TWAS hub - HSPB9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Liver Hepatocellular Carcinoma	0.044	0.032	0.0085	0.053	0.042	0.038	NA	0.047	1.6e-03	0.00460	0.00680	NA	2.8e-03
2	TCGA	Testicular Germ Cell Tumors	0.276	0.131	0.0013	0.083	0.032	0.040	NA	0.077	7.1e-04	0.02600	0.01500	NA	1.1e-03
3	TCGA	Thyroid Carcinoma	0.052	0.030	0.0001	0.052	0.030	0.031	NA	0.043	8.1e-06	0.00055	0.00049	NA	4.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Medication: Levothyroxine sodium	13.3	22.4	45.5	4.6	1.1	6.7
Hypothyroidism/myxoedema (self-reported)	12.3	24.1	48.4	4.6	1.6	7.0
Hypothyroidism (self reported)	10.4	23.9	49.4	4.6	1.1	7.0
Medication: Co-codamol	7.2	8.3	13.4	3.4	-0.1	3.7
Breastfed as a baby	6.9	8.6	14.0	-3.7	0.6	-3.4
Depression (Nagel 2018)	6.1	9.1	14.3	3.6	-0.2	3.8
Taking other prescription medications	6.1	9.4	17.2	3.3	-0.1	4.2
Frequency of depressed mood in last 2 weeks	6.0	8.4	15.0	3.2	-0.2	3.9
Illnesses of father: Heart disease	5.9	8.2	14.1	3.0	1.4	3.8
Heart disease (mother)	4.9	6.0	10.9	3.3	-0.9	2.5
Heart disease (siblings)	4.7	5.8	6.6	2.6	-2.4	2.2
Medication: Atorvastatin	4.6	5.7	8.6	2.4	-1.6	2.9
Blood White Count	4.2	30.8	46.2	6.8	0.2	6.8
Number of self-reported non-cancer illnesses	4.2	7.3	13.8	2.9	-0.0	3.7
Long-standing illness, disability or infirmity	4.1	6.2	10.7	2.7	0.7	3.3
Frequency of unenthusiasm / disinterest in last 2 weeks	3.8	5.1	8.0	2.5	-0.8	2.8
Medication: Gliclazide	3.6	4.1	6.2	2.5	0.2	2.5
Coronary Artery Disease (CAD)	3.4	4.1	7.5	2.7	0.0	2.2
Other serious medical condition/disability diagnosed by doctor	3.3	4.2	6.7	2.1	1.3	2.6
Migraine (self-reported)	3.0	3.7	5.1	2.2	-1.1	2.3
Supplements: Vitamin C	3.0	3.5	4.5	2.1	-1.8	1.7
Prostate Cancer	2.9	4.0	7.7	2.8	0.1	2.1
Asthma	2.9	5.7	9.2	2.8	0.0	3.0
Length of working week for main job	2.8	3.1	5.3	-0.8	-2.3	-1.8
Medication for pain relief, constipation, heartburn	2.8	4.8	5.9	-2.2	1.9	-2.4
Ever taken oral contraceptive pill	2.8	3.1	5.3	-1.6	-1.2	-2.3
Alzheimer’s Disease (in mother)	2.6	3.1	4.9	2.1	0.1	2.2
Pain all over the body in last month	2.6	2.8	4.7	2.2	-0.3	1.9
Ulcerative Colitis	2.5	3.6	6.5	-2.5	0.0	-2.1
Lung FVC	2.5	12.5	22.2	-3.6	-1.4	-4.7
Father’s age at death	2.5	3.3	4.5	-2.1	1.7	-1.6
Asthma (self-reported)	2.5	5.0	8.2	2.6	-0.2	2.9
Serious illness, injury or assault to yourself	2.4	2.9	3.6	1.8	-1.4	1.9
Medication: Aspirin	2.4	3.1	6.6	1.5	0.7	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	4.3	2.1	0.2	2.0
Irritable Bowel Disease (IBD)	2.3	5.5	12.4	-3.5	0.4	-2.0
Body Mass Index (BMI) (2010)	2.3	3.1	5.7	-2.4	0.0	-1.9
Lupus	2.3	3.4	5.9	2.4	0.6	2.0
Allergy or Eczema	2.3	6.0	12.9	1.9	1.1	3.6
Tinnitus: Yes, now most or all of the time	2.3	2.6	4.1	-2.0	1.3	-1.5
Ever had hysterectomy (womb removed)	2.2	2.4	4.3	-2.1	-0.3	-1.7
Diabetes (mother)	2.2	2.8	4.6	1.9	0.1	2.1
Rheumatoid Arthritis	2.1	2.8	4.9	1.7	-0.8	2.2
Average weekly spirits intake	2.1	2.7	7.6	0.5	2.8	0.3
Time employed in main current job	2.1	2.4	4.2	-1.3	-1.1	-2.1
Medication: Aspirin	2.1	2.7	5.6	1.3	0.9	2.4
Illnesses of father: None of the above (group 1)	2.1	2.5	3.1	-1.2	-1.7	-1.8
Ulcerative Colitis (UC)	2.0	3.7	8.2	-2.9	0.2	-1.7
Respiratory disease	2.0	4.5	6.8	2.6	-0.9	2.4
Diabetes diagnosed by doctor	2.0	3.3	4.5	1.5	1.7	2.1
Back pain experienced in last month	2.0	2.8	3.7	-1.9	1.3	-1.8
Osteoarthritis (self-reported)	2.0	2.6	3.9	2.0	1.2	1.5
Age at First Birth	1.9	2.7	6.3	-2.5	0.0	-1.3
Neuroticism (2016)	1.9	2.8	4.0	1.9	1.0	2.0
Type 2 Diabetes (T2D) (2018)	1.9	3.6	7.2	1.8	0.7	2.7
High blood pressure (mother)	1.9	2.7	4.1	-2.0	1.1	-1.6
Wheeze or whistling in the chest in last year	1.9	3.4	5.9	1.9	-0.8	2.4
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.1	10.1	-3.2	0.9	-1.2
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	4.0	1.5	0.3	2.0
Leg fat percentage (right)	1.8	6.4	11.7	-2.7	0.6	-3.4
Eye problems/disorders: None of the above	1.8	2.1	3.6	-1.7	0.3	-1.9
Eye problems/disorders: Cataract	1.8	2.1	3.9	1.5	-0.3	2.0
Eye problems/disorders: Glaucoma	1.8	2.2	5.0	-0.8	2.2	-0.9
Crohns Disease (2012)	1.7	2.7	5.7	-2.4	0.0	-1.6
Vitamin and mineral supplements	1.7	2.3	3.5	-1.5	1.9	-1.1
Age when periods started (menarche)	1.7	4.0	7.0	2.7	-1.2	1.8
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	4.9	-1.7	2.2	-0.6
Diabetes (father)	1.6	2.0	4.3	2.1	-0.1	1.2
Stomach or abdominal pain in last month	1.6	2.0	4.4	2.1	0.1	1.3
Alcohol intake versus 10 years previously	1.6	2.4	4.7	-1.6	0.5	-2.2
Number of children fathered	1.6	1.8	2.4	1.2	1.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	5.1	2.3	0.3	2.2
Alzheimer’s Disease (in father)	1.5	1.6	3.1	-1.2	0.6	-1.8
Hayfever, allergic rhinitis or eczema	1.5	3.3	7.3	1.5	0.7	2.7
Medication: Atenolol	1.5	1.8	2.4	1.6	-1.1	1.3
Heart attack	1.5	2.0	4.0	1.2	0.6	2.0
Allergy	1.5	3.5	7.3	-1.7	-0.6	-2.7
Falls in the last year	1.5	2.1	2.5	1.3	-1.4	1.6
Had major operations	1.5	1.8	2.8	1.5	0.5	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	2.3	1.5	-1.4	1.1
Qualifications: CSEs or equivalent	1.4	1.8	3.4	1.8	-0.7	1.3
Medication: Lansoprazole	1.4	1.6	4.1	2.0	-0.2	0.8
Medication: Paracetamol	1.4	2.2	5.5	1.0	-2.3	-0.2
Leg fat percentage (left)	1.4	5.1	10.5	-2.2	0.2	-3.2
Heart attack/myocardial infarction (self-reported)	1.4	1.8	3.6	1.2	0.6	1.9
Verbal and Numeric Reasoning (VNR)	1.3	3.1	5.0	-2.2	0.3	-2.0
Headache pain in last month	1.3	2.2	4.7	2.2	-0.3	1.3
Shortness of breath walking on level ground	1.3	1.5	2.4	1.4	0.3	1.5
Ever had bowel cancer screening	1.3	1.6	4.7	-0.1	2.2	0.1
HDL Cholesterol	1.2	2.0	4.4	-1.3	0.0	-2.1
Type 2 Diabetes (T2D) (2012)	1.2	1.3	3.9	0.3	0.0	2.0
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.8	-0.8	-0.0	-2.0
Systolic blood pressure, automated reading	1.2	3.6	6.2	-2.5	-0.5	-2.1
Diabetes (self-reported)	1.2	1.9	2.3	1.1	1.5	1.4
Medication: Ventolin 100micrograms inhaler	1.2	1.5	3.1	1.0	-0.6	1.8
Medication: Allopurinol	1.2	1.5	3.6	1.9	0.4	0.9
Suffer from ‘nerves’	1.2	1.8	3.2	1.5	-0.2	1.8
Overall health rating	1.2	2.6	4.2	2.0	0.3	1.9
Leg pain on walking	1.2	1.4	2.1	1.4	-0.4	1.4
Risk taking	1.2	1.7	3.6	-1.2	-0.2	-1.9
Neuroticism (Nagel 2018)	1.1	2.6	4.0	2.0	-0.0	2.0
Worry (Nagel 2018)	1.1	2.4	4.6	1.5	0.5	2.1
Heel T-Score	1.1	8.6	18.2	-4.3	1.1	-2.5
Depression (self-reported)	1.1	1.4	2.4	1.6	-1.1	0.6
Medication: Paracetamol	1.1	1.8	3.6	1.3	-1.9	0.1
Health satisfaction	1.1	1.5	2.5	1.6	-0.1	1.4
Chest pain or discomfort	1.1	1.6	4.2	0.9	-0.1	2.0
Miserableness	1.1	2.0	3.6	1.9	0.5	1.5
Medication: Blood pressure	1.1	2.2	5.0	-2.2	1.1	-0.6
High cholesterol (Self-reported)	1.1	2.0	2.8	1.3	-1.7	1.2
Fractured/broken bones in last 5 years	1.1	1.4	2.0	1.2	-1.4	0.8
Intelligence (Savage-Jansen 2018)	1.0	3.1	4.9	-2.2	0.8	-1.9
Crohns Disease (2017)	1.0	2.2	5.3	-2.3	0.2	-1.1
Height	1.0	19.2	29.5	5.3	-0.4	5.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	3.3	1.2	0.0	1.8
Noisy workplace	1.0	1.2	2.6	-0.7	-1.6	0.6
Mouth/teeth dental problems: Dentures	1.0	1.6	2.6	1.6	-0.6	1.4
Standing height	1.0	9.8	18.1	3.3	-0.9	4.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.2	2.4	1.6	0.9	0.6
Diastolic blood pressure, automated reading	1.0	3.0	5.9	-1.0	-1.4	-2.4
Blood Eosinophil Count	0.9	7.1	11.8	3.1	-0.4	3.4
Number of treatments/medications taken	0.9	1.6	2.9	1.3	-0.2	1.7
Sensitivity / hurt feelings	0.9	1.5	3.8	2.0	-0.0	0.9
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.2	0.8	0.1	1.5
Medication: Metformin	0.9	1.3	2.3	0.6	1.5	1.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	1.6	-1.1	0.1	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	5.7	-2.4	-0.3	-0.6
Worrier / anxious feelings	0.9	1.7	4.0	1.0	0.4	2.0
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	1.8	1.3	-0.7	1.1
Medication: Amlodipine	0.9	1.3	3.0	-0.9	-0.2	-1.7
Exposure to tobacco smoke outside home	0.9	1.2	3.1	0.6	-1.8	0.3
Illnesses of siblings: Diabetes	0.9	1.1	2.9	0.6	-1.7	-0.3
Average weekly champagne plus white wine intake	0.9	1.2	1.4	-1.2	-1.0	-1.2
Average weekly fortified wine intake	0.8	1.0	1.5	-0.5	1.2	-1.1
Sitting height	0.8	5.6	10.2	2.5	-0.5	3.2
Impedance of arm (right)	0.8	3.9	5.8	2.4	-1.3	2.0
Medication: Cholesterol lowering	0.8	1.2	1.7	1.3	-0.8	1.2
Hair/balding pattern: Pattern 4	0.8	1.9	3.9	-2.0	0.2	-1.4
Peak expiratory flow (PEF)	0.8	1.7	2.5	1.6	-1.0	1.3
Gout (self-reported)	0.8	1.1	2.2	1.5	0.3	1.1
Breast cancer (self-reported)	0.8	1.0	1.4	-0.7	-1.0	-1.2
Commuting to job workplace: Public transport	0.8	0.9	1.8	-1.4	1.0	0.1
Alcohol drinker status: Never	0.8	0.9	1.3	-1.1	1.2	-0.4
Age started oral contraceptive pill	0.8	1.0	2.2	-1.5	0.5	-0.7
Cholesterol lowering medication	0.8	1.2	2.0	0.6	-1.1	1.4
Hearing difficulty/problems: Yes	0.7	1.1	2.3	-1.5	0.9	-0.2
Alcohol usually taken with meals	0.7	1.1	2.0	0.8	0.9	1.4
Had other major operations	0.7	0.8	1.8	-0.8	-0.1	-1.3
Neuroticism score	0.7	1.6	2.8	1.7	0.5	1.3
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	2.2	-1.2	-0.1	-1.5
Glaucoma (self-reported)	0.7	0.8	2.2	-0.4	1.5	-0.1
Age at last live birth	0.7	1.0	1.7	0.4	1.3	1.1
Family relationship satisfaction	0.7	0.9	1.8	0.9	-1.3	-0.2
Smoking status: Current	0.7	1.2	3.1	-0.4	1.8	-0.5
Wears glasses or contact lenses	0.7	0.8	1.8	-1.4	0.3	-0.7
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.5	1.2	0.0	1.0
Medication: Bendroflumethiazide	0.7	1.1	1.3	-1.1	0.9	-1.1
Pack years of smoking	0.7	1.0	2.2	-0.9	-1.5	-0.1
Mean Putamen Volume	0.6	0.7	1.1	-0.3	-1.1	-1.0
Cardiovascular Disease	0.6	1.9	2.7	1.6	0.8	1.5
Relative age of first facial hair	0.6	1.2	2.3	1.2	0.3	1.5
Pack years adult smoking proportion	0.6	0.9	1.7	-1.0	-1.3	-0.2
Maternal smoking around birth	0.6	0.8	1.7	-0.5	1.3	-0.7
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.3	-0.6	-0.7	-1.1
Medication: Ramipril	0.6	0.8	1.8	0.8	-0.3	1.3
Prospective memory result	0.6	0.7	2.2	0.1	-1.5	0.2
Impedance of arm (left)	0.6	2.9	4.5	2.1	-1.2	1.6
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.4	1.2	0.5	0.6
Birth weight	0.6	1.4	1.9	-1.2	0.9	-1.4
Comparative body size at age 10	0.6	1.5	2.5	-0.9	1.2	-1.6
Age at first live birth	0.6	1.1	2.8	0.6	0.2	1.7
Number of full sisters	0.6	0.8	1.2	-0.9	0.6	-1.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.2	-0.8	0.5	-1.1
Medication: Lisinopril	0.6	0.8	1.1	-1.1	1.1	-0.5
Depressed Affect (Nagel 2018)	0.5	1.1	2.2	1.5	0.1	1.0
Major Depression (MDD)	0.5	0.6	1.4	0.5	1.2	0.5
Reaction Time	0.5	1.0	3.0	0.4	-1.7	0.1
Hand grip strength (left)	0.5	1.3	2.1	-1.2	1.4	-0.5
Angina	0.5	0.7	0.8	0.8	-0.9	0.7
Townsend deprivation index at recruitment	0.5	0.7	1.1	-1.1	-0.3	-1.0
Chronic bronchitis/emphysema (father)	0.5	0.5	0.9	0.9	-0.5	0.7
Number of incorrect matches in round	0.5	0.9	1.9	-0.3	-1.4	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.1	0.6	-0.1	1.5
Hair/balding pattern: Pattern 2	0.5	0.6	1.5	0.5	-1.2	-0.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.5	0.5	-1.2	-0.1
Loud music exposure frequency	0.5	0.6	1.5	-0.3	-1.2	-0.4
High blood pressure (siblings)	0.5	0.7	1.1	-1.0	0.2	-1.1
Neck or shoulder pain in last month	0.5	0.7	1.6	0.7	1.3	0.0
Medication: Ibuprofen	0.5	0.6	1.1	1.0	-0.7	0.4
Mean time to correctly identify matches	0.5	0.9	1.6	0.8	-1.3	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	0.6	0.7	0.7	0.7
Qualifications: nursing, teaching	0.5	0.8	1.3	0.3	1.0	1.2
Average weekly beer plus cider intake	0.5	0.7	1.6	-1.3	0.1	-0.8
Irritability	0.5	0.8	1.0	0.8	1.0	0.8
Supplements: Calcium	0.5	0.6	1.2	0.5	0.4	1.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.3	0.4	0.0	1.2
Ovarian Cancer	0.4	0.5	1.5	-0.2	-1.2	0.2
Schizophrenia (2014)	0.4	1.0	1.8	-1.3	0.8	-0.7
Triglycerides	0.4	0.7	1.3	-1.1	0.0	-0.8
Waist Hip Ratio (WHR)	0.4	1.7	4.1	0.9	0.4	2.0
Systolic Blood Pressure	0.4	2.2	5.2	-2.3	0.4	-1.1
Smoking Status	0.4	0.9	2.3	-0.2	1.5	0.5
Neuroticism	0.4	0.9	1.3	1.1	0.0	1.1
Medication for hormone replacement therapy	0.4	0.5	1.1	-0.1	-0.5	-1.1
Current tobacco smoking	0.4	0.6	1.8	-0.1	1.4	-0.2
Body mass index (BMI)	0.4	1.8	3.5	-1.2	0.7	-1.9
Hearing difficulty/problems with background noise	0.4	0.7	1.7	-1.3	0.4	-0.4
Had menopause	0.4	0.5	1.1	-1.0	0.0	-0.6
Medication: Simvastatin	0.4	0.5	1.1	0.6	-0.3	1.0
Illnesses of siblings	0.4	0.6	1.7	0.1	1.3	0.4
Hair/balding pattern: Pattern 3	0.4	0.6	1.1	-1.1	0.4	-0.7
Happiness	0.4	0.5	1.3	0.4	-1.1	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	1.0	-0.7	-0.0
Lung cancer (father)	0.4	0.4	0.7	-0.8	-0.4	-0.7
Illnesses of mother	0.4	0.5	1.3	-0.5	-0.1	-1.1
Pulse wave reflection index	0.4	0.5	1.1	-1.1	-0.3	0.6
Medication: Omeprazole	0.4	0.5	0.8	-0.6	-0.6	-0.9
Leg fat mass (right)	0.4	1.6	3.2	-1.2	0.2	-1.8
Alcohol intake frequency.	0.4	0.9	2.2	-0.3	1.5	-0.6
Knee pain experienced in last month	0.4	0.5	0.9	0.8	-0.9	0.3
Hypertension (Self-reported)	0.4	1.1	2.8	-0.7	1.7	0.1
Smoking status: Previous	0.4	0.6	1.1	0.4	-1.1	0.7
Leg fat-free mass (right)	0.4	2.0	3.2	1.8	0.1	1.7
Mood swings	0.4	0.8	1.1	1.0	-1.1	0.5
Leg predicted mass (right)	0.4	2.2	3.6	1.9	0.1	1.8
Supplements: Fish oil (including cod liver oil)	0.4	0.5	0.7	0.9	0.4	0.8
Number of operations (self-reported)	0.4	0.6	1.3	1.1	0.7	0.3
Unable to work because of sickness or disability	0.4	0.5	1.3	0.2	-1.2	0.2
Commuting to job workplace: Cycle	0.4	0.5	1.3	0.1	-1.2	0.2
Myopia	0.4	0.5	0.8	-0.8	0.9	0.3
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.6	-0.3	-1.3	-1.2
Pain experienced in last month	0.4	0.7	1.2	-1.1	0.8	-0.7
Impedance of whole body	0.4	2.0	3.8	1.3	-2.0	0.7
Bipolar Disorder (2018)	0.3	0.5	1.3	-0.6	0.0	-1.1
Alzheimer’s Disease (including proxy)	0.3	0.5	0.8	0.9	0.6	0.5
Primary Biliary Cirrhosis	0.3	0.5	0.9	0.4	-0.5	1.0
BMI	0.3	1.9	3.8	-0.8	1.9	-1.1
Tanning	0.3	3.7	4.6	-2.2	1.6	-2.0
Impedance of leg (right)	0.3	1.5	2.2	-1.0	-1.5	-1.1
Leg fat-free mass (left)	0.3	1.4	2.2	1.4	0.1	1.5
Hand grip strength (right)	0.3	0.9	1.2	-1.1	1.0	-0.6
Relative age voice broke	0.3	0.5	0.8	0.8	-0.3	0.9
High blood pressure	0.3	0.7	1.8	-0.4	1.3	0.5
Impedance of leg (left)	0.3	1.4	3.4	-0.3	-1.9	-0.8
Leg predicted mass (left)	0.3	1.3	2.1	1.4	0.1	1.5
Financial difficulties in last 2 years	0.3	0.4	0.6	0.4	0.8	-0.7
Mouth/teeth dental problems	0.3	0.4	0.7	-0.6	-0.2	-0.8
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.6	0.7	0.7	0.5
Fluid intelligence score	0.3	0.7	0.9	-0.9	-0.6	-1.0
Tense / ‘highly strung’	0.3	0.5	1.4	0.2	-0.1	1.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.0	-1.0	-0.2	-0.7
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.7	-0.5	-0.8	-0.3
Body fat percentage	0.3	1.1	3.0	-0.6	-0.2	-1.7
Number of full brothers	0.3	0.4	0.5	0.7	-0.6	-0.6
Worry too long after embarrassment	0.3	0.5	0.9	0.2	-1.0	0.7
Pulse wave peak to peak time	0.3	0.4	1.1	1.0	-0.3	-0.1
Qualifications: College or University degree	0.3	1.0	1.6	-1.3	-1.1	0.0
Angina (self-reported)	0.3	0.4	0.9	0.5	-0.9	0.3
Comparative height size at age 10	0.3	1.7	2.8	1.6	-0.0	1.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.1	-0.1	1.1	-0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.5	-0.6	-0.7	-0.7
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.6	-0.5	-0.6	-0.8
Loneliness, isolation	0.3	0.5	0.8	0.9	-0.6	-0.5
Mineral and other dietary supplements	0.3	0.5	0.9	-1.0	-0.5	-0.4
Osteoporosis (self-reported)	0.3	0.4	1.0	0.5	-1.0	-0.2
Illnesses of father: High blood pressure	0.3	0.3	0.8	-0.9	0.4	-0.2
Ever depressed for a whole week	0.3	0.3	0.6	-0.6	0.8	-0.2
Alcohol drinker status: Previous	0.3	0.3	0.5	-0.7	-0.2	-0.7
Leg fat mass (left)	0.3	1.2	2.8	-0.9	0.1	-1.7
Bipolar Disorder or Schizophrenia	0.2	0.6	0.8	-0.9	0.2	-0.9
Blood Platelet Count	0.2	2.6	4.5	-2.1	1.1	-1.5
Blood Red Count	0.2	2.4	5.3	-1.3	-0.3	-2.3
Fed-up feelings	0.2	0.3	0.6	0.7	0.5	0.2
Supplements: Glucosamine	0.2	0.3	0.8	-0.2	0.0	-0.9
Forced vital capacity (FVC)	0.2	0.9	2.7	0.2	-1.6	0.0
Qualifications: None of the above	0.2	0.4	0.9	0.0	-0.5	-0.9
Number of live births	0.2	0.2	0.4	-0.5	0.2	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.9	0.2	-1.4	-0.0
Pulse rate	0.2	0.4	0.8	0.9	-0.1	-0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	-0.7	0.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.5	-0.6	0.7	0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.4	-0.7	-0.1	-0.4
Medication: Seretide 50 evohaler	0.2	0.3	0.6	0.2	0.8	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	0.3	0.6	0.2
Arm fat percentage (left)	0.2	0.8	2.1	-0.4	0.2	-1.4
Average weekly red wine intake	0.2	0.3	0.5	0.3	0.7	0.6
Mother’s age at death	0.2	0.2	0.3	0.5	-0.6	0.0
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.5	-0.7	-0.2	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.4	-0.6	-0.4	-0.4
Schizophrenia (2018)	0.1	0.2	0.5	-0.7	0.3	-0.2
Breast Cancer	0.1	0.2	0.4	0.6	0.4	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.1	-0.2	0.0	0.4
HbA1C	0.1	0.1	0.2	-0.5	0.0	0.2
Lung FEV1/FVC ratio	0.1	0.3	0.4	0.4	0.6	0.6
Chronotype (morning person)	0.1	0.3	0.8	0.9	0.1	0.0
Severe depression (siblings)	0.1	0.1	0.2	0.2	-0.3	0.4
Trunk fat percentage	0.1	0.4	0.8	0.2	-0.6	-0.9
Multivitamins +/- minerals	0.1	0.1	0.4	0.1	0.6	-0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.1	0.2	0.5
Trunk fat mass	0.1	0.2	0.3	0.5	-0.3	-0.6
Waist circumference	0.1	0.3	0.6	-0.4	0.8	-0.2
Nervous feelings	0.1	0.2	0.5	0.3	0.7	0.2
Arm fat percentage (right)	0.1	0.6	1.6	-0.4	0.1	-1.3
Trunk fat-free mass	0.1	0.6	1.1	0.6	0.7	1.1
Hip circumference	0.1	0.4	0.8	0.9	0.5	0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	-0.6	0.2	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.8	0.2	-0.9	-0.3
Arm fat mass (right)	0.1	0.4	0.9	-0.2	0.5	-0.9
Trunk predicted mass	0.1	0.6	1.0	0.5	0.8	1.0
Exposure to tobacco smoke at home	0.1	0.2	0.3	-0.2	-0.3	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.4	-0.1	-0.3	-0.6
Birth weight of first child	0.1	0.1	0.2	-0.2	-0.3	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.4	1.0	-0.1	-1.0	-0.5
Medication: Blood pressure	0.1	0.2	0.3	0.6	0.1	0.5
Whole body fat mass	0.1	0.3	1.0	-0.1	-0.1	-1.0
Pulse rate, automated reading	0.1	0.2	0.7	0.8	0.2	-0.2
Whole body fat-free mass	0.1	0.7	1.2	0.8	0.4	1.1
Friendships satisfaction	0.1	0.1	0.2	0.3	0.5	0.3
Medication for cholesterol	0.1	0.1	0.2	0.4	0.4	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.7	-0.3	0.4	-0.8
Whole body water mass	0.1	0.8	1.5	0.9	0.5	1.2
Arm fat mass (left)	0.1	0.6	1.3	-0.4	0.5	-1.1
Ever smoked	0.1	0.1	0.2	-0.4	-0.4	-0.0
Basal metabolic rate	0.1	0.5	0.9	0.8	0.4	0.9
Basal cell carcinoma (self-reported)	0.1	0.1	0.3	0.1	-0.2	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	0.3	-0.2	0.3
Fasting Glucose	0.0	0.0	0.1	-0.3	0.0	0.2
LDL Cholesterol	0.0	0.1	0.2	-0.4	0.0	0.2
Hair Pigment	0.0	0.9	2.4	1.5	-0.4	0.2
Supplements: Zinc	0.0	0.0	0.0	0.2	-0.1	-0.1
Past tobacco smoking	0.0	0.0	0.0	0.0	-0.1	-0.1
Weight	0.0	0.0	0.1	0.3	0.2	0.0
Blood clot in the leg (DVT)	0.0	0.0	0.1	0.2	-0.3	-0.0
Arm fat-free mass (right)	0.0	0.1	0.1	0.1	0.3	0.2
Emphysema/chronic bronchitis	0.0	0.1	0.1	0.2	-0.3	0.1
Arm predicted mass (right)	0.0	0.1	0.1	0.1	0.4	0.2
Commuting to job workplace: Walk	0.0	0.1	0.1	-0.2	-0.3	0.1
Guilty feelings	0.0	0.0	0.1	0.3	0.0	-0.0
Hearing aid user	0.0	0.0	0.0	-0.1	0.1	0.2
Financial situation satisfaction	0.0	0.0	0.1	0.2	0.1	-0.2
Arm fat-free mass (left)	0.0	0.1	0.1	-0.1	0.3	0.4
Arm predicted mass (left)	0.0	0.1	0.2	0.1	0.3	0.5

Hub : Genes

HSPB9

Models

Trait associations