TWAS hub - ANXA6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1660	0.0360	4.7e-07	0.058	0.047	0.084	0.060	0.056	1.2e-07	2.2e-06	1.9e-10	8.3e-08	1.9e-07
2	GTEx	Artery Tibial	0.2514	0.0553	6.6e-06	0.175	NA	0.128	NA	0.168	1.1e-13	NA	3.2e-10	NA	3.8e-13
3	GTEx	Esophagus Muscularis	0.2490	0.0710	4.2e-04	0.071	NA	0.106	NA	0.106	4.1e-05	NA	5.3e-07	NA	6.0e-07
4	GTEx	Heart Left Ventricle	0.2178	0.0740	1.5e-03	0.012	NA	0.091	NA	0.115	6.9e-02	NA	1.4e-05	NA	1.0e-06
5	NTR	Blood	0.0954	0.0220	4.0e-09	0.023	0.029	0.049	0.032	0.037	4.1e-08	6.9e-10	2.1e-15	1.1e-10	4.1e-12
6	ROSMAP	Brain Pre-frontal Cortex	0.0903	0.0349	9.0e-03	0.058	0.017	0.052	0.035	0.019	6.2e-08	2.3e-03	2.4e-07	2.1e-05	1.5e-03
7	YFS	Blood	0.3131	0.0322	0.0e+00	0.189	0.192	0.222	0.223	0.226	1.3e-59	1.8e-60	7.2e-71	3.1e-71	1.5e-72
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0606	0.0267	8.4e-03	-0.002	0.012	0.000	NA	0.002	7.3e-01	1.6e-02	3.4e-01	NA	1.6e-01
9	TCGA	Pheochromocytoma and Paraganglioma	0.1560	0.0690	6.8e-03	0.111	0.022	0.028	NA	0.070	3.6e-05	4.5e-02	2.8e-02	NA	1.0e-03
10	TCGA	Prostate Adenocarcinoma	0.1080	0.0326	1.2e-06	0.097	0.082	0.075	NA	0.091	2.6e-10	6.9e-09	2.8e-08	NA	8.4e-10
11	TCGA	Testicular Germ Cell Tumors	0.1940	0.0690	7.4e-04	0.023	0.075	0.037	NA	0.021	5.2e-02	1.2e-03	1.8e-02	NA	5.8e-02
12	TCGA	Thyroid Carcinoma	0.0610	0.0280	9.7e-03	-0.001	0.008	0.000	NA	-0.001	3.8e-01	4.6e-02	3.0e-01	NA	3.7e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Crohns Disease (2012)	8.3	13.3	43.0	4.0	3.6	4.0	1.9	6.6	4.0	3.8	1.9	3.5	3.5	3.1	0.7
Crohns Disease (2017)	4.9	10.7	36.2	4.0	3.3	3.2	2.0	6.0	3.6	3.1	0.6	3.2	3.2	2.5	0.8
Relative age voice broke	3.7	5.6	10.5	2.3	2.7	2.5	1.7	2.7	3.0	3.2	1.3	2.5	2.7	1.2	1.6
Diabetes (mother)	3.6	4.6	9.3	-2.3	-2.6	-2.3	-3.0	-0.0	-2.6	-2.0	-0.5	-2.7	-2.6	0.1	-1.8
Birth weight of first child	3.6	6.6	11.7	-2.1	-2.8	-3.4	-2.1	-2.3	-2.8	-2.8	-2.4	-2.8	-2.8	-1.9	-2.1
Comparative body size at age 10	3.4	9.4	19.3	-3.7	-3.2	-2.9	-2.2	-2.4	-4.0	-4.4	-1.7	-3.3	-3.0	-1.6	-2.9
Prospective memory result	3.2	3.9	7.8	1.7	2.1	2.3	1.7	2.2	1.7	1.9	2.8	2.3	2.2	1.3	-0.0
Number of live births	3.1	4.4	7.7	-2.6	-2.6	-1.9	-0.1	-0.5	-2.6	-2.2	-2.6	-2.8	-2.6	-1.2	-1.1
Osteoporosis (self-reported)	3.0	3.7	6.7	1.9	2.5	2.0	0.2	1.5	2.2	1.6	2.2	2.6	2.5	1.9	-0.3
Irritable Bowel Disease (IBD)	2.9	6.8	23.2	3.2	2.4	2.2	2.4	4.8	3.0	3.1	1.3	2.1	2.3	1.2	0.2
LDL Cholesterol	2.8	4.5	11.6	-1.9	-2.5	-2.5	-0.4	-1.1	-1.9	-2.1	-1.4	-2.3	-2.5	-1.9	-3.4
Breast cancer (self-reported)	2.6	3.1	9.0	-1.6	-1.8	-1.8	-3.0	-0.8	-1.7	-1.9	-2.2	-1.7	-1.8	-0.8	-1.0
HDL Cholesterol	2.5	4.1	7.5	-1.2	-2.6	-2.5	-1.0	-1.8	-2.3	-2.2	-2.2	-2.7	-2.6	-1.3	-0.1
Ever used hormone-replacement therapy (HRT)	2.5	3.2	8.6	-2.9	-2.0	-1.8	-0.4	-1.7	-1.9	-1.8	-0.3	-2.1	-1.9	-2.0	-1.1
Loud music exposure frequency	2.4	2.6	5.6	-0.6	1.9	2.4	1.4	0.3	2.1	1.6	2.1	1.8	1.9	0.6	-0.9
Had major operations	2.4	2.8	5.2	-1.5	-2.3	-2.2	-0.0	-1.2	-1.9	-1.2	-0.9	-2.0	-2.2	-2.3	0.1
Rheumatoid Arthritis	2.3	3.2	7.5	2.7	2.1	2.1	2.0	1.4	1.7	1.0	-0.3	1.8	2.0	1.6	1.7
Age when periods started (menarche)	2.3	5.4	14.6	3.8	2.2	2.1	1.6	2.9	2.6	2.6	0.6	2.3	2.2	1.3	2.1
Supplements: Glucosamine	2.3	3.1	6.6	-2.1	-1.4	-1.4	-1.9	-1.4	-1.9	-2.6	-2.1	-1.6	-1.5	-1.2	-1.3
Medication: Simvastatin	2.3	3.3	5.1	1.3	2.2	2.2	1.5	1.9	2.0	1.6	1.8	2.0	2.2	2.0	0.6
Average weekly spirits intake	2.1	2.6	7.5	-1.3	-1.0	-0.3	-2.5	-1.7	-2.1	-2.7	-2.2	-1.0	-0.8	-0.7	-0.2
Average weekly fortified wine intake	2.1	2.4	6.1	-1.2	-1.8	-2.5	-0.1	-0.8	-1.7	-1.9	-1.4	-1.9	-1.8	-1.6	-0.6
Alcohol drinker status: Never	2.1	2.5	4.3	1.8	1.4	1.5	1.4	2.1	1.5	2.1	1.7	1.3	1.5	1.1	1.1
Illnesses of father: Heart disease	2.0	2.8	5.0	2.1	1.7	1.3	2.1	1.4	2.2	1.7	1.0	1.6	1.5	1.7	1.2
Length of working week for main job	1.9	2.1	7.1	-1.2	-1.1	-2.1	-0.9	-1.9	-0.7	-0.6	-0.7	-1.2	-1.1	-2.7	-1.7
Breastfed as a baby	1.9	2.4	4.5	1.5	1.7	1.1	1.6	0.7	2.1	2.0	1.8	1.4	1.6	0.7	1.7
Peak expiratory flow (PEF)	1.9	4.4	17.8	2.2	1.6	2.6	4.2	1.9	1.7	1.8	1.4	1.4	1.6	2.1	-0.0
Commuting to job workplace: Car/motor vehicle	1.9	2.1	4.0	-1.5	-1.4	-1.0	-0.8	-1.9	-2.0	-1.8	-1.8	-1.6	-1.4	-0.7	-0.6
Family relationship satisfaction	1.8	2.2	4.4	-0.5	2.0	1.8	1.0	-0.4	1.7	1.4	1.8	2.0	2.1	-0.6	-0.8
Leg pain on walking	1.8	2.2	7.3	2.2	1.2	1.2	-0.6	2.7	1.2	1.3	0.7	1.3	1.2	2.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.9	12.5	2.6	1.8	2.1	3.5	0.4	1.7	1.0	2.8	1.9	1.8	0.6	0.1
Average weekly champagne plus white wine intake	1.8	2.5	8.2	2.6	1.6	1.6	-0.7	0.8	1.2	1.5	0.1	1.5	1.6	1.1	2.9
Eye problems/disorders: Glaucoma	1.8	2.2	3.8	1.4	1.7	1.5	0.8	1.1	1.8	1.9	1.9	1.6	1.7	0.7	0.7
Depressed Affect (Nagel 2018)	1.7	3.6	6.0	-2.0	-2.1	-1.4	0.6	-2.1	-2.5	-2.1	-1.5	-2.0	-2.0	-2.3	-1.1
Ulcerative Colitis	1.7	2.4	4.2	1.8	1.5	1.7	1.4	2.1	1.6	1.8	1.8	1.4	1.4	1.1	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	4.0	-1.6	-1.9	-1.7	-0.4	-0.5	-2.0	-1.5	-0.8	-1.9	-1.9	-0.3	-1.1
Eye problems/disorders: Cataract	1.7	1.9	5.2	-1.4	-1.2	-1.9	-1.4	-2.0	-1.2	-0.8	-0.6	-1.1	-1.2	-2.3	-0.4
Smoking Status	1.6	3.9	7.0	-0.3	2.6	2.6	2.2	0.6	2.2	1.9	2.0	2.7	2.6	0.9	-0.3
Ever highly irritable/argumentative for 2 days	1.6	1.9	4.7	1.0	1.1	1.2	2.2	1.6	1.7	2.1	0.5	0.9	1.0	0.2	1.6
Neck or shoulder pain in last month	1.6	2.3	3.9	-1.8	-1.7	-1.6	-0.2	-1.3	-1.5	-1.4	-1.6	-2.0	-1.8	-1.4	-1.0
Lung FEV1/FVC ratio	1.5	7.8	72.8	2.1	0.2	1.0	8.5	1.7	1.3	1.9	2.5	0.1	0.1	-0.7	-0.7
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	6.0	-1.8	-2.0	-2.5	0.4	-1.2	-1.5	-0.6	-0.1	-2.0	-2.1	-1.5	-0.5
Hair/balding pattern: Pattern 3	1.5	2.3	4.1	1.4	1.8	2.0	1.9	1.2	1.7	1.4	0.8	2.0	1.8	0.5	0.3
Health satisfaction	1.5	2.0	6.7	-1.2	-1.4	-2.6	-0.8	-1.4	-0.6	-0.6	-0.9	-1.3	-1.4	-2.0	-1.4
Commuting to job workplace: Public transport	1.5	1.8	3.7	1.6	1.2	0.5	0.8	1.5	1.8	1.4	1.9	1.3	1.1	1.4	0.9
Taking other prescription medications	1.4	2.1	7.0	1.5	1.3	0.5	0.9	1.6	2.2	2.6	1.4	1.5	1.2	0.4	0.2
Alcohol intake versus 10 years previously	1.4	2.1	7.7	-2.4	-1.5	-1.9	0.5	0.0	-0.8	-0.1	-0.5	-1.6	-1.5	-2.8	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	3.3	-0.7	-1.7	-1.3	1.8	-0.3	-1.4	-0.7	-1.1	-1.6	-1.6	-1.4	-0.2
Ever had bowel cancer screening	1.4	1.7	4.0	1.6	1.5	1.3	0.7	2.0	1.6	1.3	0.3	1.4	1.4	0.9	0.0
Risk taking	1.4	2.1	3.6	-0.8	-1.9	-1.8	-0.2	-1.5	-1.6	-1.3	-1.1	-1.9	-1.9	-1.0	-1.3
Body mass index (BMI)	1.3	5.6	11.0	-1.7	-2.7	-2.8	-2.0	-1.8	-3.0	-3.3	-1.9	-2.8	-2.6	-0.7	-1.9
Past tobacco smoking	1.3	2.3	4.2	-1.0	-1.9	-2.1	-0.6	-0.9	-1.6	-1.5	-1.6	-2.0	-1.8	-1.7	-0.6
Blood clot in the leg (DVT)	1.3	1.6	2.5	-1.5	-1.3	-1.5	-1.4	-1.1	-1.3	-1.2	-0.2	-1.0	-1.3	-1.6	-1.3
Smoking status: Previous	1.3	2.0	3.3	0.7	1.7	1.8	0.0	1.5	1.3	1.0	1.7	1.8	1.7	1.7	-0.3
Sensitivity / hurt feelings	1.2	2.1	5.0	-2.1	-1.5	-1.5	0.4	-0.9	-1.3	-1.3	-0.2	-1.6	-1.5	-1.4	-2.2
Arm fat percentage (right)	1.2	4.7	10.4	-1.3	-2.4	-2.5	-2.1	-1.9	-2.8	-3.2	-1.6	-2.5	-2.4	-0.5	-1.0
Arm fat mass (right)	1.2	5.0	9.5	-1.4	-2.6	-2.8	-2.0	-1.9	-2.9	-3.1	-1.6	-2.7	-2.5	-0.5	-1.1
Glaucoma (self-reported)	1.2	1.4	2.2	0.9	1.4	1.3	0.6	0.9	1.2	1.5	1.3	1.4	1.5	0.9	0.7
Arm fat percentage (left)	1.2	4.7	9.4	-1.3	-2.5	-2.7	-1.9	-2.0	-2.7	-3.1	-1.6	-2.6	-2.5	-0.8	-1.0
Mood swings	1.2	2.1	5.8	-1.3	-1.4	-1.3	1.5	-1.6	-1.1	-0.8	0.3	-1.5	-1.4	-2.4	-1.9
Arm fat mass (left)	1.2	5.1	9.4	-1.3	-2.6	-3.0	-1.9	-1.8	-2.9	-3.1	-1.6	-2.8	-2.6	-0.6	-1.2
Alcohol drinker status: Previous	1.2	1.4	2.7	0.9	1.4	1.6	0.6	0.8	0.8	0.3	1.6	1.6	1.4	1.5	0.4
Number of treatments/medications taken	1.1	1.9	5.2	1.2	1.4	0.9	0.8	2.1	1.8	2.3	0.8	1.5	1.4	0.6	-0.1
Hayfever, allergic rhinitis or eczema	1.1	2.4	9.4	2.3	0.4	0.3	1.6	3.1	1.2	1.7	1.2	0.2	0.3	1.2	1.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.3	1.0	1.0	0.7	2.1	1.6	1.5	1.9	0.0	0.9	0.9	0.0	0.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.3	1.4	1.7	0.6	0.3	0.3	1.8	1.2	0.6	1.5	1.6	-0.6	0.0
Ever taken oral contraceptive pill	1.1	1.2	2.8	-1.5	-1.4	-0.5	1.1	-0.7	-1.7	-1.2	-0.2	-1.5	-1.3	-0.0	-0.6
Schizophrenia vs Biploar Disorder	1.0	1.3	2.4	1.2	1.1	1.6	1.3	1.3	1.0	1.2	0.6	1.1	1.1	0.1	1.4
Neuroticism (2016)	1.0	1.4	11.2	1.5	0.2	0.4	3.4	0.1	0.9	0.7	0.7	-0.1	0.1	-0.7	0.8
Hand grip strength (right)	1.0	2.6	6.2	-0.6	-2.5	-1.9	-1.2	-0.2	-2.1	-1.3	-0.8	-2.5	-2.5	-0.1	-1.0
Townsend deprivation index at recruitment	1.0	1.4	3.0	1.6	1.0	0.9	0.7	1.4	1.7	1.7	1.3	0.9	1.0	0.2	1.0
Fed-up feelings	1.0	1.9	4.2	-1.6	-1.4	-1.3	0.5	-1.7	-1.5	-1.1	-0.4	-1.4	-1.4	-2.0	-1.2
Impedance of leg (left)	1.0	4.7	12.0	1.5	2.1	2.2	2.1	1.2	2.7	3.2	0.2	2.3	2.1	0.0	3.5
Illnesses of siblings	1.0	1.4	4.5	-2.1	-1.2	-0.4	0.4	-1.3	-1.6	-1.8	-0.6	-1.0	-1.2	-0.1	-0.9
Falls in the last year	1.0	1.3	3.0	1.1	1.5	1.7	0.8	0.3	1.1	0.5	0.7	1.6	1.6	0.9	0.8
Happiness	1.0	1.2	6.3	-1.9	-0.6	-0.5	-0.1	-2.5	-0.8	-0.7	-0.2	-0.5	-0.6	-1.1	-0.3
Wears glasses or contact lenses	1.0	1.1	2.6	0.7	1.5	1.6	0.7	0.3	0.9	0.3	1.0	1.5	1.5	0.4	1.1
Mother’s age at death	1.0	1.2	2.9	-1.7	-1.2	-1.2	-0.5	-0.7	-1.1	-0.5	0.0	-1.0	-1.2	-1.2	-1.7
Ever depressed for a whole week	1.0	1.2	2.7	0.9	0.8	1.2	1.6	0.9	0.9	1.5	1.6	0.9	0.8	0.5	0.8
Heart disease (siblings)	1.0	1.2	3.2	1.8	0.5	-1.1	-0.3	0.6	1.4	1.8	0.8	0.4	0.5	-1.2	1.1
Body Mass Index (BMI) (2010)	0.9	1.2	2.6	1.6	0.6	1.3	1.5	1.4	0.7	1.4	0.4	0.6	0.6	1.3	0.9
Blood White Count	0.9	6.7	11.9	-2.8	-3.2	-1.5	3.5	-1.1	-3.1	-2.5	-2.3	-3.2	-3.2	-1.4	-1.6
Respiratory disease	0.9	2.0	5.7	1.7	1.5	1.1	-0.4	2.4	1.7	2.0	0.8	1.4	1.4	0.7	0.4
Neuroticism	0.9	2.1	7.0	-1.5	-1.4	-1.2	0.2	-2.0	-1.5	-1.3	-1.0	-1.4	-1.3	-2.6	-0.1
Hearing difficulty/problems: Yes	0.9	1.4	6.5	-1.1	-1.1	-2.0	0.5	-0.3	-0.1	0.2	-0.8	-1.1	-1.1	-2.6	0.3
Relative age of first facial hair	0.9	1.9	3.8	1.4	1.5	1.9	0.1	1.6	1.2	1.0	0.4	1.6	1.5	1.2	1.9
Pain all over the body in last month	0.9	0.9	4.2	-0.8	-1.0	-0.2	0.1	-0.4	-1.0	-0.9	-0.7	-1.0	-1.0	0.9	-2.1
Weight	0.9	4.7	8.4	-1.5	-2.5	-2.7	-1.2	-1.6	-2.9	-2.9	-1.9	-2.7	-2.5	-0.4	-1.4
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	4.5	-0.9	-0.9	-0.2	-1.3	-1.7	-1.7	-2.1	-1.9	-0.8	-0.8	0.4	0.2
Medication: Seretide 50 evohaler	0.9	1.1	2.7	0.1	1.2	1.6	1.1	0.8	0.9	0.5	-0.2	0.9	1.1	1.6	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	2.6	1.6	1.0	0.7	0.2	1.3	1.0	0.6	0.3	1.0	1.0	1.5	1.0
Whole body fat mass	0.9	3.8	6.7	-1.1	-2.3	-2.6	-1.4	-1.6	-2.5	-2.6	-1.9	-2.4	-2.3	-0.6	-0.6
Leg fat mass (right)	0.9	3.6	6.2	-1.2	-2.2	-2.5	-1.1	-1.7	-2.4	-2.3	-1.8	-2.4	-2.2	-0.7	-1.0
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.6	1.3	1.0	0.7	1.3	-0.6	1.3	0.9	0.4	1.0	0.9	0.3	1.9
Loneliness, isolation	0.9	1.3	3.8	-1.3	-1.0	-0.7	1.1	-1.9	-0.9	-0.8	-0.2	-0.9	-1.0	-1.9	-0.2
Irritability	0.9	1.6	4.2	0.8	1.5	1.2	0.8	-0.1	1.5	2.1	1.6	1.5	1.5	0.1	0.5
Impedance of whole body	0.9	4.8	10.5	1.9	2.5	2.1	1.6	0.7	2.9	2.8	1.0	2.6	2.4	0.2	3.2
Ovarian Cancer	0.8	1.1	6.3	1.2	0.3	0.1	2.5	1.0	0.9	1.7	0.5	0.4	0.3	0.1	-0.2
HbA1C	0.8	0.9	2.2	-1.1	-1.2	-1.5	0.8	0.2	-0.5	-0.0	-0.3	-1.3	-1.2	-1.2	-1.0
Lupus	0.8	1.2	6.5	0.4	-0.1	-0.4	-0.7	1.5	0.1	-0.1	-2.3	-0.1	-0.2	0.2	2.6
Allergy or Eczema	0.8	2.2	10.5	2.2	-0.0	-0.1	2.1	3.2	0.8	1.2	0.9	-0.1	-0.1	0.5	1.9
Impedance of leg (right)	0.8	3.8	9.9	1.1	1.9	2.1	1.9	0.8	2.4	3.0	0.2	2.1	1.9	0.1	3.1
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	2.8	-1.6	-0.3	-0.5	-1.7	-0.7	-0.6	-1.2	1.0	-0.5	-0.2	-0.6	-1.3
Had other major operations	0.8	1.0	2.2	-0.9	-1.2	-1.5	0.0	-0.1	-1.0	-0.9	-0.2	-1.1	-1.2	-1.1	-1.2
Impedance of arm (right)	0.8	3.9	7.7	2.0	2.3	2.2	0.7	1.0	2.3	1.9	1.2	2.4	2.3	1.3	2.8
Worrier / anxious feelings	0.8	1.5	3.4	-1.8	-1.3	-0.7	-0.5	-0.9	-1.8	-1.5	-0.7	-1.3	-1.2	-1.3	-0.3
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	25.4	1.2	0.5	1.6	5.0	-0.2	0.2	0.5	1.5	0.5	0.5	0.7	0.2
Gout (self-reported)	0.8	1.1	2.3	0.9	1.1	1.0	0.4	1.3	1.3	1.5	0.7	1.1	1.0	0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.8	1.0	5.2	0.6	0.5	0.5	0.6	2.3	0.7	0.9	0.9	0.6	0.5	0.5	-1.6
Medication: Blood pressure	0.8	1.4	3.7	0.6	0.9	0.5	1.3	1.9	1.5	1.8	1.7	1.0	0.9	-0.2	-0.1
Pulse rate, automated reading	0.8	2.6	5.8	-1.4	-1.4	-1.8	-2.4	-1.2	-1.1	-1.7	-2.4	-1.6	-1.5	-1.5	-0.1
Number of full sisters	0.8	1.0	4.0	-0.3	-0.1	-1.5	-1.3	-1.5	0.2	-0.2	-0.8	-0.2	-0.2	-2.0	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.6	1.0	0.5	0.7	1.5	1.6	0.8	1.2	0.9	0.6	0.6	-0.3	1.0
Smoking status: Current	0.8	1.3	7.0	-0.1	0.5	0.4	2.6	-0.1	1.5	1.9	0.8	0.4	0.4	-0.9	0.2
Number of self-reported non-cancer illnesses	0.8	1.4	6.2	1.7	0.4	0.4	1.1	2.5	0.9	1.3	1.0	0.4	0.4	1.7	0.2
Medication: Lisinopril	0.8	1.1	5.8	-1.2	-0.7	-0.4	0.4	-0.9	-0.9	-0.8	1.3	-0.6	-0.7	-0.0	-2.4
Ever had prostate specific antigen (PSA) test	0.8	1.0	6.8	1.7	0.5	0.5	0.5	-0.1	0.6	-0.1	-0.5	0.4	0.4	0.3	2.6
Leg fat mass (left)	0.8	3.3	5.5	-1.1	-2.2	-2.4	-1.0	-1.6	-2.3	-2.3	-1.7	-2.3	-2.1	-0.6	-1.1
Neuroticism (Nagel 2018)	0.7	1.6	3.2	-1.1	-1.4	-1.0	-0.1	-1.4	-1.8	-1.6	-1.1	-1.4	-1.3	-1.6	-0.6
Alzheimer’s Disease (in mother)	0.7	0.8	2.6	0.6	0.9	0.7	-0.2	0.1	1.1	1.2	0.7	0.8	0.9	0.9	1.6
Prostate Cancer	0.7	1.0	4.2	0.3	0.5	1.1	0.8	1.1	0.2	0.5	-0.3	0.4	0.5	2.0	2.1
Fasting Glucose	0.7	0.9	4.0	-2.0	-0.7	-1.1	0.3	-1.3	-0.7	-0.5	-0.4	-0.7	-0.7	-1.1	-0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.3	0.9	1.1	1.1	0.2	0.8	1.1	1.0	1.0	1.0	1.1	0.3	0.7
Angina	0.7	0.9	2.1	-1.5	-1.0	-0.9	1.2	0.5	-0.9	-0.1	-0.5	-1.1	-0.9	-1.4	0.2
Vitamin and mineral supplements	0.7	0.9	7.1	0.6	-0.4	-1.0	-0.2	-0.8	-0.1	0.2	-0.9	-0.4	-0.4	-0.7	2.7
Current tobacco smoking	0.7	1.2	6.0	-0.2	0.6	0.4	2.4	0.1	1.4	1.8	1.0	0.4	0.5	-0.9	0.1
Trunk fat mass	0.7	3.0	5.8	-0.7	-2.0	-2.3	-1.4	-1.4	-2.2	-2.4	-1.7	-2.1	-2.0	-0.4	-0.3
Qualifications: None of the above	0.7	1.4	5.1	1.4	1.1	1.4	-0.4	2.3	1.4	1.3	0.8	1.1	1.1	0.2	-0.0
Depression (self-reported)	0.7	0.9	1.9	0.3	-1.2	-1.2	0.1	-1.4	-0.7	-0.5	-1.2	-1.2	-1.2	-0.7	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	19.7	1.1	0.3	1.5	4.4	-0.4	0.0	0.0	1.2	0.3	0.4	0.6	0.2
Impedance of arm (left)	0.7	3.3	5.9	1.9	2.1	1.7	0.8	0.7	2.4	2.1	1.3	2.1	2.0	0.7	2.4
Medication: Amlodipine	0.7	0.9	3.1	0.9	1.1	0.8	0.6	0.3	1.2	0.6	1.8	0.9	1.0	-1.0	-0.3
Leg fat percentage (right)	0.7	2.6	4.4	-1.1	-1.8	-1.8	-0.9	-1.7	-1.9	-2.0	-2.1	-1.9	-1.8	-0.9	-0.5
Number of children fathered	0.7	0.8	2.4	-0.7	-0.0	0.3	-1.5	-1.5	-0.9	-1.5	0.1	0.1	-0.0	-0.3	0.9
Heart disease (mother)	0.7	0.9	2.6	0.1	0.2	-0.6	1.1	-1.0	0.7	1.3	1.0	0.3	0.2	-1.6	1.4
Knee pain experienced in last month	0.7	1.0	6.5	0.7	0.2	0.0	-2.6	-0.2	-0.2	-0.6	-1.4	0.2	0.2	1.7	0.4
Long-standing illness, disability or infirmity	0.7	1.1	4.8	0.9	0.3	-0.9	-0.2	2.2	1.4	1.9	1.0	0.3	0.3	-0.4	-0.3
Ever smoked	0.7	1.2	2.6	0.3	1.3	1.6	0.7	0.2	1.1	1.2	1.3	1.4	1.3	1.4	0.5
Fractured/broken bones in last 5 years	0.7	0.9	2.5	0.7	0.9	1.6	0.2	0.6	0.4	0.6	0.7	1.2	1.0	1.5	0.6
Basal cell carcinoma (self-reported)	0.7	0.9	4.2	0.2	0.9	0.6	1.1	-0.2	0.9	-0.0	1.3	0.8	0.9	0.1	-2.0
Major Depression (MDD)	0.6	0.8	2.7	0.6	0.8	0.1	0.9	0.6	1.0	1.0	1.6	1.1	0.8	0.1	-0.9
Breast Cancer	0.6	1.6	5.9	-0.8	-1.4	-1.8	0.1	-0.9	-0.7	-0.2	-0.7	-1.4	-1.4	-2.4	-0.9
Mean Putamen Volume	0.6	0.7	2.6	-0.2	-0.6	-1.1	0.1	-0.9	-0.1	0.1	1.1	-0.8	-0.7	-1.6	-1.0
Blood Eosinophil Count	0.6	4.3	14.5	2.2	1.9	0.6	1.9	1.2	2.8	2.8	3.8	1.8	1.8	-1.1	-0.5
Lung FVC	0.6	3.2	16.6	1.1	1.4	2.1	4.1	-1.4	0.7	0.5	2.6	1.5	1.5	0.1	-0.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.6	0.9	0.3	-0.4	1.3	1.4	1.2	1.6	0.4	0.4	0.3	0.3	-0.7
Ever had hysterectomy (womb removed)	0.6	0.7	3.8	0.1	0.4	0.4	-2.0	1.7	-0.0	-0.6	0.0	0.3	0.4	1.0	-0.1
Medication for hormone replacement therapy	0.6	0.6	1.3	-0.6	-1.0	-0.7	1.1	0.1	-0.5	-0.0	0.9	-0.9	-1.0	-0.6	-1.1
Medication: Levothyroxine sodium	0.6	0.9	8.4	0.0	0.2	-0.0	0.0	2.9	0.7	1.5	0.1	0.3	0.2	0.0	-0.2
High blood pressure (mother)	0.6	0.8	2.5	-1.6	-0.6	0.6	0.1	-1.3	-1.0	-0.7	-1.3	-0.5	-0.5	0.1	1.0
Waist circumference	0.6	2.2	3.9	-1.2	-1.6	-2.0	-1.7	-0.7	-1.6	-2.0	-1.1	-1.8	-1.6	-0.4	-1.2
Mouth/teeth dental problems	0.6	0.9	2.3	-0.8	-1.3	-0.5	-1.1	-0.7	-1.5	-1.2	-0.7	-1.1	-1.2	0.4	0.1
Allergy	0.6	1.5	8.1	-1.8	-0.3	0.0	-0.8	-2.9	-1.0	-1.4	-1.3	-0.3	-0.3	-0.5	-0.9
Mouth/teeth dental problems: Dentures	0.6	0.9	2.3	0.5	1.5	1.0	-0.5	-0.1	1.3	0.6	-0.0	1.3	1.5	-0.8	0.8
Medication: Lansoprazole	0.6	0.6	1.6	0.6	0.4	-0.0	1.3	1.1	0.8	1.0	1.2	0.3	0.4	-0.6	1.0
Illnesses of mother	0.6	0.8	5.3	0.4	-0.4	-1.4	-0.1	-0.7	-0.0	-0.7	0.3	-0.5	-0.5	-0.3	-2.3
Exposure to tobacco smoke at home	0.6	0.7	2.2	0.4	0.9	1.0	1.5	-1.0	0.9	0.1	0.5	0.9	0.9	-0.1	-0.4
Headache pain in last month	0.6	1.1	2.4	-1.6	-0.9	-0.3	1.5	-1.2	-1.1	-0.7	-1.3	-0.8	-0.9	-0.6	-0.8
Body fat percentage	0.6	2.4	4.7	-0.6	-1.7	-2.1	-1.3	-1.6	-1.8	-2.2	-1.6	-1.8	-1.7	-0.7	-0.1
Arm fat-free mass (right)	0.6	2.9	5.2	-1.4	-2.2	-2.3	-0.3	-0.7	-2.3	-1.8	-1.1	-2.3	-2.2	-0.4	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.3	-1.1	-1.0	-0.4	1.8	-0.1	-0.8	-0.2	-0.6	-1.1	-1.0	-0.1	-1.0
Medication: Allopurinol	0.6	0.8	1.9	0.8	1.2	0.4	-0.1	0.8	1.4	1.0	1.2	1.1	1.1	-0.0	-0.1
Arm predicted mass (right)	0.6	2.9	5.5	-1.5	-2.2	-2.3	-0.3	-0.7	-2.2	-1.7	-1.1	-2.3	-2.2	-0.5	-1.5
Medication: Aspirin	0.6	0.8	2.9	0.7	0.5	0.1	0.9	1.0	1.1	1.7	1.4	0.5	0.5	-0.2	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.9	-0.2	-0.9	-0.7	1.4	-1.1	-0.5	-0.1	0.0	-1.0	-1.0	-0.7	0.8
Commuting to job workplace: Walk	0.6	0.6	2.5	-0.1	0.6	0.8	-0.9	1.6	0.2	0.1	0.5	0.7	0.6	1.4	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.8	-0.2	-0.0	-0.7	1.7	-0.4	0.2	-0.0	1.8	-0.1	-0.0	-0.8	-1.9
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.3	0.3	-0.4	0.4	-1.3	1.0	-0.7	-0.7	-1.2	-0.5	-0.5	1.5	0.3
High cholesterol (Self-reported)	0.6	1.1	2.7	0.9	1.0	0.4	0.8	1.5	1.6	1.6	1.4	0.9	0.9	-0.1	0.5
Medication: Bendroflumethiazide	0.6	1.0	2.1	0.1	-1.0	-1.4	-1.3	-0.4	-0.5	-0.4	-1.2	-1.1	-1.1	-1.1	1.0
Basal metabolic rate	0.6	3.1	6.4	-1.3	-2.1	-2.2	-0.7	-0.9	-2.5	-2.2	-1.1	-2.3	-2.1	0.1	-1.8
Leg fat percentage (left)	0.6	2.1	4.0	-0.8	-1.6	-1.7	-0.8	-1.4	-1.7	-1.9	-2.0	-1.7	-1.6	-0.9	-0.4
Number of operations (self-reported)	0.6	0.9	1.8	-0.6	-1.2	-1.4	1.1	1.1	-0.8	0.0	0.1	-1.0	-1.1	-1.2	-0.5
Supplements: Calcium	0.6	0.7	2.3	0.3	0.8	0.5	0.7	0.2	0.8	1.2	1.5	0.9	0.9	-0.1	-0.5
Arm predicted mass (left)	0.6	3.1	5.7	-1.5	-2.1	-2.3	-1.0	-0.9	-2.4	-2.0	-1.2	-2.2	-2.1	-0.4	-1.5
Worry (Nagel 2018)	0.5	1.0	1.8	0.1	-1.0	-0.7	-0.7	-0.2	-1.3	-1.3	-1.4	-1.1	-1.0	-1.0	1.0
Alzheimer’s Disease (in father)	0.5	0.6	2.1	-0.9	-0.8	-1.2	-0.6	0.2	-0.2	0.0	0.0	-0.7	-0.8	-0.4	-1.5
Ulcerative Colitis (UC)	0.5	1.0	4.0	1.0	0.2	0.2	2.0	1.4	0.8	1.3	1.0	-0.0	0.2	-0.8	-0.8
Coronary Artery Disease (CAD)	0.5	0.6	3.5	0.3	0.2	1.0	1.9	1.0	0.3	0.8	0.7	0.3	0.2	0.8	0.2
Schizophrenia (2014)	0.5	1.1	4.4	2.1	0.7	0.9	1.5	0.4	0.9	0.9	0.8	0.8	0.6	1.1	0.9
Hypothyroidism (self reported)	0.5	1.1	4.1	-0.3	0.8	0.4	0.3	2.0	0.9	1.6	1.8	0.9	0.8	0.2	-0.7
Hand grip strength (left)	0.5	1.4	2.8	-0.6	-1.6	-1.5	-1.1	-1.2	-1.4	-1.1	-0.6	-1.7	-1.7	-0.4	-0.7
Pack years adult smoking proportion	0.5	0.8	3.0	-0.3	-0.8	-1.6	-0.2	-0.6	-0.1	0.1	0.0	-1.0	-0.9	-1.7	-0.8
Leg fat-free mass (left)	0.5	2.4	4.8	-1.1	-1.8	-2.0	-0.6	-1.0	-2.2	-2.1	-0.4	-1.9	-1.8	0.2	-1.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.8	0.8	1.0	-0.2	-0.3	-1.0	1.0	0.1	0.2	1.0	1.0	-1.3	0.1
Leg predicted mass (left)	0.5	2.5	4.8	-1.1	-1.8	-2.1	-0.7	-1.1	-2.2	-2.1	-0.5	-2.0	-1.8	0.2	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.5	-1.3	-1.1	-0.9	0.0	-1.3	-1.4	-1.6	-0.1	-1.2	-1.1	-0.6	-0.5
Financial difficulties in last 2 years	0.5	0.7	2.0	-0.9	-1.0	-0.6	1.4	-0.2	-0.6	-0.5	0.7	-1.0	-1.0	-0.6	-0.9
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	3.0	1.7	0.3	0.5	0.2	1.6	0.4	0.7	0.6	0.1	0.3	0.2	0.4
Fluid intelligence score	0.5	1.1	5.6	0.2	-1.1	-1.1	0.4	0.4	-0.4	0.3	-2.4	-1.3	-1.1	0.1	1.2
Neuroticism score	0.5	1.1	4.5	-0.8	-1.1	-1.0	0.7	-1.1	-0.8	-0.7	-0.3	-1.1	-1.1	-2.1	-0.1
Trunk fat-free mass	0.5	2.7	6.0	-1.6	-2.0	-1.8	-0.7	-0.5	-2.4	-1.9	-1.2	-2.1	-2.0	0.3	-1.6
Time employed in main current job	0.5	0.6	3.5	0.3	0.0	0.1	-1.9	1.4	-0.0	-0.1	-0.5	-0.1	0.0	1.0	-0.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	5.9	1.4	-0.0	-0.7	2.4	0.9	0.8	1.3	-0.1	-0.1	-0.1	-0.1	1.1
Medication: Cholesterol lowering	0.5	0.8	1.9	0.1	0.9	1.0	-0.2	0.6	1.0	1.4	1.4	0.9	1.0	0.9	0.6
Trunk predicted mass	0.5	2.8	6.1	-1.6	-2.0	-1.8	-0.7	-0.5	-2.5	-2.0	-1.2	-2.1	-2.0	0.2	-1.6
Hair/balding pattern: Pattern 4	0.5	1.3	3.6	-0.7	-1.4	-1.1	1.1	0.6	-1.0	-0.1	-0.7	-1.2	-1.3	-1.3	-1.9
High blood pressure (siblings)	0.5	0.7	1.4	1.1	1.1	0.6	0.1	0.9	1.1	1.2	-0.0	1.0	1.1	0.2	0.2
Angina (self-reported)	0.5	0.7	1.9	-1.3	-0.8	-0.8	1.2	0.3	-0.6	0.1	-0.5	-0.8	-0.7	-1.4	0.2
Leg fat-free mass (right)	0.5	2.5	4.4	-0.9	-1.8	-2.1	-0.4	-1.0	-2.1	-2.1	-0.4	-2.0	-1.9	0.0	-1.9
Back pain experienced in last month	0.5	0.8	5.3	-0.7	-0.4	-0.3	1.2	-0.6	-0.3	-0.6	-0.0	-0.4	-0.4	-0.7	-2.3
Medication: Aspirin	0.5	0.7	2.7	0.8	0.5	0.0	0.9	0.5	1.1	1.6	1.0	0.6	0.5	-0.6	-0.0
Whole body water mass	0.5	2.9	5.9	-1.4	-2.1	-2.1	-0.6	-0.7	-2.4	-2.0	-0.9	-2.2	-2.1	-0.0	-1.7
Hearing aid user	0.5	0.6	4.1	-0.8	-0.5	-1.1	0.5	-0.2	-0.2	0.2	0.2	-0.7	-0.4	-2.0	0.2
Arm fat-free mass (left)	0.5	2.5	5.0	-1.4	-1.9	-2.0	-0.7	-1.0	-2.2	-2.0	-1.1	-2.0	-1.8	-0.3	-1.4
Diastolic blood pressure, automated reading	0.5	1.6	3.5	-1.0	-1.4	-1.9	-1.0	-0.8	-1.2	-1.2	-1.5	-1.4	-1.5	-0.7	-1.0
Unable to work because of sickness or disability	0.5	0.6	1.5	0.7	0.6	-0.2	0.9	1.2	1.0	1.0	1.0	0.6	0.6	0.4	-0.4
Commuting to job workplace: Cycle	0.5	0.7	1.7	0.0	0.8	0.9	1.3	0.1	1.0	0.5	1.1	0.7	0.8	-1.0	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.3	-0.9	-0.9	-1.0	-0.8	-0.8	-0.8	-0.8	-0.1	-0.5	-0.8	-1.2	-1.0
Pack years of smoking	0.5	0.8	2.6	-0.4	-0.8	-1.5	-0.6	-0.8	-0.1	-0.2	0.1	-0.9	-0.8	-1.6	-1.2
Age at First Birth	0.4	0.6	1.4	0.8	1.0	0.4	0.3	-0.1	1.2	0.7	0.7	1.0	1.0	0.7	-0.9
Triglycerides	0.4	0.6	2.7	0.5	0.9	1.7	1.0	0.3	0.5	0.4	0.2	0.9	0.9	0.5	0.4
BMI	0.4	2.5	5.5	-0.8	-1.6	-2.1	-2.2	-0.9	-1.6	-2.4	-0.8	-1.7	-1.6	0.3	-1.6
Type 2 Diabetes (T2D) (2018)	0.4	0.7	5.5	-0.7	0.6	0.0	-0.2	-0.2	0.3	-0.1	2.3	0.6	0.6	0.7	-0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.8	-0.1	-0.1	-0.5	-1.7	0.7	-0.1	-0.2	0.6	-0.0	-0.0	-0.2	1.1
Diabetes (father)	0.4	0.5	1.1	-0.7	-0.9	-0.7	0.1	0.7	-0.5	0.2	-0.9	-1.1	-0.9	0.2	0.2
Severe depression (siblings)	0.4	0.4	1.2	0.3	0.2	-0.3	1.1	-0.6	0.7	0.6	-0.9	-0.1	0.1	-0.4	1.1
Trunk fat percentage	0.4	1.7	3.8	-0.3	-1.4	-1.8	-1.2	-1.4	-1.6	-2.0	-1.3	-1.4	-1.4	-0.5	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.6	-1.2	-0.9	-0.5	-0.2	-1.6	-1.3	-1.3	-0.0	-0.9	-0.8	-0.5	-0.6
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.2	1.1	0.8	0.8	0.7	0.5	0.5	0.5	0.3	0.8	0.8	-0.4	0.6
Qualifications: CSEs or equivalent	0.4	0.5	1.1	-0.4	0.6	1.0	1.1	0.2	0.5	0.3	1.0	0.6	0.6	0.2	-0.9
Multivitamins +/- minerals	0.4	0.5	2.9	-0.7	-0.2	0.5	-1.0	0.4	-0.6	-0.8	-0.2	-0.1	-0.2	0.4	-1.7
Stomach or abdominal pain in last month	0.4	0.5	1.5	-0.9	0.6	0.3	-0.0	-0.3	0.4	0.0	-1.2	0.5	0.7	-0.8	1.1
Chronic bronchitis/emphysema (father)	0.4	0.5	2.9	-1.0	-0.1	-0.7	-1.7	0.1	-0.1	0.3	0.2	-0.1	-0.1	-0.8	0.6
Number of incorrect matches in round	0.4	0.6	1.6	0.4	0.2	-0.3	1.3	-0.3	0.9	0.9	1.1	0.2	0.2	-1.2	-1.2
Forced vital capacity (FVC)	0.4	1.5	11.9	0.7	0.5	1.2	3.5	-0.8	0.0	0.4	1.2	0.5	0.5	0.4	0.9
Heart attack	0.4	0.5	1.2	-0.6	-1.0	-0.8	-0.1	0.4	-0.6	0.1	-1.1	-1.0	-1.0	-0.2	0.2
Noisy workplace	0.4	0.5	2.1	-0.3	0.7	0.8	1.4	0.5	0.5	0.4	-0.1	0.7	0.7	-0.3	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	4.2	-0.5	-0.1	-0.2	-2.1	-0.8	-0.3	0.2	-0.3	-0.0	0.0	0.2	0.3
Lung cancer (father)	0.4	0.4	2.6	-0.2	0.3	0.1	-0.2	-1.3	0.0	-0.4	-0.1	0.3	0.4	-0.2	1.6
Pulse wave Arterial Stiffness index	0.4	0.4	3.0	0.2	-0.1	-0.7	-1.7	-0.8	-0.0	0.1	-0.1	-0.2	-0.1	-0.7	0.7
Tense / ‘highly strung’	0.4	0.7	2.6	0.0	-1.1	-1.6	-0.4	-0.4	-0.6	-0.3	-0.5	-1.0	-1.1	-1.0	-0.2
Pulse wave reflection index	0.4	0.4	0.9	0.7	0.7	1.0	-0.9	-0.6	0.2	-0.4	0.2	0.6	0.7	0.8	-0.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.1	0.3	-0.1	-0.7	0.4	-0.2	-0.2	0.1	-1.5	-0.2	-0.2	0.8	1.8
Medication: Paracetamol	0.4	0.7	2.0	-0.6	0.0	0.1	1.4	1.1	0.2	0.9	-0.9	-0.1	0.1	-1.3	-1.4
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.7	-0.5	0.2	-0.1	-1.6	1.0	-0.1	-0.8	0.3	0.2	0.2	0.2	-1.1
Forced vital capacity (FVC), Best measure	0.4	1.4	8.3	1.1	0.7	1.6	2.9	-0.4	0.2	0.2	1.2	0.7	0.8	0.6	0.8
Pulse wave peak to peak time	0.4	0.4	3.5	-0.3	0.0	0.6	1.9	0.7	0.0	-0.1	0.0	0.1	-0.0	0.6	-0.5
Eye problems/disorders: None of the above	0.4	0.5	1.4	0.1	-0.6	0.1	1.0	1.0	-0.2	-0.4	-0.8	-0.6	-0.7	1.2	-0.0
Migraine (self-reported)	0.4	0.5	1.1	-1.1	-1.0	-0.7	0.6	-0.8	-0.8	0.0	-0.0	-1.0	-1.0	0.2	-0.7
Medication: Ibuprofen	0.4	0.5	1.5	0.7	0.3	-0.2	0.2	0.8	0.5	0.7	0.6	0.3	0.2	1.2	-1.2
Chest pain or discomfort	0.4	0.6	3.8	0.5	-0.3	-0.4	1.9	0.7	0.2	0.4	-1.4	-0.4	-0.4	0.0	0.4
Supplements: Vitamin C	0.4	0.4	3.2	-0.3	0.6	0.4	0.5	0.1	0.4	0.3	0.1	0.5	0.6	0.3	-1.8
Illnesses of siblings: Diabetes	0.4	0.4	2.9	0.8	0.2	-0.0	-1.7	-0.7	0.3	-0.5	-0.5	0.1	0.1	0.1	-0.6
Whole body fat-free mass	0.4	2.5	5.2	-1.3	-1.9	-2.0	-0.5	-0.6	-2.3	-1.9	-0.9	-2.1	-1.9	0.1	-1.7
Medication for cholesterol	0.4	0.7	2.0	0.1	0.8	1.4	-0.4	0.3	0.0	-0.3	-1.4	1.0	0.9	0.4	1.1
Illnesses of father: None of the above (group 1)	0.4	0.5	1.2	-0.8	-0.4	0.5	-0.1	-0.9	-0.9	-1.1	-1.1	-0.3	-0.3	-0.9	0.3
Leg predicted mass (right)	0.4	2.3	4.1	-0.9	-1.8	-2.0	-0.4	-0.9	-2.0	-2.0	-0.4	-1.9	-1.8	0.1	-1.9
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.0	-0.3	-1.0	-0.9	0.3	0.1	-0.6	0.2	0.3	-1.0	-0.9	-0.6	-0.8
Medication: Paracetamol	0.4	0.6	2.0	-0.2	0.3	0.5	1.4	0.7	0.4	1.2	-0.8	0.4	0.4	-1.1	-1.0
Medication: Atorvastatin	0.4	0.5	2.1	-1.1	-0.1	-0.5	-0.6	-1.5	-0.1	0.1	0.5	-0.0	-0.1	-1.4	-0.3
Average weekly beer plus cider intake	0.4	0.6	2.7	0.1	-0.3	0.1	1.6	0.7	0.6	0.8	0.4	-0.2	-0.3	-0.2	-1.4
Myopia	0.4	0.6	1.8	-0.1	0.8	1.0	0.6	0.3	0.4	0.7	0.4	0.8	0.8	1.4	1.0
Pain experienced in last month	0.4	0.6	3.4	1.3	0.6	0.1	0.4	-0.2	0.6	0.4	-0.2	0.6	0.6	-0.5	1.8
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.9	1.3	0.3	0.2	0.3	0.3	0.7	0.4	-1.7	0.1	0.2	1.1	1.1
Supplements: Zinc	0.3	0.3	0.9	0.2	-0.6	-0.5	0.8	-0.4	-0.2	-0.2	-0.8	-0.7	-0.6	-1.0	-0.0
Medication: Co-codamol	0.3	0.3	1.5	-0.1	0.0	0.3	0.5	-1.2	-0.4	-0.8	-0.2	0.1	0.0	0.7	-0.8
Maternal smoking around birth	0.3	0.5	2.0	0.5	-0.9	-1.4	-0.1	0.3	-0.6	-0.7	-0.2	-0.9	-0.9	-0.2	-0.7
Serious illness, injury or assault to yourself	0.3	0.4	2.0	0.3	0.6	0.7	-1.4	0.3	0.3	0.2	-0.4	0.8	0.7	0.5	0.5
Sitting height	0.3	2.1	7.7	-1.2	-1.2	-1.6	-0.3	-2.8	-1.4	-1.2	-1.7	-1.2	-1.3	-0.8	1.4
Hearing difficulty/problems with background noise	0.3	0.4	1.9	-1.1	-0.2	-0.3	0.6	-0.1	-0.1	0.1	-0.5	-0.3	-0.2	-0.9	1.4
Hair/balding pattern: Pattern 2	0.3	0.4	1.7	0.6	-0.5	-0.5	-0.7	-1.3	-0.1	0.1	-0.3	-0.6	-0.6	-0.1	0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.9	0.6	0.0	0.2	1.4	0.8	0.2	1.0	0.0	0.1	0.0	0.8	0.4
Hip circumference	0.3	1.5	3.2	-0.3	-1.3	-1.6	-1.1	-0.5	-1.6	-1.8	-1.1	-1.4	-1.2	0.4	-1.2
Father’s age at death	0.3	0.4	1.9	-0.1	0.2	0.8	-1.4	1.3	-0.3	-0.6	0.2	0.1	0.2	0.6	-0.3
Pulse rate	0.3	0.5	1.4	0.4	0.6	-0.6	-0.4	0.0	1.2	0.9	0.9	0.6	0.6	-0.9	0.6
Asthma	0.3	0.6	4.0	0.7	0.3	0.1	-0.5	2.0	0.4	0.8	0.6	0.3	0.3	0.5	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.8	0.2	0.2	-0.5	-0.7	0.0	0.2	0.0	0.2	0.1	0.2	1.2	-1.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	3.3	-0.1	0.5	0.0	0.3	1.8	0.7	1.3	0.7	0.6	0.4	-0.1	-0.3
Exposure to tobacco smoke outside home	0.3	0.4	1.8	-0.0	-0.6	-0.7	0.7	-0.3	0.3	0.7	0.5	-0.3	-0.6	-1.4	0.4
Age at first live birth	0.3	0.5	1.9	1.2	0.4	0.6	0.6	0.5	0.5	0.3	0.2	0.6	0.4	1.4	0.4
Qualifications: College or University degree	0.3	0.9	2.6	-0.3	-1.0	-0.7	1.1	-1.6	-1.0	-0.8	-0.9	-1.0	-1.0	0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.2	-0.1	-1.0	-0.7	1.4	-0.6	-0.8	0.1	-1.5	-0.8	-1.0	0.5	-0.2
Diabetes diagnosed by doctor	0.3	0.4	1.6	-1.1	-0.4	-1.3	-0.5	-0.5	-0.3	-0.0	0.9	-0.5	-0.4	-0.5	-0.3
Mineral and other dietary supplements	0.3	0.3	1.6	0.0	-0.5	-0.6	1.3	-0.4	0.1	0.9	-0.0	-0.6	-0.5	-0.1	0.4
Asthma (self-reported)	0.3	0.5	4.3	0.6	-0.0	-0.2	-0.6	2.1	0.1	0.8	0.3	-0.0	-0.0	0.3	0.3
Medication: Gliclazide	0.3	0.3	0.6	0.2	0.7	0.4	-0.2	-0.1	0.6	-0.1	0.6	0.8	0.7	0.7	-0.7
Guilty feelings	0.3	0.4	1.1	-1.1	-0.6	-0.3	0.3	-0.8	-0.6	-0.6	0.0	-0.6	-0.5	-0.9	0.2
Financial situation satisfaction	0.3	0.4	2.1	-0.7	-0.5	0.5	1.4	-0.6	-0.5	-0.2	0.0	-0.3	-0.5	-0.5	-0.4
Medication: Blood pressure	0.3	0.6	2.1	-0.1	-0.8	-1.4	-0.9	-1.0	-0.6	-0.5	0.6	-0.9	-0.9	-0.1	0.0
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.8	0.0	0.6	1.0	-0.0	1.4	0.2	-0.3	0.4	0.7	0.7	0.3	-0.9
Illnesses of father: High blood pressure	0.3	0.3	1.0	1.0	0.4	-0.2	0.5	-0.2	0.4	0.8	0.8	0.3	0.5	1.0	0.0
Age started oral contraceptive pill	0.3	0.4	1.9	-0.4	0.3	-0.0	-1.4	-0.8	-0.1	-0.8	-0.4	0.2	0.3	-0.6	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.7	0.1	0.2	-0.1	1.3	1.3	0.6	0.8	-0.0	0.2	0.2	0.3	0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.9	-0.3	-0.8	-0.7	0.1	0.4	-0.5	0.1	-0.9	-0.9	-0.9	-0.0	0.3
Bipolar Disorder (2018)	0.2	0.2	1.0	0.4	-0.1	-0.3	0.9	-0.1	0.4	0.2	0.5	-0.3	-0.1	1.0	-0.5
Depression (Nagel 2018)	0.2	0.3	2.3	0.6	0.1	0.4	1.5	0.6	0.3	0.7	0.4	0.3	0.1	0.1	0.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	4.7	0.8	0.2	0.2	-0.2	0.2	0.1	0.1	-2.2	0.0	0.1	0.9	1.6
Reaction Time	0.2	0.4	2.0	-0.5	-0.6	-0.5	0.6	0.3	-0.5	-0.4	-0.2	-0.5	-0.6	-1.4	0.1
Primary Biliary Cirrhosis	0.2	0.3	1.1	-0.4	0.2	0.4	0.5	0.2	-0.1	-0.5	0.2	0.3	0.3	1.1	-1.0
Waist Hip Ratio (WHR)	0.2	0.7	2.1	-0.7	0.8	-0.1	-1.3	-0.1	1.3	0.8	1.4	0.7	0.7	-0.4	-0.7
Tanning	0.2	2.2	8.0	-2.8	-1.4	-0.9	0.3	-1.9	-1.4	-1.4	-1.0	-1.3	-1.4	-1.3	-1.3
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.3	-0.4	-0.5	0.1	1.2	-0.6	-0.5	0.0	0.1	-0.5	-0.5	-0.6	-0.1
Medication: Metformin	0.2	0.3	1.7	-0.5	0.1	-0.6	0.3	-0.0	0.4	0.8	0.2	0.0	0.1	-0.2	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	2.3	-0.6	0.1	0.4	1.5	-0.1	0.2	0.2	0.6	0.1	0.0	0.5	-0.7
High blood pressure	0.2	0.4	0.9	-0.3	-0.9	-0.8	0.1	0.4	-1.0	-0.8	0.4	-0.7	-0.9	0.7	-0.2
Medication: Atenolol	0.2	0.3	1.3	-0.6	0.2	0.4	-0.7	0.8	-0.0	0.1	1.1	0.2	0.1	-0.1	-0.6
Nervous feelings	0.2	0.4	0.9	0.5	-0.6	-0.2	0.3	-0.9	-0.6	-1.0	-1.0	-0.6	-0.5	-0.8	0.7
Had menopause	0.2	0.2	1.0	-0.6	-0.4	-0.6	-0.1	0.1	-0.3	-0.5	0.1	-0.2	-0.3	-1.0	-0.2
Diabetes (self-reported)	0.2	0.3	1.1	-0.3	0.4	-0.6	-0.5	-0.3	0.5	0.5	1.0	0.3	0.4	-0.6	0.1
Medication: Ramipril	0.2	0.3	1.0	0.3	-0.1	-1.0	-0.7	1.0	0.3	0.4	0.7	-0.1	-0.1	-0.2	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.1	0.9	0.3	0.2	0.8	1.1	0.5	0.9	-0.3	0.1	0.2	0.6	0.1
Wheeze or whistling in the chest in last year	0.2	0.4	1.6	-0.6	-0.6	-0.8	-1.3	0.3	-0.4	-0.6	-0.5	-0.7	-0.6	-0.1	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.3	0.1	0.4	0.0	-1.1	0.1	-0.1	0.1	0.2	0.3	0.5	0.4	1.1
Shortness of breath walking on level ground	0.2	0.3	1.3	0.8	0.0	-0.3	-0.7	1.1	0.3	0.7	-0.3	0.1	-0.0	0.5	0.2
Emphysema/chronic bronchitis	0.2	0.2	1.4	0.4	-0.1	0.4	1.2	0.4	0.1	0.2	0.2	-0.1	-0.1	-0.6	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	1.3	0.2	-0.1	0.2	-0.9	-1.0	-0.5	-1.1	0.2	-0.2	-0.1	-0.3	0.8
Medication: Omeprazole	0.2	0.3	1.7	0.0	0.4	0.2	1.3	0.8	0.3	0.2	-0.1	0.4	0.3	0.6	0.4
Comparative height size at age 10	0.2	1.3	3.6	-1.0	-1.5	-1.0	1.9	0.4	-1.4	-0.6	0.0	-1.6	-1.5	0.0	-0.3
Overall health rating	0.2	0.3	0.7	-0.2	-0.8	-0.7	-0.1	0.8	-0.5	-0.1	-0.2	-0.8	-0.8	0.7	-0.0
Age at last live birth	0.2	0.3	1.2	0.1	-0.2	-0.0	0.6	0.3	0.0	0.1	-1.1	-0.3	-0.2	1.0	0.2
Average weekly red wine intake	0.2	0.3	2.1	1.5	-0.2	-0.2	0.5	0.2	0.1	0.2	0.7	-0.2	-0.1	0.6	0.4
Friendships satisfaction	0.2	0.3	0.8	-0.5	0.3	-0.3	-0.4	-0.4	0.4	0.2	0.8	0.4	0.3	-0.9	-0.8
Qualifications: nursing, teaching	0.2	0.3	1.2	-0.8	-0.1	-0.3	-0.2	-1.0	-0.1	0.4	-1.1	-0.2	-0.1	-0.1	0.3
Cholesterol lowering medication	0.2	0.3	1.4	0.2	0.4	0.2	1.2	0.9	0.7	0.6	0.6	0.3	0.4	-0.1	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.3	1.5	0.6	0.1	0.2	1.2	-0.6	0.3	0.2	0.6	0.0	0.0	1.0	-0.1
Schizophrenia (2018)	0.1	0.2	0.7	0.4	0.2	0.5	0.8	-0.8	0.1	0.1	0.3	0.3	0.2	0.4	0.4
Alzheimer’s Disease (including proxy)	0.1	0.2	0.7	-0.4	-0.1	-0.5	-0.9	-0.5	0.3	0.4	0.4	-0.1	-0.1	0.2	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.6	0.2	-0.2	0.1	0.8	-0.5	-0.1	-0.1	0.1	-0.3	-0.2	0.6	-0.3
Blood Red Count	0.1	1.0	3.0	1.3	1.0	0.9	0.8	0.8	1.1	0.6	0.4	0.8	0.9	0.6	1.7
Heel T-Score	0.1	1.2	2.6	-1.0	-1.6	-1.3	0.6	0.7	-0.8	-0.2	-1.2	-1.6	-1.6	-0.5	-0.4
Systolic Blood Pressure	0.1	0.6	2.7	0.2	0.4	0.2	1.0	0.5	0.9	1.6	0.0	0.4	0.3	0.1	1.3
Cardiovascular Disease	0.1	0.4	1.2	-0.5	-0.5	-1.0	0.6	-0.4	-0.0	-0.2	0.9	-0.5	-0.6	0.3	-1.1
Chronotype (morning person)	0.1	0.2	1.0	-0.1	0.1	1.0	0.5	0.5	0.0	0.4	0.1	0.3	0.2	-0.2	0.6
Alcohol usually taken with meals	0.1	0.2	1.2	1.1	-0.4	-0.2	-0.3	-0.2	-0.2	-0.3	0.1	-0.4	-0.4	0.3	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.8	-0.6	-0.3	0.0	0.9	-0.1	-0.1	0.2	0.5	-0.2	-0.3	0.1	-0.7
Birth weight	0.1	0.2	0.9	-0.5	-0.3	-0.7	-0.9	-0.1	-0.3	-0.0	-0.5	-0.2	-0.3	-0.3	0.1
Number of full brothers	0.1	0.2	0.6	0.4	0.2	-0.7	-0.5	0.1	0.6	0.5	0.7	0.2	0.1	-0.4	-0.1
Worry too long after embarrassment	0.1	0.2	0.7	0.4	0.5	0.4	0.2	-0.2	0.4	0.6	0.7	0.4	0.5	-0.2	0.8
Mean time to correctly identify matches	0.1	0.3	1.4	-0.4	-0.5	-0.6	-0.2	0.6	-0.2	-0.3	-0.0	-0.4	-0.5	-1.2	0.1
Alcohol intake frequency.	0.1	0.3	1.0	-1.0	-0.3	0.4	0.5	-0.6	-0.7	-0.7	0.5	-0.2	-0.2	-0.2	-0.6
Suffer from ‘nerves’	0.1	0.1	0.4	0.5	-0.2	-0.5	0.5	0.2	0.0	-0.1	-0.2	-0.4	-0.2	-0.6	-0.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.5	0.4	0.4	0.4	0.4	0.7	0.2	-0.0	0.0	0.3	0.4	0.1	0.1
Hypertension (Self-reported)	0.1	0.3	0.7	0.0	-0.8	-0.7	0.2	0.5	-0.7	-0.5	0.4	-0.7	-0.8	0.7	0.1
Osteoarthritis (self-reported)	0.1	0.2	0.7	0.3	-0.3	-0.0	0.1	-0.5	-0.4	-0.8	-0.5	-0.5	-0.4	0.3	0.1
Miserableness	0.1	0.3	1.1	-0.2	-0.4	-0.0	1.1	-0.7	-0.5	-0.4	-0.0	-0.5	-0.4	-0.6	-0.1
Vascular/heart problems diagnosed by doctor	0.1	0.4	0.7	0.3	0.7	0.8	0.1	-0.7	0.8	0.6	-0.3	0.7	0.7	-0.6	-0.1
Blood Platelet Count	0.0	0.2	0.7	-0.5	0.4	0.8	0.0	0.4	0.4	0.6	0.4	0.3	0.4	-0.2	0.2
Height	0.0	0.5	2.8	0.2	0.5	0.4	0.7	0.4	0.0	0.2	-0.8	0.5	0.5	0.6	1.7
Hair Pigment	0.0	0.8	3.5	0.8	0.4	0.8	1.0	1.9	0.4	1.1	-0.2	0.7	0.5	0.6	1.0
Systolic blood pressure, automated reading	0.0	0.1	0.4	0.0	0.3	-0.1	0.2	-0.0	0.3	0.1	-0.6	0.2	0.2	-0.3	0.6
Standing height	0.0	0.3	0.9	-0.3	-0.3	-0.6	0.9	-0.2	-0.5	0.1	-0.5	-0.4	-0.4	0.3	0.9

Hub : Genes

ANXA6

Models

Trait associations