[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) :

chr22:39,064,209-40,571,499

Best TWAS P=1.91e-13 · Best GWAS P=2.46e-13 conditioned to 0.000455

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MGAT3 0.04 0.00 blup 392 0.00 1.9e-01 -6.8 6.4 1.4e-10 -0.73 0.04 0.69 FALSE
2 GTEx Adipose Subcutaneous MGAT3 0.08 0.04 lasso 4 0.04 4.3e-04 -6.8 7.0 2.0e-12 -0.96 0.03 0.96 FALSE
3 GTEx Breast Mammary Tissue MGAT3 0.15 0.01 lasso 4 0.00 2.3e-01 -6.5 6.4 1.1e-10 -0.87 0.03 0.64 FALSE
4 GTEx Esophagus Muscularis MGAT3 0.09 0.02 enet 15 0.02 1.3e-02 -6.0 7.3 2.1e-13 -0.46 0.11 0.50 FALSE
5 GTEx Heart Atrial Appendage MGAT3 0.14 0.14 lasso 2 0.12 3.5e-06 -7.2 7.2 6.4e-13 -0.97 0.01 0.99 FALSE
6 GTEx Nerve Tibial SYNGR1 0.26 0.18 enet 27 0.21 3.6e-15 -6.5 -6.2 4.2e-10 0.88 0.03 0.97 FALSE
7 GTEx Nerve Tibial TAB1 0.15 0.13 lasso 5 0.15 1.0e-10 -6.4 -6.3 3.7e-10 0.85 0.53 0.47 FALSE
8 GTEx Skin Sun Exposed Lower leg MGAT3 0.13 0.05 lasso 3 0.02 4.7e-03 -7.2 7.0 2.2e-12 -0.96 0.01 0.98 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma MGAT3 0.04 0.01 blup 48 0.04 2.3e-05 -4.6 7.4 1.9e-13 -0.62 0.25 0.45 TRUE