	0.4	-0.3	-1.9	2.0	-0.4	1.1	1.6	-1.8
Pulse wave peak to peak time	0.3	0.4	1.9	-1.4	-0.3	-0.6	0.1	0.5	0.1	-0.0	-0.4
Health satisfaction	0.6	0.8	2.4	1.3	0.8	-1.6	0.5	-0.1	-0.3	0.8	-0.8
Shortness of breath walking on level ground	1.1	1.3	6.3	0.4	-2.5	0.9	1.1	-0.2	0.8	-0.0	-1.0
Qualifications: College or University degree	0.5	1.5	3.1	1.3	0.4	-1.0	1.6	0.9	1.0	1.8	-1.3
Eye problems/disorders: None of the above	0.7	0.9	1.9	-0.3	0.8	1.1	-1.0	-0.6	-1.4	-0.8	1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.0	1.4	0.2	1.0	-0.1	-0.2	-0.3	-0.5	0.7
Emphysema/chronic bronchitis	0.1	0.1	0.6	0.1	-0.8	-0.2	-0.2	0.0	-0.1	-0.3	-0.3
Medication for pain relief, constipation, heartburn	0.4	0.6	1.3	-0.5	-0.6	-1.1	1.2	0.1	1.1	0.3	-0.8
Neck or shoulder pain in last month	0.6	0.9	2.7	1.6	0.1	-0.3	1.1	0.6	0.5	0.9	-1.3
Medication: Blood pressure	1.6	2.7	6.2	-1.0	0.3	-0.7	-1.6	-1.6	-2.1	-2.2	2.5
Angina (self-reported)	0.2	0.3	1.0	-0.1	-0.3	0.1	-1.0	-0.3	-0.5	-1.0	0.4
Migraine (self-reported)	0.4	0.5	1.4	0.6	-0.3	0.7	0.7	0.1	0.4	0.8	-1.2
Medication: Ibuprofen	0.4	0.5	1.5	-0.3	0.2	1.2	0.5	1.0	0.5	0.7	-0.2
Medication: Allopurinol	0.4	0.5	2.1	1.0	-0.1	0.3	-1.4	-0.4	-0.6	-0.3	0.7
Medication: Omeprazole	0.4	0.5	1.5	1.1	-0.2	-1.2	-0.2	-0.7	-0.6	-0.2	0.2
Medication: Seretide 50 evohaler	2.0	2.3	4.2	0.8	-0.6	-1.2	2.0	1.4	1.4	1.9	-2.0
Mean time to correctly identify matches	0.4	0.8	2.4	0.4	-1.4	-0.3	0.3	1.6	1.2	0.5	-0.5
Heart disease (mother)	0.5	0.7	4.5	0.4	0.1	-2.1	0.5	-0.3	0.1	0.3	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.4	6.4	-0.7	-2.5	-0.5	2.1	0.9	2.0	0.8	-1.5
Whole body fat mass	0.3	1.1	1.9	0.7	-1.1	-1.1	-1.1	-1.3	-0.9	-1.4	0.6
Leg fat mass (right)	0.2	0.8	2.2	0.6	-1.5	-0.9	-0.8	-1.1	-0.4	-1.0	0.1
Arm predicted mass (right)	0.5	2.7	5.2	-2.2	-1.9	-0.0	-2.3	-1.3	-1.1	-2.0	1.1
Pulse rate, automated reading	0.1	0.4	2.2	1.5	0.2	-0.1	0.3	0.3	0.2	0.5	-0.7
Alcohol intake frequency.	0.1	0.3	0.8	0.9	0.7	0.6	-0.0	-0.4	-0.4	-0.1	0.1
Comparative height size at age 10	0.3	1.7	4.7	-1.7	0.7	-0.0	-2.2	0.2	-0.9	-1.4	1.8
Number of full sisters	0.5	0.6	2.2	-0.7	-1.5	0.0	-0.5	-1.1	-0.3	-0.5	-0.6
Suffer from ‘nerves’	3.3	5.2	10.7	0.9	0.0	-3.1	3.3	1.9	2.4	2.4	-2.4
Overall health rating	0.9	1.9	3.1	1.7	1.1	-1.8	-0.9	-1.1	-1.7	-1.2	1.1
Chest pain or discomfort	1.0	1.4	2.8	0.8	-0.9	-0.5	1.4	1.1	1.6	1.2	-1.7
Had major operations	0.9	1.0	1.8	-0.9	1.2	-0.5	-1.3	-0.5	-1.3	-0.7	1.2
Age at last live birth	0.7	1.0	2.2	1.5	0.3	-1.1	1.3	-0.5	0.3	1.2	-0.9
Family relationship satisfaction	0.8	0.9	2.6	0.3	0.2	0.6	0.9	1.3	0.9	1.6	-1.1
Leg pain on walking	1.8	2.3	4.0	1.5	0.2	-2.0	-1.1	-1.9	-1.6	-1.4	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.6	0.4	-0.8	0.7	0.8	-0.5	0.0	-0.4	0.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.1	-1.7	-0.8	-1.1	-0.1	0.8	0.8	0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.3	-1.2	1.0	1.8	-0.1	1.4	0.2	1.1	-0.1
Medication: Aspirin	2.8	3.7	5.9	-0.3	0.5	-2.1	-2.4	-1.8	-2.4	-2.2	2.2
Supplements: Vitamin C	0.4	0.4	1.5	0.6	0.0	-1.2	0.7	-0.3	0.1	0.6	-0.8
Knee pain experienced in last month	0.8	1.2	3.6	1.9	0.7	-1.2	-0.7	-1.4	-0.9	-0.7	0.5
Hypertension (Self-reported)	1.0	2.7	6.5	0.5	0.2	-0.3	-1.4	-1.9	-2.1	-2.2	2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	4.0	0.8	0.4	-2.0	0.7	-0.4	-0.0	0.7	-1.0
Illnesses of father: Heart disease	2.9	4.0	9.6	0.3	3.1	-0.1	-2.1	-2.4	-2.6	-1.4	1.8
Illnesses of siblings: Diabetes	1.0	1.2	2.3	-0.8	1.4	-1.5	-0.9	-0.9	-0.9	-1.1	1.1
Smoking status: Previous	2.2	3.3	6.8	0.5	-1.0	0.8	2.5	1.2	2.3	2.6	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.5	0.2	0.5	-0.7	-1.2	-0.0	-0.7	-0.1	0.8
Whole body fat-free mass	0.4	2.6	5.3	-2.0	-1.4	-0.5	-2.3	-1.1	-1.2	-2.1	1.4
Leg fat-free mass (right)	0.7	3.7	8.0	-1.1	-1.1	-0.6	-2.7	-2.0	-2.0	-2.8	1.8
Arm fat percentage (left)	0.2	1.0	4.0	2.0	-1.0	-1.0	-0.1	-1.2	-0.3	-0.6	-0.2
Average weekly red wine intake	0.2	0.3	0.8	0.2	0.7	-0.5	-0.3	-0.6	-0.9	-0.4	0.4
Handedness (chirality/laterality): Left-handed	1.5	1.7	3.8	-0.2	-1.2	-0.1	1.4	1.9	2.0	1.4	-1.0
Mood swings	0.3	0.5	2.1	1.4	0.5	-0.2	0.6	0.3	0.4	0.7	-0.8
Loneliness, isolation	0.6	0.8	2.0	0.7	1.4	-1.0	-0.7	-0.8	-1.2	-0.2	0.7
Long-standing illness, disability or infirmity	0.9	1.3	9.1	0.8	0.6	-3.0	0.2	-0.3	-0.5	0.0	0.3
Ever had bowel cancer screening	0.6	0.7	3.6	0.2	0.8	-1.9	0.2	0.8	0.3	0.8	-0.2
Diabetes diagnosed by doctor	0.8	1.3	2.5	1.4	0.9	-0.9	-1.2	-1.3	-1.6	-0.7	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.2	0.5	-0.1	0.9	-1.1	0.7	-0.3	-0.1	0.6
Friendships satisfaction	0.4	0.5	1.3	-0.2	0.8	0.0	-1.2	0.0	-0.9	-0.4	1.0
Qualifications: nursing, teaching	0.6	1.0	1.9	0.4	-0.4	1.4	1.2	1.2	1.0	1.0	-0.8
Commuting to job workplace: Walk	0.5	0.6	2.6	1.6	0.4	-1.3	0.3	-0.4	-0.3	-0.2	0.0
Eye problems/disorders: Cataract	0.6	0.7	1.6	-0.2	-1.2	0.3	0.9	0.6	1.3	0.6	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.7	0.6	-0.5	-1.3	-0.5	0.4	-0.2	-0.2	0.6
Medication for cholesterol	2.1	3.1	9.1	1.0	-1.1	-0.4	2.4	0.4	1.3	2.5	-3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.6	6.2	-2.5	-0.1	-1.7	-0.8	-0.9	-0.5	-1.2	0.6
Back pain experienced in last month	1.1	1.6	3.2	1.1	-0.9	-0.2	1.0	1.2	1.3	1.8	-1.7
Mineral and other dietary supplements	2.4	3.2	8.6	0.5	-0.9	-2.9	1.3	2.2	1.6	1.9	-1.8
Breast cancer (self-reported)	0.9	1.0	4.2	2.1	0.9	-0.3	1.0	-0.8	0.2	1.1	-0.6
Asthma (self-reported)	0.6	1.1	2.6	1.0	-0.9	-0.3	1.2	1.6	1.0	1.1	-0.8
Osteoporosis (self-reported)	1.3	1.6	3.5	0.5	-1.5	-1.9	1.6	0.6	1.3	0.8	-1.3
Osteoarthritis (self-reported)	1.2	1.6	3.7	0.3	-1.0	-0.7	-1.9	-1.4	-1.3	-1.7	1.1
Medication: Aspirin	3.0	3.9	7.4	-0.4	0.9	-1.4	-2.6	-1.9	-2.7	-2.2	2.4
Medication: Gliclazide	0.5	0.6	1.0	0.2	-0.5	-0.8	0.4	0.8	1.0	0.9	-1.0
Illnesses of father: None of the above (group 1)	1.7	2.1	3.4	0.2	-1.6	-0.2	1.5	1.8	1.9	1.5	-1.7
Smoking status: Current	0.6	1.0	2.2	-1.5	-0.9	-0.8	-1.2	-0.6	-0.7	-1.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.7	0.6	0.6	-0.2	0.2	0.8	0.3	0.8	-0.1
Whole body water mass	0.5	2.6	5.5	-1.9	-1.4	-0.4	-2.3	-1.2	-1.3	-2.1	1.4
Leg predicted mass (right)	0.7	3.7	8.0	-1.0	-1.1	-0.5	-2.7	-2.1	-2.1	-2.8	1.9
Arm fat mass (left)	0.2	0.8	2.1	0.9	-1.5	-1.2	-0.5	-1.0	-0.3	-0.8	-0.1
Number of self-reported non-cancer illnesses	1.8	3.1	6.0	1.4	-0.0	-1.2	-1.6	-1.7	-2.2	-2.5	2.2
Average weekly champagne plus white wine intake	1.7	2.3	6.2	2.4	-0.2	-0.0	0.7	2.5	1.4	1.9	-0.7
Miserableness	0.6	1.1	3.2	0.0	0.7	1.1	0.6	1.8	0.9	1.5	-0.6
Guilty feelings	0.2	0.3	0.5	-0.7	0.5	-0.6	-0.3	-0.6	-0.5	0.2	-0.3
Wears glasses or contact lenses	0.4	0.5	2.1	1.5	-0.9	-0.2	0.8	-0.2	0.2	-0.1	-0.4
Ever taken oral contraceptive pill	0.9	1.0	2.7	1.0	1.7	1.1	0.4	1.4	-0.1	1.1	0.1
Hearing aid user	0.8	0.9	2.4	0.3	0.4	-1.4	-1.3	-0.0	-0.6	-0.8	1.5
Mother’s age at death	2.2	2.7	5.4	0.4	1.9	-0.1	-1.9	-1.2	-1.8	-2.1	2.3
Financial situation satisfaction	0.7	0.8	2.2	1.1	-1.5	-0.7	1.1	-0.0	0.7	0.1	-1.0
Tinnitus: Yes, now most or all of the time	1.2	1.4	3.2	-0.1	-0.9	-1.8	-1.0	-1.4	-0.7	-1.6	1.3
Commuting to job workplace: Public transport	0.5	0.7	1.7	1.0	1.3	1.2	-0.2	-0.6	-0.6	-0.1	0.5
Eye problems/disorders: Glaucoma	0.3	0.4	1.0	0.3	-1.0	-0.1	0.4	0.6	0.7	0.6	-0.8
Medication: Blood pressure	0.3	0.6	2.0	0.8	0.4	-0.3	-0.9	-0.0	-0.4	-0.9	1.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.7	0.1	-0.3	0.2	0.3	-0.1	0.1	0.4	-0.9
Supplements: Fish oil (including cod liver oil)	4.7	6.1	9.0	-1.4	1.5	1.9	-3.0	-2.5	-2.9	-3.0	2.8
High cholesterol (Self-reported)	0.4	0.7	1.3	1.1	0.7	0.2	-0.8	-0.8	-0.9	-0.7	1.1
Medication: Bendroflumethiazide	2.0	3.0	7.8	0.8	0.6	0.4	-2.0	-1.4	-1.8	-2.3	2.8
Medication: Paracetamol	0.9	1.4	9.0	0.8	0.2	3.0	-0.2	0.7	0.0	0.9	0.1
Medication: Lisinopril	1.0	1.4	3.2	-1.3	-0.1	-1.8	-1.0	-0.6	-0.8	-1.3	1.5
Medication: Atorvastatin	0.7	0.9	2.3	-0.9	0.4	-0.9	-0.8	-0.3	-0.7	-1.4	1.5
Illnesses of father: High blood pressure	0.2	0.2	1.0	-0.3	-0.3	1.0	-0.5	0.2	0.1	-0.2	0.3
Alcohol drinker status: Never	1.0	1.2	3.5	-0.0	-0.3	0.6	-1.0	-1.0	-1.2	-1.9	1.4
Ever smoked	0.5	0.9	2.6	-1.1	-1.6	-0.5	0.8	0.1	1.1	0.7	-1.0
Basal metabolic rate	0.4	2.1	4.3	-1.5	-1.4	-0.6	-2.1	-1.1	-1.2	-1.9	1.2
Leg fat percentage (left)	0.2	0.7	2.4	1.5	-1.4	-0.8	-0.1	-0.7	0.1	-0.3	-0.4
Arm fat-free mass (left)	0.4	2.0	4.2	-2.0	-2.0	-0.4	-1.8	-0.8	-0.6	-1.7	0.9
Number of operations (self-reported)	2.2	3.2	7.6	-1.6	1.0	-0.3	-1.5	-2.7	-2.5	-2.1	1.4
Average weekly beer plus cider intake	1.0	1.5	2.8	1.6	-1.7	-0.6	1.1	-1.2	0.3	0.8	-1.6
Irritability	0.7	1.1	4.0	2.0	1.0	-0.0	0.3	1.0	0.1	1.4	-0.9
Risk taking	0.1	0.1	0.2	-0.3	-0.1	0.5	0.2	-0.4	-0.3	-0.0	-0.4
Ever had prostate specific antigen (PSA) test	0.4	0.4	3.0	1.7	-0.0	-0.1	0.0	-0.3	-0.4	0.2	0.3
Fractured/broken bones in last 5 years	0.5	0.6	2.0	0.5	-0.8	-1.4	0.3	-1.2	-0.1	-0.3	-0.4
Age started oral contraceptive pill	0.3	0.4	2.4	1.6	-0.1	0.8	0.1	-0.2	0.1	-0.1	0.4
Diastolic blood pressure, automated reading	0.1	0.4	1.4	0.3	-1.2	-0.1	0.8	-0.3	0.5	0.3	-0.7
Ever depressed for a whole week	0.4	0.5	1.8	-1.2	0.1	-1.4	-0.0	-0.7	-0.3	-0.4	-0.1
Unable to work because of sickness or disability	0.4	0.6	1.8	1.4	1.0	-1.0	-0.3	-0.5	-0.7	0.2	0.2
Commuting to job workplace: Cycle	0.5	0.6	1.5	-0.8	-1.2	-0.8	0.7	-0.7	0.7	-0.3	-0.4
Myopia	1.6	2.3	5.0	1.7	0.9	-1.2	-1.2	-2.2	-2.1	-1.1	1.2
Vascular/heart problems diagnosed by doctor	2.0	5.5	11.4	0.7	-0.4	0.7	2.7	2.3	2.8	3.3	-3.4
Cholesterol lowering medication	1.2	1.8	4.3	-0.5	0.5	-0.3	-2.1	-0.9	-1.2	-2.0	1.8
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.6	1.6	0.0	-1.0	0.1	-0.2	-0.3	0.5	-0.1
Pain experienced in last month	1.4	2.4	5.4	-2.3	0.1	-0.1	-2.0	-0.6	-1.3	-1.9	1.9
Supplements: Calcium	3.5	3.9	5.7	0.7	2.1	1.3	-1.9	-2.3	-2.4	-2.2	2.2
Basal cell carcinoma (self-reported)	0.8	1.0	4.1	1.1	-0.6	2.0	0.7	0.7	0.8	0.7	-0.2
Heart attack/myocardial infarction (self-reported)	1.3	1.7	3.6	-0.4	1.0	0.1	-1.3	-1.6	-1.9	-1.6	1.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.7	-0.1	-1.0	-0.6	1.3	-0.3	0.9	0.7	-0.8
Heart disease (siblings)	0.2	0.3	0.7	0.8	-0.1	0.3	-0.6	-0.3	-0.5	-0.6	0.3
Alcohol drinker status: Previous	1.4	1.6	3.5	0.6	-0.5	0.8	1.9	0.7	1.2	1.9	-1.6
Pack years of smoking	1.7	2.6	6.0	-0.1	0.4	-0.2	-2.1	-1.7	-1.8	-2.5	1.9
Impedance of whole body	0.4	2.0	9.7	1.7	3.1	0.2	1.2	0.7	0.2	1.3	-0.1
Leg fat mass (left)	0.3	1.0	2.4	0.6	-1.5	-1.0	-1.0	-1.2	-0.6	-1.2	0.3
Arm predicted mass (left)	0.4	2.1	4.1	-2.0	-2.0	-0.3	-1.9	-0.8	-0.7	-1.7	0.9