Hub : Genes

BLVRB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.038 0.0180 0.018 0.003 0.010 0.009 0.010 0.005 1.1e-01 1.9e-02 2.5e-02 1.8e-02 6.3e-02
2 YFS Blood 0.485 0.0404 0.000 0.334 0.366 0.403 0.271 0.373 7.5e-114 3.5e-127 1.4e-143 6.6e-89 2.6e-130

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.8 1.2 1.9 0.7 1.4
Bipolar Disorder or Schizophrenia 0.3 0.7 0.7 0.8 0.8
Depressed Affect (Nagel 2018) 0.0 0.0 0.0 -0.1 0.2
Depression (Nagel 2018) 0.1 0.1 0.1 -0.3 0.3
Intelligence (Savage-Jansen 2018) 0.1 0.4 0.6 -0.5 0.8
Neuroticism (Nagel 2018) 0.2 0.5 1.0 0.0 1.0
Schizophrenia (2018) 0.0 0.1 0.2 0.4 -0.2
Schizophrenia vs Biploar Disorder 2.2 2.9 3.8 1.9 -1.4
Worry (Nagel 2018) 1.0 2.2 3.7 -0.9 1.9
Alzheimer’s Disease (in mother) 0.4 0.4 0.9 0.9 -0.0
Alzheimer’s Disease (in father) 0.2 0.3 0.5 -0.1 0.7
Alzheimer’s Disease (including proxy) 0.3 0.5 0.7 -0.4 0.9
Crohns Disease (2017) 0.9 2.0 2.9 1.7 -1.1
Irritable Bowel Disease (IBD) 2.0 4.8 5.0 2.2 -2.2
Ulcerative Colitis (UC) 1.3 2.4 3.8 1.0 -1.9
Major Depression (MDD) 0.1 0.1 0.2 0.3 -0.5
Reaction Time 0.6 1.2 2.3 1.5 -0.1
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.3 -0.5 -0.2
Breast Cancer 0.1 0.2 0.2 -0.4 -0.5
Ovarian Cancer 0.2 0.2 0.4 -0.6 0.2
Prostate Cancer 0.2 0.3 0.5 -0.7 -0.2
Age at First Birth 0.0 0.0 0.1 0.0 -0.2
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.2 0.4 0.6 -0.2
Coronary Artery Disease (CAD) 3.5 4.2 4.6 2.1 -1.9
Crohns Disease (2012) 1.0 1.6 1.6 1.3 -1.2
Mean Putamen Volume 0.2 0.2 0.4 0.7 0.1
Fasting Glucose 0.8 0.9 1.0 1.0 -0.9
HbA1C 1.8 1.9 3.0 1.0 -1.7
HDL Cholesterol 0.0 0.1 0.1 0.4 0.1
LDL Cholesterol 0.0 0.1 0.1 -0.1 -0.3
Lupus 0.5 0.8 1.0 -0.7 1.0
Neuroticism (2016) 0.1 0.2 0.3 -0.6 0.1
Primary Biliary Cirrhosis 0.3 0.4 0.5 -0.6 -0.7
Rheumatoid Arthritis 0.1 0.1 0.2 -0.4 0.0
Schizophrenia (2014) 0.0 0.0 0.1 0.0 0.2
Triglycerides 1.0 1.6 3.0 -1.7 0.5
Type 2 Diabetes (T2D) (2012) 2.0 2.3 3.7 1.0 -1.9
Ulcerative Colitis 0.7 1.0 1.2 1.1 -0.9
Blood Eosinophil Count 1.7 13.0 15.0 -3.9 3.3
Blood Platelet Count 0.2 2.6 4.2 2.1 -1.0
Blood Red Count 0.7 7.2 11.8 -3.4 1.6
Blood White Count 1.0 7.1 12.6 -1.3 3.5
Heel T-Score 0.3 2.5 4.9 2.2 -0.3
BMI 0.2 1.2 1.6 0.9 -1.3
Height 0.6 11.0 17.0 -4.1 2.2
Waist Hip Ratio (WHR) 0.7 3.3 4.8 -2.2 1.4
Systolic Blood Pressure 0.5 2.4 4.5 -0.7 2.1
Smoking Status 2.4 5.8 6.4 2.5 -2.3
Allergy or Eczema 0.9 2.4 3.2 -1.8 1.3
Cardiovascular Disease 0.2 0.8 1.5 0.2 1.2
Hypothyroidism (self reported) 0.9 2.1 3.3 -1.8 1.0
Respiratory disease 0.0 0.1 0.2 -0.1 -0.4
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.0 0.4 -1.0
Lung FEV1/FVC ratio 4.4 22.2 29.1 5.4 -3.9
Lung FVC 3.3 16.8 26.7 -5.2 2.6
Neuroticism 0.5 1.2 2.3 -0.3 1.5
Chronotype (morning person) 0.1 0.1 0.3 -0.0 0.5
Hair Pigment 0.0 0.1 0.1 -0.3 -0.3
Tanning 0.0 0.4 0.7 0.0 -0.9
Hand grip strength (left) 0.0 0.1 0.1 -0.3 0.3
Number of treatments/medications taken 0.5 0.8 1.2 -1.1 -0.7
Average weekly spirits intake 0.1 0.1 0.2 -0.4 -0.0
Sensitivity / hurt feelings 0.1 0.1 0.2 0.5 -0.0
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.3 -0.5 -0.6
Hearing difficulty/problems: Yes 1.6 2.5 3.0 1.4 -1.7
Relative age of first facial hair 1.1 2.3 3.3 1.2 -1.8
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.1 -0.3 -0.1
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.0 -1.0 0.3
Ever had hysterectomy (womb removed) 0.1 0.1 0.1 -0.2 -0.4
Systolic blood pressure, automated reading 0.1 0.4 0.5 0.7 0.6
Eye problems/disorders: Diabetes related eye disease 2.5 2.7 3.4 1.4 -1.8
Angina 0.2 0.3 0.4 0.6 0.3
Medication for hormone replacement therapy 0.6 0.7 0.8 0.9 -0.8
Vitamin and mineral supplements 0.5 0.6 1.3 0.0 -1.1
Supplements: Zinc 1.8 1.9 2.8 1.7 -1.0
Medication: Co-codamol 0.5 0.6 0.8 -0.9 -0.6
Medication: Metformin 0.3 0.4 0.8 0.3 -0.9
Diabetes (father) 0.2 0.2 0.3 0.6 0.3
Diabetes (mother) 0.7 0.8 1.6 -0.2 -1.3
Severe depression (siblings) 0.2 0.2 0.4 0.1 -0.6
Pack years adult smoking proportion 0.3 0.5 0.7 0.8 -0.5
Impedance of leg (right) 0.5 2.3 3.4 1.8 1.1
Leg fat-free mass (left) 0.2 1.1 2.3 -1.5 -0.2
Trunk fat percentage 0.6 2.3 4.0 0.8 -2.0
Hand grip strength (right) 0.3 0.9 1.4 -1.2 0.7
Townsend deprivation index at recruitment 0.5 0.7 1.1 -0.6 1.1
Current tobacco smoking 0.5 0.9 1.1 -0.8 1.0
Average weekly fortified wine intake 0.7 0.9 1.1 -0.8 -1.1
Maternal smoking around birth 0.9 1.3 1.5 1.2 -1.0
Fed-up feelings 0.1 0.2 0.4 0.3 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.5 -0.1 -0.7
Relative age voice broke 1.8 2.7 3.7 1.3 -1.9
Taking other prescription medications 1.0 1.6 2.6 -1.6 0.8
Age when periods started (menarche) 0.7 1.6 3.1 1.8 -0.3
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 0.9 -1.0 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 1.6 1.2 -1.1
Tinnitus: Yes, but not now, but have in the past 1.8 1.9 2.9 -1.0 1.7
Qualifications: CSEs or equivalent 0.3 0.5 0.5 -0.7 0.7
Serious illness, injury or assault to yourself 0.1 0.1 0.2 0.2 -0.5
High blood pressure 0.3 0.7 1.4 -0.0 1.2
Hayfever, allergic rhinitis or eczema 0.9 1.9 2.1 -1.5 1.3
Multivitamins +/- minerals 0.1 0.1 0.3 0.5 0.1
Stomach or abdominal pain in last month 0.9 1.1 2.1 1.4 0.4
Supplements: Glucosamine 1.3 1.6 2.0 -1.4 1.1
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.3 0.4 -0.6
Medication: Atenolol 1.5 1.8 2.0 -1.4 1.3
Medication: Levothyroxine sodium 0.1 0.2 0.5 -0.1 -0.7
Sitting height 0.1 0.6 1.0 -0.4 -1.0
Chronic bronchitis/emphysema (father) 0.3 0.3 0.4 0.6 -0.5
High blood pressure (mother) 0.0 0.1 0.1 -0.0 0.3
Body mass index (BMI) 0.4 1.8 2.6 1.0 -1.6
Impedance of leg (left) 0.2 1.2 2.0 1.4 0.6
Leg predicted mass (left) 0.2 1.1 2.2 -1.5 -0.3
Trunk fat mass 0.3 1.4 2.6 0.3 -1.6
Waist circumference 0.2 0.8 1.5 -1.2 0.2
Number of incorrect matches in round 0.9 1.5 1.8 -1.1 1.3
Past tobacco smoking 2.8 5.2 6.2 -2.0 2.5
Alcohol usually taken with meals 1.4 2.2 4.4 -0.1 2.1
Nervous feelings 0.7 1.4 1.7 -1.0 1.3
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.5 0.1 -0.7
Hearing difficulty/problems with background noise 0.1 0.2 0.4 0.3 -0.6
Hair/balding pattern: Pattern 2 0.5 0.6 1.1 -1.1 0.3
Had menopause 1.4 1.7 2.7 1.6 -0.8
Had other major operations 1.7 2.0 4.0 -2.0 -0.3
Forced vital capacity (FVC) 2.3 9.0 13.2 -3.6 2.2
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 0.7 0.8 -0.8
Ever unenthusiastic/disinterested for a whole week 1.2 1.5 2.2 1.5 -0.8
Qualifications: None of the above 0.5 1.1 1.4 1.2 -0.9
Financial difficulties in last 2 years 0.1 0.2 0.3 -0.2 -0.6
Mouth/teeth dental problems 0.8 1.2 1.5 -1.2 0.9
Heart attack 0.9 1.1 2.0 1.4 -0.5
Allergy 0.6 1.3 2.2 1.5 -0.7
Pain all over the body in last month 0.3 0.3 0.5 -0.2 -0.7
Diabetes (self-reported) 1.1 1.7 2.6 0.9 -1.6
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.2 0.5 -0.5
Medication: Ramipril 4.4 5.7 9.8 -1.2 3.1
Medication: Simvastatin 0.3 0.4 0.9 -0.9 0.0
Fluid intelligence score 0.1 0.2 0.2 -0.5 0.3
Illnesses of siblings 0.8 1.2 2.3 0.2 -1.5
Neuroticism score 0.1 0.1 0.2 0.4 0.3
Weight 0.1 0.5 0.9 -0.3 -0.9
Impedance of arm (right) 0.0 0.0 0.0 -0.1 0.1
Arm fat percentage (right) 0.5 2.0 3.3 0.8 -1.8
Trunk fat-free mass 0.1 0.8 1.3 -1.1 0.5
Hip circumference 0.1 0.3 0.4 -0.6 -0.5
Time employed in main current job 0.2 0.2 0.3 0.3 -0.6
Alcohol intake versus 10 years previously 1.3 1.9 3.1 -1.8 0.8
Father’s age at death 1.2 1.6 2.7 -1.6 0.7
Worrier / anxious feelings 0.0 0.0 0.0 0.0 0.0
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.7 -0.8 -0.1
Falls in the last year 1.9 2.6 3.3 -1.4 1.8
Hair/balding pattern: Pattern 3 4.1 6.1 9.3 3.0 -1.7
Number of live births 0.2 0.3 0.6 -0.8 0.1
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 2.1 -1.4 0.5
Pulse rate 0.8 1.3 2.4 0.4 1.5
Happiness 0.2 0.2 0.3 0.4 -0.6
Noisy workplace 0.7 0.9 1.4 0.6 -1.2
Qualifications: A levels/AS levels or equivalent 0.6 1.4 1.8 -1.3 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 0.5 -0.7 0.4
Mouth/teeth dental problems: Dentures 0.7 1.2 2.1 1.4 -0.6
Asthma 0.1 0.3 0.5 -0.1 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 0.6 -0.6 -0.8
Medication: Cholesterol lowering 0.2 0.2 0.4 -0.6 0.2
Depression (self-reported) 0.1 0.1 0.2 -0.4 0.2
Medication: Lansoprazole 2.9 3.3 4.8 -1.3 2.2
Prospective memory result 0.6 0.7 1.0 1.0 -0.6
Lung cancer (father) 0.3 0.4 0.4 0.7 0.6
Illnesses of mother 0.5 0.6 0.9 -0.6 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.8 3.2 -1.8 0.7
Pulse wave Arterial Stiffness index 1.6 1.9 2.3 -1.5 1.2
Impedance of arm (left) 0.1 0.6 1.0 -1.0 0.3
Arm fat mass (right) 0.4 1.6 2.9 0.5 -1.7
Trunk predicted mass 0.1 0.7 1.2 -1.1 0.5
Standing height 0.4 4.4 6.6 -2.6 1.5
Length of working week for main job 0.5 0.5 1.0 -1.0 0.3
Exposure to tobacco smoke at home 0.0 0.0 0.0 0.1 -0.2
Breastfed as a baby 0.9 1.1 2.3 0.0 1.5
Tense / ‘highly strung’ 0.5 0.8 0.9 0.9 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.5 -0.4 0.7
Hair/balding pattern: Pattern 4 0.0 0.0 0.0 -0.0 -0.2
Birth weight of first child 1.1 2.0 2.1 1.4 -1.4
Peak expiratory flow (PEF) 1.1 2.5 2.6 1.6 -1.6
Pulse wave reflection index 1.0 1.2 2.1 -1.4 0.6
Ever highly irritable/argumentative for 2 days 1.0 1.2 2.3 -1.5 0.4
Loud music exposure frequency 3.8 4.1 6.4 -2.5 1.4
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 0.9 -0.9 0.7
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 1.0 1.0 -1.0
Blood clot in the leg (DVT) 0.9 1.2 2.3 -1.5 -0.3
Medication: Paracetamol 0.1 0.1 0.3 -0.1 -0.5
Headache pain in last month 0.6 1.0 1.7 -1.3 0.4
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 0.9 1.0 -0.9
Glaucoma (self-reported) 0.2 0.2 0.2 0.5 -0.4
Gout (self-reported) 1.6 2.1 2.8 1.2 -1.7
Hypothyroidism/myxoedema (self-reported) 0.5 1.1 1.8 -1.4 0.5
Medication: Amlodipine 0.0 0.0 0.0 0.2 0.1
Medication: Ventolin 100micrograms inhaler 0.0 0.0 0.0 0.2 -0.1
Birth weight 0.6 1.3 1.6 1.3 -1.0
Chronic bronchitis/emphysema (mother) 0.0 0.0 0.0 0.2 -0.0
High blood pressure (siblings) 1.5 2.1 3.7 -0.7 1.9
Forced vital capacity (FVC), Best measure 2.6 9.4 14.0 -3.7 2.2
Body fat percentage 0.4 1.8 2.7 0.9 -1.6
Leg fat percentage (right) 0.4 1.6 2.7 1.6 -0.7
Arm fat-free mass (right) 0.1 0.6 1.1 -1.1 0.1
Exposure to tobacco smoke outside home 0.3 0.4 0.5 0.7 0.5
Comparative body size at age 10 0.2 0.4 0.7 0.8 0.4
Number of full brothers 0.0 0.0 0.1 0.2 -0.1
Worry too long after embarrassment 0.1 0.1 0.2 0.2 0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 2.3 -1.1 1.5
Wheeze or whistling in the chest in last year 0.2 0.3 0.6 0.7 -0.1
Number of children fathered 5.1 5.8 7.8 1.9 -2.8
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 0.6 0.6 -0.7
Age at first live birth 0.2 0.3 0.3 -0.5 -0.5
Pulse wave peak to peak time 1.0 1.2 1.5 1.2 -0.9
Health satisfaction 1.5 1.9 3.1 0.9 -1.7
Shortness of breath walking on level ground 0.3 0.4 0.7 -0.2 0.8
Qualifications: College or University degree 1.1 3.3 4.5 -1.5 2.1
Eye problems/disorders: None of the above 0.2 0.2 0.2 -0.4 0.4
Mouth/teeth dental problems: Loose teeth 2.5 2.9 3.8 1.4 -1.9
Emphysema/chronic bronchitis 0.6 0.7 0.8 0.9 -0.7
Medication for pain relief, constipation, heartburn 0.3 0.6 1.2 -0.1 1.1
Neck or shoulder pain in last month 0.1 0.2 0.3 -0.2 0.6
Medication: Blood pressure 0.5 0.9 1.4 -0.7 1.2
Angina (self-reported) 0.1 0.2 0.2 0.4 0.4
Migraine (self-reported) 0.5 0.6 1.3 -1.1 -0.2
Medication: Ibuprofen 0.6 0.8 1.4 -0.4 -1.2
Medication: Allopurinol 1.6 2.1 3.2 1.0 -1.8
Medication: Omeprazole 1.0 1.2 1.8 -1.4 -0.7
Medication: Seretide 50 evohaler 0.1 0.1 0.2 0.2 -0.4
Mean time to correctly identify matches 0.6 1.2 2.3 1.5 -0.1
Heart disease (mother) 0.0 0.0 0.0 -0.1 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 4.3 5.1 5.1 2.3 -2.2
Whole body fat mass 0.3 1.1 1.8 0.5 -1.4
Leg fat mass (right) 0.3 1.0 1.2 1.1 -0.9
Arm predicted mass (right) 0.1 0.4 0.7 -0.8 0.2
Pulse rate, automated reading 2.7 8.7 16.1 -1.1 4.0
Alcohol intake frequency. 0.5 1.3 2.0 -1.4 0.8
Comparative height size at age 10 1.6 8.9 12.4 -3.5 2.3
Number of full sisters 0.2 0.3 0.5 0.7 0.2
Suffer from ‘nerves’ 1.9 2.9 3.8 -1.4 2.0
Overall health rating 0.1 0.3 0.4 -0.6 -0.4
Chest pain or discomfort 0.7 1.0 1.1 1.0 -0.9
Had major operations 0.5 0.6 1.1 -1.0 0.2
Age at last live birth 0.9 1.3 2.3 -1.5 0.6
Family relationship satisfaction 1.8 2.2 2.3 -1.5 1.5
Leg pain on walking 0.7 0.9 1.8 -1.3 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.4 0.7 -0.5
Commuting to job workplace: Car/motor vehicle 2.7 3.1 3.4 1.7 -1.8
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 1.3 -1.1 0.9
Medication: Aspirin 0.2 0.2 0.3 0.5 0.5
Supplements: Vitamin C 0.3 0.4 0.7 -0.2 0.8
Knee pain experienced in last month 1.2 1.9 3.1 -1.8 0.8
Hypertension (Self-reported) 0.5 1.3 2.6 -0.2 1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 1.6 -1.3 0.7
Illnesses of father: Heart disease 1.5 2.1 2.5 1.3 -1.6
Illnesses of siblings: Diabetes 0.6 0.8 1.4 1.2 -0.4
Smoking status: Previous 5.1 7.6 8.6 2.9 -2.6
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 4.0 -2.0 -0.0
Whole body fat-free mass 0.2 1.0 2.0 -1.4 0.3
Leg fat-free mass (right) 0.4 2.1 4.1 -2.0 -0.2
Arm fat percentage (left) 0.5 1.8 3.5 0.4 -1.9
Average weekly red wine intake 0.2 0.3 0.5 -0.7 0.2
Handedness (chirality/laterality): Left-handed 0.0 0.0 0.1 -0.2 -0.1
Mood swings 0.1 0.1 0.2 0.3 -0.5
Loneliness, isolation 0.0 0.0 0.1 -0.2 -0.0
Long-standing illness, disability or infirmity 0.4 0.7 0.9 -0.6 -1.0
Ever had bowel cancer screening 0.4 0.5 0.9 -0.1 1.0
Diabetes diagnosed by doctor 1.6 2.6 3.7 1.2 -1.9
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.2 1.3 1.1 -1.1
Friendships satisfaction 0.8 0.9 1.0 -1.0 0.9
Qualifications: nursing, teaching 0.3 0.5 0.6 -0.8 0.6
Commuting to job workplace: Walk 0.8 0.9 1.8 1.3 -0.1
Eye problems/disorders: Cataract 1.2 1.4 2.5 -0.6 1.6
Mouth/teeth dental problems: Mouth ulcers 0.0 0.1 0.1 0.3 0.3
Medication for cholesterol 0.3 0.4 0.5 0.7 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.5 0.6 -0.8 0.7
Back pain experienced in last month 1.6 2.3 3.6 -1.9 1.0
Mineral and other dietary supplements 2.1 2.8 3.8 1.3 -2.0
Breast cancer (self-reported) 1.5 1.8 3.5 0.3 -1.9
Asthma (self-reported) 0.2 0.3 0.6 0.1 -0.8
Osteoporosis (self-reported) 0.5 0.6 0.7 -0.9 0.7
Osteoarthritis (self-reported) 0.0 0.0 0.1 0.3 -0.0
Medication: Aspirin 0.1 0.1 0.1 0.4 0.2
Medication: Gliclazide 3.0 3.4 6.0 -2.5 0.9
Illnesses of father: None of the above (group 1) 0.1 0.1 0.2 -0.2 0.4
Smoking status: Current 0.4 0.7 0.8 -0.9 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 1.4 -1.2 0.7
Whole body water mass 0.1 0.8 1.5 -1.2 0.2
Leg predicted mass (right) 0.4 2.0 4.1 -2.0 -0.1
Arm fat mass (left) 0.3 1.2 2.2 0.3 -1.5
Number of self-reported non-cancer illnesses 0.3 0.5 0.7 -0.8 0.5
Average weekly champagne plus white wine intake 0.8 1.1 2.2 -0.0 1.5
Miserableness 0.0 0.1 0.1 0.2 -0.4
Guilty feelings 0.5 0.8 1.5 1.2 0.3
Wears glasses or contact lenses 0.4 0.5 0.8 0.4 -0.9
Ever taken oral contraceptive pill 1.8 2.0 2.5 1.2 -1.6
Hearing aid user 1.6 1.8 2.6 1.6 -1.0
Mother’s age at death 0.5 0.6 0.7 0.8 0.8
Financial situation satisfaction 0.2 0.3 0.4 -0.4 -0.6
Tinnitus: Yes, now most or all of the time 1.2 1.4 2.4 0.5 -1.6
Commuting to job workplace: Public transport 3.2 3.8 5.2 -1.6 2.3
Eye problems/disorders: Glaucoma 0.1 0.1 0.2 0.4 -0.0
Medication: Blood pressure 1.1 2.1 3.1 -1.1 1.7
Pain type(s) experienced in last month: Hip pain 0.4 0.5 0.9 -1.0 0.1
Supplements: Fish oil (including cod liver oil) 1.7 2.2 2.7 -1.3 1.6
High cholesterol (Self-reported) 0.0 0.1 0.1 0.2 -0.3
Medication: Bendroflumethiazide 0.1 0.1 0.2 -0.5 0.2
Medication: Paracetamol 0.4 0.6 1.1 0.3 -1.1
Medication: Lisinopril 0.1 0.1 0.1 -0.3 0.3
Medication: Atorvastatin 0.0 0.0 0.0 -0.2 -0.0
Illnesses of father: High blood pressure 0.5 0.6 1.1 0.3 1.1
Alcohol drinker status: Never 0.5 0.6 1.1 -0.4 1.0
Ever smoked 0.7 1.2 1.7 0.8 -1.3
Basal metabolic rate 0.1 0.6 1.3 -1.1 -0.1
Leg fat percentage (left) 0.3 1.2 1.6 1.3 -0.9
Arm fat-free mass (left) 0.1 0.4 0.7 -0.8 0.3
Number of operations (self-reported) 0.7 1.0 1.9 -1.4 0.1
Average weekly beer plus cider intake 1.4 2.0 2.3 1.5 -1.3
Irritability 0.7 1.2 2.3 1.5 -0.3
Risk taking 0.2 0.2 0.3 0.4 -0.5
Ever had prostate specific antigen (PSA) test 0.1 0.2 0.3 0.0 0.6
Fractured/broken bones in last 5 years 1.1 1.4 2.2 -1.5 0.8
Age started oral contraceptive pill 0.3 0.3 0.5 -0.4 0.7
Diastolic blood pressure, automated reading 0.5 1.6 2.4 0.9 1.5
Ever depressed for a whole week 2.8 3.4 3.9 2.0 -1.7
Unable to work because of sickness or disability 0.2 0.3 0.4 0.7 -0.4
Commuting to job workplace: Cycle 1.0 1.2 2.4 0.2 -1.6
Myopia 0.7 1.1 2.1 -1.4 0.3
Vascular/heart problems diagnosed by doctor 0.3 0.8 1.7 0.0 -1.3
Cholesterol lowering medication 0.2 0.3 0.6 0.8 -0.2
Medication: Omeprazole (e.g. Zanprol) 1.2 1.4 2.0 -1.4 -0.9
Pain experienced in last month 0.5 0.8 1.2 1.1 -0.6
Supplements: Calcium 0.1 0.1 0.2 -0.2 -0.4
Basal cell carcinoma (self-reported) 0.8 0.9 1.7 0.5 -1.3
Heart attack/myocardial infarction (self-reported) 0.8 1.1 1.9 1.4 -0.6
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 3.1 -1.8 0.1
Heart disease (siblings) 0.6 0.7 1.1 0.5 1.1
Alcohol drinker status: Previous 0.3 0.3 0.6 -0.7 -0.3
Pack years of smoking 0.3 0.4 0.6 0.8 -0.4
Impedance of whole body 0.0 0.1 0.2 0.2 0.4
Leg fat mass (left) 0.2 0.8 1.0 0.8 -1.0
Arm predicted mass (left) 0.0 0.2 0.4 -0.6 0.2