[Hub]/) : Traits : Heel T-Score : ← →

chr9:34,992,074-36,556,091

Best TWAS P=3.8e-11 · Best GWAS P=3.53e-11 conditioned to 0.109

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	TPM2	0.29	0.22	lasso	5	0.25	1.8e-09	-6.2	5.5	3.4e-08	-0.90	0.08	0.92	FALSE
2	GTEx	Artery Aorta	SPAG8	0.11	0.10	lasso	7	0.06	2.0e-04	-5.9	5.8	6.3e-09	-0.69	0.07	0.91	FALSE
3	GTEx	Brain Cerebellar Hemisphere	TPM2	0.56	0.55	lasso	3	0.56	2.7e-17	-6.2	6.2	5.0e-10	-0.94	0.11	0.89	FALSE
4	GTEx	Brain Cerebellum	TPM2	0.63	0.43	lasso	4	0.53	4.0e-18	-6.2	6.4	1.6e-10	-0.97	0.04	0.96	FALSE
5	GTEx	Brain Hippocampus	TMEM8B	0.27	0.14	enet	15	0.14	4.4e-04	-6.2	6.2	5.2e-10	-0.83	0.04	0.72	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	TPM2	0.29	0.30	lasso	8	0.29	2.0e-08	-6.2	5.6	2.5e-08	-0.89	0.11	0.87	FALSE
7	GTEx	Breast Mammary Tissue (Female)	OR13E1P	0.06	0.05	lasso	2	0.01	1.4e-01	-5.5	5.5	3.8e-08	-0.65	0.04	0.28	FALSE
8	GTEx	Liver	NPR2	0.18	0.04	lasso	3	0.02	1.1e-01	-6.2	6.2	6.7e-10	-0.68	0.04	0.75	FALSE
9	GTEx	Muscle Skeletal	TPM2	0.06	0.02	lasso	5	0.02	6.2e-03	-6.6	-6.6	3.8e-11	0.89	0.02	0.95	TRUE
10	GTEx	Pancreas	TPM2	0.11	0.15	lasso	2	0.14	1.8e-06	-6.2	6.2	5.5e-10	-0.92	0.05	0.90	FALSE
11	GTEx	Thyroid	RP11-112J3.16	0.26	0.13	lasso	7	0.13	1.9e-10	-6.6	5.8	8.3e-09	-0.65	0.01	0.99	FALSE
12	METSIM	Adipose	TPM2	0.12	0.13	lasso	5	0.14	1.1e-19	-6.2	5.8	8.4e-09	-0.90	0.13	0.87	FALSE
13	NTR	Blood	TPM2	0.04	0.04	lasso	4	0.04	2.3e-13	-6.0	5.9	3.0e-09	-0.86	0.12	0.88	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	TPM2	0.55	0.60	enet	21	0.61	1.1e-100	-6.3	6.1	1.2e-09	-0.91	0.11	0.89	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	RP11-112J3.16	0.11	0.12	bslmm	410	0.11	1.5e-13	-6.6	6.0	1.9e-09	-0.67	0.01	0.99	FALSE
16	YFS	Blood	TPM2	0.46	0.50	enet	22	0.50	1.1e-194	-6.2	5.7	1.0e-08	-0.86	0.13	0.87	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	C9orf128	0.14	0.15	blup	50	0.16	1.4e-32	-5.6	6.3	2.5e-10	-0.69	0.24	0.76	FALSE
18	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GBA2	0.07	0.03	blup	44	0.03	1.1e-02	3.0	5.9	3.4e-09	-0.63	0.01	0.61	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	C9orf128	0.07	0.03	blup	50	0.06	2.3e-04	-5.5	5.5	3.6e-08	-0.66	0.01	0.93	FALSE
20	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TPM2	0.11	0.08	enet	6	0.11	1.0e-06	-5.8	5.8	7.0e-09	-0.78	0.04	0.94	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	TPM2	0.11	0.16	lasso	5	0.17	3.5e-19	-6.0	5.6	2.4e-08	-0.91	0.04	0.96	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	C9orf128	0.07	0.07	lasso	2	0.07	1.6e-08	-5.6	5.2	1.7e-07	-0.61	0.06	0.94	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C9orf128	0.02	0.01	blup	50	0.01	2.3e-02	-5.4	5.7	1.4e-08	-0.65	0.04	0.74	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	C9orf128	0.11	0.18	lasso	2	0.16	3.7e-16	-5.4	5.5	5.1e-08	-0.64	0.04	0.96	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM8B	0.04	0.02	blup	58	0.05	1.5e-05	-6.6	-5.3	1.1e-07	0.53	0.01	0.98	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	C9orf128	0.04	0.06	lasso	2	0.05	2.8e-04	-6.1	6.1	1.2e-09	-0.65	0.03	0.70	FALSE
27	The Cancer Genome Atlas	Stomach Adenocarcinoma	GBA2	0.04	0.03	blup	44	0.02	1.0e-02	3.3	5.4	8.5e-08	-0.54	0.06	0.22	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	C9orf128	0.12	0.19	lasso	1	0.20	8.5e-19	-5.4	5.4	5.2e-08	-0.64	0.45	0.55	FALSE
29	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SPAG8	0.18	0.07	blup	47	0.09	1.7e-03	-5.7	5.4	7.7e-08	-0.55	0.02	0.20	FALSE