Best TWAS P=2.59e-10 · Best GWAS P=6.04e-10 conditioned to 0.743
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | YFS | Blood | BRD7 | 0.18 | 0.17 | bslmm | 346 | 0.19 | 1.8e-58 | -5.8 | -6.3 | 2.6e-10 | 0.86 | 0.04 | 0.96 | TRUE |
| 1 | GTEx | Breast Mammary Tissue (Female) | BRD7 | 0.13 | -0.01 | enet | 10 | 0.00 | 4.4e-01 | 6.0 | -5.3 | 1.1e-07 | 0.11 | 0.04 | 0.20 | TRUE |
| 2 | GTEx | Whole Blood | BRD7 | 0.16 | 0.12 | enet | 9 | 0.12 | 4.2e-11 | -5.9 | -6.0 | 1.8e-09 | 0.95 | 0.02 | 0.98 | FALSE |
| 4 | NTR | Blood | ADCY7 | 0.07 | 0.06 | enet | 17 | 0.07 | 2.0e-20 | -5.9 | -5.7 | 1.0e-08 | 0.95 | 0.01 | 0.99 | FALSE |
| 3 | METSIM | Adipose | BRD7 | 0.06 | 0.05 | lasso | 6 | 0.05 | 1.1e-07 | -5.9 | -5.7 | 1.2e-08 | 0.87 | 0.02 | 0.98 | FALSE |
| 6 | YFS | Blood | PAPD5 | 0.03 | 0.01 | enet | 13 | 0.02 | 1.4e-07 | -5.8 | -5.6 | 2.5e-08 | 0.74 | 0.02 | 0.98 | FALSE |