Best TWAS P=1.15e-17 · Best GWAS P=4.95e-20 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | EHBP1 | 0.08 | 0.02 | enet | 14 | 0.02 | 1.4e-02 | -7.1 | 8.6 | 1.2e-17 | -0.43 | 0.26 | 0.06 | TRUE |
| 6 | GTEx | Nerve Tibial | AC007098.1 | 0.05 | 0.02 | lasso | 5 | 0.02 | 2.1e-02 | -7.3 | -7.3 | 3.1e-13 | 0.72 | 0.25 | 0.17 | TRUE |
| 7 | GTEx | Thyroid | WDPCP | 0.07 | 0.03 | lasso | 6 | 0.06 | 2.1e-05 | 3.1 | 6.5 | 1.1e-10 | -0.48 | 0.15 | 0.84 | TRUE |
| 9 | METSIM | Adipose | WDPCP | 0.10 | 0.12 | blup | 488 | 0.15 | 5.4e-22 | 4.4 | 5.5 | 3.5e-08 | -0.46 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Colon Sigmoid | WDPCP | 0.15 | 0.05 | lasso | 4 | 0.03 | 3.0e-02 | 4.4 | 5.3 | 1.1e-07 | -0.49 | 0.37 | 0.30 | TRUE |
| 8 | GTEx | Whole Blood | WDPCP | 0.05 | 0.04 | lasso | 2 | 0.03 | 5.5e-04 | 5.2 | 5.2 | 1.5e-07 | -0.37 | 0.78 | 0.01 | TRUE |
| 3 | GTEx | Esophagus Mucosa | EHBP1 | 0.12 | 0.03 | enet | 20 | 0.05 | 2.6e-04 | -6.8 | 8.4 | 4.0e-17 | -0.51 | 0.36 | 0.06 | FALSE |
| 5 | GTEx | Nerve Tibial | EHBP1 | 0.09 | 0.02 | enet | 10 | 0.01 | 8.4e-02 | -6.7 | -6.2 | 7.7e-10 | 0.73 | 0.54 | 0.07 | FALSE |
| 4 | GTEx | Esophagus Mucosa | WDPCP | 0.06 | 0.03 | lasso | 3 | 0.04 | 1.7e-03 | 4.5 | 5.4 | 5.8e-08 | -0.40 | 0.49 | 0.17 | FALSE |