[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:149,787,068-151,886,485

Best TWAS P=4.52e-22 · Best GWAS P=4.5e-23 conditioned to 0.00681

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa GM2A 0.18 0.08 lasso 6 0.10 4.8e-07 6.6 5.3 1.0e-07 -0.22 0.99 0.00 FALSE
2 GTEx Esophagus Muscularis GM2A 0.24 0.22 lasso 3 0.24 1.6e-14 -8.5 -8.4 4.5e-17 0.18 1.00 0.00 FALSE
3 GTEx Heart Atrial Appendage GM2A 0.23 0.31 lasso 2 0.29 2.3e-13 -8.5 -8.5 2.4e-17 0.20 1.00 0.00 FALSE
4 GTEx Heart Left Ventricle GM2A 0.39 0.33 lasso 3 0.33 2.2e-18 -8.5 -8.4 2.9e-17 0.21 1.00 0.00 FALSE
5 GTEx Heart Left Ventricle ANXA6 0.22 0.01 lasso 4 0.12 1.0e-06 -8.5 8.5 1.5e-17 -0.24 0.84 0.02 FALSE
6 GTEx Liver G3BP1 0.35 0.05 lasso 6 0.05 1.7e-02 -4.4 5.3 1.0e-07 -0.18 0.06 0.62 TRUE
7 GTEx Whole Blood GM2A 0.56 0.44 lasso 4 0.44 1.3e-43 -8.5 -8.1 8.4e-16 0.19 1.00 0.00 FALSE
8 GTEx Whole Blood CCDC69 0.13 0.03 enet 11 0.04 1.3e-04 -9.9 6.9 5.9e-12 -0.71 0.00 0.97 TRUE
9 NTR Blood GM2A 0.52 0.36 enet 28 0.38 4.2e-131 -8.5 -9.7 4.5e-22 0.24 1.00 0.00 TRUE
10 ROSMAP Brain Pre-frontal Cortex CCDC69 0.08 0.07 bslmm 611 0.06 2.9e-08 -8.5 -7.7 1.5e-14 0.23 0.00 1.00 FALSE
11 YFS Blood GM2A 0.61 0.32 enet 55 0.38 1.5e-131 -8.5 -8.6 7.1e-18 0.22 1.00 0.00 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC69 0.06 0.00 blup 91 0.01 2.6e-02 4.4 -6.4 1.5e-10 0.41 0.02 0.06 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma GM2A 0.08 0.00 blup 327 0.04 1.0e-04 -3.4 6.0 2.6e-09 -0.12 0.10 0.38 FALSE