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chr11:64,721,908-67,294,308

Best TWAS P=7.79e-13 · Best GWAS P=3.92e-12 conditioned to 0.0257

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CFL1	0.04	0.00	bslmm	350	0.02	3.3e-03	-1.224	5.6	2.7e-08	0.64	0.08	0.29	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	-4.020	-5.2	2.4e-07	-0.54	0.99	0.01	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SNX32	0.46	0.36	lasso	8	0.39	1.9e-50	-4.845	-5.6	2.1e-08	-0.47	0.71	0.29	FALSE
4	GTEx	Adipose Visceral Omentum	DPP3	0.16	0.03	enet	17	0.05	8.3e-04	3.722	-5.6	2.4e-08	-0.30	0.07	0.38	FALSE
5	GTEx	Adrenal Gland	FIBP	0.20	0.02	enet	14	0.13	2.3e-05	0.096	-6.3	2.3e-10	-0.70	0.02	0.88	FALSE
6	GTEx	Artery Coronary	FIBP	0.13	0.01	lasso	5	0.04	1.3e-02	-3.755	-5.2	1.6e-07	-0.75	0.13	0.34	FALSE
7	GTEx	Artery Coronary	RNASEH2C	0.16	0.08	lasso	4	0.07	2.2e-03	-6.547	5.8	5.8e-09	0.32	0.04	0.88	FALSE
8	GTEx	Artery Tibial	EFEMP2	0.11	0.07	lasso	8	0.05	1.3e-04	6.940	-5.8	8.9e-09	-0.94	0.01	0.99	FALSE
9	GTEx	Artery Tibial	BANF1	0.05	0.05	lasso	5	0.06	3.4e-05	-6.327	5.7	9.7e-09	0.84	0.13	0.74	FALSE
10	GTEx	Brain Cerebellar Hemisphere	EFEMP2	0.35	0.15	enet	5	0.09	2.2e-03	-6.243	-6.2	6.6e-10	-0.88	0.07	0.81	FALSE
11	GTEx	Brain Cerebellum	EFEMP2	0.45	0.40	enet	8	0.39	1.6e-12	-6.095	-5.8	5.4e-09	-0.86	0.21	0.79	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	FIBP	0.40	0.21	enet	26	0.29	4.3e-10	-3.834	-5.7	1.1e-08	-0.62	0.86	0.13	FALSE
13	GTEx	Cells Transformed fibroblasts	EFEMP2	0.06	0.06	lasso	3	0.07	7.8e-06	-5.413	-5.3	1.0e-07	-0.80	0.08	0.91	FALSE
14	GTEx	Cells Transformed fibroblasts	CFL1	0.06	0.02	enet	12	0.01	1.1e-01	-5.293	5.3	9.0e-08	0.64	0.26	0.44	FALSE
15	GTEx	Colon Sigmoid	CTSW	0.11	0.06	lasso	3	0.07	1.4e-03	-6.095	6.2	7.2e-10	0.86	0.16	0.37	FALSE
16	GTEx	Esophagus Muscularis	FIBP	0.11	0.04	lasso	4	0.04	1.2e-03	-5.317	-5.6	2.6e-08	-0.63	0.19	0.73	FALSE
17	GTEx	Liver	CTSW	0.27	0.03	lasso	13	0.02	1.0e-01	-4.020	5.7	1.5e-08	0.72	0.05	0.29	FALSE
18	GTEx	Nerve Tibial	SIPA1	0.17	0.01	enet	19	0.06	6.8e-05	3.970	-5.2	2.5e-07	-0.28	0.30	0.10	FALSE
19	GTEx	Spleen	CTD-3074O7.5	0.29	0.03	enet	27	0.05	2.6e-02	3.747	-5.6	2.3e-08	-0.39	0.01	0.06	FALSE
20	METSIM	Adipose	EFEMP2	0.07	0.05	lasso	8	0.04	4.2e-06	-6.154	-7.1	1.1e-12	-0.85	0.04	0.96	FALSE
21	METSIM	Adipose	FIBP	0.05	0.02	blup	344	0.02	1.0e-03	-3.834	-5.4	6.6e-08	-0.52	0.92	0.04	FALSE
22	METSIM	Adipose	SNX32	0.17	0.13	lasso	4	0.16	3.7e-23	-4.660	-5.5	3.6e-08	-0.50	0.87	0.13	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	EFEMP2	0.08	0.09	enet	13	0.09	6.8e-12	5.855	-6.2	6.1e-10	-0.86	0.03	0.97	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	C11orf80	0.36	0.13	enet	32	0.20	1.3e-24	-3.939	5.2	2.3e-07	0.16	0.07	0.74	TRUE
25	YFS	Blood	MUS81	0.04	0.02	blup	348	0.04	6.3e-12	-6.095	6.0	1.8e-09	0.78	0.29	0.71	FALSE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SNX32	0.05	0.05	blup	60	0.03	1.1e-03	-4.845	-5.6	2.3e-08	-0.64	0.48	0.17	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	EFEMP2	0.04	0.02	lasso	5	0.02	1.4e-05	-6.058	-6.1	1.0e-09	-0.86	0.04	0.95	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	FIBP	0.03	0.03	blup	45	0.03	2.6e-07	-6.058	-5.8	6.8e-09	-0.80	0.03	0.97	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	SNX32	0.11	0.08	enet	5	0.07	9.7e-05	-6.078	-5.5	4.1e-08	-0.46	0.39	0.49	FALSE
30	The Cancer Genome Atlas	Glioblastoma Multiforme	CTSW	0.16	0.18	enet	16	0.19	2.3e-06	-4.561	5.5	3.6e-08	0.74	0.09	0.81	FALSE
31	The Cancer Genome Atlas	Glioblastoma Multiforme	SNX32	0.13	0.05	blup	60	0.09	1.1e-03	-4.845	-6.1	8.3e-10	-0.77	0.06	0.56	FALSE
32	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNX32	0.15	0.14	enet	8	0.15	2.5e-16	-4.660	-5.9	3.7e-09	-0.54	0.97	0.03	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SNX32	0.15	0.11	blup	60	0.15	6.0e-17	-4.845	-5.5	3.9e-08	-0.44	0.96	0.04	FALSE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DKFZp761E198	0.11	0.02	blup	39	0.03	4.6e-03	-6.469	-7.2	7.8e-13	-0.61	0.02	0.69	TRUE
35	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FIBP	0.05	0.01	blup	44	0.02	1.5e-02	-4.845	-5.4	8.5e-08	-0.64	0.05	0.20	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFEMP2	0.01	0.00	blup	45	0.01	3.0e-02	-4.660	-6.1	1.1e-09	-0.75	0.03	0.39	FALSE
37	The Cancer Genome Atlas	Brain Lower Grade Glioma	OVOL1	0.03	0.03	blup	36	0.02	8.3e-04	2.008	5.3	1.4e-07	0.59	0.09	0.47	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNX32	0.15	0.27	enet	23	0.26	6.1e-30	-4.845	-5.1	3.0e-07	-0.55	1.00	0.00	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	FIBP	0.02	0.01	blup	45	0.02	1.3e-03	-3.740	-5.8	9.0e-09	-0.72	0.08	0.34	FALSE
40	The Cancer Genome Atlas	Lung Adenocarcinoma	SNX32	0.14	0.09	blup	60	0.13	8.8e-15	-4.845	-5.5	3.7e-08	-0.46	0.94	0.06	FALSE
41	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SNX32	0.22	0.21	enet	16	0.24	6.2e-27	-4.845	-5.8	6.8e-09	-0.54	0.88	0.12	FALSE
42	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SNX32	0.08	0.10	blup	60	0.11	6.0e-08	-4.845	-6.0	2.5e-09	-0.62	0.96	0.03	FALSE
43	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SNX32	0.40	0.17	blup	60	0.22	1.3e-09	-4.660	-6.4	1.9e-10	-0.71	0.18	0.82	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	SNX32	0.07	0.08	lasso	4	0.10	2.0e-10	-4.020	-5.2	2.6e-07	-0.49	0.92	0.08	FALSE
45	The Cancer Genome Atlas	Soft Tissue Sarcoma	SNX32	0.08	0.08	lasso	2	0.10	1.5e-06	-5.413	-5.5	4.6e-08	-0.75	0.44	0.52	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	SNX32	0.23	0.26	lasso	7	0.25	6.4e-24	-4.845	-5.2	1.7e-07	-0.50	1.00	0.00	FALSE