[Hub]/) : Traits : Heel T-Score : ← →

chr17:58,828,402-64,251,733

Best TWAS P=1.14e-25 · Best GWAS P=5.68e-98 conditioned to 6.21e-80

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial DDX5 0.12 0.13 lasso 2 0.12 1.5e-09 -10.3 10.3 8.0e-25 -0.05 0.00 1.00 FALSE
2 GTEx Artery Tibial TBX2 0.21 0.03 enet 37 0.06 1.4e-05 1.9 7.8 7.1e-15 0.39 0.74 0.06 TRUE
3 GTEx Brain Frontal Cortex BA9 TBX2 0.29 0.01 lasso 3 0.02 7.7e-02 6.4 7.1 1.1e-12 -0.02 0.04 0.05 TRUE
4 GTEx Brain Frontal Cortex BA9 RP11-332H18.4 0.40 0.05 lasso 16 0.07 6.4e-03 6.4 6.8 9.2e-12 -0.01 0.12 0.05 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia DDX42 0.23 0.04 lasso 12 0.07 8.1e-03 -4.9 6.1 8.1e-10 0.05 0.04 0.79 TRUE
6 GTEx Cells Transformed fibroblasts MRC2 0.10 0.02 enet 17 0.02 1.5e-02 -5.0 9.4 8.4e-21 0.01 0.01 0.94 TRUE
7 GTEx Lung MRC2 0.13 0.01 enet 12 0.06 1.6e-05 -7.0 6.5 6.7e-11 0.06 0.20 0.29 FALSE
8 GTEx Nerve Tibial RGS9 0.16 0.01 lasso 5 0.01 8.2e-02 -7.2 -7.2 5.4e-13 -0.07 0.06 0.37 TRUE
9 NTR Blood DDX5 0.10 0.04 lasso 3 0.04 5.2e-13 -10.3 10.5 1.1e-25 -0.05 0.00 1.00 TRUE
10 NTR Blood TANC2 0.01 0.00 bslmm 331 0.01 1.4e-04 2.1 -5.2 2.0e-07 -0.11 0.08 0.28 FALSE
11 YFS Blood AXIN2 0.20 0.05 enet 34 0.10 5.1e-31 4.5 -7.2 5.8e-13 -0.06 1.00 0.00 TRUE
12 YFS Blood DDX5 0.42 0.21 bslmm 215 0.21 7.7e-68 -10.3 10.3 5.8e-25 -0.04 0.00 1.00 FALSE
13 YFS Blood POLG2 0.02 0.01 lasso 5 0.02 7.3e-06 -10.3 -9.1 8.7e-20 0.05 0.00 1.00 FALSE
14 The Cancer Genome Atlas Esophageal Carcinoma METTL2A 0.14 0.03 blup 16 0.04 2.4e-02 3.3 5.4 6.2e-08 -0.01 0.00 0.40 FALSE