[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:147,012,186-149,420,698

Best TWAS P=8.59e-98 · Best GWAS P=1.7e-147 conditioned to 2.33e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FBXO38	0.05	0.01	blup	489	0.02	1.5e-03	15.8	-16.8	2.3e-63	-0.71	0.02	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HTR4	0.06	0.03	lasso	4	0.03	4.3e-05	23.8	18.3	1.8e-74	0.78	0.01	0.98	FALSE
3	GTEx	Cells Transformed fibroblasts	FBXO38	0.18	0.05	enet	35	0.10	1.1e-07	15.8	-14.1	1.9e-45	-0.60	0.64	0.33	TRUE
4	GTEx	Cells Transformed fibroblasts	AFAP1L1	0.17	0.10	enet	16	0.15	4.7e-11	-4.5	-5.2	1.5e-07	0.02	1.00	0.00	FALSE
5	METSIM	Adipose	SH3TC2	0.08	0.06	bslmm	546	0.07	2.8e-10	2.1	5.6	2.2e-08	0.02	1.00	0.00	TRUE
6	ROSMAP	Brain Pre-frontal Cortex	SPINK9	0.08	0.07	enet	21	0.07	1.4e-09	13.8	13.3	1.9e-40	0.48	1.00	0.00	TRUE
7	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FBXO38	0.04	0.04	blup	52	0.04	4.8e-03	14.5	-19.6	2.3e-85	-0.74	0.05	0.13	TRUE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	FBXO38	0.05	0.02	lasso	2	0.02	4.3e-02	13.7	-20.5	4.3e-93	-0.76	0.04	0.28	TRUE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FBXO38	0.02	0.03	enet	2	0.03	1.9e-04	-19.6	-21.0	8.6e-98	-0.75	0.03	0.65	TRUE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FBXO38	0.03	0.01	enet	6	0.01	5.0e-02	16.2	-16.4	1.6e-60	-0.53	0.08	0.04	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPINK5	0.10	0.06	blup	106	0.10	6.4e-11	-4.7	-5.8	4.9e-09	-0.16	0.02	0.97	TRUE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AFAP1L1	0.27	0.12	lasso	6	0.14	2.1e-08	-5.5	-5.2	1.7e-07	0.05	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	FBXO38	0.11	0.02	blup	52	0.04	8.2e-06	16.2	-14.5	9.6e-48	-0.53	0.69	0.07	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	FBXO38	0.03	0.02	blup	51	0.02	7.7e-04	13.8	-15.3	3.8e-53	-0.63	0.55	0.08	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	AFAP1L1	0.07	0.05	enet	8	0.06	6.3e-07	-5.1	-5.6	2.1e-08	0.03	0.02	0.98	TRUE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	FBXO38	0.05	0.01	blup	51	0.02	7.9e-03	-7.5	-16.4	3.9e-60	-0.66	0.05	0.17	TRUE
17	The Cancer Genome Atlas	Rectum Adenocarcinoma	FBXO38	0.13	0.17	enet	16	0.15	2.3e-04	16.0	-16.7	8.7e-63	-0.65	0.12	0.30	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	FBXO38	0.06	0.01	enet	7	0.01	3.2e-02	-8.3	-15.1	2.1e-51	-0.58	0.04	0.26	TRUE