Hub : Genes

COLCA1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1430	0.0480	4.5e-04	0.053	NA	0.066	NA	0.083	3.7e-05	NA	4.6e-06	NA	2.5e-07
2	GTEx	Artery Aorta	0.1320	0.0510	5.3e-03	-0.005	NA	0.016	NA	-0.005	8.1e-01	NA	4.1e-02	NA	8.0e-01
3	GTEx	Cells EBV-transformed lymphocytes	0.4120	0.0840	1.5e-05	0.312	NA	0.266	NA	0.291	7.9e-11	NA	2.9e-09	NA	4.3e-10
4	GTEx	Colon Transverse	0.4180	0.0640	2.6e-12	0.290	NA	0.277	NA	0.292	3.0e-14	NA	1.4e-13	NA	2.4e-14
5	GTEx	Esophagus Muscularis	0.0870	0.0360	5.4e-03	0.045	NA	0.035	NA	0.038	9.5e-04	NA	3.3e-03	NA	2.2e-03
6	GTEx	Nerve Tibial	0.1824	0.0563	3.0e-04	0.035	NA	0.028	NA	0.032	1.5e-03	NA	4.4e-03	NA	2.3e-03
7	GTEx	Spleen	0.3330	0.1240	7.0e-03	0.224	NA	0.225	NA	0.217	2.0e-06	NA	1.8e-06	NA	2.9e-06
8	METSIM	Adipose	0.0758	0.0250	9.2e-06	0.005	0.031	0.016	0.033	0.018	5.7e-02	1.4e-05	1.4e-03	9.6e-06	9.0e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	0.9	2.7	-0.3	0.1	-0.4	-1.6	-0.6	1.4	-0.8	1.1
Bipolar Disorder or Schizophrenia	0.6	1.3	2.7	0.9	0.6	-1.4	-1.4	0.1	1.6	-1.6	0.6
Depressed Affect (Nagel 2018)	0.2	0.5	1.6	-0.2	0.3	0.1	1.1	-0.0	-0.6	0.6	1.3
Depression (Nagel 2018)	0.4	0.6	1.4	-0.9	-0.8	0.5	-0.0	-1.2	-0.6	1.0	-0.3
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.9	-0.5	-0.6	0.7	1.4	-0.9	-0.5	0.7	0.1
Neuroticism (Nagel 2018)	0.3	0.8	1.7	-0.9	-0.0	0.6	1.3	-1.0	-0.9	0.9	0.8
Schizophrenia (2018)	0.5	1.0	2.3	1.4	0.7	-1.4	-0.5	0.6	1.0	-1.5	-0.1
Schizophrenia vs Biploar Disorder	1.0	1.3	3.4	1.4	1.4	-0.5	-1.2	1.8	0.8	-0.6	0.8
Worry (Nagel 2018)	1.2	2.6	4.3	-1.6	-1.5	1.3	1.8	-1.8	-2.1	1.6	-0.8
Alzheimer’s Disease (in mother)	0.9	1.1	3.3	1.5	0.5	-1.8	-0.4	0.7	0.6	-1.3	0.3
Alzheimer’s Disease (in father)	1.3	1.4	3.7	-1.5	0.4	1.0	0.8	-1.5	-0.4	1.0	-1.9
Alzheimer’s Disease (including proxy)	0.3	0.4	1.8	-0.8	-0.1	0.2	0.1	-0.5	-0.2	0.6	-1.4
Crohns Disease (2017)	0.2	0.5	1.2	0.3	1.1	-0.5	-0.9	0.2	1.0	-0.3	0.8
Irritable Bowel Disease (IBD)	0.5	1.3	2.3	1.5	0.8	-1.3	-0.6	1.2	1.0	-0.7	1.4
Ulcerative Colitis (UC)	1.1	2.0	4.1	2.0	0.8	-1.6	-0.6	1.8	0.9	-1.0	1.8
Major Depression (MDD)	0.5	0.6	1.0	0.5	0.6	-1.0	-1.0	-0.3	0.9	-0.9	0.8
Reaction Time	0.7	1.2	2.5	-1.3	-1.3	1.6	0.1	-0.9	-0.6	1.6	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.6	3.3	0.2	-0.7	0.1	1.8	-0.4	-0.6	0.5	-0.3
Breast Cancer	1.2	2.8	6.9	-1.4	-0.2	1.4	2.6	-1.2	-2.6	1.2	1.3
Ovarian Cancer	0.3	0.3	1.0	0.4	0.9	-0.0	-1.0	0.5	0.2	-0.1	0.6
Prostate Cancer	0.1	0.1	0.6	-0.2	-0.8	-0.2	-0.0	-0.0	0.0	-0.1	0.7
Age at First Birth	0.3	0.4	1.5	-0.5	-0.7	0.5	-0.1	-0.6	-0.0	0.4	-1.2
Bipolar Disorder (2011)	0.2	0.2	0.6	-0.3	-0.8	0.1	-0.4	-0.4	0.1	-0.4	-0.2
Body Mass Index (BMI) (2010)	2.0	2.8	4.2	-1.6	-1.9	1.9	1.3	-1.3	-1.8	2.0	-1.4
Coronary Artery Disease (CAD)	2.1	2.5	6.0	2.4	-0.6	-2.1	-0.3	1.8	0.2	-1.2	2.0
Crohns Disease (2012)	1.3	2.2	7.2	0.4	1.9	-0.3	-2.7	1.0	1.9	-0.2	1.3
Mean Putamen Volume	0.2	0.3	0.8	0.4	-0.9	-0.6	0.0	0.2	0.0	-0.4	-0.9
Fasting Glucose	0.7	0.8	3.9	0.0	0.5	-0.4	2.0	-0.7	-1.4	-0.1	0.4
HbA1C	1.4	1.5	6.3	0.4	0.3	-0.3	2.5	0.2	-1.9	0.0	1.4
HDL Cholesterol	0.3	0.6	0.9	-0.9	0.8	0.7	0.6	-0.9	-0.9	0.6	0.1
LDL Cholesterol	3.2	5.1	8.5	2.9	0.8	-2.5	-1.5	2.7	2.4	-2.8	1.5
Lupus	1.8	2.7	5.1	2.1	1.0	-2.0	-0.4	1.7	1.0	-2.3	1.7
Neuroticism (2016)	0.1	0.2	0.8	0.2	-0.0	-0.0	0.3	0.3	-0.1	0.4	0.9
Primary Biliary Cirrhosis	0.9	1.3	4.2	-1.2	-2.1	1.1	0.3	-1.2	0.3	1.2	-0.6
Rheumatoid Arthritis	0.4	0.5	1.2	0.3	0.3	-1.0	-0.1	-1.1	0.8	-0.5	-0.8
Schizophrenia (2014)	0.4	1.0	2.3	0.8	0.7	-1.0	-1.5	-0.1	1.5	-1.1	0.2
Triglycerides	0.8	1.2	2.5	1.6	0.3	-1.4	-0.1	1.2	1.4	-1.3	-0.6
Type 2 Diabetes (T2D) (2012)	1.5	1.7	3.1	-0.3	-1.6	1.6	1.2	0.6	-1.4	1.8	-1.4
Ulcerative Colitis	0.8	1.2	2.1	1.4	0.7	-1.3	-0.8	1.3	0.7	-0.8	1.3
Blood Eosinophil Count	1.0	7.9	20.1	3.1	3.1	-3.3	-0.9	1.8	-0.1	-3.2	4.5
Blood Platelet Count	0.2	2.8	5.5	-1.6	-0.6	1.6	1.6	-1.5	-2.4	1.2	-2.2
Blood Red Count	0.8	7.9	28.8	0.9	-1.9	-2.6	-3.6	-1.1	5.4	-2.4	-1.8
Blood White Count	0.2	1.1	4.9	-0.3	-0.7	0.0	1.3	-0.7	-1.1	0.2	-2.2
Heel T-Score	0.5	3.8	8.6	2.8	-0.7	-2.5	-0.8	1.5	1.4	-2.9	1.4
BMI	0.1	0.4	2.0	-0.3	-0.8	0.3	-0.6	-0.1	0.6	0.3	-1.4
Height	0.2	4.7	16.6	1.2	0.4	-2.1	-3.2	0.3	4.1	-2.1	-0.5
Waist Hip Ratio (WHR)	1.3	5.8	13.5	2.9	-0.5	-3.7	-1.9	1.8	3.0	-2.7	1.2
Systolic Blood Pressure	0.4	2.2	8.5	-1.2	-2.9	1.7	-0.9	-0.6	-0.4	1.9	-0.2
Smoking Status	1.4	3.4	8.9	2.3	1.7	-3.0	0.2	0.8	0.4	-3.0	-0.7
Allergy or Eczema	0.4	1.0	2.1	-0.1	-0.1	-0.6	1.4	-1.1	-1.3	-0.6	-1.5
Cardiovascular Disease	0.7	2.4	5.9	-1.6	-2.3	2.0	-0.8	-1.0	0.0	2.4	-0.4
Hypothyroidism (self reported)	1.8	4.1	5.7	-2.3	-0.9	2.3	2.2	-2.4	-2.0	2.3	-1.0
Respiratory disease	0.5	1.1	2.8	0.5	0.7	-1.6	0.8	-1.1	-1.0	-1.7	-0.1
Type 2 Diabetes (T2D) (2018)	0.9	1.7	5.1	-0.8	1.2	0.1	1.9	-1.4	-2.3	0.1	-0.3
Lung FEV1/FVC ratio	0.1	0.4	1.6	0.5	-0.9	-0.1	-0.6	1.3	0.6	-0.2	0.0
Lung FVC	0.1	0.5	1.0	0.8	-0.2	-0.9	-0.5	1.0	0.9	-0.7	0.6
Neuroticism	0.2	0.5	2.7	0.1	0.8	-0.3	0.9	0.0	0.1	-0.0	1.6
Chronotype (morning person)	0.2	0.4	1.4	-0.7	-0.1	0.3	-0.1	-1.2	-0.1	0.4	1.0
Hair Pigment	0.0	0.8	2.3	-0.2	-1.4	0.4	1.2	-0.5	-1.5	0.4	-0.1
Tanning	0.1	1.2	3.7	0.2	1.3	-0.2	-1.9	0.3	1.5	-0.3	1.1
Hand grip strength (left)	0.5	1.4	5.1	0.3	-0.1	-0.6	-2.3	-0.3	2.1	-0.8	-0.5
Number of treatments/medications taken	0.2	0.4	1.8	0.6	-1.3	-0.7	-0.2	0.4	-0.2	-0.2	-0.1
Average weekly spirits intake	0.8	1.0	2.3	1.5	0.0	-1.1	-0.7	1.5	0.6	-1.0	0.5
Sensitivity / hurt feelings	0.8	1.4	7.6	0.4	2.8	-0.5	0.8	0.2	0.1	-0.3	1.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.5	-0.4	-0.6	-0.2	-0.2	-0.7	-0.7	0.2	-0.1
Hearing difficulty/problems: Yes	0.9	1.3	5.5	0.7	2.3	-0.6	1.1	0.7	-0.2	-0.1	1.5
Relative age of first facial hair	0.4	0.8	2.6	-0.6	1.6	-0.1	-0.1	-1.5	-0.8	0.5	0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	-0.3	-0.5	-0.0	-0.5	-0.4	-0.2	0.0	0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	0.5	0.6	-0.3	-0.3	0.2	-0.3	0.0	-0.1
Ever had hysterectomy (womb removed)	0.3	0.3	1.2	-0.2	0.1	0.2	0.5	-0.2	-1.1	0.1	-1.1
Systolic blood pressure, automated reading	0.4	1.2	4.1	-0.9	-2.0	0.9	0.2	-0.9	-0.7	1.2	-0.8
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	7.0	1.7	1.2	-0.9	-1.1	2.6	1.2	-1.1	0.7
Angina	0.9	1.2	4.9	-1.2	2.2	0.5	-0.9	-1.2	-0.3	0.6	0.3
Medication for hormone replacement therapy	0.4	0.5	1.9	0.2	0.5	-0.3	-1.4	0.3	0.7	-0.5	0.8
Vitamin and mineral supplements	0.4	0.5	1.2	0.3	-0.5	0.3	-1.0	1.1	0.8	0.8	-0.5
Supplements: Zinc	0.5	0.6	1.7	-0.8	-0.5	1.3	0.0	0.0	0.6	1.3	-0.0
Medication: Co-codamol	1.2	1.4	3.4	-1.0	-1.1	0.7	1.8	-1.0	-1.6	0.6	-1.0
Medication: Metformin	0.8	1.2	1.9	1.1	1.4	-1.2	-0.9	1.1	0.4	-1.0	1.4
Diabetes (father)	0.4	0.6	1.6	-0.5	1.2	0.8	0.6	0.1	-0.6	0.8	0.9
Diabetes (mother)	0.6	0.8	2.4	-0.5	0.5	-0.0	1.6	-1.1	-1.3	0.2	-0.7
Severe depression (siblings)	0.8	0.8	3.0	-0.7	-1.7	0.9	-0.7	-0.3	0.6	0.9	-0.8
Pack years adult smoking proportion	0.4	0.6	2.8	0.4	1.7	-0.7	-1.0	0.2	0.4	-0.5	0.5
Impedance of leg (right)	1.1	5.3	11.1	-3.3	-1.6	3.0	1.0	-2.7	-1.6	2.7	-1.4
Leg fat-free mass (left)	0.4	2.2	5.3	1.6	0.3	-1.5	-1.8	1.5	2.3	-1.5	-0.3
Trunk fat percentage	0.1	0.5	1.3	-0.4	-1.1	-0.3	-0.5	-0.7	0.5	-0.4	-1.1
Hand grip strength (right)	0.2	0.6	1.9	-0.1	-0.1	-0.2	-1.4	-0.8	1.0	-0.3	-0.8
Townsend deprivation index at recruitment	0.3	0.4	1.6	0.2	1.3	-0.4	-0.8	-0.0	0.7	-0.2	-0.1
Current tobacco smoking	0.8	1.2	2.9	1.2	1.7	-1.4	-0.1	0.5	0.7	-1.6	-0.4
Average weekly fortified wine intake	1.4	1.6	6.6	-0.9	0.6	1.3	2.6	-0.4	-1.2	1.2	-0.5
Maternal smoking around birth	2.1	3.0	8.7	1.2	1.9	-1.2	-2.9	1.7	2.0	-1.0	0.9
Fed-up feelings	0.4	0.8	2.3	-0.6	0.5	0.6	1.5	0.0	-1.3	0.9	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.1	0.8	0.4	-0.5	-0.6	1.0	0.3	-0.4	0.8
Relative age voice broke	0.2	0.2	1.3	-0.5	0.1	0.0	-0.3	-1.1	0.1	0.4	-0.3
Taking other prescription medications	0.4	0.5	2.1	-0.2	-0.5	-0.3	0.9	-0.7	-1.4	-0.2	-0.7
Age when periods started (menarche)	0.3	0.7	1.8	0.5	1.3	-0.8	-0.5	-0.2	0.3	-1.2	1.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.1	-1.4	-1.3	1.0	0.9	-1.3	-1.1	0.7	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.9	0.5	-1.4	-0.6	-0.9	-0.1	0.6	-1.0	-0.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	2.8	0.6	1.7	-0.7	1.0	0.2	-0.1	-1.0	0.4
Qualifications: CSEs or equivalent	0.4	0.6	3.7	-0.1	1.9	0.6	0.1	0.3	0.1	0.6	0.3
Serious illness, injury or assault to yourself	1.6	1.9	5.8	0.8	1.3	-1.4	-2.4	0.4	1.1	-1.5	1.2
High blood pressure	0.7	1.9	6.9	0.4	-2.6	0.3	-1.8	1.2	1.7	0.7	0.3
Hayfever, allergic rhinitis or eczema	0.4	0.9	3.4	-0.9	0.0	0.1	0.5	-1.5	-0.5	0.1	-1.8
Multivitamins +/- minerals	1.0	1.3	3.8	-0.4	2.0	-0.5	1.6	-1.4	-0.8	-0.7	0.8
Stomach or abdominal pain in last month	0.9	1.1	3.8	-0.2	0.1	-0.0	1.8	-0.7	-2.0	0.2	-1.3
Supplements: Glucosamine	1.2	1.6	4.7	-0.5	-1.8	0.6	1.8	-0.6	-2.2	0.5	-0.8
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	0.0	-0.6	-0.3	0.2	-0.3	0.2	-0.2	0.2
Medication: Atenolol	0.4	0.5	0.9	-0.3	-0.9	-0.5	-0.9	-1.0	0.9	-0.4	-0.2
Medication: Levothyroxine sodium	0.2	0.3	0.6	-0.6	0.5	0.4	0.8	-0.6	-0.8	0.4	-0.1
Sitting height	0.2	1.4	4.9	-0.0	0.4	-0.7	-1.6	-0.8	2.2	-1.0	-1.1
Chronic bronchitis/emphysema (father)	0.3	0.3	1.1	0.6	1.1	-0.6	0.3	0.1	-0.6	-0.4	-0.5
High blood pressure (mother)	1.2	1.7	4.3	-1.8	-0.0	2.1	0.4	-1.2	-1.0	1.9	0.2
Body mass index (BMI)	0.1	0.5	0.8	0.8	-0.6	-0.9	-0.4	0.7	0.6	-0.8	-0.7
Impedance of leg (left)	1.0	4.9	10.4	-3.2	-1.4	2.7	1.0	-2.9	-1.5	2.5	-1.3
Leg predicted mass (left)	0.4	2.2	5.2	1.6	0.2	-1.5	-1.8	1.5	2.3	-1.5	-0.4
Trunk fat mass	0.1	0.6	1.3	-0.1	-0.9	-0.5	-1.0	-0.3	1.1	-0.6	-1.1
Waist circumference	0.2	0.8	1.2	0.7	-1.0	-1.1	-0.4	0.5	1.0	-0.9	-1.1
Number of incorrect matches in round	1.0	1.7	4.1	-1.0	-1.6	0.9	1.4	-1.1	-2.0	0.5	-1.3
Past tobacco smoking	0.9	1.7	4.6	-1.9	-0.3	2.1	-0.2	-1.2	-0.2	2.0	0.3
Alcohol usually taken with meals	0.3	0.5	1.2	-0.4	-0.4	0.1	1.1	-1.0	-0.6	-0.3	1.0
Nervous feelings	0.3	0.6	1.5	-0.7	-0.2	0.9	1.0	-0.3	-1.2	0.9	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.2	-1.1	-0.4	1.2	-0.5	-0.6	-0.4	1.5	-0.0
Hearing difficulty/problems with background noise	0.6	0.9	3.7	0.1	1.0	0.3	1.1	0.4	-1.9	0.8	0.5
Hair/balding pattern: Pattern 2	2.6	3.3	5.1	-2.0	0.0	2.3	2.0	-1.4	-2.0	2.0	-1.6
Had menopause	0.4	0.6	1.9	0.7	1.4	-0.8	-0.5	0.2	0.0	-1.0	0.2
Had other major operations	1.1	1.3	5.4	0.3	-2.3	-0.6	1.0	-0.1	0.2	-0.8	-1.7
Forced vital capacity (FVC)	0.5	1.9	3.4	-1.5	-1.6	1.5	-0.3	-1.1	-0.5	1.8	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.4	-0.2	-0.8	-0.3	-0.4	-1.2	0.3	-0.6	-1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.6	-0.2	-1.3	1.0	0.1	0.7	-0.2	0.9	0.6
Qualifications: None of the above	0.7	1.6	3.6	1.5	0.8	-1.2	-1.4	1.9	0.6	-1.1	-1.0
Financial difficulties in last 2 years	0.1	0.2	0.7	0.6	-0.1	-0.4	-0.2	0.8	0.0	-0.4	-0.4
Mouth/teeth dental problems	0.4	0.7	1.4	-0.7	-1.2	0.9	-0.9	-0.4	0.6	1.1	0.1
Heart attack	1.4	1.8	4.7	-0.1	2.0	-0.8	-1.8	-0.6	1.2	-0.3	2.2
Allergy	0.4	0.9	2.2	0.1	-0.4	1.1	-0.5	1.4	0.3	1.1	1.5
Pain all over the body in last month	0.4	0.4	1.3	-0.3	-1.0	0.7	-0.2	0.4	-0.4	1.1	0.3
Diabetes (self-reported)	1.0	1.5	5.0	0.1	2.2	-0.6	1.4	-0.4	-2.0	-0.6	0.5
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.0	-0.3	-1.0	0.5	0.2	0.2	-1.6	0.7	-1.7
Medication: Ramipril	0.7	0.9	1.8	-0.9	0.1	1.2	1.4	-0.4	-0.9	1.2	0.3
Medication: Simvastatin	0.2	0.3	1.5	-0.5	-0.2	-0.1	0.1	-1.2	-0.4	0.4	-0.3
Fluid intelligence score	0.5	1.0	4.3	-0.3	-0.9	0.3	2.1	-1.2	-0.9	0.7	-0.5
Illnesses of siblings	0.4	0.5	1.2	0.5	0.3	-0.9	-0.3	-0.2	0.9	-1.1	0.8
Neuroticism score	0.3	0.6	2.2	0.5	0.3	-0.5	1.3	0.6	-0.2	-0.3	1.5
Weight	0.3	1.3	3.5	0.9	-0.4	-1.1	-1.5	0.6	1.9	-1.0	-0.8
Impedance of arm (right)	0.2	0.8	1.9	-1.1	-0.2	0.8	0.8	-1.3	-1.4	0.8	0.3
Arm fat percentage (right)	0.0	0.2	0.4	0.3	-0.6	-0.6	-0.1	-0.1	0.1	-0.6	-0.4
Trunk fat-free mass	0.4	2.4	6.5	1.5	0.3	-1.3	-2.1	1.5	2.5	-1.3	-0.4
Hip circumference	0.2	0.7	3.3	-0.2	-1.4	0.3	0.1	0.1	0.3	0.1	-1.8
Time employed in main current job	0.1	0.1	0.2	0.1	-0.3	-0.1	-0.3	0.5	0.3	0.3	0.2
Alcohol intake versus 10 years previously	0.4	0.6	1.9	0.2	1.4	0.1	1.0	0.0	-0.8	-0.5	-1.1
Father’s age at death	0.1	0.2	0.9	-0.3	0.4	0.1	1.0	-0.2	-0.1	-0.2	-0.5
Worrier / anxious feelings	0.9	1.6	3.5	-1.9	0.1	1.7	0.7	-1.4	-1.0	1.5	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.1	-1.0	-0.4	1.3	0.1	-0.2	0.3	1.8	-0.1
Falls in the last year	1.1	1.5	3.2	1.2	1.2	-1.4	-0.3	0.6	0.7	-1.8	1.6
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	0.8	-1.2	-0.8	-0.9	0.6	0.4	-0.1	0.9
Number of live births	2.0	2.8	5.0	2.0	1.8	-2.2	-0.4	0.8	1.4	-2.2	1.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	3.2	-1.1	-1.8	1.4	-1.1	-0.4	0.3	1.6	-1.1
Pulse rate	0.7	1.2	6.3	-0.6	-1.2	0.5	0.3	-0.4	-0.6	0.6	-2.5
Happiness	0.9	1.1	2.8	-0.6	-1.3	0.6	1.7	-0.8	-1.2	0.7	-0.7
Noisy workplace	0.1	0.1	0.3	-0.1	0.5	0.4	0.0	0.3	-0.2	0.5	0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.7	-0.5	-0.0	0.8	0.5	-0.1	-0.0	0.6	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.6	0.2	0.9	0.3	-0.3	0.6	0.4	0.4	1.3
Mouth/teeth dental problems: Dentures	0.8	1.3	2.4	1.1	1.5	-1.6	-1.3	0.8	0.4	-1.4	-0.5
Asthma	1.0	2.0	5.8	-1.4	-0.2	0.3	1.1	-2.4	-1.6	0.2	-2.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.3	-0.4	-0.6	1.1	1.2	0.0	-0.7	0.5	-1.0
Medication: Cholesterol lowering	0.2	0.4	1.5	-0.8	-0.1	-0.1	-0.6	-1.2	0.3	0.2	0.4
Depression (self-reported)	1.1	1.4	3.9	0.8	0.5	-1.0	-1.7	0.5	2.0	-1.1	0.9
Medication: Lansoprazole	0.1	0.1	0.4	0.0	-0.3	-0.5	0.7	-0.5	0.0	-0.1	0.3
Prospective memory result	0.2	0.2	0.7	0.6	0.7	-0.5	0.2	0.2	-0.3	-0.3	0.8
Lung cancer (father)	0.4	0.5	1.6	-0.7	1.3	0.2	-0.4	-0.8	-0.0	0.5	-0.7
Illnesses of mother	1.2	1.5	3.2	1.1	-1.4	-0.9	-1.5	1.2	1.8	-0.9	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.8	-1.1	-0.7	1.3	-1.3	-0.2	1.0	1.3	-0.6
Pulse wave Arterial Stiffness index	0.9	1.1	2.8	0.7	0.9	-1.0	-1.1	0.5	1.7	-0.8	1.1
Impedance of arm (left)	0.2	1.0	2.4	-1.3	-0.2	1.0	0.6	-1.5	-1.1	1.0	0.5
Arm fat mass (right)	0.1	0.5	0.9	0.5	-0.6	-0.7	-0.8	0.4	0.9	-0.7	-0.7
Trunk predicted mass	0.4	2.3	6.5	1.5	0.3	-1.3	-2.0	1.4	2.5	-1.3	-0.4
Standing height	0.1	1.4	6.1	0.1	0.3	-0.4	-2.2	-0.2	2.5	-0.3	-0.5
Length of working week for main job	0.6	0.6	1.9	-0.4	1.4	0.6	0.6	-0.2	-1.4	0.3	0.5
Exposure to tobacco smoke at home	1.2	1.3	3.9	1.2	0.5	-1.7	-0.7	0.4	1.2	-2.0	0.1
Breastfed as a baby	0.2	0.2	0.5	0.1	0.7	-0.4	0.1	-0.4	-0.3	-0.7	-0.4
Tense / ‘highly strung’	0.0	0.1	0.2	0.2	0.1	-0.5	0.1	0.2	0.2	-0.2	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.5	-0.3	0.2	0.7	0.3	-0.1	-0.1	0.4	-0.1
Hair/balding pattern: Pattern 4	0.2	0.4	1.7	0.2	-0.3	-0.4	-0.9	-0.1	1.3	-0.6	-0.0
Birth weight of first child	0.2	0.4	2.1	-0.9	-0.2	0.3	-0.3	-1.5	-0.3	0.0	-0.4
Peak expiratory flow (PEF)	0.6	1.3	5.7	-1.0	-2.4	0.4	-0.9	-1.1	0.8	0.6	-0.8
Pulse wave reflection index	1.0	1.2	4.6	-0.7	-0.1	0.1	-1.8	-0.8	2.2	0.0	0.8
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.7	1.6	1.1	-1.0	-0.3	1.9	0.3	-0.8	0.8
Loud music exposure frequency	0.4	0.4	1.1	0.9	1.0	-0.7	0.5	0.6	0.2	-0.4	0.7
Qualifications: O levels/GCSEs or equivalent	3.6	5.8	10.6	-2.9	-1.4	3.2	2.0	-1.7	-2.2	3.1	-1.9
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.1	-0.1	-1.4	0.5	1.4	0.1	-0.8	0.3	-0.2
Blood clot in the leg (DVT)	3.7	4.8	7.5	2.3	2.3	-2.7	-1.7	1.3	1.9	-2.7	2.1
Medication: Paracetamol	0.4	0.7	1.8	0.7	0.0	-0.9	-0.8	0.8	1.4	-0.6	1.1
Headache pain in last month	0.1	0.2	1.1	0.1	-1.1	-0.3	0.5	0.0	0.4	-0.2	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.2	0.4	1.1	-0.1	-0.5	0.8	0.4	-0.6	-0.1
Glaucoma (self-reported)	0.4	0.5	0.8	-0.5	0.9	0.6	0.7	-0.6	-0.8	0.8	0.6
Gout (self-reported)	0.6	0.8	5.6	-0.3	-2.4	0.3	-0.2	0.3	-0.0	0.6	-0.6
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	4.0	-1.8	-0.1	1.6	1.5	-2.0	-1.8	1.5	-0.5
Medication: Amlodipine	0.6	0.8	5.6	-0.1	-2.4	0.3	0.2	0.6	0.3	0.3	-0.5
Medication: Ventolin 100micrograms inhaler	1.3	1.7	4.6	-0.8	-1.3	1.0	1.0	-0.7	-1.8	0.8	-2.1
Birth weight	0.7	1.4	5.1	-0.8	0.8	-0.1	-2.3	-1.3	1.5	-0.8	-0.7
Chronic bronchitis/emphysema (mother)	1.0	1.1	5.2	-1.0	0.8	0.8	0.4	-0.7	-0.6	0.7	-2.3
High blood pressure (siblings)	1.1	1.5	3.8	-1.1	-1.1	1.5	0.8	-0.3	-1.7	1.9	-0.3
Forced vital capacity (FVC), Best measure	0.3	1.1	1.9	-1.3	-0.6	1.3	-1.1	-0.8	0.7	1.4	-1.0
Body fat percentage	0.1	0.5	1.4	-0.5	-1.2	-0.2	-0.1	-0.8	0.2	-0.3	-1.2
Leg fat percentage (right)	0.3	1.1	3.0	-1.1	-1.6	0.3	0.4	-1.3	-0.0	0.2	-1.7
Arm fat-free mass (right)	0.4	1.8	6.7	0.8	-0.1	-0.9	-1.9	0.9	2.6	-0.8	-1.0
Exposure to tobacco smoke outside home	0.2	0.2	1.2	0.0	1.1	-0.4	0.5	-0.4	-0.2	-0.1	-0.2
Comparative body size at age 10	0.2	0.5	1.4	0.7	1.2	-0.9	-0.5	0.7	0.3	-0.4	0.3
Number of full brothers	0.4	0.5	1.3	0.8	-0.1	-0.3	-1.1	1.2	0.1	-0.5	-0.3
Worry too long after embarrassment	0.6	1.1	2.4	1.1	0.5	-1.1	1.5	0.5	0.0	-1.0	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.2	-1.2	-0.6	1.8	1.3	-0.6	-0.8	1.3	-0.7
Wheeze or whistling in the chest in last year	1.4	2.5	4.5	-1.6	0.0	1.0	1.6	-1.9	-2.1	1.3	-2.1
Number of children fathered	0.5	0.6	2.0	0.1	-1.4	-0.4	-1.3	0.1	0.9	0.1	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.6	-0.5	-0.2	0.8	-0.2	0.4	-0.1	0.8	0.4
Age at first live birth	0.4	0.7	1.8	0.5	0.7	0.0	-0.8	0.9	1.1	0.1	1.3
Pulse wave peak to peak time	0.7	0.8	2.1	-0.6	-0.7	0.8	1.0	-0.5	-1.4	0.6	-1.1
Health satisfaction	0.6	0.7	1.8	1.4	-0.2	-1.3	0.0	1.1	-0.2	-1.0	0.3
Shortness of breath walking on level ground	1.3	1.5	2.4	1.6	0.9	-1.3	-0.8	1.5	0.8	-1.3	1.4
Qualifications: College or University degree	0.2	0.8	2.6	0.2	-1.6	0.4	-0.1	0.6	0.7	0.2	1.6
Eye problems/disorders: None of the above	0.7	0.8	2.0	-1.0	-0.8	0.5	0.9	-1.4	-0.8	0.2	-0.8
Mouth/teeth dental problems: Loose teeth	2.1	2.6	9.6	-0.9	-0.2	0.5	3.1	-1.8	-2.0	0.6	-1.5
Emphysema/chronic bronchitis	1.0	1.1	2.3	0.7	1.1	-1.3	-0.8	0.1	0.8	-1.5	1.3
Medication for pain relief, constipation, heartburn	0.4	0.6	1.3	-0.9	0.6	0.7	0.7	-1.1	-1.0	0.6	-0.5
Neck or shoulder pain in last month	0.7	1.0	2.6	0.9	1.5	-1.6	0.2	0.2	-0.6	-1.4	-0.4
Medication: Blood pressure	0.3	0.5	1.2	0.5	-0.9	-0.3	-0.7	0.8	1.1	-0.1	0.8
Angina (self-reported)	0.9	1.2	5.6	-1.1	2.4	0.5	-0.9	-1.1	-0.4	0.5	0.4
Migraine (self-reported)	0.6	0.8	1.8	-0.8	-1.3	0.6	-0.1	-0.7	0.5	1.2	-1.1
Medication: Ibuprofen	1.2	1.4	2.9	-0.7	-1.0	1.5	1.7	-0.1	-1.1	0.9	-1.7
Medication: Allopurinol	0.4	0.5	2.0	0.0	-1.4	0.2	-0.9	0.6	0.6	0.9	0.0
Medication: Omeprazole	2.5	3.0	4.6	2.1	0.1	-2.0	-1.9	1.8	2.1	-1.7	1.1
Medication: Seretide 50 evohaler	1.1	1.2	3.8	-0.9	-0.8	0.2	0.9	-1.5	-1.9	0.5	-1.2
Mean time to correctly identify matches	0.3	0.5	3.2	-0.3	-0.1	0.3	-0.8	-0.2	-0.1	0.4	1.8
Heart disease (mother)	0.2	0.3	0.8	0.4	0.2	-0.9	-0.1	-0.6	-0.2	-0.8	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.1	0.4	-0.0	-0.7	-1.0	-0.1	0.6	-0.4	-0.1
Whole body fat mass	0.1	0.5	1.2	0.1	-0.8	-0.6	-0.8	-0.1	1.0	-0.6	-1.1
Leg fat mass (right)	0.2	0.6	2.4	-0.5	-1.2	0.1	-0.4	-0.6	0.7	0.0	-1.6
Arm predicted mass (right)	0.3	1.4	5.7	0.6	-0.3	-0.6	-1.6	0.6	2.4	-0.6	-1.2
Pulse rate, automated reading	0.4	1.3	5.8	0.9	-0.4	-1.0	0.8	1.3	-0.1	-0.9	-2.4
Alcohol intake frequency.	0.4	0.9	2.9	0.5	1.7	-0.8	-0.8	0.0	0.2	-0.5	1.6
Comparative height size at age 10	0.7	3.7	6.3	2.2	1.2	-2.1	-1.9	2.0	2.2	-2.5	0.6
Number of full sisters	0.2	0.2	0.6	0.1	0.8	0.2	-0.3	0.5	0.1	0.6	-0.4
Suffer from ‘nerves’	0.4	0.6	2.1	0.3	-0.3	0.3	1.4	0.5	-1.4	-0.1	-0.6
Overall health rating	0.2	0.3	1.0	0.7	0.4	-1.0	0.5	0.2	-0.4	-0.7	0.1
Chest pain or discomfort	0.7	1.1	4.8	-1.5	0.8	0.6	0.1	-2.2	-0.5	0.7	-0.1
Had major operations	0.2	0.2	0.7	-0.3	0.8	0.0	0.2	-0.7	-0.3	0.3	-0.4
Age at last live birth	0.8	1.1	4.7	0.7	2.2	-0.6	-0.2	0.3	0.5	-0.5	1.6
Family relationship satisfaction	1.3	1.6	3.8	-1.3	-0.2	1.0	1.6	-1.9	-1.2	1.6	-0.1
Leg pain on walking	1.3	1.6	3.5	1.2	-1.6	-1.3	-1.9	1.1	1.1	-1.2	0.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	4.0	1.2	0.7	-1.8	0.3	-0.1	-0.1	-2.0	0.4
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.7	-0.8	0.7	0.3	-0.8	-0.7	-0.1	0.5	0.4
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	0.2	-0.5	-0.1	0.3	-0.1	0.4	-0.0	-0.3
Medication: Aspirin	0.3	0.4	1.0	0.7	0.4	-0.5	-0.6	1.0	0.4	-0.4	0.7
Supplements: Vitamin C	0.3	0.3	1.7	-0.3	-0.7	0.0	-1.3	-0.4	0.2	-0.2	-0.0
Knee pain experienced in last month	0.4	0.6	2.1	0.8	-0.4	-1.0	-0.7	0.3	0.2	-1.4	-0.7
Hypertension (Self-reported)	0.6	1.7	7.3	0.1	-2.7	0.5	-1.7	0.9	1.3	0.9	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.8	1.3	0.3	-0.9	-0.5	1.7	0.6	-1.1	1.0
Illnesses of father: Heart disease	0.7	1.0	3.2	1.1	-0.6	-0.5	-0.7	1.8	0.7	-0.0	1.4
Illnesses of siblings: Diabetes	1.0	1.2	4.9	-0.6	-0.1	1.3	0.8	0.4	-0.8	1.2	-2.2
Smoking status: Previous	0.7	1.0	2.9	1.3	-0.4	-1.7	0.4	0.3	-0.1	-1.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	4.5	0.4	-1.0	0.2	-2.1	1.5	1.2	0.2	-1.0
Whole body fat-free mass	0.4	2.2	6.0	1.5	0.2	-1.4	-1.9	1.4	2.5	-1.3	-0.6
Leg fat-free mass (right)	0.5	2.5	5.3	1.8	0.4	-1.7	-1.9	1.5	2.3	-1.6	-0.3
Arm fat percentage (left)	0.0	0.2	0.5	0.1	-0.7	-0.5	-0.0	-0.3	0.2	-0.5	-0.4
Average weekly red wine intake	0.2	0.4	1.5	0.4	-0.6	-0.3	-1.2	0.3	0.6	-0.4	0.5
Handedness (chirality/laterality): Left-handed	1.9	2.3	4.2	-1.8	0.0	2.1	1.4	-0.9	-1.6	2.0	-1.1
Mood swings	0.2	0.4	1.9	0.1	0.8	-0.0	0.5	0.8	-0.1	0.3	1.4
Loneliness, isolation	1.6	2.2	3.8	1.9	0.8	-1.8	-0.3	1.8	0.9	-1.4	1.9
Long-standing illness, disability or infirmity	0.5	0.7	1.4	0.7	1.1	-1.2	0.7	-0.4	-0.7	-1.1	0.5
Ever had bowel cancer screening	1.9	2.3	9.5	1.0	1.5	-1.3	-1.3	0.5	0.5	-1.1	3.1
Diabetes diagnosed by doctor	0.9	1.4	4.1	0.3	2.0	-0.8	1.5	-0.5	-1.7	-0.8	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.4	1.1	-0.4	-1.1	1.1	0.5	0.3	-1.2	0.3
Friendships satisfaction	1.6	1.9	3.3	-1.1	-1.6	1.8	1.8	-0.4	-1.2	1.7	-0.4
Qualifications: nursing, teaching	0.1	0.2	0.7	0.4	0.1	0.1	0.1	0.8	0.0	0.1	0.9
Commuting to job workplace: Walk	0.3	0.3	2.2	0.1	0.3	-0.2	1.5	-0.4	-0.4	-0.2	0.1
Eye problems/disorders: Cataract	1.8	2.1	4.3	1.9	1.3	-1.5	-0.9	2.1	0.6	-0.6	1.9
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.1	1.0	1.8	-0.7	0.1	1.3	0.7	-1.0	1.5
Medication for cholesterol	0.2	0.3	0.7	0.2	0.9	0.3	0.8	0.3	-0.6	0.4	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	0.1	-0.7	-0.0	-0.5	0.3	0.2	0.9	0.2
Back pain experienced in last month	0.5	0.8	2.5	-0.9	0.9	0.2	0.8	-1.6	-0.6	0.6	-0.9
Mineral and other dietary supplements	0.2	0.2	1.2	0.0	1.1	-0.0	-0.4	-0.1	0.4	0.5	-0.2
Breast cancer (self-reported)	0.5	0.6	2.7	-0.4	1.6	0.6	-0.8	0.3	0.2	0.7	0.1
Asthma (self-reported)	1.0	1.9	5.0	-1.3	-0.7	0.3	1.1	-2.2	-1.8	0.2	-1.9
Osteoporosis (self-reported)	0.9	1.2	4.7	0.5	2.2	-0.5	-1.3	0.6	0.4	-0.7	1.2
Osteoarthritis (self-reported)	2.1	2.7	9.9	-1.1	-1.8	1.0	1.9	-0.9	-1.1	0.9	-3.1
Medication: Aspirin	0.7	0.9	2.0	0.9	0.1	-0.5	-1.4	1.4	1.0	-0.5	1.0
Medication: Gliclazide	0.9	1.0	1.7	0.9	0.2	-1.2	-1.1	0.2	1.0	-1.3	1.3
Illnesses of father: None of the above (group 1)	0.8	1.0	2.5	0.5	1.6	-0.9	-0.9	-0.6	1.1	-1.1	0.8
Smoking status: Current	0.8	1.3	3.4	1.1	1.5	-1.5	0.1	0.3	0.8	-1.9	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.3	-1.2	-0.9	1.2	0.9	-0.5	-0.4	1.8	-1.3
Whole body water mass	0.4	2.4	6.3	1.6	0.3	-1.4	-2.0	1.5	2.5	-1.4	-0.5
Leg predicted mass (right)	0.5	2.5	5.3	1.8	0.3	-1.7	-1.9	1.5	2.3	-1.6	-0.3
Arm fat mass (left)	0.1	0.4	0.9	0.4	-0.6	-0.6	-0.6	0.2	0.9	-0.6	-0.7
Number of self-reported non-cancer illnesses	0.3	0.5	1.7	-0.1	-0.8	-0.5	0.4	-0.6	-1.3	0.2	-0.8
Average weekly champagne plus white wine intake	0.3	0.4	1.2	0.4	-1.1	-0.4	-0.3	0.5	0.4	-0.0	0.9
Miserableness	0.4	0.8	3.5	-0.2	0.1	0.5	0.9	0.5	-0.5	0.9	1.9
Guilty feelings	0.2	0.2	1.2	-0.0	-1.1	-0.1	-0.0	0.0	0.6	-0.2	-0.5
Wears glasses or contact lenses	0.2	0.2	0.7	-0.2	-0.3	-0.4	0.8	-0.8	-0.7	-0.0	0.1
Ever taken oral contraceptive pill	0.6	0.7	2.9	0.7	0.4	0.5	0.4	1.7	-0.3	0.7	1.0
Hearing aid user	4.3	4.8	11.0	3.3	2.2	-2.8	0.6	2.8	0.1	-2.1	1.6
Mother’s age at death	0.4	0.5	2.7	0.2	-1.6	-0.1	-0.5	0.6	0.2	-0.2	-0.6
Financial situation satisfaction	0.3	0.4	0.8	-0.4	-0.9	0.1	0.7	-0.7	-0.5	0.2	-0.8
Tinnitus: Yes, now most or all of the time	1.3	1.5	4.5	0.5	-0.9	-1.1	-2.0	-0.4	2.1	-1.2	0.1
Commuting to job workplace: Public transport	1.2	1.4	3.7	-1.0	-0.4	1.6	1.2	-0.4	-1.3	1.9	-0.9
Eye problems/disorders: Glaucoma	0.5	0.6	1.8	-0.2	0.6	0.5	1.2	-0.1	-1.3	0.6	0.6
Medication: Blood pressure	0.2	0.3	1.8	-0.1	-1.3	-0.1	0.5	-0.3	-0.4	0.2	-0.3
Pain type(s) experienced in last month: Hip pain	0.4	0.6	1.7	-0.7	-1.1	-0.1	0.6	-1.3	-0.5	0.1	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.2	0.2	1.0	-0.6	0.4	-0.2	-0.1	-1.0	1.1
High cholesterol (Self-reported)	0.3	0.5	1.1	-0.8	-0.3	0.4	-0.7	-0.8	0.1	0.7	-1.0
Medication: Bendroflumethiazide	0.2	0.2	0.8	0.7	-0.4	-0.5	0.9	0.4	-0.1	-0.1	0.3
Medication: Paracetamol	0.2	0.3	1.2	0.3	-0.3	-0.1	-0.0	1.1	0.6	0.1	0.6
Medication: Lisinopril	1.8	2.4	5.9	2.2	0.6	-1.7	-0.6	2.4	0.6	-1.5	1.4
Medication: Atorvastatin	1.0	1.2	3.2	0.9	1.6	-1.6	-0.6	-0.2	0.7	-1.8	0.2
Illnesses of father: High blood pressure	0.9	1.1	2.2	-1.0	-0.1	1.3	1.5	-0.4	-1.3	1.1	0.7
Alcohol drinker status: Never	0.5	0.6	1.3	-0.9	0.9	1.0	0.1	-0.3	-1.0	1.1	-0.0
Ever smoked	1.1	2.0	3.9	2.0	1.6	-1.8	0.4	1.6	-0.4	-1.8	-0.6
Basal metabolic rate	0.4	2.2	6.1	1.4	0.0	-1.3	-2.0	1.4	2.5	-1.3	-0.6
Leg fat percentage (left)	0.3	0.9	2.7	-0.8	-1.4	-0.1	0.3	-1.3	0.2	-0.1	-1.6
Arm fat-free mass (left)	0.3	1.6	4.7	0.9	-0.1	-0.9	-1.6	0.9	2.2	-1.0	-1.3
Number of operations (self-reported)	0.6	0.9	3.0	-0.5	-1.4	-0.4	0.5	-1.3	-0.0	-0.4	-1.7
Average weekly beer plus cider intake	0.4	0.6	1.4	-1.1	0.3	0.7	-0.7	-1.2	-0.4	1.1	-0.1
Irritability	0.3	0.5	1.2	0.2	0.2	-0.1	-1.0	0.4	1.1	0.2	1.1
Risk taking	1.3	1.9	3.1	1.8	-0.3	-1.5	-1.3	1.7	1.4	-1.3	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.8	-0.8	1.1	-0.1	0.3	-1.3	-0.1	-0.2	1.0
Fractured/broken bones in last 5 years	1.3	1.7	3.9	1.0	0.6	-1.8	-1.3	-0.3	2.0	-1.8	0.4
Age started oral contraceptive pill	2.2	2.8	4.8	2.2	1.9	-1.6	0.9	1.9	1.2	-2.0	1.0
Diastolic blood pressure, automated reading	0.3	0.9	4.5	-0.8	-2.1	0.7	-0.4	-0.9	0.1	0.9	-0.3
Ever depressed for a whole week	0.6	0.7	2.5	1.1	-0.1	-0.4	0.6	1.6	0.0	-0.5	0.9
Unable to work because of sickness or disability	0.6	0.8	1.2	1.0	-0.6	-1.0	-1.1	0.8	1.0	-1.1	-0.1
Commuting to job workplace: Cycle	3.8	4.6	8.4	2.4	-0.0	-2.3	-2.2	2.1	2.9	-2.5	1.4
Myopia	0.2	0.4	1.4	0.4	-0.1	0.0	0.5	0.7	-0.8	0.2	1.2
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.6	0.2	1.9	-0.5	1.4	-0.3	-1.2	-1.0	-0.3
Cholesterol lowering medication	0.3	0.5	1.5	0.0	1.2	-0.6	-0.0	-0.9	-0.1	-0.3	-1.1
Medication: Omeprazole (e.g. Zanprol)	3.2	3.8	6.6	2.4	0.6	-2.6	-2.1	1.6	2.0	-2.4	1.1
Pain experienced in last month	0.3	0.5	1.3	-0.8	0.6	1.0	0.2	-0.3	-0.1	1.2	0.7
Supplements: Calcium	0.4	0.5	1.6	-0.2	-1.3	0.2	0.1	-0.6	0.3	-0.6	-1.1
Basal cell carcinoma (self-reported)	0.2	0.2	0.8	0.1	-0.1	0.1	0.4	0.7	-0.9	0.3	-0.1
Heart attack/myocardial infarction (self-reported)	1.4	1.9	5.3	-0.2	1.9	-0.8	-1.8	-0.8	1.2	-0.3	2.3
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	6.3	2.0	2.0	-2.5	-1.4	0.8	1.6	-2.4	1.8
Heart disease (siblings)	0.4	0.5	1.4	0.5	1.2	-0.9	0.4	-0.4	-1.0	-0.5	-0.4
Alcohol drinker status: Previous	0.5	0.5	0.8	0.8	0.4	-0.8	-0.7	0.5	0.9	-0.7	0.7
Pack years of smoking	0.8	1.1	3.7	0.7	1.9	-1.2	-1.1	0.3	0.5	-0.9	0.9
Impedance of whole body	0.4	2.3	5.8	-2.3	-0.8	1.7	0.7	-2.4	-1.1	1.4	-0.4
Leg fat mass (left)	0.1	0.6	2.0	-0.3	-1.1	-0.2	-0.5	-0.5	0.8	-0.2	-1.4
Arm predicted mass (left)	0.3	1.7	4.6	1.2	-0.2	-1.1	-1.5	1.1	2.1	-1.2	-1.3