[Hub]/) : Traits : Lung FVC : ← →

chr2:177,451,264-180,139,951

Best TWAS P=7.36e-21 · Best GWAS P=1.9e-20 conditioned to 0.828

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TTC30A	0.12	0.09	lasso	8	0.09	5.4e-11	-9.1	-8.9	5.0e-19	0.96	0.00	1.00	FALSE
2	GTEx	Adrenal Gland	AC073834.3	0.12	0.10	lasso	2	0.07	1.5e-03	-9.1	-9.0	1.7e-19	0.95	0.03	0.85	FALSE
3	GTEx	Artery Aorta	AC073834.3	0.11	0.10	enet	11	0.12	3.7e-07	-8.8	-9.1	1.0e-19	0.92	0.03	0.96	FALSE
4	GTEx	Artery Aorta	RP11-171I2.2	0.12	0.00	enet	5	0.00	4.2e-01	6.8	-6.5	9.5e-11	0.04	0.01	0.92	FALSE
5	GTEx	Artery Tibial	RP11-171I2.2	0.08	0.05	lasso	3	0.06	1.8e-05	6.8	-6.5	5.9e-11	0.01	0.00	0.99	FALSE
6	GTEx	Artery Tibial	RP11-171I2.5	0.07	0.04	enet	5	0.03	1.9e-03	5.5	-6.5	7.1e-11	0.02	0.02	0.94	FALSE
7	GTEx	Brain Cerebellum	TTC30A	0.13	0.13	lasso	2	0.14	5.8e-05	-7.0	-7.7	9.6e-15	0.84	0.06	0.83	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	AC073834.3	0.16	0.01	enet	33	0.05	2.1e-02	-8.2	-7.5	5.2e-14	0.61	0.23	0.47	FALSE
9	GTEx	Breast Mammary Tissue	AC073834.3	0.13	0.12	lasso	4	0.08	4.9e-05	-8.1	-8.5	1.4e-17	0.83	0.44	0.53	FALSE
10	GTEx	Breast Mammary Tissue (Male)	AC073834.3	0.22	0.13	enet	18	0.07	8.7e-03	-6.2	-8.5	2.1e-17	0.83	0.16	0.52	FALSE
11	GTEx	Breast Mammary Tissue (Female)	AC073834.3	0.04	-0.01	lasso	4	-0.01	6.0e-01	-8.8	-8.8	1.3e-18	0.87	0.04	0.08	FALSE
12	GTEx	Cells Transformed fibroblasts	AC073834.3	0.13	0.16	lasso	2	0.16	6.7e-12	-9.1	-9.3	9.6e-21	0.96	0.01	0.99	FALSE
13	GTEx	Cells Transformed fibroblasts	RP11-171I2.5	0.09	0.00	enet	22	0.00	5.7e-01	-3.4	-5.6	2.7e-08	0.04	0.10	0.16	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	AC073834.3	0.10	0.09	lasso	3	0.06	3.7e-03	-9.3	-9.0	2.7e-19	0.96	0.01	0.96	FALSE
15	GTEx	Esophagus Mucosa	AC073834.3	0.06	0.07	lasso	3	0.06	8.3e-05	-9.1	-9.3	1.7e-20	0.99	0.00	0.99	FALSE
16	GTEx	Esophagus Muscularis	AGPS	0.06	0.03	lasso	3	0.02	2.7e-02	-8.7	-9.1	6.6e-20	0.95	0.03	0.95	FALSE
17	GTEx	Esophagus Muscularis	AC073834.3	0.06	0.02	lasso	3	0.01	5.6e-02	-7.0	-7.8	4.1e-15	0.84	0.05	0.75	FALSE
18	GTEx	Heart Left Ventricle	AC073834.3	0.09	0.03	enet	14	0.03	6.8e-03	-8.5	-7.2	4.3e-13	0.71	0.11	0.78	FALSE
19	GTEx	Nerve Tibial	AGPS	0.16	0.04	enet	11	0.06	3.8e-05	-5.9	-6.6	5.1e-11	0.62	0.72	0.14	FALSE
20	GTEx	Nerve Tibial	AC073834.3	0.09	0.05	lasso	2	0.03	2.1e-03	-9.1	-8.9	3.8e-19	0.96	0.01	0.98	FALSE
21	GTEx	Ovary	AGPS	0.22	0.04	lasso	7	0.02	1.0e-01	-6.4	-5.4	8.3e-08	0.53	0.14	0.19	FALSE
22	GTEx	Pituitary	AC073834.3	0.18	0.18	lasso	7	0.12	7.2e-04	-8.1	-8.7	2.6e-18	0.79	0.08	0.75	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	RP11-171I2.2	0.14	0.04	lasso	4	0.04	2.5e-03	6.8	-6.8	1.0e-11	0.06	0.00	0.99	TRUE
24	GTEx	Skin Sun Exposed Lower leg	AC073834.3	0.07	0.07	lasso	3	0.06	9.5e-06	-9.1	-9.2	5.1e-20	0.96	0.01	0.99	FALSE
25	GTEx	Spleen	AC074286.1	0.23	0.17	lasso	4	0.14	1.8e-04	-6.4	5.3	1.4e-07	-0.52	0.25	0.11	FALSE
26	GTEx	Spleen	AC073834.3	0.17	0.08	enet	22	0.08	3.6e-03	-8.2	-8.9	3.8e-19	0.77	0.10	0.69	FALSE
27	GTEx	Testis	AC073834.3	0.24	0.23	lasso	7	0.26	4.8e-12	-9.1	-9.4	7.4e-21	0.94	0.01	0.99	TRUE
28	GTEx	Thyroid	AC073834.3	0.12	0.09	enet	9	0.09	1.4e-07	-8.8	-8.4	5.7e-17	0.92	0.02	0.98	FALSE
29	GTEx	Thyroid	RP11-171I2.2	0.12	0.04	lasso	6	0.05	7.5e-05	-4.1	-5.8	5.3e-09	0.01	0.33	0.65	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	PDE11A	0.05	0.04	blup	622	0.04	1.9e-06	-6.6	-7.0	3.4e-12	0.67	0.55	0.41	FALSE
31	YFS	Blood	AGPS	0.02	0.01	bslmm	504	0.01	6.5e-05	-8.3	7.5	4.4e-14	-0.69	0.12	0.73	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	PDE11A	0.07	0.02	blup	282	0.04	8.7e-06	-7.3	-7.4	1.4e-13	0.70	0.24	0.70	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	TTC30A	0.05	0.03	enet	23	0.04	4.1e-05	-9.1	-6.0	2.6e-09	0.66	0.01	0.98	FALSE
34	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC100130691	0.14	0.10	lasso	7	0.10	1.5e-07	-6.9	-5.6	1.7e-08	0.28	0.88	0.09	FALSE
35	The Cancer Genome Atlas	Stomach Adenocarcinoma	LOC100130691	0.15	0.07	blup	70	0.12	2.5e-09	-8.3	-6.5	8.3e-11	0.41	0.04	0.96	FALSE