TWAS hub - C1orf105

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Colon Adenocarcinoma	0.102	0.048	0.0013	0.015	0.042	0.024	NA	0.025	0.046	0.0018	0.015	NA	0.014
2	TCGA	Pancreatic Adenocarcinoma	0.135	0.061	0.0016	-0.006	0.033	0.002	NA	-0.006	0.760	0.0150	0.260	NA	0.660
3	TCGA	Rectum Adenocarcinoma	0.187	0.090	0.0088	0.006	0.092	0.054	NA	0.035	0.230	0.0036	0.021	NA	0.052

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Waist Hip Ratio (WHR)	14.8	66.5	127.7	3.2	11.3	-7.8
HbA1C	5.7	6.3	10.7	-1.1	3.3	-2.7
Osteoarthritis (self-reported)	5.2	6.7	10.0	1.1	-3.2	3.0
Diabetes (mother)	4.1	5.2	8.4	0.7	2.9	-2.6
Fasting Glucose	3.8	4.6	6.2	-2.4	1.5	-2.5
Age started oral contraceptive pill	3.7	4.6	10.6	-3.3	-0.5	-1.7
Ever highly irritable/argumentative for 2 days	3.6	4.3	8.1	1.6	-2.9	1.6
Sitting height	3.4	24.2	64.8	8.1	2.7	0.6
Medication: Seretide 50 evohaler	3.4	3.9	6.2	0.5	-2.5	2.3
Standing height	3.1	30.4	81.5	9.0	2.9	1.0
Supplements: Vitamin C	2.9	3.5	6.6	2.6	-0.7	1.8
Diastolic blood pressure, automated reading	2.8	8.7	16.4	-0.2	3.1	-4.0
Height	2.7	51.6	141.6	11.9	3.3	1.6
Average weekly red wine intake	2.7	4.0	5.9	-2.4	-2.3	0.8
Osteoporosis (self-reported)	2.6	3.2	7.3	2.7	0.8	1.4
Supplements: Fish oil (including cod liver oil)	2.6	3.4	6.4	1.5	-1.2	2.5
Sensitivity / hurt feelings	2.5	4.3	7.2	2.0	2.7	-1.2
Supplements: Glucosamine	2.5	3.2	4.8	1.0	-2.0	2.2
Number of children fathered	2.5	2.8	6.4	-2.5	-1.3	-0.6
Leg pain on walking	2.5	3.1	4.0	1.7	-1.5	2.0
Hearing aid user	2.5	2.8	7.5	-0.6	-2.7	0.7
Financial situation satisfaction	2.5	3.2	8.9	3.0	0.7	0.1
Medication: Aspirin	2.4	3.2	6.1	-1.4	1.2	-2.5
Medication for pain relief, constipation, heartburn	2.3	3.9	6.4	1.9	-1.3	2.5
Comparative height size at age 10	2.3	12.8	27.8	5.3	2.8	-1.8
Schizophrenia vs Biploar Disorder	2.2	2.9	4.7	-0.4	2.0	-2.2
Heel T-Score	2.2	17.8	48.7	-2.1	-7.0	0.3
Mouth/teeth dental problems: Dentures	2.2	3.7	5.7	1.4	-2.4	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	6.2	1.1	2.5	-1.1
Commuting to job workplace: Walk	2.2	2.4	5.7	-0.9	-2.4	0.8
Breast Cancer	2.1	5.2	5.8	2.4	2.1	-2.3
Bipolar Disorder (2011)	2.1	2.0	3.6	-0.9	-1.9	1.2
Alcohol usually taken with meals	2.0	3.2	6.1	-2.5	-1.9	-0.2
Hip circumference	2.0	8.5	19.9	-0.5	-4.5	2.3
Chronic bronchitis/emphysema (mother)	2.0	2.3	6.1	0.2	2.5	-0.9
Medication: Aspirin	2.0	2.7	5.1	-1.3	1.1	-2.3
Number of self-reported non-cancer illnesses	2.0	3.4	5.2	1.5	-1.6	2.3
Pain type(s) experienced in last month: Hip pain	2.0	2.5	5.0	1.1	-1.1	2.2
Maternal smoking around birth	1.9	2.7	4.8	2.2	-0.0	1.8
Trunk fat-free mass	1.9	10.7	25.8	5.1	2.4	-0.5
Mouth/teeth dental problems: Bleeding gums	1.9	2.5	7.1	-2.7	-0.5	-0.1
Trunk predicted mass	1.8	10.5	25.9	5.1	2.3	-0.4
Ever had bowel cancer screening	1.8	2.1	4.6	-2.1	-0.5	-1.2
LDL Cholesterol	1.7	2.7	4.0	-0.2	2.0	-2.0
Blood Red Count	1.7	16.4	27.2	3.3	5.2	-3.3
Fed-up feelings	1.7	3.2	8.4	2.9	1.0	0.2
Breastfed as a baby	1.7	2.1	5.2	-0.8	0.7	-2.3
Loud music exposure frequency	1.7	1.9	2.8	0.9	-1.7	1.4
Fractured/broken bones in last 5 years	1.7	2.1	5.0	2.2	1.1	0.3
Ever depressed for a whole week	1.7	2.1	3.6	1.9	-1.2	1.2
Cholesterol lowering medication	1.7	2.5	7.2	2.7	0.4	0.5
Lung FVC	1.6	8.1	21.4	-1.1	-4.6	1.3
Number of incorrect matches in round	1.6	2.7	4.1	-1.8	0.8	-2.0
Nervous feelings	1.6	3.0	6.8	2.6	1.0	1.0
Peak expiratory flow (PEF)	1.6	3.8	7.8	2.8	1.5	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	3.3	-1.4	0.5	-1.8
Medication: Gliclazide	1.6	1.9	5.5	2.4	0.2	-0.1
Prostate Cancer	1.5	2.1	5.6	-2.4	-0.2	-0.8
Respiratory disease	1.5	3.4	7.2	2.7	-0.2	1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	7.0	-2.6	-1.5	-1.1
Medication: Atenolol	1.5	1.8	3.1	0.4	1.5	-1.8
Diabetes (self-reported)	1.5	2.3	5.4	0.7	1.0	-2.3
Worrier / anxious feelings	1.5	2.8	4.2	2.0	2.0	0.3
Asthma	1.5	3.0	5.5	2.3	-0.4	1.9
Heart disease (mother)	1.5	1.8	2.8	-0.8	-1.7	1.4
Handedness (chirality/laterality): Left-handed	1.5	1.8	3.9	-2.0	-0.6	-1.1
Heart disease (siblings)	1.5	1.8	4.2	-0.8	0.8	-2.1
Mouth/teeth dental problems	1.4	2.2	4.4	1.0	2.1	-1.0
Pulse wave reflection index	1.4	1.7	2.4	1.4	1.6	-0.9
Commuting to job workplace: Car/motor vehicle	1.4	1.6	2.6	-0.9	1.2	-1.6
Major Depression (MDD)	1.3	1.6	2.8	1.7	-0.4	1.3
Triglycerides	1.3	2.1	3.0	1.7	1.7	-0.8
Age when periods started (menarche)	1.3	3.2	6.6	2.6	-0.5	1.7
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	3.0	-0.8	-1.1	1.7
Whole body fat-free mass	1.3	7.5	18.3	4.3	2.0	-0.5
Long-standing illness, disability or infirmity	1.3	2.0	2.9	1.3	-1.2	1.7
Medication for cholesterol	1.3	1.9	3.8	-2.0	-1.4	0.3
Mineral and other dietary supplements	1.3	1.7	2.2	-1.4	1.0	-1.5
Asthma (self-reported)	1.3	2.6	4.7	2.2	-0.2	1.7
Whole body water mass	1.3	7.6	18.1	4.2	2.1	-0.7
Medication: Paracetamol	1.3	2.0	4.2	-2.0	-0.4	-1.3
Taking other prescription medications	1.2	1.9	4.2	2.1	0.0	1.2
High blood pressure (siblings)	1.2	1.7	4.0	2.0	0.1	1.0
Arm fat-free mass (right)	1.2	6.3	16.2	4.0	1.5	-0.6
Arm predicted mass (right)	1.2	6.0	15.4	3.9	1.5	-0.6
Arm fat-free mass (left)	1.2	6.0	15.5	3.9	1.5	-0.6
Risk taking	1.2	1.7	3.3	-1.2	-1.8	0.7
Arm predicted mass (left)	1.2	6.2	14.9	3.9	1.7	-1.0
HDL Cholesterol	1.1	1.8	2.2	-1.4	-1.5	1.1
Neuroticism (2016)	1.1	1.5	3.9	2.0	-0.5	0.6
Blood Platelet Count	1.1	13.1	35.8	-6.0	-0.8	1.7
Chronic bronchitis/emphysema (father)	1.1	1.3	3.0	-0.7	-1.7	0.7
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	1.6	1.0	-1.2	1.3
Headache pain in last month	1.1	1.8	4.2	0.6	2.0	-1.0
Medication: Amlodipine	1.1	1.5	2.9	1.7	1.3	-0.1
Medication: Omeprazole	1.1	1.4	2.2	1.1	1.5	-0.9
Wears glasses or contact lenses	1.1	1.3	2.4	-0.8	1.0	-1.5
Medication: Bendroflumethiazide	1.1	1.6	3.4	0.2	1.8	-1.2
Basal metabolic rate	1.1	6.2	15.5	3.9	1.6	-0.6
Cardiovascular Disease	1.0	3.5	4.6	1.3	2.1	-2.0
Relative age of first facial hair	1.0	2.2	4.6	-0.7	2.2	-1.1
Hair/balding pattern: Pattern 2	1.0	1.3	3.6	0.5	0.0	1.9
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	2.7	0.5	-1.1	1.6
Alcohol intake versus 10 years previously	1.0	1.5	2.6	1.6	0.1	1.4
Tense / ‘highly strung’	1.0	1.7	4.4	2.1	0.7	0.5
Hair/balding pattern: Pattern 4	1.0	2.5	4.7	1.3	1.0	-2.2
Medication: Paracetamol	1.0	1.6	3.2	-1.8	-0.1	-1.3
Medication: Allopurinol	1.0	1.3	3.5	0.7	1.9	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	5.8	2.4	0.8	-0.2
Breast cancer (self-reported)	1.0	1.1	1.7	1.3	1.3	-0.3
Commuting to job workplace: Public transport	1.0	1.1	1.9	1.4	-0.1	1.2
Ever smoked	1.0	1.8	4.9	-0.2	-2.2	0.6
Basal cell carcinoma (self-reported)	1.0	1.2	1.7	1.3	0.5	1.3
Heart attack/myocardial infarction (self-reported)	1.0	1.4	2.6	0.1	1.2	-1.6
Lung FEV1/FVC ratio	0.9	4.6	10.6	1.4	3.2	-1.1
Leg predicted mass (left)	0.9	4.6	11.6	3.4	1.4	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	3.0	-1.7	-1.7	-0.1
Hair/balding pattern: Pattern 3	0.9	1.3	3.4	-0.2	1.9	-0.8
Forced expiratory volume in 1-second (FEV1)	0.9	3.1	9.3	3.0	-0.2	0.0
Back pain experienced in last month	0.9	1.3	3.6	1.9	-0.5	0.3
Eye problems/disorders: Glaucoma	0.9	1.1	2.5	0.8	1.6	-0.3
Commuting to job workplace: Cycle	0.9	1.1	1.2	1.0	-1.1	1.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	1.6	0.6	1.3	-1.1
Worry (Nagel 2018)	0.8	1.6	2.4	1.6	1.6	0.3
Body Mass Index (BMI) (2010)	0.8	1.2	2.7	-1.6	0.8	-0.4
BMI	0.8	4.5	10.0	-3.2	-1.3	-1.3
Chronotype (morning person)	0.8	1.9	2.0	1.4	1.4	1.3
Medication for hormone replacement therapy	0.8	0.9	2.7	-0.1	1.6	0.1
Leg fat-free mass (left)	0.8	4.4	11.0	3.3	1.4	-0.6
Current tobacco smoking	0.8	1.4	2.6	0.9	-0.8	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	1.5	1.1	0.9	-1.2
Forced vital capacity (FVC)	0.8	2.9	8.1	2.8	-0.7	0.3
Heart attack	0.8	1.0	2.0	0.2	1.0	-1.4
Neuroticism score	0.8	1.7	3.2	1.8	1.3	0.2
Father’s age at death	0.8	1.1	1.7	-1.3	-1.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.4	-1.2	-1.2	-0.3
Medication: Lansoprazole	0.8	0.9	1.3	-0.5	-1.1	-1.1
Birth weight	0.8	1.7	3.7	0.9	0.7	-1.9
Emphysema/chronic bronchitis	0.8	0.9	1.9	1.4	0.3	0.9
Mean time to correctly identify matches	0.8	1.5	3.0	-0.4	-1.7	1.1
Number of full sisters	0.8	1.0	1.9	1.4	-0.7	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	1.4	0.7	-1.2	0.9
Illnesses of siblings: Diabetes	0.8	0.9	1.4	-1.2	-0.2	1.1
Leg fat-free mass (right)	0.8	4.3	9.5	3.1	1.8	-0.5
Leg predicted mass (right)	0.8	4.5	9.7	3.1	1.9	-0.5
Medication: Blood pressure	0.8	1.5	2.3	1.5	1.3	-0.6
Number of operations (self-reported)	0.8	1.2	1.5	-1.0	1.2	-1.1
Average weekly beer plus cider intake	0.8	1.1	1.6	1.3	0.6	1.1
Bipolar Disorder (2018)	0.7	1.1	3.4	-1.8	-0.1	-0.2
Schizophrenia (2018)	0.7	1.4	2.3	-0.1	-1.4	1.5
Alzheimer’s Disease (in father)	0.7	0.7	1.0	0.8	0.8	1.0
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.8	0.7	-0.8	1.3
Townsend deprivation index at recruitment	0.7	0.9	2.5	1.6	0.6	0.2
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.1	-0.5	-1.4	0.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.4	1.2	1.0	0.0
Medication: Levothyroxine sodium	0.7	1.2	3.5	0.4	-1.9	0.1
Birth weight of first child	0.7	1.3	1.9	-1.4	1.0	-1.1
Blood clot in the leg (DVT)	0.7	0.9	2.4	-1.5	-0.6	0.0
Leg fat percentage (right)	0.7	2.5	5.5	-1.4	-2.4	-0.0
Angina (self-reported)	0.7	0.9	1.9	1.4	-0.5	0.7
Knee pain experienced in last month	0.7	1.1	1.9	0.7	-1.0	1.4
Arm fat percentage (left)	0.7	2.7	5.4	-2.3	-1.4	-0.9
Leg fat percentage (left)	0.7	2.4	4.2	-1.7	-2.0	0.1
Unable to work because of sickness or disability	0.7	0.9	1.5	1.2	1.0	0.1
Alzheimer’s Disease (in mother)	0.6	0.7	1.3	0.8	1.1	0.2
Ovarian Cancer	0.6	0.7	0.9	-1.0	0.8	-0.8
Mean Putamen Volume	0.6	0.7	1.2	-0.6	1.1	-0.6
Ulcerative Colitis	0.6	0.9	2.5	-1.6	0.4	0.4
Systolic Blood Pressure	0.6	2.8	6.8	1.2	2.6	-0.5
Angina	0.6	0.8	2.1	1.4	-0.3	0.6
Medication: Metformin	0.6	0.8	1.1	1.1	0.7	-0.9
Impedance of leg (right)	0.6	2.7	3.6	1.9	-1.6	1.5
Serious illness, injury or assault to yourself	0.6	0.8	2.2	1.5	-0.2	-0.2
Multivitamins +/- minerals	0.6	0.7	1.4	-0.8	-0.3	-1.2
Waist circumference	0.6	2.3	4.5	0.7	1.4	-2.1
Had other major operations	0.6	0.7	1.1	0.3	-1.1	0.9
Medication: Ramipril	0.6	0.8	1.2	0.2	-1.1	1.1
Arm fat percentage (right)	0.6	2.2	4.2	-2.1	-1.2	-1.0
Number of live births	0.6	0.8	1.2	1.0	-0.6	-1.1
Illnesses of mother	0.6	0.7	1.2	0.9	-0.3	1.1
Exposure to tobacco smoke at home	0.6	0.7	1.5	1.2	-0.2	0.7
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.3	-0.5	0.6	-1.5
Wheeze or whistling in the chest in last year	0.6	1.1	2.0	1.4	0.2	1.1
Mouth/teeth dental problems: Loose teeth	0.6	0.8	1.8	0.3	1.3	0.6
Illnesses of father: Heart disease	0.6	0.9	2.2	1.5	0.5	-0.5
Loneliness, isolation	0.6	0.8	1.1	1.1	-0.4	1.0
Diabetes diagnosed by doctor	0.6	1.0	2.2	0.5	0.8	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	2.4	-1.0	-1.6	-0.6
Guilty feelings	0.6	0.9	1.7	1.0	-0.3	1.3
Ever taken oral contraceptive pill	0.6	0.7	1.6	-0.8	-1.3	-0.0
Medication: Lisinopril	0.6	0.7	1.6	0.1	0.8	-1.3
Illnesses of father: High blood pressure	0.6	0.8	1.5	1.2	0.8	0.5
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.8	-1.3	-0.8	0.1
Bipolar Disorder or Schizophrenia	0.5	1.3	1.5	-1.2	-1.1	1.1
Intelligence (Savage-Jansen 2018)	0.5	1.5	2.9	0.2	1.3	-1.7
Primary Biliary Cirrhosis	0.5	0.7	0.9	-0.8	-0.7	-1.0
Vitamin and mineral supplements	0.5	0.7	1.8	-0.1	1.3	-0.5
Medication: Co-codamol	0.5	0.6	1.4	0.6	-1.2	0.3
Hand grip strength (right)	0.5	1.5	2.8	0.9	1.7	-0.9
Relative age voice broke	0.5	0.7	1.3	-1.1	0.1	0.9
High blood pressure (mother)	0.5	0.7	1.1	0.9	0.4	-1.0
Body mass index (BMI)	0.5	2.1	3.9	-2.0	-1.0	-1.2
Allergy	0.5	1.2	2.3	-1.5	-0.2	-1.1
Happiness	0.5	0.7	1.2	0.2	-0.9	1.1
Lung cancer (father)	0.5	0.6	1.7	0.4	-0.3	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	3.9	2.0	-0.2	-0.6
Forced vital capacity (FVC), Best measure	0.5	1.9	3.6	1.9	-1.4	0.4
Exposure to tobacco smoke outside home	0.5	0.7	1.0	1.0	1.0	0.2
Comparative body size at age 10	0.5	1.3	2.0	-1.4	-1.2	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.5	0.0	-1.2	0.4
Shortness of breath walking on level ground	0.5	0.6	1.0	1.0	-0.9	0.2
Neck or shoulder pain in last month	0.5	0.8	1.2	-0.8	-1.1	0.7
Age at last live birth	0.5	0.8	2.3	-1.5	0.2	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.5	0.5	0.4	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.2	0.1	1.1	-0.7
Average weekly champagne plus white wine intake	0.5	0.7	1.9	-1.4	0.2	-0.3
Medication: Atorvastatin	0.5	0.6	0.8	0.5	-0.9	0.9
Irritability	0.5	0.8	1.8	1.3	0.5	-0.6
Supplements: Calcium	0.5	0.5	1.2	0.4	0.5	1.1
Neuroticism (Nagel 2018)	0.4	1.0	1.9	1.4	1.0	0.2
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.3	0.2	0.8	-1.5
Coronary Artery Disease (CAD)	0.4	0.5	1.0	-1.0	-0.1	-0.7
Number of treatments/medications taken	0.4	0.7	2.0	1.4	0.1	0.0
Hearing difficulty/problems: Yes	0.4	0.6	1.6	-0.3	-1.3	-0.2
Diabetes (father)	0.4	0.5	0.9	-0.4	0.9	-0.7
Average weekly fortified wine intake	0.4	0.5	1.3	-1.2	0.1	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.7	0.6	0.7	-0.8
Had menopause	0.4	0.5	0.7	0.2	-0.9	0.8
Weight	0.4	1.8	5.2	2.3	0.1	-0.5
Time employed in main current job	0.4	0.5	0.7	0.6	0.7	-0.8
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.5	-0.9	-1.2	-0.6
Prospective memory result	0.4	0.5	0.8	-0.9	0.4	-0.7
Pulse wave Arterial Stiffness index	0.4	0.4	0.6	0.8	0.4	-0.7
Length of working week for main job	0.4	0.4	0.5	0.7	0.3	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.7	1.3	0.2	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.4	0.4	-0.2	1.2
Body fat percentage	0.4	1.8	2.8	-1.5	-1.7	-0.6
Number of full brothers	0.4	0.5	0.6	0.6	0.7	0.8
Smoking status: Current	0.4	0.7	1.3	0.8	-0.4	1.1
Alcohol drinker status: Never	0.4	0.5	1.3	-1.1	0.2	-0.4
Myopia	0.4	0.6	1.3	0.4	1.2	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.0	1.4	-1.2	-1.0	0.8
Impedance of whole body	0.4	1.8	2.9	0.9	-1.3	1.7
Crohns Disease (2012)	0.3	0.5	1.3	-1.1	0.2	0.4
Rheumatoid Arthritis	0.3	0.4	1.0	0.2	1.0	0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.8	0.4	0.9	-0.4
Allergy or Eczema	0.3	0.9	2.4	1.6	0.2	0.4
Hypothyroidism (self reported)	0.3	0.7	1.3	0.9	0.2	-1.1
Hand grip strength (left)	0.3	0.9	1.3	1.0	1.1	-0.6
Ever had hysterectomy (womb removed)	0.3	0.3	0.6	0.8	0.2	0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.7	-0.0	-0.4	-0.9
Pack years adult smoking proportion	0.3	0.4	0.7	0.1	-0.8	0.8
High blood pressure	0.3	0.8	1.9	1.4	0.6	-0.4
Impedance of leg (left)	0.3	1.6	2.2	1.3	-0.9	1.5
Past tobacco smoking	0.3	0.5	1.1	-0.7	1.1	-0.1
Financial difficulties in last 2 years	0.3	0.4	0.9	0.5	-0.1	-1.0
Impedance of arm (right)	0.3	1.5	2.4	0.7	-1.3	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.7	0.6	0.8	-0.5
Impedance of arm (left)	0.3	1.5	2.5	0.7	-1.2	1.6
Glaucoma (self-reported)	0.3	0.3	0.7	-0.3	0.8	-0.3
Gout (self-reported)	0.3	0.4	1.0	-0.5	1.0	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.4	1.2	-0.0	-0.2
Pulse wave peak to peak time	0.3	0.3	0.6	-0.3	-0.4	0.8
Migraine (self-reported)	0.3	0.4	1.1	-0.1	1.0	0.0
Suffer from ‘nerves’	0.3	0.5	0.7	0.8	0.5	0.7
Had major operations	0.3	0.3	0.6	-0.7	0.5	-0.3
Hypertension (Self-reported)	0.3	0.8	1.8	1.4	0.6	-0.5
Smoking status: Previous	0.3	0.5	0.7	0.8	-0.8	0.2
Qualifications: nursing, teaching	0.3	0.5	1.3	-0.2	-1.2	0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.9	-0.7	0.3	-1.0
Illnesses of father: None of the above (group 1)	0.3	0.3	1.0	-1.0	-0.0	-0.1
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.7	-0.3	0.2	-0.9
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	0.0	-0.3	1.0
Pain experienced in last month	0.3	0.5	0.6	-0.7	0.8	-0.6
Alcohol drinker status: Previous	0.3	0.4	1.0	-0.0	1.0	0.3
Depression (Nagel 2018)	0.2	0.3	0.6	0.8	0.4	-0.4
Ulcerative Colitis (UC)	0.2	0.5	1.0	-0.6	1.0	-0.2
Age at First Birth	0.2	0.3	0.5	-0.5	-0.7	-0.4
Lupus	0.2	0.3	0.8	0.9	-0.3	0.2
Blood White Count	0.2	1.8	5.1	-2.2	-0.6	-0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.3	0.1	0.1	-1.1
Average weekly spirits intake	0.2	0.3	0.4	0.6	-0.6	-0.3
Supplements: Zinc	0.2	0.3	0.6	0.4	0.8	0.1
Severe depression (siblings)	0.2	0.2	0.7	-0.9	0.1	0.0
Trunk fat percentage	0.2	1.0	2.1	-0.8	-1.4	-0.4
Qualifications: CSEs or equivalent	0.2	0.3	0.8	0.1	0.9	-0.3
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.9	1.0	0.6	-0.0
Qualifications: None of the above	0.2	0.4	0.6	-0.4	0.6	0.8
Medication: Simvastatin	0.2	0.3	0.6	0.8	0.6	-0.2
Illnesses of siblings	0.2	0.3	0.8	-0.5	-0.0	-0.9
Pulse rate	0.2	0.4	0.6	-0.2	-0.8	-0.7
Noisy workplace	0.2	0.3	0.7	0.4	0.1	0.8
Worry too long after embarrassment	0.2	0.4	1.1	0.3	1.0	0.2
Health satisfaction	0.2	0.2	0.4	0.1	-0.6	-0.6
Pulse rate, automated reading	0.2	0.7	1.0	-0.5	-0.9	-1.0
Overall health rating	0.2	0.5	0.7	0.8	0.8	-0.5
Chest pain or discomfort	0.2	0.3	0.5	0.7	0.2	-0.7
Mood swings	0.2	0.3	0.6	0.1	0.8	-0.5
Friendships satisfaction	0.2	0.2	0.4	-0.3	-0.6	0.4
High cholesterol (Self-reported)	0.2	0.4	1.2	1.1	0.1	0.3
Depressed Affect (Nagel 2018)	0.1	0.2	0.3	0.6	0.1	0.5
Alzheimer’s Disease (including proxy)	0.1	0.2	0.3	0.5	0.4	0.4
Crohns Disease (2017)	0.1	0.2	0.4	-0.3	0.2	0.6
Irritable Bowel Disease (IBD)	0.1	0.3	0.5	-0.4	0.7	0.4
Reaction Time	0.1	0.2	0.4	0.1	-0.6	0.6
Blood Eosinophil Count	0.1	0.9	1.5	1.0	-1.2	0.3
Smoking Status	0.1	0.2	0.2	0.5	-0.5	0.2
Neuroticism	0.1	0.3	0.7	0.8	0.5	-0.2
Hair Pigment	0.1	3.1	6.2	1.4	2.5	-1.0
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.2	0.2	-0.5	0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.4	-0.1	-0.4	0.6
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.4	0.1	-0.0	-0.7
Trunk fat mass	0.1	0.3	0.6	0.6	-0.7	-0.4
Hearing difficulty/problems with background noise	0.1	0.2	0.6	0.8	0.1	-0.2
Falls in the last year	0.1	0.1	0.1	0.3	0.1	-0.3
Medication: Cholesterol lowering	0.1	0.1	0.2	0.5	0.1	0.4
Arm fat mass (right)	0.1	0.3	0.5	-0.1	-0.7	-0.7
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.2	0.1	-0.5	0.4
Age at first live birth	0.1	0.2	0.3	-0.5	-0.3	0.5
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.7	-0.1	-0.1
Medication: Blood pressure	0.1	0.3	0.3	-0.6	0.5	-0.4
Whole body fat mass	0.1	0.4	0.6	-0.2	-0.8	-0.7
Leg fat mass (right)	0.1	0.3	0.7	0.0	-0.8	-0.5
Alcohol intake frequency.	0.1	0.3	0.8	0.1	0.5	0.9
Family relationship satisfaction	0.1	0.1	0.1	0.3	-0.3	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.3	-0.0	-0.6	-0.2
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.1	-0.2	-0.4
Arm fat mass (left)	0.1	0.4	0.9	-0.4	-0.5	-0.9
Miserableness	0.1	0.1	0.2	0.2	0.5	-0.1
Mother’s age at death	0.1	0.1	0.2	0.3	0.5	-0.3
Pack years of smoking	0.1	0.2	0.3	0.0	-0.5	0.6
Leg fat mass (left)	0.1	0.2	0.5	-0.1	-0.7	-0.4
Schizophrenia (2014)	0.0	0.0	0.1	-0.3	0.0	-0.2
Tanning	0.0	0.6	1.5	-1.2	0.4	-0.3
Systolic blood pressure, automated reading	0.0	0.1	0.1	0.3	0.2	0.3
Stomach or abdominal pain in last month	0.0	0.0	0.0	-0.0	-0.1	0.1
Pain all over the body in last month	0.0	0.0	0.1	-0.3	0.1	-0.1
Fluid intelligence score	0.0	0.0	0.1	-0.3	0.0	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.1	0.2	0.2	-0.2
Depression (self-reported)	0.0	0.0	0.1	0.3	-0.0	-0.0
Qualifications: College or University degree	0.0	0.1	0.3	0.1	-0.5	0.2
Medication: Ibuprofen	0.0	0.0	0.1	-0.0	0.1	0.3

Hub : Genes

C1orf105

Models

Trait associations