Hub : Genes

GBA2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1500	0.0510	4.4e-04	0.103	NA	0.067	NA	0.071	2.8e-06	NA	1.5e-04	NA	9.8e-05
2	GTEx	Colon Transverse	0.1120	0.0490	9.1e-03	0.153	NA	0.149	NA	0.151	9.9e-08	NA	1.4e-07	NA	1.2e-07
3	GTEx	Esophagus Mucosa	0.1030	0.0350	4.2e-04	0.114	NA	0.071	NA	0.131	5.0e-08	NA	1.6e-05	NA	4.5e-09
4	GTEx	Heart Atrial Appendage	0.1180	0.0460	3.1e-03	0.130	NA	0.135	NA	0.129	2.0e-06	NA	1.2e-06	NA	2.2e-06
5	GTEx	Heart Left Ventricle	0.2893	0.0608	2.8e-09	0.219	NA	0.174	NA	0.183	6.4e-12	NA	1.4e-09	NA	5.2e-10
6	GTEx	Muscle Skeletal	0.1548	0.0394	2.6e-07	0.109	NA	0.060	NA	0.084	7.3e-11	NA	1.6e-06	NA	1.4e-08
7	GTEx	Nerve Tibial	0.1137	0.0404	2.6e-04	0.108	NA	0.056	NA	0.094	4.9e-08	NA	7.7e-05	NA	3.4e-07
8	GTEx	Whole Blood	0.0980	0.0350	3.4e-04	0.070	NA	0.040	NA	0.045	4.9e-07	NA	1.3e-04	NA	5.4e-05
9	METSIM	Adipose	0.0409	0.0178	3.0e-03	0.031	0.021	0.017	0.02	0.021	1.5e-05	3.2e-04	1.2e-03	0.00041	3.3e-04
10	TCGA	Cervical Squamous Cell Carcinoma	0.0730	0.0420	3.4e-03	0.028	0.031	0.013	NA	0.018	1.6e-02	1.1e-02	7.0e-02	NA	4.1e-02
11	TCGA	Colon Adenocarcinoma	0.0990	0.0610	8.7e-04	0.039	0.058	0.067	NA	0.043	2.7e-03	2.7e-04	1.0e-04	NA	1.7e-03
12	TCGA	Esophageal Carcinoma	0.1090	0.0670	6.1e-03	0.102	0.046	0.013	NA	0.078	4.0e-04	1.4e-02	1.3e-01	NA	1.8e-03
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0511	0.0247	4.4e-06	0.055	0.048	0.040	NA	0.044	8.5e-07	3.7e-06	2.4e-05	NA	1.0e-05
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0690	0.0400	2.4e-03	0.080	0.042	0.045	NA	0.072	2.4e-05	1.9e-03	1.4e-03	NA	6.4e-05
15	TCGA	Stomach Adenocarcinoma	0.0400	0.0230	4.6e-03	0.031	0.022	0.011	NA	0.017	2.4e-03	9.9e-03	4.9e-02	NA	1.9e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	2.2	3.5	7.9	-1.9	1.7	1.2	1.7	2.0	1.5	-1.7	1.8	-0.1	2.3	2.1	1.7	2.8	1.6	2.3
Bipolar Disorder or Schizophrenia	0.6	1.4	3.7	-1.1	0.9	0.2	1.0	1.2	0.7	-0.9	0.8	1.0	1.8	1.7	0.7	1.9	0.8	1.5
Depressed Affect (Nagel 2018)	0.2	0.4	0.8	-0.8	0.5	0.5	0.7	0.6	0.4	-0.6	0.6	-0.3	0.9	0.3	0.5	0.9	0.6	0.8
Depression (Nagel 2018)	2.7	4.1	6.9	-2.4	1.9	1.3	2.1	2.1	2.0	-2.1	2.2	0.6	2.4	1.5	2.0	2.6	2.1	2.3
Intelligence (Savage-Jansen 2018)	0.8	2.6	14.1	0.9	-1.5	-2.5	-1.3	-0.9	-1.1	1.0	-1.4	-3.8	0.7	-1.8	-1.4	-1.1	-1.1	0.2
Neuroticism (Nagel 2018)	0.5	1.3	3.4	-0.9	0.8	0.2	1.0	0.8	0.7	-0.9	1.0	-1.5	1.8	0.8	1.0	1.6	0.9	1.6
Schizophrenia (2018)	0.1	0.2	1.8	0.1	-0.2	-0.8	-0.1	-0.1	-0.3	0.2	-0.5	1.3	0.5	0.5	-0.5	0.2	-0.3	0.1
Schizophrenia vs Biploar Disorder	0.7	0.9	2.2	0.9	-0.9	-0.2	-0.8	-0.5	-0.7	0.9	-0.8	0.5	-1.3	-1.5	-0.7	-1.5	-0.8	-1.2
Worry (Nagel 2018)	0.7	1.6	3.7	-1.2	1.0	0.2	1.2	0.6	0.9	-1.2	1.2	-1.8	1.9	0.6	1.3	1.4	1.2	1.7
Alzheimer’s Disease (in mother)	3.4	4.0	6.5	-2.3	1.9	1.7	2.0	1.7	1.9	-2.0	2.1	0.5	2.4	2.1	2.0	2.5	2.0	2.2
Alzheimer’s Disease (in father)	2.7	2.9	4.2	1.6	-1.6	-1.5	-1.7	-1.4	-1.8	1.8	-1.8	-1.1	-2.0	-1.5	-1.7	-2.0	-1.8	-2.1
Alzheimer’s Disease (including proxy)	1.0	1.5	2.6	-1.6	1.3	1.0	1.3	1.2	1.3	-1.2	1.3	0.2	1.3	1.1	1.3	1.2	1.2	1.1
Crohns Disease (2017)	2.1	4.7	7.7	2.3	-2.4	-1.2	-2.2	-1.6	-2.2	2.3	-2.1	0.1	-2.6	-2.8	-2.5	-2.1	-2.2	-2.4
Irritable Bowel Disease (IBD)	1.2	2.8	4.0	1.7	-1.8	-1.1	-1.7	-1.6	-1.8	1.8	-1.7	-0.1	-1.9	-2.0	-1.9	-1.6	-1.6	-1.8
Ulcerative Colitis (UC)	0.5	1.0	1.4	0.9	-1.0	-0.8	-1.0	-1.2	-1.0	1.0	-1.0	-0.3	-1.1	-1.0	-1.0	-1.1	-0.8	-1.1
Major Depression (MDD)	1.2	1.4	2.1	1.4	-1.4	-1.0	-1.2	-0.6	-1.4	1.3	-1.2	-0.2	-1.2	-1.4	-1.2	-0.8	-1.4	-1.4
Reaction Time	0.6	1.2	2.3	1.1	-1.2	-0.6	-1.2	-0.6	-1.0	1.2	-0.9	-1.5	-1.3	-1.2	-1.1	-0.7	-1.1	-1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	5.8	-0.2	-0.3	-1.3	-0.1	0.2	-0.1	0.1	-0.2	-2.4	1.8	-0.3	-0.2	0.1	-0.1	1.3
Breast Cancer	0.6	1.5	2.2	1.5	-1.2	-1.0	-1.4	-1.2	-1.3	1.3	-1.2	-0.9	-1.5	-0.7	-1.3	-0.8	-1.4	-1.4
Ovarian Cancer	0.6	0.7	1.6	0.8	-0.8	-0.6	-0.8	-0.9	-0.9	1.0	-1.0	0.6	-1.0	0.0	-0.9	-0.8	-1.0	-1.2
Prostate Cancer	0.5	0.7	1.6	0.5	-1.0	-0.4	-1.0	-0.6	-0.9	0.9	-0.8	-0.5	-1.0	-1.3	-0.9	-0.9	-0.9	-0.7
Age at First Birth	2.0	3.0	5.6	-1.6	1.6	1.3	1.6	1.8	1.5	-1.7	1.8	-0.7	2.1	1.8	1.7	2.4	1.5	2.2
Bipolar Disorder (2011)	0.4	0.4	1.0	0.4	-0.7	-1.0	-0.7	-0.7	-0.8	0.6	-0.6	-0.2	0.1	0.5	-0.6	0.7	-0.8	-0.3
Body Mass Index (BMI) (2010)	1.7	2.4	5.6	1.4	-1.4	-0.8	-1.5	-1.1	-1.5	1.5	-1.7	-0.2	-2.4	-1.2	-1.6	-2.0	-1.5	-2.1
Coronary Artery Disease (CAD)	2.7	3.3	4.4	-2.1	1.7	1.4	2.0	2.1	2.0	-1.9	1.9	1.6	1.9	1.1	2.1	1.6	1.9	1.7
Crohns Disease (2012)	1.8	3.0	4.3	1.5	-1.8	-1.3	-1.8	-1.4	-1.8	1.8	-1.7	-1.0	-2.1	-1.9	-2.1	-1.5	-1.7	-2.0
Mean Putamen Volume	0.1	0.1	0.6	0.2	-0.1	0.6	0.0	-0.1	-0.1	0.0	-0.0	0.7	-0.7	-0.4	-0.1	-0.5	0.0	-0.6
Fasting Glucose	1.8	2.2	3.6	1.4	-1.4	-1.2	-1.5	-1.7	-1.4	1.4	-1.6	-1.0	-1.7	-1.2	-1.2	-1.9	-1.4	-1.9
HbA1C	2.9	3.2	6.0	-1.5	1.8	1.1	1.6	1.8	1.7	-1.7	1.8	1.1	2.0	2.3	1.8	2.4	1.7	1.8
HDL Cholesterol	0.1	0.2	1.4	0.4	-0.4	-0.3	-0.4	-0.3	-0.4	0.4	-0.2	-1.2	-0.0	-0.4	-0.4	0.4	-0.3	-0.1
LDL Cholesterol	0.4	0.6	1.7	-0.7	0.5	0.6	0.7	0.9	0.6	-0.6	0.5	1.3	0.9	-0.7	0.5	-0.2	0.6	1.1
Lupus	2.3	3.5	6.0	-1.8	1.9	1.8	2.0	2.0	2.0	-2.1	2.0	1.0	2.1	0.8	1.9	1.4	2.0	2.4
Neuroticism (2016)	0.2	0.4	1.4	-0.2	0.3	-0.1	0.4	0.4	0.3	-0.3	0.4	-0.2	1.1	0.8	0.6	1.2	0.2	0.9
Primary Biliary Cirrhosis	0.4	0.5	3.5	-0.2	-0.4	-0.6	-0.3	-0.1	-0.2	0.2	-0.3	-1.9	0.3	-1.6	-0.3	-0.9	-0.2	0.3
Rheumatoid Arthritis	0.2	0.3	1.7	-0.5	0.5	0.5	0.4	0.4	0.5	-0.5	0.4	-1.3	-0.1	0.1	0.4	0.2	0.5	0.2
Schizophrenia (2014)	0.1	0.3	1.9	-0.3	0.1	-0.3	0.2	0.4	-0.0	-0.2	-0.0	1.4	0.7	0.5	-0.1	0.6	-0.0	0.5
Triglycerides	1.9	3.1	9.7	-2.1	1.9	2.2	1.9	1.3	1.8	-1.8	1.6	3.1	0.6	1.0	1.9	-0.1	1.7	1.3
Type 2 Diabetes (T2D) (2012)	4.1	4.7	8.3	2.0	-1.9	-1.8	-2.3	-2.9	-2.2	2.2	-2.4	-0.8	-2.3	-1.5	-2.8	-2.2	-2.1	-2.4
Ulcerative Colitis	0.6	0.8	1.7	0.8	-0.9	-0.9	-1.0	-1.0	-1.0	0.8	-0.8	-0.8	-0.8	-1.3	-1.0	-0.9	-0.8	-0.8
Blood Eosinophil Count	1.7	13.0	18.7	3.9	-3.6	-3.1	-3.6	-3.8	-3.7	3.7	-4.0	-0.8	-3.7	-3.1	-3.8	-4.3	-3.7	-3.9
Blood Platelet Count	5.0	57.4	87.6	7.6	-7.4	-6.5	-7.5	-7.7	-7.5	7.7	-8.4	-2.9	-8.5	-6.1	-7.6	-9.4	-7.8	-8.9
Blood Red Count	0.5	4.7	12.7	-2.4	2.4	3.6	2.2	2.4	2.5	-2.3	2.4	1.2	0.2	1.9	2.4	1.3	2.3	0.9
Blood White Count	3.9	29.1	58.5	5.3	-4.8	-3.1	-5.0	-4.9	-5.1	5.3	-5.6	-2.2	-7.7	-4.5	-5.2	-7.2	-5.3	-7.2
Heel T-Score	1.5	11.9	34.9	-3.5	2.7	1.4	3.1	3.2	3.2	-3.3	3.5	-0.8	5.9	1.6	3.4	3.9	3.2	5.4
BMI	2.9	16.8	24.2	4.7	-4.1	-2.7	-4.2	-3.6	-4.4	4.4	-4.4	-1.3	-4.9	-3.1	-4.5	-4.2	-4.4	-4.9
Height	0.3	6.6	22.6	-0.5	1.9	4.2	1.2	1.2	1.1	-1.0	1.8	4.5	-2.0	4.8	0.8	4.5	1.0	-0.5
Waist Hip Ratio (WHR)	0.8	3.7	13.2	-2.1	1.5	0.2	1.8	1.0	1.7	-1.8	1.6	1.6	3.6	1.1	1.7	1.6	1.8	3.2
Systolic Blood Pressure	0.1	0.7	2.6	0.8	-0.6	-0.6	-0.7	-1.2	-0.7	0.5	-0.1	-1.6	0.8	-0.1	-0.5	1.5	-0.5	0.3
Smoking Status	3.0	7.2	10.4	-3.2	2.9	2.8	2.9	3.0	3.0	-3.0	3.1	1.0	2.0	1.5	3.1	2.0	3.1	2.4
Allergy or Eczema	0.2	0.4	1.0	-0.5	0.5	0.8	0.5	0.4	0.5	-0.5	0.6	1.0	0.9	0.7	0.6	0.8	0.6	0.9
Cardiovascular Disease	0.6	1.9	8.5	1.0	-1.5	-1.5	-1.3	-1.8	-1.4	1.3	-1.1	-2.9	0.5	-0.9	-1.5	0.3	-1.3	-0.1
Hypothyroidism (self reported)	0.2	0.4	1.1	0.4	-0.6	-0.1	-0.6	-0.2	-0.6	0.7	-0.6	0.5	-1.1	-0.5	-0.6	-0.8	-0.6	-0.9
Respiratory disease	0.2	0.4	2.3	-0.5	0.3	1.1	0.1	0.3	0.2	-0.2	0.4	1.5	-0.1	0.9	0.2	1.0	0.2	-0.1
Type 2 Diabetes (T2D) (2018)	3.0	5.6	8.2	2.5	-2.4	-1.3	-2.4	-2.2	-2.4	2.5	-2.5	-0.1	-2.9	-2.4	-2.4	-2.8	-2.5	-2.7
Lung FEV1/FVC ratio	3.4	17.4	21.9	-4.6	4.6	3.4	4.4	3.9	4.4	-4.7	4.4	2.9	4.2	3.7	4.3	3.5	4.7	4.4
Lung FVC	0.1	0.6	1.6	1.2	-0.8	-1.1	-0.8	-0.5	-0.8	0.9	-0.8	-0.8	-0.4	-0.1	-0.6	-0.4	-0.9	-0.6
Neuroticism	0.6	1.4	3.2	-1.2	0.9	0.2	1.1	0.9	0.9	-1.1	1.1	-1.8	1.8	0.5	1.2	1.4	1.1	1.6
Chronotype (morning person)	1.7	3.9	7.6	-2.1	2.3	2.7	2.1	1.9	2.1	-2.1	1.9	2.8	0.2	1.9	2.0	0.7	2.1	0.8
Hair Pigment	0.0	0.9	1.7	-1.0	1.0	0.3	1.3	0.6	1.3	-1.1	0.9	0.2	1.1	0.0	1.3	-0.2	1.2	1.1
Tanning	0.2	2.6	3.7	-1.9	1.8	1.6	1.8	1.0	1.7	-1.9	1.8	0.3	1.6	1.0	1.9	1.1	1.9	1.8
Hand grip strength (left)	3.7	9.7	13.5	-2.9	3.0	2.9	3.1	3.3	3.0	-2.9	3.2	3.2	2.9	3.4	3.2	3.7	2.9	3.1
Number of treatments/medications taken	0.3	0.5	1.6	0.5	-0.7	-1.2	-0.8	-0.9	-0.7	0.7	-0.6	-0.7	0.4	0.1	-0.9	0.6	-0.6	-0.2
Average weekly spirits intake	0.4	0.5	1.9	0.5	-0.8	-0.8	-0.6	-0.7	-0.8	0.7	-0.7	-0.1	-0.1	-1.4	-0.6	-1.0	-0.8	-0.1
Sensitivity / hurt feelings	0.7	1.2	3.1	-0.3	0.9	0.1	1.0	0.7	0.9	-0.9	0.9	-0.5	1.7	1.5	1.0	1.8	0.9	1.4
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.5	-0.2	0.0	-0.5	0.5	0.4	0.3	-0.3	0.4	-0.8	1.6	-0.3	0.5	0.8	0.3	1.2
Hearing difficulty/problems: Yes	0.6	0.9	2.9	0.7	-0.7	-0.3	-1.0	-0.8	-1.0	0.8	-0.8	1.7	-1.3	-0.5	-1.2	-0.8	-0.9	-1.1
Relative age of first facial hair	0.2	0.4	3.2	-0.5	0.2	-0.5	0.4	0.5	0.4	-0.4	0.3	0.3	1.8	0.2	0.4	0.5	0.4	1.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.8	0.1	-0.0	0.2	-0.3	-0.3	-0.1	0.1	0.1	0.1	-0.3	0.4	-0.1	0.9	-0.0	-0.3
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.1	-0.2	0.1	-0.3	0.0	-0.2	0.1	-0.1	0.1	-0.1	-0.1	-0.1	-0.1	0.3	0.0	-0.1
Ever had hysterectomy (womb removed)	0.6	0.7	1.8	-0.5	0.9	0.0	0.6	0.6	0.9	-0.8	0.8	-0.1	0.9	1.2	0.7	1.3	0.9	0.8
Systolic blood pressure, automated reading	0.1	0.2	1.4	0.2	0.1	0.6	-0.2	-0.2	-0.1	-0.1	0.4	-0.5	0.2	0.0	-0.1	1.2	0.1	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.3	0.0	0.3	0.4	0.3	-0.1	0.2	-0.2	0.3	1.1	0.5	0.9	0.3	0.7	0.2	0.5
Angina	1.0	1.4	4.3	-1.0	0.9	0.4	1.1	0.9	0.9	-1.1	1.1	0.6	2.1	0.8	1.0	1.6	1.1	1.8
Medication for hormone replacement therapy	1.0	1.1	3.9	-0.9	1.0	0.9	0.7	1.1	0.9	-0.9	1.1	-0.6	0.6	1.8	0.9	2.0	0.9	0.5
Vitamin and mineral supplements	0.6	0.8	1.6	1.0	-1.1	-0.8	-0.9	-1.3	-0.9	1.0	-0.9	-0.1	-0.5	-1.3	-0.8	-0.7	-1.0	-0.6
Supplements: Zinc	0.4	0.5	1.7	0.7	-0.6	-1.3	-0.7	-0.6	-0.6	0.5	-0.6	-1.3	0.2	-0.5	-0.7	-0.2	-0.5	-0.2
Medication: Co-codamol	1.7	2.0	4.2	1.4	-1.3	-0.3	-1.4	-1.2	-1.4	1.4	-1.4	-0.3	-2.1	-1.1	-1.6	-1.6	-1.4	-1.8
Medication: Metformin	0.8	1.2	6.4	1.0	-0.4	0.3	-0.9	-0.7	-0.8	0.8	-0.8	0.9	-2.5	0.3	-0.7	-0.9	-0.8	-2.0
Diabetes (father)	1.3	1.6	2.5	1.6	-1.5	-1.5	-1.4	-0.9	-1.6	1.5	-1.5	0.4	-0.7	-1.1	-1.4	-1.0	-1.5	-0.9
Diabetes (mother)	5.3	6.7	9.7	2.6	-2.9	-2.8	-2.8	-2.7	-2.8	2.8	-3.0	-0.3	-2.0	-2.3	-3.1	-2.5	-2.7	-2.4
Severe depression (siblings)	1.6	1.8	3.3	-1.8	1.5	1.2	1.3	1.6	1.4	-1.4	1.5	-0.1	1.0	1.2	1.4	1.6	1.5	1.0
Pack years adult smoking proportion	3.5	5.4	8.4	-2.7	2.6	2.7	2.8	2.9	2.8	-2.6	2.5	0.5	1.1	1.1	2.7	1.1	2.7	1.7
Impedance of leg (right)	0.6	3.0	8.1	-2.1	1.7	0.1	1.6	1.1	1.9	-2.0	1.6	-0.1	2.8	0.0	1.8	0.7	1.9	2.8
Leg fat-free mass (left)	1.2	6.3	16.4	3.0	-2.2	0.1	-2.4	-2.2	-2.8	2.9	-2.2	1.2	-4.0	0.7	-2.7	0.1	-2.9	-3.6
Trunk fat percentage	3.0	11.8	16.6	4.1	-3.5	-2.5	-3.8	-3.6	-3.9	3.8	-3.7	-0.1	-3.7	-2.3	-4.1	-2.7	-3.8	-3.6
Hand grip strength (right)	3.3	9.0	12.2	-2.7	2.9	2.6	3.0	2.9	2.8	-2.8	3.0	3.1	3.1	3.3	3.1	3.5	2.8	3.2
Townsend deprivation index at recruitment	0.3	0.4	0.8	-0.7	0.6	0.3	0.8	0.7	0.6	-0.6	0.6	0.8	0.9	0.2	0.7	0.4	0.6	0.7
Current tobacco smoking	6.0	9.8	12.5	-3.4	3.5	3.1	3.4	3.4	3.4	-3.5	3.5	1.7	2.3	2.6	3.5	2.9	3.5	2.7
Average weekly fortified wine intake	0.6	0.6	2.1	0.6	-0.8	-1.5	-0.7	-1.0	-0.9	0.7	-0.9	-0.3	0.1	-0.7	-0.7	-1.2	-0.7	-0.3
Maternal smoking around birth	0.0	0.1	0.2	0.2	0.1	0.1	0.2	-0.4	-0.0	-0.1	0.0	0.4	-0.4	-0.4	0.1	-0.5	0.0	-0.3
Fed-up feelings	0.3	0.5	1.0	1.0	-0.9	-0.8	-0.6	-0.8	-1.0	0.8	-0.6	-0.8	0.1	-0.7	-0.7	0.1	-0.8	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	4.4	-1.4	1.6	1.3	1.8	1.8	1.7	-1.8	1.9	0.7	2.0	0.8	1.8	2.1	1.8	2.0
Relative age voice broke	1.5	2.2	4.1	1.3	-1.6	-2.0	-1.4	-1.6	-1.4	1.5	-1.6	-1.1	-0.7	-1.8	-1.4	-1.8	-1.5	-1.1
Taking other prescription medications	1.0	1.6	2.4	0.8	-1.3	-1.5	-1.4	-1.5	-1.4	1.4	-1.4	-0.2	-1.1	-1.0	-1.5	-1.0	-1.3	-1.2
Age when periods started (menarche)	1.0	2.4	3.2	1.6	-1.6	-1.8	-1.5	-1.4	-1.5	1.5	-1.6	-1.3	-1.1	-1.8	-1.8	-1.8	-1.5	-1.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.0	-0.2	0.4	0.4	0.3	0.5	0.4	-0.3	0.3	0.6	-0.1	1.0	0.5	0.5	0.2	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.3	12.0	-2.5	2.5	2.3	2.7	3.1	2.7	-2.7	2.8	0.8	3.5	2.3	2.7	2.9	2.6	3.5
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	3.9	2.0	-1.5	-1.4	-1.6	-1.4	-1.6	1.5	-1.3	0.1	-0.7	-0.5	-1.4	0.0	-1.6	-1.1
Qualifications: CSEs or equivalent	3.5	4.6	7.5	2.7	-2.2	-1.5	-2.2	-2.4	-2.6	2.5	-2.3	-0.5	-2.2	-0.4	-2.5	-0.9	-2.5	-2.5
Serious illness, injury or assault to yourself	0.2	0.2	1.5	-0.3	-0.1	-0.2	0.2	-0.7	-0.0	-0.2	0.2	-0.2	1.2	-0.6	0.2	0.1	0.1	1.0
High blood pressure	1.0	2.8	10.2	1.4	-1.8	-1.6	-1.7	-2.3	-1.7	1.6	-1.3	-3.2	-0.4	-1.5	-1.8	-0.2	-1.5	-0.8
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.0	-1.0	1.0	1.0	0.9	0.8	1.0	-1.0	1.1	0.3	1.5	1.7	1.0	1.7	1.0	1.3
Multivitamins +/- minerals	0.1	0.1	0.5	-0.0	0.3	-0.0	0.1	0.3	0.1	-0.2	0.1	0.6	0.1	0.7	0.1	0.3	0.2	-0.1
Stomach or abdominal pain in last month	3.4	4.2	5.4	1.8	-2.1	-1.9	-2.3	-2.2	-2.0	2.0	-2.2	-1.3	-2.2	-1.9	-2.3	-2.0	-2.0	-2.3
Supplements: Glucosamine	1.4	1.8	3.7	1.0	-1.3	-1.5	-1.4	-1.2	-1.3	1.2	-1.3	-1.9	-0.8	-1.7	-1.3	-1.5	-1.3	-0.9
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.3	0.2	-0.5	0.7	-0.5	-0.4	-0.7	0.7	-0.4	1.8	-1.6	-0.2	-0.5	-0.2	-0.6	-1.3
Medication: Atenolol	0.5	0.6	2.6	0.6	-0.8	-0.7	-0.9	-0.9	-0.6	0.6	-0.5	-1.6	-0.1	-0.9	-1.0	-0.2	-0.6	-0.3
Medication: Levothyroxine sodium	0.3	0.5	1.4	0.4	-0.5	-0.1	-0.5	-0.7	-0.6	0.6	-0.7	1.0	-1.2	-0.4	-0.5	-1.1	-0.6	-1.0
Sitting height	0.2	1.3	4.4	1.2	-0.3	1.1	-0.6	-0.7	-0.8	0.8	-0.1	1.1	-1.8	1.8	-0.7	2.1	-0.8	-1.3
Chronic bronchitis/emphysema (father)	1.2	1.4	2.0	1.3	-1.3	-1.0	-1.1	-1.1	-1.2	1.3	-1.3	-0.6	-1.2	-1.0	-1.4	-1.0	-1.3	-1.4
High blood pressure (mother)	0.1	0.2	0.8	-0.4	0.3	-0.0	0.2	-0.3	0.1	-0.3	0.3	-0.1	0.6	0.7	0.1	0.9	0.3	0.4
Body mass index (BMI)	2.5	10.5	14.6	3.7	-3.3	-2.0	-3.4	-3.1	-3.6	3.5	-3.4	-0.6	-3.8	-2.4	-3.6	-3.1	-3.5	-3.8
Impedance of leg (left)	1.2	5.8	13.9	-2.7	2.4	0.6	2.4	1.7	2.7	-2.8	2.4	0.8	3.7	0.6	2.6	1.2	2.8	3.7
Leg predicted mass (left)	1.1	5.9	16.0	3.0	-2.1	0.2	-2.4	-2.2	-2.7	2.8	-2.1	1.2	-4.0	0.7	-2.6	0.1	-2.8	-3.6
Trunk fat mass	3.2	13.7	19.6	4.4	-3.8	-2.3	-4.1	-3.9	-4.2	4.2	-3.9	0.2	-4.4	-2.0	-4.3	-2.5	-4.2	-4.2
Waist circumference	1.9	7.0	9.9	3.0	-2.7	-1.6	-2.8	-3.0	-3.0	3.0	-2.8	0.6	-3.1	-1.5	-3.1	-2.1	-2.9	-3.0
Number of incorrect matches in round	0.1	0.1	0.5	-0.2	0.2	0.5	0.1	0.1	0.0	-0.1	0.2	0.7	-0.5	0.1	-0.1	0.3	0.1	-0.4
Past tobacco smoking	0.2	0.3	1.6	0.4	0.0	0.3	-0.1	-0.2	-0.3	0.2	-0.3	1.3	-1.1	0.8	-0.5	-0.3	-0.2	-0.8
Alcohol usually taken with meals	5.8	9.4	11.8	3.2	-3.2	-3.3	-3.2	-3.4	-3.1	3.1	-3.2	-2.7	-2.5	-3.1	-3.0	-2.8	-3.1	-2.8
Nervous feelings	0.5	0.9	1.9	-0.8	0.8	0.3	0.9	0.7	0.8	-0.9	0.9	-1.1	1.4	0.5	1.0	1.2	1.0	1.3
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	4.6	-2.1	1.5	0.6	1.6	1.2	1.5	-1.7	1.5	-0.6	1.9	1.1	1.5	1.4	1.7	1.7
Hearing difficulty/problems with background noise	0.2	0.4	1.9	-0.4	0.3	-0.1	0.0	0.2	0.1	-0.2	0.4	1.2	0.6	1.1	0.1	1.4	0.3	0.4
Hair/balding pattern: Pattern 2	0.4	0.5	1.7	0.2	-0.5	-1.3	-0.5	-0.7	-0.5	0.3	-0.5	-0.8	1.0	-1.1	-0.5	-0.6	-0.3	0.7
Had menopause	0.7	0.9	2.8	0.4	-0.8	-0.5	-0.8	-1.0	-0.8	0.7	-0.7	-1.7	-1.1	-1.5	-0.8	-0.9	-0.7	-0.9
Had other major operations	0.2	0.2	0.9	-0.7	0.3	-0.5	0.2	-0.2	0.1	-0.4	0.2	-1.0	0.9	-0.2	0.3	0.0	0.3	0.7
Forced vital capacity (FVC)	0.2	0.9	4.1	-0.0	0.8	1.4	0.7	0.6	0.5	-0.4	0.7	1.4	-0.3	2.0	0.7	1.7	0.4	0.1
Heel bone mineral density (BMD) T-score, automated (right)	2.2	5.0	8.3	-2.1	2.2	1.9	2.2	2.3	2.3	-2.3	2.4	0.2	2.8	1.8	2.2	2.4	2.2	2.9
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.5	-0.7	0.1	-0.1	0.2	0.3	0.1	-0.2	0.2	0.5	0.6	-0.4	0.0	0.2	0.2	0.5
Qualifications: None of the above	1.7	3.6	9.9	-2.0	2.1	1.6	2.2	1.9	2.0	-1.9	1.7	3.1	1.2	1.8	1.9	1.0	1.9	1.4
Financial difficulties in last 2 years	0.2	0.3	0.7	0.8	-0.5	0.1	-0.6	0.0	-0.6	0.5	-0.3	-0.8	-0.8	-0.6	-0.8	0.1	-0.4	-0.5
Mouth/teeth dental problems	0.8	1.2	1.7	-1.1	1.1	0.7	1.1	1.3	1.2	-1.2	1.1	1.2	1.2	0.4	1.2	0.3	1.2	1.3
Heart attack	1.9	2.4	6.4	-1.3	1.4	0.6	1.5	1.5	1.6	-1.5	1.6	0.4	2.5	1.2	1.6	1.6	1.6	2.2
Allergy	0.1	0.2	1.0	0.1	-0.2	-0.8	-0.0	-0.1	-0.1	0.1	-0.3	-0.1	-0.1	-0.9	-0.2	-1.0	-0.1	-0.1
Pain all over the body in last month	2.0	2.1	4.0	-1.5	1.3	0.8	1.5	1.6	1.3	-1.3	1.4	0.2	1.9	1.6	1.2	2.0	1.3	1.7
Diabetes (self-reported)	1.0	1.6	5.5	1.0	-1.0	0.1	-1.1	-1.1	-1.2	1.2	-1.2	0.8	-2.3	-0.4	-1.2	-1.3	-1.2	-2.0
Hayfever/allergic rhinitis (self-reported)	4.6	6.1	9.1	-2.4	2.4	2.5	2.4	2.5	2.5	-2.4	2.7	0.4	2.7	2.4	2.4	3.0	2.5	2.8
Medication: Ramipril	0.5	0.7	2.9	-1.0	0.5	0.1	0.8	0.5	0.6	-0.7	0.7	-0.4	1.7	-0.0	0.7	0.4	0.8	1.5
Medication: Simvastatin	0.5	0.8	1.6	0.7	-0.9	-0.6	-1.1	-0.7	-1.1	0.9	-0.9	0.2	-1.0	-0.8	-1.3	-0.6	-1.0	-1.0
Fluid intelligence score	0.9	1.9	8.7	1.1	-1.3	-2.4	-1.1	-0.7	-1.0	1.2	-1.3	-3.0	0.9	-0.9	-1.2	-0.8	-1.1	0.2
Illnesses of siblings	0.6	0.8	1.3	-1.1	0.9	0.7	1.1	1.1	1.0	-0.9	0.9	-0.1	0.8	0.6	1.1	0.6	0.9	0.8
Neuroticism score	0.7	1.5	4.3	-0.8	1.0	0.3	1.1	0.8	0.9	-1.0	1.2	-1.1	1.9	1.2	1.2	2.1	1.1	1.6
Weight	2.0	9.7	20.0	3.8	-3.0	-1.0	-3.3	-3.2	-3.5	3.6	-3.1	0.9	-4.5	-1.0	-3.5	-1.5	-3.5	-4.1
Impedance of arm (right)	0.2	1.2	2.8	0.9	-1.0	-1.7	-1.2	-1.3	-1.0	1.0	-1.2	-1.1	-0.7	-1.0	-1.1	-1.0	-1.0	-0.6
Arm fat percentage (right)	5.5	21.8	27.4	5.1	-4.8	-3.4	-5.0	-4.7	-5.0	5.0	-5.0	-1.5	-5.2	-3.8	-5.2	-4.6	-5.0	-5.2
Trunk fat-free mass	0.4	2.6	9.1	1.7	-1.0	1.2	-1.2	-1.2	-1.5	1.6	-0.9	1.7	-3.0	1.4	-1.2	1.1	-1.5	-2.4
Hip circumference	3.8	16.4	32.8	4.6	-3.9	-1.9	-4.3	-4.0	-4.4	4.5	-4.1	-0.8	-5.7	-2.1	-4.5	-3.0	-4.5	-5.2
Time employed in main current job	0.1	0.2	0.7	0.6	0.1	-0.3	0.1	-0.2	0.1	-0.1	0.2	0.1	0.8	0.5	0.0	0.7	0.1	0.6
Alcohol intake versus 10 years previously	0.1	0.2	0.8	0.6	-0.3	-0.9	-0.3	-0.3	-0.3	0.3	-0.3	0.2	0.8	0.6	-0.2	0.3	-0.2	0.3
Father’s age at death	0.9	1.2	2.0	1.2	-1.2	-1.1	-1.2	-1.1	-1.2	1.1	-1.1	0.4	-0.9	-1.4	-1.2	-1.1	-1.1	-0.9
Worrier / anxious feelings	1.1	2.0	3.2	-1.3	1.5	0.5	1.5	1.0	1.4	-1.5	1.4	-1.5	1.8	1.4	1.6	1.4	1.5	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.6	-0.7	0.7	1.2	0.8	0.8	0.6	-0.6	0.7	1.1	0.1	1.1	0.6	1.0	0.6	0.3
Falls in the last year	0.9	1.2	1.8	-0.9	1.0	1.3	1.0	1.1	1.0	-1.2	1.3	1.4	0.7	0.1	1.2	1.0	1.2	1.2
Hair/balding pattern: Pattern 3	2.1	3.2	4.8	-2.2	1.7	1.6	2.0	1.8	1.8	-1.8	1.8	1.4	2.0	1.2	2.0	1.3	1.7	2.2
Number of live births	0.2	0.3	2.5	-0.3	0.4	0.7	0.5	0.5	0.6	-0.5	0.4	1.6	-0.2	-0.1	0.4	-0.3	0.5	0.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	5.4	-0.3	1.0	1.3	0.9	0.8	0.7	-0.7	1.0	1.5	0.4	2.3	0.9	2.2	0.7	0.6
Pulse rate	0.5	0.9	3.1	-0.3	0.6	-0.1	1.0	1.0	1.1	-0.8	0.7	-0.5	1.8	0.5	1.0	0.8	0.8	1.5
Happiness	0.8	0.9	1.7	-0.6	1.1	0.9	0.9	1.1	0.9	-1.0	1.0	1.1	0.4	1.3	0.8	1.3	1.0	0.4
Noisy workplace	0.1	0.2	0.4	-0.3	0.4	0.3	0.3	-0.0	0.4	-0.5	0.4	-0.4	0.6	0.5	0.2	0.2	0.4	0.6
Qualifications: A levels/AS levels or equivalent	2.1	4.6	12.0	1.9	-2.2	-2.4	-2.3	-2.3	-2.2	2.2	-2.1	-3.5	-1.4	-1.3	-2.2	-1.2	-2.1	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	3.0	0.5	-0.6	-1.7	-0.6	-0.8	-0.6	0.6	-0.7	-1.3	0.5	-0.2	-0.7	-0.4	-0.6	-0.1
Mouth/teeth dental problems: Dentures	0.4	0.7	4.2	0.1	0.3	1.2	0.0	-0.6	0.0	0.1	-0.1	1.2	-2.0	0.5	-0.2	-0.5	-0.0	-1.5
Asthma	0.4	0.8	3.0	-0.8	0.7	1.7	0.5	0.5	0.6	-0.5	0.7	0.7	-0.4	1.7	0.5	1.3	0.5	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.1	-0.9	0.9	0.6	0.8	0.3	0.7	-0.8	0.7	0.5	0.5	1.1	0.7	0.7	0.8	0.6
Medication: Cholesterol lowering	0.3	0.4	2.3	-0.3	0.3	0.9	0.1	0.7	0.1	-0.2	0.4	1.5	0.1	1.1	-0.2	1.2	0.2	0.0
Depression (self-reported)	1.1	1.4	3.5	-1.4	1.0	0.4	1.1	0.3	0.9	-1.2	1.2	-0.1	1.8	0.8	0.9	1.9	1.3	1.5
Medication: Lansoprazole	0.1	0.1	0.3	-0.3	0.3	0.2	0.1	0.2	0.3	-0.3	0.2	0.5	-0.1	0.3	0.1	-0.2	0.2	-0.0
Prospective memory result	0.3	0.4	1.0	-1.0	0.6	0.8	0.6	0.4	0.5	-0.6	0.7	-0.2	0.4	0.3	0.5	0.6	0.6	0.6
Lung cancer (father)	0.1	0.2	1.2	0.2	0.2	0.4	0.3	0.6	0.3	-0.2	0.3	1.1	-0.1	0.2	0.4	0.2	0.2	0.1
Illnesses of mother	0.3	0.4	1.7	-0.4	0.7	0.8	0.6	1.3	0.8	-0.6	0.5	0.6	-0.2	0.6	0.9	-0.2	0.6	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.5	-0.2	0.8	1.2	0.8	0.8	0.6	-0.6	0.8	1.6	0.3	1.5	0.9	1.4	0.5	0.6
Pulse wave Arterial Stiffness index	0.4	0.5	1.0	0.3	-0.8	-0.4	-0.7	-1.0	-0.8	0.7	-0.6	0.4	-0.9	-1.0	-0.8	-0.3	-0.7	-0.8
Impedance of arm (left)	0.1	0.2	1.6	0.4	-0.3	-1.2	-0.5	-0.5	-0.3	0.3	-0.5	-0.6	0.2	-0.2	-0.4	-0.1	-0.4	0.2
Arm fat mass (right)	3.6	14.9	24.0	4.4	-3.9	-2.1	-4.2	-3.9	-4.3	4.3	-4.0	-0.3	-4.9	-2.4	-4.4	-3.1	-4.3	-4.7
Trunk predicted mass	0.5	2.6	9.3	1.7	-1.0	1.1	-1.2	-1.3	-1.6	1.6	-1.0	1.6	-3.0	1.4	-1.3	1.1	-1.6	-2.5
Standing height	0.3	2.9	11.7	0.4	0.5	2.3	0.2	-0.2	-0.1	0.2	0.6	3.4	-1.7	3.3	0.1	3.4	-0.2	-0.7
Length of working week for main job	0.1	0.1	0.4	0.1	-0.2	-0.2	-0.3	-0.7	-0.5	0.3	-0.3	-0.2	-0.5	0.1	-0.3	-0.0	-0.3	-0.6
Exposure to tobacco smoke at home	1.3	1.4	2.5	0.9	-1.2	-1.2	-1.1	-1.3	-1.1	1.1	-1.2	-1.3	-0.9	-1.5	-1.2	-1.6	-1.1	-1.1
Breastfed as a baby	3.5	4.3	5.7	2.3	-2.1	-1.8	-2.4	-2.2	-2.3	2.2	-2.1	-1.7	-2.1	-1.4	-2.4	-1.1	-2.2	-2.4
Tense / ‘highly strung’	3.1	5.1	10.4	-2.2	2.3	2.0	2.3	2.1	2.2	-2.2	2.4	0.5	2.1	2.9	2.2	3.2	2.2	2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.4	-0.8	-1.1	-0.4	-1.2	-0.8	0.6	-0.7	-0.6	0.5	-0.2	-0.7	0.1	-0.6	-0.1
Hair/balding pattern: Pattern 4	0.1	0.2	1.0	1.0	-0.3	-0.7	-0.3	-0.1	-0.3	0.3	-0.1	-0.3	0.6	-0.1	-0.2	0.9	-0.2	0.4
Birth weight of first child	0.7	1.2	3.4	-0.9	0.9	1.7	0.8	1.0	0.9	-0.7	1.0	1.8	0.1	1.5	0.8	1.6	0.7	0.5
Peak expiratory flow (PEF)	1.6	3.6	6.9	-2.0	1.7	1.5	1.8	1.6	1.7	-1.7	2.0	1.4	2.2	2.0	1.9	2.6	1.7	2.3
Pulse wave reflection index	0.5	0.6	1.9	0.3	-0.7	-0.3	-0.8	-0.5	-0.9	0.7	-0.7	0.3	-1.4	-1.0	-0.8	-0.8	-0.8	-1.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.6	-0.7	0.7	0.4	0.6	0.7	0.5	-0.7	0.8	0.3	1.0	1.1	0.7	1.6	0.6	0.9
Loud music exposure frequency	0.6	0.7	2.6	-0.6	0.9	0.7	0.7	0.9	0.8	-1.0	1.1	-0.2	0.4	0.5	0.6	1.6	1.0	0.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.4	0.9	-1.0	-1.2	-1.2	-1.1	-1.0	0.9	-0.8	-1.2	-0.3	-0.6	-0.8	-0.1	-0.9	-0.5
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.3	0.7	-0.8	-1.0	-0.6	-0.2	-0.6	0.6	-0.5	-1.5	0.2	-1.2	-0.6	-0.1	-0.7	0.1
Blood clot in the leg (DVT)	0.2	0.2	0.7	0.4	-0.5	-0.5	-0.4	-0.9	-0.6	0.5	-0.6	-0.6	-0.0	-0.2	-0.5	-0.3	-0.6	-0.2
Medication: Paracetamol	0.1	0.1	0.4	0.3	-0.2	-0.3	-0.3	-0.4	-0.2	0.2	-0.3	0.6	-0.1	-0.2	-0.4	-0.2	-0.3	-0.2
Headache pain in last month	6.8	11.7	15.2	3.9	-3.8	-3.5	-3.7	-3.5	-3.6	3.7	-3.7	-0.8	-2.8	-3.4	-3.6	-3.1	-3.6	-3.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.7	1.8	-1.0	1.1	1.1	0.9	0.6	1.0	-1.0	0.8	0.9	-0.3	0.5	1.4	-0.3	0.9	0.3
Glaucoma (self-reported)	1.8	2.2	4.8	-1.0	1.6	2.2	1.3	1.8	1.4	-1.5	1.6	2.0	-0.2	1.5	1.3	1.4	1.4	0.3
Gout (self-reported)	5.6	7.7	10.5	-2.8	3.0	3.0	2.9	2.5	2.8	-2.8	2.8	2.8	1.7	3.2	2.7	2.9	2.9	2.1
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	2.4	0.6	-1.0	-0.3	-1.0	-1.1	-1.1	1.1	-1.1	1.4	-1.6	-0.9	-1.0	-1.3	-1.1	-1.2
Medication: Amlodipine	1.5	2.0	4.0	1.7	-1.6	-1.1	-1.7	-1.5	-1.6	1.4	-1.2	-2.0	-0.6	-1.7	-1.7	-0.7	-1.4	-0.8
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.8	0.5	-0.3	0.4	-0.6	-0.9	-0.5	0.3	-0.2	-0.1	-0.6	-0.4	-0.4	-0.5	-0.3	-0.4
Birth weight	2.1	4.6	6.3	-1.7	2.2	2.1	2.1	2.1	2.3	-2.1	2.3	1.6	1.9	2.4	2.2	2.5	2.2	2.2
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.2	0.2	-0.4	0.2	-0.6	-0.3	-0.5	0.4	-0.4	0.3	-1.1	-0.6	-0.6	-0.6	-0.4	-0.9
High blood pressure (siblings)	0.3	0.5	2.0	0.5	-0.7	-0.6	-0.7	-0.8	-0.7	0.4	-0.4	-1.3	0.1	-1.4	-0.5	-0.4	-0.5	-0.0
Forced vital capacity (FVC), Best measure	0.1	0.5	2.0	0.4	0.3	1.2	0.3	0.4	0.2	-0.0	0.4	1.4	-0.7	1.2	0.4	1.0	-0.0	-0.2
Body fat percentage	3.4	13.2	17.8	4.1	-3.7	-2.8	-4.0	-3.9	-4.0	4.0	-3.9	-0.5	-3.9	-2.8	-4.2	-3.4	-4.0	-3.8
Leg fat percentage (right)	3.5	12.8	15.6	3.8	-3.7	-3.0	-3.9	-3.9	-3.8	3.7	-3.8	-1.5	-3.4	-3.6	-3.9	-3.8	-3.7	-3.5
Arm fat-free mass (right)	0.3	1.5	5.2	1.0	-0.2	1.6	-0.4	-0.5	-0.8	0.8	-0.2	2.3	-1.9	1.8	-0.6	1.6	-0.7	-1.4
Exposure to tobacco smoke outside home	0.2	0.3	1.2	0.3	-0.4	-0.5	-0.5	-0.4	-0.3	0.3	-0.4	-0.6	-0.2	-1.1	-0.3	-1.0	-0.3	-0.3
Comparative body size at age 10	0.5	1.2	1.9	1.1	-1.3	-0.7	-1.1	-0.9	-1.3	1.2	-1.2	-0.2	-1.0	-1.4	-1.2	-1.2	-1.2	-1.2
Number of full brothers	0.4	0.5	0.8	-0.8	0.7	0.9	0.8	0.9	0.7	-0.7	0.8	0.0	0.4	0.2	0.7	0.5	0.7	0.6
Worry too long after embarrassment	1.0	1.7	3.8	-1.1	1.0	-0.1	1.0	1.3	1.0	-1.0	1.0	-1.7	1.9	1.7	1.1	2.0	1.1	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.6	0.8	-1.1	-1.2	-0.7	-1.3	-1.1	1.1	-1.1	-0.6	0.2	-0.6	-1.2	-0.4	-1.0	-0.1
Wheeze or whistling in the chest in last year	0.2	0.3	1.4	0.7	-0.6	-0.3	-0.7	-1.2	-0.6	0.6	-0.4	0.5	-0.4	-0.1	-0.5	0.4	-0.6	-0.6
Number of children fathered	0.6	0.6	1.2	-1.0	0.8	0.8	0.8	0.8	0.9	-0.7	0.8	0.9	0.3	1.1	0.9	0.7	0.7	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	3.1	0.4	-0.6	-0.7	-0.5	-0.1	-0.5	0.5	-0.7	0.1	-0.7	-1.8	-0.4	-1.6	-0.4	-0.6
Age at first live birth	0.1	0.1	0.6	-0.3	-0.1	-0.1	-0.0	0.1	0.2	-0.1	0.2	-0.3	0.7	-0.2	0.1	0.4	0.0	0.8
Pulse wave peak to peak time	0.3	0.3	1.0	-0.1	0.6	0.4	0.5	0.8	0.6	-0.5	0.5	-0.5	0.5	1.0	0.6	0.4	0.5	0.5
Health satisfaction	0.8	1.0	2.7	-0.7	1.0	1.2	1.0	0.8	1.0	-1.0	1.3	0.6	0.9	0.9	1.1	1.6	1.0	0.9
Shortness of breath walking on level ground	0.6	0.7	1.2	-0.6	1.0	1.0	1.0	0.4	1.0	-0.9	0.9	1.1	0.4	0.9	1.0	0.6	0.8	0.8
Qualifications: College or University degree	1.4	4.5	10.1	2.2	-2.4	-2.5	-2.2	-2.1	-2.1	2.1	-2.1	-3.2	-0.6	-2.5	-2.1	-1.6	-2.2	-1.1
Eye problems/disorders: None of the above	0.5	0.5	0.9	0.5	-0.8	-0.8	-0.8	-1.0	-0.7	0.8	-0.7	0.8	-0.6	-0.6	-0.7	-0.6	-0.8	-0.8
Mouth/teeth dental problems: Loose teeth	4.1	4.8	7.3	-1.8	2.1	2.4	2.3	1.9	2.0	-2.0	2.2	2.2	2.1	2.6	2.1	2.7	2.1	2.2
Emphysema/chronic bronchitis	5.0	5.6	11.5	2.3	-2.5	-1.7	-2.4	-2.1	-2.3	2.4	-2.2	-0.6	-2.6	-3.4	-2.0	-3.1	-2.4	-2.4
Medication for pain relief, constipation, heartburn	0.7	1.3	2.6	1.4	-1.1	-0.5	-1.1	-0.6	-1.0	1.2	-1.1	-0.9	-1.5	-1.0	-0.9	-1.2	-1.2	-1.6
Neck or shoulder pain in last month	0.5	0.6	2.2	0.5	-0.6	-1.1	-0.6	-1.0	-0.7	0.8	-0.9	1.5	-0.5	0.4	-0.9	-0.2	-0.8	-0.8
Medication: Blood pressure	1.6	2.8	4.3	1.7	-2.0	-1.9	-1.7	-1.8	-1.8	1.8	-1.6	-2.1	-0.3	-2.0	-2.0	-0.8	-1.7	-0.8
Angina (self-reported)	0.9	1.2	3.7	-1.0	0.9	0.3	1.1	0.9	0.9	-1.0	1.0	0.5	1.9	0.7	1.0	1.5	1.0	1.7
Migraine (self-reported)	4.5	5.6	7.8	2.8	-2.5	-2.3	-2.6	-2.6	-2.6	2.6	-2.5	-1.2	-2.2	-1.5	-2.7	-1.4	-2.6	-2.6
Medication: Ibuprofen	0.2	0.2	0.4	-0.6	0.6	0.2	0.5	-0.2	0.4	-0.5	0.5	0.4	0.4	0.6	0.4	0.6	0.5	0.5
Medication: Allopurinol	1.5	1.9	3.8	-1.5	1.6	1.9	1.5	1.1	1.3	-1.3	1.4	1.4	0.3	1.9	1.3	1.6	1.4	0.7
Medication: Omeprazole	0.5	0.6	1.3	0.4	-0.7	-0.9	-0.7	-1.1	-0.8	0.8	-0.9	1.1	-0.5	-0.2	-0.8	-0.8	-0.8	-0.7
Medication: Seretide 50 evohaler	2.4	2.7	7.2	-1.9	1.5	1.9	1.6	2.7	1.9	-1.5	1.6	0.5	1.2	1.5	1.6	1.4	1.6	1.4
Mean time to correctly identify matches	1.3	2.4	5.1	1.4	-1.6	-1.1	-1.7	-0.8	-1.3	1.5	-1.3	-2.2	-1.6	-2.3	-1.6	-1.5	-1.3	-1.5
Heart disease (mother)	0.2	0.3	1.8	-0.2	-0.3	0.1	-0.1	-0.3	-0.1	-0.0	0.2	-1.3	0.3	-1.2	-0.0	0.0	-0.0	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.0	-0.9	0.8	0.5	0.7	1.0	0.9	-0.9	0.8	-0.9	1.0	0.6	0.8	0.8	0.9	0.9
Whole body fat mass	3.1	13.1	18.9	4.3	-3.7	-2.1	-3.9	-3.8	-4.1	4.1	-3.8	0.0	-4.3	-2.1	-4.2	-2.7	-4.1	-4.2
Leg fat mass (right)	2.8	11.0	16.4	3.8	-3.4	-2.0	-3.6	-3.5	-3.7	3.6	-3.5	-0.2	-4.0	-2.2	-3.8	-2.8	-3.6	-3.9
Arm predicted mass (right)	0.3	1.5	5.9	1.0	-0.2	1.6	-0.3	-0.5	-0.7	0.7	-0.2	2.4	-1.9	1.9	-0.5	1.6	-0.7	-1.4
Pulse rate, automated reading	0.1	0.3	3.7	0.2	-0.2	0.1	0.0	0.6	0.3	0.2	-0.2	-1.9	-0.1	-0.1	0.2	-0.3	-0.1	-0.1
Alcohol intake frequency.	3.0	7.0	10.1	3.1	-2.9	-2.2	-3.0	-2.5	-3.0	3.1	-2.9	-0.5	-2.6	-1.3	-3.2	-1.6	-3.0	-3.0
Comparative height size at age 10	0.9	4.9	26.1	-1.0	1.6	3.0	1.3	1.3	1.1	-1.1	1.7	5.1	-0.4	3.1	1.1	3.7	1.1	0.5
Number of full sisters	0.2	0.2	2.3	0.2	-0.1	0.2	-0.1	0.2	0.1	-0.1	0.3	1.5	0.2	-0.7	0.1	-0.0	0.0	0.1
Suffer from ‘nerves’	1.1	1.8	3.7	-1.5	1.1	0.8	1.4	1.1	1.1	-1.3	1.4	-0.6	1.8	1.0	1.4	1.9	1.3	1.6
Overall health rating	0.6	1.4	3.5	-0.9	1.1	1.1	1.1	0.7	0.9	-1.1	1.3	1.7	1.1	1.0	0.9	1.9	1.2	1.1
Chest pain or discomfort	0.4	0.5	1.9	-0.9	0.7	1.2	0.6	0.1	0.6	-0.6	0.9	-0.1	-0.0	0.9	0.6	1.4	0.6	0.2
Had major operations	1.0	1.1	3.0	1.3	-0.8	-0.3	-1.0	-1.2	-0.9	1.1	-1.0	-0.0	-1.7	-0.5	-0.9	-1.2	-1.1	-1.5
Age at last live birth	0.1	0.1	0.4	-0.1	-0.1	0.1	0.1	0.6	0.2	0.0	0.1	0.3	0.7	0.2	0.1	0.4	-0.0	0.6
Family relationship satisfaction	2.0	2.5	3.7	-1.5	1.5	0.9	1.5	1.5	1.6	-1.5	1.5	1.4	1.9	1.7	1.6	1.9	1.5	1.7
Leg pain on walking	0.3	0.4	0.6	-0.7	0.7	0.2	0.6	-0.0	0.7	-0.8	0.7	0.0	0.6	0.6	0.8	0.7	0.7	0.4
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	3.7	1.0	-1.4	-1.0	-1.4	-1.4	-1.4	1.4	-1.5	-1.5	-1.9	-1.5	-1.5	-1.9	-1.3	-1.8
Commuting to job workplace: Car/motor vehicle	0.2	0.2	2.1	-0.2	0.1	-0.2	-0.1	0.1	-0.0	-0.1	-0.2	1.5	-0.2	-0.0	-0.2	-0.8	0.0	-0.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	-1.1	0.6	1.3	0.6	1.1	0.7	-0.5	0.5	0.7	-0.5	0.7	0.7	0.1	0.5	-0.1
Medication: Aspirin	0.3	0.4	2.2	-0.4	0.3	-0.2	0.4	0.2	0.4	-0.3	0.5	0.1	1.5	0.5	0.4	1.2	0.4	1.1
Supplements: Vitamin C	5.0	5.9	8.0	-2.7	2.8	2.7	2.4	2.6	2.7	-2.8	2.7	1.6	1.5	1.9	2.4	2.0	2.8	2.0
Knee pain experienced in last month	0.0	0.1	0.4	-0.3	-0.1	-0.2	-0.0	-0.1	0.0	0.0	-0.2	0.1	0.1	-0.3	-0.1	-0.7	-0.0	0.1
Hypertension (Self-reported)	0.9	2.6	9.6	1.4	-1.7	-1.5	-1.6	-2.2	-1.6	1.5	-1.3	-3.1	-0.3	-1.4	-1.8	-0.2	-1.5	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.5	0.7	-0.3	-0.5	-0.5	-0.1	-0.3	0.4	-0.3	-0.5	-0.2	0.5	-0.2	0.4	-0.4	-0.3
Illnesses of father: Heart disease	2.6	3.5	5.1	-2.3	2.1	1.6	1.8	1.6	2.1	-2.2	2.1	0.4	1.9	1.7	1.9	1.7	2.2	2.0
Illnesses of siblings: Diabetes	2.2	2.8	5.4	1.5	-1.5	-1.5	-1.8	-1.8	-1.8	1.8	-1.8	0.3	-2.2	-0.3	-1.9	-1.2	-1.7	-2.3
Smoking status: Previous	0.1	0.2	1.0	0.4	-0.5	-0.2	-0.4	-0.2	-0.3	0.4	-0.2	-1.0	0.2	-0.9	-0.1	-0.3	-0.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	12.6	0.3	0.6	0.9	0.3	0.4	0.2	-0.2	0.8	2.1	0.6	3.0	0.5	3.5	0.2	0.4
Whole body fat-free mass	0.6	3.4	10.5	2.1	-1.3	0.9	-1.5	-1.5	-1.9	2.0	-1.3	1.7	-3.2	1.3	-1.7	0.9	-1.9	-2.7
Leg fat-free mass (right)	0.8	4.3	12.1	2.6	-1.7	0.5	-1.9	-1.7	-2.3	2.3	-1.7	1.6	-3.5	1.2	-2.1	0.5	-2.3	-3.1
Arm fat percentage (left)	4.7	18.7	23.9	4.9	-4.5	-3.2	-4.7	-4.3	-4.7	4.7	-4.6	-1.2	-4.8	-3.3	-4.9	-4.0	-4.7	-4.8
Average weekly red wine intake	0.2	0.3	4.6	-0.0	-0.1	-0.2	-0.1	0.1	-0.0	0.0	0.2	-2.1	0.2	-0.2	0.1	0.5	-0.0	0.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.3	-0.5	0.4	0.6	0.5	0.1	0.4	-0.5	0.3	1.1	0.1	-0.9	0.5	-0.8	0.5	0.5
Mood swings	0.1	0.1	0.7	0.3	-0.2	-0.3	-0.1	-0.2	-0.4	0.3	-0.3	-0.8	0.4	0.4	-0.4	0.4	-0.3	0.1
Loneliness, isolation	0.8	1.1	1.8	-1.1	1.0	0.7	1.1	1.1	1.0	-1.1	1.0	0.5	1.4	0.5	1.2	0.8	1.1	1.3
Long-standing illness, disability or infirmity	0.4	0.6	1.0	0.9	-0.8	-0.7	-1.0	-1.0	-0.9	0.8	-0.6	-0.4	-0.6	-0.3	-1.0	0.3	-0.7	-0.7
Ever had bowel cancer screening	0.7	0.9	3.4	-1.0	0.6	0.4	0.9	0.3	0.6	-0.6	0.6	1.8	1.2	1.4	0.7	1.1	0.5	1.0
Diabetes diagnosed by doctor	2.5	4.1	8.5	2.0	-1.9	-0.8	-2.0	-2.1	-2.1	2.1	-2.1	0.7	-2.9	-1.3	-2.1	-2.2	-2.1	-2.7
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.9	3.4	1.8	-1.4	-1.7	-1.1	-1.4	-1.3	1.3	-1.4	-1.4	-0.3	-1.8	-1.3	-1.5	-1.3	-0.5
Friendships satisfaction	0.0	0.0	0.2	-0.2	-0.0	-0.4	0.1	0.2	-0.0	0.1	-0.0	-0.4	0.3	0.1	0.2	0.1	-0.1	0.1
Qualifications: nursing, teaching	2.5	3.9	5.2	1.8	-2.2	-1.6	-2.3	-2.1	-2.1	2.1	-2.0	-2.3	-1.7	-1.6	-2.2	-1.2	-2.1	-2.0
Commuting to job workplace: Walk	0.6	0.6	5.7	0.4	-0.5	-0.1	-0.5	-0.5	-0.4	0.5	-0.4	-2.4	-1.0	-0.3	-0.6	-0.0	-0.5	-0.8
Eye problems/disorders: Cataract	0.2	0.2	1.7	-0.0	0.2	0.2	0.2	0.1	0.1	-0.3	0.3	-1.3	0.6	-0.0	0.1	0.3	0.3	0.7
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	4.5	0.8	-1.3	-2.1	-1.0	-1.5	-1.2	1.2	-1.2	-1.6	0.7	-0.8	-1.0	-0.4	-1.2	0.1
Medication for cholesterol	0.4	0.7	5.2	-0.3	0.4	1.0	0.7	0.8	0.5	-0.4	0.2	2.3	-0.4	-0.2	0.6	-1.0	0.4	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	4.0	-1.1	1.1	0.4	1.2	1.0	0.9	-1.0	0.7	2.0	1.5	1.6	0.8	0.6	1.1	1.3
Back pain experienced in last month	0.2	0.3	1.1	0.5	-0.2	0.3	-0.4	-0.6	-0.5	0.3	-0.2	1.0	-1.1	0.0	-0.5	-0.2	-0.3	-0.7
Mineral and other dietary supplements	0.2	0.3	1.5	-0.7	0.4	1.1	0.3	0.6	0.4	-0.3	0.6	1.2	-0.2	0.1	0.6	0.5	0.3	0.1
Breast cancer (self-reported)	0.7	0.9	2.0	1.2	-0.9	-0.2	-0.8	-0.8	-0.6	0.9	-0.7	-0.3	-1.4	-1.4	-0.6	-1.2	-0.8	-1.0
Asthma (self-reported)	0.4	0.7	2.9	-0.8	0.7	1.7	0.5	0.4	0.6	-0.5	0.7	0.8	-0.4	1.6	0.5	1.2	0.5	-0.2
Osteoporosis (self-reported)	0.2	0.2	0.4	0.5	-0.5	-0.6	-0.6	-0.4	-0.5	0.5	-0.5	0.1	0.1	-0.5	-0.5	-0.6	-0.5	0.0
Osteoarthritis (self-reported)	4.0	5.1	7.0	-2.6	2.3	1.9	2.3	1.4	2.3	-2.3	2.4	2.4	2.3	2.1	2.0	2.6	2.4	2.4
Medication: Aspirin	0.5	0.7	2.7	-0.7	0.4	0.0	0.7	0.5	0.6	-0.5	0.7	0.2	1.6	0.6	0.6	1.3	0.6	1.4
Medication: Gliclazide	0.5	0.5	3.2	0.5	-0.4	0.1	-0.3	-0.2	-0.5	0.6	-0.6	1.8	-1.1	0.3	-0.5	-0.6	-0.6	-1.0
Illnesses of father: None of the above (group 1)	0.5	0.6	0.9	-0.5	0.9	0.9	0.9	0.7	0.8	-0.8	0.7	0.9	0.4	0.9	0.8	0.2	0.8	0.8
Smoking status: Current	5.2	8.3	10.7	-3.2	3.2	2.9	3.1	3.1	3.1	-3.3	3.3	1.8	1.9	2.3	3.2	2.5	3.3	2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	3.0	-0.1	0.5	0.5	0.5	0.5	0.5	-0.4	0.3	1.7	-0.1	0.9	0.6	0.0	0.3	-0.0
Whole body water mass	0.6	3.6	11.1	2.2	-1.4	0.8	-1.6	-1.6	-2.0	2.0	-1.4	1.7	-3.3	1.2	-1.7	0.8	-2.0	-2.8
Leg predicted mass (right)	0.8	4.3	11.9	2.5	-1.6	0.6	-1.8	-1.7	-2.2	2.3	-1.6	1.7	-3.5	1.2	-2.1	0.6	-2.3	-3.1
Arm fat mass (left)	3.9	15.9	23.8	4.6	-4.1	-2.3	-4.3	-4.0	-4.4	4.5	-4.2	-0.4	-4.9	-2.4	-4.5	-3.1	-4.5	-4.8
Number of self-reported non-cancer illnesses	0.5	0.8	1.8	0.5	-1.0	-0.9	-1.1	-1.3	-1.0	0.9	-0.7	-1.0	-0.1	-0.3	-1.4	0.7	-0.8	-0.5
Average weekly champagne plus white wine intake	0.2	0.2	0.4	-0.6	0.5	0.4	0.5	-0.0	0.6	-0.6	0.5	-0.6	0.0	-0.4	0.5	-0.2	0.5	0.3
Miserableness	0.2	0.3	1.3	-0.5	0.3	0.2	0.6	0.0	0.3	-0.4	0.5	0.2	1.1	-0.1	0.4	0.8	0.4	1.0
Guilty feelings	2.0	3.1	7.6	-1.7	1.6	0.6	1.6	1.8	1.7	-1.8	1.7	-0.4	2.8	1.1	1.7	2.0	1.8	2.5
Wears glasses or contact lenses	4.1	4.8	6.7	2.1	-2.2	-2.0	-2.3	-2.4	-2.2	2.2	-2.4	-0.7	-2.1	-2.0	-2.4	-2.6	-2.3	-2.2
Ever taken oral contraceptive pill	0.2	0.2	2.2	0.2	0.1	-0.2	0.3	0.2	0.2	-0.1	-0.2	0.2	0.0	-0.6	0.3	-1.5	0.1	0.1
Hearing aid user	0.3	0.3	1.7	0.5	-0.2	0.2	-0.4	-0.4	-0.4	0.4	-0.4	1.3	-0.8	0.6	-0.3	-0.2	-0.4	-0.8
Mother’s age at death	1.6	2.0	6.8	0.7	-1.2	0.1	-1.4	-1.3	-1.2	1.4	-1.3	-1.2	-2.6	-0.9	-1.5	-1.5	-1.4	-2.1
Financial situation satisfaction	0.1	0.1	0.5	0.2	0.1	0.4	-0.1	0.6	0.2	-0.1	0.1	-0.7	-0.6	-0.5	0.1	-0.4	0.1	-0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.4	0.1	0.3	-0.1	-0.3	-0.2	0.0	0.0	-0.1	-0.5	0.3	-0.3	0.4	-0.0	-0.4
Commuting to job workplace: Public transport	2.2	2.6	3.8	1.5	-1.6	-1.1	-1.7	-1.4	-1.6	1.7	-1.5	-2.0	-1.9	-1.5	-1.6	-1.4	-1.6	-1.7
Eye problems/disorders: Glaucoma	0.3	0.3	1.0	-0.3	0.6	0.9	0.3	0.9	0.5	-0.5	0.6	1.0	-0.5	0.2	0.5	0.4	0.4	-0.1
Medication: Blood pressure	1.3	2.6	7.6	1.6	-1.6	-1.8	-1.7	-2.2	-1.5	1.5	-1.4	-2.8	-0.5	-1.1	-1.7	-0.5	-1.5	-1.0
Pain type(s) experienced in last month: Hip pain	1.0	1.2	3.3	1.3	-1.1	-1.4	-1.2	-1.2	-1.0	1.0	-0.9	-1.8	-0.5	-1.1	-1.0	-0.8	-1.0	-0.7
Supplements: Fish oil (including cod liver oil)	0.4	0.6	2.6	-0.2	0.9	0.3	0.7	0.6	0.6	-0.8	0.6	-0.6	0.5	1.6	0.5	1.2	0.7	0.4
High cholesterol (Self-reported)	0.1	0.1	0.6	-0.3	0.1	0.0	0.0	0.1	-0.0	-0.1	0.2	0.7	0.6	0.0	-0.1	0.8	0.1	0.5
Medication: Bendroflumethiazide	0.4	0.7	3.8	0.2	-0.7	-1.2	-0.7	-1.2	-0.7	0.7	-0.5	-1.9	0.5	-0.3	-0.6	0.2	-0.6	-0.0
Medication: Paracetamol	0.0	0.0	0.3	-0.3	0.2	-0.0	0.1	0.0	0.3	-0.2	0.2	0.5	0.2	-0.1	0.0	0.0	0.2	0.2
Medication: Lisinopril	0.6	0.8	1.4	1.0	-1.1	-0.9	-0.8	-1.1	-0.9	1.0	-0.9	-1.2	-0.2	-1.0	-1.1	-0.6	-0.9	-0.6
Medication: Atorvastatin	1.8	2.2	3.5	-1.6	1.5	1.5	1.4	1.1	1.6	-1.5	1.6	1.2	1.3	1.5	1.4	1.9	1.6	1.4
Illnesses of father: High blood pressure	1.5	1.8	3.2	1.4	-1.7	-1.8	-1.6	-1.6	-1.6	1.5	-1.2	-1.4	-0.0	-1.4	-1.3	-0.4	-1.4	-0.7
Alcohol drinker status: Never	0.6	0.7	1.2	0.8	-0.9	-0.8	-0.8	-0.9	-0.9	0.8	-0.8	-0.7	-0.5	-1.1	-0.9	-0.7	-0.8	-0.6
Ever smoked	0.6	1.0	4.3	-1.1	0.3	-0.4	0.5	0.5	0.7	-0.7	0.8	-2.1	1.7	-1.0	0.9	0.5	0.7	1.4
Basal metabolic rate	0.8	4.4	12.9	2.6	-1.7	0.5	-2.0	-1.9	-2.3	2.4	-1.7	1.5	-3.6	0.8	-2.1	0.4	-2.3	-3.1
Leg fat percentage (left)	3.4	12.3	15.2	3.8	-3.6	-3.0	-3.7	-3.8	-3.7	3.6	-3.8	-1.1	-3.3	-3.5	-3.8	-3.9	-3.6	-3.4
Arm fat-free mass (left)	0.3	1.7	4.8	1.3	-0.5	1.4	-0.7	-0.8	-1.0	1.0	-0.5	2.2	-2.2	1.6	-0.8	1.2	-1.0	-1.7
Number of operations (self-reported)	0.1	0.2	0.3	0.0	-0.3	-0.2	-0.4	-0.6	-0.5	0.4	-0.4	0.6	-0.3	0.4	-0.3	0.0	-0.5	-0.5
Average weekly beer plus cider intake	2.7	3.9	6.7	-1.9	2.2	2.6	2.2	2.2	2.1	-2.1	2.1	1.8	1.1	1.7	2.0	1.2	2.1	1.7
Irritability	0.5	0.9	3.3	-0.5	0.7	0.5	0.8	0.3	0.6	-0.7	0.8	-0.8	1.5	1.2	0.6	1.8	0.7	1.3
Risk taking	0.1	0.1	0.4	0.1	-0.2	-0.2	-0.2	-0.3	-0.3	0.2	-0.1	0.6	0.6	0.1	-0.1	0.5	-0.1	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.3	0.3	-0.4	-0.1	-0.4	-0.3	-0.4	0.3	-0.5	0.3	-0.7	-1.0	-0.5	-1.2	-0.3	-0.6
Fractured/broken bones in last 5 years	2.4	3.2	5.8	-2.4	1.7	1.2	1.6	1.2	1.5	-1.7	1.7	0.2	2.1	2.4	1.5	2.3	1.7	2.0
Age started oral contraceptive pill	1.0	1.2	4.3	0.8	-1.0	-1.7	-1.0	-0.9	-0.9	0.8	-1.0	-2.1	-0.3	-1.3	-0.9	-1.4	-0.9	-0.4
Diastolic blood pressure, automated reading	0.3	1.0	4.2	-0.6	0.7	1.0	0.6	0.6	0.7	-0.8	1.2	-1.1	1.3	0.5	0.7	2.0	0.9	1.1
Ever depressed for a whole week	0.4	0.5	1.3	-0.7	0.4	0.2	0.6	1.0	0.4	-0.6	0.6	0.5	1.2	0.2	0.5	0.8	0.6	1.0
Unable to work because of sickness or disability	0.6	0.7	3.7	-0.9	0.7	0.5	0.8	0.9	0.8	-0.8	0.7	1.9	0.7	0.7	0.6	0.7	0.8	0.6
Commuting to job workplace: Cycle	0.8	1.0	3.8	1.1	-1.0	-0.9	-0.9	-1.5	-1.0	1.0	-0.7	-2.0	-0.5	-0.8	-0.6	-0.2	-1.0	-0.5
Myopia	0.2	0.3	0.8	0.4	-0.4	-0.0	-0.5	-0.3	-0.6	0.5	-0.5	-0.4	-0.9	-0.3	-0.7	-0.4	-0.6	-0.7
Vascular/heart problems diagnosed by doctor	0.4	1.1	8.0	-0.7	0.9	1.0	0.9	1.3	0.8	-0.7	0.5	2.8	-0.6	0.8	1.0	-0.5	0.7	-0.2
Cholesterol lowering medication	0.0	0.1	0.3	-0.3	0.0	-0.2	0.0	-0.0	0.0	-0.2	0.3	-0.2	0.4	-0.5	0.1	0.3	0.1	0.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	2.2	0.5	-0.8	-1.0	-0.8	-1.0	-0.9	0.9	-1.0	1.5	-0.6	-0.6	-0.8	-1.1	-0.9	-0.7
Pain experienced in last month	0.2	0.3	0.9	-0.5	0.5	1.0	0.4	0.5	0.5	-0.4	0.5	-0.6	-0.1	0.6	0.5	0.6	0.4	0.2
Supplements: Calcium	0.2	0.2	0.7	-0.3	0.4	0.1	0.3	0.2	0.3	-0.5	0.5	-0.2	0.6	0.4	0.3	0.8	0.5	0.7
Basal cell carcinoma (self-reported)	0.6	0.7	1.9	0.3	-1.2	-1.4	-0.8	-0.7	-1.0	1.0	-1.0	-0.9	0.9	-0.5	-0.9	-0.2	-0.9	0.3
Heart attack/myocardial infarction (self-reported)	1.8	2.3	7.3	-1.2	1.3	0.3	1.4	1.4	1.5	-1.4	1.4	0.4	2.7	1.2	1.4	1.6	1.5	2.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.8	0.4	-0.6	-0.7	-0.5	-0.9	-0.7	0.5	-0.7	-0.5	-0.1	-0.4	-0.6	-0.7	-0.6	-0.3
Heart disease (siblings)	0.8	0.9	1.8	-0.5	0.9	1.2	0.7	1.3	0.9	-0.8	0.9	1.4	0.5	1.3	0.8	1.2	0.8	0.6
Alcohol drinker status: Previous	0.1	0.2	1.1	0.3	-0.1	0.0	-0.2	0.1	-0.1	0.1	-0.2	-1.0	-0.8	-0.3	-0.4	-0.3	-0.1	-0.5
Pack years of smoking	2.9	4.3	6.8	-2.5	2.3	2.4	2.5	2.6	2.6	-2.4	2.3	0.6	1.0	0.7	2.5	0.8	2.4	1.5
Impedance of whole body	0.3	1.3	4.0	-1.2	1.1	-0.3	1.0	0.6	1.2	-1.3	1.0	0.2	1.9	0.3	1.1	0.7	1.2	2.0
Leg fat mass (left)	2.8	10.9	15.4	3.8	-3.4	-2.0	-3.6	-3.5	-3.7	3.6	-3.5	-0.1	-3.9	-2.2	-3.7	-2.8	-3.6	-3.8
Arm predicted mass (left)	0.4	1.9	6.2	1.4	-0.7	1.2	-0.9	-1.1	-1.2	1.2	-0.7	2.0	-2.5	1.4	-1.1	0.9	-1.2	-2.0