TWAS hub - DPY19L2P4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0560	0.0260	0.00290	0.016	0.013	0.008	0.015	0.006	0.0044	0.0093	0.0310	0.0059	0.056
2	TCGA	Prostate Adenocarcinoma	0.0731	0.0351	0.00061	0.025	0.021	0.020	NA	0.022	0.0010	0.0023	0.0029	NA	0.002

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Migraine (self-reported)	4.3	5.4	8.7	3.0	1.4
Lung FEV1/FVC ratio	4.2	21.1	40.3	1.3	6.3
Diastolic blood pressure, automated reading	4.2	13.1	23.7	-1.6	-4.9
Ever had stillbirth, spontaneous miscarriage or termination	4.1	4.4	4.4	-2.1	2.1
Maternal smoking around birth	3.6	5.2	8.7	3.0	1.3
Fasting Glucose	3.5	4.2	7.7	2.8	0.9
Medication for cholesterol	3.4	5.1	10.2	0.2	3.2
Allergy or Eczema	3.3	8.8	10.8	3.3	2.6
Medication: Omeprazole (e.g. Zanprol)	3.3	4.0	6.8	2.6	1.1
Length of working week for main job	3.2	3.6	4.4	2.1	1.6
Mean Putamen Volume	3.0	3.5	4.8	-1.4	2.2
Supplements: Calcium	2.7	3.0	4.9	-1.1	-2.2
Fractured/broken bones in last 5 years	2.6	3.3	4.1	2.0	1.6
Hayfever, allergic rhinitis or eczema	2.5	5.4	6.0	2.5	2.2
Breastfed as a baby	2.4	3.0	5.7	-2.4	0.6
Number of children fathered	2.4	2.7	5.4	0.1	2.3
Medication: Omeprazole	2.4	2.9	5.0	2.2	0.8
Impedance of arm (right)	2.3	10.9	20.7	4.6	1.1
Impedance of arm (left)	2.3	10.8	19.0	4.4	1.6
Arm predicted mass (right)	2.2	11.3	17.2	-4.2	-2.3
Osteoporosis (self-reported)	2.2	2.8	3.6	1.4	-1.9
Mouth/teeth dental problems: Bleeding gums	2.1	2.8	5.4	-0.3	-2.3
Headache pain in last month	2.1	3.7	5.1	2.3	1.5
Arm fat-free mass (right)	2.1	10.6	16.4	-4.0	-2.2
Wears glasses or contact lenses	2.1	2.4	4.8	-2.2	0.1
Medication: Atorvastatin	2.1	2.6	3.3	1.4	1.8
Depressed Affect (Nagel 2018)	2.0	4.1	6.2	2.5	1.4
Age at first live birth	2.0	3.6	5.1	2.3	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.3	7.6	1.0	2.8
Impedance of whole body	2.0	10.0	15.9	4.0	2.0
Major Depression (MDD)	1.9	2.3	4.5	2.1	0.2
Medication: Ramipril	1.9	2.5	2.6	-1.6	-1.6
Depression (self-reported)	1.9	2.3	4.4	2.1	-0.3
Medication: Ventolin 100micrograms inhaler	1.9	2.4	3.5	1.9	1.2
Illnesses of father: High blood pressure	1.9	2.3	3.5	1.9	1.1
Lupus	1.8	2.7	5.0	2.2	0.6
Diabetes (father)	1.8	2.2	3.0	1.2	1.7
Worry too long after embarrassment	1.8	3.0	5.6	2.4	0.6
Arm predicted mass (left)	1.8	9.0	13.2	-3.6	-2.2
Alcohol intake versus 10 years previously	1.7	2.5	5.1	2.2	-0.2
Heart disease (mother)	1.7	2.1	3.4	-0.9	1.8
Ever taken oral contraceptive pill	1.7	1.9	1.9	1.4	1.4
Arm fat-free mass (left)	1.7	8.7	13.9	-3.7	-1.9
Alzheimer’s Disease (in mother)	1.6	1.9	2.3	-1.2	1.5
Frequency of depressed mood in last 2 weeks	1.6	2.2	2.2	1.5	-1.5
Hearing difficulty/problems: Yes	1.6	2.4	4.8	2.2	0.3
Medication: Metformin	1.6	2.3	4.6	-2.1	0.1
Hearing difficulty/problems with background noise	1.6	2.5	4.9	2.2	-0.3
Allergy	1.6	3.7	4.8	-2.2	-1.6
Trunk predicted mass	1.6	9.0	13.1	-3.6	-2.2
Birth weight	1.6	3.4	4.3	-2.1	1.6
Medication: Blood pressure	1.6	2.8	3.1	-1.8	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	3.6	1.9	0.3
Alzheimer’s Disease (in father)	1.5	1.6	1.9	1.4	1.1
Fed-up feelings	1.5	2.8	4.7	2.2	0.9
Trunk fat-free mass	1.5	8.8	12.9	-3.6	-2.1
Loud music exposure frequency	1.5	1.7	2.2	1.1	-1.5
Qualifications: nursing, teaching	1.5	2.3	4.4	-0.6	-2.1
Eye problems/disorders: Cataract	1.5	1.8	3.4	-1.9	0.3
Heart disease (siblings)	1.5	1.9	3.8	1.9	-0.0
Diabetes (mother)	1.4	1.8	3.5	1.9	0.3
Birth weight of first child	1.4	2.6	5.1	-0.3	2.3
Age at last live birth	1.4	2.1	2.7	1.2	1.6
Whole body fat-free mass	1.4	7.8	10.5	-3.2	-2.3
Commuting to job workplace: Walk	1.4	1.5	2.1	-0.9	-1.5
Whole body water mass	1.4	7.8	10.8	-3.3	-2.2
Miserableness	1.4	2.4	4.7	2.2	-0.4
Chronic bronchitis/emphysema (father)	1.3	1.6	2.6	0.7	-1.6
Illnesses of mother	1.3	1.6	2.3	1.0	-1.5
Mother’s age at death	1.3	1.7	3.3	0.2	-1.8
Alcohol drinker status: Never	1.3	1.5	2.2	0.9	1.5
Average weekly beer plus cider intake	1.3	1.9	2.0	1.4	1.4
Reaction Time	1.2	2.4	4.0	-0.9	-2.0
Prostate Cancer	1.2	1.7	3.4	-1.9	0.2
Neuroticism (2016)	1.2	1.7	3.2	1.8	-0.4
Relative age of first facial hair	1.2	2.5	4.9	-0.4	-2.2
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	1.8	-0.9	-1.4
Impedance of leg (left)	1.2	6.0	7.5	2.7	2.1
Mean time to correctly identify matches	1.2	2.2	2.2	-1.5	-1.5
Medication: Bendroflumethiazide	1.2	1.8	3.5	-0.3	-1.9
Neuroticism (Nagel 2018)	1.1	2.5	4.8	2.2	-0.5
Ovarian Cancer	1.1	1.4	2.9	-0.1	-1.7
HDL Cholesterol	1.1	1.9	2.7	-1.6	-1.1
Rheumatoid Arthritis	1.1	1.5	2.5	1.6	0.6
Vitamin and mineral supplements	1.1	1.5	1.8	1.1	1.3
Leg fat-free mass (left)	1.1	5.7	5.9	-2.4	-2.4
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	1.9	-1.4	0.7
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.9	1.4	0.8
Gout (self-reported)	1.1	1.5	1.7	1.1	1.3
Supplements: Vitamin C	1.1	1.3	1.6	-1.0	-1.3
Financial situation satisfaction	1.1	1.4	2.8	0.3	-1.7
Commuting to job workplace: Public transport	1.1	1.3	1.8	-1.3	-0.9
Basal metabolic rate	1.1	6.3	7.6	-2.8	-2.2
Triglycerides	1.0	1.6	3.2	1.8	0.2
Respiratory disease	1.0	2.2	2.7	1.3	1.6
Chronotype (morning person)	1.0	2.4	4.6	0.5	2.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.2	2.3	-1.5	0.2
Impedance of leg (right)	1.0	4.8	6.0	2.4	1.9
Leg predicted mass (left)	1.0	5.3	5.4	-2.3	-2.3
Had menopause	1.0	1.2	2.1	-1.4	-0.6
Financial difficulties in last 2 years	1.0	1.4	2.0	1.4	-0.9
Medication: Cholesterol lowering	1.0	1.5	2.1	1.4	1.0
Exposure to tobacco smoke at home	1.0	1.1	1.7	-0.7	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.5	1.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	1.5	-1.2	0.9
Shortness of breath walking on level ground	1.0	1.2	2.1	-0.5	-1.5
Eye problems/disorders: None of the above	1.0	1.1	1.3	0.9	-1.2
Suffer from ‘nerves’	1.0	1.6	3.1	-0.1	-1.8
Smoking status: Previous	1.0	1.5	2.9	-1.7	-0.1
Leg fat-free mass (right)	1.0	5.3	5.3	-2.3	-2.3
Medication: Blood pressure	1.0	1.9	3.5	-0.6	-1.9
Alcohol drinker status: Previous	1.0	1.1	1.4	-1.2	0.9
Depression (Nagel 2018)	0.9	1.4	2.2	0.8	-1.5
LDL Cholesterol	0.9	1.4	1.8	-1.3	1.0
Type 2 Diabetes (T2D) (2018)	0.9	1.7	2.6	1.6	0.9
Mouth/teeth dental problems	0.9	1.4	2.4	0.7	1.5
Mouth/teeth dental problems: Dentures	0.9	1.5	2.8	0.4	1.7
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.9	-0.3	-1.7
Mood swings	0.9	1.7	2.2	1.5	1.1
Leg predicted mass (right)	0.9	5.1	5.2	-2.2	-2.3
Waist Hip Ratio (WHR)	0.8	3.8	4.1	1.9	-2.0
Qualifications: CSEs or equivalent	0.8	1.0	1.1	1.0	1.1
Serious illness, injury or assault to yourself	0.8	1.0	1.8	1.4	0.3
Nervous feelings	0.8	1.5	1.7	1.3	-1.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.4	0.8	1.2
Neuroticism score	0.8	1.6	3.1	1.8	0.1
Worrier / anxious feelings	0.8	1.5	2.5	1.6	0.7
Hair/balding pattern: Pattern 3	0.8	1.2	2.3	-1.5	0.4
Comparative body size at age 10	0.8	2.2	3.1	1.2	-1.8
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.2	-0.9	-1.1
Friendships satisfaction	0.8	1.0	1.2	1.1	-0.9
Hearing aid user	0.8	0.9	1.1	-0.8	1.1
Schizophrenia (2018)	0.7	1.4	2.2	0.7	-1.5
Alzheimer’s Disease (including proxy)	0.7	1.0	1.7	-0.6	1.3
Crohns Disease (2017)	0.7	1.5	3.0	0.3	1.7
Sensitivity / hurt feelings	0.7	1.2	2.4	1.5	-0.3
Medication for hormone replacement therapy	0.7	0.8	0.8	-0.9	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	2.5	1.6	0.8
Multivitamins +/- minerals	0.7	0.9	0.9	-0.9	-0.9
Asthma	0.7	1.3	2.1	1.4	0.7
Glaucoma (self-reported)	0.7	0.8	1.1	1.0	-0.7
Number of full brothers	0.7	0.9	0.9	0.9	1.0
Health satisfaction	0.7	0.9	1.6	-0.5	-1.3
Chest pain or discomfort	0.7	1.0	1.9	-1.4	0.2
Breast cancer (self-reported)	0.7	0.9	1.2	1.1	0.7
Illnesses of father: None of the above (group 1)	0.7	0.8	1.5	-1.2	-0.4
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.5	-1.2	-0.1
Myopia	0.7	1.0	1.4	0.8	-1.2
Bipolar Disorder or Schizophrenia	0.6	1.5	3.0	0.3	-1.7
Age at First Birth	0.6	0.8	1.4	0.5	1.2
Systolic blood pressure, automated reading	0.6	1.8	1.9	1.4	-1.3
Relative age voice broke	0.6	0.9	0.9	0.9	-0.9
Had other major operations	0.6	0.7	0.8	0.9	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	2.6	1.6	0.6
Weight	0.6	2.8	3.0	-1.6	-1.7
Happiness	0.6	0.8	1.1	1.0	-0.7
Medication for pain relief, constipation, heartburn	0.6	1.0	1.8	-0.4	1.3
Family relationship satisfaction	0.6	0.7	1.0	0.7	-1.0
Illnesses of siblings: Diabetes	0.6	0.7	1.0	-0.6	-1.0
Back pain experienced in last month	0.6	0.9	1.7	0.3	-1.3
Asthma (self-reported)	0.6	1.2	1.9	1.4	0.7
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.4	0.5	-1.2
Irritability	0.6	1.1	1.7	0.7	-1.3
Cholesterol lowering medication	0.6	0.8	1.2	0.7	-1.1
Basal cell carcinoma (self-reported)	0.6	0.7	1.1	0.5	1.0
Schizophrenia (2014)	0.5	1.1	1.9	0.6	-1.4
Ever had hysterectomy (womb removed)	0.5	0.5	1.0	-0.2	1.0
High blood pressure (mother)	0.5	0.7	0.9	-1.0	0.7
Body mass index (BMI)	0.5	2.1	2.3	-1.4	-1.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	2.4	0.9	1.5
Noisy workplace	0.5	0.6	1.0	1.0	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.0	0.5	-1.0
Prospective memory result	0.5	0.7	1.3	0.1	-1.1
Lung cancer (father)	0.5	0.6	0.9	-1.0	-0.6
Pulse wave Arterial Stiffness index	0.5	0.6	0.8	-0.9	0.7
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.0	0.1	-1.4
Wheeze or whistling in the chest in last year	0.5	0.9	1.8	1.3	0.1
Medication: Ibuprofen	0.5	0.7	0.8	0.9	-0.7
Medication: Allopurinol	0.5	0.6	0.8	0.7	0.9
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.1	-1.1	0.3
Osteoarthritis (self-reported)	0.5	0.7	0.7	-0.7	-0.9
Medication: Gliclazide	0.5	0.5	0.8	-0.9	0.6
Average weekly champagne plus white wine intake	0.5	0.7	1.1	1.1	0.5
Guilty feelings	0.5	0.7	1.4	0.2	-1.2
Eye problems/disorders: Glaucoma	0.5	0.7	1.1	1.1	-0.4
Ever depressed for a whole week	0.5	0.7	0.9	-1.0	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.6	1.1	0.1	-1.1
Breast Cancer	0.4	0.9	1.6	-0.4	-1.3
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.7	-0.8	0.4
Ulcerative Colitis	0.4	0.6	0.8	0.6	0.9
Neuroticism	0.4	1.0	2.0	1.4	-0.0
Average weekly spirits intake	0.4	0.5	0.8	0.9	0.5
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.9	-1.0	0.0
High blood pressure	0.4	1.2	2.0	-1.4	-0.6
Medication: Atenolol	0.4	0.5	0.7	0.9	-0.4
Medication: Levothyroxine sodium	0.4	0.8	1.5	0.0	-1.2
Alcohol usually taken with meals	0.4	0.7	0.9	-0.9	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.2	1.1	-0.0
Pain all over the body in last month	0.4	0.4	0.8	-0.0	-0.9
Falls in the last year	0.4	0.6	1.0	0.3	-1.0
Number of live births	0.4	0.5	1.1	-1.0	0.1
Pulse rate	0.4	0.6	1.2	-1.1	0.2
Arm fat mass (right)	0.4	1.8	3.2	-0.5	-1.8
Tense / ‘highly strung’	0.4	0.7	1.4	1.2	0.1
Hair/balding pattern: Pattern 4	0.4	0.9	1.8	-0.1	-1.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	0.7	0.8	-0.8
Medication: Paracetamol	0.4	0.6	1.3	-0.0	-1.1
High blood pressure (siblings)	0.4	0.5	1.0	1.0	0.2
Pulse wave peak to peak time	0.4	0.4	0.5	0.6	-0.7
Emphysema/chronic bronchitis	0.4	0.5	0.8	-0.4	0.9
Leg fat mass (right)	0.4	1.4	2.2	-0.8	-1.5
Number of full sisters	0.4	0.5	0.9	0.2	-1.0
Had major operations	0.4	0.5	1.0	0.2	1.0
Hypertension (Self-reported)	0.4	1.0	1.8	-1.3	-0.6
Mineral and other dietary supplements	0.4	0.5	0.9	-0.1	1.0
Medication: Aspirin	0.4	0.6	1.0	-1.0	-0.4
Smoking status: Current	0.4	0.6	0.9	0.9	0.5
Medication: Paracetamol	0.4	0.6	0.8	0.5	-0.9
Unable to work because of sickness or disability	0.4	0.5	0.9	-1.0	-0.0
Leg fat mass (left)	0.4	1.4	2.3	-0.7	-1.5
Bipolar Disorder (2018)	0.3	0.5	0.8	-0.4	-0.9
Worry (Nagel 2018)	0.3	0.7	0.9	1.0	-0.6
Current tobacco smoking	0.3	0.5	0.5	0.7	0.7
Average weekly fortified wine intake	0.3	0.4	0.5	0.7	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.5	0.6	-0.7
Age when periods started (menarche)	0.3	0.7	1.3	-0.4	-1.1
Supplements: Glucosamine	0.3	0.4	0.7	-0.9	0.3
Past tobacco smoking	0.3	0.5	1.0	1.0	-0.2
Hair/balding pattern: Pattern 2	0.3	0.4	0.4	0.6	-0.6
Arm fat percentage (right)	0.3	1.2	1.2	1.1	-1.1
Hip circumference	0.3	1.4	2.2	-1.5	-0.8
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.5	1.2	-0.0
Medication: Lansoprazole	0.3	0.3	0.5	-0.7	-0.4
Medication: Amlodipine	0.3	0.5	0.5	-0.7	0.7
Whole body fat mass	0.3	1.3	2.3	-0.4	-1.5
Pulse rate, automated reading	0.3	0.8	1.6	-1.3	-0.2
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.6	0.8	0.3
Long-standing illness, disability or infirmity	0.3	0.4	0.7	0.4	0.8
Arm fat mass (left)	0.3	1.3	2.3	-0.6	-1.5
Ever smoked	0.3	0.5	1.0	-1.0	0.1
Number of operations (self-reported)	0.3	0.4	0.9	0.0	-0.9
Risk taking	0.3	0.4	0.8	-0.1	-0.9
Pain experienced in last month	0.3	0.5	0.9	-0.9	0.3
Pack years of smoking	0.3	0.5	0.5	-0.7	0.7
Irritable Bowel Disease (IBD)	0.2	0.4	0.7	-0.3	0.9
Ulcerative Colitis (UC)	0.2	0.3	0.4	-0.7	-0.3
Coronary Artery Disease (CAD)	0.2	0.3	0.5	-0.7	0.3
Blood White Count	0.2	1.2	1.5	1.2	0.9
Systolic Blood Pressure	0.2	1.2	1.5	0.9	-1.2
Hypothyroidism (self reported)	0.2	0.4	0.7	0.2	-0.8
Hand grip strength (left)	0.2	0.4	0.4	-0.7	-0.7
Number of treatments/medications taken	0.2	0.3	0.5	0.7	-0.4
Angina	0.2	0.2	0.5	0.7	0.1
Severe depression (siblings)	0.2	0.2	0.4	-0.3	0.6
Pack years adult smoking proportion	0.2	0.3	0.5	-0.7	0.4
Trunk fat percentage	0.2	0.7	0.8	0.8	-0.9
Hand grip strength (right)	0.2	0.6	1.1	-0.3	-1.0
Stomach or abdominal pain in last month	0.2	0.2	0.3	0.4	0.5
Trunk fat mass	0.2	0.8	1.7	-0.1	-1.3
Waist circumference	0.2	0.9	1.7	-0.3	-1.3
Father’s age at death	0.2	0.2	0.3	-0.4	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.5	0.7	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.3	0.4	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.5	0.7	-0.0
Body fat percentage	0.2	0.7	0.9	0.7	-0.9
Angina (self-reported)	0.2	0.2	0.5	0.7	0.1
Medication: Seretide 50 evohaler	0.2	0.2	0.3	0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.8	-0.9	-0.1
Arm fat percentage (left)	0.2	0.9	1.2	0.7	-1.1
Average weekly red wine intake	0.2	0.2	0.2	-0.5	-0.5
Diabetes diagnosed by doctor	0.2	0.3	0.5	-0.7	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.3	-0.5	-0.5
High cholesterol (Self-reported)	0.2	0.3	0.6	0.8	0.0
Medication: Lisinopril	0.2	0.2	0.3	0.6	0.3
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.3	1.1	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	0.5	-0.5	-0.7
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.2	-0.3	-0.5
Bipolar Disorder (2011)	0.1	0.1	0.3	0.5	0.0
Crohns Disease (2012)	0.1	0.2	0.2	-0.4	0.5
HbA1C	0.1	0.1	0.1	-0.2	0.3
Blood Platelet Count	0.1	1.0	1.8	1.4	-0.4
BMI	0.1	0.4	0.8	-0.9	0.3
Height	0.1	1.7	3.0	0.6	-1.7
Smoking Status	0.1	0.3	0.4	-0.6	-0.4
Hair Pigment	0.1	2.2	3.1	-1.1	1.8
Supplements: Zinc	0.1	0.1	0.1	0.3	0.0
Townsend deprivation index at recruitment	0.1	0.2	0.3	-0.3	-0.6
Sitting height	0.1	1.0	2.0	-1.4	0.2
Number of incorrect matches in round	0.1	0.2	0.3	-0.6	-0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.2	0.4	-0.4
Heart attack	0.1	0.1	0.1	0.3	-0.2
Diabetes (self-reported)	0.1	0.1	0.2	-0.5	-0.1
Time employed in main current job	0.1	0.1	0.1	-0.3	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.5	0.2
Peak expiratory flow (PEF)	0.1	0.1	0.2	0.2	0.4
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	0.3	0.4
Blood clot in the leg (DVT)	0.1	0.1	0.1	0.2	-0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	-0.1	0.4
Leg fat percentage (right)	0.1	0.5	0.7	-0.5	-0.8
Exposure to tobacco smoke outside home	0.1	0.2	0.2	-0.5	-0.4
Qualifications: College or University degree	0.1	0.3	0.6	0.7	0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.2	-0.4	-0.4
Neck or shoulder pain in last month	0.1	0.1	0.2	0.5	-0.2
Comparative height size at age 10	0.1	0.4	0.4	0.6	-0.6
Overall health rating	0.1	0.2	0.3	0.3	-0.5
Medication: Aspirin	0.1	0.1	0.3	-0.5	0.1
Knee pain experienced in last month	0.1	0.2	0.3	-0.4	-0.5
Loneliness, isolation	0.1	0.1	0.3	0.5	0.0
Leg fat percentage (left)	0.1	0.3	0.5	-0.4	-0.7
Age started oral contraceptive pill	0.1	0.2	0.3	-0.1	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	-0.1	-0.4
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.2	-0.1
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.1	0.1
Blood Eosinophil Count	0.0	0.1	0.1	0.0	0.3
Blood Red Count	0.0	0.5	0.8	0.3	0.9
Heel T-Score	0.0	0.2	0.4	-0.1	-0.7
Cardiovascular Disease	0.0	0.0	0.0	-0.0	0.1
Lung FVC	0.0	0.2	0.3	-0.4	-0.5
Tanning	0.0	0.5	0.6	-0.6	-0.8
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.0	-0.0	-0.2
Medication: Co-codamol	0.0	0.0	0.1	0.1	-0.3
Taking other prescription medications	0.0	0.1	0.1	0.3	0.3
Forced vital capacity (FVC)	0.0	0.1	0.1	0.3	-0.1
Qualifications: None of the above	0.0	0.1	0.1	-0.1	-0.3
Medication: Simvastatin	0.0	0.0	0.0	-0.1	-0.1
Fluid intelligence score	0.0	0.1	0.1	0.1	-0.3
Illnesses of siblings	0.0	0.1	0.1	-0.4	0.1
Standing height	0.0	0.4	0.4	-0.7	-0.7
Pulse wave reflection index	0.0	0.0	0.1	-0.2	-0.2
Forced vital capacity (FVC), Best measure	0.0	0.0	0.1	0.1	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.1	0.1	-0.0	0.3
Alcohol intake frequency.	0.0	0.1	0.1	-0.4	0.1
Leg pain on walking	0.0	0.1	0.1	0.3	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.1	0.0	-0.3
Illnesses of father: Heart disease	0.0	0.1	0.1	0.2	0.3
Ever had bowel cancer screening	0.0	0.0	0.0	0.1	0.0
Mouth/teeth dental problems: Mouth ulcers	0.0	0.0	0.0	-0.0	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	-0.3	0.1
Number of self-reported non-cancer illnesses	0.0	0.0	0.0	0.1	-0.1
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.1	0.2	-0.1
Commuting to job workplace: Cycle	0.0	0.0	0.0	0.1	0.0
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	0.3	-0.0

Hub : Genes

DPY19L2P4

Models

Trait associations