[Hub]/) : Traits : Hypothyroidism (self reported) : ← →

chr17:39,589,083-41,265,776

Best TWAS P=1.84e-12 · Best GWAS P=1.86e-12 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Muscle Skeletal	RAB5C	0.10	0.07	lasso	2	0.06	3.9e-06	7.0	7.0	1.8e-12	1.00	0.00	1.00	TRUE
9	The Cancer Genome Atlas	Thyroid Carcinoma	HSPB9	0.05	0.05	lasso	2	0.04	4.7e-05	7.0	7.0	2.0e-12	1.00	0.00	1.00	FALSE
6	GTEx	Pancreas	RAB5C	0.14	0.13	lasso	2	0.08	2.6e-04	7.0	7.0	3.3e-12	1.00	0.00	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RAB5C	0.21	0.18	bslmm	326	0.18	8.1e-21	7.0	6.8	9.7e-12	0.96	0.00	1.00	FALSE
5	GTEx	Nerve Tibial	RAB5C	0.14	0.08	lasso	8	0.07	1.1e-05	7.0	6.1	1.2e-09	0.95	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	RAB5C	0.19	0.02	lasso	6	0.02	3.7e-02	4.6	5.8	8.6e-09	0.94	0.01	0.92	FALSE
8	METSIM	Adipose	PTRF	0.03	0.02	lasso	3	0.01	3.3e-03	4.5	-5.3	9.9e-08	-0.60	0.31	0.62	FALSE
3	GTEx	Esophagus Muscularis	RAB5C	0.20	0.12	lasso	6	0.11	3.1e-07	4.6	5.3	1.1e-07	0.91	0.01	0.99	FALSE
7	GTEx	Stomach	RAB5C	0.15	0.10	lasso	3	0.10	2.5e-05	4.6	5.3	1.4e-07	0.90	0.02	0.98	FALSE