TWAS hub - SH3TC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0831	0.0220	5.9e-08	0.056	0.062	0.053	0.067	0.058	9.5e-09	1.2e-09	1.9e-08	2.8e-10	4.3e-09
2	TCGA	Breast Invasive Carcinoma	0.0260	0.0109	1.1e-03	0.002	0.013	0.015	NA	0.009	8.7e-02	9.0e-04	2.9e-04	NA	5.5e-03
3	TCGA	Prostate Adenocarcinoma	0.3021	0.0460	0.0e+00	0.297	0.325	0.370	NA	0.376	2.0e-31	9.8e-35	1.4e-40	NA	2.7e-41

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse wave Arterial Stiffness index	4.8	5.5	8.9	-1.4	-3.0	-2.4
Lung FVC	4.7	24.2	32.6	4.4	4.6	5.7
Breast Cancer	4.6	11.1	13.3	-3.6	-3.1	-3.2
Pulse wave peak to peak time	4.5	5.3	8.8	1.3	3.0	2.3
Depression (Nagel 2018)	4.3	6.5	9.9	-2.8	-1.3	-3.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.2	8.9	10.2	3.2	3.2	2.5
Peak expiratory flow (PEF)	4.0	9.4	11.0	3.3	2.5	3.3
Forced expiratory volume in 1-second (FEV1), Best measure	3.8	12.0	14.1	3.6	3.0	3.8
Number of operations (self-reported)	3.7	5.6	11.0	-3.3	-1.0	-2.2
Forced expiratory volume in 1-second (FEV1)	3.5	11.7	14.9	3.3	3.1	3.9
Bilateral oophorectomy (both ovaries removed)	3.4	3.9	5.0	1.7	2.0	2.2
Emphysema/chronic bronchitis	3.3	3.7	4.9	-1.4	-2.2	-2.1
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.5	6.0	-2.5	-0.9	-2.0
HbA1C	3.0	3.4	5.5	-1.8	-2.3	-1.2
Nervous feelings	3.0	5.6	8.3	1.2	2.9	2.6
Hearing difficulty/problems with background noise	3.0	4.8	5.5	-2.0	-2.2	-2.3
Medication: Cholesterol lowering	3.0	4.6	5.9	-2.1	-1.8	-2.4
Hand grip strength (right)	2.8	7.7	8.3	2.8	2.6	2.9
Pulse wave reflection index	2.7	3.4	6.5	-0.9	-2.5	-1.7
Lung FEV1/FVC ratio	2.5	12.7	31.4	5.6	2.1	1.5
Forced vital capacity (FVC)	2.4	9.2	14.7	2.3	2.7	3.8
Noisy workplace	2.4	3.0	4.0	1.4	2.0	1.8
Forced vital capacity (FVC), Best measure	2.4	8.8	13.8	2.6	2.4	3.7
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	4.1	-2.0	-1.5	-1.7
Hand grip strength (left)	2.3	6.1	7.7	1.9	2.8	2.6
Alcohol drinker status: Never	2.3	2.8	3.6	1.9	1.9	1.2
Alcohol drinker status: Previous	2.3	2.6	4.5	-1.4	-1.2	-2.1
Crohns Disease (2017)	2.2	4.8	6.6	-2.6	-1.6	-2.3
Verbal and Numeric Reasoning (VNR)	2.2	5.2	8.2	-2.0	-1.8	-2.9
Coronary Artery Disease (CAD)	2.2	2.6	3.6	-1.5	-1.9	-1.5
Chronic bronchitis/emphysema (father)	2.2	2.6	3.4	-1.8	-1.6	-1.3
Lung cancer (father)	2.2	2.6	5.3	-1.4	-0.7	-2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.2	3.3	5.0	0.5	2.2	2.2
Pack years of smoking	2.2	3.2	5.6	-0.8	-1.8	-2.4
Depressed Affect (Nagel 2018)	2.0	4.1	6.1	-2.5	-0.7	-2.4
Wheeze or whistling in the chest in last year	2.0	3.6	8.0	-2.8	-0.4	-1.6
Prospective memory result	1.9	2.3	3.5	1.9	1.3	1.4
Commuting to job workplace: Car/motor vehicle	1.9	2.1	2.7	-1.6	-1.6	-1.1
Friendships satisfaction	1.9	2.4	3.6	0.9	1.7	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.3	5.3	-1.3	-0.2	-2.3
Had other major operations	1.8	2.2	3.7	-1.9	-1.0	-1.5
Suffer from ‘nerves’	1.8	2.9	5.4	0.4	2.3	1.7
Chest pain or discomfort	1.8	2.6	3.5	-1.5	-1.9	-1.4
Smoking status: Previous	1.8	2.6	3.1	-1.6	-1.8	-1.5
Systolic Blood Pressure	1.7	8.7	20.2	4.5	-0.2	2.4
Frequency of depressed mood in last 2 weeks	1.7	2.4	3.5	-1.9	0.4	-1.9
Falls in the last year	1.7	2.3	3.0	-1.7	-1.2	-1.6
Alzheimer’s Disease (including proxy)	1.6	2.3	2.8	1.6	1.7	1.3
Illnesses of siblings	1.6	2.3	3.3	1.2	1.8	1.5
Exposure to tobacco smoke outside home	1.6	2.2	4.4	-2.1	-1.2	-0.8
Unable to work because of sickness or disability	1.6	2.0	2.4	-1.5	-1.3	-1.5
Wears glasses or contact lenses	1.5	1.7	2.8	1.2	1.7	1.0
Illnesses of father: High blood pressure	1.5	1.9	5.0	-0.4	-2.2	-0.7
Risk taking	1.5	2.3	3.5	-1.9	-1.1	-1.4
Bipolar Disorder or Schizophrenia	1.4	3.3	5.2	-1.5	-1.6	-2.3
Average weekly spirits intake	1.4	1.7	2.5	1.0	1.6	1.3
Father’s age at death	1.4	1.8	2.4	0.9	1.5	1.6
Neck or shoulder pain in last month	1.4	2.0	3.4	-0.9	-1.3	-1.9
Medication: Ibuprofen	1.4	1.6	2.4	-1.6	-1.0	-1.3
Ever had bowel cancer screening	1.4	1.7	3.0	-1.7	-1.2	-0.8
Fractured/broken bones in last 5 years	1.4	1.8	4.5	-2.1	-0.6	-0.8
Ovarian Cancer	1.3	1.7	2.4	1.5	1.5	0.8
Medication for hormone replacement therapy	1.3	1.5	2.7	0.9	0.9	1.6
Depression (self-reported)	1.3	1.5	2.6	-1.6	-0.8	-1.2
Exposure to tobacco smoke at home	1.3	1.4	4.0	0.2	-2.0	-0.4
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	3.4	1.1	1.2	1.9
Shortness of breath walking on level ground	1.3	1.6	2.0	-1.4	-1.0	-1.3
Had major operations	1.3	1.5	2.8	-1.3	-0.3	-1.7
Loneliness, isolation	1.3	1.7	3.9	-1.1	-0.2	-2.0
Ever taken oral contraceptive pill	1.3	1.4	1.9	-1.4	-1.1	-1.0
Lupus	1.2	1.8	2.7	-1.4	-1.6	-0.9
Systolic blood pressure, automated reading	1.2	3.4	8.1	2.8	0.3	1.4
Diabetes (father)	1.2	1.5	2.9	1.1	-0.5	1.7
Fed-up feelings	1.2	2.2	3.7	-1.7	-0.5	-1.9
Serious illness, injury or assault to yourself	1.2	1.5	1.7	-1.1	-1.2	-1.3
Qualifications: None of the above	1.2	2.6	3.0	-1.7	-1.5	-1.6
Medication: Simvastatin	1.2	1.8	2.2	-1.2	-1.3	-1.5
Qualifications: College or University degree	1.2	3.8	4.7	2.0	2.2	1.7
Long-standing illness, disability or infirmity	1.2	1.9	3.3	-1.5	-0.5	-1.8
Medication for cholesterol	1.2	1.8	3.2	-1.8	-0.8	-1.3
Heart attack/myocardial infarction (self-reported)	1.2	1.5	2.5	-0.9	-1.6	-1.0
Hearing difficulty/problems: Yes	1.1	1.6	2.9	-0.9	-1.1	-1.7
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.1	-0.8	-0.9	-1.4
Severe depression (siblings)	1.1	1.3	2.1	-1.4	-0.0	-1.3
Pack years adult smoking proportion	1.1	1.8	2.8	-0.4	-1.5	-1.7
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	1.8	-1.4	-1.1	-1.1
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	1.7	1.3	-1.1	1.2
Gout (self-reported)	1.1	1.6	2.6	0.9	1.6	1.1
High blood pressure (siblings)	1.1	1.6	2.9	-0.9	-1.7	-1.1
Schizophrenia (2018)	1.0	2.1	2.9	-1.0	-1.5	-1.7
Maternal smoking around birth	1.0	1.4	2.7	-1.6	-0.2	-1.2
Heart attack	1.0	1.3	2.6	-0.6	-1.6	-1.0
Happiness	1.0	1.2	2.6	0.8	1.6	0.6
Leg pain on walking	1.0	1.2	1.5	1.2	1.1	1.0
Knee pain experienced in last month	1.0	1.5	2.6	-1.2	-0.8	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	1.9	0.9	0.8	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.8	1.7	-0.8	0.5
Medication: Gliclazide	1.0	1.1	2.7	-0.8	-0.1	-1.6
Hearing aid user	1.0	1.1	1.8	-1.4	-0.3	-1.2
Medication: Blood pressure	1.0	1.8	4.4	2.1	0.5	0.9
Average weekly beer plus cider intake	1.0	1.5	2.6	-1.6	-1.2	-0.5
Alzheimer’s Disease (in mother)	0.9	1.1	1.7	0.9	0.9	1.3
Primary Biliary Cirrhosis	0.9	1.2	3.1	1.8	0.6	0.5
Schizophrenia (2014)	0.9	1.9	3.1	-0.5	-1.5	-1.8
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.7	-1.1	-1.3	-0.2
Number of incorrect matches in round	0.9	1.4	3.1	1.0	0.4	1.8
Financial difficulties in last 2 years	0.9	1.2	1.9	-0.9	-1.4	-1.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.2	1.2	0.3	1.5
Medication: Ramipril	0.9	1.1	1.2	1.0	1.1	1.1
Glaucoma (self-reported)	0.9	1.0	1.5	-1.2	-0.9	-0.9
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.2	-1.0	-0.1	-1.5
Eye problems/disorders: Glaucoma	0.9	1.0	1.3	-1.0	-1.1	-0.9
Supplements: Calcium	0.9	0.9	1.5	-1.2	-0.8	-0.8
Bipolar Disorder (2018)	0.8	1.3	2.3	-1.1	-0.7	-1.5
Intelligence (Savage-Jansen 2018)	0.8	2.5	4.1	-1.2	-1.4	-2.0
Irritable Bowel Disease (IBD)	0.8	1.8	3.4	-1.8	0.0	-1.4
Fasting Glucose	0.8	0.9	1.8	-1.3	-0.5	-0.9
Blood Platelet Count	0.8	9.1	13.2	2.8	3.6	2.5
Fluid intelligence score	0.8	1.6	2.2	-1.0	-1.3	-1.5
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.2	-0.4	-0.7	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.3	-1.0	-1.2	-0.6
Age at first live birth	0.8	1.4	2.4	-0.1	1.5	1.4
Medication: Allopurinol	0.8	1.1	2.5	-0.1	1.6	0.9
Miserableness	0.8	1.4	2.5	-1.3	0.0	-1.6
Major Depression (MDD)	0.7	0.8	1.6	-1.3	-0.8	-0.5
Blood White Count	0.7	5.1	8.9	-1.0	-2.3	-3.0
Relative age of first facial hair	0.7	1.5	2.5	1.6	0.9	1.0
Length of working week for main job	0.7	0.8	1.2	-1.1	-1.0	-0.2
Health satisfaction	0.7	0.9	1.5	1.2	1.0	0.3
Mood swings	0.7	1.2	1.8	-1.4	0.7	-1.1
Average weekly champagne plus white wine intake	0.7	1.0	1.7	-1.3	-0.9	-0.7
Medication: Bendroflumethiazide	0.7	1.1	2.6	-0.4	-0.6	-1.6
Medication: Paracetamol	0.7	1.1	2.6	-1.6	0.4	-0.6
Diastolic blood pressure, automated reading	0.7	2.2	5.9	0.8	-2.4	-0.4
Neuroticism (Nagel 2018)	0.6	1.4	2.9	-1.7	-0.2	-1.1
Blood Red Count	0.6	5.4	9.9	3.1	1.8	1.7
Impedance of leg (right)	0.6	2.9	6.1	1.5	-2.5	0.7
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.3	0.2	1.5	1.3
Medication: Atenolol	0.6	0.8	1.5	-0.8	-0.5	-1.2
Past tobacco smoking	0.6	1.2	1.6	1.0	1.3	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.0	-1.4	0.7	-0.6
Allergy	0.6	1.4	3.1	0.3	-1.8	-1.0
Diabetes (self-reported)	0.6	0.9	1.6	0.3	-1.3	-1.0
Trunk fat-free mass	0.6	3.3	6.7	1.0	2.6	1.4
Impedance of arm (left)	0.6	2.9	8.0	-0.7	-2.8	-0.5
Trunk predicted mass	0.6	3.4	6.9	1.1	2.6	1.5
Breastfed as a baby	0.6	0.7	0.8	-0.9	-0.8	-0.9
Birth weight of first child	0.6	1.1	2.2	0.7	0.8	1.5
Medication: Paracetamol	0.6	1.0	2.6	-1.6	0.2	-0.5
Medication: Seretide 50 evohaler	0.6	0.6	1.7	0.2	1.3	0.5
Asthma (self-reported)	0.6	1.2	1.9	0.4	1.4	1.2
High cholesterol (Self-reported)	0.6	1.0	1.6	-0.9	-0.7	-1.3
Impedance of whole body	0.6	3.0	8.9	0.2	-3.0	0.3
Alzheimer’s Disease (in father)	0.5	0.5	1.0	1.0	0.6	-0.5
Ulcerative Colitis (UC)	0.5	0.9	1.2	-1.1	0.9	-0.9
Prostate Cancer	0.5	0.7	1.1	-1.0	-1.1	-0.4
Age at First Birth	0.5	0.7	1.8	-0.4	-0.3	-1.4
Crohns Disease (2012)	0.5	0.8	2.1	-0.6	-0.3	-1.4
Waist Hip Ratio (WHR)	0.5	2.0	3.8	0.3	-1.9	-1.5
Chronotype (morning person)	0.5	1.3	2.4	-0.8	-0.8	-1.6
Medication: Metformin	0.5	0.8	1.3	0.7	-0.7	-1.2
High blood pressure	0.5	1.3	2.3	1.5	-1.2	-0.1
Impedance of leg (left)	0.5	2.7	6.1	1.1	-2.5	0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.5	1.2	0.4	0.3
Neuroticism score	0.5	1.0	1.7	-1.1	1.3	-0.4
Impedance of arm (right)	0.5	2.2	6.5	-0.1	-2.5	-0.3
Worrier / anxious feelings	0.5	0.9	2.7	0.1	1.6	0.4
Asthma	0.5	1.0	2.0	0.4	1.4	0.9
Loud music exposure frequency	0.5	0.6	1.2	-0.0	-1.1	-0.8
Medication: Amlodipine	0.5	0.7	0.8	-0.8	-0.7	-0.9
Arm fat-free mass (right)	0.5	2.8	5.5	0.9	2.4	1.4
Whole body fat-free mass	0.5	2.6	6.0	0.7	2.4	1.1
Osteoporosis (self-reported)	0.5	0.6	1.8	0.2	1.3	-0.1
Osteoarthritis (self-reported)	0.5	0.7	1.0	-0.9	1.0	-0.4
Illnesses of father: None of the above (group 1)	0.5	0.7	1.9	0.3	1.4	-0.1
Arm fat-free mass (left)	0.5	2.7	4.9	1.1	2.2	1.4
Irritability	0.5	0.8	1.5	-1.2	0.2	-0.9
Ever depressed for a whole week	0.5	0.6	1.3	-0.6	-1.1	-0.3
Myopia	0.5	0.7	0.8	0.8	0.9	0.9
Vascular/heart problems diagnosed by doctor	0.5	1.4	3.3	-1.8	1.0	-0.0
Arm predicted mass (left)	0.5	2.4	4.6	0.9	2.1	1.3
Worry (Nagel 2018)	0.4	0.8	1.2	-0.4	1.1	1.1
Mean Putamen Volume	0.4	0.4	0.7	0.2	0.8	0.7
LDL Cholesterol	0.4	0.7	1.3	0.8	0.1	1.1
Neuroticism (2016)	0.4	0.6	0.9	-0.9	-0.7	-0.7
Ulcerative Colitis	0.4	0.6	1.3	0.4	1.1	0.6
Cardiovascular Disease	0.4	1.4	3.1	1.0	-1.7	0.1
Number of treatments/medications taken	0.4	0.8	1.1	-1.0	-0.8	-0.8
Age when periods started (menarche)	0.4	0.9	1.7	1.3	1.0	0.2
Hair/balding pattern: Pattern 2	0.4	0.5	0.9	0.9	0.8	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.4	0.4	1.2	-0.4
Hair/balding pattern: Pattern 3	0.4	0.7	1.5	-1.2	0.2	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.8	1.2	0.6	1.1	0.9
Tense / ‘highly strung’	0.4	0.7	1.2	-0.9	1.1	-0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.3	-0.0	-1.1	-0.6
Number of full brothers	0.4	0.6	1.6	0.2	1.3	-0.1
Number of children fathered	0.4	0.4	1.1	0.5	1.1	-0.0
Arm predicted mass (right)	0.4	2.1	4.2	0.8	2.1	1.2
Pulse rate, automated reading	0.4	1.3	3.1	1.8	0.8	0.2
Hypertension (Self-reported)	0.4	1.2	2.5	1.6	-1.1	0.2
Eye problems/disorders: Cataract	0.4	0.5	1.3	-1.1	0.2	-0.4
Whole body water mass	0.4	2.3	5.4	0.6	2.3	1.1
Medication: Atorvastatin	0.4	0.5	1.2	-0.4	-0.4	-1.1
Basal metabolic rate	0.4	2.2	4.6	0.8	2.1	1.1
Schizophrenia vs Biploar Disorder	0.3	0.4	0.9	1.0	-0.6	-0.0
Body Mass Index (BMI) (2010)	0.3	0.4	0.5	0.4	0.6	0.7
Rheumatoid Arthritis	0.3	0.4	1.1	0.1	1.0	-0.3
Triglycerides	0.3	0.4	1.0	0.2	-0.5	1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.6	0.5	0.2	0.8
Hypothyroidism (self reported)	0.3	0.6	0.6	0.8	0.8	0.7
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.5	1.2	0.0	0.0
Sensitivity / hurt feelings	0.3	0.5	0.7	-0.8	0.7	-0.4
Ever had hysterectomy (womb removed)	0.3	0.4	0.7	0.2	0.6	0.8
Supplements: Zinc	0.3	0.4	0.5	0.7	-0.7	0.3
Medication: Co-codamol	0.3	0.4	1.0	1.0	-0.0	0.3
High blood pressure (mother)	0.3	0.4	0.8	-0.3	-0.9	-0.5
Had menopause	0.3	0.3	0.6	-0.8	-0.3	-0.6
Pain all over the body in last month	0.3	0.3	0.6	0.5	0.8	0.3
Hip circumference	0.3	1.4	3.4	0.2	1.9	0.9
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.7	0.8	0.3	0.7
Medication: Blood pressure	0.3	0.6	1.1	-0.3	-1.1	-0.7
Migraine (self-reported)	0.3	0.4	0.9	-0.4	0.3	0.9
Alcohol intake frequency.	0.3	0.8	1.6	1.3	0.8	-0.2
Comparative height size at age 10	0.3	1.5	3.2	-0.9	-1.8	0.7
Family relationship satisfaction	0.3	0.3	0.7	0.2	0.8	0.4
Supplements: Vitamin C	0.3	0.4	1.0	0.3	1.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.0	1.0	-0.1	1.0
Diabetes diagnosed by doctor	0.3	0.5	0.6	0.7	-0.6	-0.7
Back pain experienced in last month	0.3	0.4	0.5	0.7	0.5	0.7
Breast cancer (self-reported)	0.3	0.4	0.6	0.7	0.6	0.3
Smoking status: Current	0.3	0.4	1.2	1.1	0.2	0.0
Cholesterol lowering medication	0.3	0.5	1.2	1.1	0.6	-0.1
HDL Cholesterol	0.2	0.3	0.6	0.8	0.1	0.5
Blood Eosinophil Count	0.2	1.7	2.9	0.3	-1.7	-1.5
Neuroticism	0.2	0.5	1.2	-1.1	0.6	0.3
Angina	0.2	0.2	0.3	0.4	-0.5	-0.5
Vitamin and mineral supplements	0.2	0.2	0.2	0.5	-0.5	-0.5
Leg fat-free mass (left)	0.2	1.0	3.0	0.1	1.7	0.4
Townsend deprivation index at recruitment	0.2	0.3	0.7	-0.2	0.2	0.9
Current tobacco smoking	0.2	0.4	1.0	1.0	-0.0	-0.4
Qualifications: CSEs or equivalent	0.2	0.3	0.6	0.3	-0.3	0.8
Stomach or abdominal pain in last month	0.2	0.3	0.8	0.2	-0.9	0.0
Supplements: Glucosamine	0.2	0.2	0.7	0.2	0.8	-0.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.2	-0.5	-0.5	-0.4
Leg predicted mass (left)	0.2	1.2	3.3	0.2	1.8	0.4
Mouth/teeth dental problems	0.2	0.2	0.6	0.2	0.8	0.2
Weight	0.2	0.8	1.3	0.7	1.1	0.8
Alcohol intake versus 10 years previously	0.2	0.2	0.5	0.5	0.2	0.7
Number of live births	0.2	0.2	0.4	0.6	0.5	0.4
Illnesses of mother	0.2	0.3	0.5	-0.7	-0.4	-0.4
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.5	0.2	0.5	-0.7
Comparative body size at age 10	0.2	0.7	1.8	-1.3	0.1	-0.5
Worry too long after embarrassment	0.2	0.4	0.8	-0.3	0.9	0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	0.8	0.9	0.4	0.3
Angina (self-reported)	0.2	0.3	0.4	0.4	-0.5	-0.6
Medication: Omeprazole	0.2	0.3	0.4	-0.4	0.5	-0.6
Heart disease (mother)	0.2	0.3	0.5	0.4	0.7	0.4
Overall health rating	0.2	0.4	0.7	-0.5	-0.4	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.3	0.6	-0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	-0.2	-0.6	-0.5
Illnesses of siblings: Diabetes	0.2	0.3	0.7	-0.5	-0.8	-0.0
Leg fat-free mass (right)	0.2	1.1	3.2	-0.2	1.8	0.4
Mineral and other dietary supplements	0.2	0.3	0.5	-0.5	0.0	-0.7
Leg predicted mass (right)	0.2	1.0	3.0	-0.2	1.7	0.3
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.3	-0.4	-0.5	-0.5
Ever smoked	0.2	0.3	0.5	-0.7	-0.4	-0.5
Age started oral contraceptive pill	0.2	0.2	0.4	-0.3	-0.2	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.4	0.2	0.7	-0.2
Basal cell carcinoma (self-reported)	0.2	0.2	0.7	-0.8	0.1	0.2
Heart disease (siblings)	0.2	0.2	0.5	0.1	-0.4	-0.7
Reaction Time	0.1	0.1	0.2	0.4	0.4	-0.3
Bipolar Disorder (2011)	0.1	0.1	0.3	-0.5	-0.1	-0.2
Heel T-Score	0.1	1.0	1.5	-0.7	-1.0	-1.2
BMI	0.1	0.7	1.0	0.5	1.0	0.9
Allergy or Eczema	0.1	0.2	0.5	-0.5	0.7	0.2
Respiratory disease	0.1	0.3	0.6	-0.6	0.8	0.1
Hair Pigment	0.1	2.0	3.5	-0.4	-1.5	-1.9
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.5	-0.3	0.0	-0.7
Diabetes (mother)	0.1	0.2	0.2	0.3	0.4	-0.4
Trunk fat percentage	0.1	0.3	0.7	0.1	-0.8	-0.3
Average weekly fortified wine intake	0.1	0.1	0.1	-0.2	0.4	-0.4
Relative age voice broke	0.1	0.1	0.1	-0.4	0.2	0.2
Taking other prescription medications	0.1	0.1	0.2	-0.4	0.2	0.2
Multivitamins +/- minerals	0.1	0.1	0.4	-0.2	-0.1	0.6
Medication: Levothyroxine sodium	0.1	0.2	0.5	-0.2	0.1	-0.7
Sitting height	0.1	0.9	1.5	1.2	0.0	1.2
Body mass index (BMI)	0.1	0.5	1.3	0.3	1.1	0.2
Alcohol usually taken with meals	0.1	0.1	0.2	-0.3	0.4	0.2
Time employed in main current job	0.1	0.1	0.2	0.3	-0.4	0.0
Pulse rate	0.1	0.2	0.4	-0.1	-0.6	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.3	0.3	-0.6	0.3	-0.6
Standing height	0.1	0.8	2.1	0.6	-0.1	1.5
Hair/balding pattern: Pattern 4	0.1	0.2	0.4	0.6	0.2	0.4
Blood clot in the leg (DVT)	0.1	0.2	0.3	-0.6	-0.4	-0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.5	-0.1	-0.7	-0.6
Birth weight	0.1	0.3	0.7	0.3	-0.8	-0.3
Mean time to correctly identify matches	0.1	0.2	0.6	-0.1	0.1	-0.8
Age at last live birth	0.1	0.1	0.3	-0.2	0.5	-0.3
Medication: Aspirin	0.1	0.1	0.1	0.3	-0.3	-0.2
Average weekly red wine intake	0.1	0.2	0.3	0.0	0.6	0.6
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	0.1	0.2	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.1	-0.3	0.0	-0.3
Commuting to job workplace: Walk	0.1	0.1	0.3	-0.2	0.0	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.3	-0.3	-0.3	0.6
Medication: Aspirin	0.1	0.1	0.2	0.2	-0.2	-0.4
Number of self-reported non-cancer illnesses	0.1	0.1	0.4	-0.2	0.6	-0.1
Guilty feelings	0.1	0.1	0.2	-0.4	0.4	-0.3
Mother’s age at death	0.1	0.1	0.2	-0.2	0.3	0.4
Financial situation satisfaction	0.1	0.1	0.3	0.2	0.6	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	0.3	-0.3	-0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.3	0.3	0.2	0.6
Medication: Lisinopril	0.1	0.2	0.3	0.5	-0.2	0.5
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	-0.2	0.5	0.0
Commuting to job workplace: Cycle	0.1	0.1	0.1	0.3	-0.2	-0.2
Height	0.0	0.4	0.8	0.3	0.9	0.6
Smoking Status	0.0	0.0	0.1	0.3	-0.1	0.0
Tanning	0.0	0.1	0.1	0.3	0.4	0.3
Ever used hormone-replacement therapy (HRT)	0.0	0.1	0.1	0.2	0.3	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	-0.2	-0.0	0.1
Trunk fat mass	0.0	0.0	0.1	0.2	-0.3	-0.0
Waist circumference	0.0	0.1	0.2	-0.2	0.4	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	-0.1	-0.3	-0.1
Arm fat percentage (right)	0.0	0.0	0.0	0.1	-0.2	-0.2
Medication: Lansoprazole	0.0	0.0	0.1	0.0	0.1	0.3
Arm fat mass (right)	0.0	0.1	0.2	0.3	0.5	0.3
Headache pain in last month	0.0	0.1	0.1	-0.4	0.2	0.3
Body fat percentage	0.0	0.2	0.4	0.1	-0.7	-0.2
Leg fat percentage (right)	0.0	0.2	0.2	0.5	-0.4	-0.2
Eye problems/disorders: None of the above	0.0	0.0	0.1	0.0	-0.3	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.1	0.1	-0.3	-0.2	0.2
Whole body fat mass	0.0	0.1	0.1	0.3	0.2	0.3
Leg fat mass (right)	0.0	0.2	0.3	0.5	0.4	0.2
Number of full sisters	0.0	0.0	0.1	0.0	-0.3	0.1
Illnesses of father: Heart disease	0.0	0.1	0.1	-0.2	-0.2	-0.3
Arm fat percentage (left)	0.0	0.1	0.2	-0.2	-0.2	-0.4
Qualifications: nursing, teaching	0.0	0.1	0.1	-0.1	0.3	-0.2
Arm fat mass (left)	0.0	0.1	0.1	0.2	0.3	0.3
Commuting to job workplace: Public transport	0.0	0.1	0.1	-0.1	-0.3	0.2
Leg fat percentage (left)	0.0	0.1	0.1	0.2	-0.4	-0.0
Pain experienced in last month	0.0	0.1	0.1	0.2	-0.4	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.1	-0.2	-0.1	-0.1
Leg fat mass (left)	0.0	0.1	0.1	0.3	0.3	0.3

Hub : Genes

SH3TC2

Models

Trait associations