Hub : Genes

FILIP1L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.071 0.028 9.3e-06 0.050 0.043 0.04 0.044 0.044 9.5e-07 4.7e-06 1.1e-05 3.7e-06 3.8e-06
2 GTEx Cells Transformed fibroblasts 0.151 0.041 1.8e-11 0.206 NA 0.20 NA 0.199 2.1e-15 NA 5.5e-15 NA 6.7e-15

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.9 1.5 2.8 1.7 -0.4
Bipolar Disorder or Schizophrenia 1.0 2.4 4.7 2.2 0.1
Depressed Affect (Nagel 2018) 0.2 0.5 0.5 0.7 -0.7
Depression (Nagel 2018) 0.8 1.3 1.4 1.1 -1.2
Intelligence (Savage-Jansen 2018) 0.6 1.7 2.3 1.5 -1.1
Neuroticism (Nagel 2018) 0.2 0.6 0.8 0.6 -0.9
Schizophrenia (2018) 0.5 1.1 2.0 1.4 0.4
Schizophrenia vs Biploar Disorder 0.0 0.1 0.1 -0.3 -0.1
Worry (Nagel 2018) 0.0 0.0 0.0 -0.0 0.2
Alzheimer’s Disease (in mother) 0.2 0.3 0.3 -0.5 0.5
Alzheimer’s Disease (in father) 0.6 0.7 1.2 0.3 -1.1
Alzheimer’s Disease (including proxy) 0.2 0.3 0.4 -0.6 -0.4
Crohns Disease (2017) 1.7 3.7 5.8 1.3 -2.4
Irritable Bowel Disease (IBD) 2.3 5.4 8.1 1.6 -2.9
Ulcerative Colitis (UC) 1.6 3.1 4.4 1.3 -2.1
Major Depression (MDD) 0.5 0.6 1.0 0.5 1.0
Reaction Time 0.1 0.3 0.4 0.4 -0.6
Verbal and Numeric Reasoning (VNR) 0.0 0.1 0.1 0.3 -0.1
Breast Cancer 9.6 23.1 29.7 -4.1 5.5
Ovarian Cancer 3.4 4.5 5.2 -2.0 2.3
Prostate Cancer 1.2 1.7 2.4 1.6 -1.0
Age at First Birth 0.1 0.1 0.2 0.4 -0.0
Bipolar Disorder (2011) 0.8 0.8 1.6 -0.1 1.3
Body Mass Index (BMI) (2010) 0.3 0.4 0.7 0.3 -0.8
Coronary Artery Disease (CAD) 0.3 0.4 0.7 -0.9 -0.1
Crohns Disease (2012) 1.6 2.6 3.7 1.2 -1.9
Mean Putamen Volume 0.4 0.4 0.6 0.5 -0.8
Fasting Glucose 0.0 0.0 0.0 0.1 0.1
HbA1C 0.0 0.0 0.0 -0.0 0.0
HDL Cholesterol 0.0 0.0 0.1 -0.0 0.3
LDL Cholesterol 0.5 0.8 0.9 -0.9 0.9
Lupus 2.3 3.5 6.2 -0.8 2.5
Neuroticism (2016) 0.4 0.5 0.7 0.6 -0.8
Primary Biliary Cirrhosis 1.1 1.6 2.3 1.5 -0.9
Rheumatoid Arthritis 0.8 1.2 2.3 -0.2 1.5
Schizophrenia (2014) 0.6 1.4 2.8 1.7 -0.0
Triglycerides 2.7 4.4 5.2 -2.3 1.9
Type 2 Diabetes (T2D) (2012) 1.0 1.2 2.0 -0.6 1.4
Ulcerative Colitis 0.8 1.2 1.3 1.0 -1.2
Blood Eosinophil Count 0.0 0.1 0.2 -0.5 0.3
Blood Platelet Count 0.2 2.1 3.1 -1.8 1.1
Blood Red Count 0.1 1.4 2.1 -1.4 0.8
Blood White Count 0.5 3.5 6.2 0.9 -2.5
Heel T-Score 0.5 4.3 5.6 -1.7 2.4
BMI 0.9 5.0 6.6 2.6 -1.8
Height 0.1 1.8 2.6 -1.6 1.0
Waist Hip Ratio (WHR) 1.9 8.7 16.7 0.8 -4.1
Systolic Blood Pressure 1.1 5.6 9.5 -1.3 3.1
Smoking Status 0.0 0.1 0.1 0.4 -0.3
Allergy or Eczema 0.5 1.4 1.7 -1.0 1.3
Cardiovascular Disease 1.7 5.6 7.6 -1.9 2.8
Hypothyroidism (self reported) 0.9 2.0 2.1 -1.3 1.5
Respiratory disease 0.2 0.5 1.0 -0.1 -1.0
Type 2 Diabetes (T2D) (2018) 1.2 2.2 2.5 -1.6 1.4
Lung FEV1/FVC ratio 0.8 4.2 4.5 -2.0 2.1
Lung FVC 0.7 3.8 7.5 2.7 -0.2
Neuroticism 0.0 0.0 0.0 -0.1 -0.0
Chronotype (morning person) 0.2 0.4 0.8 0.2 0.9
Hair Pigment 0.3 8.4 8.5 2.9 -2.9
Tanning 0.2 1.9 3.7 0.3 -1.9
Hand grip strength (left) 1.1 3.0 5.9 0.1 2.4
Number of treatments/medications taken 0.6 1.0 1.9 1.4 -0.3
Average weekly spirits intake 0.5 0.7 0.8 -0.9 0.7
Sensitivity / hurt feelings 0.3 0.5 1.1 0.2 -1.0
Frequency of depressed mood in last 2 weeks 0.4 0.6 0.8 0.7 -0.9
Hearing difficulty/problems: Yes 4.1 6.3 7.4 2.3 -2.7
Relative age of first facial hair 0.3 0.6 0.8 -0.6 0.9
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.4 -0.2 0.6
Ever used hormone-replacement therapy (HRT) 0.4 0.4 0.6 0.8 -0.6
Ever had hysterectomy (womb removed) 0.3 0.4 0.7 0.4 -0.8
Systolic blood pressure, automated reading 0.3 0.9 1.1 0.9 1.0
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 0.9 -0.9 0.6
Angina 0.6 0.8 1.1 -0.6 1.1
Medication for hormone replacement therapy 0.2 0.2 0.2 0.3 -0.5
Vitamin and mineral supplements 0.6 0.7 1.5 -0.1 -1.2
Supplements: Zinc 4.7 5.1 5.6 2.4 -2.1
Medication: Co-codamol 0.3 0.3 0.4 -0.6 -0.5
Medication: Metformin 0.4 0.5 0.9 -1.0 -0.3
Diabetes (father) 1.8 2.3 2.7 1.4 -1.6
Diabetes (mother) 3.4 4.3 5.3 2.3 -1.8
Severe depression (siblings) 0.1 0.1 0.2 0.3 -0.4
Pack years adult smoking proportion 0.0 0.0 0.0 -0.2 -0.1
Impedance of leg (right) 1.2 5.7 7.2 2.1 -2.7
Leg fat-free mass (left) 0.3 1.5 2.6 -0.7 1.6
Trunk fat percentage 4.0 16.2 20.8 3.4 -4.6
Hand grip strength (right) 0.3 0.9 1.1 1.0 0.8
Townsend deprivation index at recruitment 0.9 1.2 1.5 0.9 -1.2
Current tobacco smoking 0.1 0.2 0.3 0.3 -0.5
Average weekly fortified wine intake 0.2 0.2 0.4 0.4 -0.6
Maternal smoking around birth 3.0 4.4 7.8 -2.8 1.0
Fed-up feelings 2.1 3.8 5.8 1.4 -2.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 1.5 0.8 -1.2
Relative age voice broke 0.8 1.2 1.5 -1.2 0.9
Taking other prescription medications 0.4 0.6 0.8 -0.9 0.7
Age when periods started (menarche) 0.3 0.6 1.1 -1.0 0.5
Bilateral oophorectomy (both ovaries removed) 1.8 2.0 3.0 1.0 -1.7
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.2 0.5 0.4
Tinnitus: Yes, but not now, but have in the past 7.2 7.7 11.2 -2.0 3.4
Qualifications: CSEs or equivalent 0.0 0.0 0.1 0.3 -0.1
Serious illness, injury or assault to yourself 0.2 0.2 0.2 -0.5 0.5
High blood pressure 0.7 1.9 3.2 -0.8 1.8
Hayfever, allergic rhinitis or eczema 0.1 0.1 0.2 -0.3 0.4
Multivitamins +/- minerals 0.2 0.3 0.5 0.2 0.7
Stomach or abdominal pain in last month 0.4 0.5 0.8 0.5 -0.9
Supplements: Glucosamine 0.2 0.3 0.6 -0.8 0.1
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 1.6 1.3 0.4
Medication: Atenolol 0.8 1.0 1.6 -0.7 1.3
Medication: Levothyroxine sodium 1.8 3.1 4.7 -1.3 2.2
Sitting height 0.2 1.4 2.0 -1.4 0.9
Chronic bronchitis/emphysema (father) 1.1 1.3 2.6 0.0 -1.6
High blood pressure (mother) 2.4 3.4 4.8 -1.4 2.2
Body mass index (BMI) 0.3 1.1 1.2 1.1 -1.1
Impedance of leg (left) 1.1 5.2 8.0 1.6 -2.8
Leg predicted mass (left) 0.3 1.6 2.6 -0.7 1.6
Trunk fat mass 1.8 7.5 9.4 2.4 -3.1
Waist circumference 3.3 11.9 17.3 2.6 -4.2
Number of incorrect matches in round 0.4 0.7 1.1 -1.0 0.6
Past tobacco smoking 0.1 0.2 0.4 0.3 -0.6
Alcohol usually taken with meals 0.3 0.5 0.6 0.6 0.8
Nervous feelings 0.1 0.3 0.4 -0.7 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 0.5 0.4 -0.7
Hearing difficulty/problems with background noise 0.0 0.1 0.1 -0.4 0.1
Hair/balding pattern: Pattern 2 0.5 0.6 1.2 1.1 0.3
Had menopause 1.7 2.1 3.0 1.7 -1.1
Had other major operations 1.2 1.5 2.8 1.7 -0.3
Forced vital capacity (FVC) 0.1 0.6 0.8 0.9 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 0.5 0.7 0.3
Ever unenthusiastic/disinterested for a whole week 0.4 0.4 0.8 0.9 -0.3
Qualifications: None of the above 0.1 0.1 0.2 -0.2 -0.5
Financial difficulties in last 2 years 0.4 0.6 1.2 -0.1 1.1
Mouth/teeth dental problems 0.1 0.2 0.3 0.0 -0.5
Heart attack 1.2 1.6 2.3 0.9 -1.5
Allergy 0.4 0.9 1.6 1.3 -0.5
Pain all over the body in last month 0.0 0.0 0.0 0.1 -0.2
Diabetes (self-reported) 0.5 0.7 1.5 -1.2 -0.1
Hayfever/allergic rhinitis (self-reported) 0.0 0.0 0.0 0.2 -0.2
Medication: Ramipril 0.2 0.2 0.4 0.3 -0.6
Medication: Simvastatin 0.0 0.0 0.0 0.1 -0.0
Fluid intelligence score 0.0 0.0 0.0 -0.1 -0.0
Illnesses of siblings 1.0 1.4 2.2 1.5 -0.7
Neuroticism score 0.0 0.1 0.1 0.1 -0.3
Weight 0.1 0.2 0.4 0.6 -0.4
Impedance of arm (right) 3.0 14.2 17.8 3.3 -4.2
Arm fat percentage (right) 2.7 10.7 12.3 3.0 -3.5
Trunk fat-free mass 1.7 9.7 13.8 -2.4 3.7
Hip circumference 1.2 5.1 5.3 2.3 -2.2
Time employed in main current job 0.6 0.7 1.3 -1.1 0.5
Alcohol intake versus 10 years previously 0.5 0.7 1.0 0.6 -1.0
Father’s age at death 1.4 1.9 3.1 1.8 -0.9
Worrier / anxious feelings 0.5 0.9 1.4 1.2 -0.6
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 1.3 1.1 -1.1
Falls in the last year 2.2 3.0 5.1 0.9 -2.3
Hair/balding pattern: Pattern 3 0.3 0.5 0.8 0.4 -0.9
Number of live births 0.8 1.1 1.8 -0.7 1.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.2 0.5 1.1
Pulse rate 0.0 0.1 0.1 -0.2 -0.3
Happiness 0.1 0.2 0.3 -0.5 0.2
Noisy workplace 2.0 2.5 3.3 1.8 -1.3
Qualifications: A levels/AS levels or equivalent 0.0 0.1 0.1 0.2 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 0.9 0.7 -1.0
Mouth/teeth dental problems: Dentures 0.0 0.0 0.0 -0.2 0.1
Asthma 0.2 0.4 0.8 -0.9 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 1.3 1.0 -1.1
Medication: Cholesterol lowering 2.7 4.2 6.2 -2.5 1.5
Depression (self-reported) 2.5 3.0 4.2 2.0 -1.3
Medication: Lansoprazole 1.3 1.4 2.3 1.5 -0.8
Prospective memory result 1.3 1.6 2.4 1.6 -0.9
Lung cancer (father) 0.3 0.3 0.6 -0.3 -0.7
Illnesses of mother 0.2 0.3 0.6 -0.0 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 0.5 0.5 0.7
Pulse wave Arterial Stiffness index 0.1 0.1 0.2 0.5 -0.0
Impedance of arm (left) 3.1 14.3 17.5 3.3 -4.2
Arm fat mass (right) 0.8 3.2 3.3 1.8 -1.8
Trunk predicted mass 1.7 9.6 13.8 -2.3 3.7
Standing height 0.2 2.1 3.0 -1.1 1.7
Length of working week for main job 1.5 1.6 1.7 1.2 -1.3
Exposure to tobacco smoke at home 0.0 0.0 0.0 -0.1 0.0
Breastfed as a baby 0.1 0.1 0.1 -0.3 0.4
Tense / ‘highly strung’ 1.2 2.1 2.2 -1.5 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.0 1.4 1.2 -0.8
Hair/balding pattern: Pattern 4 1.7 4.0 5.2 -2.3 1.7
Birth weight of first child 0.2 0.3 0.4 0.7 -0.4
Peak expiratory flow (PEF) 0.2 0.6 1.1 0.0 1.1
Pulse wave reflection index 0.4 0.5 0.9 0.3 1.0
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.2 -1.1 0.4
Loud music exposure frequency 6.1 6.7 7.2 -2.5 2.7
Qualifications: O levels/GCSEs or equivalent 0.0 0.0 0.1 0.1 -0.3
Mouth/teeth dental problems: Bleeding gums 0.1 0.2 0.3 -0.6 0.0
Blood clot in the leg (DVT) 0.1 0.1 0.1 -0.4 0.0
Medication: Paracetamol 0.1 0.1 0.1 0.3 -0.3
Headache pain in last month 0.7 1.2 2.0 -0.6 1.4
Medication for cholesterol, blood pressure or diabetes 1.2 1.9 2.9 1.7 -1.0
Glaucoma (self-reported) 0.4 0.5 0.8 0.9 0.4
Gout (self-reported) 3.4 4.7 6.8 -2.6 1.6
Hypothyroidism/myxoedema (self-reported) 1.1 2.1 2.5 -1.3 1.6
Medication: Amlodipine 0.6 0.9 1.2 -0.7 1.1
Medication: Ventolin 100micrograms inhaler 0.3 0.3 0.5 -0.7 0.4
Birth weight 0.4 0.9 0.9 0.9 -0.9
Chronic bronchitis/emphysema (mother) 0.2 0.3 0.5 -0.2 0.7
High blood pressure (siblings) 0.1 0.2 0.4 -0.6 0.2
Forced vital capacity (FVC), Best measure 0.2 0.7 1.4 1.2 -0.2
Body fat percentage 3.6 14.2 18.3 3.2 -4.3
Leg fat percentage (right) 2.2 8.0 9.2 2.6 -3.0
Arm fat-free mass (right) 1.3 6.5 8.4 -2.1 2.9
Exposure to tobacco smoke outside home 1.3 1.7 3.0 1.7 -0.6
Comparative body size at age 10 0.5 1.3 1.5 1.2 1.0
Number of full brothers 0.5 0.6 0.7 0.7 -0.9
Worry too long after embarrassment 0.0 0.1 0.1 -0.3 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 0.4 0.3 0.6
Wheeze or whistling in the chest in last year 0.1 0.2 0.3 -0.6 0.0
Number of children fathered 0.3 0.3 0.4 -0.5 0.6
Reason for reducing amount of alcohol drunk: Health precaution 1.1 1.3 2.3 0.5 -1.5
Age at first live birth 0.2 0.4 0.4 0.7 -0.6
Pulse wave peak to peak time 0.1 0.1 0.2 -0.5 -0.0
Health satisfaction 1.0 1.2 2.4 0.2 -1.6
Shortness of breath walking on level ground 0.6 0.7 1.0 0.7 -1.0
Qualifications: College or University degree 0.5 1.4 2.9 1.7 -0.0
Eye problems/disorders: None of the above 1.2 1.3 2.6 -1.6 0.3
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.2 0.4 -0.2
Emphysema/chronic bronchitis 0.2 0.2 0.4 -0.6 -0.3
Medication for pain relief, constipation, heartburn 0.1 0.2 0.2 -0.4 0.4
Neck or shoulder pain in last month 0.9 1.3 1.6 -1.3 1.0
Medication: Blood pressure 0.4 0.8 1.3 -1.1 0.4
Angina (self-reported) 1.0 1.3 1.6 -1.0 1.3
Migraine (self-reported) 2.6 3.2 5.2 2.3 -1.1
Medication: Ibuprofen 1.9 2.3 2.4 1.5 -1.5
Medication: Allopurinol 1.3 1.7 3.3 -1.8 0.5
Medication: Omeprazole 0.0 0.0 0.1 0.0 -0.3
Medication: Seretide 50 evohaler 0.0 0.0 0.0 0.1 -0.1
Mean time to correctly identify matches 1.4 2.6 3.6 1.2 -1.9
Heart disease (mother) 1.3 1.6 2.6 -0.8 1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.2 -0.2 0.4
Whole body fat mass 1.4 6.0 7.2 2.2 -2.7
Leg fat mass (right) 0.8 2.9 3.2 1.6 -1.8
Arm predicted mass (right) 1.1 5.6 7.7 -1.9 2.8
Pulse rate, automated reading 0.8 2.6 4.6 0.7 -2.1
Alcohol intake frequency. 0.3 0.8 1.5 0.3 -1.2
Comparative height size at age 10 0.0 0.1 0.2 0.4 0.2
Number of full sisters 3.3 4.1 5.2 -2.3 1.7
Suffer from ‘nerves’ 0.2 0.2 0.3 -0.6 0.4
Overall health rating 0.1 0.3 0.3 -0.5 -0.5
Chest pain or discomfort 0.4 0.6 1.0 -1.0 0.3
Had major operations 1.9 2.3 3.9 2.0 -0.8
Age at last live birth 0.0 0.0 0.1 0.1 -0.2
Family relationship satisfaction 0.1 0.1 0.2 0.2 0.4
Leg pain on walking 0.2 0.3 0.3 -0.6 0.4
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.7 -0.8 0.0
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.2 0.4 0.1
Illness, injury, bereavement, stress in last 2 years 0.0 0.1 0.1 -0.3 -0.0
Medication: Aspirin 0.1 0.2 0.4 -0.6 -0.1
Supplements: Vitamin C 1.3 1.5 2.9 -0.4 1.7
Knee pain experienced in last month 0.1 0.2 0.2 0.4 0.5
Hypertension (Self-reported) 1.1 3.0 4.3 -1.3 2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.2 -0.4 -0.2
Illnesses of father: Heart disease 0.4 0.5 0.8 -0.5 0.9
Illnesses of siblings: Diabetes 0.1 0.1 0.1 -0.2 0.3
Smoking status: Previous 0.2 0.3 0.4 -0.6 0.5
Forced expiratory volume in 1-second (FEV1), predicted 1.5 3.0 3.6 -1.9 1.6
Whole body fat-free mass 1.0 5.7 8.3 -1.8 2.9
Leg fat-free mass (right) 0.5 2.5 3.5 -1.3 1.9
Arm fat percentage (left) 2.4 9.7 10.7 3.0 -3.3
Average weekly red wine intake 1.0 1.4 2.2 -0.8 1.5
Handedness (chirality/laterality): Left-handed 3.8 4.6 5.1 -2.0 2.2
Mood swings 0.4 0.7 1.1 -0.6 1.1
Loneliness, isolation 0.6 0.8 1.6 -1.3 0.2
Long-standing illness, disability or infirmity 0.3 0.5 1.0 -1.0 -0.3
Ever had bowel cancer screening 0.0 0.0 0.1 -0.3 0.0
Diabetes diagnosed by doctor 0.2 0.3 0.5 -0.7 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 6.0 6.4 9.4 3.1 -1.9
Friendships satisfaction 0.7 0.9 1.7 -1.3 -0.2
Qualifications: nursing, teaching 0.3 0.5 0.8 -0.4 0.9
Commuting to job workplace: Walk 2.3 2.4 2.8 1.4 -1.7
Eye problems/disorders: Cataract 3.8 4.4 5.8 2.4 -1.7
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 0.7 -0.9 -0.3
Medication for cholesterol 0.2 0.2 0.5 0.2 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.0 0.0 0.0 -0.2 -0.2
Back pain experienced in last month 1.1 1.7 1.7 1.3 -1.3
Mineral and other dietary supplements 0.1 0.2 0.3 -0.5 0.3
Breast cancer (self-reported) 7.2 8.6 8.8 2.9 -3.0
Asthma (self-reported) 0.3 0.5 1.0 -1.0 0.1
Osteoporosis (self-reported) 0.1 0.2 0.3 -0.5 0.3
Osteoarthritis (self-reported) 0.7 0.9 1.0 -1.0 0.9
Medication: Aspirin 0.1 0.1 0.1 -0.4 -0.0
Medication: Gliclazide 0.7 0.8 0.9 -1.0 0.8
Illnesses of father: None of the above (group 1) 0.8 1.0 1.5 1.2 -0.7
Smoking status: Current 0.2 0.3 0.3 0.5 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.5 0.6 0.8 0.7
Whole body water mass 1.0 5.8 8.3 -1.8 2.9
Leg predicted mass (right) 0.5 2.7 3.8 -1.3 1.9
Arm fat mass (left) 0.8 3.5 3.7 1.8 -1.9
Number of self-reported non-cancer illnesses 1.2 2.0 2.9 -1.0 1.7
Average weekly champagne plus white wine intake 0.6 0.8 1.6 1.3 -0.3
Miserableness 0.0 0.0 0.0 0.0 -0.2
Guilty feelings 0.7 1.0 1.3 1.1 -0.9
Wears glasses or contact lenses 0.3 0.3 0.6 -0.2 -0.8
Ever taken oral contraceptive pill 0.2 0.3 0.5 -0.7 0.1
Hearing aid user 6.6 7.5 8.6 2.9 -2.5
Mother’s age at death 0.2 0.2 0.4 0.6 -0.1
Financial situation satisfaction 0.4 0.5 1.1 -0.1 -1.0
Tinnitus: Yes, now most or all of the time 0.8 0.9 1.3 0.7 -1.2
Commuting to job workplace: Public transport 1.1 1.3 2.2 -0.6 1.5
Eye problems/disorders: Glaucoma 0.6 0.7 1.3 1.1 0.4
Medication: Blood pressure 0.5 1.0 2.0 0.2 1.4
Pain type(s) experienced in last month: Hip pain 0.2 0.2 0.2 -0.5 -0.5
Supplements: Fish oil (including cod liver oil) 0.0 0.0 0.1 -0.1 0.2
High cholesterol (Self-reported) 1.5 2.7 3.0 -1.7 1.6
Medication: Bendroflumethiazide 0.4 0.6 1.1 -0.4 1.1
Medication: Paracetamol 0.9 1.4 1.8 1.0 -1.3
Medication: Lisinopril 0.2 0.2 0.5 0.7 0.1
Medication: Atorvastatin 6.9 8.6 8.7 -3.0 2.9
Illnesses of father: High blood pressure 1.7 2.1 3.6 -0.7 1.9
Alcohol drinker status: Never 0.5 0.6 0.6 -0.7 0.8
Ever smoked 0.1 0.2 0.3 -0.1 0.6
Basal metabolic rate 0.6 3.1 4.5 -1.3 2.1
Leg fat percentage (left) 1.8 6.6 8.8 2.1 -3.0
Arm fat-free mass (left) 0.9 4.7 6.4 -1.7 2.5
Number of operations (self-reported) 4.4 6.5 10.5 3.2 -1.6
Average weekly beer plus cider intake 0.9 1.3 2.3 -1.5 0.5
Irritability 0.0 0.1 0.1 -0.1 -0.4
Risk taking 0.5 0.7 1.1 1.1 -0.5
Ever had prostate specific antigen (PSA) test 0.7 0.9 1.4 0.6 -1.2
Fractured/broken bones in last 5 years 0.0 0.0 0.1 0.1 -0.3
Age started oral contraceptive pill 0.1 0.1 0.2 -0.3 0.5
Diastolic blood pressure, automated reading 1.5 4.6 8.6 2.9 -0.8
Ever depressed for a whole week 1.9 2.3 3.9 2.0 -0.8
Unable to work because of sickness or disability 0.3 0.4 0.8 -0.9 0.1
Commuting to job workplace: Cycle 0.7 0.8 1.6 -0.2 1.3
Myopia 1.5 2.2 2.6 1.3 -1.6
Vascular/heart problems diagnosed by doctor 1.1 2.9 4.3 1.2 -2.1
Cholesterol lowering medication 0.6 0.9 1.2 -0.7 1.1
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.0 0.2 -1.0
Pain experienced in last month 0.6 1.0 1.6 0.6 -1.2
Supplements: Calcium 0.2 0.3 0.4 0.4 -0.6
Basal cell carcinoma (self-reported) 0.6 0.7 0.9 -0.7 0.9
Heart attack/myocardial infarction (self-reported) 1.1 1.5 1.9 1.0 -1.4
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.1 -0.4 0.0
Heart disease (siblings) 0.3 0.4 0.8 -0.9 0.3
Alcohol drinker status: Previous 1.3 1.4 2.9 0.2 -1.7
Pack years of smoking 0.1 0.1 0.1 -0.0 -0.4
Impedance of whole body 2.4 12.4 16.6 2.8 -4.1
Leg fat mass (left) 0.6 2.3 2.8 1.3 -1.7
Arm predicted mass (left) 0.9 4.7 6.3 -1.8 2.5