[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:149,787,068-151,886,485

Best TWAS P=4.52e-22 · Best GWAS P=4.5e-23 conditioned to 0.00681

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	NTR	Blood	GM2A	0.52	0.36	enet	28	0.38	4.2e-131	-8.5	-9.7	4.5e-22	0.24	1.00	0.00	TRUE
8	GTEx	Whole Blood	CCDC69	0.13	0.03	enet	11	0.04	1.3e-04	-9.9	6.9	5.9e-12	-0.71	0.00	0.97	TRUE
6	GTEx	Liver	G3BP1	0.35	0.05	lasso	6	0.05	1.7e-02	-4.4	5.3	1.0e-07	-0.18	0.06	0.62	TRUE
11	YFS	Blood	GM2A	0.61	0.32	enet	55	0.38	1.5e-131	-8.5	-8.6	7.1e-18	0.22	1.00	0.00	FALSE
5	GTEx	Heart Left Ventricle	ANXA6	0.22	0.01	lasso	4	0.12	1.0e-06	-8.5	8.5	1.5e-17	-0.24	0.84	0.02	FALSE
3	GTEx	Heart Atrial Appendage	GM2A	0.23	0.31	lasso	2	0.29	2.3e-13	-8.5	-8.5	2.4e-17	0.20	1.00	0.00	FALSE
4	GTEx	Heart Left Ventricle	GM2A	0.39	0.33	lasso	3	0.33	2.2e-18	-8.5	-8.4	2.9e-17	0.21	1.00	0.00	FALSE
2	GTEx	Esophagus Muscularis	GM2A	0.24	0.22	lasso	3	0.24	1.6e-14	-8.5	-8.4	4.5e-17	0.18	1.00	0.00	FALSE
7	GTEx	Whole Blood	GM2A	0.56	0.44	lasso	4	0.44	1.3e-43	-8.5	-8.1	8.4e-16	0.19	1.00	0.00	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	CCDC69	0.08	0.07	bslmm	611	0.06	2.9e-08	-8.5	-7.7	1.5e-14	0.23	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	CCDC69	0.06	0.00	blup	91	0.01	2.6e-02	4.4	-6.4	1.5e-10	0.41	0.02	0.06	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	GM2A	0.08	0.00	blup	327	0.04	1.0e-04	-3.4	6.0	2.6e-09	-0.12	0.10	0.38	FALSE
1	GTEx	Esophagus Mucosa	GM2A	0.18	0.08	lasso	6	0.10	4.8e-07	6.6	5.3	1.0e-07	-0.22	0.99	0.00	FALSE