[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr10:93,353,083-95,513,408

Best TWAS P=6.03e-56 · Best GWAS P=3.31e-52 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MARCH5 0.09 0.07 blup 335 0.08 9.5e-10 -1.3 5.2 1.6e-07 0.00 1.00 0.00 FALSE
2 GTEx Breast Mammary Tissue (Female) MARCH5 0.15 0.03 enet 20 0.08 1.7e-03 -3.8 -6.2 6.3e-10 0.27 0.12 0.06 TRUE
3 GTEx Esophagus Muscularis EIF2S2P3 0.09 0.04 lasso 6 0.04 1.1e-03 11.7 9.8 6.8e-23 -0.78 0.03 0.88 TRUE
4 GTEx Nerve Tibial EXOC6 0.19 0.00 enet 39 0.05 2.6e-04 8.7 -8.9 5.5e-19 0.22 0.09 0.04 FALSE
5 GTEx Prostate EIF2S2P3 0.21 0.05 lasso 4 0.11 1.1e-03 11.7 12.3 7.7e-35 -0.69 0.05 0.38 FALSE
6 GTEx Spleen EIF2S2P3 0.32 0.04 enet 15 0.11 1.2e-03 9.8 12.3 8.5e-35 -0.76 0.02 0.75 TRUE
7 GTEx Testis HHEX 0.11 0.02 enet 8 0.00 4.2e-01 14.9 15.0 7.3e-51 -0.86 0.01 0.90 TRUE
8 GTEx Thyroid EIF2S2P3 0.15 0.14 lasso 2 0.14 6.2e-11 11.7 11.8 3.8e-32 -0.85 0.98 0.02 FALSE
9 GTEx Whole Blood EIF2S2P3 0.10 0.02 lasso 6 0.05 2.2e-05 11.7 8.3 7.6e-17 -0.58 0.17 0.82 TRUE
10 NTR Blood KIF11 0.11 0.10 lasso 8 0.10 3.0e-29 -13.5 14.2 6.3e-46 -0.91 1.00 0.00 TRUE
11 ROSMAP Brain Pre-frontal Cortex EIF2S2P3 0.05 0.01 bslmm 378 0.03 2.7e-04 -8.3 14.2 6.8e-46 -0.52 0.04 0.64 TRUE
12 YFS Blood HHEX 0.09 0.04 lasso 9 0.08 2.3e-25 14.9 15.8 6.0e-56 -0.66 0.01 0.99 TRUE
13 The Cancer Genome Atlas Brain Lower Grade Glioma CYP26A1 0.07 0.02 enet 7 0.03 2.8e-04 8.4 -5.8 5.9e-09 0.07 0.02 0.54 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma CYP26C1 0.16 0.09 enet 7 0.14 1.8e-15 8.9 -5.8 8.9e-09 0.11 0.61 0.39 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HHEX 0.03 0.00 blup 28 0.02 1.4e-03 7.3 13.4 8.8e-41 -0.84 0.00 0.53 TRUE