Hub : Genes

BBS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1190 0.0400 8.1e-11 0.101 0.079 0.090 0.09 0.108 2.7e-12 6.8e-10 4.2e-11 4.4e-11 5.1e-13
2 GTEx Testis 0.0700 0.0340 4.8e-03 0.098 NA 0.055 NA 0.067 4.2e-05 NA 1.9e-03 NA 6.3e-04
3 YFS Blood 0.0219 0.0091 5.6e-07 0.016 0.020 0.021 0.02 0.021 4.7e-06 2.7e-07 1.8e-07 3.2e-07 1.4e-07
4 TCGA Kidney Renal Clear Cell Carcinoma 0.0292 0.0216 2.3e-03 0.009 0.019 0.022 NA 0.017 2.7e-02 2.6e-03 1.5e-03 NA 4.3e-03
5 TCGA Brain Lower Grade Glioma 0.1441 0.0607 5.4e-11 0.095 0.098 0.086 NA 0.093 6.6e-11 3.0e-11 4.9e-10 NA 1.1e-10
6 TCGA Lung Adenocarcinoma 0.0335 0.0201 1.1e-03 0.009 0.020 0.023 NA 0.021 2.7e-02 1.7e-03 9.9e-04 NA 1.6e-03
7 TCGA Lung Squamous Cell Carcinoma 0.0235 0.0157 1.9e-03 0.019 0.022 0.019 NA 0.021 2.7e-03 1.3e-03 2.6e-03 NA 1.8e-03
8 TCGA Pheochromocytoma and Paraganglioma 0.1420 0.0740 9.5e-06 0.154 0.156 0.153 NA 0.170 1.0e-06 8.9e-07 1.2e-06 NA 2.7e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 8.2 12.9 17.0 3.3 -4.1 3.7 3.4 3.2 4.0 4.0 2.7
Bipolar Disorder or Schizophrenia 9.2 22.5 33.6 3.9 -5.8 5.0 4.5 4.3 5.1 5.4 3.6
Depressed Affect (Nagel 2018) 0.5 1.0 5.3 0.6 -2.3 0.3 0.7 0.3 0.1 0.7 1.1
Depression (Nagel 2018) 0.5 0.7 1.5 -1.2 -1.2 -0.8 -0.6 -0.8 0.4 -0.3 -0.8
Intelligence (Savage-Jansen 2018) 2.4 7.4 9.9 -2.8 2.4 -2.9 -2.9 -3.2 -1.2 -2.9 -2.9
Neuroticism (Nagel 2018) 0.5 1.2 6.8 -0.1 -2.6 0.2 0.4 0.3 1.3 0.8 0.4
Schizophrenia (2018) 5.0 10.3 16.9 2.4 -4.1 3.4 3.0 2.9 3.3 3.7 2.4
Schizophrenia vs Biploar Disorder 1.3 1.7 4.9 -0.9 1.1 -1.5 -0.7 -1.4 -2.2 -1.5 -0.3
Worry (Nagel 2018) 0.5 1.0 2.3 -1.5 -0.8 -1.0 -0.7 -0.8 0.7 -0.5 -1.3
Alzheimer’s Disease (in mother) 0.8 0.9 2.1 -1.1 0.6 -1.1 -0.7 -1.4 -0.1 -0.8 -1.2
Alzheimer’s Disease (in father) 0.4 0.4 1.5 -0.3 1.2 -0.4 -0.8 0.0 -0.9 -0.6 0.1
Alzheimer’s Disease (including proxy) 0.2 0.3 0.6 -0.6 0.8 -0.4 -0.6 -0.3 -0.2 -0.3 -0.6
Crohns Disease (2017) 0.4 0.8 1.6 -1.3 -0.2 -0.8 -1.0 -1.0 -0.5 -0.8 -1.0
Irritable Bowel Disease (IBD) 0.3 0.8 3.7 0.7 -1.9 0.5 1.0 0.0 0.3 0.8 0.7
Ulcerative Colitis (UC) 2.0 3.8 7.8 2.1 -2.8 1.5 2.5 1.0 0.9 2.0 2.0
Major Depression (MDD) 0.2 0.3 1.0 -0.5 -1.0 -0.4 -0.6 -0.4 -0.3 -0.3 0.1
Reaction Time 0.6 1.1 5.5 1.0 0.9 -0.0 0.6 0.0 -2.4 -0.2 0.9
Verbal and Numeric Reasoning (VNR) 1.3 3.0 4.5 -1.8 1.2 -1.9 -1.9 -2.1 -0.4 -1.8 -2.1
Breast Cancer 1.8 4.4 12.5 -3.0 -0.2 -1.3 -1.8 -1.2 2.5 -1.0 -3.5
Ovarian Cancer 1.5 2.0 2.7 1.4 -1.4 1.6 1.6 1.4 1.2 1.6 1.1
Prostate Cancer 0.1 0.1 0.6 -0.3 -0.8 0.2 0.5 0.0 0.3 0.1 -0.2
Age at First Birth 0.8 1.1 5.1 0.1 2.2 -0.2 -0.5 0.3 -1.7 -0.6 0.7
Bipolar Disorder (2011) 8.7 8.4 18.7 1.4 -3.7 3.0 2.1 2.9 4.3 3.2 1.2
Body Mass Index (BMI) (2010) 0.0 0.0 0.1 0.2 0.1 -0.1 -0.1 -0.1 -0.3 -0.0 0.3
Coronary Artery Disease (CAD) 0.1 0.1 0.6 -0.4 -0.8 -0.1 0.2 -0.2 0.2 -0.0 -0.5
Crohns Disease (2012) 0.4 0.6 1.3 -1.1 -0.9 -0.2 -0.8 -0.3 1.1 0.0 -1.0
Mean Putamen Volume 0.4 0.4 1.1 -0.4 1.0 -0.6 -0.1 -0.5 -1.0 -0.7 -0.2
Fasting Glucose 0.3 0.4 1.2 -0.4 0.2 -0.4 -1.1 -0.8 0.0 -0.6 -0.8
HbA1C 0.8 0.9 1.6 -1.2 1.0 -1.0 -0.9 -0.8 -0.2 -0.9 -1.0
HDL Cholesterol 0.5 0.8 1.5 -0.4 1.0 -1.0 -0.2 -1.0 -1.2 -0.9 -0.7
LDL Cholesterol 3.7 5.9 11.8 2.8 -1.5 2.4 2.8 2.4 0.4 2.3 3.4
Lupus 0.9 1.4 2.7 -1.6 -0.0 -1.2 -1.4 -1.2 0.1 -1.1 -1.5
Neuroticism (2016) 0.4 0.6 2.1 -1.4 -0.6 -0.6 -0.9 -0.3 0.2 -0.6 -0.9
Primary Biliary Cirrhosis 1.9 2.8 6.7 2.6 -0.4 1.4 2.0 1.1 -0.3 1.4 2.4
Rheumatoid Arthritis 0.7 0.9 2.9 -0.5 1.1 -0.9 -0.5 -0.8 -1.7 -1.0 -0.5
Schizophrenia (2014) 3.8 8.3 13.7 2.4 -3.7 3.0 2.8 2.5 2.8 3.2 2.4
Triglycerides 0.3 0.5 1.8 0.5 0.2 0.2 0.4 0.5 -1.2 0.2 1.3
Type 2 Diabetes (T2D) (2012) 0.2 0.2 1.0 0.5 0.2 0.1 0.2 0.4 -0.5 0.2 1.0
Ulcerative Colitis 4.9 7.1 10.9 2.6 -3.3 2.6 3.0 2.2 2.0 2.9 2.5
Blood Eosinophil Count 0.2 1.5 5.2 -2.3 0.7 -0.3 -2.0 0.5 -0.2 -0.7 -1.2
Blood Platelet Count 0.1 1.7 3.6 -1.4 -1.9 -0.7 -0.4 -1.4 1.9 -0.1 -1.2
Blood Red Count 6.6 64.0 82.4 7.3 -8.6 8.7 8.3 7.9 8.0 9.1 5.4
Blood White Count 0.2 1.3 4.2 -1.6 -1.2 -0.4 -0.4 -0.5 2.1 0.1 -1.2
Heel T-Score 1.3 10.3 17.7 -3.5 3.2 -2.9 -4.2 -2.4 -3.1 -3.6 -2.2
BMI 2.3 13.6 24.5 3.4 -5.0 3.2 3.8 2.7 3.6 3.9 3.6
Height 4.6 89.4 134.6 -9.5 11.6 -10.1 -9.7 -9.7 -6.6 -10.1 -7.5
Waist Hip Ratio (WHR) 0.9 3.8 7.2 0.4 -2.2 2.4 0.7 2.6 2.7 2.3 0.3
Systolic Blood Pressure 0.1 0.4 0.9 0.7 0.4 0.7 -0.7 1.0 -0.5 0.2 -0.4
Smoking Status 1.4 3.4 7.0 1.0 -1.8 2.2 1.4 2.6 2.0 2.1 0.8
Allergy or Eczema 2.3 6.0 14.9 1.0 -3.1 2.6 1.7 2.5 3.9 2.7 0.5
Cardiovascular Disease 1.8 5.9 9.7 1.3 -3.1 3.0 1.3 2.9 2.7 2.8 1.3
Hypothyroidism (self reported) 0.1 0.3 0.8 0.9 -0.1 0.3 0.4 0.4 -0.8 0.2 0.7
Respiratory disease 5.3 11.7 17.0 4.1 -2.3 3.5 4.1 3.1 2.0 3.9 3.7
Type 2 Diabetes (T2D) (2018) 1.2 2.3 4.2 1.3 -1.5 1.7 1.2 2.0 1.1 1.6 1.5
Lung FEV1/FVC ratio 0.5 2.3 11.5 -0.1 3.4 -0.7 -0.8 -0.3 -2.0 -1.3 0.2
Lung FVC 1.3 6.7 19.1 -3.2 -1.4 -2.1 -0.6 -3.0 2.7 -1.1 -4.4
Neuroticism 0.4 0.9 2.8 0.3 -1.7 0.5 0.7 0.8 1.2 0.9 0.7
Chronotype (morning person) 4.7 10.9 23.6 -1.2 4.7 -3.3 -2.1 -3.2 -4.9 -3.6 -1.2
Hair Pigment 0.2 6.1 18.1 -2.6 -0.8 -3.1 -0.7 -4.2 1.3 -1.7 -2.9
Tanning 0.1 0.7 1.9 1.4 -0.6 0.4 1.0 0.4 -0.7 0.4 1.3
Hand grip strength (left) 5.0 13.1 17.9 -3.6 3.5 -4.2 -3.2 -4.1 -2.4 -4.1 -3.4
Number of treatments/medications taken 4.6 8.3 13.2 2.7 -3.6 3.0 2.4 2.7 2.6 3.3 2.5
Average weekly spirits intake 0.5 0.7 1.6 -0.8 0.4 -1.1 -0.8 -1.3 -0.0 -0.8 -0.8
Sensitivity / hurt feelings 0.1 0.1 0.4 -0.1 -0.6 0.2 0.1 0.3 0.6 0.3 0.2
Frequency of depressed mood in last 2 weeks 0.1 0.1 0.3 0.1 -0.1 0.1 0.4 0.2 -0.5 0.2 0.5
Hearing difficulty/problems: Yes 3.6 5.5 11.4 1.4 -3.4 2.2 2.2 2.0 3.0 2.5 1.4
Relative age of first facial hair 0.9 1.9 3.0 1.5 -1.7 1.3 1.5 1.0 1.1 1.5 1.2
Other serious medical condition/disability diagnosed by doctor 3.8 4.9 11.9 1.5 -3.4 2.0 1.9 1.7 2.5 2.4 1.6
Ever used hormone-replacement therapy (HRT) 0.5 0.7 1.8 1.3 -0.3 0.7 0.8 0.6 -0.3 0.7 1.2
Ever had hysterectomy (womb removed) 0.5 0.5 1.5 1.2 -0.3 0.4 1.0 0.1 -0.7 0.4 0.9
Systolic blood pressure, automated reading 0.0 0.1 0.5 0.7 -0.2 0.4 -0.2 0.2 -0.1 0.3 -0.2
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.4 -0.5 -0.3 -0.3 -0.4 -0.1 0.3 -0.2 -0.6
Angina 0.7 1.0 2.0 -1.4 -0.6 -1.0 -1.0 -1.0 0.3 -0.7 -1.4
Medication for hormone replacement therapy 0.1 0.1 0.4 0.0 -0.1 -0.1 -0.0 -0.2 0.6 0.1 -0.2
Vitamin and mineral supplements 1.0 1.4 3.8 1.4 1.1 0.0 1.0 -0.1 -1.7 0.2 2.0
Supplements: Zinc 0.1 0.1 0.4 0.4 -0.1 0.6 0.0 0.6 0.4 0.3 -0.1
Medication: Co-codamol 1.8 2.1 6.9 1.9 -1.2 0.7 1.7 0.1 -0.1 1.2 2.6
Medication: Metformin 0.3 0.5 1.7 0.0 -0.5 0.8 -0.1 1.3 0.5 0.6 0.6
Diabetes (father) 0.3 0.3 0.8 -0.8 0.3 -0.3 -0.9 -0.2 0.2 -0.4 -0.9
Diabetes (mother) 0.2 0.2 0.6 -0.5 -0.3 -0.4 -0.8 -0.2 0.1 -0.4 -0.8
Severe depression (siblings) 0.3 0.4 1.3 -0.4 -0.9 0.3 -0.1 0.2 1.1 0.5 -0.6
Pack years adult smoking proportion 1.0 1.5 4.3 1.6 -0.2 0.8 2.1 0.7 -0.1 1.2 1.6
Impedance of leg (right) 5.7 27.6 53.5 -3.7 7.3 -4.8 -4.5 -4.2 -7.1 -5.8 -2.7
Leg fat-free mass (left) 0.2 1.0 4.9 0.1 -1.2 0.1 0.5 -0.1 2.2 0.9 0.4
Trunk fat percentage 0.3 1.2 4.4 1.2 -1.1 0.8 0.7 0.7 0.5 1.0 2.1
Hand grip strength (right) 4.0 10.9 14.2 -3.0 3.8 -3.7 -3.2 -3.5 -2.8 -3.8 -2.4
Townsend deprivation index at recruitment 0.8 1.2 2.4 0.7 -1.6 1.1 0.8 1.3 0.9 1.1 0.9
Current tobacco smoking 2.1 3.4 6.0 2.5 -0.5 1.8 2.4 1.9 -0.4 1.6 2.4
Average weekly fortified wine intake 0.3 0.3 1.0 -0.4 -1.0 -0.5 -0.1 -0.8 0.4 -0.2 -0.3
Maternal smoking around birth 0.6 0.9 2.4 0.4 -1.6 0.9 0.8 0.9 1.1 1.0 0.3
Fed-up feelings 0.9 1.7 5.1 1.4 -0.8 0.6 1.0 0.7 -1.8 0.7 2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 1.7 0.5 -1.3 0.3 0.8 0.1 -0.2 0.5 0.9
Relative age voice broke 0.0 0.0 0.2 0.0 -0.4 0.0 0.2 0.0 0.1 0.1 -0.0
Taking other prescription medications 4.5 6.9 11.4 2.4 -3.4 2.7 2.2 2.5 2.0 2.9 2.7
Age when periods started (menarche) 0.6 1.3 2.9 1.4 -0.2 1.3 0.9 1.4 0.5 1.1 1.7
Bilateral oophorectomy (both ovaries removed) 1.1 1.2 3.0 1.7 -0.8 0.8 1.2 0.5 -0.7 0.8 1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.5 3.5 -1.4 0.5 -1.2 -1.9 -1.1 -1.0 -1.3 -1.0
Tinnitus: Yes, but not now, but have in the past 2.0 2.2 4.2 1.5 -1.3 1.2 2.0 1.1 1.3 1.6 1.5
Qualifications: CSEs or equivalent 2.5 3.3 5.8 -1.1 2.1 -2.0 -1.6 -1.8 -2.4 -2.1 -0.9
Serious illness, injury or assault to yourself 1.7 2.0 4.5 1.1 -1.6 1.3 1.5 1.5 -0.3 1.3 2.1
High blood pressure 0.5 1.5 3.0 0.3 -1.4 1.7 -0.2 1.7 1.5 1.4 0.4
Hayfever, allergic rhinitis or eczema 1.9 4.2 6.1 1.6 -2.0 2.2 1.9 2.2 2.5 2.3 1.4
Multivitamins +/- minerals 0.8 1.1 3.2 -1.1 -0.9 0.0 -1.1 0.2 1.4 -0.2 -1.8
Stomach or abdominal pain in last month 0.7 0.9 2.3 0.3 -1.5 0.8 0.5 0.9 1.3 0.9 0.5
Supplements: Glucosamine 2.2 2.9 7.7 -2.2 -0.1 -1.5 -1.4 -1.9 1.0 -1.2 -2.8
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 2.2 -1.3 -1.2 -0.5 -0.7 -0.7 1.0 -0.3 -1.5
Medication: Atenolol 1.3 1.6 3.0 -1.7 0.4 -1.1 -1.7 -1.1 0.0 -1.1 -1.7
Medication: Levothyroxine sodium 0.1 0.1 0.4 -0.0 -0.3 -0.5 -0.1 -0.4 -0.6 -0.4 0.2
Sitting height 1.1 7.7 9.4 -3.1 2.7 -3.0 -3.0 -2.8 -1.7 -3.0 -2.8
Chronic bronchitis/emphysema (father) 0.3 0.3 0.8 -0.7 -0.7 -0.3 -0.9 -0.3 0.4 -0.3 -0.5
High blood pressure (mother) 2.0 2.7 5.5 -1.9 0.8 -1.6 -2.3 -1.6 -0.0 -1.6 -2.1
Body mass index (BMI) 3.5 14.7 25.0 3.6 -5.0 3.5 3.7 3.1 3.6 4.2 3.7
Impedance of leg (left) 5.5 26.8 47.5 -4.0 6.9 -4.8 -4.7 -4.3 -6.6 -5.9 -2.9
Leg predicted mass (left) 0.2 0.9 4.6 0.1 -1.1 0.1 0.4 -0.2 2.1 0.8 0.4
Trunk fat mass 0.2 0.7 3.1 0.8 -0.8 0.4 0.6 0.3 0.7 0.8 1.8
Waist circumference 1.1 4.0 7.3 1.5 -2.7 1.7 1.6 1.5 2.4 2.2 2.0
Number of incorrect matches in round 1.7 2.8 4.9 -1.9 0.3 -1.9 -1.6 -2.0 -0.1 -1.8 -2.2
Past tobacco smoking 1.2 2.2 6.0 0.1 1.6 -1.7 -0.4 -1.9 -2.4 -1.6 0.3
Alcohol usually taken with meals 0.9 1.5 5.3 -1.6 0.4 -0.7 -1.2 -0.3 1.2 -0.7 -2.3
Nervous feelings 3.3 6.2 8.0 -2.5 2.7 -2.5 -2.7 -1.9 -2.4 -2.8 -2.1
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.2 0.2 -1.5 0.3 0.8 0.5 0.8 0.6 0.7
Hearing difficulty/problems with background noise 4.4 7.0 11.0 1.3 -3.3 2.9 2.1 3.1 3.2 3.0 1.5
Hair/balding pattern: Pattern 2 0.3 0.3 0.8 0.7 0.8 0.1 0.3 0.2 -0.9 0.1 0.7
Had menopause 0.1 0.1 0.3 -0.1 0.6 -0.1 -0.3 -0.2 -0.3 -0.2 -0.1
Had other major operations 0.0 0.1 0.2 -0.0 -0.4 -0.0 -0.1 -0.2 0.4 0.3 0.1
Forced vital capacity (FVC) 5.2 20.2 32.1 -5.2 3.2 -5.3 -3.8 -5.7 -1.1 -4.6 -5.2
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.2 4.7 -1.7 1.1 -1.4 -2.2 -1.2 -1.0 -1.6 -1.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 0.6 0.4 -0.0 0.4 0.7 0.7 0.1 0.5 0.8
Qualifications: None of the above 0.6 1.3 5.9 1.0 0.6 0.1 0.5 0.2 -2.4 0.0 1.6
Financial difficulties in last 2 years 2.8 3.8 4.7 2.1 -1.5 2.0 2.2 2.0 1.5 2.1 2.1
Mouth/teeth dental problems 0.2 0.3 1.0 0.7 1.0 0.1 0.4 0.0 -0.8 -0.0 0.5
Heart attack 2.6 3.3 5.7 -2.3 0.1 -1.9 -2.0 -1.9 -0.7 -1.8 -2.4
Allergy 6.3 14.6 19.6 -3.5 3.7 -4.1 -3.9 -3.7 -4.0 -4.4 -3.0
Pain all over the body in last month 0.7 0.8 2.4 0.9 -0.7 -0.0 1.4 -0.4 -0.3 0.5 1.5
Diabetes (self-reported) 1.1 1.7 3.7 1.2 -0.8 1.3 1.0 1.7 0.1 1.4 1.9
Hayfever/allergic rhinitis (self-reported) 2.4 3.2 5.7 2.1 -1.7 1.6 2.4 1.4 1.3 1.8 1.9
Medication: Ramipril 1.0 1.3 5.5 0.7 -2.3 0.8 0.6 0.5 1.3 1.1 0.1
Medication: Simvastatin 1.6 2.3 5.2 2.0 -0.7 1.5 1.7 1.3 -0.4 1.5 2.3
Fluid intelligence score 1.9 3.9 6.6 -2.3 1.1 -2.0 -2.5 -2.0 -0.2 -2.0 -2.6
Illnesses of siblings 1.6 2.2 4.5 -2.1 1.6 -1.3 -1.6 -0.9 -0.9 -1.5 -1.6
Neuroticism score 0.1 0.1 0.8 -0.2 -0.9 -0.2 0.2 0.0 0.2 0.2 0.1
Weight 0.2 0.8 1.7 0.6 -1.1 0.2 0.6 0.0 1.2 0.8 1.3
Impedance of arm (right) 0.8 3.5 9.7 -1.2 3.1 -1.5 -1.6 -1.5 -2.4 -1.9 -1.0
Arm fat percentage (right) 4.5 17.6 21.3 4.3 -4.6 4.1 4.3 3.6 3.4 4.6 4.5
Trunk fat-free mass 0.2 1.1 2.3 -1.3 0.5 -1.4 -0.7 -1.5 0.9 -0.7 -1.0
Hip circumference 0.1 0.5 2.0 -0.3 -0.5 -1.1 -0.1 -1.4 0.5 -0.4 0.3
Time employed in main current job 0.6 0.6 1.1 -1.0 1.0 -0.8 -0.8 -0.9 -0.4 -0.8 -0.4
Alcohol intake versus 10 years previously 0.1 0.1 0.4 -0.4 -0.3 -0.2 -0.6 0.0 -0.4 -0.4 0.4
Father’s age at death 0.1 0.2 0.6 -0.2 0.2 0.2 -0.5 0.1 0.8 -0.1 -0.7
Worrier / anxious feelings 0.1 0.2 0.4 -0.6 -0.3 -0.6 -0.1 -0.6 -0.4 -0.4 -0.1
Frequency of tiredness / lethargy in last 2 weeks 3.6 5.8 7.9 2.6 -2.6 2.5 2.3 2.4 1.2 2.5 2.8
Falls in the last year 2.9 3.9 5.0 1.6 -2.0 2.2 1.7 2.2 2.0 2.2 1.6
Hair/balding pattern: Pattern 3 1.1 1.7 4.8 0.6 -1.9 0.9 1.2 0.5 2.2 1.3 0.3
Number of live births 1.1 1.5 2.3 1.1 -1.0 1.3 1.5 1.3 1.0 1.4 1.0
Forced expiratory volume in 1-second (FEV1) 5.1 17.1 24.8 -4.8 3.3 -4.8 -3.6 -5.0 -0.9 -4.3 -4.9
Pulse rate 2.4 4.0 5.6 1.9 -1.9 2.1 2.0 1.8 2.1 2.4 1.8
Happiness 1.6 2.0 5.7 0.6 -2.4 1.2 0.9 1.0 1.9 1.4 0.8
Noisy workplace 0.9 1.1 2.5 1.6 -0.4 0.7 1.5 0.5 -0.4 0.9 1.6
Qualifications: A levels/AS levels or equivalent 1.3 2.9 6.3 -2.3 -0.0 -1.6 -1.5 -1.9 0.9 -1.4 -2.5
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.4 -0.5 -0.5 -0.6 -0.3 -0.7 0.4 -0.4 -0.2
Mouth/teeth dental problems: Dentures 0.1 0.1 0.3 -0.2 -0.6 0.2 -0.5 0.2 0.3 0.1 -0.0
Asthma 7.1 14.0 19.0 4.2 -2.8 3.9 4.4 3.5 2.8 4.3 3.8
Medication: Ibuprofen (e.g. Nurofen) 1.2 1.5 3.2 -1.5 -1.0 -1.1 -0.9 -1.4 1.2 -0.5 -1.8
Medication: Cholesterol lowering 0.1 0.1 0.2 0.3 -0.3 0.1 0.5 -0.1 -0.4 0.1 0.4
Depression (self-reported) 2.4 2.9 6.0 1.4 -1.1 2.0 1.3 2.5 1.3 1.8 1.8
Medication: Lansoprazole 0.3 0.3 0.6 0.5 -0.8 0.5 0.6 0.4 0.4 0.6 0.7
Prospective memory result 0.4 0.4 1.6 0.1 -0.2 -0.8 0.2 -1.3 -1.0 -0.5 -0.2
Lung cancer (father) 0.9 1.1 2.5 1.2 -0.1 0.8 1.4 1.0 -0.4 1.0 1.6
Illnesses of mother 0.1 0.1 0.3 -0.3 -0.1 0.2 -0.0 0.4 -0.5 -0.1 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 4.0 12.7 18.5 -4.3 2.3 -4.1 -3.1 -4.3 -0.5 -3.7 -4.3
Pulse wave Arterial Stiffness index 3.2 3.7 7.1 1.5 -1.6 2.0 1.9 1.9 2.7 2.3 1.1
Impedance of arm (left) 1.3 6.2 13.5 -1.9 3.7 -2.1 -2.6 -1.9 -3.0 -2.7 -1.4
Arm fat mass (right) 2.1 8.7 11.6 3.0 -3.4 2.6 2.9 2.3 2.7 3.2 3.3
Trunk predicted mass 0.2 1.1 2.3 -1.3 0.5 -1.4 -0.7 -1.5 0.9 -0.7 -1.0
Standing height 4.3 42.3 66.9 -6.4 8.2 -6.9 -6.6 -6.5 -4.8 -6.9 -5.1
Length of working week for main job 0.1 0.1 0.6 -0.2 -0.2 -0.6 -0.2 -0.7 -0.1 -0.3 -0.1
Exposure to tobacco smoke at home 1.0 1.1 3.0 1.2 0.9 0.1 0.8 0.2 -1.7 -0.0 1.7
Breastfed as a baby 0.3 0.4 0.7 -0.4 0.7 -0.7 -0.4 -0.9 -0.5 -0.6 -0.7
Tense / ‘highly strung’ 0.6 0.9 2.0 -1.4 -1.1 -0.3 -0.8 -0.1 1.4 -0.1 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 9.4 14.3 17.9 3.4 -4.2 3.7 3.9 4.0 3.2 4.2 3.5
Hair/balding pattern: Pattern 4 0.0 0.1 0.3 -0.1 0.5 0.4 -0.1 0.6 0.1 0.1 -0.2
Birth weight of first child 3.0 5.5 7.6 -2.5 2.2 -2.7 -1.9 -2.8 -0.7 -2.5 -2.6
Peak expiratory flow (PEF) 4.9 11.4 17.2 -3.7 3.0 -3.8 -2.9 -4.1 -0.7 -3.4 -4.2
Pulse wave reflection index 0.1 0.2 0.6 0.1 -0.8 0.0 0.5 -0.1 0.6 0.3 -0.0
Ever highly irritable/argumentative for 2 days 0.0 0.0 0.1 0.1 -0.3 -0.3 0.0 -0.2 -0.1 -0.1 0.1
Loud music exposure frequency 0.1 0.1 0.5 0.4 -0.0 -0.0 0.5 -0.2 -0.0 0.2 0.7
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 0.7 -0.8 0.3 -0.8 -0.5 -0.9 0.3 -0.7 -0.7
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.5 -0.1 -0.5 0.4 -0.1 0.7 0.2 0.2 0.1
Blood clot in the leg (DVT) 1.3 1.7 3.7 1.4 -1.5 1.3 1.1 1.3 -0.1 1.2 1.9
Medication: Paracetamol 0.6 0.9 2.7 -1.0 -1.6 -0.6 -0.7 -0.7 1.5 -0.1 -0.5
Headache pain in last month 1.4 2.5 4.0 1.1 -2.0 1.7 1.4 1.4 2.0 1.9 0.8
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.9 0.3 1.0 -0.4 0.1 -0.5 -0.2 -0.3 0.2
Glaucoma (self-reported) 0.2 0.2 1.1 -0.5 -0.5 -0.1 -1.0 -0.1 -0.1 -0.3 -0.5
Gout (self-reported) 1.7 2.3 3.6 -1.1 1.6 -1.5 -1.9 -1.4 -1.8 -1.8 -0.5
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.5 0.5 -0.5 0.2 0.2 0.2 -0.4 0.2 0.7
Medication: Amlodipine 0.4 0.6 1.8 -1.2 -0.5 -0.1 -0.4 -0.0 1.1 0.0 -1.4
Medication: Ventolin 100micrograms inhaler 1.0 1.2 2.8 1.7 -0.2 1.0 1.5 0.8 -0.0 1.0 1.4
Birth weight 1.7 3.7 7.2 2.4 -1.4 1.5 2.7 1.0 1.0 2.1 2.5
Chronic bronchitis/emphysema (mother) 0.3 0.4 2.1 0.3 1.5 -0.1 0.8 -0.0 -0.1 0.0 0.5
High blood pressure (siblings) 0.7 1.1 3.2 0.6 -1.8 0.8 0.5 0.5 1.6 1.0 0.4
Forced vital capacity (FVC), Best measure 4.6 16.7 24.2 -4.8 2.9 -4.8 -3.6 -4.9 -1.1 -4.3 -4.7
Body fat percentage 0.9 3.4 8.4 2.1 -1.8 1.6 1.7 1.4 0.9 1.8 2.9
Leg fat percentage (right) 1.2 4.3 9.7 2.6 -1.8 1.8 2.2 1.6 0.4 1.9 3.1
Arm fat-free mass (right) 0.2 1.2 2.6 -1.2 0.8 -1.6 -1.0 -1.6 0.0 -1.0 -0.5
Exposure to tobacco smoke outside home 0.4 0.5 1.0 -0.6 1.0 -0.8 -0.8 -0.5 -0.5 -0.8 -0.3
Comparative body size at age 10 0.6 1.8 5.0 0.2 1.1 -1.6 0.1 -1.9 -2.2 -1.2 0.7
Number of full brothers 0.3 0.4 1.1 -0.8 -0.2 -0.4 -0.2 -0.1 0.9 -0.2 -1.0
Worry too long after embarrassment 2.5 4.2 6.6 2.3 -1.4 2.4 2.2 2.6 0.6 2.1 2.1
Seen a psychiatrist for nerves, anxiety, tension or depression 3.5 4.5 11.0 0.7 -3.3 1.5 1.8 1.6 3.3 2.2 1.1
Wheeze or whistling in the chest in last year 3.7 6.6 8.7 2.1 -3.0 2.6 2.6 2.6 2.5 2.9 2.2
Number of children fathered 0.1 0.1 0.4 -0.2 0.6 0.3 0.1 0.6 0.1 0.0 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 2.6 -0.7 -1.6 -0.2 0.1 -0.7 1.6 -0.0 -1.1
Age at first live birth 0.9 1.6 3.2 -0.8 1.7 -1.4 -0.8 -1.8 -0.5 -1.2 -1.3
Pulse wave peak to peak time 4.5 5.3 8.2 -1.9 2.2 -2.4 -2.4 -2.2 -2.9 -2.7 -1.5
Health satisfaction 6.4 8.3 10.8 2.9 -3.2 2.8 3.2 2.4 1.7 3.1 3.3
Shortness of breath walking on level ground 3.6 4.3 5.7 1.9 -2.0 2.2 2.2 2.2 2.0 2.4 1.8
Qualifications: College or University degree 0.9 2.7 11.2 -1.3 -1.9 0.1 -0.3 -0.2 3.3 0.3 -2.2
Eye problems/disorders: None of the above 0.4 0.5 2.4 0.0 1.6 -0.2 0.2 -0.1 -1.1 -0.4 0.3
Mouth/teeth dental problems: Loose teeth 0.8 0.9 3.2 -0.3 -1.2 0.7 0.1 1.0 1.8 0.7 -0.7
Emphysema/chronic bronchitis 0.5 0.5 1.5 1.0 -0.0 0.6 1.2 0.4 0.6 0.8 0.5
Medication for pain relief, constipation, heartburn 1.4 2.4 10.0 -0.1 3.2 -0.5 -0.6 -0.2 -2.7 -1.3 -0.3
Neck or shoulder pain in last month 1.3 1.8 2.9 -1.2 1.3 -1.7 -1.4 -1.4 -1.3 -1.6 -0.2
Medication: Blood pressure 0.4 0.8 2.0 -1.4 -0.7 -0.3 -1.1 -0.2 0.7 -0.3 -1.3
Angina (self-reported) 0.9 1.1 2.2 -1.5 -0.5 -1.2 -1.0 -1.2 0.3 -0.8 -1.5
Migraine (self-reported) 2.0 2.5 4.7 0.9 -2.2 1.6 1.2 1.5 2.0 1.8 1.2
Medication: Ibuprofen 0.8 0.9 1.8 -1.1 -0.7 -0.8 -1.0 -1.1 0.8 -0.4 -1.3
Medication: Allopurinol 5.7 7.5 10.6 -2.0 3.3 -2.8 -3.0 -2.6 -3.2 -3.2 -1.3
Medication: Omeprazole 2.7 3.2 5.0 1.6 -2.2 1.7 1.9 1.2 2.2 2.0 1.2
Medication: Seretide 50 evohaler 1.6 1.8 5.3 1.9 0.5 0.6 1.1 0.7 -1.8 0.4 2.3
Mean time to correctly identify matches 0.9 1.7 8.2 1.2 1.3 0.2 0.5 0.4 -2.9 -0.2 1.5
Heart disease (mother) 0.2 0.2 1.1 0.3 -1.0 -0.1 0.3 -0.3 0.4 0.2 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 2.5 -1.3 0.1 -0.7 -0.8 -0.7 0.7 -0.5 -1.6
Whole body fat mass 0.4 1.8 4.8 1.3 -1.6 0.9 1.1 0.7 1.0 1.3 2.2
Leg fat mass (right) 0.7 2.7 6.4 1.9 -1.6 1.3 1.8 1.1 0.9 1.6 2.5
Arm predicted mass (right) 0.3 1.4 3.0 -1.4 0.5 -1.7 -1.2 -1.7 0.2 -1.1 -0.8
Pulse rate, automated reading 1.2 3.9 6.4 2.4 -1.7 1.9 2.0 1.6 1.0 2.2 2.5
Alcohol intake frequency. 0.5 1.1 3.0 1.3 -0.7 0.9 0.9 1.0 -0.2 0.9 1.7
Comparative height size at age 10 3.9 21.4 28.1 -4.8 5.3 -5.2 -4.3 -5.1 -3.3 -4.9 -3.7
Number of full sisters 3.9 4.8 6.3 1.7 -2.3 2.2 2.5 2.4 1.7 2.5 2.0
Suffer from ‘nerves’ 1.3 2.0 4.5 -2.1 -0.1 -1.5 -1.2 -1.4 0.3 -1.1 -2.1
Overall health rating 7.6 16.4 20.8 4.0 -4.6 3.9 4.0 3.7 3.0 4.5 4.5
Chest pain or discomfort 3.3 4.8 8.1 1.9 -2.8 2.2 2.2 2.0 2.3 2.3 1.6
Had major operations 0.2 0.2 0.9 -0.6 -0.6 -0.2 0.2 -0.3 0.9 0.1 -0.1
Age at last live birth 0.3 0.4 0.8 -0.3 0.9 -0.5 -0.0 -0.7 0.7 -0.1 -0.9
Family relationship satisfaction 0.3 0.3 1.1 0.6 -0.2 0.4 0.6 0.4 0.0 0.6 1.1
Leg pain on walking 1.2 1.5 3.0 1.4 -1.4 1.1 1.7 0.6 1.0 1.5 0.6
Qualifications: NVQ or HND or HNC or equivalent 1.8 2.2 5.1 2.1 -0.6 1.3 1.4 1.4 -0.3 1.2 2.2
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.6 -0.7 1.6 -1.0 -0.6 -0.9 -0.6 -1.0 -0.8
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.9 -0.6 0.3 -0.1 -0.8 -0.2 0.1 -0.4 -1.4
Medication: Aspirin 0.2 0.3 0.7 -0.4 -0.8 -0.3 -0.6 -0.4 0.2 -0.3 -0.7
Supplements: Vitamin C 0.5 0.6 1.0 -1.0 0.3 -0.8 -0.7 -0.9 -0.2 -0.9 -1.0
Knee pain experienced in last month 0.1 0.1 0.5 0.4 -0.2 -0.2 0.4 -0.3 0.1 0.1 0.7
Hypertension (Self-reported) 0.6 1.7 3.3 0.2 -1.6 1.8 -0.4 1.8 1.6 1.5 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.4 -0.2 -0.3 0.2 -0.2 0.0 0.6 0.1 -0.4
Illnesses of father: Heart disease 1.1 1.5 3.7 0.8 -1.9 1.0 1.5 1.0 1.3 1.2 0.6
Illnesses of siblings: Diabetes 0.4 0.5 1.3 1.1 -0.1 0.4 0.9 0.5 -0.3 0.5 0.9
Smoking status: Previous 1.1 1.6 3.8 -0.2 -1.1 1.5 -0.1 1.8 2.0 1.3 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 2.0 4.1 11.7 -1.4 3.4 -1.8 -1.6 -1.4 -2.5 -2.0 -0.7
Whole body fat-free mass 0.1 0.8 2.1 -1.0 -0.1 -1.0 -0.5 -1.2 1.4 -0.3 -0.7
Leg fat-free mass (right) 0.2 1.3 6.9 -0.1 -1.5 0.1 0.4 -0.2 2.6 0.9 0.1
Arm fat percentage (left) 3.7 14.9 19.5 4.0 -4.4 3.8 3.7 3.4 3.1 4.2 4.2
Average weekly red wine intake 2.9 4.3 10.0 -2.1 -2.9 0.4 -1.1 0.4 3.2 0.4 -3.2
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.4 0.0 0.3 -0.3 0.2 -0.6 0.2 -0.2 -0.6
Mood swings 1.2 2.2 5.6 1.4 -2.4 1.2 1.4 1.1 0.5 1.4 1.8
Loneliness, isolation 0.4 0.5 2.0 0.2 -1.4 0.5 0.2 0.4 0.9 0.9 0.4
Long-standing illness, disability or infirmity 3.9 5.9 11.2 2.4 -3.3 2.2 2.4 1.9 1.5 2.6 2.7
Ever had bowel cancer screening 0.4 0.5 0.7 0.7 -0.7 0.6 0.5 0.3 0.8 0.7 0.8
Diabetes diagnosed by doctor 2.1 3.4 6.7 1.6 -1.6 2.2 1.2 2.6 0.8 1.9 2.2
Ever had stillbirth, spontaneous miscarriage or termination 5.2 5.6 7.7 2.1 -2.5 2.8 2.1 2.7 2.5 2.7 1.3
Friendships satisfaction 0.4 0.5 1.6 -0.3 -1.1 0.5 0.2 0.6 1.2 0.6 -0.2
Qualifications: nursing, teaching 1.4 2.2 5.2 -2.0 0.3 -1.5 -1.2 -1.4 0.9 -1.2 -2.3
Commuting to job workplace: Walk 0.2 0.2 0.4 0.2 -0.7 0.4 0.1 0.2 0.6 0.5 0.2
Eye problems/disorders: Cataract 0.3 0.3 1.3 -0.1 -1.1 -0.2 -0.1 -0.4 0.9 0.1 -0.3
Mouth/teeth dental problems: Mouth ulcers 2.0 3.2 5.9 -1.6 1.6 -2.2 -1.4 -2.4 -1.1 -1.9 -1.6
Medication for cholesterol 0.8 1.3 2.1 -1.4 0.5 -1.4 -0.6 -1.4 -0.4 -1.3 -1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.7 0.3 -1.3 0.4 0.9 0.4 1.2 0.8 0.6
Back pain experienced in last month 0.1 0.1 0.5 0.1 -0.5 0.1 0.1 0.1 0.7 0.2 0.5
Mineral and other dietary supplements 3.1 4.2 12.1 2.9 -0.3 1.4 2.2 1.5 -1.3 1.4 3.5
Breast cancer (self-reported) 0.2 0.3 0.9 0.5 0.2 -0.2 0.2 -0.4 -0.9 -0.0 0.8
Asthma (self-reported) 6.5 12.9 18.6 4.2 -2.6 3.6 4.3 3.1 2.6 4.1 3.7
Osteoporosis (self-reported) 1.4 1.8 3.2 1.6 -1.0 1.4 1.8 1.3 0.3 1.5 1.2
Osteoarthritis (self-reported) 0.3 0.3 1.1 0.0 0.2 -0.7 0.1 -0.8 -1.1 -0.5 0.0
Medication: Aspirin 0.3 0.4 0.7 -0.6 -0.7 -0.6 -0.8 -0.6 -0.1 -0.6 -0.8
Medication: Gliclazide 0.4 0.5 1.2 -0.1 -1.1 0.7 -0.4 1.0 0.9 0.6 -0.2
Illnesses of father: None of the above (group 1) 0.8 1.0 4.8 -0.1 2.2 -0.1 -0.6 0.4 -1.5 -0.6 0.4
Smoking status: Current 1.7 2.7 4.9 2.1 -0.5 1.6 2.2 1.8 -0.2 1.5 2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.6 3.3 -1.5 -0.9 -1.1 -0.2 -1.5 1.5 -0.7 -1.8
Whole body water mass 0.1 0.7 2.2 -0.8 -0.3 -0.9 -0.3 -1.1 1.5 -0.1 -0.6
Leg predicted mass (right) 0.2 1.3 7.0 -0.1 -1.5 0.1 0.4 -0.2 2.6 0.9 0.1
Arm fat mass (left) 1.8 7.3 10.6 2.7 -3.2 2.4 2.6 2.0 2.5 3.0 3.1
Number of self-reported non-cancer illnesses 5.6 9.7 15.8 2.9 -4.0 3.2 2.7 3.0 2.2 3.4 3.2
Average weekly champagne plus white wine intake 0.6 0.8 1.9 -0.8 0.7 -1.1 -0.2 -1.1 0.3 -0.8 -1.4
Miserableness 0.2 0.4 1.3 0.3 -1.1 0.4 0.7 0.6 0.2 0.5 0.4
Guilty feelings 0.4 0.6 1.3 -1.1 -0.0 -0.8 -0.7 -0.8 -0.1 -0.6 -1.0
Wears glasses or contact lenses 1.0 1.2 1.5 1.0 -1.2 1.1 0.9 1.1 1.1 1.1 1.1
Ever taken oral contraceptive pill 0.8 0.9 2.1 -1.4 0.1 -1.2 -0.4 -1.2 0.3 -0.8 -1.2
Hearing aid user 1.0 1.1 2.3 1.4 -1.2 0.6 1.3 0.5 -0.4 0.8 1.5
Mother’s age at death 0.2 0.3 1.1 0.5 -0.2 0.6 0.3 0.3 1.0 0.5 0.1
Financial situation satisfaction 0.8 1.0 2.9 1.2 -0.1 0.7 1.0 1.1 -0.5 0.6 1.7
Tinnitus: Yes, now most or all of the time 0.9 1.0 1.7 1.3 -1.0 0.9 1.3 0.3 0.4 1.1 1.2
Commuting to job workplace: Public transport 0.5 0.6 2.0 -0.8 -1.1 0.1 -0.4 0.1 1.4 0.2 -0.7
Eye problems/disorders: Glaucoma 0.1 0.2 0.7 -0.5 -0.3 -0.1 -0.8 -0.1 -0.1 -0.2 -0.5
Medication: Blood pressure 0.6 1.1 2.6 0.9 -0.8 1.6 -0.0 1.6 0.6 1.2 0.8
Pain type(s) experienced in last month: Hip pain 0.3 0.3 0.6 -0.8 0.1 -0.7 -0.6 -0.7 -0.1 -0.6 -0.5
Supplements: Fish oil (including cod liver oil) 5.2 6.9 18.3 -3.7 0.6 -1.7 -3.3 -1.5 1.5 -2.0 -4.3
High cholesterol (Self-reported) 2.2 3.8 6.5 2.3 -1.2 2.1 2.3 1.9 0.3 2.0 2.5
Medication: Bendroflumethiazide 1.2 1.8 2.7 1.3 -1.6 1.6 0.8 1.5 1.1 1.5 1.1
Medication: Paracetamol 0.3 0.5 2.4 -0.1 -1.6 -0.2 -0.4 -0.3 0.9 0.1 0.1
Medication: Lisinopril 0.9 1.1 1.6 -1.2 1.1 -0.8 -1.2 -0.7 -1.0 -1.1 -1.3
Medication: Atorvastatin 0.0 0.0 0.2 -0.0 -0.1 0.1 -0.2 0.2 -0.5 -0.1 0.2
Illnesses of father: High blood pressure 0.5 0.7 2.2 -0.7 -0.7 -0.8 -0.3 -1.5 0.5 -0.4 -0.9
Alcohol drinker status: Never 0.2 0.3 0.8 0.7 -0.3 0.0 0.7 -0.2 -0.2 0.3 0.9
Ever smoked 1.0 1.7 4.1 0.1 -1.1 1.5 0.9 1.7 2.0 1.5 -0.1
Basal metabolic rate 0.1 0.5 2.0 -0.5 -0.5 -0.7 -0.1 -0.9 1.4 0.1 -0.1
Leg fat percentage (left) 1.1 3.8 8.2 2.4 -2.0 1.7 2.0 1.4 0.7 1.8 2.9
Arm fat-free mass (left) 0.2 0.8 2.3 -1.0 0.3 -1.4 -0.7 -1.5 0.4 -0.7 -0.4
Number of operations (self-reported) 1.9 2.9 5.4 2.2 -1.5 1.3 2.2 1.0 0.3 1.7 2.3
Average weekly beer plus cider intake 1.6 2.3 4.0 1.5 -0.4 1.7 1.5 2.0 0.8 1.7 1.9
Irritability 0.4 0.8 3.9 -0.8 -1.1 0.0 -0.2 0.3 2.0 0.4 -0.3
Risk taking 0.7 1.0 3.4 -1.0 -1.1 0.6 -0.6 0.7 1.8 0.4 -1.1
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.9 0.2 -1.0 0.4 -0.1 0.1 0.4 0.4 0.4
Fractured/broken bones in last 5 years 0.3 0.3 1.3 -0.0 -0.9 0.1 0.4 -0.2 1.1 0.5 -0.3
Age started oral contraceptive pill 0.8 1.0 1.8 0.8 -0.8 1.4 0.7 1.2 0.9 1.2 0.9
Diastolic blood pressure, automated reading 0.0 0.1 0.4 0.6 -0.4 0.3 0.1 -0.1 0.4 0.4 -0.3
Ever depressed for a whole week 0.3 0.3 0.6 0.8 -0.4 0.6 0.6 0.7 0.0 0.6 0.7
Unable to work because of sickness or disability 0.6 0.8 3.3 0.9 0.3 -0.5 0.6 -0.8 -1.8 -0.2 1.1
Commuting to job workplace: Cycle 2.0 2.4 7.9 -2.1 -1.3 -0.7 -1.0 -0.8 1.7 -0.5 -2.8
Myopia 0.7 1.0 2.6 -1.3 -1.3 -0.2 -0.7 -0.4 1.1 -0.2 -1.6
Vascular/heart problems diagnosed by doctor 0.9 2.3 4.3 -0.3 2.0 -1.9 -0.1 -1.9 -2.1 -1.7 -0.2
Cholesterol lowering medication 3.4 5.0 8.7 2.8 -1.7 2.4 2.1 2.2 0.4 2.3 3.0
Medication: Omeprazole (e.g. Zanprol) 2.7 3.3 7.8 1.1 -2.5 1.7 1.4 1.3 2.8 1.9 0.7
Pain experienced in last month 0.3 0.5 1.6 -0.4 0.9 -0.2 -0.8 -0.1 -0.6 -0.6 -1.3
Supplements: Calcium 3.9 4.3 8.8 -2.8 1.1 -2.2 -1.8 -2.1 -0.3 -2.0 -3.0
Basal cell carcinoma (self-reported) 0.6 0.7 2.3 1.2 -0.4 0.2 0.9 0.0 -0.7 0.4 1.5
Heart attack/myocardial infarction (self-reported) 2.7 3.5 6.6 -2.4 0.0 -2.0 -2.0 -2.1 -0.6 -1.8 -2.6
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 3.2 1.3 -1.3 1.2 0.9 1.4 -0.2 1.1 1.8
Heart disease (siblings) 1.6 1.9 4.8 2.2 -0.7 1.1 1.7 0.7 -0.5 1.1 2.1
Alcohol drinker status: Previous 0.8 1.0 3.4 -0.7 -0.9 0.7 -0.4 1.1 1.8 0.6 -0.7
Pack years of smoking 0.9 1.3 3.8 1.5 0.1 0.8 1.9 0.7 -0.1 1.1 1.4
Impedance of whole body 3.3 16.6 33.0 -3.1 5.7 -3.6 -3.9 -3.2 -5.2 -4.5 -2.1
Leg fat mass (left) 0.7 2.6 5.8 1.8 -1.8 1.2 1.6 1.0 1.1 1.6 2.4
Arm predicted mass (left) 0.1 0.6 2.0 -0.7 0.2 -1.2 -0.4 -1.4 0.3 -0.6 -0.2