Best TWAS P=8.77e-13 · Best GWAS P=3.74e-18 conditioned to 4.64e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | CYTH1 | 0.03 | 0.01 | bslmm | 579 | 0.00 | 9.7e-03 | 5.3 | -5.9 | 2.8e-09 | -0.05 | 0.10 | 0.02 | TRUE |
| 2 | YFS | Blood | TIMP2 | 0.15 | 0.12 | bslmm | 631 | 0.12 | 6.3e-38 | 6.8 | -7.2 | 8.8e-13 | 0.02 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DNAH17 | 0.04 | 0.01 | blup | 99 | 0.02 | 1.2e-05 | 8.5 | 7.0 | 3.3e-12 | 0.52 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | USP36 | 0.38 | 0.24 | lasso | 2 | 0.18 | 6.2e-05 | 6.4 | -6.4 | 1.3e-10 | 0.03 | 0.05 | 0.27 | FALSE |