[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) :

chr22:37,394,391-39,042,221

Best TWAS P=2.64e-08 · Best GWAS P=4.16e-08 conditioned to 0.00373

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TRIOBP 0.13 0.14 lasso 7 0.14 3.9e-11 -5.2 5.2 1.7e-07 0.61 0.04 0.96 FALSE
2 GTEx Artery Aorta GCAT 0.16 0.15 lasso 2 0.14 5.4e-08 -5.2 -5.2 1.8e-07 -0.55 0.03 0.97 FALSE
3 GTEx Artery Aorta C22orf23 0.10 0.01 enet 24 0.02 1.6e-02 -4.2 -5.1 2.7e-07 -0.45 0.12 0.55 FALSE
4 GTEx Esophagus Gastroesophageal Junction TRIOBP 0.20 -0.01 lasso 7 0.00 2.0e-01 -4.7 5.3 1.1e-07 0.58 0.06 0.65 FALSE
5 GTEx Muscle Skeletal GCAT 0.13 0.10 enet 17 0.10 3.9e-10 -5.2 -5.3 1.4e-07 -0.60 0.03 0.97 FALSE
6 GTEx Stomach TRIOBP 0.10 0.03 lasso 5 0.03 1.9e-02 -4.7 5.1 3.1e-07 0.57 0.07 0.66 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ANKRD54 0.05 0.01 blup 31 0.02 1.3e-03 -5.1 5.6 2.6e-08 0.55 0.01 0.89 TRUE
8 The Cancer Genome Atlas Prostate Adenocarcinoma TRIOBP 0.07 0.04 blup 67 0.03 2.1e-04 -4.3 5.2 2.5e-07 0.67 0.23 0.72 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma GCAT 0.02 0.03 blup 29 0.03 1.4e-03 -5.2 -5.2 2.3e-07 -0.58 0.02 0.74 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma TRIOBP 0.22 0.25 enet 37 0.27 6.9e-26 -4.8 5.3 1.0e-07 0.72 0.13 0.87 FALSE