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chr20:33,110,042-34,829,868

Best TWAS P=3.03e-10 · Best GWAS P=4.7e-09 conditioned to 0.732

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	UQCC	0.07	0.04	lasso	2	0.05	1.4e-06	5.6	-5.6	1.8e-08	-0.84	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	UQCC1	0.09	0.12	lasso	2	0.11	4.5e-09	5.5	-5.5	3.6e-08	-0.84	0.04	0.96	FALSE
3	GTEx	Adipose Visceral Omentum	UQCC1	0.15	0.08	lasso	7	0.07	1.6e-04	5.5	-5.8	7.7e-09	-0.92	0.04	0.95	FALSE
4	GTEx	Adrenal Gland	MMP24-AS1	0.18	0.04	enet	10	0.13	2.2e-05	5.6	-5.7	1.1e-08	-0.82	0.03	0.90	FALSE
5	GTEx	Brain Cortex	ERGIC3	0.15	-0.01	lasso	6	0.00	2.8e-01	3.5	5.2	1.9e-07	0.77	0.05	0.61	FALSE
6	GTEx	Brain Frontal Cortex BA9	UQCC1	0.16	0.07	lasso	3	0.08	3.7e-03	5.6	-5.2	2.5e-07	-0.84	0.05	0.63	FALSE
7	GTEx	Breast Mammary Tissue (Male)	UQCC1	0.06	0.04	lasso	1	0.02	1.4e-01	5.7	-5.7	9.8e-09	-0.84	0.03	0.23	FALSE
8	GTEx	Cells Transformed fibroblasts	UQCC1	0.23	0.24	lasso	8	0.25	9.4e-19	5.5	-5.7	1.3e-08	-0.90	0.04	0.96	FALSE
9	GTEx	Esophagus Mucosa	UQCC1	0.13	0.10	enet	10	0.07	1.1e-05	5.7	-5.5	2.9e-08	-0.75	0.03	0.97	FALSE
10	GTEx	Lung	UQCC1	0.13	0.08	lasso	5	0.06	1.0e-05	5.5	-5.7	1.6e-08	-0.86	0.04	0.96	FALSE
11	GTEx	Muscle Skeletal	UQCC1	0.10	0.04	enet	19	0.05	1.3e-05	5.7	-6.3	3.0e-10	-0.91	0.02	0.98	TRUE
12	GTEx	Muscle Skeletal	CEP250	0.09	0.04	lasso	9	0.07	3.6e-07	4.7	-5.7	1.5e-08	-0.82	0.14	0.86	FALSE
13	GTEx	Nerve Tibial	UQCC1	0.07	0.04	enet	6	0.03	2.7e-03	5.5	-5.8	5.5e-09	-0.93	0.03	0.96	FALSE
14	METSIM	Adipose	UQCC1	0.09	0.04	enet	18	0.05	1.5e-07	5.5	-5.5	2.9e-08	-0.84	0.04	0.96	FALSE
15	NTR	Blood	UQCC	0.01	0.01	enet	6	0.00	1.6e-02	5.5	-5.4	8.2e-08	-0.83	0.03	0.92	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	UQCC1	0.05	0.05	lasso	5	0.06	1.7e-08	5.7	-5.4	8.8e-08	-0.72	0.03	0.97	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	GDF5	0.10	0.13	lasso	2	0.12	2.9e-15	5.5	5.5	3.3e-08	0.84	0.04	0.96	FALSE
18	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UQCC	0.03	0.04	blup	67	0.03	2.6e-03	5.5	-5.9	3.6e-09	-0.84	0.03	0.84	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	UQCC	0.08	0.11	blup	67	0.12	1.1e-22	5.7	-5.5	4.9e-08	-0.89	0.03	0.97	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UQCC	0.05	0.06	blup	66	0.06	3.6e-07	5.7	-5.9	3.8e-09	-0.89	0.03	0.97	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UQCC	0.09	0.10	blup	67	0.10	7.2e-11	5.5	-5.4	5.6e-08	-0.88	0.04	0.96	FALSE
22	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UQCC	0.08	0.01	lasso	3	0.01	9.0e-02	5.7	-5.5	4.0e-08	-0.90	0.02	0.93	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	UQCC	0.04	0.06	lasso	6	0.05	2.3e-06	5.5	-5.5	3.2e-08	-0.84	0.03	0.97	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	UQCC	0.10	0.07	enet	10	0.07	1.5e-08	5.7	-5.4	6.0e-08	-0.79	0.03	0.97	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	GDF5	0.05	0.02	blup	76	0.04	1.4e-03	5.5	5.5	5.0e-08	0.74	0.04	0.91	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UQCC	0.22	0.21	lasso	7	0.18	1.9e-07	5.4	-5.5	2.9e-08	-0.85	0.03	0.97	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	UQCC	0.07	0.10	lasso	8	0.11	1.3e-11	5.5	-5.6	2.6e-08	-0.83	0.04	0.96	FALSE
28	The Cancer Genome Atlas	Soft Tissue Sarcoma	UQCC	0.07	0.06	blup	66	0.07	5.2e-05	5.5	-5.9	4.5e-09	-0.84	0.03	0.96	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	GDF5	0.09	0.04	enet	13	0.05	2.4e-04	5.6	5.2	2.3e-07	0.52	0.05	0.87	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	UQCC	0.07	0.06	lasso	10	0.06	2.8e-05	5.6	-5.6	1.7e-08	-0.88	0.03	0.96	FALSE
31	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CEP250	0.10	0.00	blup	43	0.05	9.8e-03	5.7	5.8	5.3e-09	0.84	0.01	0.49	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	CEP250	0.05	0.03	blup	43	0.04	5.8e-05	4.7	5.2	1.9e-07	0.64	0.19	0.73	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	GDF5	0.02	0.00	blup	76	0.00	1.9e-01	5.7	5.7	1.6e-08	0.86	0.02	0.86	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	UQCC	0.15	0.21	blup	67	0.22	1.2e-20	5.7	-6.0	2.4e-09	-0.89	0.03	0.97	FALSE
35	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	UQCC	0.13	0.15	lasso	1	0.11	7.1e-04	5.7	-5.7	1.5e-08	-0.95	0.02	0.84	FALSE