Hub : Genes

SNX25

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1170 0.0390 2.1e-03 0.044 0.015 0.031 0.018 0.030 4.4e-06 5.5e-03 9.9e-05 2.7e-03 1.3e-04
2 GTEx Cells EBV-transformed lymphocytes 0.3640 0.1020 1.9e-03 0.079 NA 0.030 NA 0.019 1.5e-03 NA 3.6e-02 NA 7.8e-02
3 GTEx Heart Atrial Appendage 0.2890 0.0920 5.6e-03 0.013 NA 0.007 NA 0.024 7.9e-02 NA 1.4e-01 NA 2.9e-02
4 NTR Blood 0.0485 0.0125 1.3e-07 0.029 0.024 0.021 0.027 0.029 7.2e-10 2.2e-08 2.0e-07 3.8e-09 7.2e-10
5 TCGA Cervical Squamous Cell Carcinoma 0.1090 0.0530 3.7e-04 0.032 0.048 0.055 NA 0.038 1.0e-02 2.0e-03 1.1e-03 NA 5.9e-03
6 TCGA Brain Lower Grade Glioma 0.0196 0.0112 5.1e-03 0.022 0.022 0.005 NA 0.010 1.2e-03 1.3e-03 7.8e-02 NA 2.1e-02
7 TCGA Prostate Adenocarcinoma 0.0426 0.0221 2.7e-04 0.014 0.029 0.014 NA 0.012 1.2e-02 5.0e-04 1.2e-02 NA 1.9e-02
8 TCGA Thyroid Carcinoma 0.2080 0.0560 0.0e+00 0.265 0.296 0.317 NA 0.315 9.0e-26 3.6e-29 2.0e-31 NA 2.8e-31

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.4 1.5 -0.5 -0.6 1.2 -0.2 -0.7 -0.2 -0.4 0.0
Bipolar Disorder or Schizophrenia 0.4 1.1 3.3 0.4 -0.2 0.2 -1.1 -1.8 -1.2 -1.3 0.8
Depressed Affect (Nagel 2018) 0.3 0.7 1.6 0.4 -0.3 0.4 0.8 1.0 1.0 1.3 -0.9
Depression (Nagel 2018) 0.1 0.1 0.3 0.4 0.4 0.1 -0.5 0.5 -0.1 0.5 0.1
Intelligence (Savage-Jansen 2018) 1.0 3.1 6.0 0.3 -2.3 0.6 1.7 1.1 2.2 2.1 -2.5
Neuroticism (Nagel 2018) 1.2 2.8 5.7 1.4 -0.3 -0.9 2.1 1.1 1.7 2.4 -2.3
Schizophrenia (2018) 0.7 1.4 3.0 0.9 0.3 -0.8 -1.3 -1.7 -1.4 -1.4 1.0
Schizophrenia vs Biploar Disorder 0.2 0.2 1.1 -0.0 0.1 0.0 0.1 -0.5 -0.4 -1.0 0.5
Worry (Nagel 2018) 1.4 3.0 6.0 0.9 -0.7 -1.6 2.5 1.3 2.0 2.1 -2.0
Alzheimer’s Disease (in mother) 0.3 0.4 1.5 1.2 0.5 0.5 -0.1 0.7 -0.0 -0.2 0.8
Alzheimer’s Disease (in father) 2.0 2.1 4.6 1.6 -0.6 0.3 1.5 1.3 1.5 2.1 -1.9
Alzheimer’s Disease (including proxy) 0.8 1.2 6.0 2.4 0.7 -0.6 0.7 0.9 0.3 1.0 -0.2
Crohns Disease (2017) 0.4 0.8 2.5 0.4 -1.6 0.1 0.2 -0.4 0.6 0.8 -1.6
Irritable Bowel Disease (IBD) 0.3 0.8 1.9 1.2 -0.5 -0.4 0.1 0.3 0.8 1.4 -1.3
Ulcerative Colitis (UC) 0.4 0.7 2.0 1.4 1.0 -0.3 0.2 0.6 0.5 1.3 -0.5
Major Depression (MDD) 2.2 2.7 4.7 0.9 1.1 -2.2 -1.9 -0.7 -1.7 -2.0 1.8
Reaction Time 0.9 1.6 3.2 1.0 -1.8 0.6 1.0 1.5 1.6 1.1 -1.1
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.8 -0.4 -0.9 0.4 -0.7 0.3 0.1 -0.1 0.0
Breast Cancer 0.3 0.8 3.7 -0.2 -0.1 1.9 -0.5 0.2 -0.3 -0.8 1.1
Ovarian Cancer 0.7 0.9 3.3 -0.3 0.3 0.4 -0.9 -0.0 -0.5 -1.5 1.8
Prostate Cancer 0.3 0.5 2.3 -1.5 -0.1 -0.9 0.1 0.1 -0.1 -0.6 0.4
Age at First Birth 0.7 1.0 5.8 -2.4 -0.4 -1.0 0.7 -0.0 0.5 0.0 -0.5
Bipolar Disorder (2011) 0.3 0.3 0.7 0.5 0.7 -0.9 -0.3 -0.3 -0.3 -0.4 0.3
Body Mass Index (BMI) (2010) 0.4 0.5 0.8 0.7 -0.5 -0.9 0.9 0.5 0.5 0.8 -0.8
Coronary Artery Disease (CAD) 3.5 4.1 9.3 -2.8 -0.3 0.9 -3.1 -0.5 -1.8 -2.6 2.1
Crohns Disease (2012) 1.2 1.9 3.7 -0.8 -1.6 -0.6 0.8 1.9 1.8 1.3 -1.5
Mean Putamen Volume 0.2 0.2 1.1 -0.2 1.0 -0.2 -0.3 0.6 -0.2 0.2 0.2
Fasting Glucose 1.5 1.8 3.1 -1.3 -1.4 0.0 1.4 1.2 1.5 1.3 -1.8
HbA1C 0.1 0.1 0.4 0.5 0.1 -0.0 0.0 0.3 0.1 0.6 -0.7
HDL Cholesterol 0.4 0.6 1.8 0.6 -1.3 1.4 -0.1 0.8 0.6 0.2 -0.4
LDL Cholesterol 0.1 0.2 0.7 -0.6 0.8 0.3 -0.3 -0.6 -0.5 -0.1 0.3
Lupus 0.1 0.2 0.7 -0.1 0.3 0.3 -0.3 0.8 0.2 0.0 0.6
Neuroticism (2016) 1.3 1.9 4.3 2.1 0.7 -0.9 0.9 1.5 1.2 2.0 -1.2
Primary Biliary Cirrhosis 0.4 0.5 1.7 0.9 1.3 0.7 -0.2 -0.1 -0.7 -0.4 0.8
Rheumatoid Arthritis 0.4 0.6 1.5 0.8 -0.9 -1.2 -0.3 -0.8 -0.5 -0.3 0.5
Schizophrenia (2014) 1.6 3.6 8.2 -0.5 0.1 0.1 -1.9 -2.8 -2.2 -2.9 2.0
Triglycerides 0.4 0.6 1.2 -0.5 -0.6 -1.1 0.8 0.8 0.8 0.9 -0.8
Type 2 Diabetes (T2D) (2012) 0.1 0.2 1.0 0.1 0.3 0.4 0.1 -1.0 -0.2 -0.2 0.1
Ulcerative Colitis 0.6 0.8 2.1 1.4 0.7 0.5 0.5 0.6 0.5 1.4 -0.9
Blood Eosinophil Count 0.4 3.2 5.7 2.0 -1.2 0.4 1.9 1.4 1.9 2.3 -2.4
Blood Platelet Count 0.1 0.8 2.5 -0.9 -1.0 1.6 0.1 1.1 0.7 0.3 -0.7
Blood Red Count 0.1 1.4 2.8 -0.8 1.6 0.3 -1.6 -1.1 -1.7 -0.6 1.0
Blood White Count 0.1 0.6 2.1 -1.0 -1.4 0.5 0.7 -0.4 0.6 -0.4 -0.7
Heel T-Score 0.3 2.3 4.0 0.8 0.8 -1.2 -1.8 -1.8 -2.0 -1.9 1.1
BMI 0.2 1.1 7.7 0.3 -2.8 -0.3 0.2 -0.0 0.7 -0.2 -0.7
Height 0.2 3.5 9.5 0.0 3.1 0.6 -2.3 -0.7 -2.4 -0.9 2.4
Waist Hip Ratio (WHR) 0.3 1.1 2.6 -1.5 -1.6 -0.7 0.3 0.6 1.3 0.8 -1.1
Systolic Blood Pressure 0.4 2.1 4.6 1.1 2.1 -0.3 -1.6 -0.7 -1.7 -1.0 2.0
Smoking Status 0.4 0.9 2.1 -0.9 -1.5 -0.5 0.7 0.3 1.1 0.9 -1.2
Allergy or Eczema 0.4 1.1 4.2 1.8 -0.1 -2.0 0.5 0.6 0.2 0.4 -0.5
Cardiovascular Disease 0.1 0.3 0.9 0.6 -0.9 -0.4 0.0 -0.1 -0.1 -0.4 0.8
Hypothyroidism (self reported) 0.1 0.2 0.7 0.7 0.8 0.5 0.1 -0.1 -0.0 0.6 -0.3
Respiratory disease 0.4 0.8 3.4 1.8 -0.7 -0.2 1.0 0.5 0.6 0.5 -0.8
Type 2 Diabetes (T2D) (2018) 0.3 0.5 1.9 0.3 -0.4 -1.4 -0.2 -1.1 -0.5 0.2 -0.5
Lung FEV1/FVC ratio 0.2 0.9 5.0 -0.4 -1.1 -2.2 -0.5 -0.5 0.0 -0.0 -0.9
Lung FVC 0.1 0.4 1.1 0.5 0.8 0.0 -0.4 0.2 -0.8 -0.3 1.1
Neuroticism 0.4 0.9 2.6 1.6 0.9 -1.0 0.4 0.6 0.4 1.3 -0.6
Chronotype (morning person) 0.1 0.1 0.5 -0.1 0.7 0.6 0.0 0.2 0.2 0.3 -0.1
Hair Pigment 0.5 14.1 33.8 0.9 -2.2 0.9 5.8 3.6 5.0 4.2 -4.2
Tanning 0.1 0.8 2.2 1.5 0.9 -0.2 -0.7 -1.0 -1.1 -0.1 0.2
Hand grip strength (left) 0.2 0.5 1.8 -1.4 -0.6 -0.3 -0.6 -0.5 -0.0 -0.8 0.3
Number of treatments/medications taken 0.8 1.5 4.3 -0.6 1.4 0.4 -0.9 -0.6 -1.6 -1.2 2.1
Average weekly spirits intake 0.7 0.9 3.0 1.0 1.6 1.7 0.0 0.4 -0.3 0.5 0.0
Sensitivity / hurt feelings 0.5 0.9 2.3 0.1 -0.9 -0.5 0.9 0.3 1.3 1.2 -1.5
Frequency of depressed mood in last 2 weeks 0.9 1.3 4.7 1.5 2.2 0.3 -1.1 -0.1 -1.2 0.3 0.8
Hearing difficulty/problems: Yes 0.7 1.1 2.2 -0.2 -1.5 -1.0 -1.2 -0.6 -0.5 -1.4 1.2
Relative age of first facial hair 0.4 0.8 3.3 0.3 -1.8 -0.2 0.6 -0.4 0.8 0.4 -1.1
Other serious medical condition/disability diagnosed by doctor 0.9 1.1 5.5 -0.4 1.5 -2.4 -0.6 0.4 -0.6 0.1 0.5
Ever used hormone-replacement therapy (HRT) 1.2 1.6 2.9 -0.8 0.1 1.7 -1.6 0.1 -0.8 -1.7 1.7
Ever had hysterectomy (womb removed) 2.7 3.1 4.7 -1.6 1.6 0.2 -1.9 -1.9 -2.2 -1.9 1.9
Systolic blood pressure, automated reading 0.0 0.1 0.3 0.0 0.1 0.5 0.5 0.3 0.4 0.2 0.0
Eye problems/disorders: Diabetes related eye disease 0.9 0.9 5.6 0.3 -0.4 -2.4 -0.1 1.0 0.3 0.7 -0.2
Angina 0.2 0.2 0.8 -0.1 -0.3 0.3 -0.7 -0.2 -0.3 -0.9 0.2
Medication for hormone replacement therapy 3.4 3.8 8.4 -2.1 1.0 0.8 -2.3 -0.7 -1.6 -2.7 2.9
Vitamin and mineral supplements 0.5 0.6 3.1 -0.2 -0.2 1.8 -0.3 1.2 0.4 0.1 -0.2
Supplements: Zinc 0.6 0.7 2.0 0.1 1.4 0.8 0.6 -0.7 -0.2 1.1 -0.6
Medication: Co-codamol 0.5 0.5 2.0 -0.0 -0.2 -1.3 0.0 -1.4 -0.1 -0.6 0.2
Medication: Metformin 1.1 1.5 4.0 0.8 0.1 -1.0 -1.0 -2.0 -1.6 -1.4 1.0
Diabetes (father) 2.1 2.6 5.6 2.2 1.0 -2.4 -1.5 -0.2 -1.0 -1.5 2.0
Diabetes (mother) 1.1 1.4 4.2 0.5 0.9 0.1 -1.3 -0.5 -1.2 -1.6 2.0
Severe depression (siblings) 6.5 7.3 12.7 0.9 3.1 -1.1 -2.7 -2.7 -3.6 -2.6 3.5
Pack years adult smoking proportion 1.7 2.5 5.7 -0.4 0.5 -0.4 -2.1 -1.5 -1.8 -2.4 2.0
Impedance of leg (right) 0.5 2.6 6.1 0.6 1.7 0.5 1.9 1.9 1.6 2.5 -1.3
Leg fat-free mass (left) 0.6 3.1 6.6 -1.2 -1.4 -0.7 -2.4 -1.8 -1.7 -2.6 1.5
Trunk fat percentage 0.3 1.2 3.2 1.8 -0.5 -0.9 -0.7 -1.6 -0.9 -1.1 0.4
Hand grip strength (right) 0.1 0.1 0.4 -0.2 -0.6 -0.3 0.1 -0.6 0.2 -0.3 -0.3
Townsend deprivation index at recruitment 1.0 1.3 2.4 0.6 1.1 -1.1 -1.0 -1.1 -1.5 -1.1 1.4
Current tobacco smoking 0.4 0.7 2.2 -1.5 -0.8 -0.6 -0.7 -0.4 -0.4 -1.0 0.2
Average weekly fortified wine intake 0.6 0.7 2.0 -0.4 1.3 -1.4 0.4 0.6 -0.3 0.0 1.1
Maternal smoking around birth 0.4 0.6 1.3 -0.8 -0.4 0.8 -0.5 -1.2 -0.7 -1.0 0.2
Fed-up feelings 0.4 0.7 2.1 0.2 -1.0 -1.4 0.5 0.7 0.8 0.6 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.0 0.3 0.7 -0.9 -0.5 0.4 -0.2 1.0 -0.3
Relative age voice broke 0.4 0.5 1.8 0.2 -1.3 -0.1 1.1 -0.9 0.4 -0.2 -0.6
Taking other prescription medications 0.9 1.4 2.8 -0.5 1.5 -0.1 -0.6 -1.4 -1.7 -1.4 1.4
Age when periods started (menarche) 0.5 1.1 3.7 0.0 0.5 0.6 1.9 1.0 1.0 1.3 -1.0
Bilateral oophorectomy (both ovaries removed) 2.1 2.4 4.0 -2.0 1.5 -0.2 -1.7 -1.6 -1.7 -1.5 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.9 1.9 5.6 -0.2 1.2 0.3 -2.4 0.6 -1.4 -1.5 1.9
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 3.5 -0.9 -0.7 1.7 1.6 0.1 1.1 1.0 -1.9
Qualifications: CSEs or equivalent 0.6 0.8 2.4 1.1 -0.2 0.2 1.6 0.2 0.6 1.2 -0.8
Serious illness, injury or assault to yourself 1.1 1.4 4.0 1.4 -1.2 -2.0 1.1 -0.9 0.7 0.5 -1.0
High blood pressure 1.1 3.1 8.0 0.2 0.1 -0.4 -1.8 -1.6 -2.1 -2.5 2.8
Hayfever, allergic rhinitis or eczema 0.7 1.4 5.8 2.4 0.9 -2.1 -0.1 0.5 -0.3 0.2 0.1
Multivitamins +/- minerals 0.5 0.7 1.2 -1.1 0.1 -0.3 -0.2 -1.1 -1.0 -0.8 1.0
Stomach or abdominal pain in last month 0.4 0.5 2.8 -0.3 0.2 -1.7 0.5 0.5 0.3 0.6 -0.0
Supplements: Glucosamine 1.0 1.3 3.6 -0.7 0.5 1.9 -0.9 -1.3 -0.9 -1.2 1.2
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 2.0 0.5 0.2 -1.4 0.6 0.4 0.1 0.7 -0.1
Medication: Atenolol 2.4 3.0 6.6 -2.6 0.7 -0.4 -2.2 -0.4 -1.3 -2.1 2.3
Medication: Levothyroxine sodium 0.1 0.1 0.7 0.1 0.2 0.1 -0.8 -0.2 -0.2 -0.1 0.5
Sitting height 0.3 2.5 5.5 -1.0 2.2 -0.4 -2.3 0.3 -1.8 -1.1 1.9
Chronic bronchitis/emphysema (father) 0.3 0.4 1.3 -0.3 0.1 0.0 -0.2 -1.1 -0.7 -0.8 0.8
High blood pressure (mother) 0.5 0.7 2.0 -0.4 1.0 0.1 -0.6 -0.2 -0.9 -0.9 1.4
Body mass index (BMI) 0.3 1.1 4.9 0.8 -2.2 -0.8 -0.4 -1.2 -0.2 -0.9 -0.2
Impedance of leg (left) 0.4 1.9 5.0 0.7 2.2 0.5 1.4 1.5 1.0 1.9 -0.6
Leg predicted mass (left) 0.6 3.0 6.3 -1.1 -1.4 -0.7 -2.3 -1.8 -1.7 -2.5 1.4
Trunk fat mass 0.3 1.4 2.7 1.0 -0.8 -0.9 -1.2 -1.6 -1.2 -1.5 0.8
Waist circumference 0.3 1.0 4.9 0.6 -2.2 -1.0 -0.6 -0.8 0.0 -0.8 -0.2
Number of incorrect matches in round 1.5 2.4 4.2 -0.6 0.9 1.8 -1.5 -1.5 -1.8 -1.8 2.0
Past tobacco smoking 0.7 1.2 2.1 0.4 1.2 -0.7 -1.4 -0.4 -1.4 -1.3 1.4
Alcohol usually taken with meals 0.5 0.8 2.2 0.5 1.3 -0.5 0.5 1.5 0.3 1.2 0.2
Nervous feelings 1.4 2.6 4.8 1.1 -1.6 -0.2 1.9 1.3 2.2 1.8 -2.0
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.2 6.2 2.5 0.1 -0.9 1.4 0.9 1.0 2.0 -1.7
Hearing difficulty/problems with background noise 0.5 0.8 2.1 -0.7 -0.3 -0.5 -1.4 -0.3 -0.9 -1.2 1.2
Hair/balding pattern: Pattern 2 0.8 1.0 2.4 0.1 -0.8 0.2 1.5 -0.4 1.1 1.2 -1.4
Had menopause 0.9 1.1 3.7 -0.3 1.0 -0.3 -0.6 -1.9 -1.1 -1.2 0.9
Had other major operations 0.6 0.7 2.4 -0.1 1.5 -1.2 0.4 -1.2 -0.7 0.1 -0.2
Forced vital capacity (FVC) 0.2 0.8 3.6 0.3 1.9 -0.4 -0.7 0.3 -0.8 -0.2 1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.0 6.8 -0.2 0.9 -0.7 -2.6 1.0 -1.4 -1.3 1.9
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 2.0 -0.6 -0.1 -1.4 1.0 -0.0 0.4 0.6 -0.8
Qualifications: None of the above 1.3 2.7 6.5 -1.2 0.5 -1.6 -2.5 -0.8 -1.6 -2.1 1.8
Financial difficulties in last 2 years 0.5 0.7 2.2 1.3 -0.7 0.1 0.2 -1.5 -0.4 -0.9 -0.1
Mouth/teeth dental problems 0.2 0.2 1.0 -1.0 -0.7 0.3 0.2 -0.2 0.1 -0.5 0.0
Heart attack 1.5 1.9 4.3 -0.3 1.1 -0.2 -1.4 -1.8 -2.1 -1.6 1.4
Allergy 0.7 1.6 5.5 -2.3 0.2 1.7 -0.8 -1.2 -0.7 -1.0 0.8
Pain all over the body in last month 0.5 0.5 3.3 1.8 0.1 0.7 -0.2 0.4 0.1 0.6 -0.1
Diabetes (self-reported) 0.4 0.6 1.2 0.7 0.5 -0.8 -1.0 -0.6 -1.1 -0.4 0.6
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.8 0.9 -0.2 0.4 0.5 -0.5 -0.3 0.1 -0.1
Medication: Ramipril 1.0 1.3 3.4 0.9 0.7 -1.8 -0.7 -0.3 -1.2 -0.9 1.7
Medication: Simvastatin 0.2 0.2 0.8 0.6 -0.4 0.0 -0.9 -0.5 -0.2 -0.3 0.3
Fluid intelligence score 0.4 0.8 3.0 1.1 -0.6 1.7 0.3 1.0 0.7 0.7 -0.6
Illnesses of siblings 0.2 0.2 1.0 -0.2 -1.0 -0.0 0.1 0.2 0.5 0.3 -0.5
Neuroticism score 0.4 0.8 1.9 1.1 1.1 -0.6 0.7 0.7 0.5 1.4 -1.0
Weight 0.2 1.1 2.0 -0.1 -1.3 -0.7 -1.4 -1.2 -0.9 -1.4 0.7
Impedance of arm (right) 0.5 2.2 12.6 1.7 3.5 0.2 0.7 0.1 -0.7 0.4 0.7
Arm fat percentage (right) 0.2 0.8 2.5 1.6 -0.9 -1.2 -0.2 -1.0 -0.4 -0.7 0.1
Trunk fat-free mass 0.4 2.1 5.7 -2.4 -1.2 -0.3 -2.0 -0.5 -0.9 -1.6 1.2
Hip circumference 0.1 0.6 1.9 1.4 -1.1 -0.7 -0.4 -0.6 -0.3 -0.7 0.3
Time employed in main current job 3.1 3.6 8.2 -0.6 1.5 -0.3 -2.9 -1.0 -2.1 -2.3 2.6
Alcohol intake versus 10 years previously 0.4 0.6 2.6 -1.6 0.1 -0.9 -0.5 0.1 -0.6 -0.8 0.6
Father’s age at death 0.6 0.9 5.2 -0.4 -1.1 -2.3 -0.2 0.2 0.3 0.1 -0.2
Worrier / anxious feelings 0.1 0.3 1.4 0.1 0.3 1.2 0.1 -0.5 -0.0 0.3 -0.6
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.0 0.9 -0.3 -1.0 0.1 0.2 -0.1 0.4 -0.1
Falls in the last year 0.5 0.6 3.3 -1.8 -0.5 -0.1 -0.3 1.0 0.4 -0.2 0.5
Hair/balding pattern: Pattern 3 0.5 0.8 2.8 -1.0 0.5 -1.7 0.1 1.3 0.7 0.3 0.1
Number of live births 0.3 0.4 1.5 0.8 0.7 -1.2 -0.2 0.1 0.0 0.5 0.4
Forced expiratory volume in 1-second (FEV1) 0.1 0.2 1.2 0.5 1.1 -0.6 -0.1 0.3 -0.1 0.3 0.2
Pulse rate 0.4 0.7 1.5 0.5 0.1 -0.7 0.7 1.0 0.7 1.1 -1.2
Happiness 0.4 0.5 1.7 -0.2 1.3 -0.6 -0.3 1.2 -0.2 -0.0 0.8
Noisy workplace 0.8 1.0 5.4 -0.7 -2.3 0.2 0.3 -1.0 0.2 -0.6 -0.7
Qualifications: A levels/AS levels or equivalent 1.0 2.2 4.3 1.8 0.8 -1.2 1.5 1.6 1.3 2.1 -1.2
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.3 1.2 0.1 -1.1 0.5 0.0 -0.6 0.2 -0.6 -0.1
Mouth/teeth dental problems: Dentures 0.6 1.1 3.8 -0.0 1.9 -0.3 -1.3 -0.6 -1.1 -0.7 0.9
Asthma 0.6 1.2 2.7 0.7 -1.3 -0.3 1.2 1.6 1.2 1.1 -0.9
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.6 2.3 0.4 0.3 1.5 0.3 1.1 0.3 0.6 -0.2
Medication: Cholesterol lowering 0.7 1.0 1.9 1.2 0.3 0.5 -0.8 -1.2 -1.4 -1.0 1.1
Depression (self-reported) 0.7 0.8 3.0 0.3 1.0 0.4 -0.0 -1.7 -1.5 -0.2 0.0
Medication: Lansoprazole 0.6 0.7 2.0 0.2 -1.4 -0.7 1.1 -0.2 1.0 0.2 -0.6
Prospective memory result 0.9 1.1 3.5 -0.1 0.1 -1.9 -1.4 -1.3 -1.2 -0.5 0.3
Lung cancer (father) 1.0 1.2 2.7 -0.4 0.1 1.1 1.0 1.6 1.1 1.4 -1.1
Illnesses of mother 1.4 1.7 3.3 -0.1 -1.8 0.8 0.6 1.4 1.6 1.4 -1.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 0.4 0.3 0.6 -0.6 -0.3 0.1 -0.5 -0.2 0.5
Pulse wave Arterial Stiffness index 0.2 0.3 1.5 1.2 0.4 0.5 -0.1 -0.4 -0.1 0.1 0.5
Impedance of arm (left) 0.5 2.3 11.1 2.4 3.3 -0.1 1.0 -0.2 -0.5 0.7 0.2
Arm fat mass (right) 0.2 1.0 2.7 0.7 -1.7 -1.2 -0.7 -1.2 -0.4 -1.0 0.2
Trunk predicted mass 0.4 2.1 5.5 -2.3 -1.1 -0.3 -2.1 -0.5 -1.0 -1.7 1.3
Standing height 0.3 2.8 5.3 -2.0 1.6 -0.2 -2.3 -0.5 -1.8 -1.5 2.1
Length of working week for main job 0.3 0.3 0.7 -0.3 0.4 -0.6 -0.8 -0.2 -0.6 -0.7 0.4
Exposure to tobacco smoke at home 0.7 0.8 2.1 0.2 1.5 -1.5 -0.8 0.0 -0.5 -0.4 1.0
Breastfed as a baby 0.2 0.3 0.5 0.5 0.7 -0.6 -0.1 -0.7 -0.6 -0.2 0.4
Tense / ‘highly strung’ 2.2 3.7 8.4 0.7 -0.5 -0.7 2.9 1.0 2.2 2.4 -2.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 2.1 1.4 0.7 0.4 1.4 -0.3 0.2 1.0 -1.0
Hair/balding pattern: Pattern 4 0.3 0.8 2.1 0.8 -1.0 0.4 0.6 1.4 1.0 0.7 -0.6
Birth weight of first child 0.8 1.5 3.5 -0.6 1.1 -0.4 -1.5 -1.8 -1.9 -1.1 0.6
Peak expiratory flow (PEF) 0.1 0.3 1.0 1.0 0.3 -0.6 0.3 0.1 0.1 0.6 -0.5
Pulse wave reflection index 0.3 0.4 1.1 -0.8 -0.3 0.7 -0.6 -0.2 0.0 -0.6 1.0
Ever highly irritable/argumentative for 2 days 1.0 1.2 4.1 1.0 -2.0 -1.6 0.8 -0.2 0.8 0.5 -0.9
Loud music exposure frequency 0.8 0.9 3.1 1.8 0.4 1.2 0.5 -0.8 0.0 0.5 -1.1
Qualifications: O levels/GCSEs or equivalent 1.1 1.8 5.2 0.8 -0.9 1.3 1.3 2.3 1.6 1.2 -0.7
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 0.8 0.8 -0.9 -0.5 0.1 -0.5 0.1 0.1 -0.5
Blood clot in the leg (DVT) 0.4 0.6 1.5 -0.1 -0.8 -0.4 1.2 -0.1 0.9 0.9 -0.9
Medication: Paracetamol 1.0 1.7 9.6 1.7 0.5 3.1 -0.2 0.4 -0.1 0.6 0.2
Headache pain in last month 0.4 0.6 2.1 -0.2 0.7 1.5 -0.3 -0.4 -0.9 -0.5 1.1
Medication for cholesterol, blood pressure or diabetes 0.7 1.2 3.2 -0.3 -0.2 0.4 1.1 1.0 1.6 1.3 -1.8
Glaucoma (self-reported) 0.5 0.6 1.5 1.2 -0.9 -0.4 0.5 0.5 0.6 0.7 -0.8
Gout (self-reported) 1.6 2.1 4.0 1.4 1.3 0.1 -2.0 -1.2 -1.7 -1.4 1.8
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.2 0.3 1.5 0.9 -1.0 -1.2 -1.2 -0.7 0.9
Medication: Amlodipine 1.8 2.6 6.0 -0.5 1.0 -0.4 -1.8 -1.2 -2.3 -1.8 2.4
Medication: Ventolin 100micrograms inhaler 0.5 0.7 3.0 1.7 0.4 -0.4 0.8 0.9 0.1 0.7 -0.4
Birth weight 0.3 0.6 1.3 -0.9 -0.9 -1.1 -0.3 -0.4 -0.1 -1.1 0.7
Chronic bronchitis/emphysema (mother) 2.2 2.6 4.1 0.2 1.9 0.7 -1.4 -2.0 -2.0 -1.8 1.9
High blood pressure (siblings) 0.5 0.7 1.9 1.1 0.1 -0.2 1.4 0.1 0.7 0.8 -0.9
Forced vital capacity (FVC), Best measure 0.3 1.1 2.7 -0.5 1.6 -0.5 -1.2 0.5 -1.1 -0.6 1.6
Body fat percentage 0.3 1.0 2.8 1.7 -0.9 -1.0 -0.6 -1.3 -0.6 -0.9 0.2
Leg fat percentage (right) 0.3 0.9 2.9 1.7 -1.6 -0.6 0.4 -0.2 0.6 0.4 -0.9
Arm fat-free mass (right) 0.4 2.1 4.5 -2.1 -2.0 -0.1 -1.9 -0.8 -0.6 -1.7 0.8
Exposure to tobacco smoke outside home 0.2 0.3 0.9 0.4 0.9 0.1 0.2 0.8 0.2 0.8 -0.1
Comparative body size at age 10 0.6 1.6 8.5 0.5 -2.9 -1.5 0.5 -0.2 0.9 -0.0 -0.9
Number of full brothers 0.8 1.0 2.7 1.6 -0.6 0.8 1.3 0.7 0.8 0.8 -1.0
Worry too long after embarrassment 0.3 0.5 1.4 0.5 1.2 0.1 0.1 -1.1 -0.7 0.3 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 3.6 4.7 9.4 3.0 -1.6 -0.3 3.1 0.2 2.0 2.1 -2.8
Wheeze or whistling in the chest in last year 0.1 0.3 1.6 0.2 -0.4 -1.2 -0.1 0.4 0.1 0.2 -0.3
Number of children fathered 1.0 1.1 2.2 0.3 -1.5 0.3 1.2 0.9 1.4 0.8 -1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 0.9 -0.5 -0.9 -0.7 0.7 -0.0 0.8 -0.3 -0.5
Age at first live birth 1.1 1.9 4.0 0.4 -0.3 -1.9 2.0 -0.4 1.1 1.6 -1.8
Pulse wave peak to peak time 0.3 0.4 1.9 -1.4 -0.3 -0.6 0.1 0.5 0.1 -0.0 -0.4
Health satisfaction 0.6 0.8 2.4 1.3 0.8 -1.6 0.5 -0.1 -0.3 0.8 -0.8
Shortness of breath walking on level ground 1.1 1.3 6.3 0.4 -2.5 0.9 1.1 -0.2 0.8 -0.0 -1.0
Qualifications: College or University degree 0.5 1.5 3.1 1.3 0.4 -1.0 1.6 0.9 1.0 1.8 -1.3
Eye problems/disorders: None of the above 0.7 0.9 1.9 -0.3 0.8 1.1 -1.0 -0.6 -1.4 -0.8 1.0
Mouth/teeth dental problems: Loose teeth 0.4 0.5 2.0 1.4 0.2 1.0 -0.1 -0.2 -0.3 -0.5 0.7
Emphysema/chronic bronchitis 0.1 0.1 0.6 0.1 -0.8 -0.2 -0.2 0.0 -0.1 -0.3 -0.3
Medication for pain relief, constipation, heartburn 0.4 0.6 1.3 -0.5 -0.6 -1.1 1.2 0.1 1.1 0.3 -0.8
Neck or shoulder pain in last month 0.6 0.9 2.7 1.6 0.1 -0.3 1.1 0.6 0.5 0.9 -1.3
Medication: Blood pressure 1.6 2.7 6.2 -1.0 0.3 -0.7 -1.6 -1.6 -2.1 -2.2 2.5
Angina (self-reported) 0.2 0.3 1.0 -0.1 -0.3 0.1 -1.0 -0.3 -0.5 -1.0 0.4
Migraine (self-reported) 0.4 0.5 1.4 0.6 -0.3 0.7 0.7 0.1 0.4 0.8 -1.2
Medication: Ibuprofen 0.4 0.5 1.5 -0.3 0.2 1.2 0.5 1.0 0.5 0.7 -0.2
Medication: Allopurinol 0.4 0.5 2.1 1.0 -0.1 0.3 -1.4 -0.4 -0.6 -0.3 0.7
Medication: Omeprazole 0.4 0.5 1.5 1.1 -0.2 -1.2 -0.2 -0.7 -0.6 -0.2 0.2
Medication: Seretide 50 evohaler 2.0 2.3 4.2 0.8 -0.6 -1.2 2.0 1.4 1.4 1.9 -2.0
Mean time to correctly identify matches 0.4 0.8 2.4 0.4 -1.4 -0.3 0.3 1.6 1.2 0.5 -0.5
Heart disease (mother) 0.5 0.7 4.5 0.4 0.1 -2.1 0.5 -0.3 0.1 0.3 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.0 2.4 6.4 -0.7 -2.5 -0.5 2.1 0.9 2.0 0.8 -1.5
Whole body fat mass 0.3 1.1 1.9 0.7 -1.1 -1.1 -1.1 -1.3 -0.9 -1.4 0.6
Leg fat mass (right) 0.2 0.8 2.2 0.6 -1.5 -0.9 -0.8 -1.1 -0.4 -1.0 0.1
Arm predicted mass (right) 0.5 2.7 5.2 -2.2 -1.9 -0.0 -2.3 -1.3 -1.1 -2.0 1.1
Pulse rate, automated reading 0.1 0.4 2.2 1.5 0.2 -0.1 0.3 0.3 0.2 0.5 -0.7
Alcohol intake frequency. 0.1 0.3 0.8 0.9 0.7 0.6 -0.0 -0.4 -0.4 -0.1 0.1
Comparative height size at age 10 0.3 1.7 4.7 -1.7 0.7 -0.0 -2.2 0.2 -0.9 -1.4 1.8
Number of full sisters 0.5 0.6 2.2 -0.7 -1.5 0.0 -0.5 -1.1 -0.3 -0.5 -0.6
Suffer from ‘nerves’ 3.3 5.2 10.7 0.9 0.0 -3.1 3.3 1.9 2.4 2.4 -2.4
Overall health rating 0.9 1.9 3.1 1.7 1.1 -1.8 -0.9 -1.1 -1.7 -1.2 1.1
Chest pain or discomfort 1.0 1.4 2.8 0.8 -0.9 -0.5 1.4 1.1 1.6 1.2 -1.7
Had major operations 0.9 1.0 1.8 -0.9 1.2 -0.5 -1.3 -0.5 -1.3 -0.7 1.2
Age at last live birth 0.7 1.0 2.2 1.5 0.3 -1.1 1.3 -0.5 0.3 1.2 -0.9
Family relationship satisfaction 0.8 0.9 2.6 0.3 0.2 0.6 0.9 1.3 0.9 1.6 -1.1
Leg pain on walking 1.8 2.3 4.0 1.5 0.2 -2.0 -1.1 -1.9 -1.6 -1.4 1.6
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 0.6 0.4 -0.8 0.7 0.8 -0.5 0.0 -0.4 0.1
Commuting to job workplace: Car/motor vehicle 0.7 0.8 3.1 -1.7 -0.8 -1.1 -0.1 0.8 0.8 0.2 -0.4
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 3.3 -1.2 1.0 1.8 -0.1 1.4 0.2 1.1 -0.1
Medication: Aspirin 2.8 3.7 5.9 -0.3 0.5 -2.1 -2.4 -1.8 -2.4 -2.2 2.2
Supplements: Vitamin C 0.4 0.4 1.5 0.6 0.0 -1.2 0.7 -0.3 0.1 0.6 -0.8
Knee pain experienced in last month 0.8 1.2 3.6 1.9 0.7 -1.2 -0.7 -1.4 -0.9 -0.7 0.5
Hypertension (Self-reported) 1.0 2.7 6.5 0.5 0.2 -0.3 -1.4 -1.9 -2.1 -2.2 2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.9 4.0 0.8 0.4 -2.0 0.7 -0.4 -0.0 0.7 -1.0
Illnesses of father: Heart disease 2.9 4.0 9.6 0.3 3.1 -0.1 -2.1 -2.4 -2.6 -1.4 1.8
Illnesses of siblings: Diabetes 1.0 1.2 2.3 -0.8 1.4 -1.5 -0.9 -0.9 -0.9 -1.1 1.1
Smoking status: Previous 2.2 3.3 6.8 0.5 -1.0 0.8 2.5 1.2 2.3 2.6 -2.2
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 1.5 0.2 0.5 -0.7 -1.2 -0.0 -0.7 -0.1 0.8
Whole body fat-free mass 0.4 2.6 5.3 -2.0 -1.4 -0.5 -2.3 -1.1 -1.2 -2.1 1.4
Leg fat-free mass (right) 0.7 3.7 8.0 -1.1 -1.1 -0.6 -2.7 -2.0 -2.0 -2.8 1.8
Arm fat percentage (left) 0.2 1.0 4.0 2.0 -1.0 -1.0 -0.1 -1.2 -0.3 -0.6 -0.2
Average weekly red wine intake 0.2 0.3 0.8 0.2 0.7 -0.5 -0.3 -0.6 -0.9 -0.4 0.4
Handedness (chirality/laterality): Left-handed 1.5 1.7 3.8 -0.2 -1.2 -0.1 1.4 1.9 2.0 1.4 -1.0
Mood swings 0.3 0.5 2.1 1.4 0.5 -0.2 0.6 0.3 0.4 0.7 -0.8
Loneliness, isolation 0.6 0.8 2.0 0.7 1.4 -1.0 -0.7 -0.8 -1.2 -0.2 0.7
Long-standing illness, disability or infirmity 0.9 1.3 9.1 0.8 0.6 -3.0 0.2 -0.3 -0.5 0.0 0.3
Ever had bowel cancer screening 0.6 0.7 3.6 0.2 0.8 -1.9 0.2 0.8 0.3 0.8 -0.2
Diabetes diagnosed by doctor 0.8 1.3 2.5 1.4 0.9 -0.9 -1.2 -1.3 -1.6 -0.7 0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.2 0.5 -0.1 0.9 -1.1 0.7 -0.3 -0.1 0.6
Friendships satisfaction 0.4 0.5 1.3 -0.2 0.8 0.0 -1.2 0.0 -0.9 -0.4 1.0
Qualifications: nursing, teaching 0.6 1.0 1.9 0.4 -0.4 1.4 1.2 1.2 1.0 1.0 -0.8
Commuting to job workplace: Walk 0.5 0.6 2.6 1.6 0.4 -1.3 0.3 -0.4 -0.3 -0.2 0.0
Eye problems/disorders: Cataract 0.6 0.7 1.6 -0.2 -1.2 0.3 0.9 0.6 1.3 0.6 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 1.7 0.6 -0.5 -1.3 -0.5 0.4 -0.2 -0.2 0.6
Medication for cholesterol 2.1 3.1 9.1 1.0 -1.1 -0.4 2.4 0.4 1.3 2.5 -3.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.3 1.6 6.2 -2.5 -0.1 -1.7 -0.8 -0.9 -0.5 -1.2 0.6
Back pain experienced in last month 1.1 1.6 3.2 1.1 -0.9 -0.2 1.0 1.2 1.3 1.8 -1.7
Mineral and other dietary supplements 2.4 3.2 8.6 0.5 -0.9 -2.9 1.3 2.2 1.6 1.9 -1.8
Breast cancer (self-reported) 0.9 1.0 4.2 2.1 0.9 -0.3 1.0 -0.8 0.2 1.1 -0.6
Asthma (self-reported) 0.6 1.1 2.6 1.0 -0.9 -0.3 1.2 1.6 1.0 1.1 -0.8
Osteoporosis (self-reported) 1.3 1.6 3.5 0.5 -1.5 -1.9 1.6 0.6 1.3 0.8 -1.3
Osteoarthritis (self-reported) 1.2 1.6 3.7 0.3 -1.0 -0.7 -1.9 -1.4 -1.3 -1.7 1.1
Medication: Aspirin 3.0 3.9 7.4 -0.4 0.9 -1.4 -2.6 -1.9 -2.7 -2.2 2.4
Medication: Gliclazide 0.5 0.6 1.0 0.2 -0.5 -0.8 0.4 0.8 1.0 0.9 -1.0
Illnesses of father: None of the above (group 1) 1.7 2.1 3.4 0.2 -1.6 -0.2 1.5 1.8 1.9 1.5 -1.7
Smoking status: Current 0.6 1.0 2.2 -1.5 -0.9 -0.8 -1.2 -0.6 -0.7 -1.3 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.7 0.6 0.6 -0.2 0.2 0.8 0.3 0.8 -0.1
Whole body water mass 0.5 2.6 5.5 -1.9 -1.4 -0.4 -2.3 -1.2 -1.3 -2.1 1.4
Leg predicted mass (right) 0.7 3.7 8.0 -1.0 -1.1 -0.5 -2.7 -2.1 -2.1 -2.8 1.9
Arm fat mass (left) 0.2 0.8 2.1 0.9 -1.5 -1.2 -0.5 -1.0 -0.3 -0.8 -0.1
Number of self-reported non-cancer illnesses 1.8 3.1 6.0 1.4 -0.0 -1.2 -1.6 -1.7 -2.2 -2.5 2.2
Average weekly champagne plus white wine intake 1.7 2.3 6.2 2.4 -0.2 -0.0 0.7 2.5 1.4 1.9 -0.7
Miserableness 0.6 1.1 3.2 0.0 0.7 1.1 0.6 1.8 0.9 1.5 -0.6
Guilty feelings 0.2 0.3 0.5 -0.7 0.5 -0.6 -0.3 -0.6 -0.5 0.2 -0.3
Wears glasses or contact lenses 0.4 0.5 2.1 1.5 -0.9 -0.2 0.8 -0.2 0.2 -0.1 -0.4
Ever taken oral contraceptive pill 0.9 1.0 2.7 1.0 1.7 1.1 0.4 1.4 -0.1 1.1 0.1
Hearing aid user 0.8 0.9 2.4 0.3 0.4 -1.4 -1.3 -0.0 -0.6 -0.8 1.5
Mother’s age at death 2.2 2.7 5.4 0.4 1.9 -0.1 -1.9 -1.2 -1.8 -2.1 2.3
Financial situation satisfaction 0.7 0.8 2.2 1.1 -1.5 -0.7 1.1 -0.0 0.7 0.1 -1.0
Tinnitus: Yes, now most or all of the time 1.2 1.4 3.2 -0.1 -0.9 -1.8 -1.0 -1.4 -0.7 -1.6 1.3
Commuting to job workplace: Public transport 0.5 0.7 1.7 1.0 1.3 1.2 -0.2 -0.6 -0.6 -0.1 0.5
Eye problems/disorders: Glaucoma 0.3 0.4 1.0 0.3 -1.0 -0.1 0.4 0.6 0.7 0.6 -0.8
Medication: Blood pressure 0.3 0.6 2.0 0.8 0.4 -0.3 -0.9 -0.0 -0.4 -0.9 1.4
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.7 0.1 -0.3 0.2 0.3 -0.1 0.1 0.4 -0.9
Supplements: Fish oil (including cod liver oil) 4.7 6.1 9.0 -1.4 1.5 1.9 -3.0 -2.5 -2.9 -3.0 2.8
High cholesterol (Self-reported) 0.4 0.7 1.3 1.1 0.7 0.2 -0.8 -0.8 -0.9 -0.7 1.1
Medication: Bendroflumethiazide 2.0 3.0 7.8 0.8 0.6 0.4 -2.0 -1.4 -1.8 -2.3 2.8
Medication: Paracetamol 0.9 1.4 9.0 0.8 0.2 3.0 -0.2 0.7 0.0 0.9 0.1
Medication: Lisinopril 1.0 1.4 3.2 -1.3 -0.1 -1.8 -1.0 -0.6 -0.8 -1.3 1.5
Medication: Atorvastatin 0.7 0.9 2.3 -0.9 0.4 -0.9 -0.8 -0.3 -0.7 -1.4 1.5
Illnesses of father: High blood pressure 0.2 0.2 1.0 -0.3 -0.3 1.0 -0.5 0.2 0.1 -0.2 0.3
Alcohol drinker status: Never 1.0 1.2 3.5 -0.0 -0.3 0.6 -1.0 -1.0 -1.2 -1.9 1.4
Ever smoked 0.5 0.9 2.6 -1.1 -1.6 -0.5 0.8 0.1 1.1 0.7 -1.0
Basal metabolic rate 0.4 2.1 4.3 -1.5 -1.4 -0.6 -2.1 -1.1 -1.2 -1.9 1.2
Leg fat percentage (left) 0.2 0.7 2.4 1.5 -1.4 -0.8 -0.1 -0.7 0.1 -0.3 -0.4
Arm fat-free mass (left) 0.4 2.0 4.2 -2.0 -2.0 -0.4 -1.8 -0.8 -0.6 -1.7 0.9
Number of operations (self-reported) 2.2 3.2 7.6 -1.6 1.0 -0.3 -1.5 -2.7 -2.5 -2.1 1.4
Average weekly beer plus cider intake 1.0 1.5 2.8 1.6 -1.7 -0.6 1.1 -1.2 0.3 0.8 -1.6
Irritability 0.7 1.1 4.0 2.0 1.0 -0.0 0.3 1.0 0.1 1.4 -0.9
Risk taking 0.1 0.1 0.2 -0.3 -0.1 0.5 0.2 -0.4 -0.3 -0.0 -0.4
Ever had prostate specific antigen (PSA) test 0.4 0.4 3.0 1.7 -0.0 -0.1 0.0 -0.3 -0.4 0.2 0.3
Fractured/broken bones in last 5 years 0.5 0.6 2.0 0.5 -0.8 -1.4 0.3 -1.2 -0.1 -0.3 -0.4
Age started oral contraceptive pill 0.3 0.4 2.4 1.6 -0.1 0.8 0.1 -0.2 0.1 -0.1 0.4
Diastolic blood pressure, automated reading 0.1 0.4 1.4 0.3 -1.2 -0.1 0.8 -0.3 0.5 0.3 -0.7
Ever depressed for a whole week 0.4 0.5 1.8 -1.2 0.1 -1.4 -0.0 -0.7 -0.3 -0.4 -0.1
Unable to work because of sickness or disability 0.4 0.6 1.8 1.4 1.0 -1.0 -0.3 -0.5 -0.7 0.2 0.2
Commuting to job workplace: Cycle 0.5 0.6 1.5 -0.8 -1.2 -0.8 0.7 -0.7 0.7 -0.3 -0.4
Myopia 1.6 2.3 5.0 1.7 0.9 -1.2 -1.2 -2.2 -2.1 -1.1 1.2
Vascular/heart problems diagnosed by doctor 2.0 5.5 11.4 0.7 -0.4 0.7 2.7 2.3 2.8 3.3 -3.4
Cholesterol lowering medication 1.2 1.8 4.3 -0.5 0.5 -0.3 -2.1 -0.9 -1.2 -2.0 1.8
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.6 1.6 0.0 -1.0 0.1 -0.2 -0.3 0.5 -0.1
Pain experienced in last month 1.4 2.4 5.4 -2.3 0.1 -0.1 -2.0 -0.6 -1.3 -1.9 1.9
Supplements: Calcium 3.5 3.9 5.7 0.7 2.1 1.3 -1.9 -2.3 -2.4 -2.2 2.2
Basal cell carcinoma (self-reported) 0.8 1.0 4.1 1.1 -0.6 2.0 0.7 0.7 0.8 0.7 -0.2
Heart attack/myocardial infarction (self-reported) 1.3 1.7 3.6 -0.4 1.0 0.1 -1.3 -1.6 -1.9 -1.6 1.4
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.7 -0.1 -1.0 -0.6 1.3 -0.3 0.9 0.7 -0.8
Heart disease (siblings) 0.2 0.3 0.7 0.8 -0.1 0.3 -0.6 -0.3 -0.5 -0.6 0.3
Alcohol drinker status: Previous 1.4 1.6 3.5 0.6 -0.5 0.8 1.9 0.7 1.2 1.9 -1.6
Pack years of smoking 1.7 2.6 6.0 -0.1 0.4 -0.2 -2.1 -1.7 -1.8 -2.5 1.9
Impedance of whole body 0.4 2.0 9.7 1.7 3.1 0.2 1.2 0.7 0.2 1.3 -0.1
Leg fat mass (left) 0.3 1.0 2.4 0.6 -1.5 -1.0 -1.0 -1.2 -0.6 -1.2 0.3
Arm predicted mass (left) 0.4 2.1 4.1 -2.0 -2.0 -0.3 -1.9 -0.8 -0.7 -1.7 0.9