[Hub]/) : Traits : Lung FVC : ← →

chr5:147,063,674-150,635,429

Best TWAS P=1.19e-17 · Best GWAS P=1.74e-15 conditioned to 0.719

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ABLIM3	0.15	0.15	enet	20	0.16	7.6e-19	-7.8	7.5	7.1e-14	-0.84	0.04	0.96	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FBXO38	0.05	0.01	blup	489	0.02	1.5e-03	4.9	-5.3	9.4e-08	0.02	0.79	0.01	FALSE
3	CommonMind	Brain Pre-frontal Cortex	HTR4	0.06	0.03	lasso	4	0.03	4.3e-05	4.7	6.9	7.2e-12	-0.03	0.64	0.04	TRUE
4	GTEx	Adipose Subcutaneous	AFAP1L1	0.12	0.01	lasso	4	0.01	8.3e-02	-5.8	-5.3	1.1e-07	0.73	0.03	0.92	FALSE
5	GTEx	Brain Cerebellum	ABLIM3	0.50	0.34	lasso	6	0.40	9.3e-13	-7.9	7.9	2.7e-15	-0.96	0.01	0.99	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	AFAP1L1	0.15	0.12	lasso	7	0.11	8.0e-04	4.9	5.1	2.9e-07	-0.16	0.26	0.13	FALSE
7	GTEx	Cells Transformed fibroblasts	AFAP1L1	0.17	0.10	enet	16	0.15	4.7e-11	-5.8	-7.0	3.3e-12	0.92	0.06	0.94	FALSE
8	GTEx	Muscle Skeletal	AFAP1L1	0.24	0.17	enet	19	0.23	1.7e-22	-5.8	-5.9	4.0e-09	0.68	1.00	0.00	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	NDST1	0.06	0.05	lasso	7	0.04	1.7e-05	5.3	-5.3	1.3e-07	-0.02	0.00	1.00	TRUE
10	ROSMAP	Brain Pre-frontal Cortex	ABLIM3	0.32	0.34	bslmm	589	0.33	1.1e-43	-7.8	8.6	1.2e-17	-0.90	0.04	0.96	TRUE
11	YFS	Blood	ABLIM3	0.03	0.01	blup	575	0.02	2.4e-06	-5.7	-7.0	2.1e-12	0.72	0.09	0.90	FALSE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	AFAP1L1	0.04	0.03	blup	84	0.03	2.3e-03	-7.9	-6.5	6.8e-11	0.87	0.01	0.96	FALSE
13	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	AFAP1L1	0.12	0.03	enet	17	0.04	3.4e-03	-6.4	-5.5	4.0e-08	0.63	0.01	0.83	FALSE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	ABLIM3	0.25	0.02	blup	111	0.11	3.4e-04	-4.2	6.4	1.9e-10	-0.72	0.02	0.48	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AFAP1L1	0.04	0.01	blup	84	0.01	7.8e-03	-6.4	-6.7	1.9e-11	0.90	0.03	0.86	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AFAP1L1	0.27	0.12	lasso	6	0.14	2.1e-08	-5.6	-6.3	3.2e-10	0.80	0.20	0.80	FALSE
17	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	AFAP1L1	0.09	0.01	blup	84	0.04	8.3e-03	-7.8	-5.5	4.6e-08	0.78	0.02	0.58	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	AFAP1L1	0.02	0.01	blup	84	0.01	6.3e-03	-5.8	-6.9	5.7e-12	0.89	0.01	0.92	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AFAP1L1	0.02	0.02	blup	84	0.02	4.3e-03	-7.9	-7.1	1.2e-12	0.95	0.02	0.94	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AFAP1L1	0.08	0.04	blup	85	0.05	4.2e-04	-5.6	-6.6	5.7e-11	0.86	0.01	0.93	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	AFAP1L1	0.07	0.05	enet	8	0.06	6.3e-07	-5.8	-7.2	4.6e-13	0.82	0.10	0.90	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	SH3TC2	0.30	0.30	lasso	6	0.38	2.7e-41	5.9	5.7	1.1e-08	-0.20	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Rectum Adenocarcinoma	FBXO38	0.13	0.17	enet	16	0.15	2.3e-04	5.3	-5.2	2.2e-07	0.01	0.02	0.88	FALSE
24	The Cancer Genome Atlas	Stomach Adenocarcinoma	AFAP1L1	0.05	0.01	blup	83	0.03	1.5e-03	-7.9	-5.8	7.2e-09	0.75	0.01	0.75	FALSE