[Hub]/) : Traits : Heel T-Score : ← →

chr14:34,480,400-36,471,214

Best TWAS P=1.38e-23 · Best GWAS P=1.49e-30 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP11-73E17.2	0.06	0.04	lasso	4	0.03	1.5e-03	9.5	9.4	5.9e-21	0.71	0.06	0.82	FALSE
2	GTEx	Adipose Visceral Omentum	SRP54	0.09	0.01	enet	17	0.02	3.8e-02	-8.4	-6.6	3.8e-11	-0.21	0.15	0.05	FALSE
3	GTEx	Artery Aorta	SRP54	0.10	0.14	lasso	1	0.11	8.8e-07	-10.0	-10.0	1.4e-23	-0.41	0.79	0.06	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	SRP54	0.19	0.06	enet	11	0.05	9.1e-03	-10.0	-9.5	2.3e-21	-0.49	0.09	0.32	TRUE
5	GTEx	Cells Transformed fibroblasts	SRP54	0.29	0.24	enet	18	0.21	1.9e-15	-10.0	-9.5	3.0e-21	-0.42	1.00	0.00	FALSE
6	GTEx	Cells Transformed fibroblasts	CFL2	0.14	0.08	enet	39	0.11	9.9e-09	-5.3	-8.1	4.0e-16	-0.37	0.55	0.10	FALSE
7	GTEx	Esophagus Mucosa	CFL2	0.13	0.06	enet	16	0.08	8.2e-06	-5.2	-6.7	1.8e-11	-0.42	0.42	0.14	FALSE
8	GTEx	Heart Atrial Appendage	SRP54	0.14	0.02	enet	11	0.02	4.9e-02	8.8	-7.2	7.2e-13	-0.24	0.18	0.06	TRUE
9	GTEx	Lung	RP11-85K15.2	0.12	0.08	lasso	6	0.06	4.4e-05	6.2	-7.0	2.2e-12	-0.25	0.94	0.00	TRUE
10	GTEx	Lung	RP11-73E17.2	0.09	0.01	lasso	8	0.01	9.9e-02	4.1	7.2	5.3e-13	0.43	0.25	0.34	FALSE
11	GTEx	Muscle Skeletal	PSMA6	0.13	0.14	lasso	2	0.12	4.6e-12	5.9	6.0	2.6e-09	0.22	1.00	0.00	FALSE
12	GTEx	Nerve Tibial	SRP54	0.16	0.02	enet	14	0.08	1.3e-06	-6.2	-6.6	5.2e-11	-0.31	0.74	0.05	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	FAM177A1	0.17	0.03	enet	20	0.04	2.0e-03	-5.8	-7.7	1.9e-14	-0.42	0.18	0.05	TRUE
14	GTEx	Skin Sun Exposed Lower leg	FAM177A1	0.19	0.04	lasso	10	0.10	1.7e-08	4.6	-5.9	3.6e-09	-0.31	0.83	0.03	FALSE
15	GTEx	Skin Sun Exposed Lower leg	RP11-85K15.2	0.10	0.07	lasso	3	0.09	1.1e-07	-9.1	-9.6	1.3e-21	-0.38	0.93	0.01	FALSE
16	GTEx	Testis	PPP2R3C	0.23	0.22	lasso	3	0.23	1.6e-10	-7.6	7.9	2.1e-15	0.28	0.99	0.00	TRUE
17	GTEx	Testis	BAZ1A	0.24	0.18	lasso	5	0.20	5.0e-09	-2.8	-7.2	6.5e-13	-0.69	0.06	0.93	FALSE
18	METSIM	Adipose	FAM177A1	0.05	0.01	bslmm	385	0.02	1.3e-03	-6.3	-6.4	1.4e-10	-0.36	0.61	0.02	FALSE
19	NTR	Blood	CFL2	0.05	0.04	lasso	3	0.04	1.3e-13	-5.3	-5.8	5.8e-09	-0.36	1.00	0.00	FALSE
20	NTR	Blood	FAM177A1	0.02	0.00	blup	381	0.01	6.0e-04	7.7	-8.9	4.2e-19	-0.55	0.03	0.82	FALSE
21	YFS	Blood	SRP54	0.12	0.14	lasso	10	0.15	1.4e-45	6.9	-6.9	6.6e-12	-0.37	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CFL2	0.03	0.03	blup	39	0.03	1.9e-03	-7.9	-7.5	6.4e-14	-0.36	0.02	0.04	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	CFL2	0.08	0.07	lasso	4	0.06	1.9e-04	-5.3	-5.8	5.9e-09	-0.33	0.41	0.06	TRUE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CFL2	0.06	0.07	lasso	4	0.07	1.9e-08	-5.2	-5.3	9.2e-08	-0.31	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	CFL2	0.05	0.05	blup	39	0.05	2.5e-06	-7.9	-7.1	1.2e-12	-0.32	0.37	0.03	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CFL2	0.04	0.02	lasso	4	0.03	3.8e-04	-5.2	-7.7	1.1e-14	-0.33	0.09	0.03	FALSE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CFL2	0.07	0.03	blup	39	0.05	4.7e-04	-4.8	-5.2	2.0e-07	-0.22	0.03	0.04	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMA6	0.05	0.00	blup	52	0.01	1.6e-02	2.4	5.2	2.3e-07	0.23	0.06	0.05	FALSE
29	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CFL2	0.17	0.17	blup	39	0.16	3.3e-06	-5.6	-5.2	2.0e-07	-0.24	0.42	0.03	FALSE
30	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PSMA6	0.17	0.00	blup	52	0.05	8.0e-03	3.1	6.6	5.2e-11	0.34	0.01	0.10	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	CFL2	0.08	0.03	blup	39	0.06	2.0e-06	-7.9	-7.8	9.5e-15	-0.45	0.34	0.28	FALSE