TWAS hub - FRAT2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0510	0.0200	4.6e-04	0.036	0.020	0.031	0.021	0.037	3.0e-05	1.7e-03	9.1e-05	1.3e-03	2.3e-05
2	GTEx	Esophagus Mucosa	0.0930	0.0310	8.1e-05	0.072	NA	0.068	NA	0.090	1.5e-05	NA	2.5e-05	NA	1.4e-06
3	GTEx	Spleen	0.2290	0.0910	6.4e-03	0.016	NA	-0.011	NA	-0.006	1.2e-01	NA	8.9e-01	NA	4.8e-01
4	GTEx	Testis	0.1860	0.0580	2.9e-05	0.100	NA	0.105	NA	0.133	3.6e-05	NA	2.3e-05	NA	1.7e-06
5	GTEx	Whole Blood	0.0590	0.0270	4.3e-03	0.006	NA	0.006	NA	0.005	7.6e-02	NA	8.8e-02	NA	9.8e-02
6	METSIM	Adipose	0.0429	0.0162	1.4e-04	0.056	0.028	0.037	0.033	0.043	8.4e-09	3.9e-05	2.4e-06	9.9e-06	3.8e-07
7	NTR	Blood	0.0558	0.0128	0.0e+00	0.068	0.061	0.055	0.065	0.061	7.1e-21	5.6e-19	2.9e-17	3.1e-20	7.2e-19
8	ROSMAP	Brain Pre-frontal Cortex	0.0589	0.0176	1.9e-06	0.068	0.049	0.067	0.051	0.069	3.9e-09	5.5e-07	5.1e-09	3.4e-07	3.0e-09
9	YFS	Blood	0.1548	0.0245	0.0e+00	0.227	0.221	0.229	0.234	0.231	1.1e-72	9.2e-71	1.6e-73	4.2e-75	3.9e-74
10	TCGA	Bladder Urothelial Carcinoma	0.0460	0.0310	9.1e-03	0.009	0.017	0.009	NA	0.007	5.2e-02	1.2e-02	5.1e-02	NA	7.0e-02
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0819	0.0460	8.6e-05	0.010	0.031	0.033	NA	0.010	2.5e-02	1.9e-04	1.1e-04	NA	2.3e-02
12	TCGA	Brain Lower Grade Glioma	0.0231	0.0160	6.0e-03	-0.002	0.009	-0.002	NA	-0.002	8.1e-01	3.2e-02	8.0e-01	NA	7.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Blood White Count	29.5	218.8	357.2	17.9	16.2	6.3	17.3	17.5	12.2	13.2	17.7	13.6	7.9	12.5	18.9
Nervous feelings	6.6	12.3	21.7	4.7	3.6	1.3	4.4	4.0	2.3	2.5	4.3	2.5	2.4	3.7	4.6
Fluid intelligence score	6.6	13.8	21.6	-4.5	-4.2	-1.3	-4.5	-4.2	-2.8	-3.1	-4.5	-3.0	-1.9	-4.1	-4.7
Bipolar Disorder (2011)	6.4	6.2	10.6	-1.3	-3.1	-2.3	-1.6	-3.2	-2.9	-3.3	-1.6	-3.0	-2.1	-1.7	-2.6
Suffer from ‘nerves’	5.3	8.4	12.2	2.4	3.5	2.6	2.5	3.2	3.2	2.8	2.3	2.9	3.4	2.5	3.1
Bipolar Disorder (2018)	5.1	8.1	13.3	-2.9	-3.4	-1.3	-2.9	-3.6	-2.5	-3.4	-3.0	-2.8	-1.5	-2.7	-3.4
Prospective memory result	5.1	6.3	10.6	2.7	2.9	1.7	2.9	3.0	1.7	2.1	2.8	1.9	1.7	3.2	2.7
Birth weight of first child	5.1	9.3	17.6	4.2	3.0	0.8	4.1	3.6	2.1	2.3	4.2	2.4	0.4	2.2	4.0
Hand grip strength (left)	4.9	13.0	21.7	-4.6	-3.9	-2.7	-4.2	-3.5	-2.2	-3.0	-4.7	-2.9	-2.9	-4.0	-3.8
Average weekly red wine intake	4.8	7.1	11.4	-2.5	-3.4	-2.1	-2.6	-3.0	-2.5	-2.4	-2.7	-2.6	-2.5	-2.4	-3.0
Bipolar Disorder or Schizophrenia	4.4	10.7	16.9	-3.6	-3.7	-1.4	-3.5	-4.0	-3.0	-3.7	-3.4	-3.2	-1.6	-2.6	-4.1
Commuting to job workplace: Cycle	4.4	5.3	7.0	-2.2	-2.7	-1.8	-2.3	-2.3	-2.0	-2.2	-2.4	-2.5	-2.5	-2.3	-2.5
Seen doctor (GP) for nerves, anxiety, tension or depression	4.3	6.6	17.0	-4.1	-2.0	-0.6	-3.8	-2.8	-0.8	-1.4	-3.6	-1.8	-0.6	-2.6	-3.1
Seen a psychiatrist for nerves, anxiety, tension or depression	4.3	5.6	13.7	-3.7	-2.0	-0.6	-3.4	-2.6	-1.0	-1.0	-3.5	-1.6	-0.6	-2.1	-3.0
Risk taking	4.0	5.8	16.9	-4.1	-1.7	0.4	-3.7	-2.3	-0.5	-1.0	-3.8	-1.2	-0.2	-1.9	-3.2
Severe depression (siblings)	3.9	4.3	12.9	-3.3	-1.0	0.7	-3.0	-1.6	0.3	-0.6	-3.3	-0.5	0.2	-3.6	-2.1
Hand grip strength (right)	3.7	10.0	19.2	-4.4	-3.2	-2.0	-3.9	-3.1	-1.5	-2.2	-4.4	-2.1	-2.1	-4.0	-3.3
Illnesses of siblings: Diabetes	3.7	4.5	8.0	-2.5	-2.2	-0.8	-2.3	-2.3	-2.0	-2.0	-2.5	-2.1	-1.3	-1.8	-2.8
Ever taken oral contraceptive pill	3.7	4.2	8.8	-2.4	-2.0	-1.1	-2.5	-2.1	-1.3	-1.6	-3.0	-1.5	-0.8	-2.7	-2.1
Mouth/teeth dental problems: Dentures	3.5	5.9	9.6	1.1	2.9	2.9	1.1	2.6	3.0	2.6	1.5	2.9	3.1	1.7	2.2
Mouth/teeth dental problems: Bleeding gums	3.5	4.6	10.6	-0.7	-2.8	-1.9	-1.0	-3.0	-2.9	-2.5	-1.1	-3.2	-1.5	-0.4	-2.1
Alzheimer’s Disease (including proxy)	3.4	5.0	8.3	-2.2	-2.5	-1.2	-1.9	-2.6	-2.3	-2.5	-2.2	-2.9	-1.6	-1.3	-2.8
Verbal and Numeric Reasoning (VNR)	3.4	8.1	15.5	-3.9	-3.2	-0.3	-3.8	-3.1	-1.9	-2.1	-3.9	-1.9	-0.7	-2.5	-3.8
Ever had prostate specific antigen (PSA) test	3.4	3.9	6.7	-1.1	-2.4	-1.4	-1.0	-2.4	-2.6	-2.6	-1.0	-2.6	-2.0	-1.6	-2.0
Family relationship satisfaction	3.2	4.0	6.1	-2.1	-2.5	-0.8	-2.2	-2.4	-2.0	-2.0	-2.3	-2.2	-1.3	-0.8	-2.3
Age started oral contraceptive pill	3.2	4.0	8.3	-1.3	-2.2	-2.5	-1.1	-1.8	-2.5	-1.9	-1.3	-2.0	-2.9	-2.0	-2.0
Hearing difficulty/problems: Yes	3.1	4.8	6.8	-2.2	-2.6	-1.2	-2.1	-2.4	-2.3	-2.0	-2.2	-2.5	-2.0	-1.8	-2.5
Blood Eosinophil Count	3.0	23.4	42.9	5.9	5.4	1.7	5.6	5.8	4.1	4.1	6.0	4.4	2.4	3.3	6.5
Hearing difficulty/problems with background noise	2.9	4.7	7.4	-2.2	-2.6	-1.3	-2.3	-2.7	-2.1	-2.0	-2.2	-2.5	-1.3	-1.5	-2.4
Ever depressed for a whole week	2.9	3.6	7.4	-2.7	-1.7	-0.6	-2.5	-2.1	-1.2	-1.2	-2.5	-1.8	-1.2	-1.7	-2.4
Intelligence (Savage-Jansen 2018)	2.8	8.6	13.0	-3.5	-3.6	-1.2	-3.6	-3.2	-2.1	-2.4	-3.6	-2.2	-1.5	-3.2	-3.5
Qualifications: A levels/AS levels or equivalent	2.8	6.3	10.9	-0.9	-3.1	-3.3	-0.9	-2.6	-3.3	-2.6	-1.0	-3.2	-3.2	-0.9	-2.5
Hearing aid user	2.8	3.2	5.3	-2.2	-1.9	-0.6	-2.2	-1.9	-1.6	-1.1	-2.3	-1.5	-0.9	-1.8	-2.3
Worry (Nagel 2018)	2.7	5.6	12.5	3.1	2.3	0.3	2.8	2.8	1.5	1.4	2.5	1.6	1.4	3.5	3.0
Rheumatoid Arthritis	2.7	3.8	9.3	3.0	1.3	-0.5	2.9	1.5	0.3	1.0	3.0	0.5	-0.2	3.1	1.9
Commuting to job workplace: Car/motor vehicle	2.7	3.0	10.6	-2.4	-1.1	-0.9	-2.3	-1.3	-0.5	-1.1	-2.4	-0.9	-0.8	-3.2	-1.6
Lupus	2.6	4.0	7.2	-1.1	-2.5	-2.0	-1.4	-2.2	-2.7	-2.0	-1.5	-2.7	-2.0	-0.4	-2.1
BMI	2.6	15.2	30.4	-5.4	-3.9	-1.5	-5.5	-4.2	-1.8	-3.3	-5.5	-2.2	-1.5	-4.1	-4.3
Qualifications: CSEs or equivalent	2.6	3.4	5.1	1.9	2.0	1.5	2.0	2.2	1.7	1.1	2.0	1.6	1.3	2.3	2.1
Worry too long after embarrassment	2.6	4.4	11.7	3.3	1.2	-1.1	3.3	1.7	-0.4	0.0	3.1	0.2	-0.6	3.4	2.0
Type 2 Diabetes (T2D) (2018)	2.5	4.6	11.7	-3.1	-2.0	-0.5	-3.4	-2.4	-0.4	-1.1	-3.4	-1.2	-0.3	-2.1	-2.5
Primary Biliary Cirrhosis	2.4	3.4	8.2	-0.3	-2.2	-2.9	-0.5	-1.7	-2.5	-1.9	-0.6	-2.3	-2.6	-0.5	-1.3
Impedance of arm (right)	2.4	11.0	17.6	4.2	3.6	2.1	4.1	3.8	2.1	3.3	4.2	2.9	1.7	2.6	3.9
Diabetes (mother)	2.3	3.0	7.4	-2.7	-1.6	0.5	-2.5	-1.7	-0.5	-1.1	-2.7	-1.1	-0.1	-1.2	-2.3
Had other major operations	2.3	2.8	4.4	-1.4	-2.1	-1.1	-1.7	-2.0	-1.5	-1.8	-1.5	-1.8	-1.4	-1.3	-2.0
Shortness of breath walking on level ground	2.3	2.7	8.3	-2.7	-1.3	0.7	-2.6	-1.4	-0.5	-0.8	-2.9	-0.8	0.4	-0.9	-1.8
Lung FVC	2.2	11.4	18.8	-4.2	-3.6	-1.9	-4.3	-3.7	-1.8	-3.3	-4.3	-2.5	-1.9	-3.5	-3.8
Stomach or abdominal pain in last month	2.2	2.7	6.7	-1.7	1.5	2.6	-1.3	0.9	2.1	1.4	-1.3	2.0	2.4	-0.9	0.0
Major Depression (MDD)	2.1	2.6	9.1	-2.2	-0.5	1.6	-2.0	-1.1	0.5	-0.4	-2.1	-0.0	1.8	-3.0	-1.1
Other serious medical condition/disability diagnosed by doctor	2.1	2.7	7.2	-2.3	-1.2	-1.1	-2.3	-1.5	-0.5	-0.9	-2.4	-0.7	-0.5	-2.7	-1.5
Average weekly fortified wine intake	2.1	2.5	4.8	0.8	2.2	2.2	1.2	1.7	1.9	2.1	1.1	1.6	1.6	-0.1	1.2
Alzheimer’s Disease (in father)	2.0	2.2	4.4	-1.9	-1.2	0.4	-1.7	-1.9	-1.0	-1.3	-1.8	-1.5	0.3	-1.4	-2.1
Illnesses of siblings	2.0	2.8	9.1	3.0	0.9	-0.4	2.8	1.0	-0.3	-0.1	2.8	0.2	-0.3	1.7	1.7
Number of full sisters	2.0	2.5	6.3	-2.5	-1.1	-0.3	-2.1	-1.5	-0.6	-1.0	-2.2	-1.2	-0.6	-1.8	-2.1
Osteoporosis (self-reported)	2.0	2.4	4.7	1.2	2.2	1.1	1.4	2.2	1.7	1.0	1.3	1.9	1.2	0.8	2.0
Alzheimer’s Disease (in mother)	1.9	2.3	3.8	-1.3	-1.8	-1.4	-1.1	-1.5	-1.5	-1.7	-1.5	-1.9	-1.6	-0.8	-1.6
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	5.4	-1.4	1.1	1.9	-1.4	0.9	2.3	1.6	-0.9	1.8	2.1	0.2	0.2
Qualifications: None of the above	1.9	4.0	7.5	1.0	2.4	1.6	0.8	2.3	2.7	2.2	1.0	2.7	2.2	1.1	2.5
Schizophrenia (2018)	1.8	3.7	6.6	-2.2	-2.1	-0.7	-2.2	-2.2	-1.8	-2.1	-2.0	-1.9	-0.9	-1.2	-2.6
Triglycerides	1.8	2.9	4.4	-1.9	-1.9	-1.4	-1.8	-2.0	-1.4	-1.8	-2.1	-1.5	-0.7	-1.8	-1.7
Number of treatments/medications taken	1.8	3.3	6.6	0.5	2.0	2.1	0.3	1.8	2.5	2.3	0.7	1.9	2.6	1.5	1.6
Hayfever, allergic rhinitis or eczema	1.8	4.0	9.1	-0.6	2.0	2.9	-0.5	1.6	3.0	3.0	-0.4	2.4	2.7	-0.5	1.1
Relative age of first facial hair	1.7	3.6	9.3	-3.0	0.1	1.1	-3.1	-0.6	1.6	0.9	-2.6	1.3	1.3	-3.0	-0.7
Allergy	1.7	3.9	8.7	0.8	-1.9	-2.8	0.7	-1.2	-2.9	-2.8	0.5	-2.3	-2.9	1.0	-0.9
Happiness	1.7	2.1	3.7	-1.2	-1.9	-1.0	-1.3	-1.9	-1.6	-1.9	-1.4	-1.7	-0.5	-0.4	-1.5
Birth weight	1.7	3.7	7.3	2.7	2.0	0.2	2.7	2.3	1.2	1.0	2.7	1.4	0.2	1.7	2.4
High blood pressure (siblings)	1.7	2.4	6.8	-2.6	-1.3	-0.5	-2.5	-1.1	-0.2	-0.4	-2.4	-0.6	-0.8	-1.6	-1.8
Schizophrenia (2014)	1.6	3.6	6.6	-2.1	-2.1	-0.6	-2.1	-2.2	-1.9	-2.2	-1.9	-2.0	-1.0	-1.2	-2.6
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.6	7.5	-2.3	-2.0	-0.7	-2.3	-1.9	-1.3	-1.6	-2.0	-1.8	-1.2	-2.7	-2.1
Body mass index (BMI)	1.6	6.9	14.7	-3.7	-2.6	-0.7	-3.7	-2.8	-1.2	-2.2	-3.8	-1.6	-1.0	-2.5	-3.0
Worrier / anxious feelings	1.6	3.0	13.2	2.7	0.5	-1.5	2.3	0.7	-0.5	-0.2	2.1	-0.3	-0.6	3.6	1.4
Medication: Ventolin 100micrograms inhaler	1.6	2.1	7.5	-0.9	1.1	2.3	-0.8	0.4	1.8	1.7	-0.5	1.3	2.7	-1.1	0.2
Number of full brothers	1.6	2.0	5.9	-2.4	-0.7	1.5	-1.9	-1.0	-0.2	-0.0	-2.0	-0.5	0.4	-2.0	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.8	5.1	-2.0	-0.2	1.6	-2.3	-0.8	0.9	0.2	-1.8	0.7	1.4	0.1	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	13.0	-2.3	-1.4	-1.0	-2.1	-1.4	-0.4	-1.2	-2.3	-0.5	-1.0	-3.6	-1.8
Leg fat percentage (left)	1.6	5.8	12.1	-3.5	-2.2	-0.3	-3.4	-2.5	-1.1	-2.0	-3.5	-1.1	-0.6	-3.0	-2.7
Blood Platelet Count	1.5	17.9	35.5	2.6	4.7	4.3	1.9	4.3	6.0	5.6	1.9	4.9	5.3	-0.7	4.8
Time employed in main current job	1.5	1.7	4.5	2.1	1.3	0.2	2.0	1.3	0.4	0.8	1.9	0.5	0.2	1.4	1.5
Noisy workplace	1.5	1.8	4.5	2.1	1.0	-1.3	1.8	1.1	0.6	0.7	1.9	0.4	-0.3	1.3	2.0
Impedance of arm (left)	1.5	6.7	10.2	3.2	2.9	1.8	3.2	3.1	1.8	2.6	3.2	2.3	1.4	1.4	3.0
Exposure to tobacco smoke outside home	1.5	2.0	4.8	2.2	0.9	-0.3	1.8	1.0	0.4	0.7	2.2	0.2	0.2	2.2	1.9
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	7.7	-2.0	0.1	0.9	-1.8	0.0	1.3	0.3	-1.8	0.6	0.5	-2.8	-0.8
Neuroticism (Nagel 2018)	1.4	3.4	7.5	2.7	1.3	-1.2	2.5	2.2	0.3	0.1	2.1	0.8	-0.1	2.7	2.6
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.2	-1.5	-1.4	-0.8	-1.6	-1.8	-0.7	-0.7	-1.4	-1.3	-0.2	-1.4	-1.4
Medication: Metformin	1.4	2.0	4.4	-1.9	-1.6	-0.5	-2.1	-1.7	-0.3	-0.8	-2.1	-0.9	-0.3	-1.2	-1.6
Medication: Atenolol	1.4	1.7	4.6	1.9	1.1	0.5	1.9	1.1	0.3	1.0	2.1	-0.2	-0.1	1.9	1.2
Alcohol usually taken with meals	1.4	2.3	3.9	-1.5	-2.0	-0.9	-1.5	-1.7	-1.4	-1.3	-1.9	-1.2	-0.6	-1.6	-1.9
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	4.5	-2.1	-1.2	-0.3	-2.1	-1.4	-0.6	-0.6	-1.9	-0.8	-0.4	-0.3	-1.5
Financial difficulties in last 2 years	1.4	1.9	6.3	-2.3	-0.7	1.1	-2.5	-1.0	0.3	0.2	-2.3	-0.0	0.7	-0.3	-1.4
Lung cancer (father)	1.4	1.6	2.8	1.2	1.5	0.8	1.3	1.6	0.9	1.4	1.3	1.4	1.0	0.6	1.7
Emphysema/chronic bronchitis	1.4	1.6	4.2	-2.0	-0.1	1.4	-2.0	-0.4	1.0	0.4	-1.8	0.9	1.3	-1.1	-0.7
Migraine (self-reported)	1.4	1.7	4.0	0.3	-1.1	-1.8	0.6	-1.0	-2.0	-1.8	0.5	-1.8	-1.7	0.8	-0.8
Fasting Glucose	1.3	1.6	4.0	-2.0	-0.7	1.4	-1.5	-1.1	-0.1	-0.2	-1.5	-0.5	0.8	-1.8	-1.6
Neuroticism	1.3	3.1	9.6	2.7	1.1	-0.9	2.3	1.7	-0.0	0.1	2.1	0.6	0.3	3.1	2.2
Breastfed as a baby	1.3	1.6	5.1	0.2	-1.2	-1.7	0.2	-1.1	-1.7	-1.6	0.3	-1.6	-2.2	-0.1	-1.0
Leg fat percentage (right)	1.3	4.7	10.5	-3.2	-1.9	-0.1	-3.2	-2.3	-0.9	-1.7	-3.2	-0.9	-0.2	-2.7	-2.4
Illnesses of father: None of the above (group 1)	1.3	1.7	4.5	1.5	-0.0	-2.1	1.8	0.4	-1.1	-0.4	1.6	-0.4	-1.9	1.2	0.8
Mother’s age at death	1.3	1.7	3.4	-0.4	-1.6	-1.7	-0.5	-1.6	-1.7	-1.8	-0.4	-1.3	-1.3	-0.8	-1.2
Allergy or Eczema	1.2	3.2	8.3	-0.0	2.1	2.6	0.1	1.7	2.6	2.9	0.4	2.1	2.0	-0.1	1.2
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	4.6	-1.6	-1.5	-0.7	-1.9	-1.4	-0.9	-1.8	-2.1	-1.2	-0.2	-0.4	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	3.9	-1.1	-0.9	-0.9	-1.0	-1.2	-1.0	-0.8	-0.9	-1.1	-1.2	-2.0	-1.5
Illnesses of father: High blood pressure	1.2	1.5	5.2	-0.9	1.0	1.9	-0.7	0.5	1.5	0.9	-0.9	1.5	2.3	-0.2	-0.0
Irritability	1.2	2.1	5.3	-2.0	-1.4	-1.0	-2.3	-1.2	-0.4	-0.7	-2.2	-0.6	-0.6	-2.1	-0.9
Leg fat mass (left)	1.2	4.7	9.6	-2.9	-2.1	-0.7	-2.9	-2.4	-1.1	-2.1	-3.1	-1.1	-0.7	-2.5	-2.2
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.4	-1.9	-0.5	0.9	-2.0	-0.5	0.6	-0.0	-2.1	0.5	1.1	-0.8	-0.8
Serious illness, injury or assault to yourself	1.1	1.3	3.2	-1.5	0.2	1.8	-1.5	-0.2	1.0	0.6	-1.3	0.6	1.1	-1.6	-0.5
Waist circumference	1.1	4.1	8.3	-2.6	-2.2	-1.2	-2.7	-2.1	-1.1	-2.0	-2.9	-1.1	-1.1	-2.1	-2.0
Neuroticism score	1.1	2.2	7.8	2.3	0.5	-1.4	2.0	0.8	-0.5	-0.5	1.8	-0.1	0.0	2.8	1.7
Qualifications: College or University degree	1.1	3.5	8.0	-0.7	-2.4	-1.8	-0.6	-2.1	-2.8	-1.8	-0.9	-2.4	-2.3	-0.8	-2.2
Arm fat percentage (left)	1.1	4.3	10.5	-3.2	-1.6	0.2	-3.1	-1.8	-0.4	-1.1	-3.2	-0.6	-0.4	-2.9	-2.3
Diabetes diagnosed by doctor	1.1	1.8	5.2	-2.1	-1.2	-0.2	-2.2	-1.3	-0.0	-0.9	-2.3	-0.6	0.2	-0.9	-1.4
Eye problems/disorders: Cataract	1.1	1.2	3.0	0.9	1.2	0.7	1.0	1.3	0.9	0.4	0.9	1.5	1.1	1.7	1.1
Arm fat mass (left)	1.1	4.5	11.1	-3.2	-1.9	-0.3	-3.1	-2.0	-0.6	-1.6	-3.3	-0.7	-0.5	-2.8	-2.2
Number of self-reported non-cancer illnesses	1.1	2.0	5.6	-1.1	1.1	2.0	-1.0	1.0	2.4	1.7	-0.9	1.4	1.9	-0.2	0.4
Guilty feelings	1.1	1.6	3.2	1.6	0.3	-1.7	1.8	0.6	-0.8	-1.0	1.5	-0.2	-1.3	1.8	1.1
Impedance of whole body	1.1	5.5	8.5	2.8	2.6	1.7	2.9	2.6	1.5	2.3	2.9	2.1	1.5	1.3	2.7
LDL Cholesterol	1.0	1.7	3.4	-0.6	-1.4	-1.2	-0.7	-1.6	-1.8	-1.7	-0.9	-1.6	-1.0	-0.7	-1.3
Sensitivity / hurt feelings	1.0	1.7	6.3	1.8	-0.8	-2.5	1.3	0.2	-1.3	-0.9	1.1	-0.6	-1.2	1.3	1.1
Pack years adult smoking proportion	1.0	1.5	6.0	-0.7	1.4	2.5	-0.3	1.1	1.6	1.5	-0.4	1.0	1.3	-0.9	0.2
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	5.2	-1.4	-1.6	-0.5	-1.4	-1.6	-1.3	-1.4	-1.1	-1.8	-1.3	-2.3	-1.6
Arm fat-free mass (right)	1.0	5.0	8.4	-2.6	-2.5	-1.6	-2.5	-2.7	-1.5	-2.9	-2.7	-1.5	-1.0	-2.1	-2.1
Leg fat mass (right)	1.0	3.8	8.7	-2.8	-1.8	-0.4	-2.8	-2.1	-0.9	-1.8	-2.9	-0.8	-0.3	-2.3	-2.0
Arm predicted mass (right)	1.0	5.0	8.6	-2.7	-2.5	-1.5	-2.7	-2.6	-1.3	-2.7	-2.9	-1.3	-0.8	-2.3	-2.0
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.3	-0.5	-1.4	-1.0	-0.8	-1.4	-1.3	-1.5	-0.8	-1.5	-0.9	-0.4	-0.9
Wears glasses or contact lenses	1.0	1.1	2.9	-0.1	1.2	1.5	0.1	1.4	1.2	1.7	-0.1	1.0	1.3	0.4	0.6
Unable to work because of sickness or disability	1.0	1.3	3.6	-1.0	0.5	1.9	-1.2	0.1	1.8	0.7	-1.0	0.8	1.8	-0.8	-0.1
Body Mass Index (BMI) (2010)	0.9	1.2	4.4	-0.4	0.9	1.4	-0.4	0.8	1.6	1.0	-0.4	0.7	1.4	-2.1	0.5
HbA1C	0.9	1.1	3.2	-1.0	-1.0	0.0	-1.8	-1.2	-0.1	-0.1	-1.6	-0.5	-0.3	-1.3	-1.3
Neuroticism (2016)	0.9	1.3	4.3	1.7	0.7	-0.6	1.6	1.2	-0.0	-0.2	1.4	0.2	0.3	2.1	1.3
Respiratory disease	0.9	2.1	4.5	-1.6	0.5	2.1	-1.6	-0.4	1.6	1.2	-1.2	1.0	2.0	-2.1	-0.3
Maternal smoking around birth	0.9	1.3	2.5	-1.4	-1.0	0.1	-1.0	-1.3	-1.2	-1.1	-1.2	-1.2	-0.6	-1.0	-1.6
Multivitamins +/- minerals	0.9	1.1	3.1	1.6	1.3	0.4	1.8	1.2	0.1	0.4	1.7	0.2	-0.2	0.4	1.0
Supplements: Glucosamine	0.9	1.1	2.0	-0.8	-1.2	-1.3	-0.8	-0.9	-1.2	-1.4	-1.0	-1.3	-0.9	0.7	-0.9
Pain all over the body in last month	0.9	0.9	2.7	0.6	1.0	0.9	0.5	0.9	1.0	1.0	0.3	0.5	1.3	1.6	1.0
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	8.7	-1.8	-1.7	-1.7	-1.7	-1.7	-0.8	-1.9	-2.0	-0.6	-0.7	-3.0	-1.3
Asthma	0.9	1.8	3.9	-1.7	0.3	1.8	-1.6	-0.5	1.2	1.0	-1.4	0.6	1.7	-2.0	-0.7
Medication: Lansoprazole	0.9	1.0	3.1	-1.2	0.2	1.1	-1.4	0.0	0.9	0.7	-1.2	1.0	1.8	0.6	-0.1
Body fat percentage	0.9	3.5	8.5	-2.9	-1.4	0.4	-2.8	-1.6	-0.4	-1.0	-2.9	-0.4	-0.0	-2.6	-1.9
Medication: Omeprazole	0.9	1.1	5.6	-1.4	0.3	0.5	-1.2	0.5	1.3	0.3	-1.1	0.7	0.3	-2.4	-0.2
Overall health rating	0.9	2.0	6.4	0.5	1.6	2.2	0.4	1.1	1.8	1.3	0.4	1.3	2.5	0.8	1.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.3	1.5	0.1	-1.1	1.5	-0.1	-1.1	-0.6	1.5	-0.6	-1.1	1.3	0.1
Supplements: Vitamin C	0.9	1.0	2.0	-0.3	-1.0	-1.4	-0.3	-1.0	-1.4	-1.2	-0.4	-1.3	-1.2	-0.9	-0.7
Commuting to job workplace: Walk	0.9	0.9	2.9	0.6	-0.9	-1.0	0.6	-0.9	-1.3	-1.1	0.6	-1.0	-0.8	1.7	-0.5
Mineral and other dietary supplements	0.9	1.2	6.2	-1.1	0.0	1.0	-1.2	-0.6	1.0	0.7	-1.1	0.6	0.9	-2.5	-0.4
Asthma (self-reported)	0.9	1.9	4.5	-1.8	0.4	2.1	-1.6	-0.4	1.3	1.0	-1.4	0.7	1.9	-1.6	-0.7
High cholesterol (Self-reported)	0.9	1.6	3.9	-1.7	-1.4	-0.6	-2.0	-1.2	-0.1	-0.4	-1.9	-0.9	-0.4	-1.6	-1.1
Arm fat-free mass (left)	0.9	4.5	7.7	-2.4	-2.4	-1.7	-2.4	-2.6	-1.6	-2.8	-2.7	-1.4	-1.1	-1.6	-2.1
Cholesterol lowering medication	0.9	1.3	3.9	-1.8	-0.9	0.1	-2.0	-1.1	0.2	0.1	-1.8	-0.4	0.3	-1.1	-1.3
Schizophrenia vs Biploar Disorder	0.8	1.1	6.6	0.8	1.0	0.5	0.8	1.1	0.6	0.7	0.8	0.7	0.8	2.6	0.6
Medication: Co-codamol	0.8	1.0	2.9	-1.5	-0.6	0.1	-1.6	-0.5	0.3	-0.5	-1.4	-0.3	-0.4	-1.7	-0.8
Taking other prescription medications	0.8	1.2	3.4	-0.8	0.8	1.6	-1.0	0.7	1.9	1.1	-0.5	1.1	1.6	-0.4	0.4
Chronic bronchitis/emphysema (father)	0.8	1.0	2.5	-1.3	0.3	1.6	-1.2	-0.0	0.8	0.4	-1.3	0.3	1.0	-1.5	-0.5
Weight	0.8	3.8	7.0	-2.4	-2.1	-1.2	-2.4	-2.2	-1.2	-2.3	-2.6	-1.0	-1.0	-2.1	-1.8
Medication: Cholesterol lowering	0.8	1.2	2.3	-1.2	-1.3	-0.3	-1.5	-1.3	-0.5	-0.7	-1.4	-1.4	-0.3	-1.1	-1.2
Arm fat mass (right)	0.8	3.5	8.2	-2.7	-1.7	-0.4	-2.7	-1.9	-0.8	-1.6	-2.9	-0.7	-0.7	-2.2	-2.0
Wheeze or whistling in the chest in last year	0.8	1.4	4.2	-0.5	1.0	2.1	-0.6	0.4	1.5	1.7	-0.4	0.8	1.9	-0.6	0.5
Eye problems/disorders: None of the above	0.8	0.9	1.8	-0.7	-1.1	-0.7	-0.8	-1.0	-1.1	-0.5	-0.8	-1.3	-0.8	-1.2	-0.8
Whole body fat mass	0.8	3.2	7.5	-2.6	-1.5	-0.1	-2.5	-1.7	-0.6	-1.4	-2.7	-0.5	-0.3	-2.7	-1.7
Comparative height size at age 10	0.8	4.4	8.4	2.7	2.2	1.0	2.8	2.4	1.6	1.6	2.4	2.4	1.2	0.5	2.9
Illnesses of father: Heart disease	0.8	1.1	3.3	-1.5	-0.7	1.0	-1.8	-0.8	0.1	-0.1	-1.5	-0.8	0.1	-0.9	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.9	0.5	1.4	1.2	0.7	1.1	0.9	0.9	0.5	1.1	1.4	-0.5	0.7
Arm predicted mass (left)	0.8	4.3	7.4	-2.3	-2.4	-1.6	-2.3	-2.5	-1.6	-2.7	-2.5	-1.4	-1.1	-1.6	-2.0
Breast Cancer	0.7	1.7	9.0	1.0	0.8	1.2	0.9	1.4	0.7	0.8	0.9	1.2	0.9	3.0	1.0
Ulcerative Colitis	0.7	1.0	2.1	1.2	1.3	0.9	1.1	1.2	0.6	0.9	1.4	1.1	0.8	0.2	0.8
Vitamin and mineral supplements	0.7	1.0	2.1	-1.3	-1.3	-0.5	-1.5	-1.2	-0.5	-0.8	-1.4	-0.6	-0.1	-0.5	-1.2
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.7	1.1	0.9	0.5	1.0	0.8	0.5	0.2	0.8	0.9	1.2	1.6	0.9
Forced vital capacity (FVC)	0.7	2.8	7.0	-1.4	-1.8	-2.3	-1.4	-1.8	-1.1	-2.1	-1.5	-0.9	-1.3	-2.6	-1.1
Medication: Simvastatin	0.7	1.0	3.2	-1.4	-0.9	0.0	-1.8	-0.9	0.3	-0.3	-1.5	-0.7	0.4	-1.1	-1.0
Arm fat percentage (right)	0.7	2.9	7.4	-2.7	-1.3	0.2	-2.6	-1.5	-0.4	-0.9	-2.7	-0.4	-0.5	-2.2	-1.9
Medication: Seretide 50 evohaler	0.7	0.8	2.1	-1.1	-1.0	-0.1	-1.2	-1.4	-0.6	-0.5	-0.9	-1.0	-0.3	-0.5	-1.1
Chest pain or discomfort	0.7	1.0	3.0	-1.3	-0.9	-0.0	-1.4	-1.1	-0.2	-0.7	-1.3	-0.6	-0.2	-1.7	-1.0
Leg pain on walking	0.7	0.9	3.0	-1.5	-0.8	0.2	-1.7	-0.9	0.1	-0.3	-1.7	-0.4	0.5	-0.4	-0.9
Knee pain experienced in last month	0.7	1.1	3.4	-1.6	-0.6	0.7	-1.8	-0.8	0.4	-0.3	-1.6	-0.0	1.0	-1.2	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.2	-1.2	0.3	1.5	-1.2	0.3	1.2	0.3	-1.1	0.4	1.4	0.3	-0.2
Ever had bowel cancer screening	0.7	0.9	2.7	-1.6	-0.4	0.9	-1.4	-0.3	0.2	-0.3	-1.5	0.1	-0.1	-1.1	-0.9
Financial situation satisfaction	0.7	0.9	3.0	-1.7	-0.3	0.7	-1.5	-0.8	0.3	-0.0	-1.6	-0.2	0.7	-0.7	-0.9
Pack years of smoking	0.7	1.0	4.2	-0.8	1.1	2.0	-0.4	0.8	1.3	1.2	-0.6	0.6	1.0	-0.9	-0.0
Crohns Disease (2017)	0.6	1.3	2.9	0.3	-1.0	-1.7	0.4	-1.1	-1.5	-1.5	0.5	-1.6	-1.7	-0.1	-0.7
Ovarian Cancer	0.6	0.8	2.7	-0.4	-0.9	-0.8	-0.2	-0.6	-1.3	-1.6	-0.4	-1.0	-1.3	-0.1	-1.0
Coronary Artery Disease (CAD)	0.6	0.7	1.8	-1.3	-0.0	1.0	-1.0	-0.7	0.2	-0.2	-0.9	-1.0	0.2	-1.0	-0.9
Medication for hormone replacement therapy	0.6	0.7	1.8	-1.2	-0.8	-0.3	-1.1	-0.8	-0.2	-0.5	-1.3	-0.3	-0.3	-0.8	-0.9
Trunk fat percentage	0.6	2.2	5.8	-2.4	-0.9	0.8	-2.2	-1.1	-0.1	-0.7	-2.4	-0.0	0.3	-2.3	-1.4
Trunk fat mass	0.6	2.6	6.4	-2.5	-1.3	0.2	-2.3	-1.5	-0.3	-1.3	-2.5	-0.2	0.0	-2.5	-1.5
Had menopause	0.6	0.8	2.1	-1.2	-0.2	1.2	-1.4	-0.5	0.7	0.7	-1.2	0.4	0.9	-0.0	-0.7
Depression (self-reported)	0.6	0.7	1.9	-0.1	1.3	0.7	0.1	0.9	1.4	1.1	0.2	0.7	0.9	0.6	0.8
Length of working week for main job	0.6	0.7	3.2	1.3	-0.2	-0.5	0.9	0.0	-0.7	-0.2	0.7	-0.7	-0.4	1.8	0.5
Glaucoma (self-reported)	0.6	0.7	2.1	0.9	-0.4	-1.0	0.7	0.2	-0.6	-0.8	0.9	-0.5	-1.2	1.4	0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.4	-0.3	0.6	1.5	-0.4	0.4	1.0	0.4	-0.1	1.1	1.4	1.2	0.2
Health satisfaction	0.6	0.8	2.5	-1.3	-0.2	1.2	-1.2	-0.3	0.4	-0.3	-1.6	-0.1	0.9	-1.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.6	1.9	0.5	-0.6	1.7	0.7	-0.1	-0.2	1.7	0.5	-0.2	1.2	1.5
Handedness (chirality/laterality): Left-handed	0.6	0.8	1.6	0.9	-0.2	-1.3	0.9	-0.1	-0.9	-1.0	1.1	-0.4	-1.2	1.0	0.3
Long-standing illness, disability or infirmity	0.6	0.9	2.4	-0.4	1.0	0.8	-0.3	0.8	1.4	1.2	-0.2	1.3	1.6	0.4	0.5
Qualifications: nursing, teaching	0.6	0.9	3.5	0.0	-1.0	-1.4	0.2	-0.6	-1.5	-0.2	0.0	-1.3	-1.9	-0.4	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.9	-0.9	-1.3	-2.0	-1.1	-0.6	-0.6	-0.5	-1.2	-0.3	-1.1	-0.2	-0.4
Alcohol drinker status: Never	0.6	0.8	1.8	1.1	0.8	0.3	0.9	1.3	0.7	0.8	1.0	0.8	0.2	0.8	1.1
Number of operations (self-reported)	0.6	0.8	1.8	-1.1	-0.4	1.3	-1.3	-0.9	0.4	-0.4	-1.1	-0.0	1.1	-0.8	-1.0
Fractured/broken bones in last 5 years	0.6	0.7	1.7	0.0	0.9	1.0	-0.1	1.0	1.3	1.1	-0.1	0.7	1.3	-0.3	0.7
Diastolic blood pressure, automated reading	0.6	2.0	3.9	-2.0	-1.5	-0.7	-1.9	-1.5	-1.0	-1.0	-2.0	-1.2	-0.7	-0.4	-1.8
Heart disease (siblings)	0.6	0.7	2.2	-1.4	-0.6	0.4	-1.5	-0.6	0.1	0.1	-1.4	-0.3	0.4	-0.6	-1.0
Prostate Cancer	0.5	0.7	1.4	0.8	1.1	0.3	1.0	0.9	0.7	1.0	1.2	1.0	0.6	0.2	0.9
Mean Putamen Volume	0.5	0.5	1.0	-0.3	-0.8	-0.7	-0.2	-0.5	-0.9	-1.0	-0.4	-1.0	-0.9	1.0	-0.6
Impedance of leg (right)	0.5	2.6	5.1	2.2	1.7	1.0	2.2	1.6	0.7	1.2	2.3	1.3	1.2	0.8	1.9
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.3	-1.0	-0.0	0.3	-1.1	0.3	1.1	0.6	-0.9	0.6	0.2	-1.0	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	5.4	-1.3	-1.2	-1.2	-1.4	-1.2	-0.3	-1.7	-1.5	0.0	-0.2	-2.3	-0.7
Tense / ‘highly strung’	0.5	0.8	1.9	0.5	1.0	-0.0	0.5	0.9	1.2	0.7	0.6	1.1	0.7	1.1	1.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.0	-1.2	-0.6	0.7	-1.3	-0.5	0.2	-0.6	-1.4	-0.5	0.3	-0.2	-0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.4	0.7	-0.5	-1.6	0.5	-0.1	-0.9	-0.3	0.5	-1.2	-1.1	0.1	0.2
Back pain experienced in last month	0.5	0.7	1.8	0.8	1.0	-0.0	0.6	1.1	1.1	0.5	0.5	1.3	0.7	0.2	1.2
Smoking status: Current	0.5	0.7	2.5	-1.2	-0.3	0.5	-1.3	-0.8	0.3	-0.0	-1.2	-0.5	0.4	-1.6	-0.4
Average weekly champagne plus white wine intake	0.5	0.7	1.7	-1.2	-0.5	1.0	-1.3	-0.8	-0.0	0.0	-1.3	0.3	0.3	-0.8	-1.0
Miserableness	0.5	0.8	4.2	0.9	-0.3	-2.0	0.9	-0.0	-0.7	-1.3	0.6	-0.6	-0.8	-0.2	0.6
Eye problems/disorders: Glaucoma	0.5	0.6	2.7	1.0	-0.3	-0.6	0.9	0.2	-0.5	-0.6	1.1	-0.5	-0.8	1.6	0.2
Reaction Time	0.4	0.8	2.0	-0.8	-0.8	-0.1	-0.6	-1.1	-1.2	-0.8	-0.6	-1.3	-0.2	-0.5	-1.4
Age at First Birth	0.4	0.6	1.4	-1.1	0.4	0.9	-1.0	0.1	0.8	0.5	-1.2	1.0	1.0	-0.3	-0.3
Crohns Disease (2012)	0.4	0.6	1.5	-0.0	-0.9	-0.7	-0.2	-1.1	-0.8	-0.9	0.1	-1.2	-1.1	-0.6	-0.7
HDL Cholesterol	0.4	0.6	2.5	1.0	0.5	0.6	1.1	0.5	-0.2	0.1	1.1	-0.4	-0.1	1.6	0.4
Chronotype (morning person)	0.4	1.0	3.1	1.8	0.6	-0.4	1.4	0.9	0.3	0.4	1.5	0.6	-0.2	0.0	1.5
Ever had hysterectomy (womb removed)	0.4	0.5	1.4	-1.1	-0.0	0.8	-1.2	-0.4	0.9	0.4	-0.7	0.5	0.7	0.2	-0.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.2	1.1	0.7	0.2	1.0	0.3	0.5	0.4	0.8	0.3	0.7	0.9	0.7
Current tobacco smoking	0.4	0.6	2.0	-1.1	0.1	0.9	-1.0	-0.6	0.6	0.2	-1.0	-0.2	0.9	-1.4	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.3	1.0	0.7	0.8	1.2	0.7	0.4	-0.3	1.0	0.3	0.5	0.8	0.7
Age when periods started (menarche)	0.4	0.9	2.6	-0.9	-1.1	-0.5	-0.8	-1.3	-1.0	-1.6	-0.8	-1.0	-0.5	-0.0	-1.0
Past tobacco smoking	0.4	0.8	2.8	0.8	0.9	1.7	1.0	0.5	0.4	0.8	1.1	0.4	1.1	0.9	0.2
Hair/balding pattern: Pattern 2	0.4	0.5	1.8	-0.8	-0.5	-0.4	-0.6	-0.5	-0.3	-0.4	-0.6	-0.4	-0.9	-1.3	-0.7
Diabetes (self-reported)	0.4	0.7	2.1	-1.3	-0.4	0.3	-1.4	-0.5	0.5	-0.2	-1.5	0.0	0.7	-0.8	-0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.5	-0.4	1.0	0.7	-0.1	0.8	1.2	1.2	-0.2	1.1	0.4	-0.4	0.3
Trunk fat-free mass	0.4	2.4	6.5	-1.1	-1.9	-1.7	-1.3	-1.9	-1.4	-2.5	-1.5	-1.0	-1.1	-1.1	-1.1
Pulse wave Arterial Stiffness index	0.4	0.5	1.1	-0.7	-0.8	-1.0	-0.5	-0.6	-0.4	-0.9	-0.8	-0.7	-0.1	-0.7	-0.5
Trunk predicted mass	0.4	2.3	6.4	-1.1	-1.9	-1.7	-1.3	-1.8	-1.4	-2.5	-1.5	-1.0	-1.1	-1.1	-1.1
Hair/balding pattern: Pattern 4	0.4	0.9	2.9	0.2	-1.1	-1.7	-0.0	-0.6	-0.9	-1.0	0.0	-1.4	-1.6	-0.2	-0.2
Peak expiratory flow (PEF)	0.4	0.9	5.2	-1.0	-0.7	-0.1	-1.1	-0.5	0.2	-0.6	-1.3	0.4	0.5	-2.3	-0.5
Medication: Paracetamol	0.4	0.7	1.9	1.2	0.7	0.2	1.1	0.8	-0.0	0.1	1.2	0.3	0.4	1.4	1.0
Friendships satisfaction	0.4	0.5	1.4	-1.0	-0.8	0.1	-1.0	-0.5	-0.4	-0.9	-1.2	-0.3	-0.5	-0.2	-0.7
Breast cancer (self-reported)	0.4	0.4	2.1	-0.5	-0.4	-0.0	-0.8	-0.8	-0.2	-0.3	-0.5	-0.5	-0.4	-1.4	-0.7
Whole body water mass	0.4	2.3	5.3	-1.5	-1.8	-1.4	-1.5	-1.8	-1.2	-2.3	-1.8	-0.9	-0.9	-1.2	-1.2
Commuting to job workplace: Public transport	0.4	0.5	1.8	1.2	0.3	-0.3	1.3	0.4	-0.6	-0.1	1.3	-0.1	-0.6	0.4	0.3
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.5	0.9	0.4	-0.2	1.0	0.6	0.1	-0.4	0.8	0.4	0.3	1.6	0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.6	2.9	0.9	0.4	-0.3	1.1	0.7	-0.5	-0.2	0.8	-0.1	-0.1	1.7	0.4
Medication: Lisinopril	0.4	0.5	1.2	0.1	-0.9	-0.9	-0.1	-0.9	-1.1	-0.8	0.1	-1.1	-0.5	0.7	-0.6
Basal metabolic rate	0.4	2.4	4.9	-1.7	-1.8	-1.3	-1.7	-1.8	-1.1	-2.2	-2.0	-0.8	-0.9	-1.3	-1.3
Supplements: Calcium	0.4	0.4	1.2	0.7	0.7	-0.3	0.9	0.9	-0.1	0.3	0.8	0.4	-0.0	1.1	0.8
Irritable Bowel Disease (IBD)	0.3	0.8	2.0	0.5	-0.4	-1.4	0.6	-0.7	-1.2	-1.0	0.9	-0.9	-1.2	-0.1	-0.6
Hypothyroidism (self reported)	0.3	0.6	1.6	-1.0	-0.9	-0.4	-1.3	-0.6	-0.2	-0.8	-1.3	-0.4	-0.5	-0.3	-0.9
Average weekly spirits intake	0.3	0.3	1.0	-0.1	-0.6	-0.3	-0.3	-0.6	-0.8	-1.0	-0.3	-0.6	-0.5	-0.4	-0.6
Diabetes (father)	0.3	0.4	1.3	-1.0	-0.6	0.4	-1.1	-0.5	0.0	-0.3	-0.9	-0.3	0.4	0.2	-0.6
Impedance of leg (left)	0.3	1.5	3.7	1.8	1.3	0.6	1.8	1.1	0.3	0.8	1.9	0.9	0.7	0.5	1.4
Medication: Ramipril	0.3	0.4	0.9	-0.9	0.2	0.6	-0.7	0.3	0.9	0.1	-0.9	0.1	0.7	-0.8	-0.1
Hip circumference	0.3	1.3	2.4	-1.2	-1.3	-1.0	-1.1	-1.3	-1.1	-1.5	-1.4	-0.7	-0.9	-0.8	-1.0
Falls in the last year	0.3	0.4	2.0	-0.0	0.8	0.7	-0.2	0.4	0.8	0.6	0.0	0.8	1.4	-0.0	0.4
Pulse rate	0.3	0.5	2.4	-0.5	0.3	1.0	-0.3	-0.1	0.3	0.4	-0.4	-0.2	1.0	1.6	-0.6
Exposure to tobacco smoke at home	0.3	0.4	0.8	0.7	0.6	0.8	0.5	0.5	0.6	0.4	0.9	0.2	0.4	0.7	0.6
Medication: Amlodipine	0.3	0.4	1.0	-1.0	0.1	0.5	-0.9	-0.3	0.5	0.0	-0.8	0.3	0.7	-0.5	-0.6
Forced vital capacity (FVC), Best measure	0.3	1.2	3.9	-0.7	-1.1	-1.8	-1.0	-1.1	-0.3	-1.6	-1.0	0.0	-0.6	-2.0	-0.3
Number of children fathered	0.3	0.3	2.5	-0.7	-0.2	-0.0	-0.6	-0.1	0.1	0.4	-0.6	0.1	0.5	-1.6	0.0
Angina (self-reported)	0.3	0.4	1.8	0.5	0.5	1.3	0.4	0.4	0.3	0.7	0.7	-0.2	0.8	0.6	0.1
Mean time to correctly identify matches	0.3	0.5	1.2	-1.1	-0.3	0.7	-0.9	-0.6	-0.2	-0.1	-0.9	-0.5	0.5	-0.9	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.3	-0.5	-0.6	-0.4	-0.6	-0.4	-0.4	-0.1	-0.7	0.1	0.0	-1.5	-0.3
Alcohol intake frequency.	0.3	0.6	1.0	0.9	1.0	0.8	0.9	1.0	0.8	0.1	0.8	0.4	0.9	0.8	0.9
Had major operations	0.3	0.3	1.1	-0.1	-0.6	-0.3	-0.2	-0.8	-0.7	-1.1	-0.3	-0.8	-0.3	-0.7	-0.5
Smoking status: Previous	0.3	0.4	2.4	-0.3	-0.6	-1.6	-0.5	-0.2	-0.3	-0.8	-0.6	-0.1	-0.9	-0.3	-0.1
Whole body fat-free mass	0.3	1.9	4.6	-1.4	-1.6	-1.3	-1.4	-1.7	-1.0	-2.1	-1.7	-0.7	-0.8	-1.1	-1.1
Medication: Aspirin	0.3	0.3	1.3	0.0	0.3	1.1	0.0	0.0	0.9	0.9	0.2	0.2	1.0	-0.1	0.2
Medication: Gliclazide	0.3	0.3	2.5	-0.5	-0.4	-0.1	-0.7	-0.4	0.3	-0.1	-0.5	0.1	0.2	-1.6	-0.1
Leg predicted mass (right)	0.3	1.4	3.1	-1.5	-1.3	-0.8	-1.5	-1.3	-0.5	-1.5	-1.7	-0.4	-0.6	-1.0	-1.0
Medication: Bendroflumethiazide	0.3	0.4	1.4	-0.3	-0.8	-0.7	-0.4	-0.6	-0.7	-0.4	-0.5	-0.7	-0.1	1.2	-0.5
Medication: Atorvastatin	0.3	0.4	0.9	-0.0	-0.6	-0.5	0.0	-0.9	-1.0	-0.4	-0.0	-0.8	-0.7	-0.8	-0.4
Blood Red Count	0.2	2.0	5.6	-2.4	-1.1	-0.3	-2.1	-1.2	-0.4	-1.0	-2.4	-0.5	0.4	-1.5	-1.5
Height	0.2	3.4	8.1	2.8	1.4	-0.6	2.6	1.5	0.5	-0.1	2.6	2.2	0.5	1.5	2.9
Waist Hip Ratio (WHR)	0.2	0.7	3.5	-0.6	-0.1	-0.3	-1.0	-0.1	1.0	0.8	-0.9	0.8	0.5	-1.9	0.3
Systolic Blood Pressure	0.2	1.2	4.3	-0.5	0.9	2.1	-0.1	0.6	1.2	1.3	-0.1	0.4	2.0	1.4	-0.2
Smoking Status	0.2	0.6	1.7	-0.9	-0.5	-1.0	-1.0	-0.8	-0.1	-0.5	-1.0	-0.3	-0.3	-1.3	-0.3
Cardiovascular Disease	0.2	0.7	2.4	-0.6	0.3	1.2	-0.8	-0.1	1.1	1.0	-0.8	0.4	1.6	0.1	-0.1
Lung FEV1/FVC ratio	0.2	1.0	2.9	-1.6	-0.6	0.5	-1.6	-0.5	-0.0	-0.2	-1.7	0.7	0.4	-0.9	-1.1
Angina	0.2	0.3	1.4	0.5	0.4	1.2	0.4	0.3	0.2	0.4	0.6	-0.3	0.6	0.4	-0.0
Leg fat-free mass (left)	0.2	0.9	2.0	-1.2	-1.1	-0.7	-1.1	-1.0	-0.4	-1.4	-1.4	-0.3	-0.4	-0.8	-0.6
Fed-up feelings	0.2	0.3	0.9	0.4	-0.3	-0.9	0.4	-0.1	-0.6	-0.9	0.3	-0.5	-0.0	0.9	0.3
Relative age voice broke	0.2	0.3	0.8	-0.5	0.4	-0.0	-0.6	0.3	0.6	0.3	-0.4	0.9	0.6	0.8	0.3
High blood pressure (mother)	0.2	0.3	0.6	0.7	0.5	0.6	0.6	0.6	0.3	0.5	0.6	0.3	0.8	0.7	0.4
Leg predicted mass (left)	0.2	1.0	2.3	-1.2	-1.1	-0.8	-1.2	-1.1	-0.5	-1.4	-1.5	-0.3	-0.5	-0.8	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	0.4	0.7	0.3	0.5	0.7	0.8	0.5	0.5	0.5	0.4	0.2	0.8
Father’s age at death	0.2	0.2	0.9	0.0	0.5	0.1	0.3	0.5	0.5	0.5	-0.1	0.9	0.7	-0.5	0.5
Hair/balding pattern: Pattern 3	0.2	0.4	2.8	-0.3	-0.0	0.9	-0.2	0.1	-0.1	0.1	-0.3	-0.2	0.3	1.7	-0.6
Number of live births	0.2	0.3	0.7	-0.9	0.2	0.3	-0.8	0.2	0.4	0.7	-0.7	0.8	-0.2	-0.2	-0.3
Illnesses of mother	0.2	0.3	0.7	0.6	0.4	-0.8	0.5	0.4	-0.0	0.4	0.6	0.5	-0.5	-0.5	0.8
Standing height	0.2	2.0	5.7	2.4	0.6	-1.1	2.3	0.9	-0.0	-0.6	2.0	1.1	-0.2	0.2	2.2
Loud music exposure frequency	0.2	0.2	0.6	0.8	0.2	-0.0	0.5	0.2	0.2	0.0	0.3	0.1	0.2	0.8	0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	0.5	0.6	0.2	0.6	0.5	0.4	0.5	0.6	0.9	0.3	0.4	0.6
Comparative body size at age 10	0.2	0.6	4.5	-0.0	-0.2	-0.2	0.2	0.4	-0.5	-0.9	-0.0	0.1	-1.1	2.1	-0.4
Pulse wave peak to peak time	0.2	0.3	0.6	0.6	0.5	0.8	0.5	0.4	0.2	0.6	0.7	0.6	-0.0	0.6	0.4
Medication: Ibuprofen	0.2	0.2	0.8	0.4	-0.2	-0.9	0.4	-0.3	-0.6	-0.8	0.1	-0.1	-0.0	-0.0	-0.1
Medication: Allopurinol	0.2	0.3	0.6	0.6	0.7	-0.5	0.3	0.7	0.4	0.4	0.7	0.7	-0.1	0.4	0.7
Pulse rate, automated reading	0.2	0.7	2.3	0.9	-0.2	-1.4	0.8	-0.0	-0.5	-0.1	0.8	-1.0	-1.1	1.5	0.2
Leg fat-free mass (right)	0.2	1.2	2.6	-1.3	-1.2	-0.8	-1.3	-1.2	-0.5	-1.4	-1.6	-0.4	-0.6	-0.9	-0.8
Mood swings	0.2	0.4	0.9	0.9	-0.1	-1.0	0.8	-0.0	-0.7	-0.3	0.7	-0.8	-0.5	0.4	0.5
Loneliness, isolation	0.2	0.2	2.0	0.3	0.1	-0.5	0.3	0.3	-0.1	-0.1	0.2	0.3	0.0	1.4	0.5
Medication for cholesterol	0.2	0.2	0.5	0.6	0.3	-0.5	0.7	0.5	-0.4	-0.5	0.6	0.1	-0.7	-0.3	0.4
Osteoarthritis (self-reported)	0.2	0.3	1.0	0.2	0.6	0.8	0.2	0.4	0.6	0.4	0.2	0.8	1.0	-0.1	0.3
Medication: Blood pressure	0.2	0.4	1.3	-0.8	-0.3	0.8	-1.0	-0.6	0.5	0.4	-0.6	-0.1	1.1	0.0	-0.6
Medication: Paracetamol	0.2	0.2	1.3	0.6	0.2	0.3	0.5	-0.1	-0.5	-0.4	0.6	-0.2	0.5	1.1	0.0
Average weekly beer plus cider intake	0.2	0.3	0.5	-0.7	-0.3	-0.7	-0.4	-0.4	-0.6	-0.6	-0.4	-0.5	-0.4	0.6	-0.7
Myopia	0.2	0.3	0.9	0.6	0.6	0.8	0.9	0.4	-0.1	0.4	0.6	0.2	0.4	0.2	0.3
Basal cell carcinoma (self-reported)	0.2	0.3	0.9	-0.2	0.2	1.0	-0.1	0.5	0.4	0.5	-0.1	0.3	0.8	0.8	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	-0.5	-0.3	0.4	-0.5	-0.9	-0.3	-0.1	-0.5	-0.4	0.8	0.0	-0.7
Alcohol drinker status: Previous	0.2	0.3	1.2	-0.0	-0.3	0.4	0.1	-0.3	-0.5	-0.9	0.1	-1.1	-0.1	-0.4	-0.4
Depressed Affect (Nagel 2018)	0.1	0.2	0.9	0.6	0.2	-1.0	0.5	0.4	-0.3	-0.6	0.3	0.1	-0.1	0.4	0.8
Depression (Nagel 2018)	0.1	0.1	0.3	0.4	0.2	-0.1	0.5	0.2	0.1	-0.6	0.3	0.0	0.0	0.3	0.4
Ulcerative Colitis (UC)	0.1	0.3	1.2	0.6	0.3	-0.5	0.7	-0.2	-0.7	-0.2	1.1	-0.1	-0.1	0.5	-0.3
Heel T-Score	0.1	1.0	2.3	-1.5	-0.7	0.8	-1.5	-0.7	0.4	0.4	-1.2	-0.9	-0.5	-1.3	-1.4
Tanning	0.1	1.0	4.0	-1.4	-0.2	-0.1	-1.6	-0.3	0.9	0.4	-1.3	0.6	-0.1	-2.0	-0.3
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.7	-0.1	-0.4	-0.5	-0.1	-0.2	-0.2	-0.8	-0.1	-0.3	-0.2	0.2	0.2
Systolic blood pressure, automated reading	0.1	0.4	1.3	-1.1	-0.3	0.3	-1.1	-0.4	0.2	0.2	-1.0	-0.3	0.6	0.3	-0.8
Supplements: Zinc	0.1	0.1	0.7	-0.1	-0.3	-0.3	-0.0	-0.5	-0.8	-0.2	-0.2	-0.5	-0.4	-0.2	-0.4
Townsend deprivation index at recruitment	0.1	0.2	0.7	-0.0	0.4	0.6	-0.2	0.2	0.7	0.1	0.1	0.5	0.8	0.0	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.2	-0.2	0.1	-0.4	-0.3	0.1	-0.3	-0.5	0.3	0.5	0.4	0.0
High blood pressure	0.1	0.3	1.2	-0.1	0.5	0.8	-0.0	0.3	0.7	0.6	0.0	0.3	1.1	0.5	0.2
Medication: Levothyroxine sodium	0.1	0.1	0.5	0.2	0.1	-0.2	0.1	0.3	0.0	-0.4	-0.1	0.1	-0.7	-0.5	0.1
Sitting height	0.1	0.7	1.9	1.4	0.4	-0.4	1.4	0.2	0.1	-0.7	1.1	0.9	0.3	0.8	1.2
Number of incorrect matches in round	0.1	0.2	0.8	-0.3	-0.1	0.6	-0.6	-0.2	0.3	0.4	-0.5	-0.0	0.9	-0.5	0.0
Mouth/teeth dental problems	0.1	0.2	1.3	0.0	0.6	0.6	0.3	0.3	0.3	0.3	0.1	0.3	-0.2	-1.2	0.0
Alcohol intake versus 10 years previously	0.1	0.2	0.6	-0.4	-0.5	-0.3	-0.4	-0.7	-0.3	-0.5	-0.4	-0.8	0.0	-0.3	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	-0.1	0.0	-0.5	-0.0	-0.2	-0.1	-0.6	-0.2	0.3	0.0	-0.3	-0.1
Pulse wave reflection index	0.1	0.1	0.4	-0.5	-0.2	-0.2	-0.5	-0.1	0.4	0.2	-0.5	0.2	0.1	-0.7	0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.4	-0.1	-0.5	-0.4	-0.2	-0.6	-0.6	-0.1	0.0	-0.4	-0.6	-0.2	-0.7
Blood clot in the leg (DVT)	0.1	0.2	1.3	0.0	0.2	0.7	-0.0	-0.4	0.1	0.2	0.1	0.0	1.1	0.4	-0.1
Headache pain in last month	0.1	0.2	0.9	0.5	0.4	-0.1	0.5	-0.1	-0.2	-1.0	0.4	0.0	0.3	0.7	0.2
Gout (self-reported)	0.1	0.2	1.4	-0.3	0.0	-1.2	-0.4	0.2	-0.1	-0.5	-0.2	0.1	-0.6	-0.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.9	-0.6	-0.4	-0.5	-0.8	-0.1	0.0	-0.5	-0.9	-0.1	-0.4	-0.6	-0.4
Age at first live birth	0.1	0.1	0.6	-0.4	0.2	0.2	-0.3	-0.2	0.3	-0.1	-0.3	0.4	0.4	-0.8	-0.1
Medication for pain relief, constipation, heartburn	0.1	0.1	0.8	0.3	-0.3	-0.9	0.1	-0.1	-0.3	-0.2	0.1	-0.2	-0.3	0.2	0.2
Neck or shoulder pain in last month	0.1	0.1	0.9	-0.1	0.1	-0.4	-0.0	0.1	0.1	0.0	-0.2	-0.3	-0.3	1.0	0.2
Medication: Blood pressure	0.1	0.1	0.5	0.2	0.4	0.4	0.1	0.4	0.4	0.3	0.2	-0.0	0.2	0.7	0.2
Heart disease (mother)	0.1	0.1	0.4	-0.3	-0.2	0.6	-0.1	-0.2	0.1	-0.4	-0.2	-0.6	0.3	-0.3	-0.5
Age at last live birth	0.1	0.1	0.5	-0.2	0.5	-0.0	-0.0	0.3	0.6	0.5	-0.1	0.7	-0.1	-0.3	0.3
Medication: Aspirin	0.1	0.1	0.4	-0.1	0.0	0.6	-0.1	-0.1	0.6	0.6	0.0	-0.2	0.4	-0.5	-0.1
Hypertension (Self-reported)	0.1	0.4	1.1	-0.0	0.6	0.9	0.0	0.4	0.6	0.7	0.1	0.2	1.0	1.1	0.2
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.3	-0.1	-0.3	-0.4	0.0	-0.3	0.0	-0.6	0.2	-0.6	-0.4	0.5	-0.1
Ever smoked	0.1	0.2	1.0	-0.0	0.1	-1.0	-0.1	0.5	0.4	0.3	-0.2	0.4	-0.3	-0.4	0.8
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.4	0.0	-0.4	-0.9	-0.1	-0.1	-0.6	-0.6	-0.1	0.1	-1.2	-0.7	-0.1
Pain experienced in last month	0.1	0.2	0.7	0.2	0.0	-0.1	0.2	0.0	-0.1	0.9	0.6	0.2	-0.7	-0.3	0.1
Hair Pigment	0.0	1.2	2.4	1.3	1.1	0.3	1.1	1.2	1.1	0.7	1.6	1.0	0.5	1.1	1.5
Heart attack	0.0	0.1	0.2	-0.0	-0.1	0.0	-0.1	-0.4	0.1	0.0	0.0	-0.4	-0.2	-0.4	-0.3
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	-0.1	0.0	0.2	-0.2	-0.3	0.3	0.1	0.0	-0.3	-0.1	-0.4	-0.3

Hub : Genes

FRAT2

Models

Trait associations