Best TWAS P=3.74e-12 · Best GWAS P=2.09e-08 conditioned to 0.982
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | DEF6 | 0.03 | 0.02 | bslmm | 420 | 0.02 | 7.2e-07 | -5.4 | 5.9 | 4.4e-09 | -0.73 | 0.02 | 0.98 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ZNF76 | 0.04 | 0.00 | blup | 424 | 0.02 | 2.1e-03 | -5.4 | 7.0 | 3.7e-12 | -0.81 | 0.02 | 0.96 | TRUE |
| 3 | YFS | Blood | ZNF76 | 0.05 | 0.08 | lasso | 4 | 0.07 | 6.7e-23 | -5.5 | 5.4 | 5.2e-08 | -0.87 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DEF6 | 0.04 | 0.01 | blup | 50 | 0.03 | 6.2e-04 | -5.3 | 5.3 | 9.1e-08 | -0.77 | 0.01 | 0.95 | FALSE |