Hub : Genes

DPY19L2P4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0560 0.0260 0.00290 0.016 0.013 0.008 0.015 0.006 0.0044 0.0093 0.0310 0.0059 0.056
2 TCGA Prostate Adenocarcinoma 0.0731 0.0351 0.00061 0.025 0.021 0.020 NA 0.022 0.0010 0.0023 0.0029 NA 0.002

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.3 0.5 0.8 -0.4 -0.9
Bipolar Disorder or Schizophrenia 0.6 1.5 3.0 0.3 -1.7
Depressed Affect (Nagel 2018) 2.0 4.1 6.2 2.5 1.4
Depression (Nagel 2018) 0.9 1.4 2.2 0.8 -1.5
Intelligence (Savage-Jansen 2018) 0.1 0.4 0.5 -0.5 -0.7
Neuroticism (Nagel 2018) 1.1 2.5 4.8 2.2 -0.5
Schizophrenia (2018) 0.7 1.4 2.2 0.7 -1.5
Schizophrenia vs Biploar Disorder 0.4 0.6 1.1 0.1 -1.1
Worry (Nagel 2018) 0.3 0.7 0.9 1.0 -0.6
Alzheimer’s Disease (in mother) 1.6 1.9 2.3 -1.2 1.5
Alzheimer’s Disease (in father) 1.5 1.6 1.9 1.4 1.1
Alzheimer’s Disease (including proxy) 0.7 1.0 1.7 -0.6 1.3
Crohns Disease (2017) 0.7 1.5 3.0 0.3 1.7
Irritable Bowel Disease (IBD) 0.2 0.4 0.7 -0.3 0.9
Ulcerative Colitis (UC) 0.2 0.3 0.4 -0.7 -0.3
Major Depression (MDD) 1.9 2.3 4.5 2.1 0.2
Reaction Time 1.2 2.4 4.0 -0.9 -2.0
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.2 -0.3 -0.5
Breast Cancer 0.4 0.9 1.6 -0.4 -1.3
Ovarian Cancer 1.1 1.4 2.9 -0.1 -1.7
Prostate Cancer 1.2 1.7 3.4 -1.9 0.2
Age at First Birth 0.6 0.8 1.4 0.5 1.2
Bipolar Disorder (2011) 0.1 0.1 0.3 0.5 0.0
Body Mass Index (BMI) (2010) 0.0 0.0 0.0 0.2 -0.1
Coronary Artery Disease (CAD) 0.2 0.3 0.5 -0.7 0.3
Crohns Disease (2012) 0.1 0.2 0.2 -0.4 0.5
Mean Putamen Volume 3.0 3.5 4.8 -1.4 2.2
Fasting Glucose 3.5 4.2 7.7 2.8 0.9
HbA1C 0.1 0.1 0.1 -0.2 0.3
HDL Cholesterol 1.1 1.9 2.7 -1.6 -1.1
LDL Cholesterol 0.9 1.4 1.8 -1.3 1.0
Lupus 1.8 2.7 5.0 2.2 0.6
Neuroticism (2016) 1.2 1.7 3.2 1.8 -0.4
Primary Biliary Cirrhosis 0.0 0.0 0.0 0.1 0.1
Rheumatoid Arthritis 1.1 1.5 2.5 1.6 0.6
Schizophrenia (2014) 0.5 1.1 1.9 0.6 -1.4
Triglycerides 1.0 1.6 3.2 1.8 0.2
Type 2 Diabetes (T2D) (2012) 0.4 0.4 0.7 -0.8 0.4
Ulcerative Colitis 0.4 0.6 0.8 0.6 0.9
Blood Eosinophil Count 0.0 0.1 0.1 0.0 0.3
Blood Platelet Count 0.1 1.0 1.8 1.4 -0.4
Blood Red Count 0.0 0.5 0.8 0.3 0.9
Blood White Count 0.2 1.2 1.5 1.2 0.9
Heel T-Score 0.0 0.2 0.4 -0.1 -0.7
BMI 0.1 0.4 0.8 -0.9 0.3
Height 0.1 1.7 3.0 0.6 -1.7
Waist Hip Ratio (WHR) 0.8 3.8 4.1 1.9 -2.0
Systolic Blood Pressure 0.2 1.2 1.5 0.9 -1.2
Smoking Status 0.1 0.3 0.4 -0.6 -0.4
Allergy or Eczema 3.3 8.8 10.8 3.3 2.6
Cardiovascular Disease 0.0 0.0 0.0 -0.0 0.1
Hypothyroidism (self reported) 0.2 0.4 0.7 0.2 -0.8
Respiratory disease 1.0 2.2 2.7 1.3 1.6
Type 2 Diabetes (T2D) (2018) 0.9 1.7 2.6 1.6 0.9
Lung FEV1/FVC ratio 4.2 21.1 40.3 1.3 6.3
Lung FVC 0.0 0.2 0.3 -0.4 -0.5
Neuroticism 0.4 1.0 2.0 1.4 -0.0
Chronotype (morning person) 1.0 2.4 4.6 0.5 2.1
Hair Pigment 0.1 2.2 3.1 -1.1 1.8
Tanning 0.0 0.5 0.6 -0.6 -0.8
Hand grip strength (left) 0.2 0.4 0.4 -0.7 -0.7
Number of treatments/medications taken 0.2 0.3 0.5 0.7 -0.4
Average weekly spirits intake 0.4 0.5 0.8 0.9 0.5
Sensitivity / hurt feelings 0.7 1.2 2.4 1.5 -0.3
Frequency of depressed mood in last 2 weeks 1.6 2.2 2.2 1.5 -1.5
Hearing difficulty/problems: Yes 1.6 2.4 4.8 2.2 0.3
Relative age of first facial hair 1.2 2.5 4.9 -0.4 -2.2
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 0.9 -1.0 0.0
Ever used hormone-replacement therapy (HRT) 0.0 0.0 0.0 -0.0 -0.2
Ever had hysterectomy (womb removed) 0.5 0.5 1.0 -0.2 1.0
Systolic blood pressure, automated reading 0.6 1.8 1.9 1.4 -1.3
Eye problems/disorders: Diabetes related eye disease 1.0 1.2 2.3 -1.5 0.2
Angina 0.2 0.2 0.5 0.7 0.1
Medication for hormone replacement therapy 0.7 0.8 0.8 -0.9 -0.9
Vitamin and mineral supplements 1.1 1.5 1.8 1.1 1.3
Supplements: Zinc 0.1 0.1 0.1 0.3 0.0
Medication: Co-codamol 0.0 0.0 0.1 0.1 -0.3
Medication: Metformin 1.6 2.3 4.6 -2.1 0.1
Diabetes (father) 1.8 2.2 3.0 1.2 1.7
Diabetes (mother) 1.4 1.8 3.5 1.9 0.3
Severe depression (siblings) 0.2 0.2 0.4 -0.3 0.6
Pack years adult smoking proportion 0.2 0.3 0.5 -0.7 0.4
Impedance of leg (right) 1.0 4.8 6.0 2.4 1.9
Leg fat-free mass (left) 1.1 5.7 5.9 -2.4 -2.4
Trunk fat percentage 0.2 0.7 0.8 0.8 -0.9
Hand grip strength (right) 0.2 0.6 1.1 -0.3 -1.0
Townsend deprivation index at recruitment 0.1 0.2 0.3 -0.3 -0.6
Current tobacco smoking 0.3 0.5 0.5 0.7 0.7
Average weekly fortified wine intake 0.3 0.4 0.5 0.7 -0.6
Maternal smoking around birth 3.6 5.2 8.7 3.0 1.3
Fed-up feelings 1.5 2.8 4.7 2.2 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.5 0.6 -0.7
Relative age voice broke 0.6 0.9 0.9 0.9 -0.9
Taking other prescription medications 0.0 0.1 0.1 0.3 0.3
Age when periods started (menarche) 0.3 0.7 1.3 -0.4 -1.1
Bilateral oophorectomy (both ovaries removed) 1.2 1.3 1.8 -0.9 -1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.6 2.5 1.6 0.8
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 1.9 -1.4 0.7
Qualifications: CSEs or equivalent 0.8 1.0 1.1 1.0 1.1
Serious illness, injury or assault to yourself 0.8 1.0 1.8 1.4 0.3
High blood pressure 0.4 1.2 2.0 -1.4 -0.6
Hayfever, allergic rhinitis or eczema 2.5 5.4 6.0 2.5 2.2
Multivitamins +/- minerals 0.7 0.9 0.9 -0.9 -0.9
Stomach or abdominal pain in last month 0.2 0.2 0.3 0.4 0.5
Supplements: Glucosamine 0.3 0.4 0.7 -0.9 0.3
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 1.9 1.4 0.8
Medication: Atenolol 0.4 0.5 0.7 0.9 -0.4
Medication: Levothyroxine sodium 0.4 0.8 1.5 0.0 -1.2
Sitting height 0.1 1.0 2.0 -1.4 0.2
Chronic bronchitis/emphysema (father) 1.3 1.6 2.6 0.7 -1.6
High blood pressure (mother) 0.5 0.7 0.9 -1.0 0.7
Body mass index (BMI) 0.5 2.1 2.3 -1.4 -1.5
Impedance of leg (left) 1.2 6.0 7.5 2.7 2.1
Leg predicted mass (left) 1.0 5.3 5.4 -2.3 -2.3
Trunk fat mass 0.2 0.8 1.7 -0.1 -1.3
Waist circumference 0.2 0.9 1.7 -0.3 -1.3
Number of incorrect matches in round 0.1 0.2 0.3 -0.6 -0.2
Past tobacco smoking 0.3 0.5 1.0 1.0 -0.2
Alcohol usually taken with meals 0.4 0.7 0.9 -0.9 -0.7
Nervous feelings 0.8 1.5 1.7 1.3 -1.1
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.2 1.1 -0.0
Hearing difficulty/problems with background noise 1.6 2.5 4.9 2.2 -0.3
Hair/balding pattern: Pattern 2 0.3 0.4 0.4 0.6 -0.6
Had menopause 1.0 1.2 2.1 -1.4 -0.6
Had other major operations 0.6 0.7 0.8 0.9 0.8
Forced vital capacity (FVC) 0.0 0.1 0.1 0.3 -0.1
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.5 2.6 1.6 0.6
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 0.2 0.4 -0.4
Qualifications: None of the above 0.0 0.1 0.1 -0.1 -0.3
Financial difficulties in last 2 years 1.0 1.4 2.0 1.4 -0.9
Mouth/teeth dental problems 0.9 1.4 2.4 0.7 1.5
Heart attack 0.1 0.1 0.1 0.3 -0.2
Allergy 1.6 3.7 4.8 -2.2 -1.6
Pain all over the body in last month 0.4 0.4 0.8 -0.0 -0.9
Diabetes (self-reported) 0.1 0.1 0.2 -0.5 -0.1
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 1.4 0.8 1.2
Medication: Ramipril 1.9 2.5 2.6 -1.6 -1.6
Medication: Simvastatin 0.0 0.0 0.0 -0.1 -0.1
Fluid intelligence score 0.0 0.1 0.1 0.1 -0.3
Illnesses of siblings 0.0 0.1 0.1 -0.4 0.1
Neuroticism score 0.8 1.6 3.1 1.8 0.1
Weight 0.6 2.8 3.0 -1.6 -1.7
Impedance of arm (right) 2.3 10.9 20.7 4.6 1.1
Arm fat percentage (right) 0.3 1.2 1.2 1.1 -1.1
Trunk fat-free mass 1.5 8.8 12.9 -3.6 -2.1
Hip circumference 0.3 1.4 2.2 -1.5 -0.8
Time employed in main current job 0.1 0.1 0.1 -0.3 -0.3
Alcohol intake versus 10 years previously 1.7 2.5 5.1 2.2 -0.2
Father’s age at death 0.2 0.2 0.3 -0.4 -0.6
Worrier / anxious feelings 0.8 1.5 2.5 1.6 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.5 0.7 -0.3
Falls in the last year 0.4 0.6 1.0 0.3 -1.0
Hair/balding pattern: Pattern 3 0.8 1.2 2.3 -1.5 0.4
Number of live births 0.4 0.5 1.1 -1.0 0.1
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 2.4 0.9 1.5
Pulse rate 0.4 0.6 1.2 -1.1 0.2
Happiness 0.6 0.8 1.1 1.0 -0.7
Noisy workplace 0.5 0.6 1.0 1.0 -0.4
Qualifications: A levels/AS levels or equivalent 0.3 0.7 1.5 1.2 -0.0
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.2 0.5 0.2
Mouth/teeth dental problems: Dentures 0.9 1.5 2.8 0.4 1.7
Asthma 0.7 1.3 2.1 1.4 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.0 0.5 -1.0
Medication: Cholesterol lowering 1.0 1.5 2.1 1.4 1.0
Depression (self-reported) 1.9 2.3 4.4 2.1 -0.3
Medication: Lansoprazole 0.3 0.3 0.5 -0.7 -0.4
Prospective memory result 0.5 0.7 1.3 0.1 -1.1
Lung cancer (father) 0.5 0.6 0.9 -1.0 -0.6
Illnesses of mother 1.3 1.6 2.3 1.0 -1.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 1.3 0.4 1.1
Pulse wave Arterial Stiffness index 0.5 0.6 0.8 -0.9 0.7
Impedance of arm (left) 2.3 10.8 19.0 4.4 1.6
Arm fat mass (right) 0.4 1.8 3.2 -0.5 -1.8
Trunk predicted mass 1.6 9.0 13.1 -3.6 -2.2
Standing height 0.0 0.4 0.4 -0.7 -0.7
Length of working week for main job 3.2 3.6 4.4 2.1 1.6
Exposure to tobacco smoke at home 1.0 1.1 1.7 -0.7 -1.3
Breastfed as a baby 2.4 3.0 5.7 -2.4 0.6
Tense / ‘highly strung’ 0.4 0.7 1.4 1.2 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.2 0.5 0.7 -0.0
Hair/balding pattern: Pattern 4 0.4 0.9 1.8 -0.1 -1.4
Birth weight of first child 1.4 2.6 5.1 -0.3 2.3
Peak expiratory flow (PEF) 0.1 0.1 0.2 0.2 0.4
Pulse wave reflection index 0.0 0.0 0.1 -0.2 -0.2
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.2 0.3 0.4
Loud music exposure frequency 1.5 1.7 2.2 1.1 -1.5
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 0.7 0.8 -0.8
Mouth/teeth dental problems: Bleeding gums 2.1 2.8 5.4 -0.3 -2.3
Blood clot in the leg (DVT) 0.1 0.1 0.1 0.2 -0.3
Medication: Paracetamol 0.4 0.6 1.3 -0.0 -1.1
Headache pain in last month 2.1 3.7 5.1 2.3 1.5
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 2.9 -0.3 -1.7
Glaucoma (self-reported) 0.7 0.8 1.1 1.0 -0.7
Gout (self-reported) 1.1 1.5 1.7 1.1 1.3
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.0 0.1 -1.4
Medication: Amlodipine 0.3 0.5 0.5 -0.7 0.7
Medication: Ventolin 100micrograms inhaler 1.9 2.4 3.5 1.9 1.2
Birth weight 1.6 3.4 4.3 -2.1 1.6
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.2 -0.1 0.4
High blood pressure (siblings) 0.4 0.5 1.0 1.0 0.2
Forced vital capacity (FVC), Best measure 0.0 0.0 0.1 0.1 -0.2
Body fat percentage 0.2 0.7 0.9 0.7 -0.9
Leg fat percentage (right) 0.1 0.5 0.7 -0.5 -0.8
Arm fat-free mass (right) 2.1 10.6 16.4 -4.0 -2.2
Exposure to tobacco smoke outside home 0.1 0.2 0.2 -0.5 -0.4
Comparative body size at age 10 0.8 2.2 3.1 1.2 -1.8
Number of full brothers 0.7 0.9 0.9 0.9 1.0
Worry too long after embarrassment 1.8 3.0 5.6 2.4 0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.5 1.6 -0.3
Wheeze or whistling in the chest in last year 0.5 0.9 1.8 1.3 0.1
Number of children fathered 2.4 2.7 5.4 0.1 2.3
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 1.5 -1.2 0.9
Age at first live birth 2.0 3.6 5.1 2.3 1.4
Pulse wave peak to peak time 0.4 0.4 0.5 0.6 -0.7
Health satisfaction 0.7 0.9 1.6 -0.5 -1.3
Shortness of breath walking on level ground 1.0 1.2 2.1 -0.5 -1.5
Qualifications: College or University degree 0.1 0.3 0.6 0.7 0.2
Eye problems/disorders: None of the above 1.0 1.1 1.3 0.9 -1.2
Mouth/teeth dental problems: Loose teeth 0.1 0.2 0.2 -0.4 -0.4
Emphysema/chronic bronchitis 0.4 0.5 0.8 -0.4 0.9
Medication for pain relief, constipation, heartburn 0.6 1.0 1.8 -0.4 1.3
Neck or shoulder pain in last month 0.1 0.1 0.2 0.5 -0.2
Medication: Blood pressure 1.6 2.8 3.1 -1.8 1.6
Angina (self-reported) 0.2 0.2 0.5 0.7 0.1
Migraine (self-reported) 4.3 5.4 8.7 3.0 1.4
Medication: Ibuprofen 0.5 0.7 0.8 0.9 -0.7
Medication: Allopurinol 0.5 0.6 0.8 0.7 0.9
Medication: Omeprazole 2.4 2.9 5.0 2.2 0.8
Medication: Seretide 50 evohaler 0.2 0.2 0.3 0.6 -0.1
Mean time to correctly identify matches 1.2 2.2 2.2 -1.5 -1.5
Heart disease (mother) 1.7 2.1 3.4 -0.9 1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.0 0.1 0.1 -0.0 0.3
Whole body fat mass 0.3 1.3 2.3 -0.4 -1.5
Leg fat mass (right) 0.4 1.4 2.2 -0.8 -1.5
Arm predicted mass (right) 2.2 11.3 17.2 -4.2 -2.3
Pulse rate, automated reading 0.3 0.8 1.6 -1.3 -0.2
Alcohol intake frequency. 0.0 0.1 0.1 -0.4 0.1
Comparative height size at age 10 0.1 0.4 0.4 0.6 -0.6
Number of full sisters 0.4 0.5 0.9 0.2 -1.0
Suffer from ‘nerves’ 1.0 1.6 3.1 -0.1 -1.8
Overall health rating 0.1 0.2 0.3 0.3 -0.5
Chest pain or discomfort 0.7 1.0 1.9 -1.4 0.2
Had major operations 0.4 0.5 1.0 0.2 1.0
Age at last live birth 1.4 2.1 2.7 1.2 1.6
Family relationship satisfaction 0.6 0.7 1.0 0.7 -1.0
Leg pain on walking 0.0 0.1 0.1 0.3 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.1 0.1 0.0 -0.3
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.6 0.8 0.3
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 1.2 -0.9 -1.1
Medication: Aspirin 0.1 0.1 0.3 -0.5 0.1
Supplements: Vitamin C 1.1 1.3 1.6 -1.0 -1.3
Knee pain experienced in last month 0.1 0.2 0.3 -0.4 -0.5
Hypertension (Self-reported) 0.4 1.0 1.8 -1.3 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.6 1.8 3.6 1.9 0.3
Illnesses of father: Heart disease 0.0 0.1 0.1 0.2 0.3
Illnesses of siblings: Diabetes 0.6 0.7 1.0 -0.6 -1.0
Smoking status: Previous 1.0 1.5 2.9 -1.7 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.8 -0.9 -0.1
Whole body fat-free mass 1.4 7.8 10.5 -3.2 -2.3
Leg fat-free mass (right) 1.0 5.3 5.3 -2.3 -2.3
Arm fat percentage (left) 0.2 0.9 1.2 0.7 -1.1
Average weekly red wine intake 0.2 0.2 0.2 -0.5 -0.5
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.1 -1.1 0.3
Mood swings 0.9 1.7 2.2 1.5 1.1
Loneliness, isolation 0.1 0.1 0.3 0.5 0.0
Long-standing illness, disability or infirmity 0.3 0.4 0.7 0.4 0.8
Ever had bowel cancer screening 0.0 0.0 0.0 0.1 0.0
Diabetes diagnosed by doctor 0.2 0.3 0.5 -0.7 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 4.1 4.4 4.4 -2.1 2.1
Friendships satisfaction 0.8 1.0 1.2 1.1 -0.9
Qualifications: nursing, teaching 1.5 2.3 4.4 -0.6 -2.1
Commuting to job workplace: Walk 1.4 1.5 2.1 -0.9 -1.5
Eye problems/disorders: Cataract 1.5 1.8 3.4 -1.9 0.3
Mouth/teeth dental problems: Mouth ulcers 0.0 0.0 0.0 -0.0 -0.1
Medication for cholesterol 3.4 5.1 10.2 0.2 3.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.0 0.0 0.1 -0.3 0.1
Back pain experienced in last month 0.6 0.9 1.7 0.3 -1.3
Mineral and other dietary supplements 0.4 0.5 0.9 -0.1 1.0
Breast cancer (self-reported) 0.7 0.9 1.2 1.1 0.7
Asthma (self-reported) 0.6 1.2 1.9 1.4 0.7
Osteoporosis (self-reported) 2.2 2.8 3.6 1.4 -1.9
Osteoarthritis (self-reported) 0.5 0.7 0.7 -0.7 -0.9
Medication: Aspirin 0.4 0.6 1.0 -1.0 -0.4
Medication: Gliclazide 0.5 0.5 0.8 -0.9 0.6
Illnesses of father: None of the above (group 1) 0.7 0.8 1.5 -1.2 -0.4
Smoking status: Current 0.4 0.6 0.9 0.9 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.0 4.3 7.6 1.0 2.8
Whole body water mass 1.4 7.8 10.8 -3.3 -2.2
Leg predicted mass (right) 0.9 5.1 5.2 -2.2 -2.3
Arm fat mass (left) 0.3 1.3 2.3 -0.6 -1.5
Number of self-reported non-cancer illnesses 0.0 0.0 0.0 0.1 -0.1
Average weekly champagne plus white wine intake 0.5 0.7 1.1 1.1 0.5
Miserableness 1.4 2.4 4.7 2.2 -0.4
Guilty feelings 0.5 0.7 1.4 0.2 -1.2
Wears glasses or contact lenses 2.1 2.4 4.8 -2.2 0.1
Ever taken oral contraceptive pill 1.7 1.9 1.9 1.4 1.4
Hearing aid user 0.8 0.9 1.1 -0.8 1.1
Mother’s age at death 1.3 1.7 3.3 0.2 -1.8
Financial situation satisfaction 1.1 1.4 2.8 0.3 -1.7
Tinnitus: Yes, now most or all of the time 0.2 0.3 0.3 -0.5 -0.5
Commuting to job workplace: Public transport 1.1 1.3 1.8 -1.3 -0.9
Eye problems/disorders: Glaucoma 0.5 0.7 1.1 1.1 -0.4
Medication: Blood pressure 1.0 1.9 3.5 -0.6 -1.9
Pain type(s) experienced in last month: Hip pain 0.0 0.0 0.1 0.2 -0.1
Supplements: Fish oil (including cod liver oil) 0.6 0.8 1.4 0.5 -1.2
High cholesterol (Self-reported) 0.2 0.3 0.6 0.8 0.0
Medication: Bendroflumethiazide 1.2 1.8 3.5 -0.3 -1.9
Medication: Paracetamol 0.4 0.6 0.8 0.5 -0.9
Medication: Lisinopril 0.2 0.2 0.3 0.6 0.3
Medication: Atorvastatin 2.1 2.6 3.3 1.4 1.8
Illnesses of father: High blood pressure 1.9 2.3 3.5 1.9 1.1
Alcohol drinker status: Never 1.3 1.5 2.2 0.9 1.5
Ever smoked 0.3 0.5 1.0 -1.0 0.1
Basal metabolic rate 1.1 6.3 7.6 -2.8 -2.2
Leg fat percentage (left) 0.1 0.3 0.5 -0.4 -0.7
Arm fat-free mass (left) 1.7 8.7 13.9 -3.7 -1.9
Number of operations (self-reported) 0.3 0.4 0.9 0.0 -0.9
Average weekly beer plus cider intake 1.3 1.9 2.0 1.4 1.4
Irritability 0.6 1.1 1.7 0.7 -1.3
Risk taking 0.3 0.4 0.8 -0.1 -0.9
Ever had prostate specific antigen (PSA) test 0.7 0.8 1.5 -1.2 -0.1
Fractured/broken bones in last 5 years 2.6 3.3 4.1 2.0 1.6
Age started oral contraceptive pill 0.1 0.2 0.3 -0.1 -0.6
Diastolic blood pressure, automated reading 4.2 13.1 23.7 -1.6 -4.9
Ever depressed for a whole week 0.5 0.7 0.9 -1.0 -0.6
Unable to work because of sickness or disability 0.4 0.5 0.9 -1.0 -0.0
Commuting to job workplace: Cycle 0.0 0.0 0.0 0.1 0.0
Myopia 0.7 1.0 1.4 0.8 -1.2
Vascular/heart problems diagnosed by doctor 0.2 0.7 1.3 1.1 0.2
Cholesterol lowering medication 0.6 0.8 1.2 0.7 -1.1
Medication: Omeprazole (e.g. Zanprol) 3.3 4.0 6.8 2.6 1.1
Pain experienced in last month 0.3 0.5 0.9 -0.9 0.3
Supplements: Calcium 2.7 3.0 4.9 -1.1 -2.2
Basal cell carcinoma (self-reported) 0.6 0.7 1.1 0.5 1.0
Heart attack/myocardial infarction (self-reported) 0.0 0.0 0.1 0.3 -0.0
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.2 -0.1 -0.4
Heart disease (siblings) 1.5 1.9 3.8 1.9 -0.0
Alcohol drinker status: Previous 1.0 1.1 1.4 -1.2 0.9
Pack years of smoking 0.3 0.5 0.5 -0.7 0.7
Impedance of whole body 2.0 10.0 15.9 4.0 2.0
Leg fat mass (left) 0.4 1.4 2.3 -0.7 -1.5
Arm predicted mass (left) 1.8 9.0 13.2 -3.6 -2.2