Hub : Genes

LINC00649

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1060	0.0480	7.8e-03	0.018	NA	0.001	NA	0.003	1.6e-02	NA	2.8e-01	NA	1.9e-01
2	GTEx	Esophagus Mucosa	0.1730	0.0460	8.5e-07	0.126	NA	0.160	NA	0.139	9.7e-09	NA	7.2e-11	NA	1.6e-09
3	GTEx	Lung	0.0834	0.0336	3.4e-03	0.042	NA	0.045	NA	0.055	3.6e-04	NA	2.2e-04	NA	4.7e-05
4	GTEx	Prostate	0.6530	0.1010	3.1e-04	-0.010	NA	0.042	NA	0.021	6.6e-01	NA	3.3e-02	NA	9.7e-02
5	GTEx	Skin Not Sun Exposed Suprapubic	0.1350	0.0530	6.3e-03	0.007	NA	0.034	NA	0.024	1.3e-01	NA	5.5e-03	NA	1.6e-02
6	GTEx	Skin Sun Exposed Lower leg	0.1330	0.0370	1.9e-06	0.138	NA	0.091	NA	0.078	1.7e-11	NA	5.3e-08	NA	4.8e-07
7	GTEx	Thyroid	0.1130	0.0420	4.3e-03	0.088	NA	0.075	NA	0.081	3.1e-07	NA	2.2e-06	NA	9.3e-07
8	GTEx	Whole Blood	0.0810	0.0290	1.0e-04	0.038	NA	0.049	NA	0.053	1.7e-04	NA	2.3e-05	NA	1.1e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	1.0	3.8	0.4	0.1	1.8	0.5	-0.2	-0.2	2.0	0.5
Bipolar Disorder or Schizophrenia	0.3	0.8	2.3	-1.5	-0.5	0.8	0.3	-1.4	-0.1	0.8	0.6
Depressed Affect (Nagel 2018)	0.3	0.7	1.6	0.0	-1.1	-0.1	-1.1	0.1	-1.3	0.2	-1.2
Depression (Nagel 2018)	0.2	0.3	0.6	-0.6	-0.3	-0.4	-0.4	-0.8	-0.5	-0.1	-0.8
Intelligence (Savage-Jansen 2018)	0.6	1.7	4.3	-1.2	1.4	0.6	0.7	1.5	1.7	0.1	2.1
Neuroticism (Nagel 2018)	0.9	2.1	5.6	0.9	-1.8	-0.8	-0.9	-1.1	-2.0	-0.3	-2.4
Schizophrenia (2018)	0.5	1.1	5.2	-2.3	-0.7	-0.5	-0.0	-1.6	0.0	-0.5	0.4
Schizophrenia vs Biploar Disorder	2.3	3.0	9.6	-3.1	-1.3	-1.9	-0.8	-2.0	-0.1	-2.0	-0.0
Worry (Nagel 2018)	0.8	1.6	3.6	1.3	-1.3	-0.5	-1.1	-1.4	-1.6	-0.1	-1.9
Alzheimer’s Disease (in mother)	0.3	0.4	1.1	0.5	-0.1	-0.6	-0.0	-1.0	0.0	-0.9	-0.6
Alzheimer’s Disease (in father)	0.2	0.2	1.3	1.1	-0.5	-0.1	-0.1	-0.4	-0.0	-0.0	-0.2
Alzheimer’s Disease (including proxy)	0.2	0.3	1.1	0.6	-0.1	-0.7	0.3	-1.0	0.4	-0.6	-0.4
Crohns Disease (2017)	0.4	0.9	2.3	-0.4	0.0	-1.3	-0.7	-1.5	-0.2	-1.5	0.2
Irritable Bowel Disease (IBD)	0.3	0.8	2.0	-0.8	-0.4	-0.7	-1.4	-1.4	-0.6	-0.9	0.0
Ulcerative Colitis (UC)	0.4	0.7	2.9	-0.5	-0.7	-0.3	-1.7	-1.0	-0.9	-0.4	-0.3
Major Depression (MDD)	1.8	2.2	4.7	-2.1	1.1	1.6	-0.2	0.5	1.5	1.6	2.2
Reaction Time	0.8	1.5	2.7	1.6	1.2	1.6	0.8	0.8	1.0	1.6	0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.4	2.6	-0.5	1.4	1.2	1.0	1.5	1.6	0.9	1.0
Breast Cancer	0.3	0.8	1.9	1.1	-0.9	-0.5	-0.0	-0.7	-1.2	-0.4	-1.4
Ovarian Cancer	0.3	0.4	2.1	-0.4	-0.5	-0.6	-1.5	0.0	-0.1	-0.8	-0.3
Prostate Cancer	1.5	2.1	5.0	-1.9	-0.5	-1.3	-1.9	-2.2	-0.1	-1.4	-0.5
Age at First Birth	0.9	1.3	2.9	1.1	-0.8	-1.1	1.7	-1.5	-0.4	-1.2	-0.8
Bipolar Disorder (2011)	2.2	2.2	5.7	-0.0	1.4	2.1	-0.2	1.0	1.4	2.4	1.5
Body Mass Index (BMI) (2010)	1.4	1.9	3.6	-0.1	-1.6	-1.9	-0.6	-1.3	-1.6	-1.8	-0.9
Coronary Artery Disease (CAD)	0.8	1.0	2.9	-0.0	1.7	-0.0	-1.6	0.6	1.0	-0.0	1.1
Crohns Disease (2012)	0.3	0.4	1.4	0.7	0.8	0.1	0.1	-0.7	0.7	-0.1	1.2
Mean Putamen Volume	0.6	0.7	2.6	0.1	0.1	-1.5	0.1	-0.0	0.7	-1.6	0.4
Fasting Glucose	2.0	2.4	5.3	-0.5	-1.3	-2.0	-1.5	-2.3	-1.1	-1.9	-0.5
HbA1C	0.9	1.0	3.8	-0.4	-0.5	-0.9	-1.2	-1.9	-1.0	-1.0	-0.1
HDL Cholesterol	1.0	1.7	3.0	0.1	1.4	1.7	-0.3	1.5	1.3	1.7	1.3
LDL Cholesterol	0.7	1.2	2.5	-0.6	-1.3	-1.3	-0.0	-1.6	-1.2	-1.3	0.0
Lupus	1.5	2.2	11.8	-3.4	0.3	-0.7	-0.2	-0.6	1.4	-0.8	1.6
Neuroticism (2016)	0.3	0.4	1.5	-1.2	-0.4	0.3	-0.8	0.5	-0.4	0.5	-0.6
Primary Biliary Cirrhosis	0.2	0.3	0.6	0.8	0.7	0.2	-0.1	0.8	0.6	0.1	-0.1
Rheumatoid Arthritis	0.1	0.1	0.3	-0.4	0.3	-0.2	-0.0	-0.1	0.5	-0.1	0.4
Schizophrenia (2014)	0.5	1.0	5.3	-2.3	-0.3	0.2	-0.0	-1.2	0.6	0.4	1.0
Triglycerides	0.5	0.8	3.3	-1.8	0.2	-0.7	-1.4	-0.2	0.1	-1.0	0.1
Type 2 Diabetes (T2D) (2012)	1.1	1.2	2.8	0.1	-1.3	-1.0	1.7	0.2	-1.5	-1.3	-0.6
Ulcerative Colitis	0.1	0.1	0.4	-0.6	0.1	0.4	-0.5	-0.1	0.2	0.3	0.5
Blood Eosinophil Count	0.1	1.1	5.7	-0.1	1.1	-0.3	-1.0	-0.1	0.7	-0.6	2.4
Blood Platelet Count	1.2	13.9	37.3	-6.1	4.0	-0.6	0.2	2.9	4.8	-1.5	4.8
Blood Red Count	3.0	29.4	72.5	0.8	-7.3	-4.3	-3.5	-5.9	-8.5	-3.5	-5.7
Blood White Count	0.1	0.6	2.3	-0.7	0.8	0.2	-1.5	-0.1	0.9	0.3	0.5
Heel T-Score	0.5	3.8	23.8	0.2	-0.6	0.9	4.9	-1.1	-1.4	1.3	-0.6
BMI	0.2	1.3	2.3	-0.2	-1.5	-0.5	-1.5	-1.1	-1.5	-0.3	-1.3
Height	0.2	3.9	10.7	0.9	-2.3	-1.5	-1.3	-3.3	-1.2	-1.3	-2.6
Waist Hip Ratio (WHR)	1.6	7.3	20.3	-4.3	-0.7	-2.3	-4.5	-2.2	-0.1	-2.5	1.8
Systolic Blood Pressure	0.9	4.7	12.1	0.9	2.9	1.8	1.5	2.4	3.5	1.7	1.5
Smoking Status	0.6	1.4	7.2	-1.2	0.1	-0.4	-2.7	-0.8	0.7	-0.4	1.2
Allergy or Eczema	0.0	0.1	0.3	0.3	-0.6	0.1	0.5	-0.4	-0.3	0.3	0.2
Cardiovascular Disease	0.2	0.7	1.4	1.0	0.7	1.2	0.6	0.8	0.9	1.0	0.1
Hypothyroidism (self reported)	0.5	1.2	3.0	-1.7	-0.0	-1.1	-1.6	-1.0	0.1	-1.0	0.8
Respiratory disease	0.5	1.1	2.7	-1.3	-0.9	-1.0	0.4	-1.6	-1.0	-0.7	-0.9
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.5	-0.2	-1.3	-1.3	-0.7	-1.1	-1.3	-1.6	-1.2
Lung FEV1/FVC ratio	1.5	7.6	28.6	-1.4	-3.3	-2.2	0.9	-5.3	-2.5	-2.4	1.4
Lung FVC	0.3	1.6	8.6	1.4	-0.3	-0.4	-1.0	0.6	-0.8	-0.2	-2.9
Neuroticism	0.4	0.9	2.7	-0.1	-1.1	-0.4	-1.6	-0.9	-1.3	-0.2	-1.0
Chronotype (morning person)	1.1	2.6	6.9	0.9	-2.6	-1.6	0.3	-1.6	-2.3	-1.3	-0.9
Hair Pigment	0.1	1.6	3.9	0.7	0.8	2.0	-0.4	1.9	0.8	1.9	-0.0
Tanning	0.0	0.6	2.2	-0.8	0.5	-0.8	-1.5	-0.4	0.3	-0.8	0.0
Hand grip strength (left)	1.9	5.0	9.2	-0.7	-2.6	-3.0	0.1	-2.2	-2.2	-3.0	-2.2
Number of treatments/medications taken	0.1	0.1	0.3	0.1	0.2	0.5	-0.5	0.1	0.2	0.5	0.2
Average weekly spirits intake	1.3	1.6	4.1	-2.0	-1.5	-1.5	-1.2	-0.7	-1.0	-1.1	0.4
Sensitivity / hurt feelings	0.7	1.2	2.8	1.2	-1.1	-0.4	-1.0	-0.9	-1.4	-0.0	-1.7
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.9	0.1	-0.4	0.3	-0.4	-0.4	-0.4	0.3	-0.9
Hearing difficulty/problems: Yes	0.9	1.4	3.4	-0.0	-0.9	-1.7	0.4	-1.2	-0.5	-1.8	-1.6
Relative age of first facial hair	1.4	2.9	7.5	-0.8	-1.7	-1.9	-2.0	-2.7	-1.4	-1.7	-0.4
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	6.9	-1.0	-0.9	-0.9	-2.6	-1.3	-1.0	-0.6	0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.7	-0.6	0.6	-0.4	0.1	-0.7	0.5	-0.4	0.9
Ever had hysterectomy (womb removed)	1.1	1.2	3.3	-0.2	-0.7	-1.8	1.1	-0.9	-0.8	-1.8	-0.5
Systolic blood pressure, automated reading	0.6	1.7	3.2	1.1	1.3	1.2	1.3	1.5	1.8	1.4	0.6
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	5.4	0.2	-1.0	-1.6	-2.3	-1.4	-1.1	-1.5	-1.0
Angina	1.0	1.3	9.5	-0.6	-0.4	-0.3	-3.1	0.2	-0.4	-0.3	0.2
Medication for hormone replacement therapy	1.6	1.8	8.6	-2.9	0.4	-0.9	0.4	-0.3	1.1	-1.1	1.3
Vitamin and mineral supplements	0.5	0.7	3.1	1.8	-0.3	0.4	0.3	-0.2	-0.8	0.6	-1.0
Supplements: Zinc	0.7	0.8	1.3	0.9	0.7	1.1	0.6	1.0	1.0	1.2	0.4
Medication: Co-codamol	0.4	0.5	2.8	-0.1	-0.5	-0.3	1.7	-0.6	-0.4	-0.4	0.1
Medication: Metformin	1.1	1.6	3.5	1.0	-1.7	-1.1	-0.1	-0.7	-1.7	-0.9	-1.9
Diabetes (father)	1.1	1.3	3.3	0.8	-1.6	-1.0	0.1	-0.8	-1.5	-0.7	-1.8
Diabetes (mother)	0.7	0.9	3.4	0.7	0.7	0.7	1.9	1.2	0.6	0.9	-0.1
Severe depression (siblings)	0.4	0.4	1.0	1.0	0.2	0.9	-0.5	-0.1	0.3	1.0	-0.4
Pack years adult smoking proportion	0.3	0.4	1.5	0.4	0.7	0.4	-0.0	0.5	0.7	0.2	1.2
Impedance of leg (right)	0.7	3.2	7.1	-1.1	-1.1	-2.5	-2.2	-2.0	-0.8	-2.7	0.5
Leg fat-free mass (left)	0.1	0.4	0.7	-0.4	-0.5	0.7	-0.5	-0.7	0.1	0.8	-0.8
Trunk fat percentage	0.8	3.0	6.2	-1.4	-2.0	-1.6	-2.0	-2.5	-1.4	-1.8	-0.3
Hand grip strength (right)	2.4	6.6	10.6	-0.0	-2.7	-3.2	-1.6	-2.3	-2.6	-3.3	-3.2
Townsend deprivation index at recruitment	0.5	0.6	1.5	-0.5	0.8	0.7	0.8	1.2	0.8	0.9	0.3
Current tobacco smoking	0.2	0.3	0.8	-0.8	0.0	-0.2	-0.1	-0.2	0.7	-0.3	0.9
Average weekly fortified wine intake	0.3	0.4	1.6	0.9	0.1	0.5	1.3	-0.1	0.4	0.2	-0.2
Maternal smoking around birth	0.7	1.1	4.1	-0.4	0.2	-1.0	-2.0	-1.1	0.4	-1.0	0.9
Fed-up feelings	0.9	1.6	3.2	-0.8	0.7	1.6	-1.6	1.8	0.5	1.6	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.7	0.2	-1.2	-1.2	-1.3	-0.8	-1.0	-0.8	-1.2
Relative age voice broke	0.2	0.3	1.2	-0.3	-0.5	0.1	-1.1	-0.7	-0.4	0.2	0.4
Taking other prescription medications	0.1	0.2	0.6	0.3	-0.4	-0.3	-0.8	-0.7	-0.3	-0.1	-0.5
Age when periods started (menarche)	5.7	13.6	22.7	2.1	-4.7	-3.9	-1.0	-3.8	-4.8	-3.5	-4.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	0.3	-0.7	-0.6	0.4	-0.6	-0.7	-0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	5.7	-0.6	-1.5	-1.3	2.4	-1.1	-1.4	-1.3	-1.1
Tinnitus: Yes, but not now, but have in the past	3.3	3.6	8.3	-2.1	-1.4	-2.6	-1.2	-1.9	-1.3	-2.9	-0.1
Qualifications: CSEs or equivalent	0.2	0.3	0.8	-0.0	0.5	0.7	-0.1	0.9	0.6	0.8	0.3
Serious illness, injury or assault to yourself	0.9	1.0	2.4	-0.3	-1.1	-0.8	-1.5	-0.8	-1.3	-1.0	-0.7
High blood pressure	0.2	0.6	2.4	1.6	0.2	0.2	0.8	0.1	0.4	0.1	-1.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	0.4	0.3	0.7	0.2	0.1	0.4	0.9	0.4
Multivitamins +/- minerals	0.2	0.3	0.7	-0.8	-0.5	-0.7	-0.1	-0.6	-0.3	-0.8	-0.2
Stomach or abdominal pain in last month	0.4	0.5	2.0	-0.4	-0.4	-0.7	-0.6	-1.4	-0.3	-0.8	-0.6
Supplements: Glucosamine	0.1	0.2	0.9	-0.9	-0.3	-0.2	0.1	-0.1	0.0	-0.4	0.6
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.8	-1.7	-0.4	-0.9	-0.8	-1.4	-0.4	-1.1	0.4
Medication: Atenolol	0.3	0.4	0.8	-0.8	-0.8	-0.5	-0.9	-0.5	-0.3	-0.4	-0.7
Medication: Levothyroxine sodium	0.5	0.9	1.6	-1.1	1.3	0.5	-0.6	0.5	1.2	0.7	1.1
Sitting height	0.4	2.8	7.1	-1.4	2.0	1.3	-0.9	0.4	2.7	1.0	2.4
Chronic bronchitis/emphysema (father)	1.1	1.3	3.6	-1.9	-0.6	-1.3	-1.3	-0.6	-0.5	-1.3	-0.7
High blood pressure (mother)	0.0	0.1	0.2	-0.1	-0.1	0.1	-0.0	-0.2	0.3	0.5	-0.4
Body mass index (BMI)	0.3	1.3	3.2	0.4	-1.8	-0.5	-1.0	-1.1	-1.6	-0.5	-1.4
Impedance of leg (left)	0.7	3.5	7.5	-1.1	-1.4	-2.6	-1.8	-2.4	-1.1	-2.7	0.5
Leg predicted mass (left)	0.1	0.4	0.7	-0.4	-0.5	0.8	-0.4	-0.6	0.2	0.9	-0.7
Trunk fat mass	0.7	2.9	6.4	-0.9	-2.2	-1.5	-1.9	-2.5	-1.5	-1.6	-0.9
Waist circumference	0.4	1.3	4.5	-0.6	-1.4	-0.3	-2.1	-1.5	-1.0	-0.2	-0.7
Number of incorrect matches in round	0.8	1.3	2.5	0.3	-1.5	-1.6	-0.0	-1.3	-1.1	-1.3	-1.1
Past tobacco smoking	0.6	1.2	7.0	0.8	0.4	0.7	2.6	0.7	-0.3	0.5	-0.4
Alcohol usually taken with meals	0.2	0.3	1.4	-0.2	0.3	-0.2	1.2	-0.3	0.3	-0.5	0.5
Nervous feelings	0.8	1.5	4.0	2.0	-1.1	-0.3	0.2	-0.6	-1.4	-0.2	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	1.9	0.1	-1.4	-0.4	-1.1	-1.4	-1.4	-0.1	-1.4
Hearing difficulty/problems with background noise	0.5	0.7	2.6	1.3	-0.5	-0.3	0.9	-0.6	-0.5	-0.1	-1.6
Hair/balding pattern: Pattern 2	0.2	0.3	0.9	-0.1	-0.3	-0.2	-0.9	0.9	-0.5	0.2	-0.4
Had menopause	0.1	0.2	0.9	0.9	0.2	-0.0	0.1	0.3	-0.0	0.1	-0.4
Had other major operations	3.3	4.0	6.7	0.1	-2.3	-2.6	-1.7	-1.8	-2.4	-2.5	-1.5
Forced vital capacity (FVC)	1.1	4.2	11.9	0.5	-2.0	-1.8	-2.0	-1.8	-2.1	-1.7	-3.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.6	-0.7	-1.1	-0.9	1.9	-1.4	-1.2	-0.9	-1.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.7	0.2	1.3	1.1	-0.6	0.6	1.1	1.0	0.2
Qualifications: None of the above	0.3	0.7	1.6	-0.8	-1.1	-0.8	0.7	-1.3	-0.8	-0.7	-0.4
Financial difficulties in last 2 years	0.6	0.8	2.3	-1.5	0.3	-1.0	-0.4	-0.5	0.4	-1.3	0.7
Mouth/teeth dental problems	1.5	2.3	4.3	0.4	2.1	1.5	1.8	1.8	1.7	1.1	0.8
Heart attack	0.7	1.0	4.4	-1.4	0.4	0.3	-2.1	0.1	0.4	0.2	0.9
Allergy	0.1	0.3	0.8	-0.6	0.1	-0.5	-0.5	-0.1	0.4	-0.9	0.6
Pain all over the body in last month	2.4	2.6	5.0	-0.8	-1.9	-2.2	-0.7	-1.4	-1.4	-2.2	-1.6
Diabetes (self-reported)	1.3	2.1	4.1	1.0	-1.8	-1.4	-0.6	-1.5	-2.0	-1.4	-1.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.5	0.4	0.0	-0.3	0.2	-0.7	-0.2	-0.2	-0.4
Medication: Ramipril	0.9	1.1	2.4	0.6	1.3	1.1	-0.8	1.6	1.2	0.9	0.6
Medication: Simvastatin	0.4	0.5	2.0	0.3	-0.9	-0.2	-1.4	-0.5	-0.6	-0.4	-0.8
Fluid intelligence score	0.9	1.9	3.9	-0.6	1.7	1.5	0.8	2.0	1.5	1.3	1.2
Illnesses of siblings	0.3	0.4	0.8	0.1	-0.6	-0.8	0.4	-0.9	-0.5	-0.8	-0.3
Neuroticism score	0.4	0.8	1.8	0.6	-1.0	-0.2	-1.4	-0.5	-1.3	0.0	-1.2
Weight	0.4	1.7	3.7	0.1	-1.8	-0.5	-1.8	-1.9	-1.2	-0.4	-1.4
Impedance of arm (right)	0.5	2.2	8.2	-2.2	1.2	0.1	-0.3	0.1	1.7	-0.1	2.9
Arm fat percentage (right)	0.2	0.9	1.9	-0.9	-1.4	-0.7	-1.1	-1.3	-0.9	-0.8	-0.3
Trunk fat-free mass	0.1	0.5	2.0	0.8	-0.5	0.7	-0.2	-0.5	0.0	0.9	-1.4
Hip circumference	0.2	0.7	1.1	1.1	-0.6	0.9	-0.9	-0.8	-0.4	1.0	-0.8
Time employed in main current job	0.5	0.6	1.9	0.8	-0.2	0.7	1.4	-0.3	-0.5	0.8	-1.0
Alcohol intake versus 10 years previously	0.2	0.3	0.8	-0.5	0.7	0.4	0.4	0.9	0.5	0.7	0.4
Father’s age at death	0.8	1.1	1.9	0.5	-0.9	-1.0	1.4	-1.0	-1.2	-1.1	-1.1
Worrier / anxious feelings	0.8	1.5	4.3	2.1	0.5	1.6	0.4	0.7	-0.1	2.0	-0.8
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	3.3	-0.9	-1.7	-1.7	-1.8	-1.7	-1.1	-1.5	-1.5
Falls in the last year	0.9	1.2	8.0	0.5	0.2	0.8	-2.8	0.1	0.1	0.8	-0.3
Hair/balding pattern: Pattern 3	0.2	0.2	0.9	1.0	0.1	-0.2	0.8	-0.4	-0.2	-0.1	-0.1
Number of live births	0.9	1.2	2.9	-0.5	-0.7	-1.4	-0.8	-1.7	-0.6	-1.5	-1.0
Forced expiratory volume in 1-second (FEV1)	1.5	5.0	8.8	-0.0	-2.5	-2.3	-1.0	-3.0	-2.4	-2.3	-2.8
Pulse rate	1.6	2.6	8.2	-0.4	-1.7	-1.9	-0.2	-2.9	-1.6	-1.8	-0.4
Happiness	1.2	1.4	4.4	1.3	-0.7	0.8	-2.1	-0.1	-1.0	1.2	-1.3
Noisy workplace	1.1	1.4	2.9	-0.6	-1.7	-1.5	1.0	-1.2	-0.9	-1.3	-0.7
Qualifications: A levels/AS levels or equivalent	0.4	1.0	3.0	-0.1	1.3	1.0	-0.0	1.7	1.1	0.8	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.1	-1.4	1.2	0.3	0.7	0.7	1.4	0.3	1.3
Mouth/teeth dental problems: Dentures	3.0	5.1	8.5	2.7	-2.8	-1.5	0.4	-2.4	-2.9	-1.0	-2.9
Asthma	0.2	0.3	1.3	0.1	0.0	0.3	1.1	0.1	-0.3	0.8	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.3	-0.5	-0.4	0.1	-0.8	-0.7	-0.4	0.2
Medication: Cholesterol lowering	0.5	0.8	1.8	0.1	0.8	1.3	-0.6	1.3	0.9	1.1	0.5
Depression (self-reported)	0.7	0.8	2.5	0.2	-1.0	-0.6	-1.6	-0.9	-0.9	-0.5	-1.0
Medication: Lansoprazole	1.0	1.1	7.0	-2.6	0.3	0.2	-0.2	-0.3	0.8	0.2	0.8
Prospective memory result	1.1	1.3	4.2	2.0	-0.3	1.4	0.8	0.8	-0.5	1.6	-0.6
Lung cancer (father)	1.0	1.1	2.5	-1.4	-0.7	-1.5	0.2	-1.1	-0.3	-1.6	0.6
Illnesses of mother	0.7	0.8	3.3	0.1	-1.0	-0.3	-0.9	-0.6	-1.8	-0.4	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	5.2	0.1	-1.7	-1.3	-1.1	-2.3	-1.7	-1.4	-1.9
Pulse wave Arterial Stiffness index	1.8	2.1	6.4	0.2	1.1	1.4	2.5	1.0	1.5	1.3	1.6
Impedance of arm (left)	0.4	1.8	6.7	-2.0	1.2	-0.1	-0.2	-0.0	1.4	-0.3	2.6
Arm fat mass (right)	0.4	1.6	2.9	-0.7	-1.7	-0.8	-1.6	-1.7	-1.2	-0.9	-0.9
Trunk predicted mass	0.1	0.5	1.9	0.7	-0.5	0.6	-0.2	-0.5	0.0	0.9	-1.4
Standing height	0.1	0.9	3.7	-0.7	-0.3	-0.2	-1.6	-1.9	0.6	-0.1	-0.2
Length of working week for main job	0.4	0.4	1.1	1.0	0.4	0.7	-0.4	0.9	0.2	0.6	0.3
Exposure to tobacco smoke at home	0.5	0.5	1.8	-0.6	-0.6	-0.6	-1.4	-0.8	-0.2	-0.6	-0.4
Breastfed as a baby	0.6	0.8	1.8	-0.8	-0.7	-0.9	0.9	-1.3	-0.7	-1.0	0.1
Tense / ‘highly strung’	0.3	0.4	1.0	1.0	-0.7	-0.4	-0.4	-0.5	-0.6	-0.3	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	7.4	1.6	1.2	2.5	-0.2	1.0	1.0	2.7	-0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.6	0.1	-0.2	-0.4	0.8	-0.3	0.2	-0.7	-0.3
Birth weight of first child	1.2	2.2	3.6	-0.1	-1.9	-1.7	1.3	-1.5	-1.7	-1.5	-1.4
Peak expiratory flow (PEF)	1.5	3.5	8.8	-1.8	-1.8	-2.1	-0.7	-3.0	-1.6	-2.3	-0.2
Pulse wave reflection index	0.4	0.4	0.8	-0.9	0.6	0.1	0.9	0.3	0.9	-0.0	0.8
Ever highly irritable/argumentative for 2 days	0.7	0.9	1.6	0.5	1.3	0.9	-0.9	1.3	0.8	0.6	0.9
Loud music exposure frequency	1.5	1.7	5.3	-2.3	0.1	-1.5	-1.5	0.9	0.1	-1.6	0.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.4	-0.3	1.3	0.6	0.1	1.9	1.1	0.6	0.6
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	4.9	-2.0	0.8	0.8	-1.0	0.3	1.1	0.8	2.2
Blood clot in the leg (DVT)	2.3	3.0	7.5	1.1	-2.1	-0.8	-1.7	-1.0	-2.4	-0.8	-2.7
Medication: Paracetamol	0.8	1.3	3.3	-1.0	-1.1	-1.7	0.4	-1.1	-0.7	-1.8	-0.4
Headache pain in last month	0.3	0.6	1.6	0.3	-0.4	-0.8	1.1	-1.3	-0.6	-0.8	0.2
Medication for cholesterol, blood pressure or diabetes	0.5	0.7	1.2	-0.6	-0.5	-1.1	1.1	-1.1	-0.8	-1.1	0.2
Glaucoma (self-reported)	0.3	0.3	0.8	-0.7	-0.1	-0.7	-0.1	-0.9	0.2	-0.7	0.3
Gout (self-reported)	1.8	2.4	7.2	-1.1	2.0	0.9	-0.5	1.3	2.7	0.9	1.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	5.6	-1.1	0.1	-0.8	-2.4	-0.5	0.2	-0.6	0.3
Medication: Amlodipine	0.3	0.4	2.1	-0.0	-0.3	-0.7	1.5	-0.3	-0.2	-0.7	-0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.6	2.0	0.5	0.4	0.5	1.4	1.1	-0.1	0.6	-0.2
Birth weight	0.8	1.8	3.1	0.1	-1.5	-1.6	-0.8	-1.8	-1.3	-1.4	-1.4
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.0	-0.5	-0.1	-0.6	-1.0	-0.6	0.5	-0.5	-0.0
High blood pressure (siblings)	0.7	1.0	2.5	0.2	1.0	1.3	-0.4	1.6	0.8	1.2	0.6
Forced vital capacity (FVC), Best measure	0.6	2.1	7.0	0.6	-1.2	-0.8	-2.0	-1.1	-1.4	-0.7	-2.6
Body fat percentage	0.9	3.4	6.4	-0.9	-2.4	-1.7	-2.1	-2.5	-1.8	-1.8	-0.8
Leg fat percentage (right)	1.2	4.4	7.4	-0.1	-2.7	-1.9	-2.4	-2.5	-2.3	-2.0	-1.5
Arm fat-free mass (right)	0.3	1.4	3.1	0.2	-1.5	-0.3	-1.4	-1.6	-1.1	-0.1	-1.8
Exposure to tobacco smoke outside home	1.1	1.4	5.4	-1.9	-0.3	-0.8	-2.3	-1.0	0.1	-0.6	-0.1
Comparative body size at age 10	0.5	1.3	4.5	1.1	-1.4	0.2	-0.5	-0.1	-1.5	0.2	-2.1
Number of full brothers	2.4	3.1	6.7	-1.5	-1.2	-2.4	-1.8	-2.1	-0.9	-2.6	-0.3
Worry too long after embarrassment	1.0	1.7	5.4	1.2	-1.2	-0.6	-2.3	-0.2	-1.4	-0.6	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	2.6	0.7	0.6	1.6	-1.2	0.5	0.7	1.5	0.4
Wheeze or whistling in the chest in last year	1.2	2.1	8.1	-2.9	-1.3	-1.4	-1.4	-1.0	-0.9	-1.3	-0.2
Number of children fathered	0.3	0.4	1.5	-1.0	0.0	0.4	0.5	-0.3	-0.0	0.1	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.2	-1.0	0.3	-0.5	-1.5	-0.3	0.7	-0.6	1.1
Age at first live birth	0.5	0.9	2.2	0.2	-0.7	-1.2	-0.3	-0.6	-0.7	-1.5	-1.3
Pulse wave peak to peak time	1.5	1.8	7.1	-0.3	-0.9	-1.1	-2.7	-0.8	-1.2	-1.0	-1.3
Health satisfaction	2.1	2.7	15.4	-1.2	-0.6	-0.5	-3.9	-1.8	-0.6	-0.4	-0.7
Shortness of breath walking on level ground	0.5	0.6	3.2	0.3	-0.3	-0.5	-1.8	0.3	-0.4	-0.5	-1.0
Qualifications: College or University degree	1.5	4.8	8.8	-1.1	2.6	2.0	0.4	2.8	2.8	1.4	3.0
Eye problems/disorders: None of the above	1.5	1.7	3.5	-0.9	1.2	1.9	0.5	1.3	0.9	1.9	1.2
Mouth/teeth dental problems: Loose teeth	1.4	1.7	5.8	-2.3	0.2	0.8	-2.4	-0.1	0.5	0.4	1.3
Emphysema/chronic bronchitis	1.0	1.1	4.6	-2.2	1.2	0.7	-0.2	0.1	1.2	0.7	0.9
Medication for pain relief, constipation, heartburn	1.2	2.1	3.6	0.3	1.8	1.9	-0.4	1.8	1.4	1.8	1.1
Neck or shoulder pain in last month	1.4	2.0	3.5	-1.2	-1.6	-1.9	-0.8	-1.7	-1.4	-1.7	-0.2
Medication: Blood pressure	0.4	0.6	1.7	1.1	-0.1	0.7	-1.3	0.6	0.4	0.7	-0.9
Angina (self-reported)	0.9	1.2	8.9	-0.4	-0.4	-0.3	-3.0	0.3	-0.5	-0.3	0.1
Migraine (self-reported)	1.7	2.1	9.6	-0.7	0.3	-0.8	3.1	-0.4	1.2	-0.9	1.9
Medication: Ibuprofen	0.4	0.4	1.1	1.1	-0.6	-0.1	-1.0	-0.6	-0.9	0.0	-0.1
Medication: Allopurinol	0.2	0.3	0.8	-0.4	0.2	-0.7	-0.9	-0.3	0.8	-0.6	-0.1
Medication: Omeprazole	1.7	2.0	3.5	1.0	-1.5	-1.4	-0.6	-1.5	-1.7	-1.3	-1.9
Medication: Seretide 50 evohaler	0.6	0.7	1.1	-0.6	1.0	0.7	0.8	0.4	0.9	1.0	1.0
Mean time to correctly identify matches	0.6	1.2	5.1	2.3	0.6	1.1	1.0	0.6	0.4	1.2	-0.2
Heart disease (mother)	3.0	3.7	6.2	-0.9	2.4	1.9	0.3	2.2	2.5	1.8	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.7	4.4	9.7	-2.0	-1.2	-3.1	-1.7	-2.7	-0.8	-3.0	-0.5
Whole body fat mass	0.8	3.3	6.6	-0.6	-2.3	-1.6	-2.0	-2.6	-1.7	-1.7	-1.2
Leg fat mass (right)	1.1	4.2	8.0	-0.0	-2.8	-1.6	-2.2	-2.6	-2.3	-1.7	-1.8
Arm predicted mass (right)	0.2	1.3	3.3	0.4	-1.4	-0.3	-1.3	-1.5	-0.9	-0.1	-1.8
Pulse rate, automated reading	1.0	3.2	10.6	-0.7	-1.7	-2.0	0.6	-3.3	-1.6	-2.1	0.7
Alcohol intake frequency.	0.5	1.1	2.6	1.6	0.1	0.9	1.6	0.8	-0.5	1.0	-1.0
Comparative height size at age 10	0.2	1.2	2.8	-1.3	0.8	0.9	-1.6	0.4	1.7	1.1	0.2
Number of full sisters	0.2	0.3	1.6	-0.0	-0.2	-0.0	1.3	-0.1	0.5	0.2	0.5
Suffer from ‘nerves’	1.3	2.1	5.8	1.1	-1.8	-1.0	-0.2	-1.4	-1.9	-0.6	-2.4
Overall health rating	2.4	5.2	12.5	-2.4	-2.1	-1.9	-3.5	-2.4	-1.7	-1.9	-1.6
Chest pain or discomfort	0.7	0.9	1.9	-0.3	-1.3	-1.0	-0.6	-1.2	-1.4	-0.8	-0.6
Had major operations	0.4	0.4	2.5	0.3	-0.4	0.2	-1.6	-0.6	-0.6	0.1	-0.1
Age at last live birth	0.4	0.5	1.8	-0.2	-0.2	-1.1	0.1	-0.5	-0.4	-1.3	-0.9
Family relationship satisfaction	1.8	2.3	4.7	1.2	1.6	2.2	-0.8	1.1	1.5	2.0	1.2
Leg pain on walking	0.2	0.3	0.6	0.8	-0.7	-0.3	0.3	0.0	-0.6	-0.4	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.8	-0.5	0.1	-0.5	-1.7	0.7	0.0	-0.2	-0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.0	-0.8	0.7	0.0	-0.6	0.2	1.0	0.2	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.6	1.2	-0.3	0.4	1.0	-0.2	-0.1	0.4	-0.0
Medication: Aspirin	0.2	0.2	1.1	0.2	-0.5	-0.4	-0.1	-1.1	-0.4	-0.4	-0.1
Supplements: Vitamin C	0.3	0.3	0.8	-0.9	0.2	-0.5	-0.1	0.3	0.7	-0.6	0.6
Knee pain experienced in last month	0.3	0.5	3.1	-1.7	0.1	-0.2	-0.2	0.1	0.5	-0.4	0.6
Hypertension (Self-reported)	0.3	0.8	3.3	1.8	0.2	0.6	1.0	0.5	0.5	0.4	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	6.5	-1.5	-0.5	-1.2	-2.5	-1.0	-0.4	-1.5	0.2
Illnesses of father: Heart disease	1.6	2.2	4.0	0.3	2.0	1.8	-0.4	1.9	1.6	1.6	1.0
Illnesses of siblings: Diabetes	0.0	0.0	0.1	0.1	0.2	-0.2	0.0	-0.1	0.3	-0.2	-0.3
Smoking status: Previous	0.9	1.3	8.2	-1.1	0.2	-0.1	-2.9	0.1	0.8	0.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	5.4	-2.3	0.3	0.4	-1.2	-0.5	0.7	0.1	0.6
Whole body fat-free mass	0.1	0.4	1.3	0.1	-0.6	0.6	-0.4	-0.7	-0.0	0.8	-1.1
Leg fat-free mass (right)	0.1	0.4	0.9	-0.5	-0.4	0.8	-0.2	-0.7	0.1	0.9	-0.8
Arm fat percentage (left)	0.2	1.0	1.9	-0.8	-1.4	-0.6	-1.0	-1.4	-1.0	-0.8	-0.3
Average weekly red wine intake	0.4	0.6	2.0	-0.4	-0.5	-0.9	-1.4	-0.2	-0.6	-1.2	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.3	0.8	0.1	-0.0	0.2	0.9	-0.0	0.4
Mood swings	0.3	0.5	1.3	0.6	-0.8	0.1	-0.8	0.0	-1.1	0.5	-0.7
Loneliness, isolation	0.3	0.4	1.9	-0.3	0.4	0.6	0.1	1.4	0.5	0.7	-0.3
Long-standing illness, disability or infirmity	0.7	1.0	5.3	-0.8	-0.1	-0.8	-2.3	-0.9	0.2	-0.9	-0.4
Ever had bowel cancer screening	1.9	2.3	3.4	1.3	-1.8	-1.8	0.9	-1.2	-1.7	-1.4	-1.6
Diabetes diagnosed by doctor	1.5	2.5	4.3	0.9	-1.9	-1.3	-0.9	-1.7	-2.1	-1.2	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.2	-0.6	0.7	0.5	-0.3	0.2	1.2	0.3	1.5
Friendships satisfaction	0.5	0.6	1.3	0.7	0.5	-0.8	-0.2	-1.1	0.5	-1.0	-0.9
Qualifications: nursing, teaching	2.1	3.2	4.7	-1.2	2.2	2.2	0.5	2.1	2.0	1.7	1.8
Commuting to job workplace: Walk	2.1	2.3	7.7	-0.1	0.7	1.1	2.7	2.8	0.8	1.1	-0.3
Eye problems/disorders: Cataract	0.5	0.5	1.0	0.2	-0.6	-0.9	-0.9	-0.4	-0.6	-1.0	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	2.2	-0.3	-1.3	-1.5	-1.4	-0.7	-1.3	-1.1	-0.7
Medication for cholesterol	0.4	0.6	1.6	1.3	-0.7	-0.1	-1.1	0.0	-0.9	0.3	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.3	0.5	0.2	-0.2	0.4	0.3	-0.1	-0.0	-0.5
Back pain experienced in last month	0.9	1.2	2.3	-0.9	1.3	1.2	-0.2	1.2	1.2	1.0	1.5
Mineral and other dietary supplements	0.3	0.4	1.0	0.7	0.7	0.6	1.0	0.5	0.5	0.6	-0.2
Breast cancer (self-reported)	0.7	0.9	1.9	-1.1	0.1	-1.2	1.1	0.1	0.8	-1.4	0.7
Asthma (self-reported)	0.2	0.4	1.3	0.0	-0.0	0.4	1.1	0.2	-0.3	0.9	-0.7
Osteoporosis (self-reported)	0.7	0.8	2.8	1.2	0.7	0.2	1.7	1.3	0.1	-0.1	0.2
Osteoarthritis (self-reported)	0.6	0.8	2.1	-0.1	0.8	1.2	1.5	0.6	0.4	1.2	0.7
Medication: Aspirin	0.5	0.6	1.4	0.7	-0.7	-0.7	-0.8	-1.2	-0.7	-0.7	-0.5
Medication: Gliclazide	0.6	0.7	4.3	-0.4	0.0	-0.5	2.1	0.3	0.5	-0.6	0.2
Illnesses of father: None of the above (group 1)	1.0	1.3	2.7	-0.9	-1.2	-1.7	0.9	-1.5	-0.5	-1.4	0.2
Smoking status: Current	0.1	0.1	0.3	-0.2	-0.3	-0.3	-0.1	-0.6	0.3	-0.3	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	5.8	0.6	-1.9	-1.5	-0.2	-2.2	-2.2	-1.3	-2.4
Whole body water mass	0.1	0.5	1.8	0.2	-0.7	0.4	-0.5	-0.8	-0.2	0.7	-1.3
Leg predicted mass (right)	0.1	0.4	1.1	-0.5	-0.3	0.9	-0.1	-0.6	0.3	1.1	-0.6
Arm fat mass (left)	0.3	1.3	2.5	-0.5	-1.6	-0.7	-1.4	-1.6	-1.1	-0.7	-0.9
Number of self-reported non-cancer illnesses	0.1	0.1	0.3	0.1	0.3	-0.2	-0.6	-0.4	0.2	-0.1	0.3
Average weekly champagne plus white wine intake	0.8	1.1	3.8	-1.3	0.7	0.2	1.0	-0.2	1.2	0.0	1.9
Miserableness	0.2	0.3	0.8	-0.1	0.4	0.7	-0.3	0.9	0.3	0.9	0.0
Guilty feelings	0.3	0.5	1.1	0.9	-0.5	0.2	0.9	-0.3	-0.5	0.4	-1.0
Wears glasses or contact lenses	0.2	0.2	0.8	0.6	0.5	0.3	0.9	0.5	0.2	0.2	0.2
Ever taken oral contraceptive pill	1.2	1.3	3.2	-1.8	1.1	0.3	0.9	0.6	1.6	0.1	1.4
Hearing aid user	0.3	0.3	1.3	-1.1	-0.6	0.4	0.2	-0.3	-0.4	0.8	0.1
Mother’s age at death	2.5	3.1	6.4	1.6	-2.2	-1.4	0.5	-1.6	-2.5	-1.3	-2.1
Financial situation satisfaction	0.7	0.9	2.9	-0.5	0.8	1.4	-1.0	0.1	0.8	1.7	0.3
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.0	-0.7	-0.9	-0.3	-0.2	-1.4	-0.5	-0.1	-1.2
Commuting to job workplace: Public transport	1.4	1.7	3.6	1.9	1.2	1.7	1.3	0.5	0.6	1.5	0.9
Eye problems/disorders: Glaucoma	0.4	0.5	1.4	-0.6	-0.7	-0.8	-0.3	-1.2	-0.3	-0.8	0.1
Medication: Blood pressure	0.4	0.7	2.1	-0.2	1.2	0.8	0.9	0.7	1.4	0.3	0.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.8	0.2	-0.7	-1.2	-1.3	-0.7	-0.5	-1.3	-0.9
Supplements: Fish oil (including cod liver oil)	1.2	1.5	2.5	-0.7	-1.4	-1.5	-1.6	-1.3	-1.2	-1.2	-0.6
High cholesterol (Self-reported)	0.3	0.6	3.9	0.7	-0.4	0.4	-2.0	-0.1	-0.3	0.3	-0.1
Medication: Bendroflumethiazide	1.2	1.9	4.9	0.7	1.6	1.3	1.3	2.2	1.5	1.1	0.3
Medication: Paracetamol	0.5	0.8	1.9	-0.8	-0.7	-1.3	-0.3	-1.3	-0.6	-1.4	-0.1
Medication: Lisinopril	0.2	0.3	0.9	-0.9	-0.5	-0.5	-0.1	-0.8	0.2	-0.6	0.2
Medication: Atorvastatin	1.5	1.8	2.9	-1.4	1.7	1.1	-1.5	0.7	1.5	1.0	1.6
Illnesses of father: High blood pressure	0.2	0.3	0.8	0.3	0.9	0.7	-0.0	0.3	0.6	0.6	0.2
Alcohol drinker status: Never	0.3	0.4	0.9	0.3	0.3	0.9	-0.1	0.2	0.2	0.9	1.0
Ever smoked	0.2	0.4	1.6	-0.1	-0.4	-0.5	-1.3	-0.2	0.5	-0.4	0.7
Basal metabolic rate	0.1	0.6	1.6	0.1	-0.9	0.3	-0.8	-1.1	-0.3	0.5	-1.3
Leg fat percentage (left)	1.3	4.7	8.3	-0.0	-2.9	-1.9	-2.3	-2.7	-2.4	-2.0	-1.6
Arm fat-free mass (left)	0.2	1.2	2.4	0.2	-1.3	-0.4	-1.4	-1.5	-0.8	-0.3	-1.6
Number of operations (self-reported)	3.6	5.4	8.7	-1.1	-2.2	-2.9	-2.1	-3.0	-2.3	-3.0	-0.9
Average weekly beer plus cider intake	0.3	0.5	1.8	0.7	-0.7	0.1	-1.4	-0.7	-0.3	-0.1	-0.5
Irritability	0.1	0.2	1.5	1.2	0.3	0.2	-0.2	0.3	-0.2	0.1	-0.2
Risk taking	2.0	2.9	7.0	-2.6	-0.7	-2.0	-2.5	-0.9	-0.2	-2.0	0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.1	0.3	0.0	0.6	1.4	-0.7	0.2	0.7	0.6
Fractured/broken bones in last 5 years	0.8	1.0	2.8	-1.7	-0.1	-1.1	-0.5	-0.8	0.5	-1.4	0.9
Age started oral contraceptive pill	1.0	1.3	2.2	0.9	-1.0	-1.4	0.4	-0.8	-1.1	-1.4	-1.5
Diastolic blood pressure, automated reading	1.2	3.7	6.0	-0.2	2.0	2.3	-2.5	2.0	2.1	2.3	0.7
Ever depressed for a whole week	0.6	0.7	1.5	0.3	1.0	1.1	-0.3	0.8	0.9	1.2	0.8
Unable to work because of sickness or disability	0.6	0.8	2.0	-0.3	-1.0	-0.6	-1.4	-0.6	-1.0	-0.5	-1.3
Commuting to job workplace: Cycle	0.4	0.5	1.2	0.3	0.7	0.9	0.8	0.7	1.1	0.7	-0.2
Myopia	0.5	0.7	2.3	-0.0	0.9	-0.1	-1.5	0.6	1.2	-0.5	0.9
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.0	-1.0	-0.8	-0.8	-0.6	-0.8	-0.9	-0.7	0.5
Cholesterol lowering medication	0.3	0.5	1.4	-1.2	-0.1	-0.4	-1.0	-0.6	0.0	-0.6	0.9
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	2.5	0.1	-1.6	-1.5	-0.5	-1.5	-1.3	-1.5	-1.6
Pain experienced in last month	0.3	0.5	1.8	1.3	0.1	0.9	-0.3	0.9	-0.1	0.8	-0.6
Supplements: Calcium	2.5	2.7	5.3	-0.4	1.8	2.1	0.2	2.3	1.2	1.9	1.9
Basal cell carcinoma (self-reported)	0.3	0.3	0.7	0.7	0.6	0.6	-0.3	0.8	0.2	0.7	0.2
Heart attack/myocardial infarction (self-reported)	0.8	1.0	5.6	-1.2	0.2	0.2	-2.4	0.0	0.3	0.1	0.7
Deep venous thrombosis (DVT) (self-reported)	1.6	2.0	5.3	1.1	-1.6	-0.4	-1.5	-0.6	-1.9	-0.4	-2.3
Heart disease (siblings)	0.5	0.6	1.5	0.4	0.2	1.2	-0.9	1.0	-0.1	1.1	-0.1
Alcohol drinker status: Previous	1.3	1.5	2.4	0.8	-1.1	-1.2	-1.6	-1.0	-1.3	-1.1	-1.5
Pack years of smoking	0.3	0.4	1.2	0.6	0.6	0.6	-0.0	0.5	0.6	0.4	1.1
Impedance of whole body	0.4	2.0	4.1	-2.0	-0.0	-1.3	-1.2	-1.5	0.3	-1.6	2.0
Leg fat mass (left)	1.2	4.7	8.9	0.0	-3.0	-1.7	-2.4	-2.7	-2.4	-1.7	-2.0
Arm predicted mass (left)	0.3	1.5	3.1	0.2	-1.7	-0.5	-1.1	-1.7	-1.1	-0.3	-1.8