TWAS hub - SHKBP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.2540	0.1020	8.1e-03	0.017	NA	0.052	NA	0.057	9.7e-02	NA	1.2e-02	NA	9.1e-03
2	GTEx	Lung	0.1210	0.0365	1.0e-04	0.115	NA	0.091	NA	0.066	4.4e-09	NA	1.8e-07	NA	9.5e-06
3	GTEx	Spleen	0.2340	0.0950	6.7e-03	0.021	NA	0.018	NA	0.002	9.2e-02	NA	1.1e-01	NA	2.8e-01
4	GTEx	Whole Blood	0.1190	0.0360	5.4e-05	0.093	NA	0.036	NA	0.072	6.9e-09	NA	2.5e-04	NA	3.7e-07
5	NTR	Blood	0.0464	0.0117	2.0e-08	0.035	0.033	0.041	0.037	0.038	1.4e-11	4.8e-11	3.1e-13	6.2e-12	2.7e-12
6	ROSMAP	Brain Pre-frontal Cortex	0.0769	0.0317	4.0e-03	0.018	0.019	0.039	0.017	0.021	2.0e-03	1.5e-03	8.2e-06	2.4e-03	7.7e-04
7	YFS	Blood	0.5064	0.0402	0.0e+00	0.092	0.255	0.270	0.261	0.222	1.3e-28	8.1e-83	1.6e-88	4.0e-85	4.2e-71
8	TCGA	Colon Adenocarcinoma	0.0770	0.0400	8.0e-03	-0.004	0.024	-0.004	NA	-0.003	6.1e-01	1.5e-02	7.1e-01	NA	5.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Lung FVC	8.3	42.1	96.3	-0.5	8.9	2.8	9.8	9.5	-2.4	6.7	3.5
Forced vital capacity (FVC), Best measure	6.9	25.3	53.9	-1.7	6.8	2.5	7.3	7.1	-3.4	5.1	2.2
Lung FEV1/FVC ratio	6.8	34.7	63.7	5.4	-7.1	-0.0	-6.7	-8.0	4.7	-6.5	-5.2
Blood clot in the leg (DVT)	5.6	7.2	12.1	-1.2	3.3	1.3	2.7	3.5	-3.0	2.5	3.0
Forced vital capacity (FVC)	5.5	21.0	45.0	-1.6	6.0	2.3	6.7	6.4	-3.4	4.6	2.4
Deep venous thrombosis (DVT) (self-reported)	5.1	6.5	11.6	-1.4	3.1	1.3	2.5	3.4	-2.8	2.1	3.0
Mouth/teeth dental problems: Dentures	3.4	5.7	11.2	1.6	-2.7	-1.9	-3.3	-3.3	2.1	-1.9	-1.6
Eye problems/disorders: None of the above	3.1	3.6	9.5	-0.4	2.6	2.1	2.1	3.1	-0.7	1.6	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.0	9.4	20.2	0.1	4.2	2.4	4.5	4.2	-2.4	2.5	1.4
Alzheimer’s Disease (including proxy)	2.4	3.5	8.9	0.6	2.3	2.7	2.4	3.0	0.5	0.7	0.3
Past tobacco smoking	2.4	4.4	14.4	-1.9	2.1	0.6	2.4	2.4	-0.8	-0.4	3.8
Ever depressed for a whole week	2.4	3.0	6.2	1.2	-1.8	0.4	-1.4	-2.0	1.1	-2.5	-2.4
Sensitivity / hurt feelings	2.3	3.9	9.4	1.0	-2.3	-0.9	-1.6	-2.9	1.3	-3.1	-1.5
Forced expiratory volume in 1-second (FEV1)	2.2	7.3	15.8	-0.0	3.5	2.5	4.0	3.6	-2.2	2.1	1.4
Smoking status: Previous	2.2	3.3	12.6	1.9	-1.4	-0.0	-1.7	-1.8	1.0	1.1	-3.5
Blood Red Count	2.1	20.0	54.2	-3.4	4.2	3.4	4.8	5.2	-7.4	2.2	3.1
Commuting to job workplace: Walk	2.1	2.2	5.4	0.7	1.5	1.2	0.9	1.2	-1.0	2.3	2.3
Smoking Status	2.0	4.7	8.9	2.0	-1.8	-0.4	-2.8	-2.9	2.2	-0.1	-3.0
Relative age voice broke	1.9	2.9	4.8	2.2	-2.0	0.0	-1.9	-1.6	1.9	-1.4	-1.6
Loneliness, isolation	1.9	2.7	7.1	-0.7	-1.6	-2.7	-2.0	-1.7	-1.0	-1.6	1.0
Pack years adult smoking proportion	1.8	2.7	11.4	-0.5	-2.0	-1.0	-3.4	-1.6	-1.2	-0.8	0.2
Allergy	1.8	4.1	8.8	0.4	-2.6	0.4	-2.2	-3.0	2.2	-2.1	-1.7
Medication: Paracetamol	1.8	2.8	6.2	-0.5	-1.3	-2.2	-2.5	-1.9	-1.2	-1.9	1.0
Lupus	1.7	2.6	6.2	-0.5	-2.5	-1.2	-1.6	-2.3	0.6	-2.0	-0.5
Health satisfaction	1.7	2.2	7.5	-0.2	-1.1	-1.2	-1.1	-1.3	1.6	-1.1	-2.7
Townsend deprivation index at recruitment	1.6	2.3	5.8	0.1	2.2	-0.4	1.3	2.4	-1.1	1.7	1.4
Illnesses of mother	1.6	2.0	3.7	1.9	1.5	-0.9	0.6	1.0	-1.9	1.2	1.7
Medication: Paracetamol	1.6	2.7	7.8	-0.6	-1.1	-2.8	-2.1	-2.0	-0.2	-1.9	-0.0
High blood pressure (siblings)	1.6	2.3	4.9	-0.1	1.8	0.4	2.2	2.1	-0.5	2.2	0.7
Back pain experienced in last month	1.6	2.3	5.3	-0.7	1.6	0.1	1.8	2.3	-1.0	2.1	1.2
Ever taken oral contraceptive pill	1.6	1.8	4.4	1.0	-1.5	1.2	-1.8	-2.1	-0.8	-1.0	-0.9
Ever smoked	1.6	2.8	8.8	1.7	-1.5	-0.5	-2.2	-1.9	0.1	0.1	-3.0
Schizophrenia vs Biploar Disorder	1.5	2.0	10.2	3.2	0.3	2.3	0.2	0.1	-0.3	0.6	-0.1
Irritable Bowel Disease (IBD)	1.5	3.7	19.2	4.4	-0.2	1.2	-0.5	-1.1	2.5	-0.1	-1.0
Medication: Co-codamol	1.5	1.7	4.0	-0.7	-1.3	-1.8	-1.5	-2.0	-0.4	-1.0	-0.9
Supplements: Glucosamine	1.5	2.0	4.3	-1.4	-2.1	-1.0	-1.3	-1.7	-0.9	-1.6	-0.6
Number of full brothers	1.5	1.8	6.2	-0.1	-2.5	0.1	-2.1	-1.1	1.1	-1.4	0.1
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.4	1.6	-1.0	1.8	-0.4	-1.0	1.4	-0.5	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	6.6	-2.6	0.3	-0.1	0.4	0.7	-2.0	-0.6	1.4
Illnesses of siblings: Diabetes	1.5	1.8	4.2	1.6	1.1	1.6	0.7	1.5	-0.8	2.1	0.6
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	7.8	2.8	1.4	0.1	1.8	0.8	-0.1	1.9	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	9.3	1.1	1.9	2.3	3.0	2.3	1.0	0.6	0.5
Pain experienced in last month	1.5	2.6	8.4	2.1	-0.6	2.9	0.0	-0.6	2.2	-1.0	-1.3
Pack years of smoking	1.5	2.2	10.5	-0.4	-1.8	-0.8	-3.2	-1.4	-1.1	-0.6	0.2
Maternal smoking around birth	1.4	2.0	9.0	1.7	-0.4	-0.1	-0.4	-1.4	3.0	-0.8	-1.1
Comparative height size at age 10	1.4	7.8	16.6	-2.2	2.9	0.9	4.0	4.1	-1.5	3.7	0.0
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.9	5.2	-2.0	1.4	1.8	2.3	2.0	-1.2	1.8	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	6.6	0.0	0.7	-1.7	0.2	-0.0	-2.6	0.4	1.4
Ever had prostate specific antigen (PSA) test	1.4	1.7	6.6	1.0	-0.4	0.1	0.6	-0.5	2.2	-0.4	-2.6
Commuting to job workplace: Cycle	1.4	1.7	6.2	-0.6	1.7	-0.3	0.8	0.7	-2.5	0.5	1.7
Bipolar Disorder (2018)	1.3	2.0	7.9	-0.2	-1.1	-0.7	-1.3	-1.4	2.8	-0.2	-1.6
Crohns Disease (2017)	1.3	2.8	16.7	4.1	-0.0	1.0	-0.6	-0.6	2.0	0.2	-0.2
Happiness	1.3	1.6	4.1	-0.5	-1.8	-0.5	-0.8	-2.0	0.2	-1.1	-1.7
Impedance of arm (left)	1.3	5.9	20.1	0.4	3.3	1.3	4.5	3.1	-0.6	2.0	-0.2
Loud music exposure frequency	1.3	1.5	3.6	-1.2	-1.5	-1.9	-0.5	-1.3	0.6	-1.5	-0.4
Diastolic blood pressure, automated reading	1.3	3.9	12.8	-0.1	1.8	0.9	2.0	0.8	-3.6	-1.0	3.0
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	3.3	1.4	-1.4	0.2	-1.4	-1.8	0.5	-0.7	-1.5
Illnesses of siblings	1.2	1.7	5.3	-0.5	-1.2	-0.9	-1.5	-1.9	-0.2	-2.3	0.0
Time employed in main current job	1.2	1.4	4.0	-1.3	1.4	-0.2	1.3	1.4	0.1	2.0	-0.1
Hair/balding pattern: Pattern 3	1.2	1.8	3.5	0.8	-1.6	-0.2	-1.8	-1.7	1.9	-0.1	-1.2
Neck or shoulder pain in last month	1.2	1.7	4.7	0.7	-1.8	-1.3	-2.2	-1.7	0.1	0.1	-0.1
Medication: Omeprazole	1.2	1.4	4.5	-2.1	0.2	-1.3	0.2	0.1	-2.0	0.1	1.0
Chest pain or discomfort	1.2	1.8	5.8	0.1	-0.3	-2.4	-0.9	0.1	2.3	1.1	-0.8
Alzheimer’s Disease (in father)	1.1	1.2	4.2	0.8	0.7	1.8	0.5	0.8	2.0	-0.3	-0.4
Body Mass Index (BMI) (2010)	1.1	1.4	4.8	-0.7	-1.6	-1.0	-2.2	-0.9	1.4	-0.3	0.0
Mean Putamen Volume	1.1	1.2	2.8	0.8	0.5	1.4	1.2	0.0	1.3	1.0	-1.7
Rheumatoid Arthritis	1.1	1.5	5.6	-0.0	-0.5	0.7	-0.6	-1.1	2.0	-0.7	-2.4
Supplements: Zinc	1.1	1.2	5.0	1.3	0.2	-1.5	-0.4	-0.3	0.6	2.2	0.3
Age when periods started (menarche)	1.1	2.6	7.1	0.8	-1.7	0.4	-2.2	-2.0	1.0	0.4	-2.7
Stomach or abdominal pain in last month	1.1	1.4	3.8	0.5	1.2	1.1	1.8	1.1	-0.2	1.9	0.4
Pain all over the body in last month	1.1	1.2	4.8	0.4	-0.3	-2.0	-0.3	-0.2	0.4	-2.2	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.8	4.1	-0.4	-1.2	-1.5	-1.5	-2.0	-0.6	-1.9	-0.3
Comparative body size at age 10	1.1	3.0	7.1	1.5	1.7	1.6	1.5	1.8	-1.6	2.7	1.2
Number of children fathered	1.1	1.3	3.7	1.9	-0.7	1.0	-0.9	-0.2	1.8	0.4	-0.9
Alcohol intake frequency.	1.1	2.6	4.1	1.6	2.0	-1.7	1.5	1.6	-0.2	1.7	2.0
Eye problems/disorders: Cataract	1.1	1.3	2.7	0.0	-1.4	-1.4	-1.6	-1.6	0.4	-1.0	-0.1
Average weekly beer plus cider intake	1.1	1.5	5.1	0.4	-1.2	0.7	-1.8	-2.2	0.3	-1.3	-0.2
Myopia	1.1	1.6	4.9	-1.4	-0.4	-1.2	-1.1	-1.0	-2.2	-0.9	1.3
Crohns Disease (2012)	1.0	1.6	9.0	3.0	1.2	0.9	0.3	0.2	-0.3	1.3	0.2
Medication: Levothyroxine sodium	1.0	1.8	4.1	-0.4	-1.6	-1.1	-1.6	-2.0	0.1	-1.3	-1.4
Neuroticism score	1.0	2.1	6.1	0.1	-1.5	-1.7	-1.2	-2.1	0.4	-2.5	-0.1
Impedance of arm (right)	1.0	4.7	15.4	1.0	3.1	1.3	3.9	2.5	0.2	1.7	-1.0
Breastfed as a baby	1.0	1.2	4.1	-1.1	-0.7	1.6	0.5	1.1	0.3	2.0	-0.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.5	-0.6	1.0	0.1	1.9	1.3	-1.2	1.4	1.6
Had major operations	1.0	1.2	2.9	-1.5	1.1	-0.4	1.0	0.5	0.6	1.7	-1.3
Commuting to job workplace: Public transport	1.0	1.1	4.5	-0.9	0.2	-1.0	-0.0	-0.2	-2.1	-0.5	1.6
Medication: Blood pressure	1.0	2.0	4.9	-0.9	-1.5	-2.2	-1.7	-1.3	0.6	-1.7	0.0
Alzheimer’s Disease (in mother)	0.9	1.1	4.2	0.7	0.9	2.0	0.9	1.1	0.7	-0.1	-0.8
Ulcerative Colitis (UC)	0.9	1.6	8.9	3.0	0.3	1.1	0.3	-0.4	1.3	0.0	-1.0
Major Depression (MDD)	0.9	1.1	3.5	0.7	-1.2	0.3	-0.7	-1.3	-0.2	-1.9	-1.3
Prostate Cancer	0.9	1.2	4.9	-0.4	0.4	0.2	0.7	0.6	1.2	1.5	-2.2
Ulcerative Colitis	0.9	1.4	6.3	2.5	0.1	1.2	0.1	-0.3	1.5	-0.2	-1.0
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	6.4	-0.2	-0.2	-2.5	0.1	-0.8	-0.2	0.7	-1.3
Systolic blood pressure, automated reading	0.9	2.5	6.7	0.4	0.9	2.6	2.3	1.8	-0.4	1.1	1.6
Severe depression (siblings)	0.9	1.0	2.4	-0.5	-1.6	-0.2	-0.9	-1.1	1.3	-0.7	-1.1
Medication: Lansoprazole	0.9	1.0	2.3	0.0	1.0	1.4	1.3	1.5	1.1	0.3	-0.1
Length of working week for main job	0.9	1.0	2.9	-1.7	1.0	0.8	0.8	1.0	-0.5	1.3	-0.4
Ever highly irritable/argumentative for 2 days	0.9	1.0	2.4	0.3	0.6	-0.6	0.3	1.0	-1.3	1.5	1.5
Birth weight	0.9	1.9	4.5	0.5	2.1	0.5	2.0	1.7	-0.8	1.6	-0.2
Exposure to tobacco smoke outside home	0.9	1.2	4.5	-0.2	-0.3	-0.5	-0.5	-0.2	-2.1	-0.2	2.0
Shortness of breath walking on level ground	0.9	1.0	4.8	-1.2	-0.7	2.2	-0.2	0.8	0.0	0.6	-0.5
Overall health rating	0.9	1.9	7.3	0.4	-1.1	-2.7	-1.2	-1.5	0.7	-1.3	-0.9
Asthma (self-reported)	0.9	1.7	4.4	-0.4	1.4	-0.2	1.3	2.1	-1.7	1.2	1.1
Medication: Gliclazide	0.9	1.0	3.0	-1.7	1.0	-0.4	1.3	0.5	-0.7	1.0	0.4
Guilty feelings	0.9	1.4	2.8	-0.8	-1.5	-1.3	-1.7	-1.5	0.1	-1.0	0.6
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.2	-1.3	-0.3	-1.7	-0.3	-0.2	-1.8	0.1	0.5
Alcohol drinker status: Previous	0.9	1.0	6.2	-0.4	-1.0	-2.5	-0.2	-0.6	0.8	-0.2	-0.1
Coronary Artery Disease (CAD)	0.8	0.9	6.7	2.6	0.2	0.3	-0.0	-0.3	-0.5	0.0	0.0
Systolic Blood Pressure	0.8	3.9	9.4	-0.7	1.7	1.8	3.1	2.5	-0.8	1.6	2.3
Allergy or Eczema	0.8	2.1	6.6	0.2	1.9	0.7	2.6	1.8	-1.1	1.2	0.4
Frequency of depressed mood in last 2 weeks	0.8	1.1	5.0	0.2	1.1	-0.3	0.9	1.2	-0.6	0.1	2.2
Relative age of first facial hair	0.8	1.7	7.3	0.0	-1.3	-0.3	-1.2	-0.7	2.7	-0.1	-1.6
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	2.3	1.5	-0.8	-1.1	-1.0	-0.8	-0.0	-0.9	-0.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	4.3	-1.0	-0.4	2.1	0.2	0.3	0.2	-1.0	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	7.3	0.0	0.7	-0.9	0.0	0.7	-0.8	0.7	2.7
Asthma	0.8	1.6	4.1	-0.3	1.4	-0.5	1.4	2.0	-1.5	1.2	1.0
Standing height	0.8	8.3	17.1	-3.2	2.9	0.8	4.1	3.7	-1.4	3.1	-2.1
Migraine (self-reported)	0.8	1.0	6.1	-0.1	-0.6	-2.5	-0.8	-0.6	0.7	-0.4	0.0
Heart disease (mother)	0.8	1.0	6.2	-0.5	-0.7	0.3	-0.3	-0.5	2.5	-0.6	-0.5
Leg pain on walking	0.8	1.0	4.5	0.5	-0.8	0.1	-0.6	-0.3	1.3	-0.2	-2.1
Mother’s age at death	0.8	1.0	3.8	-1.9	-0.6	-1.2	-0.4	-0.7	-1.2	0.2	-0.5
Medication: Bendroflumethiazide	0.8	1.2	3.3	0.4	1.5	0.1	1.8	0.9	-0.6	1.7	0.0
Alcohol drinker status: Never	0.8	1.0	2.9	-0.2	1.2	-1.7	1.0	0.5	0.1	0.6	1.3
Number of operations (self-reported)	0.8	1.1	2.7	-1.4	1.6	-0.6	1.3	1.1	-0.7	0.6	0.7
Age started oral contraceptive pill	0.8	1.0	2.9	-1.7	-0.0	-1.4	-0.7	-0.6	-1.1	0.8	0.0
Bipolar Disorder or Schizophrenia	0.7	1.7	5.2	0.3	-1.1	-1.0	-1.8	-1.5	2.3	0.1	-0.9
Neuroticism (2016)	0.7	1.1	2.9	0.2	-1.7	-0.5	-1.1	-1.4	-0.2	-1.3	0.5
Primary Biliary Cirrhosis	0.7	0.9	4.9	0.1	-1.0	0.8	0.2	-0.8	0.4	0.3	-2.2
Height	0.7	13.4	29.5	-4.4	3.2	-0.2	5.4	4.7	-0.7	3.8	-3.4
Respiratory disease	0.7	1.7	3.4	-0.6	1.4	-1.0	1.0	1.8	-1.4	1.7	0.9
Vitamin and mineral supplements	0.7	0.9	2.7	0.9	-0.5	0.1	0.3	0.0	1.0	-1.6	-1.6
Diabetes (father)	0.7	0.9	2.4	-0.5	-1.1	-0.6	-1.3	-1.5	0.6	0.6	0.3
Hayfever, allergic rhinitis or eczema	0.7	1.5	3.0	-0.6	1.5	0.1	1.7	1.6	-1.4	1.2	0.6
Multivitamins +/- minerals	0.7	0.9	3.2	-0.7	0.6	-0.2	0.1	0.5	-1.4	1.8	0.9
High blood pressure (mother)	0.7	1.0	3.2	-1.8	-0.8	-0.3	-0.9	-0.7	-0.9	-0.8	1.3
Had other major operations	0.7	0.8	3.2	-0.6	1.1	-0.7	1.8	0.6	-0.6	0.1	-0.7
Depression (self-reported)	0.7	0.8	2.6	-0.2	0.9	0.1	0.4	1.0	-1.2	-0.8	1.6
Pulse wave Arterial Stiffness index	0.7	0.8	2.9	-1.7	-0.4	-0.5	-0.3	0.1	0.5	1.0	-1.3
Birth weight of first child	0.7	1.3	3.1	1.2	-0.8	-0.3	-1.2	-1.8	1.4	-0.9	-1.0
Pulse wave peak to peak time	0.7	0.8	2.6	1.6	0.6	0.4	0.4	0.2	-0.7	-0.9	1.2
Medication for pain relief, constipation, heartburn	0.7	1.1	2.9	0.6	0.6	1.7	1.4	1.2	-0.5	1.4	0.2
Medication: Allopurinol	0.7	1.0	3.2	1.1	-0.7	1.8	0.1	-1.0	0.8	-0.8	-0.6
Mean time to correctly identify matches	0.7	1.3	5.8	0.4	-0.9	0.9	-0.9	-0.9	2.4	-0.7	-0.9
Pulse rate, automated reading	0.7	2.2	9.4	-3.1	0.3	0.1	0.9	0.2	-2.4	0.1	1.3
Number of full sisters	0.7	0.8	2.9	-0.3	0.6	0.7	0.3	1.1	1.3	1.7	0.2
Family relationship satisfaction	0.7	0.8	3.3	-1.2	-1.1	-0.7	-0.0	-0.2	1.8	-0.4	-0.3
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	3.2	-1.8	0.1	0.3	0.3	0.4	1.2	1.3	-0.7
Illnesses of father: Heart disease	0.7	0.9	4.2	2.1	-0.7	-0.8	-0.3	-0.8	0.5	0.0	-1.1
Leg fat-free mass (right)	0.7	3.5	8.2	-2.9	1.6	0.2	2.4	2.2	-1.7	2.0	0.0
Average weekly red wine intake	0.7	1.1	3.1	-1.8	0.2	-1.3	0.7	1.3	-0.3	0.9	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.5	0.3	-0.4	-0.3	-0.6	-0.3	1.2	-0.7	-1.9
Leg predicted mass (right)	0.7	3.6	8.3	-2.9	1.6	0.2	2.4	2.2	-1.7	2.1	0.0
Financial situation satisfaction	0.7	0.9	1.5	-0.3	-1.0	-1.1	-0.8	-1.0	0.2	-1.2	-1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.6	1.6	0.9	0.4	0.3	-0.0	-0.4	-0.0	-1.6
Fractured/broken bones in last 5 years	0.7	0.9	1.8	-1.1	-0.8	-1.0	-0.6	-1.4	-0.8	-1.1	0.1
Heart attack/myocardial infarction (self-reported)	0.7	0.8	4.6	2.1	-0.5	0.1	-0.7	-0.7	0.8	-0.0	-0.6
Reaction Time	0.6	1.1	4.5	-0.2	-0.7	1.4	-0.8	-0.7	2.1	-0.0	-0.6
HDL Cholesterol	0.6	1.0	3.2	-1.8	-0.5	-0.6	-0.2	-0.7	-1.4	-1.2	0.0
Medication for hormone replacement therapy	0.6	0.7	2.3	0.9	-0.8	0.2	-0.3	-0.4	1.5	-0.4	-1.1
Leg fat-free mass (left)	0.6	2.9	6.7	-2.6	1.4	0.5	2.2	2.1	-1.3	1.8	-0.5
Taking other prescription medications	0.6	0.9	5.0	-1.4	0.5	-2.2	0.0	-0.1	-0.3	0.1	-0.0
Medication: Atenolol	0.6	0.8	1.3	-1.1	-0.9	-0.8	-0.7	-0.7	0.7	-1.1	-0.9
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	0.7	-0.2	-1.5	-1.1	-1.2	-0.5	0.2	-0.5
Leg predicted mass (left)	0.6	3.1	6.8	-2.6	1.5	0.5	2.3	2.2	-1.4	1.8	-0.3
Number of incorrect matches in round	0.6	0.9	2.3	-1.2	0.5	0.4	0.7	1.5	0.4	1.5	0.5
Mouth/teeth dental problems	0.6	0.9	4.1	-2.0	0.2	-1.0	0.6	0.7	-0.7	-0.7	0.8
Heart attack	0.6	0.8	4.1	2.0	-0.5	0.0	-0.7	-0.7	0.8	-0.0	-0.5
Headache pain in last month	0.6	1.1	3.6	-1.9	0.5	-1.3	0.3	0.0	-1.6	0.5	0.6
Hypothyroidism/myxoedema (self-reported)	0.6	1.3	2.3	-1.0	-0.9	-1.0	-1.1	-1.5	-0.3	-1.1	-1.5
Worry too long after embarrassment	0.6	1.0	3.9	-1.3	-1.1	-0.4	-0.5	-1.0	0.3	-2.0	-0.3
Medication: Seretide 50 evohaler	0.6	0.7	1.4	-1.2	0.5	0.8	0.5	1.1	-0.8	1.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.4	0.6	-0.4	1.6	-0.9	-0.6	1.0	-0.2	-0.6
Medication: Aspirin	0.6	0.8	3.7	-0.3	-0.5	1.0	-0.7	-0.0	1.9	0.3	-1.0
Supplements: Vitamin C	0.6	0.7	2.2	0.2	-0.5	-1.0	-0.5	-0.7	1.3	1.5	0.1
Ever had bowel cancer screening	0.6	0.8	2.0	-1.4	-0.6	-0.7	-0.7	-0.6	-0.2	-1.4	-0.6
Friendships satisfaction	0.6	0.7	1.7	-0.0	-1.3	-0.3	-1.1	-1.0	1.1	-0.4	-0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.6	0.6	-0.9	-0.6	-0.6	-0.9	1.0	1.3	-0.9
Fasting Glucose	0.5	0.5	1.3	0.2	1.0	1.2	0.5	0.8	0.8	0.6	-0.3
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.1	0.7	0.9	1.4	-0.0	0.4	-0.8	0.5	0.0
Hypothyroidism (self reported)	0.5	1.1	1.7	-1.2	-0.9	-1.3	-1.1	-1.1	0.4	-1.0	-1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.0	-0.6	0.5	-0.7	-0.4	0.3	-0.8	-0.2	1.7
Ever had hysterectomy (womb removed)	0.5	0.6	1.3	0.3	0.9	-1.2	0.5	1.0	0.7	-0.8	0.2
Diabetes (mother)	0.5	0.6	1.4	-0.8	0.6	1.2	0.6	1.0	0.2	0.9	0.6
Hand grip strength (right)	0.5	1.3	7.7	-2.8	-0.0	-0.3	0.1	0.2	-1.4	0.5	-0.9
Fed-up feelings	0.5	0.9	1.9	1.1	-0.7	-1.4	-0.9	-1.0	-0.2	-0.5	1.1
Hearing difficulty/problems with background noise	0.5	0.8	4.5	0.5	-0.0	-0.3	-0.6	0.5	2.1	0.7	0.2
Had menopause	0.5	0.6	1.0	-0.7	-0.9	-0.5	-0.8	-0.5	1.0	-0.8	-0.9
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.2	-1.0	0.7	-0.0	0.1	1.2	-0.8	0.2	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.0	-0.6	0.0	-1.1	-0.7	-0.4	-1.4	-0.8	0.4
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.8	-0.7	0.9	0.9	0.2	1.3	-0.3	1.0	0.7
Leg fat percentage (right)	0.5	1.7	4.9	0.3	-1.5	0.8	-1.0	-0.5	2.2	-0.8	-1.9
Wheeze or whistling in the chest in last year	0.5	1.0	4.0	-0.0	0.1	-1.2	-0.2	0.6	1.4	2.0	0.0
Medication: Blood pressure	0.5	0.9	3.1	-0.3	-0.1	1.8	1.4	0.8	1.0	0.8	-0.4
Angina (self-reported)	0.5	0.7	1.3	0.5	-1.0	-0.0	-1.1	-1.0	0.9	-0.7	-0.6
Long-standing illness, disability or infirmity	0.5	0.8	2.9	1.3	0.2	-1.7	0.1	-0.2	0.1	1.0	-1.0
Medication for cholesterol	0.5	0.7	2.2	0.1	0.9	1.5	1.2	0.6	-0.6	0.6	0.2
Osteoarthritis (self-reported)	0.5	0.6	2.0	-0.4	-0.3	1.1	0.1	-0.5	1.4	-0.9	-0.7
Medication: Aspirin	0.5	0.6	2.4	-0.3	-0.1	1.3	-0.3	0.2	1.6	0.5	-0.7
Number of self-reported non-cancer illnesses	0.5	1.0	2.5	-1.6	0.7	-1.5	-0.0	1.1	-0.8	-0.0	0.7
Hearing aid user	0.5	0.6	2.1	1.0	0.7	1.4	0.7	0.4	-0.6	0.1	0.3
Depression (Nagel 2018)	0.4	0.6	3.5	0.3	0.1	-0.7	0.1	-0.2	-0.4	-0.5	1.9
Breast Cancer	0.4	0.9	3.9	-1.1	0.2	-0.5	-0.5	0.1	-2.0	0.2	1.3
Ovarian Cancer	0.4	0.6	1.6	-1.3	0.7	-0.8	0.6	0.4	-0.8	0.8	0.2
Schizophrenia (2014)	0.4	0.9	2.2	0.9	-1.0	-0.4	-1.5	-1.1	1.3	-0.3	-0.2
Waist Hip Ratio (WHR)	0.4	1.8	8.1	0.6	1.4	-0.0	1.0	1.2	-0.8	2.9	-1.1
Cardiovascular Disease	0.4	1.4	3.6	-0.5	1.0	0.3	1.0	1.6	-0.3	1.9	1.6
Chronotype (morning person)	0.4	1.0	3.7	-1.9	-0.2	-1.1	-0.5	0.8	0.3	0.4	1.3
Number of treatments/medications taken	0.4	0.7	3.0	-1.7	0.3	-1.2	-0.0	0.1	0.3	0.6	-0.4
Hearing difficulty/problems: Yes	0.4	0.7	3.0	1.7	0.5	-0.6	-0.3	0.2	0.8	0.7	-0.6
Angina	0.4	0.6	1.0	0.8	-0.7	0.2	-1.0	-0.7	1.0	-0.6	-0.6
Current tobacco smoking	0.4	0.7	2.5	1.1	-0.1	-0.3	-0.2	-0.8	1.6	-0.8	-0.3
Average weekly fortified wine intake	0.4	0.5	2.4	-0.3	-0.1	0.0	0.6	0.5	0.9	0.5	-1.5
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.0	0.3	1.0	-0.9	0.7	0.2	-1.0	0.0	0.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.0	-0.6	1.0	0.2	0.9	0.8	-1.0	0.3	-0.1
Alcohol usually taken with meals	0.4	0.6	1.6	-1.3	0.2	0.6	1.2	0.5	0.2	0.6	-1.0
Financial difficulties in last 2 years	0.4	0.6	2.9	0.9	0.2	0.8	0.1	-0.1	-1.7	-0.0	0.7
Alcohol intake versus 10 years previously	0.4	0.5	2.5	0.4	0.7	1.6	1.0	0.3	0.0	0.1	-0.1
Pulse rate	0.4	0.7	4.0	-2.0	-0.5	0.6	0.1	-0.6	-0.6	-0.5	-0.3
Noisy workplace	0.4	0.6	1.9	0.9	-0.2	0.9	0.2	-0.6	0.5	-1.4	-0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.1	-0.4	0.9	0.1	2.0	1.1	-0.2	0.7	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.9	-0.9	0.3	0.7	0.7	0.9	-0.3	0.9	0.6
Prospective memory result	0.4	0.5	1.8	1.1	-0.5	0.6	-0.0	0.0	1.3	-0.5	0.3
Lung cancer (father)	0.4	0.4	1.6	0.9	0.4	0.4	0.0	0.5	0.7	1.2	-0.4
Exposure to tobacco smoke at home	0.4	0.5	1.5	0.7	-0.1	1.1	-0.5	0.1	-0.1	-0.5	1.2
Gout (self-reported)	0.4	0.5	3.1	0.6	0.3	1.8	0.7	-0.2	-0.2	-0.2	0.4
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.8	-1.4	0.3	-0.7	0.7	0.3	0.6	0.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.6	1.2	0.8	-0.1	0.6	0.1	-0.1	0.6	-0.8
Emphysema/chronic bronchitis	0.4	0.5	1.6	-0.2	0.2	-0.9	-0.8	0.1	0.8	1.3	-0.3
Knee pain experienced in last month	0.4	0.7	2.1	-1.1	0.2	-1.4	-0.4	0.3	-0.8	1.1	0.2
Qualifications: nursing, teaching	0.4	0.6	3.2	-1.8	-0.5	0.2	0.1	-0.6	-0.6	-0.5	-0.4
Breast cancer (self-reported)	0.4	0.5	2.5	1.6	-0.0	-0.7	-0.6	-0.1	0.8	0.1	-0.5
Medication: Lisinopril	0.4	0.5	1.8	-0.1	-0.2	1.3	0.1	0.2	0.4	0.6	-1.3
Illnesses of father: High blood pressure	0.4	0.5	1.9	-0.7	-0.3	1.4	-0.9	-0.3	-0.3	1.0	-0.1
Leg fat percentage (left)	0.4	1.4	3.9	0.2	-1.5	0.5	-1.0	-0.6	2.0	-0.6	-1.7
Risk taking	0.4	0.6	2.0	-0.8	-0.7	-1.4	-0.7	-0.8	-0.7	0.6	-0.1
Unable to work because of sickness or disability	0.4	0.5	1.2	1.1	0.4	1.1	-0.6	-0.2	-0.7	0.4	0.6
Impedance of whole body	0.4	1.8	4.7	1.4	1.9	1.0	2.2	1.5	0.6	0.7	-0.8
Depressed Affect (Nagel 2018)	0.3	0.7	3.2	-0.5	-0.1	-1.3	0.3	-0.1	-0.7	0.3	1.8
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.7	-1.0	0.6	0.6	1.1	1.3	-0.5	0.9	0.9
Worry (Nagel 2018)	0.3	0.5	1.3	-0.7	0.4	-0.2	0.9	0.2	1.1	-0.5	1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.1	-0.7	0.6	0.6	1.4	1.4	-0.2	0.3	-0.0
HbA1C	0.3	0.4	1.0	-0.0	0.6	1.0	0.3	0.1	-0.1	0.8	-1.0
Blood White Count	0.3	1.9	4.9	1.6	-2.0	0.9	-1.1	-2.2	1.0	-0.7	-0.4
Neuroticism	0.3	0.7	2.0	-0.7	-0.8	-0.9	-0.0	-1.0	0.6	-1.4	0.1
Hand grip strength (left)	0.3	0.9	3.1	-1.8	-0.5	-0.3	-0.7	-0.8	-0.2	0.0	-1.6
Average weekly spirits intake	0.3	0.3	0.6	-0.7	0.6	0.8	0.4	0.5	0.4	0.1	-0.8
Impedance of leg (right)	0.3	1.5	4.3	2.1	-0.1	0.8	-0.7	-0.5	1.7	-0.7	-1.6
Trunk fat percentage	0.3	1.1	2.0	0.2	0.6	1.1	1.3	1.4	0.7	1.1	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.0	0.2	-0.2	-1.0	-0.4	-0.6	-0.1	-0.5	0.9
Qualifications: CSEs or equivalent	0.3	0.4	1.3	-1.1	-0.2	0.8	0.1	-0.1	-0.3	-0.3	-1.0
Serious illness, injury or assault to yourself	0.3	0.3	1.1	1.1	0.6	-0.1	-0.3	-0.0	0.8	-0.3	0.7
Trunk fat mass	0.3	1.4	2.7	-0.6	0.6	1.0	1.5	1.6	0.5	1.4	-1.5
Nervous feelings	0.3	0.6	1.8	-0.4	0.9	-0.9	0.8	0.8	-0.4	0.3	1.3
Diabetes (self-reported)	0.3	0.5	1.3	0.3	-0.7	-0.4	-0.8	-0.7	1.1	0.1	-0.8
Father’s age at death	0.3	0.5	1.2	-0.3	-0.4	0.3	0.4	-0.8	-1.1	-1.1	-0.5
Peak expiratory flow (PEF)	0.3	0.6	3.1	1.8	0.0	0.5	-1.0	-0.2	-0.0	-0.4	0.5
Medication: Amlodipine	0.3	0.4	2.0	-0.3	-0.6	-1.4	-0.3	-0.5	-0.5	-0.4	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.5	-0.7	0.3	0.2	0.1	-0.4	-1.2	0.3	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.9	-0.8	0.1	-0.7	0.1	-0.1	0.1	-0.5	0.9
Qualifications: College or University degree	0.3	1.1	4.1	-1.1	1.0	-0.4	2.0	0.9	-1.1	-0.1	-0.1
Medication: Ibuprofen	0.3	0.4	1.6	-0.6	0.1	-0.7	-0.4	-0.2	-1.3	-0.6	0.3
Suffer from ‘nerves’	0.3	0.5	2.3	0.2	0.1	-0.3	0.6	0.3	1.5	-1.1	0.0
Age at last live birth	0.3	0.5	1.1	1.0	-0.3	0.9	0.7	0.1	0.4	0.5	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.7	-0.0	0.0	0.2	-0.4	0.3	-1.0	0.5	1.3
Whole body fat-free mass	0.3	1.9	7.9	-2.8	0.7	-0.0	1.3	1.4	-0.9	1.4	-0.7
Mood swings	0.3	0.5	1.8	-0.3	-0.3	-0.7	-0.4	-0.7	-0.4	-0.9	1.3
Mineral and other dietary supplements	0.3	0.4	1.2	0.3	1.1	0.3	0.4	0.6	-0.7	-0.3	0.9
Smoking status: Current	0.3	0.5	1.8	0.7	-0.3	-0.5	-0.4	-0.8	1.3	-0.8	-0.3
Whole body water mass	0.3	1.8	7.6	-2.8	0.6	0.0	1.2	1.4	-0.7	1.3	-0.7
Eye problems/disorders: Glaucoma	0.3	0.4	0.9	-0.5	-1.0	0.5	-0.0	-0.8	0.3	-0.8	-0.4
High cholesterol (Self-reported)	0.3	0.6	1.7	0.2	-0.6	-1.3	-0.9	-0.4	0.7	0.9	-0.2
Basal metabolic rate	0.3	1.8	6.4	-2.5	0.7	0.2	1.4	1.6	-0.7	1.4	-0.8
Irritability	0.3	0.5	1.6	-0.3	-0.5	1.3	-0.7	-1.1	0.4	0.5	0.1
Heart disease (siblings)	0.3	0.4	2.2	-0.1	-0.7	-0.3	-0.3	-0.2	1.5	-0.3	-0.1
Neuroticism (Nagel 2018)	0.2	0.5	1.0	-1.0	-0.7	-0.6	0.1	-0.7	0.7	-0.3	1.0
Schizophrenia (2018)	0.2	0.5	1.4	0.3	-0.5	-0.9	-1.2	-0.7	0.6	0.4	0.1
Age at First Birth	0.2	0.2	1.3	1.1	0.2	-0.4	0.0	-0.1	0.2	0.3	0.4
Triglycerides	0.2	0.3	0.9	-0.0	-0.7	-0.6	-1.0	-0.7	0.2	-0.2	0.0
Blood Eosinophil Count	0.2	1.6	8.0	-2.8	0.0	-1.8	0.7	0.9	0.2	-0.6	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	2.0	0.6	0.2	0.1	0.3	-0.0	-0.8	1.4	-0.4
Sitting height	0.2	1.1	2.2	-1.5	0.5	-1.3	0.8	0.6	-0.9	0.6	-1.5
Impedance of leg (left)	0.2	0.9	3.7	1.9	-0.1	0.3	-0.7	-0.5	1.3	-0.5	-1.0
Waist circumference	0.2	0.7	1.7	-1.3	0.1	0.2	0.7	1.1	0.1	1.1	-0.9
Hair/balding pattern: Pattern 2	0.2	0.2	0.9	-0.4	-0.5	-0.9	0.1	0.4	-0.0	-0.5	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.4	-0.0	0.3	-0.1	0.5	0.3	-0.7	1.6	-1.0
Qualifications: None of the above	0.2	0.5	1.7	1.3	0.3	-0.6	-0.4	-0.1	0.9	-0.5	0.7
Medication: Ramipril	0.2	0.3	1.0	-0.5	0.0	-0.4	1.0	0.2	0.9	-0.4	-0.1
Medication: Simvastatin	0.2	0.3	0.8	-0.1	-0.3	-0.9	-0.1	0.0	0.9	0.7	-0.0
Weight	0.2	1.2	2.7	-1.6	0.4	0.5	1.2	1.5	0.2	1.2	-1.3
Arm fat percentage (right)	0.2	0.8	1.4	0.3	0.4	1.0	1.2	1.1	1.2	0.7	-0.9
Trunk fat-free mass	0.2	1.3	6.5	-2.5	0.3	-0.2	0.8	1.1	-0.4	1.0	-1.0
Hip circumference	0.2	0.8	3.3	-1.8	-0.5	0.1	0.3	0.7	1.0	0.5	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.1	1.0	0.2	-0.4	0.3	0.1	0.6	-0.9	0.4
Falls in the last year	0.2	0.3	0.9	-0.9	0.3	0.3	0.7	0.6	-0.3	-0.1	0.5
Number of live births	0.2	0.3	0.7	-0.4	-0.8	-0.9	-0.4	-0.1	-0.7	-0.6	0.5
Medication: Cholesterol lowering	0.2	0.4	2.0	0.2	-0.1	-0.3	-0.2	-0.4	0.5	1.4	-0.5
Trunk predicted mass	0.2	1.4	7.0	-2.6	0.3	-0.2	0.9	1.1	-0.5	1.0	-1.0
Tense / ‘highly strung’	0.2	0.3	1.4	0.1	-0.0	-0.7	-0.5	-0.1	0.3	-0.6	1.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.6	0.3	0.5	0.7	0.3	0.3	0.4	0.5	0.2
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.5	0.1	0.3	-0.7	-0.6	-0.1	-1.2	-0.6	0.2
Body fat percentage	0.2	0.8	1.9	0.3	0.1	1.1	0.8	1.0	1.2	0.5	-1.4
Arm fat-free mass (right)	0.2	1.3	7.7	-2.8	-0.0	-0.3	0.3	0.9	-0.6	0.9	-0.6
Age at first live birth	0.2	0.4	1.2	1.1	0.4	0.8	0.7	0.3	-0.3	0.4	-0.2
Whole body fat mass	0.2	0.7	1.8	-0.6	0.1	0.8	0.9	1.1	0.8	0.8	-1.4
Leg fat mass (right)	0.2	0.7	2.5	-0.4	-0.6	0.6	-0.1	0.3	1.3	0.1	-1.6
Arm predicted mass (right)	0.2	1.1	7.0	-2.6	-0.2	-0.6	-0.2	0.6	-0.9	0.7	-0.1
Arm fat percentage (left)	0.2	0.9	2.6	0.0	0.7	1.0	1.6	1.5	0.6	1.0	-0.4
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	1.1	0.1	-0.2	0.5	-0.2	0.6	0.2	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.3	1.2	-0.2	0.5	-0.1	0.3	0.8	0.1	-0.2	1.1
Average weekly champagne plus white wine intake	0.2	0.3	1.4	0.2	-0.1	-0.1	-0.7	-0.4	-1.2	-0.0	0.1
Miserableness	0.2	0.3	0.8	0.9	0.6	-0.7	0.2	0.3	-0.7	0.1	0.7
Wears glasses or contact lenses	0.2	0.2	0.6	-0.6	-0.6	-0.0	-0.1	-0.4	0.4	-0.4	-0.8
Medication: Atorvastatin	0.2	0.3	1.2	0.6	0.4	0.6	0.5	0.0	0.2	1.1	0.1
Arm fat-free mass (left)	0.2	1.2	7.4	-2.7	-0.6	-0.6	-0.4	0.3	-0.1	0.3	-0.9
Cholesterol lowering medication	0.2	0.3	1.3	-0.1	0.3	-0.7	-0.4	0.3	-0.0	0.7	1.1
Supplements: Calcium	0.2	0.2	0.5	-0.7	0.1	-0.4	0.2	-0.5	-0.3	0.4	-0.5
Leg fat mass (left)	0.2	0.6	2.4	-0.5	-0.6	0.6	0.0	0.3	1.3	0.2	-1.5
Arm predicted mass (left)	0.2	0.8	5.2	-2.3	-0.5	-0.3	-0.3	0.4	-0.2	0.3	-0.7
LDL Cholesterol	0.1	0.1	0.2	-0.2	0.4	-0.4	-0.5	-0.1	-0.3	0.4	0.0
Blood Platelet Count	0.1	1.3	2.2	-1.4	1.2	0.6	1.5	1.5	-1.0	0.3	0.7
Heel T-Score	0.1	1.1	3.1	-0.4	-0.9	1.0	-0.2	-0.3	0.7	1.7	-1.8
BMI	0.1	0.4	1.5	-0.6	-0.8	0.3	-1.2	0.1	-0.2	0.3	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	0.1	-0.7	-0.4	-0.8	-0.6	0.1	-0.1	-0.2
Hair Pigment	0.1	1.7	5.8	0.7	-1.3	-1.1	-2.4	-1.6	-0.2	-1.4	0.5
Tanning	0.1	1.7	4.9	-1.6	-0.3	-1.4	-0.6	-0.8	-2.2	0.5	-1.7
Medication: Metformin	0.1	0.1	0.6	-0.2	-0.3	-0.8	-0.0	-0.3	-0.1	0.5	0.1
High blood pressure	0.1	0.1	0.6	-0.3	-0.2	0.1	0.4	0.3	0.8	0.0	-0.3
Body mass index (BMI)	0.1	0.3	1.1	-0.2	-1.1	0.1	-0.9	-0.3	0.8	-0.2	-0.3
Fluid intelligence score	0.1	0.2	0.5	0.1	0.2	-0.7	0.5	0.4	-0.4	0.4	-0.5
Worrier / anxious feelings	0.1	0.1	0.5	-0.2	0.4	-0.3	0.7	-0.3	0.1	-0.4	0.2
Arm fat mass (right)	0.1	0.4	0.9	-0.5	0.1	0.5	0.7	0.9	0.6	0.8	-0.9
Hair/balding pattern: Pattern 4	0.1	0.3	1.0	1.0	0.1	-0.7	-0.4	-0.4	-0.9	-0.1	-0.4
Pulse wave reflection index	0.1	0.1	0.2	-0.0	0.2	-0.4	-0.0	0.5	-0.5	0.4	-0.1
Glaucoma (self-reported)	0.1	0.1	0.3	0.3	-0.5	0.4	0.3	-0.3	0.1	-0.6	-0.1
Hypertension (Self-reported)	0.1	0.2	0.6	-0.4	0.1	0.3	0.8	0.7	0.6	0.3	-0.2
Diabetes diagnosed by doctor	0.1	0.1	0.2	0.4	-0.1	-0.1	-0.4	0.0	0.5	0.3	0.2
Osteoporosis (self-reported)	0.1	0.1	0.7	-0.2	-0.1	-0.2	0.1	-0.8	-0.1	-0.6	-0.1
Arm fat mass (left)	0.1	0.5	1.2	-0.7	0.2	0.4	0.9	1.1	0.4	0.9	-0.8
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.6	-0.5	0.3	-0.8	-0.1	-0.2	-0.2	0.4	0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.4	0.1	-0.0	0.3	-0.6	-0.3	0.4	0.0	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.2	-0.1	0.4	0.1	0.1	0.0	-0.3	0.2	-0.1

Hub : Genes

SHKBP1

Models

Trait associations