Hub : Genes

SLC11A2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.4680	0.0520	0.0e+00	0.335	NA	0.431	NA	0.410	8.2e-26	NA	4.6e-35	NA	6.9e-33
2	GTEx	Nerve Tibial	0.0970	0.0391	3.0e-03	-0.001	NA	0.043	NA	0.013	4.2e-01	NA	5.1e-04	NA	3.6e-02
3	GTEx	Testis	0.1700	0.0570	1.5e-05	0.127	NA	0.115	NA	0.104	2.9e-06	NA	9.2e-06	NA	2.5e-05
4	YFS	Blood	0.0689	0.0178	5.7e-14	0.038	0.055	0.054	0.053	0.057	1.2e-12	2.4e-17	2.8e-17	5.9e-17	4.2e-18
5	TCGA	Breast Invasive Carcinoma	0.0253	0.0130	6.2e-05	0.017	0.015	0.014	NA	0.012	1.4e-04	3.0e-04	6.3e-04	NA	1.2e-03
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0688	0.0355	5.8e-05	0.014	0.039	0.022	NA	0.023	8.6e-03	2.9e-05	1.5e-03	NA	1.2e-03
7	TCGA	Brain Lower Grade Glioma	0.1142	0.0487	2.2e-10	0.114	0.094	0.103	NA	0.109	7.0e-13	8.8e-11	9.0e-12	NA	2.3e-12
8	TCGA	Lung Adenocarcinoma	0.0286	0.0192	9.4e-03	0.019	0.015	0.005	NA	0.013	2.2e-03	5.7e-03	8.5e-02	NA	9.0e-03
9	TCGA	Lung Squamous Cell Carcinoma	0.0348	0.0198	1.8e-03	0.013	0.020	0.017	NA	0.004	1.0e-02	2.0e-03	4.4e-03	NA	9.2e-02
10	TCGA	Prostate Adenocarcinoma	0.0712	0.0401	8.5e-06	0.049	0.055	0.055	NA	0.048	7.2e-06	2.1e-06	2.0e-06	NA	8.4e-06
11	TCGA	Testicular Germ Cell Tumors	0.1660	0.0850	2.1e-03	0.086	0.049	0.042	NA	0.078	5.6e-04	8.2e-03	1.3e-02	NA	1.0e-03
12	TCGA	Thyroid Carcinoma	0.0630	0.0310	4.7e-05	0.047	0.038	0.045	NA	0.041	2.1e-05	1.3e-04	2.9e-05	NA	6.3e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.8	1.3	4.3	1.7	-1.0	0.2	1.6	1.0	-0.1	0.6	1.8	0.6	2.1	-0.2	-0.0
Bipolar Disorder or Schizophrenia	0.4	1.1	2.8	1.3	-0.8	-0.3	1.5	1.0	-0.0	1.0	1.7	0.4	1.7	-0.7	-0.3
Depressed Affect (Nagel 2018)	3.9	8.2	15.4	-3.9	-1.0	-1.3	-2.6	-2.9	-3.4	0.3	-3.6	-3.6	-3.2	-1.9	-3.7
Depression (Nagel 2018)	0.1	0.2	0.5	-0.1	-0.7	-0.4	-0.5	-0.2	-0.5	0.4	-0.5	-0.3	-0.3	-0.5	-0.6
Intelligence (Savage-Jansen 2018)	0.8	2.6	6.9	1.8	1.8	2.6	1.7	1.9	1.3	-1.5	1.1	1.6	0.1	1.7	0.4
Neuroticism (Nagel 2018)	2.3	5.3	11.2	-3.3	-0.7	-0.5	-2.0	-2.0	-2.5	-0.0	-2.9	-3.0	-2.9	-1.1	-3.3
Schizophrenia (2018)	0.1	0.3	0.7	0.3	-0.4	-0.6	0.7	0.4	0.0	0.9	0.7	-0.1	0.5	-0.7	-0.4
Schizophrenia vs Biploar Disorder	0.9	1.2	5.0	-0.1	-0.3	-2.0	-0.6	0.4	0.6	2.2	-0.0	0.3	0.3	-2.0	0.1
Worry (Nagel 2018)	1.7	3.5	6.8	-2.6	-2.0	-1.3	-1.8	-1.8	-1.5	0.3	-2.2	-2.3	-2.2	-1.2	-2.1
Alzheimer’s Disease (in mother)	1.3	1.6	7.1	0.4	2.7	-0.1	1.5	0.4	-1.3	1.2	0.7	-0.7	0.4	-1.4	-1.8
Alzheimer’s Disease (in father)	0.3	0.3	1.0	-0.7	0.5	-0.1	0.1	0.1	-0.4	1.0	0.1	-0.4	0.0	-0.8	-0.7
Alzheimer’s Disease (including proxy)	1.6	2.3	9.0	0.6	3.0	0.2	1.9	1.0	-1.0	2.1	1.1	-0.3	0.9	-1.7	-2.0
Crohns Disease (2017)	0.6	1.3	7.4	-0.2	-0.2	-1.4	0.7	0.1	-1.1	2.7	0.1	0.3	0.4	-2.0	0.0
Irritable Bowel Disease (IBD)	0.2	0.5	2.0	0.3	-1.3	-0.2	0.4	0.3	0.0	0.6	0.4	0.8	0.4	-0.0	1.4
Ulcerative Colitis (UC)	0.8	1.5	5.6	0.3	-2.4	0.4	-0.4	-0.1	0.9	-1.4	0.2	0.9	-0.0	1.6	2.3
Major Depression (MDD)	0.2	0.2	0.8	-0.3	0.9	0.5	-0.0	0.3	0.3	-0.5	-0.3	0.0	-0.8	0.3	-0.3
Reaction Time	0.8	1.6	3.2	-1.8	-1.3	-1.4	-1.8	-1.0	-0.2	0.4	-1.3	-1.3	-1.4	-1.2	-0.9
Verbal and Numeric Reasoning (VNR)	1.1	2.6	7.3	1.7	1.9	2.7	1.5	1.7	1.1	-1.7	0.9	1.5	-0.2	2.1	0.5
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	1.2	1.6	3.2	-1.4	-0.8	-1.3	-1.1	-1.5	-1.1	0.4	-1.4	-1.8	-1.3	-1.0	-1.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.9	1.3	3.8	-0.9	-1.9	-1.8	-1.4	-1.6	-0.6	0.9	-0.7	-0.9	-0.1	-0.5	0.7
Bipolar Disorder (2011)	1.3	1.2	4.5	1.3	1.0	1.2	2.1	1.1	-1.0	-0.2	1.1	-0.1	0.6	-0.1	-1.6
Body Mass Index (BMI) (2010)	0.5	0.7	1.3	1.1	0.6	1.0	1.1	1.0	0.4	-0.5	1.0	0.9	0.9	0.5	0.2
Coronary Artery Disease (CAD)	1.3	1.6	2.5	1.6	1.3	1.5	1.4	1.4	0.9	-1.5	1.1	1.3	0.4	1.3	0.6
Crohns Disease (2012)	0.5	0.8	1.8	1.0	0.7	0.3	1.3	0.8	-0.3	1.3	1.1	0.8	1.3	-0.5	0.3
Mean Putamen Volume	1.4	1.6	3.7	-1.7	-0.4	-0.6	-0.7	-1.2	-1.6	0.3	-1.7	-1.3	-1.9	-0.8	-1.3
Fasting Glucose	0.4	0.5	1.2	0.8	0.9	0.8	0.6	-0.0	-0.3	-0.8	0.8	0.1	1.1	1.0	0.2
HbA1C	4.0	4.5	8.6	2.2	1.3	2.9	1.8	2.6	2.1	-2.1	2.1	2.4	1.1	2.6	1.2
HDL Cholesterol	0.2	0.3	1.3	-0.2	1.1	0.8	0.1	0.4	0.2	-0.2	-0.2	-0.2	-0.6	0.2	-0.9
LDL Cholesterol	0.7	1.0	4.3	-0.3	1.0	1.2	-0.5	-0.3	1.0	-2.1	-0.1	-0.1	-0.3	1.9	0.8
Lupus	0.3	0.5	1.7	0.0	-0.5	-1.3	-0.3	0.3	0.8	1.2	0.5	0.3	0.8	-1.0	0.3
Neuroticism (2016)	1.7	2.5	4.5	-1.9	-0.2	-1.0	-1.4	-1.6	-2.0	0.3	-2.1	-2.0	-1.8	-1.0	-2.0
Primary Biliary Cirrhosis	0.6	0.8	3.0	0.5	1.0	0.5	1.4	0.8	-0.8	0.7	0.7	-0.4	0.0	-0.8	-1.7
Rheumatoid Arthritis	1.5	2.0	5.7	-1.1	1.4	-0.7	0.5	-0.6	-2.1	2.0	-0.3	-1.7	0.1	-1.8	-2.4
Schizophrenia (2014)	0.4	0.9	3.2	1.4	0.4	-0.2	1.8	1.0	-0.2	1.0	1.4	0.3	1.0	-0.7	-0.6
Triglycerides	2.5	4.0	7.9	2.1	1.2	1.7	1.4	2.0	2.8	-1.3	2.6	2.2	2.4	1.9	1.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.1	0.9	-0.0	-0.1	0.6	0.9	0.6	0.7	0.9	1.0	1.1	-0.2	0.6
Ulcerative Colitis	0.9	1.2	5.1	-0.2	-1.1	0.6	-0.9	-0.8	0.5	-2.3	-0.5	-0.1	-0.8	1.8	1.6
Blood Eosinophil Count	1.5	11.9	36.7	3.2	1.6	6.1	4.0	4.6	3.1	-2.5	3.6	3.4	1.8	3.5	0.4
Blood Platelet Count	0.6	7.0	33.1	0.8	-1.8	5.8	3.7	2.7	1.1	-2.4	2.6	1.5	0.9	2.9	-0.5
Blood Red Count	0.2	1.6	6.3	-1.0	-0.4	-2.5	-2.0	-1.7	-0.0	1.0	-1.1	-0.6	0.2	-0.9	1.2
Blood White Count	3.4	25.0	57.0	5.6	4.3	7.5	7.1	6.9	3.4	-2.4	5.8	5.0	3.2	3.3	0.0
Heel T-Score	1.8	14.7	43.8	-2.7	2.2	-4.9	-0.4	-1.9	-4.2	5.5	-1.8	-3.8	-1.0	-6.6	-5.2
BMI	0.1	0.8	3.3	-0.1	0.3	0.2	0.1	-0.8	-1.8	0.1	-1.1	-1.1	-0.7	-0.8	-1.6
Height	1.3	24.2	75.0	-4.4	-2.4	-8.7	-4.8	-5.6	-4.6	5.2	-4.9	-4.5	-2.5	-5.9	-1.6
Waist Hip Ratio (WHR)	0.7	3.2	8.4	0.7	0.1	2.5	-0.0	1.4	2.9	-2.7	0.8	1.8	-0.1	2.8	1.8
Systolic Blood Pressure	0.2	1.1	4.3	-0.0	2.1	-0.4	0.2	-0.2	-0.6	-0.7	-0.7	-1.1	-1.8	-0.2	-1.6
Smoking Status	0.1	0.3	1.1	1.1	0.2	0.5	0.8	0.6	0.3	-0.4	0.7	0.6	0.4	0.6	0.5
Allergy or Eczema	0.5	1.2	3.5	0.4	1.6	-1.2	0.4	0.4	0.0	1.7	1.4	-0.1	1.9	-1.4	-0.4
Cardiovascular Disease	0.6	2.0	5.7	-0.6	0.7	1.4	-0.1	-0.5	-0.9	-2.3	-1.3	-1.4	-2.4	1.3	-1.9
Hypothyroidism (self reported)	0.7	1.7	3.1	1.2	1.5	0.3	1.6	1.7	0.9	0.8	1.8	1.7	1.7	-0.6	0.5
Respiratory disease	0.3	0.6	3.5	0.1	0.4	0.1	0.9	0.5	-0.7	0.6	0.3	-0.5	-0.2	-1.1	-1.9
Type 2 Diabetes (T2D) (2018)	1.8	3.3	6.4	2.1	1.8	1.5	1.2	2.0	2.5	-0.4	2.3	1.9	2.1	1.6	1.4
Lung FEV1/FVC ratio	0.1	0.6	2.2	-0.9	-0.1	0.3	-0.9	-0.1	-0.6	-0.1	-1.5	-0.2	-1.2	-0.6	-1.1
Lung FVC	0.4	1.8	5.7	-0.0	2.2	2.1	0.1	-0.2	0.3	-2.3	-0.3	-0.1	-1.0	2.4	0.5
Neuroticism	1.7	4.1	7.9	-2.8	0.4	-0.1	-1.7	-2.2	-2.3	-0.9	-2.7	-2.6	-2.6	-0.3	-2.5
Chronotype (morning person)	0.4	0.9	3.3	-0.1	-1.2	-1.3	-0.9	-1.8	-1.3	0.1	-1.0	-0.7	0.2	0.2	0.7
Hair Pigment	0.0	0.7	2.5	-0.3	-0.0	0.3	-1.2	-0.5	0.9	-1.6	-0.6	-0.6	-1.1	1.1	0.1
Tanning	0.1	0.8	2.7	0.3	-1.5	0.6	-0.5	-0.3	0.5	-1.0	0.1	0.6	0.5	1.5	1.6
Hand grip strength (left)	0.7	1.8	5.1	1.5	1.9	-0.2	0.7	0.5	1.0	0.5	1.3	1.5	2.3	0.7	2.0
Number of treatments/medications taken	0.6	1.0	3.9	0.4	-0.3	1.9	0.3	0.7	0.6	-2.0	0.2	0.4	-0.7	1.7	-0.2
Average weekly spirits intake	1.6	2.0	4.7	-1.8	-0.4	0.6	-1.7	-1.6	-0.1	-2.2	-1.6	-1.2	-1.6	1.7	0.2
Sensitivity / hurt feelings	0.2	0.3	2.4	-0.4	0.2	0.6	0.2	0.2	-0.5	-0.1	-0.1	-0.6	-0.4	-0.4	-1.6
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.2	-1.2	-1.5	-1.1	-1.4	-0.9	-0.7	0.8	-1.5	-0.5	-0.9	-0.8	-0.1
Hearing difficulty/problems: Yes	0.7	1.0	5.4	0.4	1.1	0.9	1.0	0.2	-1.1	-0.7	0.2	-1.2	-0.6	0.1	-2.3
Relative age of first facial hair	0.2	0.4	1.3	-1.2	-1.1	-0.7	-0.8	-0.6	0.3	-0.3	-0.2	-0.5	0.0	-0.0	0.3
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	7.7	-0.9	-0.8	1.0	-1.8	-1.1	0.0	-2.8	-1.6	-0.6	-1.8	1.8	0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.9	0.8	-0.9	0.1	0.4	-0.0	-0.5	0.1	0.4	0.0	0.5	0.1	0.1
Ever had hysterectomy (womb removed)	1.4	1.5	3.4	-0.6	1.9	-1.5	0.0	-0.8	-1.5	1.6	-0.5	-1.3	-0.1	-1.8	-1.4
Systolic blood pressure, automated reading	0.6	1.8	4.7	-1.1	2.2	-0.7	-0.6	-1.0	-1.0	-0.5	-1.1	-1.9	-1.7	-0.6	-2.1
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	3.7	1.7	1.5	0.4	1.9	1.4	0.5	0.9	1.9	1.1	1.8	-0.1	0.3
Angina	1.1	1.5	6.2	-0.2	-1.3	1.0	-1.1	-0.2	1.2	-2.5	-0.6	0.3	-1.2	1.7	1.0
Medication for hormone replacement therapy	1.0	1.1	2.6	-1.0	-1.4	-0.4	-0.4	-1.1	-1.5	0.1	-1.4	-1.2	-1.6	-0.5	-1.0
Vitamin and mineral supplements	1.1	1.5	3.5	0.9	1.5	0.7	0.9	1.6	1.8	0.3	1.9	1.1	1.8	0.3	0.5
Supplements: Zinc	1.3	1.4	3.7	1.7	0.2	0.3	1.1	1.2	1.0	0.2	1.3	1.9	1.5	0.3	1.8
Medication: Co-codamol	1.0	1.1	2.7	-1.1	-1.6	-1.6	-1.1	-1.5	-0.7	0.5	-1.0	-0.7	-0.5	-0.8	0.6
Medication: Metformin	1.1	1.5	2.9	1.5	1.3	1.1	1.5	1.4	1.0	-0.2	1.7	1.2	1.5	0.8	0.6
Diabetes (father)	0.4	0.4	1.0	-0.6	0.5	0.6	-0.3	-0.5	-0.4	-0.8	-0.7	-0.8	-1.0	0.9	-0.7
Diabetes (mother)	0.2	0.3	0.9	-0.2	0.2	0.5	-0.1	-0.5	-0.4	-0.9	-0.1	-0.9	0.1	0.6	-0.9
Severe depression (siblings)	4.8	5.4	17.4	1.4	0.1	3.6	1.1	1.6	2.5	-3.8	1.4	1.8	0.3	4.2	1.7
Pack years adult smoking proportion	0.6	0.8	2.1	1.2	-0.1	-0.8	-0.3	0.5	1.3	0.4	0.8	1.1	1.4	-0.1	1.4
Impedance of leg (right)	0.6	3.1	12.2	-0.4	-1.6	-3.5	-0.3	-0.2	-0.7	3.0	0.1	-0.8	0.2	-3.3	-1.1
Leg fat-free mass (left)	0.6	3.0	6.9	-1.9	0.3	-1.1	-1.6	-2.5	-2.4	0.1	-2.6	-2.1	-1.7	-0.7	-1.2
Trunk fat percentage	0.6	2.3	7.2	0.0	-0.7	-1.4	0.3	-0.2	-2.2	2.0	-0.8	-1.2	-0.6	-2.7	-2.6
Hand grip strength (right)	0.6	1.6	4.9	1.4	1.5	-0.6	0.7	0.5	1.1	0.9	1.4	1.3	2.2	0.3	1.9
Townsend deprivation index at recruitment	2.9	4.0	9.2	-2.2	-0.5	-3.0	-1.6	-2.0	-1.9	2.5	-1.8	-2.1	-1.1	-2.6	-1.2
Current tobacco smoking	0.1	0.2	0.5	0.2	0.7	0.6	0.4	0.4	0.2	-0.2	0.1	0.7	-0.1	0.4	0.6
Average weekly fortified wine intake	1.5	1.7	4.5	0.3	-1.2	1.7	-0.1	0.7	1.8	-1.6	0.7	1.2	0.6	2.1	1.7
Maternal smoking around birth	0.3	0.4	1.1	-0.9	0.3	-0.3	-0.7	-0.6	-0.3	0.3	-0.8	-0.9	-1.1	-0.3	-0.5
Fed-up feelings	1.3	2.3	4.6	-2.0	-0.6	-0.6	-1.2	-1.7	-2.1	-0.1	-1.9	-2.0	-1.5	-1.0	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.5	0.2	-1.3	-1.1	-0.4	0.0	-0.3	1.6	0.2	0.0	0.9	-1.2	-0.0
Relative age voice broke	0.4	0.5	1.4	0.2	0.8	0.8	0.5	1.1	1.2	-0.4	0.6	1.0	0.7	0.3	0.3
Taking other prescription medications	0.7	1.0	4.0	-1.0	-0.3	1.0	-1.0	-0.2	0.6	-2.0	-0.9	-0.1	-1.6	1.1	-0.2
Age when periods started (menarche)	0.8	1.8	5.0	-1.6	0.1	-1.4	-0.2	-0.3	-1.0	1.9	-0.8	-1.3	-1.1	-2.2	-2.0
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.5	-0.1	-0.8	-1.9	0.1	-0.8	-1.5	1.9	-0.4	-0.7	0.1	-1.8	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	5.5	-1.0	1.0	-1.7	-0.3	-0.9	-2.1	1.3	-1.4	-1.6	-1.5	-2.3	-2.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.9	0.5	-0.3	0.7	0.3	0.9	0.9	-0.0	0.2	1.0	0.0	0.3	0.4
Qualifications: CSEs or equivalent	0.6	0.8	4.0	-1.0	-2.0	-0.7	-0.8	-1.0	-0.8	0.1	-1.0	-0.6	-0.7	-0.4	-0.1
Serious illness, injury or assault to yourself	3.1	3.7	9.6	-2.3	-1.2	0.3	-1.5	-2.2	-1.9	-1.9	-2.8	-2.0	-3.1	0.7	-1.2
High blood pressure	0.5	1.3	3.6	0.1	0.6	1.3	0.2	-0.3	-1.0	-1.8	-0.9	-1.0	-1.9	1.2	-1.5
Hayfever, allergic rhinitis or eczema	1.0	2.2	5.6	-0.1	1.7	-1.7	0.7	-0.3	-1.5	2.4	0.9	-1.3	1.4	-2.4	-1.8
Multivitamins +/- minerals	0.4	0.5	1.2	-0.4	0.1	-0.6	-0.2	-0.7	-1.1	0.7	-0.9	-0.7	-0.7	-0.8	-0.9
Stomach or abdominal pain in last month	2.4	2.9	5.4	-2.3	-1.5	-1.5	-2.2	-1.9	-1.5	0.7	-2.3	-1.7	-2.0	-1.2	-1.0
Supplements: Glucosamine	1.7	2.3	4.5	-1.6	-1.4	-1.7	-2.0	-2.1	-1.4	0.7	-2.1	-1.3	-1.3	-0.8	0.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.7	0.3	-0.1	0.6	-0.3	0.8	1.6	-0.9	0.5	0.9	0.2	0.8	0.8
Medication: Atenolol	0.3	0.3	2.1	0.0	-1.4	-0.5	-0.9	-0.4	-0.0	-0.3	-0.4	-0.5	-0.5	-0.2	-0.2
Medication: Levothyroxine sodium	1.1	1.9	5.5	1.5	1.6	0.7	2.4	1.8	0.1	0.7	1.8	1.4	1.6	-0.7	-0.3
Sitting height	1.4	9.9	22.7	-2.6	-0.7	-4.8	-3.6	-4.7	-3.5	1.3	-3.9	-3.8	-2.3	-2.1	-1.1
Chronic bronchitis/emphysema (father)	0.3	0.4	1.4	1.2	-0.4	0.4	0.8	0.6	-0.0	0.0	0.9	0.2	0.8	-0.3	-0.7
High blood pressure (mother)	1.3	1.8	10.0	-0.0	0.3	2.2	-0.2	0.0	0.2	-3.2	-0.6	-0.5	-1.2	1.9	-1.0
Body mass index (BMI)	0.1	0.5	1.5	-0.0	0.1	0.9	0.1	-0.3	-1.2	-0.5	-0.9	-0.5	-0.7	0.0	-1.2
Impedance of leg (left)	1.0	4.7	18.3	-0.9	-2.1	-4.3	-0.9	-0.6	-0.9	3.6	-0.4	-1.0	0.1	-3.9	-1.1
Leg predicted mass (left)	0.6	3.0	7.2	-1.9	0.3	-1.1	-1.7	-2.5	-2.3	0.0	-2.7	-2.1	-1.8	-0.6	-1.1
Trunk fat mass	0.6	2.6	6.7	-0.5	-0.8	-1.8	-0.4	-0.9	-2.4	2.0	-1.4	-1.4	-0.8	-2.6	-2.1
Waist circumference	0.2	0.6	1.6	-0.8	-0.3	0.0	-1.0	-0.7	-0.8	-0.3	-1.3	-0.8	-0.9	-0.3	-1.0
Number of incorrect matches in round	0.3	0.5	1.6	-1.0	-0.5	-1.3	-1.1	-0.6	0.4	0.4	0.1	-0.7	0.3	-0.4	0.2
Past tobacco smoking	0.2	0.3	1.2	-0.4	1.1	0.4	0.5	0.7	0.1	0.7	0.3	0.2	0.4	-0.7	-0.7
Alcohol usually taken with meals	1.6	2.6	7.8	1.0	0.0	2.8	1.6	1.9	1.5	-1.4	1.0	2.3	0.3	2.0	1.3
Nervous feelings	0.6	1.2	2.1	-1.4	-0.8	-0.4	-0.8	-1.3	-1.4	-0.1	-1.4	-1.4	-1.4	-0.4	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.3	1.9	5.5	-1.5	-1.0	0.3	-0.9	-1.2	-1.4	-1.0	-1.8	-1.7	-2.3	0.2	-1.8
Hearing difficulty/problems with background noise	0.4	0.6	2.5	0.4	1.6	1.1	0.9	0.6	-0.3	-0.5	0.3	-0.3	-0.3	0.3	-1.4
Hair/balding pattern: Pattern 2	0.4	0.5	1.6	0.1	-0.4	0.7	-0.6	0.3	1.3	-1.2	0.3	0.4	0.2	1.2	0.7
Had menopause	0.3	0.3	1.7	-0.3	1.3	0.3	-0.7	-0.4	0.4	-0.9	-0.3	-0.4	-0.4	0.6	-0.0
Had other major operations	1.3	1.6	3.9	1.4	-0.2	-0.1	0.5	1.4	1.5	1.0	1.3	2.0	2.0	-0.2	1.6
Forced vital capacity (FVC)	0.7	2.8	4.8	-1.5	2.2	-2.0	-0.9	-1.9	-2.0	1.5	-1.6	-2.0	-1.0	-1.5	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	10.0	-0.3	1.8	-1.1	1.2	0.2	-2.4	2.0	-0.4	-1.1	-0.7	-2.9	-3.2
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	7.5	0.6	1.4	2.7	0.7	0.8	0.9	-2.6	0.5	0.2	-0.4	2.5	-0.4
Qualifications: None of the above	1.3	2.9	7.5	-1.7	-2.7	-1.1	-2.7	-2.1	-0.3	-1.8	-1.7	-1.5	-1.5	0.5	0.3
Financial difficulties in last 2 years	0.7	0.9	2.1	-0.7	-0.9	-0.2	-0.8	-0.8	-1.3	0.4	-1.2	-1.2	-0.9	-0.6	-1.4
Mouth/teeth dental problems	1.4	2.1	6.8	0.8	2.6	-0.5	1.7	0.9	-1.1	1.9	1.0	-0.3	1.0	-1.9	-1.9
Heart attack	1.0	1.3	2.4	-1.3	-1.1	-1.0	-0.2	-0.8	-1.3	0.6	-1.1	-1.2	-1.3	-1.5	-1.5
Allergy	1.2	2.7	9.4	1.1	-1.3	1.1	-0.6	0.4	2.1	-1.9	0.1	1.9	0.1	2.5	3.1
Pain all over the body in last month	0.2	0.2	0.4	-0.4	-0.7	0.3	-0.1	0.0	0.2	-0.6	-0.0	-0.5	-0.6	0.1	-0.6
Diabetes (self-reported)	1.0	1.5	2.9	1.7	0.3	1.0	1.2	1.4	1.3	-0.1	1.6	1.5	1.6	0.8	1.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.6	0.4	1.9	0.0	1.7	0.8	-1.2	0.9	0.9	-0.4	0.4	-1.4	-1.9
Medication: Ramipril	0.9	1.2	5.1	-0.9	-2.2	-0.1	-1.5	-1.1	0.2	-1.1	-1.0	-0.7	-1.1	0.8	0.3
Medication: Simvastatin	1.1	1.6	7.3	0.0	0.5	2.1	-0.2	0.2	0.8	-2.7	-0.2	-0.2	-0.9	2.2	-0.3
Fluid intelligence score	1.1	2.2	5.3	1.9	2.2	2.3	2.0	1.9	0.4	-0.5	1.1	1.6	0.3	0.9	0.1
Illnesses of siblings	0.4	0.6	2.0	-0.5	-0.7	0.3	-1.0	0.1	1.3	-0.7	-0.4	0.8	-0.2	0.9	1.4
Neuroticism score	1.8	3.7	7.4	-2.7	-0.4	-0.9	-1.8	-2.1	-2.1	-0.2	-2.5	-2.5	-2.3	-1.0	-2.3
Weight	0.8	4.1	8.1	-1.9	-0.4	-2.1	-1.7	-2.4	-2.8	1.3	-2.6	-2.3	-1.5	-2.1	-1.9
Impedance of arm (right)	0.7	3.4	11.6	0.1	0.4	-1.9	1.5	0.6	-1.7	3.0	0.6	-1.2	0.1	-3.4	-3.1
Arm fat percentage (right)	0.3	1.2	5.9	0.4	0.2	0.5	1.1	0.4	-1.8	0.7	-0.5	-0.6	-0.6	-1.3	-2.4
Trunk fat-free mass	0.9	5.2	12.0	-3.0	-0.6	-2.5	-3.3	-3.5	-1.9	-0.0	-3.4	-2.2	-1.9	-0.6	0.1
Hip circumference	1.6	7.0	9.8	-2.7	-1.3	-3.1	-2.3	-2.9	-3.1	1.8	-3.1	-3.1	-2.1	-3.0	-2.5
Time employed in main current job	0.6	0.7	1.9	0.5	0.3	0.9	-0.0	0.4	1.2	-0.8	0.4	1.1	0.4	1.3	1.4
Alcohol intake versus 10 years previously	0.3	0.4	1.1	-0.1	-0.1	0.5	-0.7	-0.2	0.4	-1.0	-0.8	0.6	-0.6	1.0	1.0
Father’s age at death	0.8	1.0	3.2	-0.5	-0.7	-1.1	0.2	-0.5	-1.8	1.7	-0.4	-0.6	-0.0	-1.8	-0.7
Worrier / anxious feelings	0.4	0.7	3.2	-1.1	-1.8	-0.3	-1.1	-0.1	0.3	-0.4	-0.8	-0.3	-1.2	-0.4	-0.5
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.3	6.8	-2.5	-0.8	-1.7	-1.5	-1.9	-2.6	1.3	-2.4	-2.3	-2.1	-2.4	-2.5
Falls in the last year	0.2	0.2	1.2	0.7	1.1	0.6	0.5	0.2	-0.2	-0.2	0.1	0.3	-0.0	0.3	0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.6	-0.3	0.5	0.8	0.7	-0.2	-0.5	-0.4	0.2	-0.3	0.0	0.5	-0.1
Number of live births	0.8	1.2	4.5	0.3	-0.3	-1.3	-0.0	0.9	1.0	2.1	0.6	0.7	0.8	-2.0	-0.0
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	4.0	-1.4	2.0	-1.6	-0.9	-1.5	-1.7	1.3	-1.6	-1.6	-0.8	-1.4	-1.2
Pulse rate	0.2	0.3	0.7	0.8	-0.7	-0.5	0.4	-0.0	-0.4	0.7	0.1	0.6	0.8	-0.3	0.8
Happiness	0.1	0.2	0.5	-0.6	-0.7	-0.1	-0.4	-0.1	0.6	-0.1	0.0	0.2	-0.0	0.3	0.6
Noisy workplace	1.2	1.5	4.0	0.5	-1.6	0.8	-0.9	0.1	1.7	-1.3	0.4	1.0	0.9	1.9	2.0
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.8	0.8	1.7	1.1	1.5	1.4	0.4	0.3	0.9	1.4	0.8	0.2	0.3
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	6.2	-0.8	-1.1	1.0	-0.9	-1.2	-0.3	-2.5	-1.1	-1.0	-1.2	1.8	0.1
Mouth/teeth dental problems: Dentures	1.2	2.0	5.6	-0.5	-2.1	0.6	-1.6	-0.6	1.2	-2.4	-0.8	0.6	-1.0	2.0	1.9
Asthma	0.7	1.5	8.4	-0.3	0.7	0.0	0.9	0.6	-1.1	1.3	0.2	-0.9	-0.1	-1.9	-2.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.4	-0.4	-1.2	0.3	-0.3	0.0	0.6	-1.0	0.4	0.1	0.2	0.8	0.5
Medication: Cholesterol lowering	0.6	0.9	3.5	-0.4	-0.0	1.6	-0.1	0.5	0.9	-1.9	-0.2	0.0	-1.2	1.3	-0.4
Depression (self-reported)	0.5	0.6	1.5	-0.4	0.8	-0.7	-0.4	-0.2	-0.9	1.2	-0.7	-0.6	-0.3	-1.1	-1.1
Medication: Lansoprazole	1.2	1.3	5.1	1.2	0.8	1.8	2.3	1.0	-1.0	-0.7	0.9	0.0	0.0	0.5	-1.5
Prospective memory result	2.6	3.2	8.0	-2.3	-1.9	-1.9	-2.8	-2.6	-0.6	-0.5	-2.0	-1.8	-1.6	0.0	0.6
Lung cancer (father)	0.6	0.7	2.0	-0.5	-1.2	-0.8	-0.2	-0.2	-0.4	1.2	0.2	-0.8	0.4	-1.4	-1.1
Illnesses of mother	0.7	0.9	2.2	-1.1	-0.2	-1.5	-1.1	-1.2	-0.6	1.1	-1.2	-0.4	-0.5	-0.8	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	5.7	-1.0	2.4	-1.0	-0.2	-0.8	-1.6	1.1	-1.1	-1.2	-0.8	-1.4	-1.5
Pulse wave Arterial Stiffness index	0.7	0.9	3.0	-0.9	-0.8	-1.1	-1.7	-1.0	-0.1	0.4	-1.1	-1.2	-0.7	-0.5	-0.6
Impedance of arm (left)	0.7	3.1	10.0	0.6	0.5	-1.7	1.7	0.7	-1.5	2.8	0.9	-1.0	0.5	-3.2	-2.7
Arm fat mass (right)	0.4	1.8	5.9	-0.5	0.3	-0.4	0.0	-0.8	-2.4	0.8	-1.5	-1.4	-1.2	-1.6	-2.4
Trunk predicted mass	0.9	5.0	11.9	-2.9	-0.5	-2.4	-3.2	-3.5	-1.9	-0.1	-3.3	-2.2	-1.9	-0.5	0.2
Standing height	1.6	15.7	45.0	-4.0	-1.1	-6.7	-4.0	-4.7	-3.6	3.8	-4.0	-4.0	-2.0	-4.6	-1.7
Length of working week for main job	0.2	0.2	0.4	0.6	0.1	0.6	0.2	0.0	0.2	-0.4	0.6	0.1	0.7	0.5	0.3
Exposure to tobacco smoke at home	1.0	1.1	3.1	1.3	1.6	-0.6	0.6	0.6	0.1	1.8	0.8	1.0	1.2	-0.6	1.0
Breastfed as a baby	0.5	0.6	2.8	0.2	-1.7	-1.2	-0.8	-0.4	0.3	0.8	-0.2	0.2	0.1	-0.4	0.9
Tense / ‘highly strung’	2.8	4.7	6.8	-2.6	-1.6	-2.5	-1.7	-2.1	-2.2	1.5	-2.4	-2.6	-2.0	-2.2	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.9	-0.6	-0.4	0.0	0.0	-0.3	-1.4	0.3	-0.9	-1.2	-1.0	-0.6	-2.0
Hair/balding pattern: Pattern 4	1.4	3.4	12.9	0.1	0.6	3.6	1.4	0.9	1.0	-3.1	0.5	1.0	-0.7	3.4	0.9
Birth weight of first child	0.6	1.2	6.5	0.2	2.5	0.9	1.5	0.8	-0.7	0.6	0.3	-0.1	-0.3	-0.7	-1.5
Peak expiratory flow (PEF)	0.2	0.4	1.0	-0.6	1.0	-0.7	-0.3	-0.9	-0.8	0.4	-0.8	-0.7	-0.1	-0.3	-0.3
Pulse wave reflection index	0.4	0.5	1.6	-0.3	1.2	0.7	-0.5	-0.2	-0.1	-1.0	-0.3	-0.9	-0.6	0.5	-1.2
Ever highly irritable/argumentative for 2 days	0.8	0.9	3.5	0.9	0.4	1.9	1.4	0.8	-0.3	-1.0	0.3	1.1	0.0	1.2	0.2
Loud music exposure frequency	1.7	1.9	8.4	0.9	1.6	2.9	1.7	1.0	-0.3	-1.5	0.8	0.5	0.4	1.7	-0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.6	0.4	1.2	0.5	1.6	1.0	-0.4	1.0	0.7	0.5	0.4	-1.1	-1.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.8	0.1	-0.7	-0.3	-0.1	0.4	0.7	0.9	0.3	0.4	0.3	-0.5	0.3
Blood clot in the leg (DVT)	0.7	0.9	3.0	-1.3	-1.7	0.4	-1.4	-0.4	0.4	-0.8	-1.3	0.4	-0.9	0.6	0.6
Medication: Paracetamol	0.1	0.2	0.4	0.7	0.3	0.6	0.4	0.7	0.2	0.3	0.3	0.5	0.0	0.3	-0.1
Headache pain in last month	0.1	0.2	0.7	0.2	0.3	0.7	0.1	0.8	0.2	-0.1	0.0	0.8	-0.1	0.1	0.0
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.9	0.6	0.6	-1.0	0.6	0.3	-0.2	2.0	0.8	0.8	1.6	-1.2	0.7
Glaucoma (self-reported)	0.3	0.3	0.9	-0.9	0.2	0.1	-0.4	0.1	0.1	-0.4	-0.6	-0.3	-1.0	-0.5	-0.9
Gout (self-reported)	1.2	1.6	4.8	-0.2	0.3	-2.0	-0.0	-0.8	-1.7	2.2	-0.7	-1.0	-0.6	-2.0	-1.2
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	3.5	1.2	1.8	0.8	1.8	1.9	0.8	0.5	1.7	1.6	1.6	-0.5	0.1
Medication: Amlodipine	0.3	0.4	1.7	0.6	0.5	0.3	1.3	0.2	-0.8	-0.1	0.6	-0.4	0.1	-0.1	-1.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.5	1.2	-0.3	0.6	0.6	0.5	0.3	0.0	0.9	0.4	1.0	0.5	0.2
Birth weight	0.1	0.2	1.0	0.4	1.0	0.3	0.4	0.1	0.1	-0.1	0.4	-0.0	0.5	0.4	0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.8	0.5	-0.7	0.3	0.1	0.1	0.1	-0.7	0.2	0.4	-0.3	0.7	0.9
High blood pressure (siblings)	0.7	0.9	3.0	0.5	1.0	-0.3	1.3	-0.1	-1.7	0.7	0.4	-0.9	0.1	-1.0	-1.7
Forced vital capacity (FVC), Best measure	0.5	1.8	4.2	-1.1	2.0	-1.6	-0.5	-1.2	-1.5	1.3	-1.1	-1.4	-0.7	-1.5	-1.2
Body fat percentage	0.4	1.7	5.6	0.2	-0.7	-0.9	0.4	0.0	-1.9	1.7	-0.7	-0.8	-0.5	-2.3	-2.4
Leg fat percentage (right)	0.3	1.0	3.8	0.2	-0.3	-0.4	0.4	0.1	-1.6	1.2	-0.5	-0.6	-0.3	-1.6	-2.0
Arm fat-free mass (right)	0.7	3.7	8.9	-2.2	-0.9	-2.1	-3.0	-3.0	-1.6	0.0	-3.0	-1.6	-1.5	-0.4	0.5
Exposure to tobacco smoke outside home	0.8	1.0	2.8	-0.5	0.2	-1.0	-0.0	-0.7	-1.7	1.5	-0.4	-1.1	-0.1	-1.5	-1.3
Comparative body size at age 10	0.3	0.8	3.7	0.5	1.3	1.9	1.0	0.6	-0.5	-0.4	0.2	-0.1	0.3	0.5	-1.2
Number of full brothers	1.4	1.7	3.5	1.7	0.1	1.3	1.4	1.9	1.5	0.2	1.4	1.8	1.7	0.5	0.6
Worry too long after embarrassment	1.1	1.8	4.6	-1.7	1.1	1.3	-0.8	-0.7	-0.3	-2.1	-1.2	-1.5	-1.9	1.0	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	3.3	-0.5	0.8	0.3	0.5	0.0	-0.9	0.1	-0.4	-0.8	-0.8	-0.5	-1.8
Wheeze or whistling in the chest in last year	0.6	1.0	5.3	-0.3	0.9	1.2	1.2	1.0	-0.5	-0.1	0.2	-0.5	-1.0	-0.6	-2.3
Number of children fathered	1.5	1.7	5.6	-1.1	-2.4	-1.7	-0.9	-1.1	-1.1	1.3	-0.7	-1.3	-0.3	-1.5	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	5.4	-0.3	-0.2	-2.3	-0.1	-1.2	-1.8	2.2	-0.4	-1.4	0.3	-2.1	-1.0
Age at first live birth	0.6	1.1	2.7	-1.1	-1.0	-1.6	-1.0	-1.3	-0.9	1.3	-1.0	-0.8	-0.3	-0.9	0.3
Pulse wave peak to peak time	0.4	0.4	2.0	0.5	0.7	0.6	1.4	0.6	-0.2	-0.1	0.7	0.8	0.4	0.1	0.4
Health satisfaction	0.7	0.9	3.2	-0.1	1.1	1.8	0.7	0.7	0.5	-1.6	0.4	-0.1	-0.6	1.0	-0.8
Shortness of breath walking on level ground	0.1	0.1	0.5	-0.1	-0.2	0.0	0.0	0.0	-0.4	0.3	-0.0	-0.2	0.0	-0.6	-0.7
Qualifications: College or University degree	0.3	1.1	2.4	1.1	1.1	1.3	0.9	0.8	0.9	-1.0	0.9	1.0	0.9	1.6	1.0
Eye problems/disorders: None of the above	0.3	0.4	2.1	0.0	-1.4	-0.2	-0.3	-0.7	-0.7	-0.4	-0.6	-0.4	-0.6	0.4	0.0
Mouth/teeth dental problems: Loose teeth	3.4	4.1	8.5	2.5	0.4	1.1	2.4	2.6	1.8	1.0	2.9	2.5	2.9	-0.0	1.2
Emphysema/chronic bronchitis	1.2	1.4	4.6	-1.6	-0.6	-0.2	-1.5	-1.2	-0.4	-0.7	-1.8	-1.0	-2.1	0.3	-0.4
Medication for pain relief, constipation, heartburn	1.1	1.9	4.8	0.4	1.9	-1.4	0.9	-0.4	-1.9	2.1	0.1	-0.8	0.7	-2.2	-1.4
Neck or shoulder pain in last month	0.1	0.2	0.7	0.4	-0.2	0.4	-0.4	-0.1	0.2	-0.7	-0.2	0.4	-0.0	0.8	0.6
Medication: Blood pressure	0.2	0.3	1.4	0.5	-0.2	0.1	0.6	0.1	-0.6	-0.2	-0.0	-0.7	-0.8	-0.2	-1.2
Angina (self-reported)	1.0	1.3	5.7	-0.6	-1.0	0.8	-1.3	-0.5	0.7	-2.4	-1.1	-0.2	-1.7	1.3	0.4
Migraine (self-reported)	0.3	0.4	1.5	-0.2	0.2	-0.1	-0.3	-0.4	-1.1	0.0	-0.8	-0.6	-1.2	-0.1	-0.7
Medication: Ibuprofen	0.2	0.2	0.6	0.0	-0.4	0.4	0.4	0.3	0.4	-0.7	0.8	0.2	0.5	0.7	0.3
Medication: Allopurinol	0.6	0.8	3.7	0.1	-0.8	-1.9	-0.6	-0.8	-0.8	1.5	-0.4	-0.3	0.1	-1.2	0.3
Medication: Omeprazole	0.1	0.2	0.7	-0.5	-0.1	0.3	-0.5	0.3	0.5	-0.2	-0.5	0.2	-0.8	0.1	-0.0
Medication: Seretide 50 evohaler	1.0	1.2	2.1	-1.2	0.4	-0.3	-1.0	-1.3	-1.2	-1.0	-1.3	-1.5	-1.3	-0.3	-1.2
Mean time to correctly identify matches	0.8	1.5	3.3	-1.5	-1.4	-1.8	-1.8	-0.8	0.0	0.9	-1.0	-1.0	-0.8	-1.7	-0.7
Heart disease (mother)	0.6	0.7	2.6	-0.6	-0.5	0.9	-0.6	-0.6	0.1	-1.6	-0.5	-0.3	-0.9	1.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.1	3.7	7.1	2.5	2.5	1.6	2.5	2.3	0.7	1.1	2.5	1.6	2.7	-0.0	-0.2
Whole body fat mass	0.4	1.7	4.5	-0.2	-0.5	-1.1	-0.2	-0.6	-2.1	1.5	-1.2	-1.1	-0.7	-2.1	-2.0
Leg fat mass (right)	0.5	1.8	5.6	-0.5	-0.4	-1.0	-0.4	-1.0	-2.4	1.2	-1.5	-1.3	-0.9	-1.7	-2.0
Arm predicted mass (right)	0.7	3.4	8.3	-2.1	-0.9	-2.0	-2.8	-2.9	-1.6	0.1	-2.8	-1.6	-1.3	-0.4	0.4
Pulse rate, automated reading	0.7	2.3	7.8	2.0	1.1	-0.7	0.7	0.9	0.7	1.7	1.4	1.9	2.8	-0.6	1.9
Alcohol intake frequency.	0.8	1.9	5.0	-2.2	-1.1	-0.9	-1.6	-1.6	-1.2	-0.1	-2.2	-0.9	-2.0	-0.5	-0.2
Comparative height size at age 10	0.4	2.3	7.2	-1.5	-0.1	-2.7	-2.0	-2.0	-1.3	0.8	-1.7	-1.4	-0.8	-1.5	-0.2
Number of full sisters	0.6	0.7	2.0	-0.3	1.4	-0.3	0.4	-0.5	-1.4	0.8	-0.7	-0.7	-0.9	-0.6	-1.0
Suffer from ‘nerves’	2.1	3.2	6.2	-2.5	-0.5	-0.6	-1.2	-2.0	-2.2	-0.4	-2.5	-2.3	-2.5	-0.6	-2.0
Overall health rating	0.4	0.8	1.9	-1.0	-0.6	-0.2	-0.5	-0.5	-1.1	-0.1	-1.1	-0.8	-1.4	-0.8	-1.3
Chest pain or discomfort	0.4	0.6	2.2	-1.4	-0.3	0.0	-0.5	-0.6	0.0	-1.0	-0.9	-0.7	-1.5	0.1	-0.5
Had major operations	0.5	0.5	0.9	0.9	-0.9	0.9	0.5	0.7	0.6	-0.7	0.6	0.8	0.6	0.8	0.5
Age at last live birth	0.8	1.2	3.5	-1.0	-0.6	-1.8	-1.0	-0.8	-0.7	1.9	-1.2	-0.5	-0.4	-1.6	-0.2
Family relationship satisfaction	1.0	1.3	3.6	1.3	1.9	1.1	1.5	1.2	0.7	-0.5	1.5	0.7	0.8	0.8	0.3
Leg pain on walking	1.4	1.8	6.3	-2.5	-0.5	-0.9	-1.8	-1.5	-0.7	0.2	-1.9	-1.3	-1.4	-0.8	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	7.2	-0.3	2.7	-0.5	1.0	0.5	-1.1	2.1	0.3	-0.3	0.5	-1.9	-1.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.5	-0.6	-1.6	-0.9	-0.6	-1.0	-0.8	-0.2	-0.7	-1.0	-0.7	-0.5	-0.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.0	3.6	-0.0	1.9	-0.9	0.7	0.8	0.6	1.4	1.3	0.3	1.1	-1.3	-0.1
Medication: Aspirin	0.8	1.1	3.6	-0.2	-1.3	1.3	-0.1	-0.0	0.6	-1.9	-0.3	0.6	-0.8	1.9	1.0
Supplements: Vitamin C	0.3	0.4	1.6	-0.4	-0.8	0.1	-0.0	-0.6	-1.3	-0.4	-0.7	-0.4	-0.9	-0.0	-0.3
Knee pain experienced in last month	1.1	1.6	3.6	-1.5	-0.6	-1.6	-1.6	-1.5	-1.3	0.8	-1.9	-0.9	-1.3	-1.0	-0.0
Hypertension (Self-reported)	0.5	1.3	4.4	0.2	1.3	1.0	0.6	-0.2	-1.4	-1.2	-0.6	-1.2	-1.7	0.6	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.6	-0.7	-1.0	0.8	-0.8	-0.3	0.2	-2.0	-1.2	-0.3	-2.1	1.3	-0.0
Illnesses of father: Heart disease	0.9	1.2	3.9	-0.6	1.0	0.9	0.1	-1.1	-1.0	-2.0	-0.8	-1.1	-1.5	1.5	-0.5
Illnesses of siblings: Diabetes	0.0	0.1	0.3	-0.1	0.1	0.2	-0.0	-0.2	-0.1	-0.3	-0.1	0.0	-0.2	0.5	0.3
Smoking status: Previous	0.2	0.3	1.8	0.5	-1.4	-0.6	-0.3	-0.5	-0.1	-0.3	-0.1	-0.1	-0.0	0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.6	-1.6	-0.7	-1.5	-1.2	-1.3	-0.8	0.2	-1.6	-0.8	-1.3	-0.6	-0.2
Whole body fat-free mass	0.8	4.5	10.5	-2.6	-0.4	-2.1	-2.8	-3.2	-2.1	0.1	-3.2	-2.2	-1.9	-0.7	-0.3
Leg fat-free mass (right)	0.6	3.2	7.8	-2.1	0.3	-1.3	-1.9	-2.6	-2.3	0.2	-2.8	-2.1	-1.7	-0.7	-1.0
Arm fat percentage (left)	0.2	0.9	4.1	0.8	0.2	0.7	1.2	0.6	-1.5	0.6	-0.2	-0.3	-0.4	-1.0	-2.0
Average weekly red wine intake	0.7	1.1	5.3	-0.3	0.6	0.2	1.2	0.3	-1.3	1.0	0.4	-1.0	-0.1	-1.3	-2.3
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	0.5	0.1	-0.5	0.5	-0.0	-0.8	0.5	-0.1	-0.2	-0.2	-0.8	-0.5
Mood swings	3.7	6.8	13.6	-3.7	-0.5	-1.7	-2.3	-2.8	-2.9	0.4	-3.4	-3.2	-3.0	-1.9	-2.9
Loneliness, isolation	2.0	2.8	9.1	-1.8	0.7	-0.6	-0.2	-1.1	-2.4	0.8	-1.5	-2.2	-1.7	-1.8	-3.0
Long-standing illness, disability or infirmity	1.3	1.9	4.0	-1.6	-1.9	-0.1	-2.0	-1.5	-0.5	-1.4	-1.7	-1.4	-1.8	0.5	-0.5
Ever had bowel cancer screening	0.6	0.8	2.9	-0.4	-1.7	-1.1	-0.9	-0.8	-0.5	0.6	-0.7	-0.8	-0.6	-1.0	-0.5
Diabetes diagnosed by doctor	1.1	1.8	3.6	1.8	0.8	1.2	1.5	1.7	1.3	-0.1	1.9	1.4	1.6	0.8	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.5	1.4	0.8	1.3	0.7	0.9	1.1	-1.2	0.9	1.3	0.4	1.6	1.4
Friendships satisfaction	1.3	1.6	2.8	1.6	1.7	1.6	1.6	1.4	0.8	-0.2	1.5	1.3	1.0	1.1	0.7
Qualifications: nursing, teaching	1.2	1.9	6.1	1.6	1.1	1.2	2.5	1.8	0.4	1.0	2.0	1.1	1.6	0.1	-0.1
Commuting to job workplace: Walk	0.1	0.1	0.3	0.3	0.5	-0.0	0.2	-0.4	-0.5	-0.2	-0.1	-0.3	0.2	0.2	-0.1
Eye problems/disorders: Cataract	0.6	0.6	5.3	0.2	2.3	0.8	0.4	0.7	0.4	0.2	0.4	0.6	0.5	0.0	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	7.1	-1.6	-1.6	1.0	-2.1	-1.8	0.1	-2.7	-1.7	-0.6	-1.4	2.7	1.5
Medication for cholesterol	0.5	0.7	2.3	-0.8	-0.7	-1.5	-0.9	-0.4	0.3	1.5	-0.2	-0.0	0.5	-1.3	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	5.2	-0.9	-1.6	1.1	0.2	-0.3	-1.2	-1.1	-1.1	-0.9	-2.3	0.5	-1.3
Back pain experienced in last month	0.5	0.7	1.8	-1.2	-0.5	-0.2	-1.3	-0.6	0.4	-0.9	-0.8	0.2	-0.8	0.6	1.2
Mineral and other dietary supplements	0.5	0.6	1.4	0.4	0.6	1.2	0.9	1.2	1.0	-0.6	0.9	0.8	0.6	0.4	-0.1
Breast cancer (self-reported)	1.4	1.7	4.8	-0.5	1.7	-0.9	0.4	0.0	-1.4	2.1	-0.6	-0.8	-0.4	-2.2	-2.0
Asthma (self-reported)	0.7	1.3	6.4	-0.0	0.9	-0.0	1.0	0.8	-0.8	1.4	0.5	-0.6	0.2	-1.9	-2.5
Osteoporosis (self-reported)	1.6	2.0	6.9	2.0	2.6	1.6	0.9	1.1	1.0	-1.1	1.2	1.2	0.9	1.4	0.8
Osteoarthritis (self-reported)	0.7	0.9	2.8	-1.7	-0.7	-0.6	-1.3	-0.9	-0.3	0.4	-1.3	-0.8	-1.1	-0.6	-0.4
Medication: Aspirin	0.6	0.8	2.9	-0.2	-1.1	1.3	0.1	0.2	0.6	-1.7	-0.2	0.5	-0.8	1.5	0.5
Medication: Gliclazide	0.5	0.5	1.8	0.6	0.7	0.8	0.1	0.0	0.5	-1.0	0.7	0.2	0.9	1.4	0.8
Illnesses of father: None of the above (group 1)	0.9	1.1	2.5	0.9	-1.6	-0.8	-0.1	0.7	1.3	1.1	0.9	1.2	1.2	-0.4	1.4
Smoking status: Current	0.1	0.2	0.7	0.3	0.7	0.6	0.1	0.3	0.3	-0.4	0.1	0.7	-0.1	0.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	7.2	0.5	2.7	1.3	1.3	0.9	0.1	0.3	0.7	0.5	0.7	0.3	-0.5
Whole body water mass	0.7	4.1	9.9	-2.5	-0.4	-2.0	-2.8	-3.1	-2.0	0.1	-3.1	-2.0	-1.8	-0.6	-0.1
Leg predicted mass (right)	0.7	3.5	8.3	-2.2	0.2	-1.4	-2.0	-2.7	-2.4	0.2	-2.9	-2.2	-1.8	-0.8	-1.1
Arm fat mass (left)	0.3	1.2	4.4	-0.3	0.1	-0.3	0.1	-0.6	-2.1	0.8	-1.2	-1.0	-0.8	-1.4	-1.9
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	-0.3	-0.0	0.9	0.1	0.3	-0.0	-0.9	-0.5	-0.0	-1.1	0.5	-0.7
Average weekly champagne plus white wine intake	0.2	0.3	1.0	0.4	0.2	0.5	0.1	0.8	0.8	0.1	0.2	1.0	0.0	0.0	0.6
Miserableness	2.4	4.1	9.9	-3.1	-0.4	-0.9	-2.3	-2.2	-2.1	-0.0	-2.9	-2.4	-2.3	-0.9	-1.9
Guilty feelings	0.9	1.4	2.8	1.4	1.4	1.7	1.5	1.3	0.6	-0.6	1.4	1.0	0.9	1.1	0.1
Wears glasses or contact lenses	2.1	2.4	6.2	-1.8	-1.6	0.2	-1.6	-1.6	-0.4	-2.2	-1.6	-1.6	-2.5	1.3	-0.5
Ever taken oral contraceptive pill	0.4	0.4	1.0	-0.9	-0.6	-0.4	-0.6	-0.9	-0.8	0.1	-1.0	-0.4	-0.9	0.1	0.2
Hearing aid user	0.4	0.4	1.7	0.0	0.1	0.5	0.7	-0.2	-1.3	-0.2	-0.4	-0.6	-0.9	0.1	-1.0
Mother’s age at death	0.9	1.2	5.0	-0.6	-0.5	-2.2	-1.3	-1.1	-0.2	1.7	-0.5	-0.3	0.8	-1.1	0.9
Financial situation satisfaction	0.2	0.3	1.0	-0.1	-0.7	1.0	0.2	0.4	0.4	-0.9	0.1	-0.2	-0.2	0.6	-0.7
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	0.0	0.5	-0.1	-0.6	0.2	0.2	-0.1	0.0	0.0	0.3	-0.1	-0.1
Commuting to job workplace: Public transport	0.7	0.8	2.3	-0.1	1.3	1.5	0.2	0.1	-0.2	-1.2	-0.7	0.7	-1.0	1.4	0.5
Eye problems/disorders: Glaucoma	1.0	1.1	2.3	-1.5	0.3	-0.9	-0.7	-0.7	-0.8	0.3	-1.3	-1.1	-1.5	-1.3	-1.4
Medication: Blood pressure	0.6	1.2	4.0	0.1	1.0	1.3	0.1	-0.3	-0.9	-2.0	-0.6	-0.8	-1.5	1.5	-1.1
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.1	-0.5	0.4	0.4	-0.4	-0.5	-0.5	-0.7	-1.0	0.1	-1.0	0.4	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	1.0	-0.2	-1.0	0.0	-0.4	-0.4	-0.3	-0.4	-0.4	-0.2	-0.4	0.4	0.1
High cholesterol (Self-reported)	1.4	2.5	7.4	1.7	1.2	2.7	1.1	1.5	1.3	-2.4	1.0	1.3	0.2	2.3	0.4
Medication: Bendroflumethiazide	1.0	1.5	3.8	1.6	1.3	1.8	1.9	1.0	-0.4	-1.5	1.1	0.2	0.0	1.1	-0.7
Medication: Paracetamol	0.2	0.4	1.7	0.6	1.3	0.9	0.6	0.7	0.2	-0.2	0.4	0.3	0.1	0.5	-0.5
Medication: Lisinopril	0.4	0.5	2.0	0.6	0.4	1.4	0.6	0.8	0.4	-1.0	0.2	0.0	-0.8	0.8	-0.7
Medication: Atorvastatin	0.8	1.0	2.4	1.0	1.6	1.2	1.2	1.1	0.8	-0.9	0.8	0.9	-0.1	1.0	0.5
Illnesses of father: High blood pressure	3.2	4.0	12.1	-1.9	1.7	0.3	-0.4	-1.5	-2.8	-0.8	-2.1	-2.8	-2.5	-0.5	-3.5
Alcohol drinker status: Never	2.0	2.4	5.3	-2.0	1.2	0.7	-1.4	-1.5	-0.5	-2.3	-1.8	-1.5	-2.2	1.3	-0.8
Ever smoked	0.3	0.5	1.2	0.0	-1.1	-0.9	-0.7	-1.0	-0.4	-0.4	-0.6	-0.6	-0.8	0.4	0.5
Basal metabolic rate	0.8	4.4	9.8	-2.5	-0.3	-2.2	-2.5	-3.0	-2.5	0.6	-3.1	-2.3	-1.8	-1.2	-0.9
Leg fat percentage (left)	0.4	1.5	4.7	-0.3	-0.7	-1.1	-0.1	-0.3	-1.8	1.7	-1.0	-0.9	-0.5	-2.2	-2.0
Arm fat-free mass (left)	0.9	4.7	10.2	-2.7	-0.8	-2.6	-3.0	-3.1	-2.0	0.6	-3.2	-2.1	-1.7	-1.2	-0.3
Number of operations (self-reported)	0.1	0.2	1.2	0.3	-1.1	0.0	-0.2	0.1	0.1	-0.2	-0.5	0.5	-0.2	0.1	0.4
Average weekly beer plus cider intake	0.4	0.6	2.3	-0.0	-1.0	-1.4	-0.3	-0.3	-0.4	1.5	-0.2	0.3	0.4	-0.9	0.6
Irritability	0.6	1.1	2.1	-1.4	-0.7	-1.2	-1.2	-1.1	-1.1	0.4	-1.4	-0.9	-1.3	-0.8	-0.5
Risk taking	0.2	0.3	2.1	0.3	-1.4	0.4	0.5	0.4	0.1	-0.4	0.0	0.0	-0.8	0.2	-0.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	4.1	0.3	0.2	2.0	1.3	0.7	0.2	-1.2	0.7	0.4	0.0	1.4	0.0
Fractured/broken bones in last 5 years	0.7	1.0	2.8	-0.2	-1.2	0.8	-0.6	-0.0	0.9	-1.5	-0.1	0.8	-0.3	1.7	1.6
Age started oral contraceptive pill	0.7	0.8	3.3	0.7	0.2	-1.2	0.5	0.5	-0.2	1.8	0.7	0.6	0.9	-1.5	0.4
Diastolic blood pressure, automated reading	1.2	3.7	7.8	-1.6	1.5	-1.4	-1.0	-1.8	-2.2	0.0	-2.2	-2.7	-2.5	-1.4	-2.8
Ever depressed for a whole week	1.7	2.1	7.4	0.2	1.6	2.7	0.6	0.7	0.7	-2.4	0.3	-0.1	-0.8	2.6	-0.5
Unable to work because of sickness or disability	0.7	0.8	4.1	-0.0	-1.0	-0.0	-1.1	0.5	2.0	-0.6	0.3	0.9	0.4	0.7	1.3
Commuting to job workplace: Cycle	0.2	0.3	1.2	0.0	0.2	-0.9	-0.2	-0.1	-0.2	1.1	-0.0	0.3	0.1	-0.7	0.5
Myopia	0.8	1.2	2.6	-0.3	1.0	1.6	0.5	0.1	-0.4	-1.6	-0.5	-0.9	-1.6	1.0	-1.6
Vascular/heart problems diagnosed by doctor	0.8	2.1	7.0	0.8	-0.1	-1.1	0.6	0.9	1.1	2.1	1.7	1.5	2.7	-1.2	1.6
Cholesterol lowering medication	1.4	2.1	7.7	1.3	2.8	2.3	1.4	0.8	0.1	-1.9	0.7	0.4	-0.1	1.9	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.5	-0.5	-0.3	0.6	-0.2	0.4	0.5	-0.1	-0.3	0.1	-0.7	0.1	-0.4
Pain experienced in last month	0.6	1.0	2.9	1.4	-0.1	0.2	1.5	1.1	0.7	0.8	1.7	0.3	1.6	-0.2	-0.2
Supplements: Calcium	0.4	0.5	1.6	0.3	1.3	-1.0	0.2	0.1	-0.6	1.1	-0.0	-0.1	-0.1	-1.1	-0.3
Basal cell carcinoma (self-reported)	1.1	1.3	3.3	1.0	0.8	0.2	1.4	1.2	0.2	1.5	1.5	0.5	1.8	-1.1	-0.8
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.0	-1.4	-1.2	-1.0	-0.4	-1.0	-1.3	0.5	-1.2	-1.3	-1.4	-1.4	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.6	-1.3	-1.6	0.5	-1.3	-0.3	0.6	-0.9	-1.2	0.3	-0.9	0.7	0.6
Heart disease (siblings)	0.9	1.1	2.3	1.5	0.6	0.7	1.5	1.3	0.4	0.5	1.5	1.1	1.5	-0.0	0.2
Alcohol drinker status: Previous	3.2	3.6	5.8	-1.7	-1.4	-2.3	-0.8	-1.7	-2.4	1.7	-1.7	-2.1	-1.9	-2.4	-2.0
Pack years of smoking	0.3	0.5	1.4	0.7	-0.2	-0.9	-0.6	0.2	1.0	0.3	0.4	0.7	0.8	-0.3	1.2
Impedance of whole body	0.9	4.6	17.4	-0.1	-0.7	-3.3	0.6	0.2	-1.5	3.9	0.4	-1.2	0.3	-4.2	-2.4
Leg fat mass (left)	0.5	2.1	5.5	-0.8	-0.6	-1.3	-0.7	-1.2	-2.3	1.3	-1.7	-1.4	-1.0	-1.9	-1.9
Arm predicted mass (left)	0.8	4.1	9.0	-2.5	-0.7	-2.4	-2.8	-3.0	-1.9	0.5	-3.0	-1.9	-1.5	-1.0	-0.0