Hub : Genes

FRAT1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0480	0.0180	3.3e-04	0.007	0.024	0.015	0.025	0.007	4.2e-02	6.1e-04	5.5e-03	4.9e-04	4.4e-02
2	GTEx	Cells Transformed fibroblasts	0.0750	0.0330	4.9e-03	0.045	NA	0.042	NA	0.046	2.6e-04	NA	4.2e-04	NA	2.3e-04
3	GTEx	Skin Sun Exposed Lower leg	0.1480	0.0560	2.1e-03	0.008	NA	0.008	NA	0.009	6.6e-02	NA	6.9e-02	NA	5.6e-02
4	METSIM	Adipose	0.0582	0.0217	3.5e-05	0.030	0.025	0.018	0.020	0.030	2.4e-05	1.1e-04	9.0e-04	4.7e-04	2.2e-05
5	NTR	Blood	0.0493	0.0126	3.6e-13	0.034	0.043	0.049	0.045	0.052	3.7e-11	9.3e-14	1.7e-15	3.3e-14	3.2e-16
6	YFS	Blood	0.1984	0.0256	0.0e+00	0.190	0.230	0.249	0.243	0.244	8.2e-60	5.6e-74	1.5e-80	1.9e-78	7.5e-79
7	TCGA	Bladder Urothelial Carcinoma	0.0730	0.0430	8.5e-03	0.021	0.036	0.031	NA	0.024	6.7e-03	4.9e-04	1.1e-03	NA	3.9e-03
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0555	0.0353	6.5e-04	0.014	0.022	0.007	NA	0.009	8.1e-03	1.3e-03	4.5e-02	NA	2.8e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	3.7	5.8	12.0	-2.6	-3.3	-0.7	-3.5	-3.4	-0.6	-0.6	-2.2
Bipolar Disorder or Schizophrenia	3.0	7.2	15.3	-3.5	-3.7	-0.4	-3.9	-3.7	-0.3	0.4	-1.7
Depressed Affect (Nagel 2018)	0.3	0.7	2.5	0.4	1.0	-1.6	0.6	0.3	-1.2	-0.5	-0.2
Depression (Nagel 2018)	0.1	0.1	0.2	-0.3	0.5	0.2	0.1	0.2	-0.1	0.2	0.4
Intelligence (Savage-Jansen 2018)	1.7	5.3	12.3	-2.0	-3.4	-0.4	-1.8	-3.5	-0.8	-0.9	-3.1
Neuroticism (Nagel 2018)	1.7	4.0	13.2	1.5	3.6	-2.1	1.7	1.6	-1.6	-0.0	2.1
Schizophrenia (2018)	1.2	2.5	5.6	-2.4	-2.1	0.0	-2.2	-2.0	0.1	1.0	-0.4
Schizophrenia vs Biploar Disorder	1.1	1.4	4.8	0.1	0.6	0.2	0.7	1.0	1.4	1.6	2.2
Worry (Nagel 2018)	2.4	5.1	11.8	1.6	3.4	-1.2	1.8	2.6	0.2	2.1	3.3
Alzheimer’s Disease (in mother)	1.5	1.7	3.4	-1.4	-1.1	-0.4	-0.9	-1.9	-1.6	-1.4	-1.3
Alzheimer’s Disease (in father)	2.9	3.1	8.2	-2.2	-2.9	0.7	-2.2	-1.4	1.0	0.4	-1.8
Alzheimer’s Disease (including proxy)	2.8	4.0	8.2	-2.8	-2.4	0.0	-2.4	-2.9	-1.0	-1.0	-1.6
Crohns Disease (2017)	0.7	1.6	4.0	-1.7	0.6	-1.1	-2.0	-0.8	-1.4	-0.7	1.0
Irritable Bowel Disease (IBD)	0.4	1.0	2.7	-1.0	0.5	-1.2	-1.6	-0.2	-0.8	-0.7	1.0
Ulcerative Colitis (UC)	0.2	0.4	1.3	-0.1	0.2	-0.8	-1.2	0.3	0.3	0.2	1.1
Major Depression (MDD)	2.4	2.9	8.4	-1.0	-2.9	-0.8	-0.6	-0.6	1.5	1.6	-2.7
Reaction Time	0.7	1.4	4.7	-2.2	-1.1	-0.2	-1.8	-0.8	0.6	0.7	-0.2
Verbal and Numeric Reasoning (VNR)	2.3	5.5	15.6	-2.4	-4.0	0.2	-2.3	-3.2	0.3	0.5	-2.6
Breast Cancer	0.6	1.5	3.1	1.7	0.9	-1.0	1.0	1.1	1.0	1.1	1.8
Ovarian Cancer	0.3	0.4	1.1	-0.5	-0.1	-0.1	-0.6	-0.9	-1.1	-0.7	0.2
Prostate Cancer	0.5	0.6	1.5	1.1	0.8	-0.6	0.6	1.0	1.2	-0.0	0.6
Age at First Birth	0.4	0.6	2.6	-0.1	-1.1	-0.1	0.0	0.4	1.0	1.6	-0.2
Bipolar Disorder (2011)	4.3	4.1	10.2	-2.3	-1.6	-1.2	-3.1	-3.2	-1.6	-0.8	-0.9
Body Mass Index (BMI) (2010)	1.3	1.8	5.0	-0.1	-1.0	2.2	1.3	0.8	1.2	-0.2	-2.2
Coronary Artery Disease (CAD)	1.1	1.3	3.7	-1.1	-1.3	1.9	-1.1	-0.5	1.1	-0.1	-1.2
Crohns Disease (2012)	0.3	0.5	1.3	-1.1	-0.1	0.5	-1.0	-0.8	-0.9	-0.5	0.3
Mean Putamen Volume	0.4	0.4	1.2	-1.1	0.1	-0.9	-0.6	-0.8	-0.5	-0.4	0.3
Fasting Glucose	1.7	2.0	5.9	-1.2	-2.4	0.8	-1.4	-0.6	1.5	0.8	-1.7
HbA1C	0.7	0.8	2.5	-1.3	-1.6	0.0	-0.5	-0.9	0.1	0.2	-1.0
HDL Cholesterol	0.3	0.5	1.5	0.6	0.8	1.2	0.0	0.3	-0.0	-0.1	1.2
LDL Cholesterol	0.6	1.0	2.3	-1.2	-0.7	-0.9	-1.5	-1.4	-1.0	-0.4	-0.4
Lupus	1.7	2.5	6.1	-1.5	-0.9	-0.8	-2.1	-2.5	-2.4	-0.3	-0.2
Neuroticism (2016)	1.6	2.4	7.8	0.6	2.1	-2.8	0.6	1.1	-0.5	1.0	1.9
Primary Biliary Cirrhosis	2.1	2.9	8.8	-1.0	0.4	-1.4	-1.8	-2.2	-3.0	-1.8	-0.3
Rheumatoid Arthritis	2.0	2.8	9.6	1.4	2.8	-0.8	0.1	1.5	-0.4	-0.4	3.1
Schizophrenia (2014)	1.1	2.4	5.0	-2.2	-2.1	0.3	-2.2	-1.9	0.3	0.8	-0.2
Triglycerides	1.1	1.7	3.3	-1.4	-1.6	-0.4	-1.8	-1.8	-0.8	-0.0	-1.5
Type 2 Diabetes (T2D) (2012)	1.5	1.7	3.5	-1.9	-1.8	-1.1	-1.7	-1.2	-0.0	0.3	-1.1
Ulcerative Colitis	0.5	0.7	1.7	1.1	0.6	0.4	0.8	1.3	0.9	0.4	0.9
Blood Eosinophil Count	2.2	16.7	38.2	4.8	6.2	-0.2	5.3	5.5	0.8	0.3	3.7
Blood Platelet Count	1.0	11.0	34.6	3.2	1.1	1.3	5.9	4.7	3.2	2.6	-0.8
Blood Red Count	0.3	2.5	6.3	-1.8	-2.2	-2.0	-0.6	-1.1	0.5	0.3	-2.5
Blood White Count	20.6	152.5	324.0	15.4	18.0	-1.6	14.0	16.5	3.9	3.0	12.8
Heel T-Score	0.2	1.3	7.9	-2.8	-1.4	0.4	-0.2	-0.5	0.3	0.1	-0.4
BMI	2.0	11.5	29.1	-3.7	-5.0	0.4	-2.1	-4.0	-0.8	-1.7	-5.4
Height	0.2	3.5	14.1	3.8	2.9	-0.5	1.1	1.4	-0.7	-1.3	0.6
Waist Hip Ratio (WHR)	0.3	1.5	7.8	0.3	-0.4	-2.8	1.3	-0.1	-0.0	0.2	-1.5
Systolic Blood Pressure	0.5	2.7	8.9	-0.5	-1.1	0.0	-0.7	1.0	2.6	3.0	1.7
Smoking Status	0.2	0.6	2.7	-0.1	-0.5	0.1	-0.2	-0.5	-0.8	-0.8	-1.6
Allergy or Eczema	0.8	2.0	5.0	0.7	-0.3	1.2	2.2	1.9	2.1	0.1	-1.1
Cardiovascular Disease	0.3	0.9	3.5	-0.3	-1.1	0.1	-0.4	0.4	1.9	1.5	-0.1
Hypothyroidism (self reported)	0.1	0.3	0.8	-0.4	-0.9	0.7	-0.2	-0.8	-0.3	0.0	-0.6
Respiratory disease	1.3	2.9	7.3	0.1	-2.2	1.7	0.8	0.2	2.7	0.6	-2.6
Type 2 Diabetes (T2D) (2018)	1.8	3.3	9.1	-2.5	-3.0	-0.1	-1.0	-2.0	0.3	0.5	-2.4
Lung FEV1/FVC ratio	0.1	0.7	2.8	-0.1	-1.7	-0.7	0.0	-0.5	0.5	0.6	-1.3
Lung FVC	1.6	7.9	14.6	-3.8	-3.7	-0.1	-2.0	-3.6	-1.4	-1.3	-3.7
Neuroticism	1.6	4.0	9.6	1.7	3.1	-2.7	0.9	1.4	-1.1	0.7	2.7
Chronotype (morning person)	0.5	1.2	3.6	1.2	1.9	0.5	1.0	0.8	-1.3	-0.5	0.8
Hair Pigment	0.0	0.7	2.5	0.2	1.6	0.0	0.7	1.2	0.3	0.1	1.0
Tanning	0.1	1.1	5.3	-0.5	-0.9	-0.7	0.7	-0.2	-0.2	-1.2	-2.3
Hand grip strength (left)	4.7	12.5	30.2	-3.0	-3.9	1.4	-1.6	-4.0	-2.7	-4.2	-5.5
Number of treatments/medications taken	1.5	2.7	7.1	1.5	0.3	-0.4	1.6	2.0	2.7	2.1	0.9
Average weekly spirits intake	0.2	0.3	0.8	-0.9	-0.2	-0.2	-0.5	-0.5	-0.3	0.5	0.7
Sensitivity / hurt feelings	1.5	2.5	6.3	1.4	2.3	-2.1	-0.1	-0.3	-2.5	-0.9	0.9
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.5	-0.1	0.3	-0.1	-0.2	-0.2	-0.7	-0.2	-0.3
Hearing difficulty/problems: Yes	1.8	2.7	6.7	-1.3	-1.8	0.3	-1.4	-2.6	-1.6	-1.5	-1.9
Relative age of first facial hair	1.7	3.5	15.0	-0.4	-2.5	1.9	1.1	-0.1	1.2	-0.3	-3.9
Other serious medical condition/disability diagnosed by doctor	1.7	2.3	7.5	-1.6	-2.0	1.0	-0.3	-1.4	-0.3	-0.9	-2.7
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.4	-0.3	-1.8	-2.1	0.5	-0.4	0.8	1.6	-1.3
Ever had hysterectomy (womb removed)	0.3	0.4	1.1	-0.5	-1.0	0.1	0.2	-0.1	1.1	0.4	-0.6
Systolic blood pressure, automated reading	0.3	1.0	3.1	-1.1	-1.0	-1.3	-0.4	-0.2	0.7	1.8	0.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.0	-0.1	0.4	-1.4	0.0	0.7	0.8	1.3	1.4
Angina	0.6	0.8	2.1	-1.0	-0.2	0.5	-0.2	0.5	1.2	1.5	1.1
Medication for hormone replacement therapy	0.5	0.6	1.7	-0.3	-1.1	-0.6	-0.4	-0.8	-0.3	-0.3	-1.3
Vitamin and mineral supplements	0.9	1.2	3.9	-2.0	-1.2	-0.7	-1.1	-1.2	0.1	0.6	-0.7
Supplements: Zinc	0.1	0.1	0.3	0.6	-0.2	0.2	-0.4	-0.3	-0.5	-0.1	0.2
Medication: Co-codamol	0.6	0.7	2.4	-0.7	-1.1	0.2	0.7	-0.6	-0.2	-0.8	-1.6
Medication: Metformin	0.9	1.3	3.0	-0.8	-1.7	-0.9	-1.0	-1.6	0.3	0.4	-1.3
Diabetes (father)	0.3	0.3	0.9	-0.2	-0.6	-0.7	-0.6	-0.4	0.4	0.9	-0.3
Diabetes (mother)	2.2	2.8	7.8	-2.1	-2.8	-1.3	-1.6	-1.7	0.6	0.8	-1.6
Severe depression (siblings)	3.8	4.2	14.8	-2.1	-3.4	0.8	-0.6	-1.2	0.3	-0.5	-3.8
Pack years adult smoking proportion	1.1	1.6	4.5	-0.6	-1.0	2.1	1.3	1.4	1.6	0.6	-0.9
Impedance of leg (right)	0.7	3.6	6.2	1.9	2.1	-2.5	0.5	1.9	0.8	2.0	2.3
Leg fat-free mass (left)	0.4	2.2	5.6	-0.3	-1.3	2.2	-0.1	-1.2	-0.7	-1.9	-2.4
Trunk fat percentage	0.4	1.5	4.6	-0.9	-2.1	-0.5	-0.1	-0.9	0.7	0.6	-2.1
Hand grip strength (right)	3.9	10.5	28.9	-2.4	-4.0	2.0	-1.3	-3.4	-1.9	-3.6	-5.4
Townsend deprivation index at recruitment	0.1	0.1	0.4	-0.3	-0.3	0.2	0.2	0.5	0.6	0.2	-0.4
Current tobacco smoking	0.8	1.3	4.3	-0.6	-1.3	2.1	-0.5	0.1	0.9	0.1	-1.7
Average weekly fortified wine intake	2.1	2.4	8.0	1.0	-0.0	2.8	1.4	1.9	2.2	0.3	-0.2
Maternal smoking around birth	0.8	1.2	3.1	-1.8	-1.4	-0.3	-1.6	-1.1	0.0	-0.2	-0.9
Fed-up feelings	0.2	0.3	0.7	-0.2	0.7	-0.8	-0.7	0.0	-0.6	0.1	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.3	-0.0	0.8	0.3	-0.1	0.8	0.7	0.7	1.1
Relative age voice broke	0.1	0.2	0.6	0.5	-0.1	0.4	0.5	0.5	0.2	-0.1	-0.8
Taking other prescription medications	0.8	1.2	4.2	0.5	-0.7	-0.0	1.4	0.8	2.1	1.2	-0.7
Age when periods started (menarche)	0.2	0.6	2.2	-0.4	-0.5	-0.1	-1.5	-1.1	-0.2	-0.1	-0.8
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	5.6	-0.2	-1.3	-1.3	1.8	1.1	2.4	1.7	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	3.6	-1.8	-1.9	-0.5	-0.7	-1.9	-0.7	-0.4	-1.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.9	1.0	-0.1	-0.9	-0.3	-0.2	-0.0	0.7	-0.0
Qualifications: CSEs or equivalent	1.7	2.3	4.3	1.5	1.8	0.2	1.3	2.0	1.1	1.2	2.1
Serious illness, injury or assault to yourself	1.0	1.2	3.5	-0.1	-1.9	0.3	0.7	0.1	1.5	0.4	-1.8
High blood pressure	0.3	0.7	2.3	-0.3	-0.1	-0.0	-0.5	0.6	1.4	1.5	0.9
Hayfever, allergic rhinitis or eczema	1.2	2.6	6.1	0.8	-1.1	0.9	2.2	1.9	2.5	0.9	-1.7
Multivitamins +/- minerals	1.1	1.4	2.9	1.7	1.2	1.7	1.0	1.1	-0.2	-0.8	0.8
Stomach or abdominal pain in last month	2.2	2.8	7.4	0.2	-1.9	1.7	1.2	1.4	2.7	1.6	-1.6
Supplements: Glucosamine	0.4	0.5	1.4	-0.6	-0.3	-0.3	-0.8	-1.1	-1.2	-0.3	-0.3
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.2	-0.0	0.7	-1.1	0.4	1.0	0.7	1.8	1.5
Medication: Atenolol	1.2	1.4	6.3	0.1	2.0	0.2	-0.0	1.1	0.3	0.3	2.5
Medication: Levothyroxine sodium	0.2	0.4	1.7	0.4	0.3	1.3	0.7	0.1	-0.8	-0.3	0.3
Sitting height	0.1	0.5	1.6	1.2	0.7	0.4	-0.4	0.3	-0.1	-1.3	-0.2
Chronic bronchitis/emphysema (father)	0.8	0.9	2.3	-0.5	-1.3	0.6	0.2	0.3	1.5	1.5	-0.7
High blood pressure (mother)	0.4	0.6	1.6	0.3	0.2	-0.9	0.1	0.6	0.6	1.3	1.1
Body mass index (BMI)	1.1	4.8	11.8	-2.6	-3.4	0.8	-1.3	-2.6	-0.3	-0.7	-3.2
Impedance of leg (left)	0.5	2.6	7.4	1.4	1.8	-2.7	0.2	1.4	0.5	1.5	1.9
Leg predicted mass (left)	0.4	2.3	5.8	-0.3	-1.3	2.2	-0.2	-1.3	-0.8	-1.9	-2.4
Trunk fat mass	0.4	1.9	7.5	-1.0	-2.2	0.1	-0.2	-1.3	0.2	-0.2	-2.7
Waist circumference	0.7	2.7	6.8	-1.6	-2.1	-1.1	-0.6	-2.2	-1.1	-0.9	-2.6
Number of incorrect matches in round	0.2	0.4	0.8	-0.5	-0.7	0.6	0.2	-0.1	0.8	0.8	-0.9
Past tobacco smoking	0.7	1.3	4.0	-0.2	-0.2	1.6	-0.7	0.8	2.0	1.3	1.1
Alcohol usually taken with meals	1.1	1.7	4.4	0.1	-1.9	-1.2	-1.1	-2.1	-0.6	-0.2	-1.7
Nervous feelings	4.6	8.6	19.9	3.2	4.5	-0.5	2.4	3.8	1.1	2.0	3.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.6	-0.0	0.7	-0.6	0.8	0.7	-0.1	0.0	0.2
Hearing difficulty/problems with background noise	1.9	3.1	7.0	-1.5	-2.2	0.4	-2.1	-2.7	-0.9	-1.0	-2.0
Hair/balding pattern: Pattern 2	0.4	0.5	1.5	-0.5	-0.4	-0.3	0.2	-0.7	-0.5	-1.2	-1.0
Had menopause	0.9	1.1	4.8	-0.6	-1.2	-0.7	-0.2	-0.1	1.3	2.2	0.2
Had other major operations	1.4	1.7	4.1	-1.5	-1.4	0.7	-1.4	-2.0	-1.1	-0.8	-1.0
Forced vital capacity (FVC)	0.9	3.6	10.2	-0.9	-1.4	0.9	-0.5	-1.9	-1.8	-2.8	-3.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	2.5	-1.4	-1.3	0.4	-1.0	-1.6	-0.6	-0.8	-1.1
Ever unenthusiastic/disinterested for a whole week	0.9	1.2	2.9	-1.7	-1.7	-0.5	-0.8	-1.1	0.3	-0.0	-1.2
Qualifications: None of the above	1.4	3.0	7.6	1.7	1.5	-1.0	2.8	2.5	1.4	1.4	0.5
Financial difficulties in last 2 years	1.1	1.4	5.2	-1.2	-2.3	0.3	-0.4	-0.4	1.0	1.8	-0.4
Mouth/teeth dental problems	0.1	0.2	0.6	-0.1	-0.1	-0.4	0.7	0.4	0.2	-0.8	-0.5
Heart attack	0.5	0.6	2.7	-1.6	-0.4	1.3	-0.3	-0.1	0.2	-0.6	-0.2
Allergy	1.3	3.0	8.7	-1.0	1.3	-0.8	-2.0	-1.6	-2.9	-1.2	1.9
Pain all over the body in last month	0.5	0.5	1.8	0.0	0.5	0.0	0.5	1.0	0.8	1.4	0.6
Diabetes (self-reported)	0.6	1.0	2.2	-0.7	-1.2	-1.5	0.2	-0.4	1.0	1.2	-0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.3	-0.3	-0.2	0.5	1.2	0.9	0.5	-0.2	-0.2
Medication: Ramipril	0.4	0.5	1.5	-0.9	-0.8	0.1	0.7	0.2	0.5	0.4	-1.2
Medication: Simvastatin	0.7	1.0	2.4	-1.4	-1.6	-0.6	-0.2	-0.9	0.7	0.6	-1.2
Fluid intelligence score	4.3	8.9	20.3	-3.1	-4.5	1.2	-3.2	-4.2	-0.6	-0.5	-3.3
Illnesses of siblings	1.4	2.0	6.1	1.7	2.5	1.1	0.2	0.7	-0.2	-0.6	2.2
Neuroticism score	1.2	2.5	6.8	0.8	2.6	-2.1	-0.3	0.8	-1.1	0.7	2.4
Weight	0.7	3.5	10.0	-1.4	-2.3	1.2	-0.8	-2.2	-1.0	-1.8	-3.2
Impedance of arm (right)	2.0	9.5	16.8	3.6	4.1	-2.2	2.4	3.8	1.0	2.0	4.1
Arm fat percentage (right)	0.4	1.8	5.2	-1.5	-2.3	-0.3	-0.2	-1.4	0.1	-0.1	-2.2
Trunk fat-free mass	0.6	3.4	7.6	-0.6	-1.5	1.8	-1.0	-2.1	-1.5	-2.5	-2.8
Hip circumference	0.2	1.0	1.8	-0.8	-0.9	0.5	-0.7	-1.3	-1.1	-1.0	-1.3
Time employed in main current job	0.9	1.1	3.5	0.7	1.9	0.1	0.5	1.2	-0.3	0.0	1.7
Alcohol intake versus 10 years previously	0.2	0.3	0.6	-0.7	-0.3	-0.6	-0.7	-0.5	0.1	0.5	0.1
Father’s age at death	0.5	0.6	3.2	1.8	0.1	-0.9	0.7	0.5	0.4	0.5	-0.3
Worrier / anxious feelings	1.6	3.0	12.4	-0.2	2.9	-0.7	-0.8	0.7	-1.0	0.9	3.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.1	-1.4	-1.4	0.2	-0.6	-1.3	-0.3	0.9	-0.6
Falls in the last year	0.5	0.6	3.1	-0.1	-0.3	0.5	0.3	0.8	0.8	1.8	0.3
Hair/balding pattern: Pattern 3	0.7	1.1	3.6	-0.3	-0.3	-0.6	-0.9	0.3	0.7	1.9	1.8
Number of live births	0.2	0.3	0.9	0.4	-0.2	-0.9	0.8	0.2	0.1	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	11.8	-0.9	-2.0	0.8	-0.4	-1.8	-1.2	-2.0	-3.4
Pulse rate	1.0	1.6	3.9	-1.6	-0.8	-0.3	-1.1	0.2	1.7	2.0	1.1
Happiness	1.6	2.0	5.0	-1.6	-1.1	-2.2	-1.9	-1.6	-0.1	0.8	-0.2
Noisy workplace	1.3	1.6	6.4	0.4	2.5	0.7	0.9	1.0	-1.2	-1.0	1.2
Qualifications: A levels/AS levels or equivalent	2.0	4.4	10.5	-2.1	-0.8	-0.1	-2.5	-3.2	-2.6	-2.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.0	0.1	-0.4	-0.3	1.4	0.1	-0.0	-0.1	-1.1
Mouth/teeth dental problems: Dentures	2.7	4.5	11.6	1.4	0.8	0.3	2.0	3.0	3.4	2.7	1.4
Asthma	1.0	2.1	5.4	0.0	-2.3	-0.1	0.3	-0.1	2.3	0.8	-2.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.6	0.3	-0.4	-0.8	-0.4	-0.1	0.1	-0.1	0.1
Medication: Cholesterol lowering	0.8	1.2	4.9	-2.2	-1.3	-0.0	-0.7	-1.2	0.1	0.1	-1.0
Depression (self-reported)	0.4	0.5	1.8	0.0	0.3	0.3	0.9	1.3	0.9	0.4	-0.0
Medication: Lansoprazole	1.2	1.3	5.0	-0.6	-1.2	-0.1	0.4	0.4	1.8	2.2	-0.3
Prospective memory result	4.0	4.9	9.9	2.3	2.7	-0.7	1.4	3.1	1.0	2.0	3.2
Lung cancer (father)	0.8	0.9	2.2	1.2	1.2	0.0	1.4	1.5	0.5	0.0	0.3
Illnesses of mother	0.8	1.0	2.1	1.1	1.1	1.2	1.2	0.3	-0.8	-1.4	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	8.2	-0.7	-1.5	0.7	-0.0	-1.2	-0.7	-1.4	-2.9
Pulse wave Arterial Stiffness index	0.3	0.4	0.9	-0.9	-0.6	0.3	-0.0	-0.7	-0.6	-0.3	-1.0
Impedance of arm (left)	1.3	6.2	10.3	3.0	3.2	-1.8	2.1	3.0	0.9	1.7	3.1
Arm fat mass (right)	0.6	2.5	7.1	-1.6	-2.4	0.4	-0.5	-1.8	-0.3	-0.7	-2.7
Trunk predicted mass	0.6	3.3	7.6	-0.5	-1.5	1.7	-0.9	-2.0	-1.5	-2.5	-2.8
Standing height	0.3	2.7	6.8	2.6	2.0	0.7	0.9	0.5	-1.6	-2.5	-0.6
Length of working week for main job	0.6	0.6	2.5	-0.2	1.2	-0.1	-0.1	-0.1	-1.0	0.3	1.6
Exposure to tobacco smoke at home	0.7	0.8	2.5	0.1	0.7	1.6	-0.0	0.6	0.8	0.7	1.2
Breastfed as a baby	1.2	1.5	2.9	-0.8	0.5	1.3	-1.4	-1.4	-1.6	-1.7	0.3
Tense / ‘highly strung’	0.3	0.6	1.5	0.3	1.2	-0.7	0.8	1.2	-0.1	0.5	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	4.1	6.3	14.6	-3.6	-3.8	0.6	-2.4	-2.0	0.4	-0.8	-3.5
Hair/balding pattern: Pattern 4	0.4	1.1	3.4	-0.9	0.7	0.4	-0.3	-0.9	-1.8	-1.6	-0.3
Birth weight of first child	3.9	7.1	18.1	3.3	4.3	1.3	3.1	3.0	-0.3	-1.3	2.3
Peak expiratory flow (PEF)	0.6	1.3	6.4	0.6	-1.6	-0.2	0.5	-0.8	0.1	-0.5	-2.5
Pulse wave reflection index	0.4	0.4	1.6	0.1	-0.2	0.7	0.7	-0.1	-0.4	-0.9	-1.3
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.4	-0.3	-1.2	-0.3	-0.2	-0.5	0.1	0.5	-0.9
Loud music exposure frequency	0.1	0.1	0.2	0.4	0.3	0.4	0.3	0.2	-0.0	0.1	0.4
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.0	0.2	-0.6	0.0	-1.0	-0.5	-0.1	-0.4	0.2
Mouth/teeth dental problems: Bleeding gums	2.5	3.3	12.3	-1.5	-1.2	0.9	-3.5	-2.7	-1.5	-0.1	-0.2
Blood clot in the leg (DVT)	0.6	0.8	2.8	-0.1	-0.6	-0.1	-1.1	0.0	1.7	1.4	0.3
Medication: Paracetamol	0.5	0.8	2.7	0.8	1.3	-0.5	0.1	0.8	-0.1	0.8	1.6
Headache pain in last month	0.1	0.2	0.6	0.0	0.2	0.8	-0.6	0.2	0.2	0.5	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.2	1.1	0.5	0.4	0.5	0.5	-0.0	-0.2	-0.1
Glaucoma (self-reported)	1.7	2.0	9.3	0.0	1.5	-3.0	-0.1	-0.4	-1.3	-0.4	1.6
Gout (self-reported)	0.5	0.6	1.8	0.2	0.5	-1.3	1.0	0.0	-1.2	-0.8	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.6	0.1	-0.5	0.7	0.8	-0.4	-0.6	-0.3	-0.8
Medication: Amlodipine	0.4	0.5	1.6	-0.7	-1.2	-0.2	-0.4	-0.0	0.9	0.4	-0.9
Medication: Ventolin 100micrograms inhaler	1.9	2.4	9.1	0.6	-1.6	0.0	0.7	1.0	3.0	2.1	-1.2
Birth weight	1.3	2.8	7.3	1.7	2.7	-0.0	2.3	1.9	-0.5	-0.6	1.8
Chronic bronchitis/emphysema (mother)	1.1	1.3	4.5	-0.5	-0.3	0.2	-0.3	0.8	2.1	2.0	0.9
High blood pressure (siblings)	1.2	1.7	4.4	-1.5	-2.0	-0.2	-0.1	-1.2	-0.8	-0.8	-2.1
Forced vital capacity (FVC), Best measure	0.5	1.9	6.5	-0.5	-0.8	0.6	0.0	-1.1	-1.3	-2.1	-2.6
Body fat percentage	0.5	2.2	6.5	-1.4	-2.5	-0.5	-0.4	-1.4	0.5	0.5	-2.5
Leg fat percentage (right)	0.8	2.9	8.3	-1.9	-2.9	-0.6	-1.0	-1.9	0.3	0.5	-2.5
Arm fat-free mass (right)	1.1	5.8	14.5	-1.7	-2.8	2.2	-1.6	-2.8	-1.0	-2.3	-3.8
Exposure to tobacco smoke outside home	1.0	1.4	5.8	0.6	2.4	-0.2	0.3	1.1	-0.1	0.0	1.9
Comparative body size at age 10	0.2	0.5	2.9	0.1	0.7	-0.7	-0.3	-0.2	-0.4	0.3	1.7
Number of full brothers	1.2	1.5	5.0	-1.1	-2.2	-0.0	-0.5	-0.9	0.9	0.5	-1.9
Worry too long after embarrassment	2.6	4.3	15.6	0.8	3.6	-1.4	-0.3	1.3	-1.2	0.5	4.0
Seen a psychiatrist for nerves, anxiety, tension or depression	3.4	4.5	11.8	-3.1	-3.4	0.2	-2.0	-2.0	0.0	0.0	-2.4
Wheeze or whistling in the chest in last year	0.6	1.0	3.7	-0.0	-0.9	0.3	0.7	1.0	1.9	0.9	-1.2
Number of children fathered	0.2	0.2	0.9	0.4	-0.6	0.2	0.5	-0.0	0.2	0.2	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	5.6	-1.1	-1.2	2.4	-0.8	-1.1	-0.4	-1.7	-1.7
Age at first live birth	0.2	0.4	1.2	-0.0	-1.0	1.1	-0.1	0.2	0.5	-0.4	-1.0
Pulse wave peak to peak time	0.2	0.3	0.7	0.9	0.5	-0.2	-0.2	0.5	0.4	0.1	0.7
Health satisfaction	0.7	0.9	2.4	-0.6	-1.5	-1.1	0.2	-0.2	0.7	1.4	-0.7
Shortness of breath walking on level ground	1.5	1.8	5.3	-1.0	-2.3	-1.2	-0.8	-1.2	0.4	1.1	-1.7
Qualifications: College or University degree	0.8	2.6	7.0	-0.7	-1.2	1.3	-1.9	-2.7	-1.6	-1.9	-0.8
Eye problems/disorders: None of the above	1.0	1.2	3.8	-0.2	-0.7	2.0	-0.8	-1.0	-1.0	-1.0	-1.2
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.1	-0.3	1.0	1.1	-0.0	-0.4	-1.5	-0.9	0.2
Emphysema/chronic bronchitis	1.1	1.2	3.1	-0.3	-1.8	-0.1	0.5	0.1	1.3	1.4	-1.6
Medication for pain relief, constipation, heartburn	0.1	0.2	0.7	-0.5	0.6	0.2	0.0	-0.2	-0.9	-0.4	-0.4
Neck or shoulder pain in last month	0.2	0.3	1.4	-0.5	0.3	-1.2	0.1	0.0	-0.5	-0.5	-0.0
Medication: Blood pressure	0.2	0.3	1.1	-0.5	0.3	-0.3	-0.0	0.5	0.4	0.6	1.0
Angina (self-reported)	0.7	0.9	2.3	-1.0	-0.2	0.5	-0.3	0.6	1.4	1.5	1.1
Migraine (self-reported)	1.1	1.3	3.8	-1.0	0.5	0.1	-1.9	-1.2	-1.4	-1.1	0.9
Medication: Ibuprofen	0.2	0.3	1.3	-0.3	-0.1	-1.1	-0.8	-0.3	0.1	0.1	0.4
Medication: Allopurinol	0.5	0.7	1.6	0.7	0.9	-1.1	1.3	0.7	-0.4	-0.5	0.3
Medication: Omeprazole	0.9	1.1	3.8	-0.1	-0.9	-0.3	1.8	0.1	0.3	-0.7	-1.9
Medication: Seretide 50 evohaler	0.7	0.8	1.6	-0.9	-1.2	0.3	-1.3	-1.0	0.2	-0.5	-0.9
Mean time to correctly identify matches	0.7	1.3	3.8	-1.9	-1.4	0.6	-1.0	-0.4	1.2	1.0	-0.8
Heart disease (mother)	0.3	0.4	0.9	-0.9	-0.7	-0.5	-0.7	-0.1	0.4	0.8	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.3	0.2	-0.7	-0.5	0.3	-0.5	-0.4	-0.3	-1.1
Whole body fat mass	0.6	2.3	8.7	-1.2	-2.3	0.4	-0.3	-1.6	-0.1	-0.6	-3.0
Leg fat mass (right)	0.7	2.5	7.2	-1.5	-2.6	0.2	-0.9	-1.9	0.0	-0.2	-2.7
Arm predicted mass (right)	1.2	6.0	16.8	-1.7	-2.9	2.2	-1.2	-2.7	-1.0	-2.2	-4.1
Pulse rate, automated reading	0.4	1.3	3.1	-1.4	1.4	-1.3	-0.7	-0.2	-1.0	-0.4	1.8
Alcohol intake frequency.	0.3	0.7	1.5	-0.6	0.6	0.8	0.6	1.0	0.7	1.1	1.2
Comparative height size at age 10	0.6	3.6	14.1	3.8	2.2	0.8	1.9	2.2	0.3	-0.7	0.3
Number of full sisters	1.8	2.2	5.1	-2.1	-2.3	0.3	-1.0	-1.2	-0.1	-0.7	-2.2
Suffer from ‘nerves’	3.7	5.8	12.6	2.4	1.8	0.5	2.2	3.5	2.7	2.9	2.0
Overall health rating	1.1	2.3	7.5	0.1	-0.2	1.1	0.4	1.8	2.3	2.7	0.9
Chest pain or discomfort	0.6	0.9	2.5	-1.6	-1.3	-0.0	-0.4	-0.8	0.2	-0.2	-1.4
Had major operations	0.5	0.6	2.7	-0.7	-0.4	1.6	-0.9	-0.7	-0.2	-0.0	-0.0
Age at last live birth	0.6	0.8	2.8	0.5	-0.3	1.1	0.8	0.4	-0.3	-1.7	-1.2
Family relationship satisfaction	1.9	2.3	5.8	-1.3	-2.0	-0.6	-1.9	-2.4	-0.8	-0.5	-1.4
Leg pain on walking	0.7	0.9	2.1	-1.3	-1.5	-0.7	-0.3	-0.8	0.5	1.1	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.5	-1.6	-0.4	0.4	-1.4	-1.3	-0.7	-0.2	-0.5
Commuting to job workplace: Car/motor vehicle	2.2	2.5	8.8	-1.6	-2.0	-0.1	0.1	-1.2	-1.0	-1.6	-3.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.9	0.2	1.3	0.2	-1.4	-0.2	-0.2	-0.5	1.7
Medication: Aspirin	0.1	0.2	0.7	-0.5	-0.4	-0.5	-0.0	0.0	0.8	0.4	-0.1
Supplements: Vitamin C	0.9	1.0	2.9	0.2	-0.2	-0.8	-0.5	-1.1	-1.5	-1.7	-1.0
Knee pain experienced in last month	0.8	1.2	3.8	-0.8	-2.0	-0.1	-0.0	-0.6	1.3	1.3	-1.1
Hypertension (Self-reported)	0.3	1.0	2.9	-0.3	0.0	-0.2	-0.4	0.8	1.5	1.7	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.1	-0.5	-1.2	-0.7	0.3	0.4	1.4	1.3	-0.7
Illnesses of father: Heart disease	0.7	0.9	3.3	-1.4	-1.8	-0.3	-0.2	-0.7	0.8	0.5	-0.9
Illnesses of siblings: Diabetes	2.4	2.9	5.7	-2.3	-2.4	-0.3	-2.0	-2.2	-1.0	-0.2	-1.4
Smoking status: Previous	0.5	0.8	2.8	0.1	0.5	-1.5	0.4	-0.5	-1.7	-0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.1	1.6	1.8	0.9	0.4	0.6	-0.7	-1.2	0.6
Whole body fat-free mass	0.6	3.2	8.1	-0.6	-1.6	2.0	-0.7	-1.8	-1.1	-2.3	-2.8
Leg fat-free mass (right)	0.5	2.6	6.5	-0.5	-1.4	2.2	-0.3	-1.4	-0.9	-2.1	-2.5
Arm fat percentage (left)	0.7	2.7	7.8	-1.8	-2.8	0.1	-0.3	-1.7	0.2	-0.0	-2.7
Average weekly red wine intake	2.7	4.0	11.2	-1.2	-2.1	-0.8	-1.9	-3.4	-1.7	-2.0	-2.0
Handedness (chirality/laterality): Left-handed	0.6	0.8	1.8	0.0	1.2	0.7	-0.3	-0.1	-1.4	-1.1	1.0
Mood swings	0.2	0.4	0.9	-0.4	0.9	-0.2	-0.4	-0.1	-0.9	-0.8	0.2
Loneliness, isolation	0.2	0.3	0.9	0.4	0.7	-0.9	0.2	0.2	-0.9	0.0	0.2
Long-standing illness, disability or infirmity	0.7	1.1	3.2	0.3	-0.3	-1.4	0.6	1.1	1.8	1.5	0.1
Ever had bowel cancer screening	0.6	0.7	1.6	-0.6	-1.3	1.2	0.2	-0.4	0.4	0.1	-1.2
Diabetes diagnosed by doctor	0.9	1.5	3.0	-1.5	-1.7	-1.4	-0.3	-1.2	0.6	1.0	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.4	6.6	-0.9	-2.6	-1.0	-0.9	-0.2	2.3	2.0	-0.5
Friendships satisfaction	0.3	0.4	0.8	0.7	-0.7	0.1	0.3	-0.7	-0.5	-0.5	-0.9
Qualifications: nursing, teaching	0.7	1.1	4.2	-0.5	0.4	-0.0	-0.3	-0.9	-2.0	-1.9	-0.2
Commuting to job workplace: Walk	0.9	1.0	3.0	-0.5	0.5	-1.1	-1.6	-0.8	-0.2	0.4	1.7
Eye problems/disorders: Cataract	0.9	1.1	1.8	0.5	1.0	-0.6	0.9	1.2	1.0	1.3	1.3
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.5	0.3	-0.2	-0.8	0.6	-1.1	-2.1	-1.6	-1.5
Medication for cholesterol	0.3	0.5	1.3	0.1	0.9	0.8	0.6	0.2	-1.2	-0.9	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	1.8	1.2	-0.0	1.2	0.9	1.2	1.4	1.3	0.5
Back pain experienced in last month	0.8	1.2	5.1	0.7	0.8	-2.3	1.2	1.0	-0.2	0.6	0.7
Mineral and other dietary supplements	1.0	1.3	4.3	-0.7	-1.7	1.4	0.2	0.0	0.9	-0.1	-2.1
Breast cancer (self-reported)	0.3	0.4	0.8	-0.7	-0.8	0.9	-0.2	-0.5	-0.3	-0.1	-0.7
Asthma (self-reported)	1.1	2.2	6.9	-0.2	-2.4	-0.1	0.2	0.1	2.6	1.2	-2.0
Osteoporosis (self-reported)	1.6	2.0	4.5	2.1	1.3	-0.5	2.1	2.0	0.8	0.1	0.4
Osteoarthritis (self-reported)	0.3	0.5	1.7	0.6	-0.1	-0.0	0.3	0.5	1.0	1.3	0.6
Medication: Aspirin	0.4	0.6	2.6	-0.4	-0.5	-0.2	-0.2	0.4	1.6	1.1	0.2
Medication: Gliclazide	0.2	0.2	0.9	-0.5	-0.4	-0.2	0.3	-0.3	0.4	0.2	-1.0
Illnesses of father: None of the above (group 1)	1.7	2.0	5.4	0.4	2.3	-0.2	-0.1	-0.0	-2.1	-2.1	1.4
Smoking status: Current	0.7	1.1	3.6	-0.8	-1.2	1.7	-0.3	-0.3	0.3	-0.3	-1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	10.8	-1.5	-2.1	0.9	-0.0	-1.5	-0.7	-1.8	-3.3
Whole body water mass	0.6	3.5	8.6	-0.8	-1.8	2.0	-0.9	-2.0	-1.2	-2.4	-2.9
Leg predicted mass (right)	0.5	2.8	7.3	-0.6	-1.6	2.2	-0.3	-1.5	-0.9	-2.1	-2.7
Arm fat mass (left)	0.8	3.2	10.4	-1.6	-2.9	0.5	-0.4	-2.0	-0.1	-0.6	-3.2
Number of self-reported non-cancer illnesses	0.9	1.5	4.9	-0.0	-0.9	-0.7	1.2	1.1	2.2	1.7	-0.5
Average weekly champagne plus white wine intake	0.5	0.7	2.6	-0.2	-1.6	0.4	-0.4	-0.5	0.8	0.1	-1.2
Miserableness	0.6	1.0	3.6	-0.2	1.0	-0.5	0.1	-0.3	-1.9	-1.6	-0.6
Guilty feelings	1.4	2.0	5.7	0.7	2.4	-1.6	-0.1	0.4	-1.8	-1.4	1.4
Wears glasses or contact lenses	1.2	1.4	3.4	0.8	0.1	-0.7	1.7	1.2	1.3	1.8	0.6
Ever taken oral contraceptive pill	3.3	3.7	9.9	-1.5	-2.4	2.1	-0.9	-2.0	-0.9	-1.1	-3.1
Hearing aid user	1.5	1.7	3.6	-1.4	-1.9	0.0	-1.3	-1.9	-0.8	0.4	-1.2
Mother’s age at death	0.8	1.0	2.6	-0.3	-0.5	-1.3	-1.3	-1.6	-1.3	-0.5	-0.0
Financial situation satisfaction	0.6	0.7	2.5	-0.5	-1.6	-0.2	-0.6	-0.2	0.9	0.9	-0.9
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.7	-1.3	0.1	1.3	-0.6	-0.4	0.3	-0.5	-0.1
Commuting to job workplace: Public transport	0.7	0.9	3.6	0.7	1.1	1.9	-0.1	0.1	-0.4	-0.3	1.2
Eye problems/disorders: Glaucoma	1.7	2.0	8.3	-0.5	1.4	-2.9	-0.6	-0.2	-0.6	0.3	2.2
Medication: Blood pressure	0.7	1.2	3.8	-1.1	-1.1	-0.5	-0.8	-0.1	1.7	2.0	0.3
Pain type(s) experienced in last month: Hip pain	1.1	1.4	5.1	0.7	1.2	-2.2	0.0	0.5	-0.1	1.1	1.8
Supplements: Fish oil (including cod liver oil)	0.9	1.1	3.5	1.0	1.1	-1.4	-0.2	0.3	0.0	1.0	1.9
High cholesterol (Self-reported)	0.8	1.3	3.0	-0.7	-1.3	-1.7	-0.2	-1.4	-0.6	-0.3	-1.7
Medication: Bendroflumethiazide	0.4	0.6	1.4	-0.7	-0.1	-0.4	-1.2	-0.6	0.1	1.1	1.0
Medication: Paracetamol	0.4	0.6	1.6	-0.2	0.1	-0.6	-1.1	0.1	0.5	1.2	1.3
Medication: Lisinopril	0.5	0.6	2.1	-0.7	-0.0	-0.9	-1.5	-0.8	-0.1	0.5	1.0
Medication: Atorvastatin	0.2	0.2	0.6	-0.2	-0.1	0.3	-0.6	-0.6	-0.8	-0.5	0.0
Illnesses of father: High blood pressure	1.3	1.6	4.6	0.0	-1.6	-0.6	0.4	1.1	2.1	1.8	-0.9
Alcohol drinker status: Never	0.7	0.9	1.9	1.0	1.4	-0.8	1.3	0.9	0.0	0.2	1.0
Ever smoked	0.6	1.0	2.0	0.9	0.8	-0.9	1.3	0.2	-1.4	-1.2	-1.0
Basal metabolic rate	0.6	3.4	8.9	-0.8	-1.8	1.9	-0.8	-2.0	-1.1	-2.2	-3.0
Leg fat percentage (left)	1.0	3.6	9.6	-2.3	-3.1	-0.6	-1.1	-2.2	0.1	0.1	-2.8
Arm fat-free mass (left)	1.0	4.8	11.5	-1.7	-2.5	1.6	-1.5	-2.6	-1.2	-2.1	-3.4
Number of operations (self-reported)	1.0	1.4	3.2	-0.7	-1.7	0.2	-1.1	-0.4	1.8	1.8	-0.3
Average weekly beer plus cider intake	0.4	0.6	2.0	-1.4	-0.5	1.2	-0.9	-0.3	0.4	-0.4	-0.2
Irritability	1.5	2.6	11.7	0.1	-1.4	-0.1	0.5	-1.4	-1.0	-1.9	-3.4
Risk taking	3.6	5.3	17.8	-2.6	-4.2	1.9	-1.1	-1.8	0.6	-0.3	-3.1
Ever had prostate specific antigen (PSA) test	2.7	3.1	6.2	-1.9	-1.3	0.9	-2.4	-2.5	-1.3	-1.8	-1.4
Fractured/broken bones in last 5 years	0.8	1.0	2.4	-0.7	-0.3	1.1	1.6	1.0	1.2	1.1	-0.2
Age started oral contraceptive pill	2.3	2.8	8.3	-0.9	-0.4	-1.3	-0.7	-2.4	-2.9	-2.0	-1.1
Diastolic blood pressure, automated reading	0.4	1.2	3.2	-1.8	-1.6	-0.4	-1.1	-1.4	-0.3	0.3	-0.5
Ever depressed for a whole week	2.3	2.9	6.8	-2.6	-2.3	0.0	-1.3	-1.8	-0.3	-1.2	-2.1
Unable to work because of sickness or disability	1.3	1.7	4.8	-0.8	-1.6	1.0	0.3	0.5	2.0	2.2	-0.2
Commuting to job workplace: Cycle	3.0	3.6	6.6	-2.1	-1.6	1.0	-1.0	-2.6	-2.3	-2.0	-1.9
Myopia	0.2	0.3	0.8	0.8	0.1	0.9	-0.5	0.4	0.7	0.2	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.3	0.9	0.3	-0.1	1.0	-0.5	-1.6	-1.8	-1.0
Cholesterol lowering medication	0.8	1.2	3.3	-0.5	-1.8	-1.7	-0.6	-0.9	0.5	0.6	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	6.3	-0.4	-1.7	0.4	1.4	-0.1	0.9	-0.5	-2.5
Pain experienced in last month	0.3	0.5	2.3	0.2	0.5	1.5	-0.0	0.1	0.0	-1.3	-0.1
Supplements: Calcium	0.5	0.6	1.4	1.2	1.1	0.8	0.6	0.6	-0.3	-0.4	0.4
Basal cell carcinoma (self-reported)	0.2	0.2	0.6	-0.1	-0.2	-0.7	0.2	0.3	0.8	0.7	0.2
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.8	-1.7	-0.4	1.6	-0.3	0.0	0.4	-0.5	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.7	1.0	2.1	-0.6	-1.1	-0.4	-1.5	-0.5	1.4	1.3	0.1
Heart disease (siblings)	0.7	0.9	2.2	-0.8	-1.2	-1.5	-0.5	-0.4	0.7	1.4	-0.2
Alcohol drinker status: Previous	0.7	0.8	3.2	-1.5	-0.4	1.8	-0.7	-0.3	0.0	0.2	0.2
Pack years of smoking	0.8	1.2	3.1	-0.8	-1.0	1.8	1.2	1.1	1.2	0.5	-0.8
Impedance of whole body	1.1	5.4	8.3	2.6	2.8	-2.3	1.5	2.8	1.0	2.0	2.9
Leg fat mass (left)	0.8	3.1	8.4	-1.8	-2.7	0.2	-1.0	-2.2	-0.3	-0.6	-2.9
Arm predicted mass (left)	0.9	4.8	10.8	-1.8	-2.5	1.7	-1.5	-2.6	-1.2	-2.1	-3.3