[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr20:29,833,609-32,083,711

Best TWAS P=6.29e-12 · Best GWAS P=4.43e-15 conditioned to 4.98e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNMT3B 0.04 0.05 lasso 2 0.05 1.4e-06 5.9 6.0 2.1e-09 0.36 0.97 0.01 FALSE
2 GTEx Brain Caudate basal ganglia COX4I2 0.24 0.03 lasso 6 0.05 1.1e-02 -5.3 -5.3 1.0e-07 -0.03 0.04 0.84 FALSE
3 GTEx Cells Transformed fibroblasts HM13-AS1 0.04 0.01 lasso 3 0.01 1.0e-01 -5.4 5.1 2.9e-07 -0.02 0.03 0.86 FALSE
4 GTEx Colon Transverse DNMT3B 0.21 0.06 lasso 7 0.07 3.0e-04 4.3 5.1 2.9e-07 0.53 0.54 0.22 FALSE
5 GTEx Colon Transverse COMMD7 0.16 0.01 lasso 5 0.00 2.5e-01 5.9 6.9 6.3e-12 0.63 0.19 0.57 TRUE
6 GTEx Muscle Skeletal COMMD7 0.14 0.13 lasso 2 0.12 7.5e-12 5.4 5.4 6.5e-08 0.73 0.99 0.01 FALSE
7 GTEx Testis COMMD7 0.11 0.01 lasso 4 0.01 1.3e-01 5.4 6.2 5.8e-10 0.48 0.08 0.48 FALSE
8 GTEx Whole Blood HM13 0.05 0.05 lasso 4 0.05 1.4e-05 -5.4 -5.4 5.2e-08 0.00 0.03 0.97 TRUE
9 NTR Blood C20orf160 0.01 0.00 bslmm 305 0.00 8.0e-03 -4.2 5.1 3.1e-07 0.09 0.04 0.34 FALSE
10 NTR Blood HM13 0.03 0.05 lasso 6 0.05 2.2e-15 -5.3 -5.4 6.5e-08 0.00 0.03 0.97 FALSE
11 ROSMAP Brain Pre-frontal Cortex COMMD7 0.15 0.09 lasso 4 0.12 8.9e-16 4.7 5.9 3.8e-09 0.59 0.99 0.01 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HM13 0.06 0.03 blup 48 0.07 3.0e-08 -5.4 -5.2 1.7e-07 -0.02 0.03 0.97 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma COX4I2 0.04 0.06 enet 6 0.05 9.8e-07 -5.3 -5.3 1.3e-07 0.01 0.01 0.99 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma COMMD7 0.04 0.01 blup 48 0.03 9.9e-04 5.4 6.3 3.6e-10 0.63 0.26 0.46 FALSE