[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr16:49,488,151-51,535,063

Best TWAS P=3.22e-46 · Best GWAS P=3.24e-61 conditioned to 1.27e-86

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADCY7 0.10 0.02 enet 23 0.05 7.8e-07 -2.9 5.9 2.9e-09 0.02 0.60 0.02 TRUE
2 GTEx Esophagus Mucosa CYLD 0.13 0.06 enet 10 0.06 7.0e-05 -9.4 13.2 1.7e-39 0.72 0.06 0.93 TRUE
3 GTEx Esophagus Mucosa NOD2 0.19 0.14 lasso 7 0.15 4.1e-10 -9.5 10.2 3.1e-24 0.46 0.99 0.01 FALSE
4 GTEx Nerve Tibial CYLD 0.10 0.00 lasso 6 0.00 1.7e-01 7.3 7.4 1.7e-13 0.37 0.10 0.05 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic NOD2 0.15 0.06 lasso 4 0.02 1.9e-02 -9.6 9.7 3.0e-22 0.46 0.54 0.24 TRUE
6 GTEx Testis NKD1 0.24 0.13 lasso 4 0.14 8.1e-07 6.9 8.3 7.4e-17 0.10 0.76 0.01 TRUE
7 METSIM Adipose ADCY7 0.04 0.00 enet 22 0.01 1.7e-02 1.0 -5.3 1.3e-07 -0.03 0.20 0.04 TRUE
8 YFS Blood PAPD5 0.03 0.01 enet 13 0.02 1.4e-07 -4.7 -6.0 1.8e-09 0.02 0.96 0.00 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma CYLD 0.03 0.03 enet 7 0.02 9.3e-04 -9.4 7.1 1.6e-12 0.29 0.26 0.04 TRUE
10 The Cancer Genome Atlas Lung Adenocarcinoma CYLD 0.03 0.00 blup 69 0.02 3.8e-03 -9.4 13.5 2.5e-41 0.60 0.11 0.66 TRUE
11 The Cancer Genome Atlas Lung Adenocarcinoma NOD2 0.07 0.01 lasso 4 0.02 1.1e-03 16.5 14.3 3.2e-46 0.78 0.00 0.91 TRUE