Hub : Genes

DNM3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.3470	0.0900	1.3e-04	0.256	NA	0.277	NA	0.263	3.0e-07	NA	8.3e-08	NA	1.9e-07
2	GTEx	Brain Cerebellum	0.2640	0.0840	1.2e-03	0.289	NA	0.249	NA	0.274	3.4e-09	NA	5.7e-08	NA	1.0e-08
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1720	0.0540	3.2e-04	0.122	NA	0.089	NA	0.104	3.5e-07	NA	1.4e-05	NA	2.6e-06
4	GTEx	Skin Sun Exposed Lower leg	0.1320	0.0390	9.4e-05	0.086	NA	0.076	NA	0.074	1.4e-07	NA	7.7e-07	NA	9.6e-07
5	YFS	Blood	0.0333	0.0133	1.8e-03	0.004	0.010	0.010	0.013	0.007	1.3e-02	1.7e-04	2.6e-04	4e-05	1.7e-03
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2430	0.0660	2.2e-07	0.152	0.147	0.177	NA	0.172	4.7e-09	9.1e-09	2.4e-10	NA	4.4e-10
7	TCGA	Prostate Adenocarcinoma	0.0488	0.0201	2.6e-04	0.029	0.034	0.037	NA	0.034	4.4e-04	1.7e-04	8.8e-05	NA	1.7e-04
8	TCGA	Thyroid Carcinoma	0.1330	0.0370	3.8e-09	0.079	0.097	0.101	NA	0.080	4.3e-08	1.0e-09	4.9e-10	NA	3.5e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.5	0.7	1.7	0.8	1.0	-0.7	-0.5	1.3	0.2	-1.3	0.5
Bipolar Disorder or Schizophrenia	0.3	0.8	2.2	-1.0	-0.4	-1.5	-1.4	0.9	-0.0	0.0	0.0
Depressed Affect (Nagel 2018)	2.3	4.9	8.4	-2.5	-2.5	-2.8	-2.9	-1.5	1.9	1.9	0.9
Depression (Nagel 2018)	0.8	1.2	3.2	-0.5	-0.9	-1.8	-1.7	-1.6	0.1	-0.4	-0.4
Intelligence (Savage-Jansen 2018)	2.0	6.0	23.5	0.9	0.7	4.7	4.8	0.7	0.1	0.5	0.5
Neuroticism (Nagel 2018)	2.9	6.8	14.4	-2.4	-2.5	-3.5	-3.8	-1.5	3.1	1.2	1.6
Schizophrenia (2018)	0.7	1.4	4.3	-2.1	-1.4	-1.4	-1.5	0.1	-0.2	1.1	-0.3
Schizophrenia vs Biploar Disorder	0.6	0.7	1.4	-1.0	-0.2	-1.2	-1.1	-1.1	-0.4	-0.0	-0.9
Worry (Nagel 2018)	2.9	6.2	12.0	-2.6	-2.7	-3.1	-3.5	-0.9	2.7	1.6	1.8
Alzheimer’s Disease (in mother)	1.0	1.2	3.5	1.9	1.2	1.4	1.0	-0.4	0.3	-0.8	0.7
Alzheimer’s Disease (in father)	0.1	0.2	0.3	-0.3	0.2	0.5	0.4	-0.5	0.0	-0.5	-0.5
Alzheimer’s Disease (including proxy)	0.9	1.2	2.6	1.3	1.1	1.6	1.3	-0.9	0.2	-1.4	-0.0
Crohns Disease (2017)	0.3	0.7	3.0	0.5	0.0	1.0	0.5	-0.2	1.7	0.0	1.1
Irritable Bowel Disease (IBD)	0.3	0.8	3.2	-0.4	-1.0	0.2	-0.1	0.4	1.8	1.2	0.7
Ulcerative Colitis (UC)	0.7	1.4	3.2	-1.2	-1.8	-0.5	-0.6	0.9	1.3	1.7	0.4
Major Depression (MDD)	0.7	0.8	2.9	-0.6	-1.7	-0.4	-0.2	-1.0	0.3	1.4	0.4
Reaction Time	0.3	0.6	2.4	0.5	-0.0	-0.5	-0.3	-0.3	1.6	-0.9	0.9
Verbal and Numeric Reasoning (VNR)	2.6	6.2	25.1	0.7	0.4	4.8	5.0	0.5	-0.3	0.8	0.6
Breast Cancer	0.7	1.6	4.5	-0.8	-1.6	0.6	0.1	-0.6	1.7	2.1	1.2
Ovarian Cancer	2.5	3.3	6.6	-1.8	-1.3	-2.6	-2.5	2.0	1.0	0.8	1.7
Prostate Cancer	0.8	1.1	2.8	-0.0	-0.1	1.4	1.4	1.7	-0.2	0.8	1.0
Age at First Birth	0.2	0.3	0.9	-0.2	0.4	-0.7	-0.9	0.5	0.4	-0.6	-0.3
Bipolar Disorder (2011)	0.2	0.2	0.6	-0.4	0.5	-0.3	-0.2	-0.4	-0.0	-0.8	-0.2
Body Mass Index (BMI) (2010)	0.7	1.0	2.2	0.9	1.3	1.3	1.5	-0.0	-1.2	-0.3	0.2
Coronary Artery Disease (CAD)	0.4	0.5	1.6	-0.4	-0.4	-0.3	-0.2	-1.3	-0.2	1.3	-0.5
Crohns Disease (2012)	0.1	0.2	0.6	-0.3	-0.4	-0.1	-0.5	-0.0	0.8	0.3	0.8
Mean Putamen Volume	0.8	0.9	3.8	0.3	0.0	-2.0	-1.7	0.5	0.1	-0.4	-0.3
Fasting Glucose	0.4	0.5	2.5	0.2	0.3	-0.3	-0.4	-0.1	-1.6	0.3	-0.9
HbA1C	1.6	1.8	6.4	-0.6	-1.1	-0.1	-0.2	0.6	1.4	1.9	2.5
HDL Cholesterol	0.9	1.5	2.3	0.9	1.2	1.4	1.4	1.4	-1.1	-1.5	0.1
LDL Cholesterol	0.4	0.6	1.3	0.9	0.7	1.1	1.1	0.8	0.4	0.6	0.0
Lupus	0.6	0.9	2.6	-0.5	-0.6	-0.6	-0.8	-0.9	-1.5	-0.1	-1.6
Neuroticism (2016)	2.3	3.4	6.0	-2.0	-2.4	-1.6	-2.0	-1.0	2.3	1.5	1.3
Primary Biliary Cirrhosis	1.1	1.6	2.5	1.4	1.2	1.4	1.6	0.8	-1.1	-1.5	-0.8
Rheumatoid Arthritis	0.8	1.1	2.9	1.4	1.3	-1.0	-0.5	0.3	-0.4	-1.7	-0.7
Schizophrenia (2014)	0.5	1.1	3.3	-1.1	-0.5	-1.8	-1.8	0.6	-0.1	-0.2	-0.8
Triglycerides	0.5	0.9	2.2	-0.5	-0.9	-0.7	-0.6	-1.0	1.5	1.3	0.7
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.6	0.2	-0.2	0.1	0.5	-0.5	0.0	0.8	-0.1
Ulcerative Colitis	0.2	0.2	1.4	0.0	-0.1	-0.4	-0.2	1.2	-0.2	0.2	-0.4
Blood Eosinophil Count	0.1	0.9	2.9	0.0	-0.3	0.9	1.7	1.0	-0.9	0.6	-1.1
Blood Platelet Count	8.2	95.3	231.0	15.2	14.8	9.6	9.4	5.1	-3.2	-9.7	1.5
Blood Red Count	0.7	7.0	15.4	-1.6	-2.1	-3.5	-3.8	-3.9	1.5	2.1	-0.2
Blood White Count	0.0	0.2	0.6	0.1	0.2	-0.2	-0.1	-0.8	-0.5	0.6	-0.4
Heel T-Score	1.9	14.9	46.2	-0.1	1.1	-1.8	-1.3	-4.7	-4.7	-4.8	-6.8
BMI	0.8	4.5	11.5	-2.2	-2.7	-0.3	-0.6	0.5	2.5	2.3	3.4
Height	0.9	16.4	39.6	-3.9	-5.0	3.8	3.2	-0.0	-4.5	2.3	-6.3
Waist Hip Ratio (WHR)	0.5	2.3	7.8	-0.3	-1.7	-0.7	-1.2	-0.8	2.8	1.8	1.3
Systolic Blood Pressure	0.5	2.4	6.1	1.9	0.4	2.5	2.3	0.7	-1.3	0.5	-1.2
Smoking Status	1.8	4.3	7.9	-2.8	-2.3	-1.1	-1.3	-1.7	2.2	2.7	1.9
Allergy or Eczema	1.1	3.0	5.8	1.6	1.6	1.6	1.9	-1.6	-1.7	-1.1	-2.4
Cardiovascular Disease	0.3	1.0	2.7	-0.1	-1.4	1.6	1.1	-0.8	-0.0	1.2	-0.1
Hypothyroidism (self reported)	0.4	0.8	3.0	0.2	-0.1	-1.5	-1.7	0.0	-0.1	-1.1	-0.1
Respiratory disease	0.2	0.3	1.1	0.6	-0.5	0.7	0.3	-1.1	0.1	0.7	-0.2
Type 2 Diabetes (T2D) (2018)	1.4	2.6	6.9	2.3	1.6	0.8	0.6	-0.0	-1.2	-2.6	-1.8
Lung FEV1/FVC ratio	0.9	4.6	8.5	-1.8	-1.9	2.3	1.5	0.2	2.9	2.9	2.2
Lung FVC	0.7	3.4	15.5	0.6	1.4	0.0	0.6	-3.9	-1.6	-2.2	-1.2
Neuroticism	4.5	10.8	24.4	-3.4	-3.2	-4.6	-4.9	-1.1	3.7	1.1	1.7
Chronotype (morning person)	1.5	3.4	7.9	-1.1	-1.4	-0.6	-1.4	1.4	2.8	2.3	2.6
Hair Pigment	0.0	1.2	3.0	1.5	0.7	-1.7	-1.4	-0.9	0.5	-0.6	-0.8
Tanning	0.1	1.6	2.7	-1.4	-1.6	-0.9	-1.1	-0.9	1.1	1.4	1.6
Hand grip strength (left)	0.1	0.3	0.7	0.4	-0.3	0.6	0.9	0.7	-0.4	-0.3	-0.5
Number of treatments/medications taken	0.3	0.5	2.9	0.9	0.5	0.5	0.1	-1.7	-0.0	-0.2	-0.4
Average weekly spirits intake	1.3	1.6	3.0	-1.4	-1.7	-0.8	-1.2	-1.0	1.7	1.1	0.9
Sensitivity / hurt feelings	2.7	4.6	11.7	-1.1	-1.7	-3.1	-3.2	-0.7	3.4	0.8	0.3
Frequency of depressed mood in last 2 weeks	0.8	1.1	1.6	-1.3	-1.2	-1.0	-1.1	-1.2	1.2	0.4	0.4
Hearing difficulty/problems: Yes	0.4	0.6	1.8	0.5	0.2	-0.9	-1.3	-0.0	-0.3	-1.1	-0.6
Relative age of first facial hair	0.5	1.1	3.5	1.2	1.0	1.0	0.6	1.9	0.4	-1.1	-0.1
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	4.7	0.6	0.4	1.2	1.0	-0.5	-2.2	-0.6	-0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.4	0.5	0.0	-0.3	-0.2	0.3	-1.2	0.3	-0.3
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	-0.6	-0.4	-0.5	-0.8	-0.0	-0.3	-0.5	-0.4
Systolic blood pressure, automated reading	0.1	0.4	1.6	0.3	-0.0	0.7	0.2	0.2	-1.3	0.0	-1.0
Eye problems/disorders: Diabetes related eye disease	3.3	3.6	7.8	2.7	2.7	0.3	0.7	-1.8	-0.8	-2.8	-1.5
Angina	0.3	0.4	2.4	0.2	0.0	0.4	-0.4	-1.6	0.2	0.0	0.2
Medication for hormone replacement therapy	0.3	0.3	1.5	-0.4	-0.4	-0.5	-0.1	-0.5	-1.2	0.2	-0.3
Vitamin and mineral supplements	0.3	0.5	1.2	1.1	0.4	0.6	1.1	0.7	0.3	0.0	0.4
Supplements: Zinc	3.3	3.6	8.8	-2.3	-2.4	0.1	-0.4	1.0	2.2	3.0	1.8
Medication: Co-codamol	1.0	1.1	3.3	-0.4	-0.6	-1.6	-1.8	-1.4	0.7	-0.5	0.3
Medication: Metformin	1.1	1.5	3.0	1.7	1.1	1.4	1.1	-0.4	-0.9	-1.2	-1.6
Diabetes (father)	0.6	0.8	1.9	0.9	0.8	-0.9	-0.5	-0.3	-0.9	-0.9	-1.4
Diabetes (mother)	0.3	0.4	1.0	0.6	0.5	-0.7	-0.5	0.2	1.0	-1.0	0.2
Severe depression (siblings)	0.7	0.8	2.2	-0.7	-1.0	-1.0	-1.2	1.5	0.1	0.8	0.3
Pack years adult smoking proportion	0.4	0.6	1.8	-0.8	-1.3	-0.1	-0.8	-0.5	0.4	1.0	0.2
Impedance of leg (right)	0.4	1.9	9.9	0.2	-0.1	-1.1	-1.2	-0.9	-1.0	-0.7	-3.1
Leg fat-free mass (left)	0.4	2.3	6.9	-2.5	-2.6	1.2	1.0	0.3	0.6	1.6	0.5
Trunk fat percentage	0.7	2.6	5.9	-2.1	-2.4	-1.0	-1.2	0.1	1.5	1.8	1.7
Hand grip strength (right)	0.2	0.6	2.3	0.6	-0.2	1.3	1.5	0.3	-0.3	-0.1	-0.2
Townsend deprivation index at recruitment	1.0	1.5	2.8	-1.1	-1.7	-0.4	-0.9	-1.1	1.3	1.2	1.6
Current tobacco smoking	1.1	1.8	3.6	-1.7	-1.2	-0.0	-0.2	-0.9	1.9	1.6	1.8
Average weekly fortified wine intake	0.6	0.7	1.6	0.5	0.7	-0.4	-0.7	0.9	-1.3	-1.2	-0.8
Maternal smoking around birth	1.1	1.5	5.2	-0.5	-0.6	-2.3	-2.2	-0.1	0.7	-0.0	0.9
Fed-up feelings	3.7	6.8	11.4	-3.4	-3.4	-2.1	-2.4	-1.2	3.4	2.5	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	4.7	-1.6	-1.9	-2.1	-2.2	-1.3	0.2	0.8	-1.0
Relative age voice broke	0.7	1.0	2.5	1.2	1.6	1.0	1.1	0.9	0.1	-1.0	0.1
Taking other prescription medications	0.7	1.1	2.2	1.4	0.8	-0.1	-0.1	-1.5	-0.9	-1.2	-1.3
Age when periods started (menarche)	0.6	1.4	4.5	1.0	0.6	2.1	2.1	-0.4	-0.5	-0.1	-0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	-0.2	0.1	0.1	-0.4	-0.2	-0.0	-0.4	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	4.8	-0.8	-0.2	-1.9	-1.5	-0.8	-1.1	-0.9	-2.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.9	-0.2	0.4	-0.6	-0.8	-0.8	1.0	-0.3	0.5
Qualifications: CSEs or equivalent	0.5	0.7	2.4	-0.0	-0.2	-0.3	-0.8	0.6	1.5	0.3	1.4
Serious illness, injury or assault to yourself	0.4	0.4	1.4	-0.9	-0.8	-0.2	-0.5	-1.2	-0.3	0.2	0.2
High blood pressure	0.2	0.5	1.5	0.1	-0.6	0.6	0.3	-1.2	-0.8	0.7	-0.3
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.2	0.7	0.6	1.2	1.4	-0.4	-1.4	-0.4	-2.0
Multivitamins +/- minerals	1.0	1.3	2.7	-1.6	-1.4	-1.2	-1.7	-0.3	-0.4	0.9	-0.7
Stomach or abdominal pain in last month	0.2	0.3	1.1	-0.4	-0.5	-0.5	-0.3	0.2	1.0	0.2	0.5
Supplements: Glucosamine	0.1	0.1	0.7	-0.3	-0.1	-0.2	-0.3	-0.8	-0.2	0.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.3	0.8	-0.1	1.0	0.8	-0.2	-1.1	0.0	-0.5
Medication: Atenolol	0.5	0.6	1.4	0.5	-0.3	1.1	0.6	1.1	0.1	1.2	0.5
Medication: Levothyroxine sodium	1.1	1.8	5.2	1.6	1.6	-0.7	-1.2	0.2	-0.8	-2.3	-1.3
Sitting height	0.6	4.0	10.6	-2.5	-3.2	1.5	1.0	0.8	-1.3	1.4	-2.7
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	-0.1	0.2	0.4	-0.3	0.5	0.2	-0.4	0.7
High blood pressure (mother)	0.5	0.6	1.3	1.1	0.7	0.3	0.5	-0.2	-0.8	-1.1	-1.1
Body mass index (BMI)	0.9	3.7	8.0	-2.1	-2.2	-1.1	-1.4	-0.4	2.3	2.1	2.8
Impedance of leg (left)	0.4	1.8	8.0	0.2	-0.1	-1.5	-1.5	-0.5	-1.0	-0.6	-2.8
Leg predicted mass (left)	0.5	2.4	7.2	-2.5	-2.7	1.2	1.0	0.3	0.6	1.6	0.5
Trunk fat mass	0.7	3.1	9.0	-2.6	-3.0	-0.6	-0.9	-0.1	1.3	2.1	1.3
Waist circumference	1.2	4.3	8.3	-2.5	-2.9	-0.9	-1.1	-0.7	2.4	2.4	2.3
Number of incorrect matches in round	0.4	0.7	2.4	0.4	0.4	-1.4	-0.5	-0.4	-0.6	-1.5	0.5
Past tobacco smoking	0.7	1.2	4.9	0.6	0.4	1.4	1.2	2.2	-0.7	-0.5	-0.3
Alcohol usually taken with meals	1.2	1.9	3.2	1.2	1.8	0.8	1.3	1.4	-1.6	-1.5	-1.4
Nervous feelings	1.3	2.5	5.8	-1.2	-1.2	-2.2	-2.4	-1.7	1.8	0.2	0.1
Frequency of tenseness / restlessness in last 2 weeks	3.3	5.2	14.3	-2.7	-2.5	-3.3	-3.8	-0.9	0.4	0.8	-0.8
Hearing difficulty/problems with background noise	0.6	1.0	2.6	-1.1	-1.3	-1.1	-1.6	-0.0	1.2	0.1	0.3
Hair/balding pattern: Pattern 2	0.6	0.7	2.7	0.8	1.2	-0.8	-0.4	0.0	-0.2	-1.6	0.4
Had menopause	0.2	0.3	1.0	-1.0	-0.4	-0.3	-0.7	0.3	0.2	0.2	0.7
Had other major operations	0.1	0.2	0.5	-0.2	-0.5	-0.7	-0.4	-0.4	-0.4	0.0	-0.3
Forced vital capacity (FVC)	0.7	2.7	8.1	-0.8	-0.6	1.3	1.7	-1.7	-2.1	-0.6	-2.9
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.2	5.1	-0.5	0.1	-1.9	-1.5	-1.5	-1.4	-1.4	-2.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	4.7	0.4	0.1	-0.2	-0.1	-2.2	-1.6	-0.0	-1.8
Qualifications: None of the above	1.3	2.8	7.7	-1.3	-1.3	-1.1	-1.6	0.4	2.8	1.1	2.4
Financial difficulties in last 2 years	1.4	1.9	6.1	-2.1	-2.5	-0.2	-0.6	-1.0	0.7	1.6	0.8
Mouth/teeth dental problems	1.4	2.1	5.5	-0.7	-1.4	-0.2	-0.7	1.9	2.4	1.2	1.7
Heart attack	0.6	0.8	2.1	-0.3	-1.2	1.1	0.8	0.4	0.9	1.4	0.2
Allergy	0.2	0.4	0.8	-0.4	-0.2	-0.9	-0.8	-0.2	0.7	-0.0	0.8
Pain all over the body in last month	4.2	4.5	10.1	-2.3	-2.5	1.3	0.8	-0.4	2.1	2.8	3.2
Diabetes (self-reported)	2.3	3.6	6.9	2.5	2.0	0.8	0.7	-1.2	-1.8	-2.6	-2.4
Hayfever/allergic rhinitis (self-reported)	2.6	3.4	9.9	1.4	1.5	2.4	3.1	-0.9	-1.8	-1.2	-1.5
Medication: Ramipril	1.3	1.7	4.0	1.7	1.2	1.9	2.0	0.4	-0.7	-0.8	-0.0
Medication: Simvastatin	1.1	1.6	3.5	1.6	1.3	1.0	0.6	-1.9	-1.1	-0.8	-1.4
Fluid intelligence score	2.4	5.0	18.4	0.7	0.6	4.3	4.2	0.9	0.4	0.8	1.2
Illnesses of siblings	0.4	0.6	1.4	0.7	1.2	-0.3	0.1	-0.1	-1.0	-1.1	-0.7
Neuroticism score	5.5	11.4	21.6	-3.8	-3.7	-4.2	-4.6	-1.1	4.1	1.9	1.7
Weight	0.7	3.3	10.6	-2.9	-3.3	0.4	-0.0	-0.2	1.1	2.3	0.9
Impedance of arm (right)	0.5	2.1	3.8	1.5	1.5	0.8	1.2	-0.1	-2.0	-1.6	-2.0
Arm fat percentage (right)	0.8	3.0	6.7	-1.8	-2.1	-1.0	-1.2	-0.1	1.8	2.0	2.6
Trunk fat-free mass	0.4	2.5	7.7	-2.6	-2.8	1.3	0.8	0.3	0.1	1.6	-0.9
Hip circumference	0.5	2.0	6.8	-2.6	-2.2	0.3	0.2	-0.5	0.4	1.6	1.1
Time employed in main current job	0.8	0.9	3.3	0.7	0.3	0.8	0.7	-0.7	1.8	0.4	1.3
Alcohol intake versus 10 years previously	1.1	1.7	6.4	-0.8	-0.8	-1.0	-0.9	-2.5	-0.8	1.2	-1.4
Father’s age at death	0.7	0.9	1.5	0.7	1.1	0.7	1.2	-0.6	-1.2	-1.2	-0.7
Worrier / anxious feelings	4.1	7.7	17.4	-2.8	-3.1	-4.2	-4.1	-0.4	2.3	1.8	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.8	-0.8	-0.9	-1.2	-1.3	-0.9	0.6	0.2	0.1
Falls in the last year	4.1	5.6	10.0	-1.9	-2.5	1.7	0.9	2.3	2.6	3.2	3.0
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	-0.3	-0.7	0.1	-0.4	-0.7	-0.6	1.2	-0.2
Number of live births	1.7	2.4	6.3	1.2	1.5	-0.5	-0.3	-2.5	-1.2	-1.9	-2.0
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	6.1	-1.0	-1.0	1.5	1.8	-1.9	-1.5	-0.0	-2.5
Pulse rate	1.8	3.1	6.2	1.8	2.5	1.5	1.8	-1.9	-1.5	-1.7	-1.1
Happiness	1.9	2.3	3.5	-1.8	-1.9	-1.8	-1.6	-0.2	1.4	1.6	1.1
Noisy workplace	1.6	2.0	6.9	-1.0	-0.7	-2.6	-2.3	-0.0	1.3	-0.0	0.6
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.4	-0.7	-0.2	1.7	1.8	0.1	-1.3	0.5	-0.8
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	2.5	0.5	1.0	0.0	0.3	-1.6	-1.1	-1.6	-1.5
Mouth/teeth dental problems: Dentures	4.1	6.9	19.0	1.6	2.3	-0.2	0.3	-4.4	-3.3	-2.3	-3.4
Asthma	0.3	0.6	1.8	0.3	-0.6	1.3	0.9	-0.6	0.6	0.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.7	0.1	0.1	0.3	0.0	-0.6	0.6	-0.8	-0.0
Medication: Cholesterol lowering	0.1	0.2	0.4	-0.2	-0.3	-0.1	-0.5	-0.4	0.7	0.6	0.5
Depression (self-reported)	3.8	4.5	10.4	-3.0	-3.2	-1.6	-1.6	0.9	1.9	2.6	0.8
Medication: Lansoprazole	2.2	2.5	6.0	1.9	2.0	1.3	1.5	-2.5	-0.7	-1.2	0.2
Prospective memory result	1.8	2.2	6.1	-1.8	-1.0	-2.5	-2.4	0.4	-0.2	0.0	0.9
Lung cancer (father)	0.4	0.5	0.9	0.2	0.3	-0.9	-0.8	0.2	-0.8	-0.9	-0.9
Illnesses of mother	1.0	1.3	3.9	-1.7	-1.6	-0.1	-0.3	-0.8	0.1	2.0	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	5.9	-0.7	-0.6	1.3	1.6	-1.5	-1.4	-0.7	-2.4
Pulse wave Arterial Stiffness index	0.2	0.3	1.1	0.5	0.3	1.1	0.6	-0.5	-0.3	-0.1	0.3
Impedance of arm (left)	0.5	2.3	3.3	1.4	1.5	1.4	1.7	-0.1	-1.8	-1.5	-1.8
Arm fat mass (right)	0.7	2.7	6.5	-2.3	-2.6	-0.6	-0.9	-0.4	1.4	2.0	1.8
Trunk predicted mass	0.4	2.5	7.7	-2.6	-2.8	1.3	0.8	0.3	-0.0	1.5	-0.9
Standing height	0.6	6.3	15.7	-2.2	-2.7	3.0	2.6	0.6	-2.4	0.7	-4.0
Length of working week for main job	0.9	1.0	1.7	-1.3	-0.9	-1.3	-1.2	0.2	0.8	1.1	0.9
Exposure to tobacco smoke at home	0.1	0.1	0.4	-0.1	-0.1	0.0	-0.4	-0.3	0.6	0.5	0.0
Breastfed as a baby	0.6	0.7	2.0	-0.5	-0.5	0.8	1.0	-0.4	-1.4	0.9	-0.6
Tense / ‘highly strung’	3.7	6.1	12.3	-3.2	-2.9	-2.7	-3.5	-1.4	2.3	1.6	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.6	8.2	-1.2	-2.1	-1.5	-1.2	-0.2	1.3	2.9	1.1
Hair/balding pattern: Pattern 4	0.5	1.2	6.0	-0.0	-0.1	0.3	-0.1	-1.1	2.5	0.1	1.6
Birth weight of first child	2.1	3.8	8.9	-2.6	-3.0	-0.3	-0.4	2.1	1.0	2.5	1.6
Peak expiratory flow (PEF)	0.9	2.2	5.2	-1.6	-2.2	0.8	0.6	-1.9	0.3	2.3	-0.5
Pulse wave reflection index	0.5	0.6	1.6	-0.3	-1.2	-0.1	-0.2	-0.2	1.3	1.0	0.5
Ever highly irritable/argumentative for 2 days	1.4	1.7	5.3	-2.1	-2.3	-1.1	-1.0	-0.3	-0.3	0.9	-0.5
Loud music exposure frequency	0.2	0.2	0.8	-0.0	-0.3	0.5	0.1	-0.9	0.5	-0.7	-0.2
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	5.3	-2.0	-1.6	1.5	1.3	0.7	0.4	2.3	0.7
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.5	-0.9	-0.4	-0.9	-1.0	1.6	0.5	0.1	0.7
Blood clot in the leg (DVT)	2.3	3.0	5.7	-1.6	-1.8	-1.8	-2.1	0.6	1.4	1.6	2.4
Medication: Paracetamol	0.4	0.7	1.7	-0.8	-0.8	-0.8	-1.0	0.1	1.3	0.6	0.7
Headache pain in last month	0.2	0.4	2.1	0.3	0.2	-0.3	-0.3	0.7	1.4	0.4	0.6
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.2	0.8	1.2	0.2	0.7	-0.3	-1.0	-1.5	-1.3
Glaucoma (self-reported)	0.4	0.4	1.0	0.6	0.9	1.0	0.8	-0.0	-0.4	-0.2	0.6
Gout (self-reported)	1.4	1.9	9.7	0.1	0.1	1.6	1.3	3.1	0.1	0.9	0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.8	0.5	0.5	-0.9	-1.4	0.8	0.4	-1.1	-0.1
Medication: Amlodipine	0.6	0.9	2.8	1.4	0.4	0.3	0.1	0.3	1.7	-0.3	1.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.6	0.6	0.3	-0.3	-0.2	-0.0	0.8	-0.3	0.4
Birth weight	0.3	0.6	1.3	-0.9	-1.0	-0.2	-0.4	0.8	1.1	0.8	0.1
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.1	0.9	0.6	-0.6	0.1	-0.3	-1.0	-0.4	-0.8
High blood pressure (siblings)	0.3	0.5	1.1	0.1	-0.4	1.0	0.8	-0.9	-0.4	-0.0	-0.9
Forced vital capacity (FVC), Best measure	0.8	3.1	9.9	-0.1	0.3	1.1	1.6	-1.8	-2.2	-1.6	-3.1
Body fat percentage	0.8	3.2	6.1	-2.1	-2.5	-1.3	-1.6	-0.1	1.8	1.9	2.0
Leg fat percentage (right)	0.8	2.9	4.9	-1.9	-2.2	-1.7	-2.0	-0.9	1.6	1.7	1.3
Arm fat-free mass (right)	0.5	2.5	9.2	-2.9	-3.0	0.2	-0.4	0.3	0.7	1.4	-0.3
Exposure to tobacco smoke outside home	1.2	1.5	6.4	0.2	-0.5	-0.7	-0.6	-1.0	2.5	0.8	1.8
Comparative body size at age 10	1.7	4.6	8.7	-1.8	-1.7	-2.7	-2.4	1.4	3.0	0.8	2.5
Number of full brothers	0.8	1.0	3.1	-0.2	-0.6	-1.6	-1.8	0.8	1.1	0.4	0.4
Worry too long after embarrassment	1.3	2.2	8.8	-1.1	-1.3	-1.2	-1.4	-0.3	3.0	-0.0	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.9	-0.9	-1.4	-1.2	-1.4	0.4	0.0	0.8	-0.7
Wheeze or whistling in the chest in last year	2.6	4.7	9.4	-3.0	-3.1	-1.6	-2.2	-0.3	1.9	2.5	1.2
Number of children fathered	0.3	0.3	0.9	-0.1	0.1	0.5	0.9	-0.1	-0.6	0.5	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.5	-0.7	-0.7	-0.9	-0.3	-0.3	1.2	0.7	0.6
Age at first live birth	0.4	0.6	2.2	0.2	-0.1	1.3	1.5	1.0	-0.2	0.4	-0.2
Pulse wave peak to peak time	0.2	0.3	0.7	-0.7	-0.5	-0.8	-0.4	0.6	0.1	0.2	-0.4
Health satisfaction	0.7	0.9	1.7	-1.3	-1.3	0.9	0.1	0.5	0.6	1.3	0.5
Shortness of breath walking on level ground	0.2	0.3	1.1	0.1	-0.1	0.1	-0.2	-1.1	-0.3	-0.3	-0.9
Qualifications: College or University degree	2.6	8.1	24.6	1.5	2.6	1.0	1.9	-0.5	-4.3	-2.8	-5.0
Eye problems/disorders: None of the above	2.9	3.3	8.4	-1.5	-2.0	-1.3	-1.5	0.4	2.9	1.4	2.4
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.9	0.5	0.3	1.7	1.5	0.9	0.6	0.5	0.9
Emphysema/chronic bronchitis	1.1	1.2	3.0	1.2	0.8	1.5	1.7	-0.3	-0.8	-0.9	-1.0
Medication for pain relief, constipation, heartburn	0.4	0.6	1.4	0.8	0.5	0.8	1.2	0.7	-0.9	-0.8	-0.6
Neck or shoulder pain in last month	0.7	1.0	3.6	-0.9	-0.6	-1.9	-1.8	0.4	0.2	-0.0	0.1
Medication: Blood pressure	0.6	1.1	2.8	-1.0	-1.4	0.3	0.1	1.0	0.4	1.7	1.4
Angina (self-reported)	0.2	0.3	1.5	0.3	0.3	0.4	-0.3	-1.2	0.1	-0.3	0.1
Migraine (self-reported)	1.6	1.9	6.0	0.1	-0.8	1.1	1.4	1.1	1.3	1.7	2.4
Medication: Ibuprofen	0.3	0.4	1.3	0.2	0.4	-0.5	-0.9	-0.2	0.5	-1.1	-0.3
Medication: Allopurinol	1.9	2.6	8.3	0.8	0.5	2.4	2.1	2.9	0.6	0.2	1.0
Medication: Omeprazole	0.4	0.4	2.1	0.3	-0.7	-0.3	-0.2	-1.4	0.4	0.7	0.1
Medication: Seretide 50 evohaler	0.8	0.9	2.2	-0.4	-0.2	-1.4	-1.5	-1.1	0.1	-0.6	-0.9
Mean time to correctly identify matches	0.4	0.7	1.8	0.7	0.6	-0.3	-0.4	-0.9	1.1	-1.4	0.8
Heart disease (mother)	0.6	0.7	1.5	1.2	1.2	0.4	0.3	-0.4	-1.0	-1.0	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.6	-0.8	-1.0	-1.2	-1.1	-0.1	0.7	0.6	1.0
Whole body fat mass	0.9	3.6	9.2	-2.7	-3.0	-0.9	-1.3	0.1	1.5	2.1	1.6
Leg fat mass (right)	1.0	3.9	9.2	-2.8	-3.0	-1.4	-1.8	-0.4	1.7	2.1	1.3
Arm predicted mass (right)	0.5	2.5	9.4	-2.9	-3.1	0.4	-0.1	0.2	0.6	1.4	-0.4
Pulse rate, automated reading	0.2	0.6	3.1	-0.1	0.0	0.5	0.5	-1.8	-0.9	-0.1	-0.6
Alcohol intake frequency.	0.3	0.6	2.2	0.3	0.4	-0.9	-0.5	-0.7	-1.5	-0.7	-0.5
Comparative height size at age 10	1.8	9.9	31.5	-4.4	-5.6	2.2	1.4	1.8	1.0	4.1	0.6
Number of full sisters	0.5	0.6	1.3	1.0	0.7	-0.1	-0.7	-0.9	0.6	-1.1	0.7
Suffer from ‘nerves’	1.3	2.0	3.9	-1.5	-1.2	-1.8	-2.0	-0.5	1.8	0.3	1.2
Overall health rating	0.8	1.8	4.2	-1.5	-1.6	-0.3	-1.4	0.0	2.0	1.1	1.4
Chest pain or discomfort	0.3	0.5	1.3	-0.9	-1.1	0.1	-0.4	-1.1	0.6	0.5	0.2
Had major operations	0.6	0.6	1.4	-0.5	-0.8	-0.2	-0.1	1.1	0.8	1.0	1.2
Age at last live birth	0.1	0.1	0.3	-0.2	-0.2	-0.3	-0.0	0.5	-0.5	0.2	-0.1
Family relationship satisfaction	2.0	2.5	6.2	-1.0	-1.7	-1.5	-1.5	1.1	2.5	1.1	1.8
Leg pain on walking	0.3	0.4	0.7	-0.8	-0.5	-0.7	-0.7	-0.8	0.7	0.2	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	1.5	-0.5	-0.7	-1.0	-1.2	-1.1	0.6	0.8	1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.5	0.2	-0.1	1.2	1.0	-0.1	0.2	0.9	-0.1
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	6.3	2.5	2.5	2.1	2.2	0.9	-1.3	-1.1	-0.7
Medication: Aspirin	0.5	0.6	2.0	1.3	1.4	-0.0	-0.3	0.2	-1.0	-0.5	-0.5
Supplements: Vitamin C	0.5	0.6	1.5	-1.1	-0.6	0.5	0.4	-1.2	0.3	1.0	0.1
Knee pain experienced in last month	0.3	0.4	0.9	-0.9	-0.8	-0.6	-0.6	0.1	0.1	0.6	0.7
Hypertension (Self-reported)	0.3	0.7	2.2	0.7	-0.0	0.9	0.6	-1.5	-1.1	0.2	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	2.0	-0.8	-0.9	-0.8	-0.5	-1.4	0.2	0.2	-0.1
Illnesses of father: Heart disease	0.9	1.3	2.5	1.1	1.0	1.1	1.1	-1.6	-1.1	-0.9	-0.8
Illnesses of siblings: Diabetes	0.1	0.1	0.5	0.7	0.6	0.3	0.2	0.1	0.0	-0.4	0.1
Smoking status: Previous	0.7	1.0	4.5	-0.2	-0.1	-1.4	-1.1	-2.1	0.4	0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	1.7	-1.1	-1.2	1.3	1.2	-0.3	-0.6	0.8	-0.9
Whole body fat-free mass	0.4	2.4	7.7	-2.6	-2.8	1.2	0.7	0.5	0.4	1.5	-0.2
Leg fat-free mass (right)	0.4	1.9	5.2	-2.1	-2.3	1.4	1.1	0.6	0.5	1.3	0.5
Arm fat percentage (left)	0.6	2.5	6.1	-1.6	-1.8	-0.9	-1.1	-0.2	1.7	1.7	2.5
Average weekly red wine intake	0.1	0.1	0.4	-0.6	-0.6	-0.1	0.1	0.1	0.0	-0.2	0.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.8	0.0	0.0	-1.2	-1.3	-0.2	-0.7	-1.0	-0.4
Mood swings	2.4	4.4	8.7	-2.5	-2.2	-2.8	-2.9	-1.4	1.6	1.5	0.2
Loneliness, isolation	0.4	0.6	1.7	-0.6	-0.9	-0.8	-1.3	-0.8	0.6	0.5	-0.5
Long-standing illness, disability or infirmity	1.0	1.5	4.7	0.6	0.6	0.2	-0.2	-1.2	-2.2	-1.6	-1.6
Ever had bowel cancer screening	0.1	0.2	0.4	-0.2	-0.4	0.4	0.2	0.6	0.2	0.7	0.2
Diabetes diagnosed by doctor	2.6	4.3	10.2	3.2	2.5	0.9	0.8	-1.1	-1.6	-2.9	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.5	-0.6	-0.3	-0.3	-0.5	-1.2	0.5	-0.7	-0.3
Friendships satisfaction	0.8	1.0	2.1	-1.0	-1.3	0.0	-0.0	0.7	1.3	1.4	0.9
Qualifications: nursing, teaching	0.5	0.8	2.7	-0.1	0.4	0.9	1.0	1.6	-0.9	-0.4	-0.9
Commuting to job workplace: Walk	0.3	0.4	1.1	-0.1	0.3	-0.3	-0.0	-0.2	-1.0	-1.1	-0.9
Eye problems/disorders: Cataract	1.1	1.2	2.7	0.5	1.1	0.8	1.2	-0.6	-1.6	-0.8	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.8	-0.6	-0.5	-0.0	0.1	0.9	-0.3	0.6	-0.8
Medication for cholesterol	1.5	2.3	4.7	-1.8	-1.0	-0.7	-0.6	1.9	2.2	1.0	2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	4.0	-1.0	-1.2	-1.1	-0.6	0.3	1.2	1.6	2.0
Back pain experienced in last month	1.7	2.4	6.6	-2.4	-2.6	-0.2	-0.7	-1.4	0.9	1.9	0.7
Mineral and other dietary supplements	1.1	1.5	3.5	-1.5	-1.7	-0.7	-0.6	1.9	1.2	0.6	0.8
Breast cancer (self-reported)	0.5	0.6	1.6	0.6	-0.2	0.5	1.2	1.2	0.3	0.6	0.7
Asthma (self-reported)	0.3	0.7	1.7	0.1	-0.9	1.0	0.6	-0.4	0.9	1.3	0.6
Osteoporosis (self-reported)	0.8	1.0	2.5	1.6	1.0	1.2	1.1	-1.2	0.1	-0.4	0.3
Osteoarthritis (self-reported)	1.0	1.3	3.7	-1.9	-1.5	0.5	0.3	-1.4	0.5	1.4	0.6
Medication: Aspirin	0.5	0.7	2.5	1.4	1.6	0.5	0.0	-0.1	-0.8	-0.4	-0.3
Medication: Gliclazide	1.1	1.2	5.3	0.0	0.0	-0.6	-1.0	-2.3	0.4	-0.3	-1.7
Illnesses of father: None of the above (group 1)	1.2	1.4	2.8	-0.8	-1.0	-1.7	-1.0	0.7	1.3	1.1	1.7
Smoking status: Current	1.2	1.9	3.7	-1.9	-1.4	-0.1	-0.4	-0.9	1.7	1.9	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.6	8.5	1.0	1.7	0.5	1.4	-2.9	-1.0	-2.0	-1.2
Whole body water mass	0.4	2.4	7.7	-2.6	-2.8	1.2	0.8	0.3	0.3	1.5	-0.2
Leg predicted mass (right)	0.4	2.0	5.3	-2.1	-2.3	1.4	1.1	0.6	0.6	1.4	0.6
Arm fat mass (left)	0.6	2.4	5.5	-2.2	-2.4	-0.8	-1.0	-0.5	1.2	1.7	1.6
Number of self-reported non-cancer illnesses	0.7	1.1	2.0	-1.0	-1.4	1.1	0.7	-1.2	0.9	1.4	0.4
Average weekly champagne plus white wine intake	0.8	1.1	2.7	0.8	1.0	-1.2	-0.6	1.6	-1.1	-0.8	-0.9
Miserableness	2.5	4.4	8.8	-2.0	-2.1	-3.0	-2.9	-1.3	2.1	1.3	1.2
Guilty feelings	1.9	2.9	8.2	-1.4	-1.4	-2.7	-2.9	-1.8	0.8	0.2	0.2
Wears glasses or contact lenses	0.7	0.8	1.8	1.2	1.3	-0.3	0.2	0.2	-1.2	-0.8	-0.9
Ever taken oral contraceptive pill	0.6	0.7	2.0	0.1	1.1	-1.0	-1.0	-0.2	-0.1	-1.4	-0.3
Hearing aid user	2.9	3.3	6.6	2.4	2.6	0.2	0.2	-2.2	-1.3	-2.3	-1.5
Mother’s age at death	0.8	1.0	2.1	1.1	1.0	-0.4	-0.1	0.8	-0.7	-1.4	-1.4
Financial situation satisfaction	0.8	1.0	4.2	0.2	-0.6	-0.7	-0.8	-2.0	1.5	-0.0	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.7	0.4	-0.3	-0.1	-0.2	0.8	0.1	0.1	-0.1
Commuting to job workplace: Public transport	1.5	1.8	3.5	1.4	1.8	-0.6	-0.0	0.4	-1.5	-1.9	-1.6
Eye problems/disorders: Glaucoma	0.2	0.3	1.1	-0.5	-0.2	0.4	-0.0	-0.4	-0.1	0.7	1.1
Medication: Blood pressure	1.8	3.4	5.8	2.2	1.8	1.1	1.2	-2.0	-2.4	-1.1	-2.4
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.3	1.6	1.7	0.4	0.6	-1.1	-1.8	-1.3	-1.1
Supplements: Fish oil (including cod liver oil)	1.3	1.7	3.2	1.6	1.8	1.0	1.4	-1.5	-1.3	-0.4	-1.1
High cholesterol (Self-reported)	0.2	0.4	1.0	0.6	0.3	0.9	0.4	-1.0	0.6	-0.2	-0.3
Medication: Bendroflumethiazide	0.3	0.5	2.3	0.3	0.3	-0.6	-0.5	-0.7	-1.5	-0.4	-0.4
Medication: Paracetamol	0.7	1.1	2.5	-1.1	-0.9	-1.1	-1.4	0.7	1.6	0.6	0.8
Medication: Lisinopril	0.3	0.3	1.5	-0.0	-0.1	0.0	0.1	-0.1	-1.2	0.1	-1.0
Medication: Atorvastatin	0.2	0.3	1.5	-0.4	-0.0	0.2	-0.1	-0.1	1.2	0.2	0.6
Illnesses of father: High blood pressure	1.5	1.9	4.6	1.1	1.4	1.3	0.9	-0.7	-1.8	-1.1	-2.1
Alcohol drinker status: Never	0.5	0.6	2.7	0.8	0.5	-0.2	0.4	1.1	-1.6	-0.5	-0.0
Ever smoked	1.1	1.9	3.7	-1.6	-1.2	-0.4	-0.8	-1.7	1.9	1.4	1.3
Basal metabolic rate	0.5	2.8	9.4	-2.8	-3.1	1.0	0.6	0.2	0.6	1.8	0.0
Leg fat percentage (left)	0.9	3.3	5.2	-1.9	-2.3	-1.7	-2.1	-0.6	1.8	1.9	1.6
Arm fat-free mass (left)	0.5	2.7	9.9	-3.0	-3.1	0.1	-0.3	0.3	0.4	1.6	-0.3
Number of operations (self-reported)	0.7	1.1	3.5	-0.3	-0.8	0.2	-0.0	1.2	1.5	0.9	1.9
Average weekly beer plus cider intake	0.5	0.7	2.6	-0.6	-0.3	-0.2	-0.7	-0.7	1.6	0.6	1.1
Irritability	1.6	2.8	8.8	-1.4	-1.2	-1.6	-1.9	-0.8	3.0	0.9	1.5
Risk taking	0.5	0.8	2.0	1.0	0.8	-0.9	-0.7	0.4	-0.4	-1.4	-1.0
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.4	-0.5	-0.8	-0.8	-0.9	1.6	0.6	1.1	0.5
Fractured/broken bones in last 5 years	0.3	0.3	0.8	-0.8	-0.7	-0.6	-0.3	-0.6	0.0	0.9	0.1
Age started oral contraceptive pill	0.9	1.1	3.3	-0.9	-0.6	-1.8	-1.5	-0.9	-1.2	0.0	-0.0
Diastolic blood pressure, automated reading	0.5	1.6	4.9	-1.4	-2.1	0.8	0.3	0.2	0.7	2.2	0.5
Ever depressed for a whole week	0.8	0.9	5.2	-0.3	-0.5	-0.3	-0.4	-2.3	-0.8	0.2	-1.0
Unable to work because of sickness or disability	0.2	0.3	1.1	-0.9	-1.1	0.3	-0.3	-0.0	0.4	0.5	0.2
Commuting to job workplace: Cycle	0.5	0.6	1.2	0.4	0.9	-0.1	-0.4	-1.0	-0.7	-1.1	-1.1
Myopia	0.2	0.3	0.9	0.3	-0.0	0.8	0.8	1.0	0.5	0.1	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.8	0.3	1.0	-0.7	-0.2	1.4	0.2	-1.2	-0.3
Cholesterol lowering medication	2.7	4.0	7.1	2.7	2.1	1.7	1.5	-2.7	-1.2	-1.5	-2.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.1	-0.4	-1.2	-0.6	-0.7	-1.5	1.1	1.3	0.9
Pain experienced in last month	1.6	2.6	6.2	1.7	1.9	-0.9	-0.5	-0.7	-2.0	-1.7	-2.5
Supplements: Calcium	1.3	1.5	3.0	-0.7	-0.8	1.3	0.9	0.7	1.7	1.3	1.7
Basal cell carcinoma (self-reported)	0.6	0.7	1.8	-0.7	-1.3	0.2	-0.1	1.0	-0.6	1.3	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.6	-0.2	-1.1	1.1	0.8	0.5	1.1	1.3	0.4
Deep venous thrombosis (DVT) (self-reported)	2.3	2.9	4.6	-1.8	-1.9	-1.9	-2.1	0.3	1.4	1.4	2.1
Heart disease (siblings)	0.4	0.5	1.9	0.4	-0.1	0.4	0.2	0.3	1.4	-0.1	1.2
Alcohol drinker status: Previous	0.3	0.3	0.8	0.1	0.8	0.7	0.3	0.5	0.2	-0.9	0.1
Pack years of smoking	0.3	0.4	1.1	-0.5	-1.0	-0.3	-0.9	-0.2	0.3	0.7	0.3
Impedance of whole body	0.3	1.4	5.5	1.0	0.9	-0.1	0.1	-0.1	-1.5	-1.3	-2.4
Leg fat mass (left)	1.1	4.2	9.9	-2.8	-3.2	-1.5	-1.9	-0.1	1.8	2.2	1.5
Arm predicted mass (left)	0.5	2.6	9.7	-2.8	-3.1	0.3	-0.1	0.2	0.5	1.6	-0.0