[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr16:49,488,151-51,535,063

Best TWAS P=3.22e-46 · Best GWAS P=3.24e-61 conditioned to 1.27e-86

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Lung Adenocarcinoma	NOD2	0.07	0.01	lasso	4	0.02	1.1e-03	16.5	14.3	3.2e-46	0.78	0.00	0.91	TRUE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	CYLD	0.03	0.00	blup	69	0.02	3.8e-03	-9.4	13.5	2.5e-41	0.60	0.11	0.66	TRUE
2	GTEx	Esophagus Mucosa	CYLD	0.13	0.06	enet	10	0.06	7.0e-05	-9.4	13.2	1.7e-39	0.72	0.06	0.93	TRUE
5	GTEx	Skin Not Sun Exposed Suprapubic	NOD2	0.15	0.06	lasso	4	0.02	1.9e-02	-9.6	9.7	3.0e-22	0.46	0.54	0.24	TRUE
6	GTEx	Testis	NKD1	0.24	0.13	lasso	4	0.14	8.1e-07	6.9	8.3	7.4e-17	0.10	0.76	0.01	TRUE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	CYLD	0.03	0.03	enet	7	0.02	9.3e-04	-9.4	7.1	1.6e-12	0.29	0.26	0.04	TRUE
1	CommonMind	Brain Pre-frontal Cortex	ADCY7	0.10	0.02	enet	23	0.05	7.8e-07	-2.9	5.9	2.9e-09	0.02	0.60	0.02	TRUE
7	METSIM	Adipose	ADCY7	0.04	0.00	enet	22	0.01	1.7e-02	1.0	-5.3	1.3e-07	-0.03	0.20	0.04	TRUE
3	GTEx	Esophagus Mucosa	NOD2	0.19	0.14	lasso	7	0.15	4.1e-10	-9.5	10.2	3.1e-24	0.46	0.99	0.01	FALSE
4	GTEx	Nerve Tibial	CYLD	0.10	0.00	lasso	6	0.00	1.7e-01	7.3	7.4	1.7e-13	0.37	0.10	0.05	FALSE
8	YFS	Blood	PAPD5	0.03	0.01	enet	13	0.02	1.4e-07	-4.7	-6.0	1.8e-09	0.02	0.96	0.00	FALSE