Best TWAS P=1.61e-33 · Best GWAS P=4.4e-35 conditioned to 0.000305
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | 10.3 | 12.1 | 1.6e-33 | 0.69 | 0.07 | 0.92 | TRUE |
| 2 | GTEx | Artery Aorta | ZNF827 | 0.13 | 0.14 | enet | 11 | 0.10 | 6.5e-06 | 7.6 | -9.3 | 1.8e-20 | -0.05 | 0.41 | 0.56 | TRUE |
| 3 | GTEx | Artery Tibial | ZNF827 | 0.16 | 0.08 | enet | 22 | 0.05 | 1.2e-04 | -7.0 | -7.9 | 3.4e-15 | -0.05 | 0.41 | 0.59 | FALSE |
| 4 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | -5.6 | -10.1 | 5.3e-24 | -0.50 | 0.06 | 0.17 | TRUE |
| 5 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | 6.6 | -6.0 | 1.6e-09 | -0.48 | 0.34 | 0.04 | FALSE |
| 6 | GTEx | Testis | LSM6 | 0.14 | 0.06 | enet | 17 | 0.04 | 6.4e-03 | -4.6 | -7.2 | 6.1e-13 | 0.07 | 0.13 | 0.16 | TRUE |
| 7 | GTEx | Vagina | HHIP-AS1 | 0.16 | 0.10 | lasso | 7 | 0.06 | 1.8e-02 | -9.4 | -10.9 | 1.1e-27 | -0.29 | 0.03 | 0.74 | FALSE |
| 8 | NTR | Blood | MMAA | 0.04 | 0.00 | bslmm | 343 | 0.01 | 1.1e-04 | 2.6 | -10.1 | 5.5e-24 | -0.09 | 0.11 | 0.19 | TRUE |
| 9 | YFS | Blood | ZNF827 | 0.02 | 0.00 | enet | 9 | 0.01 | 1.1e-03 | -7.6 | -6.3 | 3.3e-10 | -0.05 | 0.03 | 0.77 | FALSE |
| 10 | The Cancer Genome Atlas | Esophageal Carcinoma | OTUD4 | 0.15 | 0.06 | blup | 31 | 0.05 | 8.3e-03 | -8.0 | 11.0 | 5.2e-28 | 0.43 | 0.02 | 0.09 | FALSE |