[Hub]/) : Traits : Bipolar Disorder or Schizophrenia :

chr2:197,134,790-199,259,516

Best TWAS P=1.58e-11 · Best GWAS P=6.62e-11 conditioned to 0.114

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SF3B1 0.06 0.07 enet 10 0.07 2.5e-09 6.3 6.4 1.8e-10 0.99 0.02 0.98 FALSE
2 GTEx Breast Mammary Tissue SF3B1 0.06 0.06 lasso 4 0.03 6.6e-03 6.4 6.2 4.8e-10 0.98 0.04 0.92 FALSE
3 GTEx Breast Mammary Tissue (Female) SF3B1 0.05 -0.01 lasso 3 -0.01 8.1e-01 6.5 5.9 3.1e-09 0.91 0.03 0.43 FALSE
4 GTEx Esophagus Mucosa SF3B1 0.04 0.02 lasso 4 0.01 5.7e-02 6.3 6.2 4.2e-10 0.98 0.05 0.85 FALSE
5 GTEx Lung SF3B1 0.06 0.04 enet 23 0.02 2.2e-02 6.3 5.3 1.2e-07 0.83 0.03 0.94 FALSE
6 GTEx Nerve Tibial SF3B1 0.06 0.09 lasso 8 0.08 3.3e-06 6.5 6.3 3.5e-10 0.97 0.07 0.93 FALSE
7 GTEx Pituitary HSPD1 0.10 0.03 enet 12 0.06 1.3e-02 5.1 6.7 1.6e-11 0.69 0.07 0.40 TRUE
8 GTEx Skin Not Sun Exposed Suprapubic SF3B1 0.08 0.00 enet 19 0.01 1.6e-01 6.3 6.0 2.1e-09 0.84 0.04 0.88 FALSE
9 GTEx Skin Sun Exposed Lower leg ANKRD44 0.30 0.13 enet 16 0.16 2.3e-13 2.8 5.1 2.9e-07 0.40 1.00 0.00 FALSE
10 GTEx Stomach SF3B1 0.11 0.00 enet 19 0.00 4.0e-01 5.7 5.8 7.4e-09 0.65 0.06 0.44 FALSE
11 GTEx Testis SF3B1 0.10 0.07 enet 17 0.08 2.6e-04 6.3 5.7 1.4e-08 0.95 0.04 0.96 FALSE
12 GTEx Thyroid SF3B1 0.04 0.02 enet 14 0.02 2.0e-02 5.3 5.1 2.7e-07 0.88 0.09 0.83 FALSE
13 NTR Blood ANKRD44 0.03 0.00 bslmm 417 0.02 2.7e-06 5.6 -6.3 2.7e-10 -0.61 0.07 0.89 FALSE
14 ROSMAP Brain Pre-frontal Cortex SF3B1 0.02 0.01 blup 336 0.01 6.2e-03 5.8 5.9 3.2e-09 0.93 0.06 0.91 FALSE
15 ROSMAP Brain Pre-frontal Cortex RFTN2 0.03 0.04 blup 351 0.03 1.5e-04 5.5 -5.6 2.5e-08 -0.85 0.26 0.72 FALSE
16 YFS Blood ANKRD44 0.02 0.00 blup 416 0.01 6.3e-04 3.0 -6.6 5.1e-11 -0.59 0.10 0.64 TRUE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RFTN2 0.05 0.01 blup 61 0.02 3.1e-02 6.3 5.6 2.2e-08 0.92 0.02 0.70 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma PLCL1 0.07 0.06 blup 130 0.07 1.8e-07 5.7 -6.1 9.6e-10 -0.73 0.03 0.97 FALSE