Best TWAS P=3.25e-11 · Best GWAS P=4.85e-18 conditioned to 2.85e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ENTPD6 | 0.06 | 0.01 | lasso | 2 | 0.02 | 0.00010 | 1.2 | 5.9 | 3.3e-09 | -0.64 | 0.00 | 0.71 | FALSE |
2 | The Cancer Genome Atlas | Esophageal Carcinoma | ACSS1 | 0.18 | 0.04 | enet | 4 | 0.07 | 0.00265 | -4.7 | -5.7 | 1.0e-08 | 0.34 | 0.02 | 0.20 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ENTPD6 | 0.14 | 0.00 | enet | 19 | 0.03 | 0.00045 | -1.5 | 6.6 | 3.2e-11 | -0.46 | 0.10 | 0.60 | TRUE |