Hub : Genes

ZNF260

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1020	0.0340	2.2e-07	0.077	0.062	0.077	0.066	0.069	1.3e-09	5.3e-08	1.0e-09	1.8e-08	8.9e-09
2	GTEx	Artery Tibial	0.0852	0.0355	2.5e-04	0.023	NA	0.014	NA	0.020	5.9e-03	NA	2.8e-02	NA	9.5e-03
3	GTEx	Cells EBV-transformed lymphocytes	0.2610	0.0930	1.6e-03	0.087	NA	0.109	NA	0.131	9.1e-04	NA	2.0e-04	NA	4.8e-05
4	GTEx	Cells Transformed fibroblasts	0.1210	0.0480	2.8e-04	0.072	NA	0.059	NA	0.078	4.5e-06	NA	3.1e-05	NA	1.9e-06
5	GTEx	Esophagus Mucosa	0.3400	0.0670	4.7e-15	0.312	NA	0.300	NA	0.308	2.5e-21	NA	2.2e-20	NA	4.9e-21
6	GTEx	Esophagus Muscularis	0.0660	0.0310	5.3e-03	0.098	NA	0.072	NA	0.091	1.6e-06	NA	3.9e-05	NA	3.6e-06
7	GTEx	Nerve Tibial	0.0554	0.0249	2.6e-03	0.023	NA	0.024	NA	0.023	9.2e-03	NA	7.4e-03	NA	8.6e-03
8	GTEx	Pancreas	0.1170	0.0480	1.2e-03	0.055	NA	0.041	NA	0.056	2.3e-03	NA	7.6e-03	NA	2.1e-03
9	GTEx	Pituitary	0.3980	0.2020	1.8e-03	0.112	NA	0.055	NA	0.083	9.7e-04	NA	1.6e-02	NA	4.1e-03
10	GTEx	Prostate	0.2330	0.0770	1.8e-04	0.174	NA	0.171	NA	0.156	3.8e-05	NA	4.4e-05	NA	9.9e-05
11	GTEx	Skin Not Sun Exposed Suprapubic	0.0840	0.0430	5.4e-03	0.016	NA	0.007	NA	0.010	4.1e-02	NA	1.2e-01	NA	8.4e-02
12	GTEx	Thyroid	0.0710	0.0290	6.0e-04	0.081	NA	0.088	NA	0.084	8.8e-07	NA	3.0e-07	NA	5.7e-07
13	NTR	Blood	0.0339	0.0113	3.6e-08	0.017	0.028	0.025	0.028	0.022	3.1e-06	1.3e-09	1.1e-08	2.3e-09	1.0e-07
14	TCGA	Brain Lower Grade Glioma	0.0565	0.0295	5.5e-05	0.037	0.038	0.024	NA	0.042	4.5e-05	3.5e-05	8.3e-04	NA	1.5e-05
15	TCGA	Liver Hepatocellular Carcinoma	0.0990	0.0580	5.1e-03	0.014	0.017	0.005	NA	0.000	7.2e-02	5.0e-02	1.9e-01	NA	3.1e-01
16	TCGA	Pheochromocytoma and Paraganglioma	0.1210	0.0640	4.2e-04	0.099	0.100	0.074	NA	0.089	9.8e-05	8.6e-05	7.0e-04	NA	2.1e-04
17	TCGA	Prostate Adenocarcinoma	0.1024	0.0628	2.1e-04	0.023	0.040	0.038	NA	0.037	1.7e-03	4.6e-05	7.3e-05	NA	8.8e-05
18	TCGA	Thyroid Carcinoma	0.1080	0.0440	2.1e-08	0.092	0.079	0.077	NA	0.079	2.9e-09	3.9e-08	6.3e-08	NA	3.9e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	0.5	0.9	2.3	0.5	-1.5	0.6	-0.6	-0.9	-0.7	-0.1	0.9	-0.3	-1.3	-0.2	-1.3	1.0	-0.8	0.1	-1.3	-1.2	-1.3
Bipolar Disorder or Schizophrenia	0.4	1.0	2.6	1.0	-1.2	1.0	-1.1	-1.2	-1.0	-0.1	1.6	-0.7	-0.9	-1.2	-1.5	0.1	-1.1	-0.1	-1.4	-0.7	-0.7
Depressed Affect (Nagel 2018)	0.8	1.7	10.1	0.5	-0.3	-0.8	1.7	0.4	0.4	1.7	1.8	1.8	-0.0	1.2	0.3	1.6	0.7	3.2	1.4	0.1	0.1
Depression (Nagel 2018)	2.4	3.5	11.9	1.1	0.3	-1.5	3.0	1.3	1.4	2.6	1.4	3.0	1.0	2.8	1.1	0.8	1.5	3.5	2.1	0.4	0.4
Intelligence (Savage-Jansen 2018)	2.2	6.9	11.3	3.4	0.8	-1.9	3.3	3.1	3.4	3.3	2.2	3.1	2.1	2.5	2.4	-0.8	3.0	2.5	2.7	2.3	2.7
Neuroticism (Nagel 2018)	0.3	0.7	2.2	-0.8	-0.9	-0.8	0.3	-1.1	-1.2	-0.2	0.4	-0.1	-0.9	0.1	-1.1	1.5	-1.0	1.2	-0.2	-0.4	-1.0
Schizophrenia (2018)	0.3	0.6	1.8	0.9	-0.4	0.8	-0.9	-0.8	-0.7	-0.1	1.3	-0.7	-0.1	-1.3	-0.9	-0.7	-0.7	-0.2	-0.8	0.1	0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	2.0	-0.2	0.3	1.4	-1.4	-0.5	-0.6	-0.5	0.8	-1.0	0.5	-1.2	-0.3	-0.9	-0.2	-0.6	-0.4	-0.1	0.5
Worry (Nagel 2018)	0.3	0.7	2.0	-0.8	-1.0	0.1	-0.3	-1.3	-1.3	-1.1	-0.4	-0.9	-0.7	-0.4	-1.2	0.6	-1.4	0.1	-0.6	0.2	-0.6
Alzheimer’s Disease (in mother)	1.8	2.2	10.8	-1.2	-2.1	0.9	-0.2	-1.3	-1.1	-0.5	0.2	0.1	-2.7	-0.3	-1.6	3.3	-1.4	0.8	-0.9	-1.6	-1.5
Alzheimer’s Disease (in father)	0.8	0.9	1.3	0.7	1.1	-1.1	0.8	1.0	1.0	0.8	0.4	0.8	1.1	0.6	1.1	-1.1	1.1	0.4	1.0	1.1	1.0
Alzheimer’s Disease (including proxy)	0.4	0.6	3.0	-0.5	-1.2	0.3	0.3	-0.6	-0.4	0.0	0.7	0.2	-1.3	-0.1	-0.9	1.7	-0.6	0.7	-0.4	-0.6	-0.6
Crohns Disease (2017)	3.5	7.7	12.2	-3.2	-3.4	2.2	-3.1	-2.5	-2.5	-3.1	-1.6	-2.9	-2.9	-2.8	-2.4	3.5	-2.4	-2.1	-3.1	-2.7	-3.0
Irritable Bowel Disease (IBD)	0.6	1.4	4.0	-1.8	-1.9	0.3	-0.8	-1.2	-1.2	-1.4	-0.7	-1.2	-0.7	-1.2	-1.0	2.0	-1.1	0.2	-0.7	-0.9	-1.1
Ulcerative Colitis (UC)	0.5	0.8	4.7	0.3	-0.3	-1.3	1.3	0.3	0.3	0.8	0.9	0.7	1.1	0.2	0.5	0.2	0.5	2.2	1.3	0.6	0.8
Major Depression (MDD)	2.5	3.0	7.3	1.7	1.3	-2.4	2.5	1.6	1.5	1.8	0.4	2.7	0.4	2.2	1.6	0.2	1.6	2.3	2.1	1.4	0.8
Reaction Time	2.4	4.6	10.4	1.1	3.2	-3.1	2.2	1.7	1.5	2.5	1.4	2.1	1.6	2.3	1.9	-2.2	1.9	2.5	2.5	1.7	1.6
Verbal and Numeric Reasoning (VNR)	1.5	3.6	5.9	2.4	1.0	-1.8	2.3	2.2	2.4	2.2	1.1	2.2	2.1	1.4	1.7	-1.2	2.0	1.5	1.9	1.8	2.1
Breast Cancer	1.1	2.6	6.8	0.8	2.5	-2.6	1.4	1.6	1.5	1.1	-0.1	1.3	1.8	1.7	1.7	-2.3	1.4	0.7	1.7	1.5	1.6
Ovarian Cancer	1.8	2.4	4.3	-2.0	-0.5	0.9	-1.4	-1.7	-1.9	-1.7	-1.7	-1.2	-1.8	-1.8	-1.3	1.5	-1.7	-1.2	-1.4	-1.5	-2.1
Prostate Cancer	0.4	0.5	1.1	-0.2	-0.6	0.5	-1.1	-0.8	-0.9	-0.7	-0.5	-0.7	-0.3	-1.0	-0.9	-0.4	-0.8	-0.8	-0.9	-0.9	-0.5
Age at First Birth	0.2	0.2	0.7	0.6	-0.2	0.3	-0.1	0.8	0.8	0.2	-0.0	0.4	0.0	0.1	0.8	0.8	0.7	-0.1	0.2	0.2	0.3
Bipolar Disorder (2011)	0.6	0.6	3.3	1.5	-0.7	-0.2	0.4	0.0	0.3	1.0	1.8	0.3	-0.9	0.9	-0.5	0.4	-0.1	0.1	-0.6	-0.5	-0.3
Body Mass Index (BMI) (2010)	0.9	1.3	3.3	1.8	0.8	-0.3	0.7	1.1	1.1	1.3	1.7	0.9	1.3	0.7	1.0	-1.0	1.2	0.7	1.1	1.1	1.4
Coronary Artery Disease (CAD)	0.4	0.5	2.3	-0.0	0.9	-0.9	0.3	0.1	-0.1	0.9	1.5	0.4	0.9	0.7	0.3	-0.6	0.4	1.5	0.6	-0.2	0.4
Crohns Disease (2012)	4.5	7.2	17.2	-2.2	-3.4	2.0	-2.4	-2.7	-2.6	-2.0	0.1	-2.1	-3.7	-2.2	-2.8	4.2	-2.3	-0.5	-3.0	-3.3	-3.5
Mean Putamen Volume	0.7	0.8	4.3	-0.1	-0.2	-0.2	0.6	-0.4	-0.4	1.3	1.7	0.8	-0.4	0.6	-0.4	1.1	0.1	2.1	0.3	-1.1	-0.6
Fasting Glucose	0.4	0.5	2.1	0.9	-0.4	0.1	0.4	0.3	0.3	0.9	1.5	0.6	0.3	-0.0	0.2	0.8	0.6	1.4	0.6	0.2	0.7
HbA1C	3.9	4.3	8.2	-2.3	-1.8	2.9	-2.6	-2.1	-2.2	-1.7	-0.8	-2.4	-2.0	-2.2	-1.8	1.6	-1.8	-1.4	-2.2	-2.5	-2.1
HDL Cholesterol	1.6	2.7	4.7	-1.8	-1.5	0.6	-1.3	-1.6	-1.6	-2.0	-2.1	-1.6	-2.2	-1.9	-1.4	1.2	-1.7	-1.7	-1.7	-1.3	-1.8
LDL Cholesterol	0.1	0.2	2.3	-0.7	0.1	-1.5	0.2	-0.3	-0.3	0.0	-0.1	-0.0	0.3	0.1	-0.1	0.1	-0.2	0.4	0.1	-0.1	-0.4
Lupus	0.3	0.4	3.0	-0.5	0.6	-1.7	-0.3	-0.2	-0.3	-0.3	0.7	-0.2	1.2	-0.2	0.0	-0.5	-0.2	0.2	0.3	0.9	0.8
Neuroticism (2016)	0.4	0.5	3.6	0.0	-0.2	-1.9	1.1	-0.2	-0.2	0.3	-0.2	1.0	-0.4	-0.1	-0.2	0.7	-0.1	1.3	0.5	0.1	-0.5
Primary Biliary Cirrhosis	6.8	9.7	15.7	-3.3	-3.1	2.3	-3.1	-3.8	-4.0	-3.2	-1.8	-3.5	-3.2	-3.0	-3.5	2.6	-3.6	-1.9	-3.3	-2.9	-3.2
Rheumatoid Arthritis	1.4	1.9	3.4	1.6	1.2	-0.6	0.7	1.7	1.7	1.6	1.8	0.6	1.7	1.4	1.6	-1.7	1.8	0.2	1.0	1.1	1.6
Schizophrenia (2014)	0.5	1.1	2.9	0.7	-0.8	1.6	-1.7	-1.1	-1.0	-0.8	0.7	-1.2	-0.3	-1.5	-1.2	-0.7	-1.1	-1.0	-1.5	-0.2	-0.4
Triglycerides	0.2	0.4	1.6	0.5	0.2	-0.3	0.9	0.3	0.3	1.0	0.6	1.1	0.2	0.9	0.2	0.1	0.4	1.3	0.6	-0.4	-0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	3.7	-0.1	-1.5	0.8	-0.3	-0.6	-0.6	-0.1	1.5	-0.0	-0.8	-0.3	-0.7	1.9	-0.3	0.7	-0.3	-0.7	-0.4
Ulcerative Colitis	0.2	0.3	1.2	-0.5	0.1	-1.0	0.2	-0.5	-0.6	-0.1	0.6	-0.2	1.0	0.6	-0.1	-0.4	-0.3	1.1	0.5	0.1	0.2
Blood Eosinophil Count	1.8	14.2	43.3	-3.2	-5.7	2.6	-2.9	-4.1	-4.1	-3.0	-0.4	-3.0	-4.4	-3.1	-4.0	6.6	-3.8	-0.3	-3.3	-4.1	-4.0
Blood Platelet Count	0.3	3.9	29.7	3.3	0.9	-0.3	-0.3	0.8	1.3	2.6	5.5	0.8	2.0	1.5	0.2	-2.4	1.3	1.4	0.1	-0.5	1.6
Blood Red Count	0.5	4.8	9.3	0.6	3.0	-3.0	2.4	2.2	2.0	2.2	-0.4	2.0	2.4	2.7	2.6	-1.6	2.6	1.7	2.6	1.8	1.6
Blood White Count	0.3	2.2	6.6	2.6	0.9	0.3	1.3	1.5	1.9	2.4	1.7	1.7	1.2	1.9	0.9	-1.2	1.6	1.2	0.7	0.1	0.6
Heel T-Score	0.4	2.8	6.8	1.5	1.0	-0.5	2.6	1.5	1.6	1.6	1.0	2.3	1.4	1.8	1.4	-0.5	1.4	2.0	2.2	2.2	1.8
BMI	0.4	2.1	6.1	1.5	1.0	-2.3	1.4	0.7	0.8	2.4	2.4	1.6	0.3	1.4	0.5	-0.8	1.2	2.5	1.1	-0.1	0.4
Height	1.3	24.9	93.3	-4.3	-8.3	3.0	-3.1	-5.4	-5.4	-4.2	-0.8	-3.6	-6.2	-4.9	-5.2	9.7	-5.1	1.0	-3.5	-3.6	-4.3
Waist Hip Ratio (WHR)	0.6	2.9	10.2	0.7	2.9	-0.6	0.4	1.8	1.6	0.5	0.2	0.1	2.3	0.1	2.1	-3.2	1.6	-1.9	1.2	2.0	2.1
Systolic Blood Pressure	1.0	5.1	12.7	-3.4	-2.4	0.2	-2.2	-2.5	-2.7	-2.3	-0.4	-2.3	-2.3	-2.3	-2.2	3.6	-2.2	-0.2	-1.9	-2.2	-2.2
Smoking Status	2.6	6.3	12.6	-3.0	-0.9	0.5	-2.8	-2.6	-2.7	-3.1	-2.4	-3.5	-1.4	-3.1	-2.2	0.2	-2.7	-3.6	-2.9	-1.8	-2.3
Allergy or Eczema	1.3	3.4	5.7	-1.8	-1.7	1.0	-1.6	-1.9	-2.0	-2.4	-1.6	-2.0	-1.9	-1.8	-1.8	2.2	-2.1	-1.3	-1.8	-1.8	-2.3
Cardiovascular Disease	0.2	0.6	3.3	-1.8	0.4	-1.4	-0.7	-0.7	-0.9	-1.1	-0.5	-0.7	-0.5	-0.1	-0.3	0.6	-0.6	0.1	-0.4	-0.5	-0.9
Hypothyroidism (self reported)	1.3	2.9	7.6	0.5	2.4	-1.8	0.8	2.0	1.7	-0.3	-1.3	0.4	1.7	1.0	2.4	-2.0	1.6	-1.5	1.6	2.8	2.0
Respiratory disease	0.3	0.7	2.2	-1.3	-1.0	1.2	-0.9	-0.1	-0.2	-0.9	0.0	-0.9	-0.9	-0.2	-0.0	1.5	-0.1	-1.2	-0.6	-0.5	-0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.1	-0.7	1.0	-1.1	-0.4	0.1	-0.0	-0.8	-0.9	-0.3	-0.6	0.1	0.5	-0.2	0.1	-1.0	-0.1	0.1	-0.4
Lung FEV1/FVC ratio	2.3	11.9	35.3	5.0	1.9	-2.0	3.0	2.9	3.2	4.4	5.9	3.0	3.7	3.6	2.2	-2.2	3.1	3.5	3.0	3.1	3.9
Lung FVC	0.4	1.9	17.5	-1.1	0.2	-1.2	-0.4	-0.6	-0.6	-1.0	-4.2	-0.6	-0.1	0.2	-0.4	-1.6	-0.7	-1.5	-1.0	-1.0	-1.8
Neuroticism	0.2	0.4	2.6	0.0	-0.6	-0.7	0.3	-0.7	-0.7	-0.0	1.0	0.2	-0.2	-0.0	-0.7	0.7	-0.7	1.6	0.3	0.4	-0.1
Chronotype (morning person)	2.2	5.0	21.4	-2.0	-0.4	1.2	-3.4	-1.2	-1.4	-3.5	-2.7	-3.2	-0.3	-2.9	-0.8	-1.0	-1.7	-4.6	-2.2	0.2	-0.1
Hair Pigment	0.3	7.4	11.4	-2.8	-2.6	1.8	-2.2	-2.9	-2.9	-2.9	-3.0	-2.1	-3.4	-2.8	-2.7	3.0	-3.1	-1.5	-2.7	-2.5	-3.3
Tanning	0.1	1.6	4.8	2.2	0.6	-1.9	1.6	1.1	1.2	1.5	0.1	1.8	0.5	2.2	0.8	-1.0	0.9	0.9	1.0	0.6	0.6
Hand grip strength (left)	4.0	10.7	25.7	-3.0	-4.5	3.2	-2.5	-3.1	-2.9	-3.0	-2.3	-2.3	-3.8	-3.0	-3.3	5.1	-3.2	-0.9	-3.2	-3.5	-3.8
Number of treatments/medications taken	0.4	0.8	5.8	-0.6	0.9	-2.4	1.5	0.6	0.4	0.2	-1.0	0.6	0.0	-0.2	0.9	0.4	0.6	0.5	1.0	0.6	-0.2
Average weekly spirits intake	0.4	0.4	2.3	-0.9	-0.5	1.0	0.0	0.0	-0.0	-0.7	-0.6	-0.2	-1.4	0.2	0.1	1.5	-0.2	-0.7	-0.1	0.2	-0.2
Sensitivity / hurt feelings	0.3	0.5	2.3	0.5	1.0	-1.5	0.5	0.4	0.5	0.2	0.4	0.3	0.9	0.7	0.3	-1.2	0.2	-0.1	0.4	1.3	0.8
Frequency of depressed mood in last 2 weeks	3.8	5.3	13.9	1.4	1.2	-1.5	3.4	1.9	1.9	2.8	1.5	3.5	1.2	3.7	1.9	0.5	2.2	3.5	2.9	1.4	1.4
Hearing difficulty/problems: Yes	1.0	1.5	5.6	0.7	1.9	-0.9	0.7	1.2	1.2	0.8	-0.1	0.5	2.1	1.0	1.2	-2.4	1.1	-0.4	0.9	1.1	1.2
Relative age of first facial hair	0.2	0.4	1.2	0.4	-0.0	-0.0	0.7	0.9	1.0	0.0	-1.1	0.6	-0.1	0.0	0.8	0.8	0.7	-0.5	0.4	0.2	-0.0
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.9	0.3	0.5	-0.8	0.6	0.3	0.3	0.4	0.9	0.0	0.4	-0.1	0.3	-0.4	0.4	0.2	0.5	0.7	0.6
Ever used hormone-replacement therapy (HRT)	0.4	0.4	2.2	0.3	-0.5	-1.2	1.0	-0.0	0.0	0.6	1.0	0.7	-0.2	0.5	0.0	0.8	0.1	1.5	0.6	0.2	0.0
Ever had hysterectomy (womb removed)	0.4	0.5	3.2	-0.3	-1.1	-0.1	0.8	-0.3	-0.1	0.2	0.7	0.5	-0.8	0.1	-0.5	1.8	-0.3	0.7	-0.1	-0.5	-0.7
Systolic blood pressure, automated reading	1.0	2.8	6.3	-2.5	-1.3	0.8	-1.8	-1.9	-2.1	-1.3	-0.3	-1.7	-1.7	-1.3	-1.6	2.2	-1.5	-0.1	-1.5	-2.3	-2.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.2	-0.2	-0.1	-0.3	-0.5	-0.5	-0.5	0.1	-0.6	-0.5	0.1	-0.5	0.3	-0.5	-0.6	-0.5	-0.2	-0.4
Angina	0.8	1.0	3.6	1.3	0.9	-1.2	0.7	1.3	1.4	0.8	-0.1	0.6	0.6	0.7	1.0	-1.9	1.1	-0.5	0.5	1.2	1.1
Medication for hormone replacement therapy	0.2	0.3	0.7	0.7	0.2	0.3	0.6	0.4	0.4	0.8	0.8	0.6	0.3	0.5	0.4	-0.1	0.6	0.7	0.6	0.0	0.3
Vitamin and mineral supplements	2.3	3.1	9.6	-0.9	-2.9	2.5	-1.4	-1.9	-1.8	-1.2	0.2	-1.1	-1.6	-2.4	-1.8	3.1	-1.7	0.5	-1.2	-1.4	-1.3
Supplements: Zinc	0.8	0.9	2.9	0.2	0.4	-0.7	1.7	0.8	0.8	1.2	0.1	1.7	-0.3	1.1	0.8	1.1	0.9	1.4	1.1	0.3	0.1
Medication: Co-codamol	0.6	0.7	3.1	0.3	-1.0	-1.7	0.6	-0.3	-0.1	0.3	0.0	0.5	-1.8	-0.5	-0.5	1.4	-0.2	0.3	-0.4	-1.0	-1.3
Medication: Metformin	0.6	0.8	4.5	-0.7	1.3	-0.7	-0.7	0.0	-0.2	-1.4	-1.3	-1.2	-0.0	0.1	0.4	-0.8	-0.2	-2.1	-0.2	0.8	0.2
Diabetes (father)	0.7	0.8	2.0	-1.4	0.2	0.3	-0.6	-1.1	-1.2	-1.2	-1.0	-1.1	-0.8	-1.3	-0.7	0.2	-1.0	-0.9	-0.7	-0.2	-0.9
Diabetes (mother)	0.4	0.6	2.6	-0.6	-1.1	0.8	0.3	-0.7	-0.8	-0.5	-0.5	-0.2	-1.4	-0.4	-0.6	1.6	-0.7	0.1	-0.2	-0.2	-0.7
Severe depression (siblings)	2.4	2.7	6.6	1.0	1.5	-1.7	2.6	1.5	1.4	1.8	0.2	2.1	1.7	0.6	1.6	-0.8	1.4	1.6	2.2	2.2	1.6
Pack years adult smoking proportion	0.3	0.4	2.3	0.2	0.9	-0.9	-0.5	-0.0	-0.0	-0.5	0.2	-0.9	0.8	-0.0	0.1	-1.5	-0.2	-1.0	-0.1	0.6	0.6
Impedance of leg (right)	0.1	0.4	2.9	-0.5	0.4	-0.5	0.5	0.1	-0.0	-0.8	-1.7	0.2	-0.2	0.1	0.3	0.5	-0.2	-1.1	0.1	0.4	-0.5
Leg fat-free mass (left)	0.1	0.8	4.6	0.2	-1.1	-0.9	0.3	-0.5	-0.5	0.6	1.8	0.1	-0.4	-0.8	-0.5	1.2	-0.1	2.1	0.5	0.1	0.4
Trunk fat percentage	0.8	3.3	7.3	1.7	1.8	-2.2	2.5	1.6	1.6	2.7	1.9	2.0	0.9	1.9	1.7	-1.0	2.1	2.0	2.0	1.1	1.2
Hand grip strength (right)	3.9	10.7	24.0	-2.4	-4.9	3.2	-3.1	-3.3	-3.0	-3.2	-1.4	-2.8	-3.4	-3.1	-3.6	4.6	-3.4	-1.3	-3.5	-3.3	-3.3
Townsend deprivation index at recruitment	1.8	2.6	5.7	-1.1	-1.9	0.3	-0.8	-1.6	-1.5	-1.5	-1.9	-0.7	-2.4	-0.9	-1.8	2.2	-1.9	-0.8	-1.7	-1.7	-2.3
Current tobacco smoking	0.3	0.4	3.2	0.7	0.7	-1.8	0.3	0.2	0.2	0.3	-0.6	-0.0	0.4	0.8	0.2	-1.2	0.1	-0.8	-0.1	0.1	-0.1
Average weekly fortified wine intake	0.3	0.4	2.2	0.5	-0.4	0.8	-0.8	0.1	0.2	-0.5	-0.5	-0.5	-1.1	0.1	-0.0	-0.2	0.0	-1.5	-0.9	-0.2	-0.3
Maternal smoking around birth	4.5	6.5	10.4	3.2	1.7	-2.6	3.1	2.7	2.8	2.7	1.9	3.0	2.3	2.3	2.5	-1.0	2.6	2.3	3.0	2.6	2.5
Fed-up feelings	2.7	4.9	13.1	1.7	0.8	-2.0	3.2	1.9	1.9	2.9	1.7	3.2	0.9	2.7	1.7	0.5	2.1	3.6	2.9	1.7	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.2	9.8	1.0	0.6	-0.9	3.1	1.4	1.5	2.5	1.0	2.9	1.0	2.2	1.3	0.5	1.6	3.1	2.3	0.8	0.8
Relative age voice broke	1.1	1.8	3.1	1.5	1.7	-0.5	0.8	1.7	1.7	1.2	0.2	1.3	1.3	1.8	1.7	-1.6	1.7	-0.0	1.2	0.9	1.2
Taking other prescription medications	0.5	0.7	3.2	-0.5	1.3	-1.8	1.0	0.6	0.4	0.2	0.1	0.6	0.9	-0.1	1.0	-0.1	0.7	0.6	1.2	1.0	0.7
Age when periods started (menarche)	0.3	0.6	1.9	0.5	0.9	0.6	-1.1	0.7	0.7	0.4	1.1	-0.4	1.4	0.1	0.7	-1.2	0.8	-1.1	-0.3	-0.3	0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.4	0.3	-0.4	-1.0	0.7	-0.1	-0.1	0.8	1.6	0.3	-0.4	0.6	0.0	0.7	0.2	0.9	0.4	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.1	-0.6	-0.5	0.8	-0.1	-0.9	-0.8	-0.8	-0.6	-0.4	-0.6	-0.6	-0.8	0.6	-1.1	-0.4	-0.5	-0.3	-0.7
Tinnitus: Yes, but not now, but have in the past	4.1	4.4	9.5	2.2	1.6	-3.1	2.7	1.8	1.8	2.4	1.3	2.6	2.1	1.4	1.7	-1.0	1.9	2.7	2.4	2.0	1.7
Qualifications: CSEs or equivalent	0.4	0.6	2.1	0.5	1.3	-0.6	-0.4	0.5	0.6	0.4	1.5	-0.1	0.5	0.8	0.6	-1.5	0.7	-0.5	0.1	-0.1	0.7
Serious illness, injury or assault to yourself	0.3	0.3	1.2	0.1	-0.3	-1.1	0.8	-0.1	-0.0	0.6	0.9	0.4	-0.4	-0.0	-0.2	0.9	0.1	0.9	0.3	-0.3	-0.2
High blood pressure	0.1	0.4	2.3	-1.5	0.7	-0.1	-0.9	-0.4	-0.7	-1.0	-0.5	-0.8	0.2	-0.2	-0.1	-0.2	-0.4	-0.1	-0.2	-0.1	-0.3
Hayfever, allergic rhinitis or eczema	1.6	3.4	5.8	-2.0	-1.8	0.7	-1.5	-2.0	-2.1	-2.4	-1.5	-1.9	-2.0	-1.6	-1.8	2.4	-2.2	-1.1	-1.7	-1.7	-2.2
Multivitamins +/- minerals	2.6	3.3	7.4	1.7	2.4	-2.5	1.4	2.0	2.1	1.7	1.2	1.3	1.6	2.2	1.8	-2.7	2.0	-0.2	1.3	1.2	1.5
Stomach or abdominal pain in last month	0.8	1.1	4.5	0.2	0.6	-0.9	1.4	0.7	0.6	1.1	0.5	1.7	0.5	0.9	0.8	0.8	0.8	2.1	1.5	0.6	0.4
Supplements: Glucosamine	2.0	2.6	5.0	1.5	1.8	-0.4	1.2	1.9	1.9	1.0	0.3	1.1	1.6	1.8	2.0	-2.2	1.7	-0.3	1.6	2.1	2.2
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.6	0.1	0.6	-0.2	0.9	0.5	0.4	0.8	1.6	1.0	0.6	1.1	0.7	0.5	0.6	1.6	1.2	0.9	0.9
Medication: Atenolol	0.5	0.6	1.4	1.0	0.3	-0.9	0.9	1.0	1.1	0.7	-0.2	1.2	0.3	0.7	0.9	-0.2	0.9	0.9	0.9	0.7	0.6
Medication: Levothyroxine sodium	1.1	1.8	5.0	0.2	2.2	-0.9	0.4	1.3	1.0	0.3	0.2	-0.2	2.1	0.6	1.7	-2.2	1.3	-0.7	1.3	1.8	1.8
Sitting height	0.3	2.3	17.8	-1.2	-2.4	-0.2	0.6	-0.6	-0.9	-1.3	-2.1	0.4	-1.8	-1.4	-0.3	4.2	-0.7	1.6	0.5	0.3	-0.8
Chronic bronchitis/emphysema (father)	1.0	1.2	3.5	-1.1	-0.6	-0.0	-0.6	-1.0	-1.0	-0.8	-1.3	-1.2	-1.5	-1.9	-1.1	0.2	-0.9	-1.1	-1.3	-1.2	-1.5
High blood pressure (mother)	0.6	0.9	5.1	-0.0	-0.5	-0.5	0.7	0.3	0.3	0.7	1.6	0.9	0.2	0.6	0.4	1.9	0.6	2.3	1.0	-0.1	0.2
Body mass index (BMI)	0.6	2.8	9.2	1.7	1.0	-2.0	1.9	0.9	1.0	2.8	2.8	2.0	0.4	1.6	0.7	-0.5	1.5	3.0	1.4	0.0	0.5
Impedance of leg (left)	0.1	0.5	3.9	-0.8	0.6	-0.4	0.2	0.1	-0.1	-1.1	-2.0	-0.1	-0.2	0.2	0.3	0.1	-0.2	-1.5	-0.2	0.3	-0.6
Leg predicted mass (left)	0.2	0.8	4.9	0.2	-1.1	-1.0	0.3	-0.5	-0.5	0.7	1.8	0.1	-0.4	-0.8	-0.5	1.2	-0.1	2.2	0.5	0.1	0.4
Trunk fat mass	0.5	2.2	5.2	1.2	1.1	-2.2	2.0	1.0	0.9	2.2	1.9	1.6	0.4	1.3	1.1	-0.2	1.5	2.3	1.7	0.7	0.8
Waist circumference	0.8	2.9	7.1	1.3	2.1	-2.7	2.1	1.3	1.2	2.4	1.7	1.8	1.0	1.5	1.5	-1.1	1.8	2.1	1.9	1.0	1.0
Number of incorrect matches in round	0.6	1.0	8.0	-1.7	0.1	0.6	-0.5	-0.0	-0.2	-1.6	-2.8	-0.0	-0.7	0.6	0.3	0.8	-0.4	-1.1	-0.3	-0.0	-1.0
Past tobacco smoking	3.3	6.1	14.7	3.1	0.8	-0.5	2.6	2.2	2.5	3.7	2.9	3.4	1.2	3.5	1.8	-0.5	2.6	3.8	2.5	1.0	1.8
Alcohol usually taken with meals	0.2	0.2	1.1	-0.9	-0.5	0.9	-0.2	-0.2	-0.3	-0.6	0.0	0.1	-0.3	-0.6	-0.0	1.0	-0.3	0.6	0.3	0.1	0.2
Nervous feelings	0.8	1.6	4.5	-1.6	-1.4	0.1	-0.3	-1.4	-1.4	-1.1	-1.1	-0.8	-2.1	0.0	-1.4	2.0	-1.4	-0.0	-0.9	-1.0	-1.6
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.5	4.5	0.7	1.7	-1.4	1.9	1.4	1.2	1.6	1.3	1.8	1.8	1.8	1.5	-0.8	1.6	1.5	2.1	1.8	1.9
Hearing difficulty/problems with background noise	0.2	0.4	2.1	-0.1	0.3	1.3	-0.4	0.2	0.3	-0.6	-0.8	-0.5	0.5	0.1	0.1	-0.9	-0.1	-1.4	-0.4	0.6	0.3
Hair/balding pattern: Pattern 2	0.3	0.4	1.3	-0.4	0.8	-0.6	-0.2	-0.1	-0.2	-0.1	0.9	-0.3	1.0	0.8	0.2	-1.1	-0.0	0.5	0.6	0.6	1.1
Had menopause	0.1	0.2	1.4	-0.6	-0.2	0.5	-0.4	-0.2	-0.3	-0.2	1.2	-0.4	-0.0	-0.2	0.0	0.5	0.1	0.5	0.2	-0.1	0.4
Had other major operations	2.6	3.2	6.5	1.9	1.1	-0.8	1.7	2.0	1.9	1.6	2.1	1.5	2.0	0.6	2.2	-0.6	2.1	1.3	2.4	2.2	2.5
Forced vital capacity (FVC)	1.1	4.1	7.5	-2.1	-1.8	0.8	-2.4	-2.1	-2.1	-2.7	-2.6	-2.5	-1.5	-2.2	-1.9	0.7	-2.2	-2.0	-2.3	-1.3	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.7	-0.3	-0.2	0.8	-0.1	-0.5	-0.5	-0.7	-0.3	-0.2	-0.3	-0.6	-0.5	0.5	-0.8	-0.6	-0.3	0.0	-0.3
Ever unenthusiastic/disinterested for a whole week	1.7	2.0	12.0	1.7	-0.2	-3.5	1.9	0.5	0.8	1.7	1.6	1.8	0.3	1.0	0.1	0.5	0.6	2.2	1.0	0.6	0.4
Qualifications: None of the above	0.6	1.4	3.4	-1.0	-1.0	1.1	-0.7	-1.5	-1.5	-0.8	-0.6	-0.9	-1.3	-0.8	-1.5	0.6	-1.5	0.1	-1.2	-1.5	-1.8
Financial difficulties in last 2 years	0.5	0.7	6.6	0.0	0.5	-1.3	0.5	0.0	0.0	1.2	2.6	0.6	0.4	-0.2	-0.0	0.4	0.5	1.2	0.3	-0.3	0.1
Mouth/teeth dental problems	0.5	0.8	1.7	1.0	-0.1	0.3	1.1	0.8	0.9	1.1	1.2	1.3	-0.1	1.1	0.6	0.5	0.8	1.3	0.9	0.3	0.6
Heart attack	0.4	0.5	4.3	0.4	0.7	-2.1	0.8	0.3	0.2	0.3	-0.5	0.7	0.7	-0.5	0.3	-0.7	0.2	0.9	0.6	0.7	0.2
Allergy	0.6	1.3	3.0	1.7	1.1	-0.3	0.7	1.1	1.2	1.3	0.8	0.9	1.2	0.7	1.1	-1.7	1.3	0.5	1.0	1.5	1.6
Pain all over the body in last month	0.2	0.2	1.2	-0.1	0.2	-0.3	0.2	-0.5	-0.5	0.3	0.2	0.2	-0.2	-1.0	-0.5	-0.2	-0.5	1.1	0.0	-0.6	-0.5
Diabetes (self-reported)	0.2	0.3	1.2	-0.3	0.6	-0.9	-0.5	-0.1	-0.2	-0.9	-0.8	-0.4	-0.5	-0.2	0.1	-0.2	-0.2	-1.1	-0.3	0.2	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	1.2	-0.7	0.4	-0.3	0.1	-0.1	-0.3	-0.5	-0.1	0.1	-0.4	0.6	0.2	1.1	-0.1	0.5	0.4	-0.1	-0.2
Medication: Ramipril	1.1	1.4	2.7	0.5	1.4	-1.6	1.0	1.4	1.4	1.0	0.6	1.2	1.4	1.4	1.4	-1.0	1.4	0.9	1.2	1.2	1.0
Medication: Simvastatin	0.1	0.2	1.1	-0.3	0.5	-1.0	0.1	0.1	0.0	-0.1	-0.7	-0.0	-0.3	-0.5	0.2	-0.5	0.1	0.1	0.0	-0.3	-0.6
Fluid intelligence score	1.0	2.1	4.8	1.7	1.0	-2.2	1.6	1.6	1.7	1.5	0.6	1.6	1.7	1.1	1.4	-0.9	1.5	1.1	1.5	1.4	1.6
Illnesses of siblings	0.6	0.8	3.4	0.4	-0.3	1.8	-1.5	-0.5	-0.4	-0.8	0.1	-1.3	0.3	-1.0	-0.6	-0.6	-0.6	-1.6	-1.0	-0.1	0.2
Neuroticism score	0.2	0.5	2.9	-0.1	-0.7	-0.6	0.6	-0.6	-0.6	0.1	0.9	0.5	-0.5	0.4	-0.6	1.2	-0.5	1.7	0.4	0.4	-0.0
Weight	0.3	1.5	9.0	0.7	-0.5	-1.9	1.4	-0.1	-0.1	1.6	2.0	1.1	-0.6	0.3	-0.1	1.4	0.5	3.0	1.0	-0.2	-0.0
Impedance of arm (right)	0.2	0.8	2.0	0.5	0.8	0.2	1.4	1.2	1.1	0.3	-0.9	0.9	0.5	0.7	1.4	0.0	0.9	-0.5	1.2	1.3	0.9
Arm fat percentage (right)	1.4	5.4	13.1	2.4	1.9	-2.3	3.0	1.8	1.9	3.6	2.9	2.9	1.0	2.4	1.7	-0.8	2.4	3.4	2.4	0.9	1.3
Trunk fat-free mass	0.3	1.6	6.6	-0.3	-2.2	-0.7	-0.1	-1.2	-1.2	0.0	1.5	-0.1	-1.1	-1.0	-1.2	2.5	-0.8	2.6	0.0	-0.5	-0.3
Hip circumference	0.4	1.8	9.9	0.4	-0.0	-1.8	1.7	0.2	0.1	2.0	2.0	1.5	-0.6	1.2	0.3	1.4	0.9	3.1	1.2	-0.4	-0.1
Time employed in main current job	0.7	0.8	2.5	-1.6	-0.3	-0.5	-0.4	-0.5	-0.5	-0.4	-1.3	-0.6	-1.4	-0.7	-0.5	0.7	-0.3	-0.7	-0.8	-1.5	-1.3
Alcohol intake versus 10 years previously	0.4	0.6	1.9	-1.1	0.0	-1.4	-0.7	-0.7	-0.8	-0.7	-0.2	-1.2	-0.3	-0.1	-0.5	-0.4	-0.6	-1.2	-0.9	-0.4	-0.8
Father’s age at death	1.7	2.2	3.6	-1.6	-1.5	1.5	-1.4	-1.9	-1.8	-1.8	-0.5	-1.9	-1.8	-1.6	-1.8	1.0	-1.9	-0.7	-1.4	-0.8	-1.0
Worrier / anxious feelings	0.1	0.2	1.2	-0.6	0.5	-0.1	-0.8	-0.3	-0.5	-0.1	0.5	-0.7	0.3	0.7	-0.1	-1.1	-0.1	-0.0	-0.1	0.2	0.5
Frequency of tiredness / lethargy in last 2 weeks	5.4	8.8	16.9	2.6	2.2	-2.4	3.5	2.8	2.7	3.8	2.7	4.0	2.1	3.6	2.8	-0.7	3.2	4.1	3.7	1.9	2.4
Falls in the last year	1.3	1.8	4.5	1.8	1.3	-1.6	1.9	1.1	1.2	2.1	1.3	1.6	0.8	0.5	0.8	-1.1	1.2	1.4	1.3	0.9	1.0
Hair/balding pattern: Pattern 3	1.3	1.9	4.5	1.8	1.4	-0.3	0.9	2.0	2.1	1.1	0.3	1.0	1.6	0.5	1.6	-1.6	1.7	-0.7	0.9	1.7	1.5
Number of live births	2.5	3.6	9.9	2.0	1.9	-0.1	1.6	1.7	1.6	2.0	3.1	1.6	2.1	1.7	1.7	-1.1	1.7	1.9	2.2	2.0	2.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.3	-0.5	-0.8	-0.4	-1.1	-1.0	-0.9	-1.1	-0.6	-1.1	-0.2	-1.0	-1.0	-0.0	-1.1	-0.6	-1.1	-0.3	-0.7
Pulse rate	0.7	1.2	5.2	-2.3	0.6	-0.6	-1.2	-1.2	-1.4	-1.0	-1.1	-1.3	-0.1	-1.3	-0.8	-1.0	-0.9	-0.6	-0.8	-0.9	-1.0
Happiness	0.8	0.9	5.5	-0.3	-1.0	1.3	0.6	0.2	0.2	0.7	1.2	1.1	-0.6	0.7	0.1	2.4	0.2	1.8	0.7	-0.2	0.3
Noisy workplace	0.6	0.7	1.9	1.4	0.9	-0.4	0.6	1.2	1.2	0.4	-0.5	0.4	1.0	0.2	1.1	-1.0	1.1	-0.7	0.4	0.9	0.5
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.7	1.4	0.2	0.0	1.3	1.5	1.6	0.9	0.8	1.3	1.3	0.5	1.5	0.1	1.3	0.6	1.6	1.6	1.9
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	2.3	0.3	-0.6	0.1	0.2	0.1	0.2	0.3	1.5	-0.1	-0.4	0.3	-0.1	0.8	0.3	0.4	0.0	0.1	0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	1.3	0.6	-0.2	-1.1	0.7	0.1	0.2	0.2	-0.6	0.2	0.4	-0.0	0.1	-0.0	0.1	-0.0	0.2	0.2	-0.1
Asthma	0.1	0.3	1.1	-0.8	-0.5	1.1	-0.7	0.1	-0.0	-0.7	0.3	-1.0	0.1	-0.0	0.1	0.4	0.1	-0.9	-0.2	0.1	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.3	1.2	0.7	-0.8	1.2	0.7	0.8	0.8	0.8	0.9	1.5	-0.2	0.7	-1.0	0.6	1.2	1.1	1.2	1.1
Medication: Cholesterol lowering	0.3	0.4	1.7	-0.6	0.1	-1.3	-0.6	-0.6	-0.7	-0.9	-0.8	-0.7	-0.3	-1.0	-0.4	-0.3	-0.6	-0.3	-0.5	-0.3	-0.6
Depression (self-reported)	0.2	0.2	1.5	-0.2	0.4	-1.2	0.5	-0.2	-0.3	-0.3	-0.8	0.1	-0.7	-0.3	-0.1	0.0	-0.3	-0.3	0.2	0.8	0.0
Medication: Lansoprazole	1.0	1.1	3.0	0.7	1.4	-1.7	1.5	0.8	0.7	0.9	-0.3	1.2	0.8	1.2	1.1	-0.8	0.8	0.8	1.4	1.0	0.6
Prospective memory result	0.7	0.8	2.3	0.9	0.9	0.7	0.6	1.2	1.2	0.7	0.1	0.5	0.4	1.1	1.1	-1.5	1.0	-0.4	0.6	1.3	1.1
Lung cancer (father)	0.9	1.0	4.3	1.2	-0.1	-1.8	1.0	0.2	0.4	1.2	2.1	1.1	1.1	0.1	-0.1	-0.3	0.2	1.9	0.7	0.3	0.4
Illnesses of mother	0.5	0.7	3.4	1.5	0.8	0.2	0.6	0.8	0.9	0.8	0.1	0.4	0.8	0.4	0.4	-1.8	0.6	-0.5	0.2	0.9	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.6	0.0	-0.8	-0.4	-0.3	-0.6	-0.5	-0.7	-0.7	-0.4	-0.5	-0.1	-0.7	0.5	-0.8	-0.0	-0.6	0.1	-0.4
Pulse wave Arterial Stiffness index	0.4	0.4	1.7	-0.7	1.3	-0.9	0.0	0.3	0.2	-0.4	-0.7	-0.4	0.8	0.1	0.5	-1.1	0.2	-0.8	0.2	0.8	0.4
Impedance of arm (left)	0.2	1.0	2.4	0.4	1.1	0.4	1.1	1.3	1.1	-0.1	-1.5	0.7	0.7	0.6	1.6	-0.4	0.9	-1.1	1.1	1.5	0.9
Arm fat mass (right)	0.8	3.5	11.3	2.0	0.9	-2.2	2.4	1.1	1.2	3.0	2.8	2.2	0.4	1.7	1.0	-0.1	1.7	3.4	1.9	0.5	0.9
Trunk predicted mass	0.3	1.6	7.0	-0.3	-2.3	-0.8	-0.0	-1.1	-1.1	0.1	1.6	-0.0	-1.1	-1.0	-1.1	2.6	-0.8	2.6	0.1	-0.5	-0.3
Standing height	0.5	4.9	18.9	-2.3	-3.5	0.2	-1.2	-2.3	-2.5	-2.6	-1.3	-1.8	-2.4	-3.0	-1.9	4.3	-2.3	0.2	-1.0	-0.6	-1.4
Length of working week for main job	2.0	2.2	3.6	1.6	1.3	-1.1	1.2	1.8	1.9	1.8	1.5	1.7	1.6	0.8	1.8	-1.3	1.9	1.0	1.5	1.0	1.5
Exposure to tobacco smoke at home	0.4	0.4	1.1	-0.8	0.4	-0.2	-1.0	-0.7	-0.7	-0.7	0.0	-0.8	-0.4	-0.6	-0.6	-0.3	-0.5	-0.4	-0.8	-0.8	-0.7
Breastfed as a baby	0.2	0.2	1.3	0.6	-0.6	1.1	-0.2	-0.0	0.1	0.2	0.2	0.2	-0.8	-0.7	-0.3	0.4	0.0	0.0	-0.3	-0.4	-0.1
Tense / ‘highly strung’	0.6	1.0	2.4	-1.3	-1.1	0.7	-0.3	-1.1	-1.2	-1.6	-1.3	-0.9	-1.2	-0.5	-1.1	1.0	-1.4	-0.6	-0.6	0.1	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	6.1	0.6	-0.6	-2.5	0.8	-0.3	-0.1	0.1	-0.0	0.6	0.1	-0.6	-0.6	0.4	-0.5	1.0	0.1	0.4	-0.1
Hair/balding pattern: Pattern 4	0.1	0.2	1.1	-0.2	0.2	-1.1	0.2	-0.0	-0.1	-0.3	-0.3	-0.3	0.3	-0.3	0.2	-0.5	-0.1	-0.2	0.3	0.8	0.5
Birth weight of first child	1.1	2.0	11.6	0.0	-2.8	1.6	0.3	-0.9	-0.6	0.4	1.6	0.0	-1.8	0.4	-1.4	3.4	-0.6	1.0	-0.8	-1.5	-1.1
Peak expiratory flow (PEF)	1.1	2.5	5.9	-1.8	-1.0	0.4	-1.8	-1.4	-1.5	-2.4	-1.5	-2.0	-1.3	-2.1	-1.3	1.0	-1.7	-2.0	-1.8	-0.6	-1.3
Pulse wave reflection index	1.9	2.4	6.0	1.5	2.4	-1.6	1.9	1.7	1.7	1.4	-0.5	1.4	1.4	1.4	1.6	-2.0	1.4	0.1	1.4	1.6	1.2
Ever highly irritable/argumentative for 2 days	1.2	1.5	6.1	1.4	0.0	-0.4	1.2	0.7	0.7	2.0	2.0	1.8	0.2	0.6	0.7	1.0	1.1	2.5	1.2	0.1	0.4
Loud music exposure frequency	0.9	0.9	1.8	-1.0	-0.4	0.0	-1.2	-1.2	-1.2	-1.0	0.5	-1.3	-0.8	-1.1	-1.3	0.2	-1.2	-0.8	-1.3	-0.8	-0.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.7	1.0	0.3	-0.9	0.7	1.0	1.0	0.2	0.0	0.2	0.9	-0.2	0.9	-0.6	0.7	-0.5	0.8	1.6	1.5
Mouth/teeth dental problems: Bleeding gums	1.7	2.3	5.4	-1.7	-0.2	1.2	-2.3	-1.5	-1.6	-2.1	-1.6	-2.3	-0.9	-0.9	-1.1	-0.4	-1.5	-2.1	-1.7	-0.5	-0.9
Blood clot in the leg (DVT)	3.3	4.3	11.6	1.2	2.7	-3.4	2.4	2.0	2.0	1.8	-0.3	2.3	2.3	2.3	1.8	-2.7	1.7	1.2	2.0	1.7	1.4
Medication: Paracetamol	0.2	0.3	2.5	-0.4	-0.4	-1.6	-0.3	-0.4	-0.3	-0.1	-0.1	-0.5	0.2	-0.9	-0.5	0.3	-0.3	-0.3	-0.6	-0.6	-0.6
Headache pain in last month	1.1	1.9	4.3	1.0	0.5	-1.7	1.9	1.4	1.3	1.4	0.3	1.8	1.4	2.1	1.4	0.4	1.5	1.6	1.7	1.3	1.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.0	1.4	-0.1	0.2	0.9	0.7	0.8	1.1	1.0	0.8	0.6	1.2	0.4	-0.4	0.6	0.3	0.6	0.6	0.9
Glaucoma (self-reported)	0.6	0.8	4.0	-0.3	-1.2	2.0	-0.6	-0.8	-0.8	0.1	1.7	-0.4	-0.4	-0.5	-0.9	0.9	-0.5	0.9	-0.3	-0.4	-0.1
Gout (self-reported)	0.3	0.4	2.8	0.1	0.3	-0.4	-0.2	0.1	0.2	-0.6	-1.7	-0.2	-0.8	-0.2	-0.0	-0.9	-0.2	-1.4	-0.7	-0.1	-0.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.4	0.2	1.8	-1.0	0.5	1.3	1.1	-0.0	-0.0	-0.0	1.6	0.6	1.6	-1.4	1.2	-1.0	1.1	1.8	1.6
Medication: Amlodipine	0.6	0.8	3.1	0.7	0.7	0.6	-0.1	0.9	0.8	0.5	1.8	-0.1	1.2	0.9	0.9	-1.1	1.0	-0.2	0.6	1.0	1.5
Medication: Ventolin 100micrograms inhaler	1.7	2.2	4.5	-0.9	-2.1	1.4	-2.0	-1.4	-1.3	-1.4	0.6	-2.0	-1.2	-1.3	-1.6	1.6	-1.3	-1.3	-1.9	-1.3	-1.1
Birth weight	0.5	1.1	3.3	0.5	-1.5	1.8	-1.4	-0.1	-0.1	-1.0	0.6	-1.6	0.4	-1.6	-0.2	0.3	-0.2	-1.8	-0.8	0.8	0.9
Chronic bronchitis/emphysema (mother)	0.4	0.5	3.6	0.2	0.8	-1.9	1.1	0.4	0.4	0.8	-0.2	0.8	0.1	0.3	0.5	-0.1	0.6	0.3	0.4	-0.4	-0.8
High blood pressure (siblings)	1.0	1.5	7.6	-0.2	-1.2	-1.2	1.4	0.1	0.1	1.0	1.1	1.3	-1.3	0.0	0.1	2.8	0.4	2.5	0.8	-0.6	-0.6
Forced vital capacity (FVC), Best measure	0.6	2.0	6.4	-1.4	-1.5	0.4	-1.1	-1.4	-1.4	-1.9	-2.5	-1.3	-1.5	-1.0	-1.3	1.4	-1.6	-1.0	-1.3	-0.7	-1.5
Body fat percentage	0.9	3.5	7.8	1.8	2.0	-2.4	2.5	1.5	1.5	2.8	2.0	2.2	0.9	1.9	1.6	-1.1	2.0	2.2	2.0	1.0	1.0
Leg fat percentage (right)	0.7	2.6	7.5	1.4	1.4	-2.7	2.2	0.9	1.0	2.5	1.9	2.1	0.4	1.7	0.8	-0.5	1.4	2.5	1.4	0.3	0.3
Arm fat-free mass (right)	0.2	1.0	3.2	-0.6	-1.5	-0.6	-0.6	-1.1	-1.2	-0.1	1.4	-0.5	-1.0	-1.0	-1.0	1.6	-0.7	1.8	-0.2	-0.7	-0.4
Exposure to tobacco smoke outside home	0.2	0.3	1.5	-0.1	1.2	0.6	-0.4	-0.1	-0.2	0.5	1.1	-0.4	0.1	-0.4	-0.0	-1.2	0.3	-0.4	-0.2	-0.5	0.1
Comparative body size at age 10	2.4	6.6	19.0	2.4	2.9	-4.4	2.3	2.8	2.7	2.2	0.6	2.3	2.5	2.9	2.7	-2.8	2.6	1.0	2.5	2.6	2.4
Number of full brothers	3.2	4.1	8.6	2.5	1.2	-1.6	2.2	2.3	2.4	2.4	1.5	2.3	1.3	2.9	2.2	-1.1	2.4	1.3	2.1	1.5	1.8
Worry too long after embarrassment	0.6	1.0	2.3	-0.8	-1.0	0.2	-0.9	-1.5	-1.5	-0.8	0.6	-0.9	-0.9	-0.1	-1.5	1.0	-1.3	-0.0	-1.0	-1.1	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.4	0.3	-0.4	-0.4	-0.0	-0.2	-0.1	-0.5	0.2	-0.3	0.2	-0.6	-0.3	-0.3	-0.5	-0.7	-0.1	0.6	0.5
Wheeze or whistling in the chest in last year	1.0	1.7	5.4	1.7	1.1	-2.3	1.5	1.5	1.6	1.1	0.3	1.4	1.4	1.0	1.3	-0.8	1.3	0.4	1.2	1.3	1.0
Number of children fathered	1.5	1.7	7.5	-0.7	-0.9	2.7	-1.6	-1.4	-1.4	-0.8	1.3	-1.4	-1.0	-1.6	-1.2	1.1	-1.0	-0.3	-1.3	-1.3	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	3.3	-0.9	-0.6	0.2	-0.9	-0.9	-0.9	-1.5	-1.8	-1.1	-1.1	-0.5	-0.8	0.1	-1.0	-1.5	-1.1	-0.6	-1.1
Age at first live birth	0.1	0.2	0.9	0.9	-0.1	0.4	-0.3	0.7	0.8	0.2	-0.1	0.2	0.6	0.4	0.5	-0.4	0.6	-0.4	-0.1	0.1	0.3
Pulse wave peak to peak time	0.5	0.6	2.8	0.6	-1.7	1.0	0.1	-0.4	-0.4	0.3	0.7	0.4	-1.2	-0.2	-0.6	1.6	-0.3	0.9	-0.2	-0.8	-0.5
Health satisfaction	1.4	1.8	4.4	1.1	1.2	-0.3	1.0	1.2	1.1	1.8	2.1	1.6	0.9	1.5	1.3	-0.4	1.6	2.0	1.6	0.7	1.3
Shortness of breath walking on level ground	1.4	1.7	3.8	1.9	1.5	-1.5	1.2	1.3	1.5	1.6	1.0	1.2	1.1	1.5	0.9	-1.9	1.3	0.3	0.7	0.8	0.8
Qualifications: College or University degree	0.3	0.9	2.6	0.4	0.2	0.9	0.5	1.1	1.0	0.7	1.0	0.9	0.8	0.7	1.2	0.5	1.2	0.9	1.3	1.0	1.6
Eye problems/disorders: None of the above	0.4	0.5	2.3	-0.6	1.5	-0.1	-0.5	0.2	0.0	-0.2	-0.9	-0.3	0.6	0.2	0.5	-1.5	0.2	-1.3	-0.1	0.1	0.2
Mouth/teeth dental problems: Loose teeth	1.9	2.3	5.2	2.3	0.9	-0.1	1.1	1.5	1.5	1.8	2.2	1.2	1.3	1.2	1.4	-1.2	1.6	1.4	1.6	1.4	2.0
Emphysema/chronic bronchitis	0.2	0.2	0.5	0.3	0.7	-0.3	0.6	0.5	0.5	0.6	0.1	0.5	0.0	-0.3	0.7	0.1	0.6	0.1	0.5	0.5	0.3
Medication for pain relief, constipation, heartburn	0.6	1.1	5.8	-0.4	-0.5	2.4	-1.4	-0.4	-0.6	-1.4	-1.2	-0.9	-0.8	-0.2	-0.3	0.3	-0.7	-1.9	-0.9	-0.1	-0.3
Neck or shoulder pain in last month	0.2	0.3	1.6	0.4	0.6	-0.5	0.7	0.5	0.5	0.0	-0.9	0.1	0.5	-0.0	0.5	-0.8	0.4	-0.5	0.4	1.3	0.6
Medication: Blood pressure	0.2	0.3	1.4	-0.8	0.1	0.6	-1.2	-0.3	-0.4	-0.9	0.1	-1.0	0.4	-0.9	-0.1	-0.1	-0.2	-0.5	-0.4	-0.1	-0.0
Angina (self-reported)	1.1	1.4	5.2	1.4	1.1	-1.3	0.8	1.4	1.6	0.8	-0.2	0.6	0.9	0.7	1.2	-2.3	1.2	-0.7	0.6	1.4	1.3
Migraine (self-reported)	1.0	1.3	5.9	-0.0	-2.4	1.1	-0.3	-1.1	-0.9	-0.8	-0.1	-0.7	-1.5	-1.2	-1.4	1.8	-1.1	-0.1	-1.0	-0.8	-1.0
Medication: Ibuprofen	0.9	1.1	2.3	1.4	1.0	-0.7	0.8	0.9	1.0	0.8	1.3	0.6	1.5	-0.1	0.8	-1.4	0.8	0.8	1.1	1.2	1.4
Medication: Allopurinol	0.2	0.3	0.8	0.9	0.3	-0.1	0.6	0.7	0.9	0.5	0.3	0.6	0.1	0.5	0.5	-0.5	0.6	-0.1	0.3	0.2	0.2
Medication: Omeprazole	0.6	0.7	3.7	-0.6	1.0	-1.9	1.2	0.3	0.2	1.1	0.9	0.6	0.3	0.2	0.5	-0.5	0.7	1.3	0.9	-0.0	0.1
Medication: Seretide 50 evohaler	0.9	1.0	3.2	-0.2	-1.5	0.9	-1.3	-0.4	-0.2	-0.7	0.3	-1.2	-1.1	-0.4	-0.8	0.6	-0.5	-1.8	-1.7	-1.2	-0.8
Mean time to correctly identify matches	1.1	2.0	5.0	0.5	2.2	-2.0	1.7	0.9	0.8	1.8	1.1	1.4	0.8	1.5	1.1	-1.4	1.2	2.2	1.7	1.0	0.8
Heart disease (mother)	0.2	0.2	0.9	0.6	-0.2	-0.6	0.1	0.8	0.9	0.1	-0.4	0.6	0.3	0.0	0.7	-0.1	0.7	-0.1	0.1	0.2	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.8	5.4	-1.6	-1.2	1.0	-2.1	-1.6	-1.6	-2.0	-1.4	-1.8	-1.7	-1.2	-1.5	0.3	-1.6	-1.8	-2.1	-2.3	-2.2
Whole body fat mass	0.4	1.7	5.2	1.1	0.9	-2.0	1.7	0.6	0.6	2.0	2.0	1.4	0.2	1.0	0.7	-0.2	1.1	2.3	1.3	0.5	0.5
Leg fat mass (right)	0.5	1.9	7.2	1.1	0.9	-2.7	1.8	0.6	0.6	2.1	2.0	1.6	0.2	1.0	0.6	-0.2	1.1	2.5	1.2	0.3	0.4
Arm predicted mass (right)	0.2	0.8	3.1	-0.4	-1.4	-0.9	-0.4	-1.0	-1.0	-0.0	1.3	-0.4	-0.8	-0.9	-0.9	1.3	-0.6	1.8	-0.1	-0.5	-0.3
Pulse rate, automated reading	0.4	1.2	3.0	-1.6	0.7	-0.5	-1.4	-0.8	-1.1	-1.2	-1.7	-1.3	-0.1	-1.7	-0.3	-0.9	-0.6	-1.5	-0.9	-0.7	-0.9
Alcohol intake frequency.	0.1	0.2	1.0	0.4	-0.7	0.2	0.5	0.1	0.1	0.4	0.0	0.2	-1.0	0.8	0.1	0.7	0.4	0.3	0.1	-0.3	-0.5
Comparative height size at age 10	1.0	5.6	20.9	-2.8	-3.5	0.7	-1.2	-2.2	-2.4	-2.7	-2.2	-1.9	-2.9	-2.7	-1.7	4.6	-2.2	-0.4	-1.4	-1.3	-2.1
Number of full sisters	1.5	1.8	7.3	0.2	1.8	-2.7	1.9	1.4	1.4	1.2	-0.9	1.7	1.1	0.7	1.3	-0.9	1.2	0.9	1.3	0.8	0.4
Suffer from ‘nerves’	0.3	0.4	1.6	-0.2	-0.6	-1.2	0.4	-0.8	-0.8	-0.5	-0.6	0.1	-0.6	0.4	-0.9	0.8	-1.0	0.4	-0.3	0.0	-0.8
Overall health rating	0.5	1.1	8.0	0.1	1.5	-2.8	1.2	0.4	0.3	0.9	0.3	1.0	0.6	0.5	0.7	-0.9	0.7	1.4	1.1	0.8	0.3
Chest pain or discomfort	5.1	7.3	13.0	3.2	1.5	-2.9	3.2	2.8	3.0	3.6	2.9	3.0	2.5	2.6	2.2	-1.5	2.9	2.8	2.8	1.9	2.4
Had major operations	0.3	0.3	1.3	0.5	-0.1	-0.0	-0.3	0.4	0.5	-0.6	-0.5	-0.6	0.9	-0.5	0.3	-0.3	0.1	-1.2	-0.1	1.2	0.6
Age at last live birth	0.3	0.4	1.0	0.7	0.7	0.4	0.0	0.8	0.8	0.3	0.0	0.3	0.8	1.0	0.7	-0.5	0.7	-0.2	0.3	0.5	0.7
Family relationship satisfaction	0.9	1.1	3.9	1.3	-1.2	0.2	1.2	0.5	0.8	1.4	1.4	1.5	-0.4	0.8	0.1	2.0	0.5	1.7	0.5	-0.0	0.1
Leg pain on walking	1.8	2.2	4.8	0.9	1.4	-1.9	1.8	1.4	1.5	1.6	1.3	1.4	1.4	2.2	1.4	-1.1	1.4	1.2	1.6	1.5	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.5	3.2	-0.7	0.7	-0.6	-0.4	-0.2	-0.2	-0.8	-1.8	-0.5	-0.1	-0.2	-0.1	-0.7	-0.4	-1.5	-0.6	-0.5	-0.8
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.6	0.5	-0.3	0.7	0.3	0.1	0.2	0.5	1.3	-0.0	-0.6	-0.5	-0.2	0.2	0.1	0.3	-0.1	-0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.3	-0.2	-0.9	1.0	-0.2	-0.5	-0.5	-0.4	-1.8	0.3	-0.7	-0.2	-0.4	0.9	-0.5	0.4	-0.2	-0.4	-0.6
Medication: Aspirin	0.3	0.3	2.4	0.0	0.6	-1.5	0.8	0.3	0.4	0.3	-0.8	0.7	-0.4	0.1	0.3	-0.4	0.3	0.6	0.3	0.1	-0.5
Supplements: Vitamin C	2.2	2.6	6.7	0.8	2.1	-0.5	1.2	1.9	1.8	1.4	0.3	1.0	2.0	2.6	2.1	-2.2	2.0	0.4	1.6	1.4	1.6
Knee pain experienced in last month	0.3	0.4	1.0	-0.7	-0.1	-0.2	-0.1	-0.7	-0.7	-0.5	-0.6	-0.6	-0.8	-0.4	-0.6	0.1	-0.7	-0.9	-0.7	-0.6	-1.0
Hypertension (Self-reported)	0.2	0.6	3.4	-1.8	0.3	-0.1	-1.1	-0.8	-1.0	-1.1	-0.4	-0.9	-0.2	-0.4	-0.4	0.5	-0.6	0.1	-0.5	-0.7	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	1.9	7.5	-0.2	1.4	-2.7	2.1	0.9	0.7	1.5	0.7	1.6	0.8	1.6	1.2	-0.0	1.2	2.1	1.9	0.7	0.5
Illnesses of father: Heart disease	0.1	0.2	0.9	-0.8	0.4	0.2	-0.2	0.1	0.1	0.3	0.5	-0.3	-1.0	0.7	0.2	0.2	0.3	-0.1	-0.1	-0.5	-0.3
Illnesses of siblings: Diabetes	1.1	1.4	3.4	-1.4	-1.4	-0.9	-0.4	-1.1	-1.1	-1.1	-0.4	-0.6	-1.3	-1.1	-1.2	1.8	-1.3	-0.2	-1.0	-1.6	-1.8
Smoking status: Previous	7.4	11.1	20.3	-4.4	-1.9	1.6	-3.5	-3.2	-3.4	-4.5	-3.3	-4.1	-2.6	-4.5	-2.8	1.6	-3.5	-4.0	-3.5	-2.2	-3.0
Forced expiratory volume in 1-second (FEV1), predicted	0.5	0.9	2.9	-0.8	-1.4	0.0	-0.8	-0.7	-0.7	-1.2	-0.7	-1.0	-1.4	-1.2	-0.7	1.7	-0.9	-0.8	-0.8	-0.3	-0.6
Whole body fat-free mass	0.2	1.1	5.4	-0.2	-1.7	-0.9	-0.0	-1.0	-1.0	0.2	1.6	-0.2	-0.8	-1.0	-0.9	1.9	-0.6	2.3	0.1	-0.3	-0.1
Leg fat-free mass (right)	0.1	0.7	3.6	-0.0	-1.3	-0.7	0.0	-0.7	-0.7	0.4	1.5	-0.2	-0.6	-0.9	-0.6	1.3	-0.3	1.9	0.2	-0.1	0.2
Arm fat percentage (left)	1.5	5.9	13.2	2.5	2.2	-2.5	3.0	2.1	2.1	3.6	2.7	2.9	1.3	2.6	2.0	-1.2	2.6	3.2	2.6	1.2	1.5
Average weekly red wine intake	0.7	1.1	5.9	-0.5	-1.7	2.1	-0.8	-0.6	-0.7	-0.7	0.8	-0.8	-1.1	-1.1	-0.6	2.4	-0.5	0.1	-0.3	-0.1	0.1
Handedness (chirality/laterality): Left-handed	0.8	0.9	4.6	0.2	-1.5	-0.4	1.1	-0.4	-0.1	1.0	0.7	0.9	-0.9	0.1	-0.7	2.1	-0.3	1.8	0.0	-1.0	-0.9
Mood swings	0.3	0.5	2.8	-0.9	-0.4	0.2	0.0	-0.6	-0.7	-0.0	0.9	0.1	-0.5	-0.4	-0.4	1.7	-0.3	1.5	0.2	-0.1	-0.4
Loneliness, isolation	1.3	1.8	5.6	0.7	0.9	-2.1	2.1	0.6	0.5	1.7	0.7	1.8	0.6	2.0	0.7	-0.3	0.9	2.4	1.7	0.7	0.5
Long-standing illness, disability or infirmity	0.4	0.6	4.8	0.4	0.3	-2.2	1.5	0.4	0.4	0.4	-0.1	0.5	0.4	-0.5	0.3	0.1	0.2	0.7	0.8	1.0	0.2
Ever had bowel cancer screening	1.4	1.6	6.0	1.4	0.5	0.0	1.6	1.6	1.8	1.4	0.2	1.6	0.3	2.4	1.2	-0.3	1.3	0.6	1.2	1.0	1.0
Diabetes diagnosed by doctor	0.2	0.3	1.7	-0.1	0.9	-1.3	0.3	0.4	0.4	-0.3	-0.8	0.3	-0.3	0.5	0.7	-0.1	0.5	-0.5	0.3	0.6	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	4.8	0.9	1.1	-1.2	1.5	1.2	1.1	1.7	0.5	1.9	0.7	2.2	1.2	0.0	1.3	1.5	1.5	0.6	0.8
Friendships satisfaction	1.2	1.5	8.0	0.5	-1.1	-0.5	1.7	0.0	0.2	1.1	1.0	2.1	-0.6	0.5	-0.2	2.5	0.1	2.8	0.9	-0.1	-0.4
Qualifications: nursing, teaching	0.7	1.1	3.5	1.0	-0.9	-0.7	1.8	0.4	0.6	1.2	1.3	1.6	-0.4	0.8	0.1	1.9	0.4	1.6	0.8	0.2	0.3
Commuting to job workplace: Walk	0.4	0.5	1.8	-1.0	0.2	-1.3	-0.8	-0.5	-0.7	-1.1	-0.9	-0.7	0.3	-0.1	-0.1	-0.5	-0.5	-0.7	-0.1	0.7	0.2
Eye problems/disorders: Cataract	0.6	0.7	2.3	0.7	-0.8	-0.7	0.8	0.7	0.9	1.0	1.4	0.9	0.2	0.8	0.4	1.2	0.8	1.5	0.6	-0.2	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.6	-0.3	0.2	1.1	-0.4	-0.0	-0.2	-0.4	-0.2	-0.2	1.3	-0.3	0.3	-0.2	-0.1	-0.2	0.3	1.0	0.8
Medication for cholesterol	0.7	1.0	4.1	0.9	0.8	0.8	-0.1	0.7	0.7	-0.2	0.4	-0.3	1.9	-0.1	0.7	-1.5	0.4	-0.8	0.6	1.9	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.3	0.6	0.6	-0.6	0.8	0.3	0.3	0.7	0.4	0.5	0.7	0.5	0.4	-0.1	0.3	1.1	0.8	0.4	0.6
Back pain experienced in last month	0.4	0.5	3.1	0.1	1.5	-0.3	-0.0	0.4	0.2	0.3	0.5	-0.3	1.2	0.4	0.5	-1.8	0.5	-0.6	0.3	0.5	0.7
Mineral and other dietary supplements	0.4	0.5	4.1	-0.5	-1.3	0.8	-0.2	-0.5	-0.5	-0.2	0.2	-0.4	-0.4	-0.5	-0.5	2.0	-0.5	0.7	-0.1	-0.4	-0.2
Breast cancer (self-reported)	1.4	1.7	7.8	-0.7	-0.8	2.8	-2.3	-0.5	-0.5	-1.5	0.3	-2.1	-0.4	-1.1	-0.4	0.2	-0.6	-2.2	-1.3	-0.5	0.1
Asthma (self-reported)	0.1	0.3	1.3	-0.7	-0.7	1.1	-0.6	0.1	0.1	-0.6	0.4	-0.8	-0.1	0.1	0.2	0.7	0.2	-0.7	-0.2	0.0	0.3
Osteoporosis (self-reported)	1.1	1.3	3.5	-1.9	-0.2	-0.9	-1.1	-0.9	-1.0	-1.7	-1.8	-1.0	-0.2	-1.5	-0.7	0.5	-1.2	-1.6	-1.0	-0.6	-1.0
Osteoarthritis (self-reported)	0.2	0.3	1.9	-0.1	0.4	0.1	-0.2	-0.3	-0.4	-0.1	1.0	-0.4	1.1	-1.4	-0.2	-0.7	-0.2	0.1	0.1	0.5	0.5
Medication: Aspirin	0.3	0.4	2.5	0.3	0.7	-1.6	0.9	0.6	0.6	0.4	-0.4	0.8	0.1	0.1	0.6	-0.3	0.5	0.9	0.7	0.5	0.0
Medication: Gliclazide	0.1	0.2	0.5	-0.1	0.6	-0.5	0.5	0.4	0.3	0.0	-0.1	0.3	-0.3	0.2	0.5	0.7	0.4	-0.0	0.5	0.4	0.1
Illnesses of father: None of the above (group 1)	1.4	1.7	5.5	2.3	0.6	-0.2	0.9	1.0	1.1	1.3	1.5	1.3	2.3	0.8	0.7	-1.6	0.8	0.9	1.1	1.4	1.7
Smoking status: Current	0.3	0.4	3.2	0.5	0.7	-1.8	0.2	0.1	0.1	0.2	-0.8	-0.1	0.3	0.7	0.1	-1.2	-0.0	-0.8	-0.1	-0.0	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	3.0	-1.4	-1.1	1.7	-1.5	-1.3	-1.2	-1.2	-1.1	-1.4	-1.4	-0.6	-1.4	0.9	-1.2	-0.9	-1.7	-1.6	-1.7
Whole body water mass	0.2	1.3	5.6	-0.3	-1.9	-0.8	-0.1	-1.1	-1.1	0.1	1.6	-0.2	-1.0	-1.0	-1.0	2.1	-0.7	2.4	0.1	-0.4	-0.2
Leg predicted mass (right)	0.1	0.7	3.3	-0.1	-1.2	-0.7	-0.0	-0.7	-0.7	0.3	1.5	-0.3	-0.5	-0.9	-0.6	1.2	-0.3	1.8	0.2	-0.1	0.2
Arm fat mass (left)	0.8	3.3	10.7	1.8	1.0	-2.2	2.4	1.1	1.1	2.9	2.6	2.2	0.5	1.6	1.1	-0.2	1.7	3.3	1.9	0.6	0.9
Number of self-reported non-cancer illnesses	0.1	0.2	2.0	-0.5	0.0	-1.4	0.5	-0.2	-0.3	-0.2	0.0	0.1	-0.3	-0.2	-0.1	0.7	-0.1	0.9	0.3	-0.1	-0.5
Average weekly champagne plus white wine intake	0.3	0.4	2.0	-0.2	1.4	0.1	0.2	0.6	0.4	0.1	-1.0	0.6	0.3	0.3	0.8	-1.0	0.5	0.1	0.7	0.7	0.5
Miserableness	0.3	0.5	3.0	-0.4	-0.5	-0.0	0.4	-0.5	-0.5	0.7	1.1	0.5	-0.4	0.6	-0.5	1.2	-0.2	1.7	0.1	-0.8	-0.7
Guilty feelings	0.1	0.1	0.5	0.1	0.3	-0.0	-0.6	-0.0	-0.1	-0.6	-0.1	-0.3	0.1	-0.2	0.0	-0.2	-0.2	-0.4	-0.1	0.7	0.3
Wears glasses or contact lenses	1.4	1.6	3.1	-0.9	-1.8	0.3	-1.5	-1.6	-1.5	-1.5	0.5	-1.5	-0.8	-0.8	-1.5	1.6	-1.6	-0.4	-1.4	-1.2	-1.3
Ever taken oral contraceptive pill	1.8	2.0	3.4	-1.6	-1.3	0.7	-1.6	-1.6	-1.6	-1.4	-0.4	-1.5	-1.8	-1.2	-1.5	1.3	-1.6	-0.8	-1.6	-1.8	-1.5
Hearing aid user	0.1	0.1	0.7	-0.1	-0.2	0.1	0.2	-0.1	-0.1	-0.4	-0.5	0.0	-0.2	-0.8	-0.2	0.2	-0.4	0.1	0.1	0.2	-0.1
Mother’s age at death	0.8	1.0	5.4	0.2	1.1	-0.8	0.1	0.6	0.5	-0.6	-1.2	-0.4	1.4	0.5	0.8	-2.3	0.2	-1.4	0.4	1.5	0.9
Financial situation satisfaction	1.4	1.7	7.5	1.2	0.5	-0.8	1.2	0.8	0.8	1.9	2.4	1.6	0.7	0.7	0.6	0.5	1.1	2.7	1.4	0.6	1.2
Tinnitus: Yes, now most or all of the time	0.9	1.1	7.7	0.0	0.0	1.5	-1.2	0.2	0.3	-1.1	-1.1	-1.5	0.2	-0.9	0.0	-0.9	-0.1	-2.8	-1.1	-0.0	0.0
Commuting to job workplace: Public transport	0.9	1.1	3.6	-0.2	1.6	-1.4	-0.2	1.0	0.8	0.6	0.1	0.2	1.9	0.9	1.2	-1.6	1.2	-0.1	0.9	0.5	1.3
Eye problems/disorders: Glaucoma	0.7	0.9	5.0	-0.0	-1.4	2.2	-1.3	-0.8	-0.8	-0.4	1.4	-0.9	-0.4	-0.8	-0.9	0.5	-0.6	0.3	-0.7	-0.5	-0.0
Medication: Blood pressure	0.2	0.4	1.8	-0.6	0.1	-1.3	0.6	-0.1	-0.1	0.2	-0.8	0.6	-0.7	0.2	-0.1	0.7	0.0	1.0	0.1	-0.6	-1.0
Pain type(s) experienced in last month: Hip pain	0.3	0.4	3.5	0.3	0.1	-1.9	0.5	0.4	0.4	-0.1	-0.1	0.1	0.6	0.1	0.2	-0.3	0.1	-0.4	0.2	1.0	0.7
Supplements: Fish oil (including cod liver oil)	0.4	0.6	4.8	0.6	1.4	-0.3	0.5	0.5	0.6	0.6	0.1	0.6	0.4	0.6	0.5	-2.2	0.5	-0.3	0.3	0.4	0.3
High cholesterol (Self-reported)	2.1	3.7	6.6	-2.3	-1.1	0.4	-2.0	-2.3	-2.4	-1.9	-1.4	-2.0	-2.3	-1.3	-2.1	0.5	-2.2	-1.1	-2.2	-2.4	-2.6
Medication: Bendroflumethiazide	0.4	0.7	3.5	-0.2	0.3	0.8	-1.1	0.4	0.3	-1.0	-1.7	-0.8	-0.0	-0.9	0.5	-0.3	0.2	-1.9	-0.6	0.1	-0.0
Medication: Paracetamol	0.5	0.8	3.1	-0.7	-0.8	-1.8	-0.5	-0.5	-0.4	-0.7	-0.7	-0.7	-0.2	-1.5	-0.7	0.7	-0.7	-0.8	-1.0	-0.9	-1.0
Medication: Lisinopril	2.9	3.7	6.2	-2.5	-1.4	1.8	-2.4	-2.1	-2.3	-2.1	-1.0	-2.0	-2.3	-1.5	-1.6	2.2	-1.8	-0.6	-1.8	-2.2	-2.2
Medication: Atorvastatin	0.6	0.8	2.0	-1.0	-0.4	0.5	-1.3	-0.6	-0.7	-1.1	-0.9	-1.1	-1.3	-0.7	-0.5	0.3	-0.6	-1.4	-1.0	-0.8	-0.7
Illnesses of father: High blood pressure	0.7	0.9	2.0	-1.4	-1.0	0.3	-1.2	-0.8	-0.9	-1.4	-0.7	-1.0	-1.1	0.2	-0.6	1.4	-0.7	-0.5	-0.9	-0.9	-1.0
Alcohol drinker status: Never	0.7	0.9	5.8	0.1	-1.4	0.2	0.7	-0.2	-0.1	0.1	-0.2	0.7	-1.9	0.6	-0.4	2.4	-0.2	1.0	-0.1	-0.7	-1.0
Ever smoked	1.6	2.7	9.0	-2.0	-0.2	-0.2	-1.5	-1.4	-1.7	-2.6	-2.0	-2.4	-0.5	-2.2	-1.1	0.1	-1.8	-3.0	-1.4	-0.3	-0.9
Basal metabolic rate	0.2	1.2	7.3	0.1	-1.5	-1.3	0.4	-0.7	-0.7	0.7	1.9	0.3	-0.8	-0.7	-0.7	1.9	-0.3	2.7	0.4	-0.2	0.0
Leg fat percentage (left)	0.7	2.4	7.1	1.3	1.5	-2.7	2.1	1.0	1.1	2.4	1.8	1.9	0.4	1.8	0.9	-0.7	1.5	2.2	1.3	0.4	0.3
Arm fat-free mass (left)	0.2	1.1	7.4	0.0	-1.3	-1.4	0.3	-0.7	-0.7	0.6	1.9	0.2	-0.7	-0.5	-0.7	1.6	-0.2	2.7	0.4	-0.4	-0.1
Number of operations (self-reported)	0.3	0.4	2.8	0.7	-0.5	0.6	-0.6	0.2	0.3	-0.3	1.7	-0.7	0.2	-0.6	0.1	0.1	0.1	-0.9	-0.2	0.6	0.8
Average weekly beer plus cider intake	0.8	1.2	3.5	0.0	-0.4	1.4	-1.5	-0.8	-0.6	-0.9	-0.8	-1.4	-0.1	-0.5	-1.1	-1.4	-1.0	-1.9	-1.8	-1.2	-1.0
Irritability	0.9	1.5	6.5	-1.0	-1.7	-0.6	0.4	-1.2	-1.3	-0.6	-1.3	0.2	-1.8	-0.5	-1.0	2.5	-1.1	1.4	-0.2	-0.6	-1.5
Risk taking	2.0	3.0	6.7	2.6	0.8	0.1	2.2	1.8	1.8	2.1	1.0	2.2	1.1	2.2	1.6	-1.0	1.7	1.5	2.0	1.7	1.7
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.2	0.1	-0.7	0.1	0.4	-0.4	-0.2	0.4	-0.0	-0.0	-0.8	-0.9	-0.6	0.5	-0.4	0.2	-0.5	-1.0	-1.1
Fractured/broken bones in last 5 years	2.5	3.2	5.9	1.4	2.1	-2.3	1.8	1.3	1.3	1.6	1.7	1.2	1.9	1.8	1.3	-2.4	1.2	1.3	2.0	2.3	2.4
Age started oral contraceptive pill	0.4	0.6	1.2	1.1	-0.1	1.1	0.5	0.9	1.0	0.6	0.6	0.5	0.7	0.6	0.7	-0.6	0.7	0.3	0.7	0.7	1.1
Diastolic blood pressure, automated reading	0.6	1.8	7.9	-1.5	-0.6	0.2	-1.0	-1.3	-1.3	0.6	1.8	-0.5	-1.5	-0.5	-1.1	1.9	-0.4	1.6	-0.8	-2.8	-1.6
Ever depressed for a whole week	2.0	2.5	5.5	1.8	0.9	-2.3	2.1	1.6	1.8	1.9	1.2	2.3	0.6	2.0	1.2	-0.2	1.5	1.6	1.5	1.1	1.0
Unable to work because of sickness or disability	0.4	0.5	2.8	0.6	-0.6	-1.7	1.1	-0.0	0.1	0.6	-0.5	0.4	-0.7	-1.2	-0.3	0.5	-0.0	0.7	0.1	-0.1	-0.4
Commuting to job workplace: Cycle	2.1	2.5	3.6	1.6	1.1	-1.7	1.5	1.8	1.8	1.2	0.8	1.9	1.9	1.4	1.8	-0.4	1.7	1.4	1.9	1.8	1.8
Myopia	0.5	0.7	1.9	0.3	-1.4	1.0	-1.1	-0.6	-0.5	-0.7	0.6	-1.1	-0.4	-1.2	-0.8	0.3	-0.8	-1.2	-1.2	-0.4	-0.3
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.7	1.9	-0.5	0.7	1.2	0.7	0.9	1.5	1.0	1.2	-0.1	0.7	0.3	0.1	0.7	0.5	0.5	0.3	0.6
Cholesterol lowering medication	0.3	0.5	1.5	-0.7	-0.0	-0.9	-0.7	-0.3	-0.3	-0.4	-0.6	-0.5	-1.2	-0.1	-0.3	-0.4	-0.2	-0.8	-0.8	-1.1	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	3.4	-1.0	0.7	-1.9	0.6	-0.2	-0.4	0.2	0.2	-0.1	-0.1	-0.0	0.1	-0.6	0.1	0.3	0.4	-0.0	-0.3
Pain experienced in last month	0.1	0.1	0.5	0.1	0.2	0.7	-0.1	0.3	0.3	0.5	0.7	0.4	0.3	0.3	0.3	-0.0	0.4	0.5	0.3	-0.1	0.4
Supplements: Calcium	0.8	0.9	2.4	1.0	0.5	-1.1	1.1	1.3	1.3	0.1	-0.8	0.7	0.3	0.1	1.3	-0.1	1.0	-0.5	0.9	1.6	0.9
Basal cell carcinoma (self-reported)	0.3	0.4	2.2	1.1	0.2	0.5	-0.1	0.6	0.7	0.6	1.5	0.1	0.1	0.9	0.4	-0.7	0.6	-0.1	0.1	0.3	0.8
Heart attack/myocardial infarction (self-reported)	0.3	0.4	3.3	0.3	0.5	-1.8	0.6	0.1	0.1	0.1	-0.7	0.5	0.4	-0.7	0.1	-0.5	0.0	0.7	0.4	0.6	0.0
Deep venous thrombosis (DVT) (self-reported)	2.9	3.8	11.8	1.1	2.5	-3.4	2.3	1.7	1.8	1.7	-0.3	2.1	2.1	2.2	1.6	-2.7	1.6	1.2	1.8	1.4	1.1
Heart disease (siblings)	0.1	0.2	1.3	-0.0	-0.1	0.2	0.6	-0.0	-0.0	0.6	0.4	0.4	-0.2	0.2	-0.0	-0.0	0.1	1.1	0.4	-0.2	-0.0
Alcohol drinker status: Previous	0.5	0.6	1.5	1.1	0.2	0.2	1.0	1.1	1.2	1.1	0.4	0.8	0.5	0.1	0.9	-0.1	1.2	0.3	0.7	0.5	0.5
Pack years of smoking	0.5	0.7	3.5	0.1	1.3	-0.9	-0.5	0.2	0.1	-0.7	-0.1	-0.9	1.1	0.1	0.4	-1.9	-0.1	-1.3	0.1	1.0	0.8
Impedance of whole body	0.1	0.7	3.3	-0.3	1.1	0.1	0.7	0.8	0.6	-0.6	-1.8	0.2	0.3	0.3	1.1	-0.2	0.5	-1.6	0.6	1.1	0.3
Leg fat mass (left)	0.4	1.7	6.8	0.9	0.9	-2.6	1.6	0.6	0.6	2.0	1.9	1.4	0.2	1.1	0.6	-0.2	1.1	2.3	1.1	0.3	0.3
Arm predicted mass (left)	0.2	1.1	6.4	0.1	-1.4	-1.4	0.1	-0.9	-0.9	0.5	2.0	-0.0	-0.6	-0.6	-0.9	1.6	-0.4	2.5	0.2	-0.4	-0.1