TWAS hub - UQCC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0930	0.0360	4.9e-05	0.116	NA	0.090	NA	0.107	9.6e-10	NA	8.6e-08	NA	4.5e-09
2	GTEx	Adipose Visceral Omentum	0.1540	0.0800	5.9e-03	0.080	NA	0.054	NA	0.071	6.1e-05	NA	8.4e-04	NA	1.6e-04
3	GTEx	Brain Frontal Cortex BA9	0.1576	0.0798	3.9e-03	0.070	NA	0.075	NA	0.081	6.4e-03	NA	4.9e-03	NA	3.7e-03
4	GTEx	Breast Mammary Tissue	0.0970	0.0390	1.4e-04	0.059	NA	0.071	NA	0.082	5.5e-04	NA	1.6e-04	NA	5.3e-05
5	GTEx	Breast Mammary Tissue (Male)	0.0633	0.0692	1.7e-01	0.044	NA	0.010	NA	0.015	3.5e-02	NA	1.9e-01	NA	1.4e-01
6	GTEx	Breast Mammary Tissue (Female)	0.1253	0.0668	1.0e-02	0.028	NA	-0.008	NA	0.026	5.1e-02	NA	6.4e-01	NA	5.5e-02
7	GTEx	Cells Transformed fibroblasts	0.2280	0.0520	1.1e-14	0.237	NA	0.242	NA	0.250	9.5e-18	NA	3.9e-18	NA	9.4e-19
8	GTEx	Colon Transverse	0.1070	0.0490	4.2e-03	0.007	NA	0.000	NA	0.010	1.5e-01	NA	3.1e-01	NA	1.0e-01
9	GTEx	Esophagus Mucosa	0.1290	0.0560	5.8e-05	0.105	NA	0.074	NA	0.073	1.6e-07	NA	1.1e-05	NA	1.4e-05
10	GTEx	Lung	0.1272	0.0445	1.9e-05	0.081	NA	0.042	NA	0.065	8.3e-07	NA	3.3e-04	NA	1.1e-05
11	GTEx	Muscle Skeletal	0.0963	0.0361	7.3e-05	0.044	NA	0.049	NA	0.041	3.3e-05	NA	1.2e-05	NA	6.0e-05
12	GTEx	Nerve Tibial	0.0665	0.0341	4.3e-03	0.036	NA	0.031	NA	0.030	1.4e-03	NA	2.7e-03	NA	3.3e-03
13	GTEx	Skin Sun Exposed Lower leg	0.1890	0.0600	5.9e-08	0.130	NA	0.102	NA	0.102	6.3e-11	NA	8.1e-09	NA	8.1e-09
14	GTEx	Stomach	0.0850	0.0500	7.2e-03	0.135	NA	0.140	NA	0.146	5.2e-07	NA	3.4e-07	NA	1.8e-07
15	GTEx	Thyroid	0.1330	0.0660	1.6e-03	-0.002	NA	0.020	NA	0.002	4.5e-01	NA	1.0e-02	NA	2.1e-01
16	METSIM	Adipose	0.0914	0.0338	1.7e-07	0.044	0.040	0.046	0.043	0.044	2.8e-07	1.2e-06	1.5e-07	4.6e-07	3.4e-07
17	ROSMAP	Brain Pre-frontal Cortex	0.0541	0.0231	5.3e-05	0.051	0.052	0.059	0.054	0.063	3.9e-07	2.4e-07	4.3e-08	1.7e-07	1.7e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Sitting height	99.8	708.4	954.8	-29.9	-28.4	-26.9	-23.2	-30.0	-4.6	-28.9	-20.4	-30.9	-29.7	-26.5	-28.7	-29.3	-28.9	-10.5	-29.8	-29.2
Standing height	79.6	789.5	1061.8	-31.9	-30.2	-28.5	-24.5	-32.1	-5.8	-30.8	-19.1	-32.6	-31.8	-26.7	-30.6	-30.8	-31.0	-9.5	-31.9	-31.1
Height	77.9	1501.8	1989.2	-43.9	-41.7	-40.0	-34.4	-44.0	-8.7	-42.4	-27.4	-44.6	-43.8	-36.4	-42.2	-42.4	-42.5	-12.4	-43.9	-42.7
Comparative height size at age 10	72.8	400.8	529.0	-22.8	-21.9	-20.7	-17.3	-23.0	-3.4	-22.1	-13.8	-22.6	-23.0	-19.3	-22.5	-21.4	-21.8	-5.9	-22.5	-21.8
Trunk predicted mass	70.2	401.5	524.4	-22.6	-21.5	-21.3	-16.6	-22.6	-2.4	-21.8	-14.9	-22.9	-22.5	-19.9	-21.8	-22.2	-21.8	-8.1	-22.3	-21.8
Trunk fat-free mass	70.1	402.5	529.0	-22.6	-21.5	-21.2	-16.7	-22.6	-2.6	-21.9	-15.0	-23.0	-22.5	-19.9	-21.8	-22.2	-21.8	-8.2	-22.3	-21.9
Whole body fat-free mass	66.6	380.6	492.8	-22.0	-21.0	-20.7	-16.0	-22.0	-2.0	-21.3	-14.5	-22.2	-21.9	-19.5	-21.3	-21.5	-21.2	-8.2	-21.7	-21.3
Whole body water mass	64.9	370.4	479.6	-21.7	-20.7	-20.5	-15.7	-21.7	-1.8	-21.0	-14.3	-21.9	-21.7	-19.3	-21.0	-21.2	-20.9	-7.9	-21.4	-21.0
Leg predicted mass (right)	61.2	326.7	420.2	-20.5	-19.6	-19.2	-14.2	-20.4	-1.0	-19.9	-13.0	-20.5	-20.5	-18.3	-20.0	-19.7	-19.7	-7.3	-20.1	-19.7
Leg fat-free mass (right)	61.1	326.3	420.2	-20.5	-19.6	-19.2	-14.2	-20.4	-1.0	-19.8	-13.0	-20.5	-20.5	-18.3	-20.0	-19.7	-19.6	-7.3	-20.1	-19.7
Basal metabolic rate	58.9	326.2	420.2	-20.3	-19.4	-19.3	-14.9	-20.3	-1.8	-19.7	-13.8	-20.5	-20.3	-18.1	-19.8	-19.9	-19.5	-7.5	-20.0	-19.6
Leg predicted mass (left)	58.7	310.8	396.0	-19.9	-19.1	-18.7	-14.1	-19.9	-1.3	-19.3	-13.1	-19.9	-19.9	-17.9	-19.5	-19.2	-19.1	-7.4	-19.6	-19.2
Leg fat-free mass (left)	58.6	310.5	396.0	-19.9	-19.0	-18.7	-14.2	-19.8	-1.4	-19.3	-13.2	-19.9	-19.9	-17.9	-19.5	-19.2	-19.1	-7.4	-19.6	-19.1
Arm predicted mass (left)	55.6	282.5	364.8	-18.9	-18.0	-18.1	-14.0	-18.8	-1.8	-18.2	-13.0	-19.1	-18.8	-16.9	-18.3	-18.7	-18.0	-7.1	-18.5	-18.3
Arm fat-free mass (right)	55.2	283.2	368.6	-18.9	-17.9	-18.4	-14.0	-18.9	-1.5	-18.1	-12.6	-19.2	-18.8	-16.7	-18.2	-18.9	-18.3	-7.2	-18.6	-18.3
Arm predicted mass (right)	55.2	282.2	366.8	-18.9	-18.0	-18.4	-13.7	-18.9	-1.1	-18.1	-12.5	-19.2	-18.9	-16.8	-18.2	-18.7	-18.3	-7.0	-18.5	-18.2
Arm fat-free mass (left)	54.8	278.0	359.2	-18.8	-17.9	-17.9	-13.9	-18.7	-1.9	-18.1	-12.8	-19.0	-18.7	-16.6	-18.1	-18.5	-18.1	-7.1	-18.4	-18.1
Hand grip strength (right)	43.1	117.1	148.8	-11.9	-11.3	-10.4	-10.4	-12.0	-3.9	-11.8	-8.6	-12.2	-11.9	-10.4	-11.5	-12.0	-11.7	-5.7	-12.0	-12.0
Forced expiratory volume in 1-second (FEV1), predicted	35.1	72.9	104.6	-9.6	-9.4	-8.4	-6.8	-9.9	-0.3	-9.2	-6.5	-10.0	-9.6	-8.8	-9.4	-8.7	-8.9	-2.4	-9.6	-10.2
Hand grip strength (left)	34.7	91.6	116.6	-10.5	-10.0	-8.4	-9.5	-10.5	-4.0	-10.4	-7.8	-10.8	-10.5	-9.1	-10.2	-10.7	-10.3	-5.4	-10.7	-10.6
Weight	31.0	152.4	191.3	-13.8	-13.2	-13.5	-10.5	-13.7	-1.3	-13.4	-10.5	-13.6	-13.8	-12.5	-13.6	-13.7	-13.1	-5.4	-13.5	-12.9
Knee pain experienced in last month	28.9	44.9	61.8	7.9	7.5	6.9	3.9	7.8	-1.1	7.5	3.0	7.7	7.8	7.5	7.7	7.0	7.4	3.1	7.5	7.1
Tanning	28.5	348.2	778.4	-18.7	-18.3	-15.7	4.1	-18.4	27.5	-16.5	-4.8	-21.8	-18.0	-27.9	-17.7	-26.2	-17.3	-2.3	-16.3	-20.8
Lung FVC	23.5	119.7	156.2	12.4	11.6	11.5	8.7	12.2	0.8	11.8	7.1	12.5	12.3	12.0	11.7	12.0	12.1	6.4	12.2	11.4
Peak expiratory flow (PEF)	21.5	50.0	67.8	-7.7	-7.2	-7.1	-7.4	-7.9	-3.6	-7.6	-5.5	-7.8	-7.7	-6.0	-7.4	-8.2	-7.6	-3.3	-8.0	-7.7
Hip circumference	18.8	81.1	102.0	-10.1	-9.7	-10.1	-7.5	-9.9	-0.1	-9.8	-8.3	-9.7	-10.1	-9.3	-10.1	-9.8	-9.3	-4.3	-9.7	-9.1
Impedance of leg (left)	14.6	71.0	91.7	9.5	9.2	9.2	5.4	9.5	-1.3	9.3	5.8	9.5	9.6	9.2	9.5	9.1	9.2	3.9	9.3	9.0
Impedance of leg (right)	14.1	68.5	89.6	9.5	9.2	9.2	4.9	9.4	-1.7	9.2	5.2	9.2	9.4	9.0	9.3	9.0	8.9	3.7	9.1	8.9
Hair Pigment	13.1	372.5	934.7	18.7	17.9	16.9	-5.5	18.4	-30.6	16.2	6.7	21.9	18.2	29.7	17.9	27.6	17.7	4.0	15.6	20.5
Waist Hip Ratio (WHR)	11.0	49.5	67.0	7.9	7.4	6.2	6.0	7.8	0.4	7.6	7.5	8.2	7.9	7.1	7.7	7.8	7.5	2.7	7.8	7.3
Relative age voice broke	10.0	15.3	26.8	4.3	4.5	4.4	2.4	4.1	-1.2	4.2	2.9	4.2	4.3	5.2	4.5	4.0	3.6	1.8	4.1	4.3
Trunk fat mass	8.5	36.3	45.6	-6.7	-6.4	-6.8	-5.6	-6.4	-1.1	-6.5	-6.4	-6.3	-6.6	-5.8	-6.6	-6.6	-6.1	-2.9	-6.4	-6.0
Leg fat percentage (right)	7.6	27.6	43.3	6.2	5.8	4.6	3.3	6.4	0.3	5.9	0.2	6.6	6.2	4.8	5.8	5.4	6.3	0.8	6.3	6.4
Qualifications: A levels/AS levels or equivalent	7.2	15.9	20.6	-4.2	-4.0	-3.9	-4.4	-4.3	-1.3	-4.2	-4.5	-4.2	-4.3	-3.9	-4.2	-4.1	-4.0	-2.3	-4.3	-4.2
Medication: Lansoprazole	7.2	8.2	13.9	3.1	3.0	2.9	1.3	3.4	-1.0	2.9	1.4	3.5	3.2	3.7	3.1	2.9	3.2	1.6	3.1	3.4
Leg fat percentage (left)	7.1	25.8	40.9	5.9	5.5	4.3	3.3	6.2	0.5	5.7	0.5	6.4	6.0	4.6	5.6	5.3	6.2	0.8	6.1	6.2
Prostate Cancer	7.0	9.9	14.5	3.5	3.5	2.9	2.5	3.3	0.4	3.6	2.7	3.4	3.5	3.8	3.6	3.1	3.0	2.4	3.5	3.2
Forced vital capacity (FVC), Best measure	6.4	23.4	36.4	-5.5	-5.1	-4.9	-4.2	-5.7	-1.0	-5.2	-3.3	-5.6	-5.4	-3.9	-5.2	-5.3	-5.5	-0.1	-5.5	-6.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.4	13.6	23.6	4.1	4.3	3.8	1.7	4.1	-1.0	4.2	1.0	4.1	4.4	4.9	4.5	3.9	3.6	2.4	3.9	3.6
Impedance of whole body	6.4	32.4	46.5	6.2	6.0	6.8	3.3	6.1	-1.7	6.1	4.9	6.2	6.2	6.6	6.2	6.6	5.8	3.5	5.9	5.9
Qualifications: None of the above	5.9	12.6	18.2	3.8	3.6	3.4	4.3	3.8	2.2	3.9	3.2	3.7	3.8	3.5	3.8	3.7	3.6	2.2	3.9	3.1
Qualifications: O levels/GCSEs or equivalent	5.9	9.3	14.4	-3.4	-3.8	-3.6	-2.7	-3.5	-0.4	-3.6	-1.9	-2.9	-3.6	-3.2	-3.8	-2.6	-2.8	-2.2	-3.3	-2.7
Diabetes (mother)	5.7	7.3	13.7	-2.8	-3.2	-2.8	-2.3	-2.8	-0.5	-3.2	-2.8	-2.8	-2.8	-3.7	-3.2	-2.7	-2.1	-1.6	-2.9	-2.3
Supplements: Zinc	5.6	6.1	12.3	-2.6	-3.1	-2.4	-1.3	-2.6	0.3	-2.9	-1.3	-2.6	-2.6	-3.5	-2.9	-2.6	-1.7	-1.9	-2.6	-2.8
Whole body fat mass	5.5	23.1	30.4	-5.3	-5.1	-5.5	-4.4	-5.0	-0.5	-5.1	-5.5	-4.8	-5.2	-4.8	-5.2	-5.4	-4.8	-2.8	-5.0	-4.7
Forced vital capacity (FVC)	5.3	20.3	29.4	-5.0	-4.9	-4.7	-4.0	-5.3	-1.2	-5.0	-3.3	-5.0	-5.0	-3.8	-5.1	-4.9	-4.8	-0.1	-5.1	-5.4
Qualifications: College or University degree	5.1	16.2	23.1	-4.2	-3.8	-3.4	-4.6	-4.0	-2.7	-4.2	-3.9	-4.5	-4.0	-3.8	-3.7	-4.8	-4.2	-3.6	-4.4	-4.1
Ulcerative Colitis	5.0	7.3	11.7	-2.7	-2.6	-2.8	-2.8	-2.9	-2.0	-2.8	-2.4	-3.3	-2.6	-2.3	-2.5	-3.2	-2.6	-0.5	-3.1	-3.4
Systolic Blood Pressure	5.0	24.9	39.7	-5.5	-5.8	-5.2	-3.2	-5.7	0.2	-5.7	-2.5	-5.5	-5.7	-6.3	-5.8	-4.7	-4.8	-3.1	-5.5	-5.4
Hair/balding pattern: Pattern 3	5.0	7.5	11.2	-3.1	-3.1	-1.9	-2.7	-2.8	-0.9	-3.2	-2.8	-3.3	-2.9	-3.0	-3.0	-3.1	-2.8	-0.5	-3.2	-2.0
Average weekly red wine intake	5.0	7.4	13.4	-2.6	-2.5	-2.0	-3.7	-2.8	-2.3	-2.7	-3.4	-2.6	-2.8	-2.1	-2.6	-2.7	-2.5	-2.8	-2.8	-2.9
Commuting to job workplace: Cycle	5.0	6.0	10.6	-2.7	-2.3	-2.6	-1.3	-2.8	-0.0	-2.5	-0.5	-2.8	-2.9	-2.6	-2.5	-2.6	-3.2	-1.9	-2.6	-3.2
Relative age of first facial hair	4.8	9.8	16.2	3.2	3.3	3.4	3.0	3.1	-0.5	3.2	3.7	3.5	3.2	4.0	3.4	3.3	2.5	1.5	3.2	3.2
Forced expiratory volume in 1-second (FEV1), Best measure	4.7	14.9	25.0	-4.3	-3.6	-4.1	-3.7	-4.5	-1.2	-3.8	-3.0	-4.6	-4.2	-2.6	-3.8	-4.5	-4.7	0.3	-4.4	-5.0
Mouth/teeth dental problems: Mouth ulcers	4.6	7.3	9.8	3.0	2.9	2.4	2.3	3.0	1.1	3.1	1.7	3.0	3.0	2.5	2.9	3.1	3.0	1.8	3.1	3.0
Arm fat mass (right)	4.4	17.9	29.4	-4.5	-4.5	-5.0	-3.7	-4.3	-0.2	-4.5	-5.4	-4.1	-4.5	-4.6	-4.7	-4.6	-3.9	-2.7	-4.3	-4.1
Arm fat mass (left)	4.4	17.9	27.0	-4.6	-4.4	-5.1	-3.7	-4.3	-0.2	-4.5	-5.2	-4.1	-4.5	-4.4	-4.6	-4.7	-4.1	-2.4	-4.3	-4.1
Forced expiratory volume in 1-second (FEV1)	4.3	14.6	20.8	-4.1	-3.7	-4.4	-3.8	-4.4	-1.5	-3.9	-3.4	-4.2	-4.1	-2.8	-4.0	-4.3	-4.3	0.1	-4.3	-4.6
Chronic bronchitis/emphysema (mother)	4.3	5.1	7.8	2.5	2.8	2.0	2.0	2.4	1.0	2.8	1.7	2.4	2.4	2.6	2.7	2.4	1.9	1.5	2.7	1.7
Hair/balding pattern: Pattern 2	4.2	5.4	10.3	2.7	2.7	1.9	0.7	2.6	-1.0	2.5	-0.4	2.8	2.7	3.2	2.7	2.5	2.5	0.0	2.7	2.3
Lung cancer (father)	4.2	4.9	7.0	-2.5	-2.6	-1.0	-2.4	-2.5	-2.1	-2.6	-1.5	-2.3	-2.4	-1.4	-2.5	-2.5	-2.2	-1.0	-2.6	-2.4
Birth weight	4.1	8.9	13.4	-3.5	-3.1	-2.3	-2.8	-3.5	-1.1	-3.4	-1.3	-3.6	-3.5	-1.9	-3.3	-3.5	-3.7	0.9	-3.5	-3.3
Osteoarthritis (self-reported)	4.1	5.3	8.1	2.8	2.8	2.0	0.7	2.6	-0.7	2.7	0.6	2.8	2.7	2.8	2.7	2.1	2.5	0.5	2.8	2.4
LDL Cholesterol	4.0	6.3	13.8	2.7	3.1	3.7	2.1	2.8	0.8	2.9	1.4	2.4	2.8	2.3	2.9	1.8	2.3	2.0	2.8	2.3
Maternal smoking around birth	3.9	5.7	8.6	2.6	2.8	1.2	2.4	2.5	0.5	2.7	2.4	2.4	2.4	2.9	2.6	2.4	1.9	2.9	2.5	2.0
Pulse rate	3.9	6.6	11.2	2.7	2.2	2.4	3.0	2.5	1.6	2.7	3.4	2.5	2.6	2.1	2.5	2.8	2.7	3.3	2.6	1.4
Townsend deprivation index at recruitment	3.6	5.1	8.8	2.2	2.3	1.5	2.5	2.2	0.5	2.4	2.9	2.6	2.2	3.0	2.2	2.4	1.8	1.7	2.5	2.3
Diabetes (father)	3.5	4.4	9.0	-2.2	-2.1	-2.7	-0.6	-2.3	1.5	-2.1	-0.4	-2.2	-2.4	-3.0	-2.4	-2.5	-2.1	-1.5	-1.9	-1.9
Medication: Gliclazide	3.4	3.8	7.1	-1.9	-1.8	-2.3	-1.8	-1.8	-0.5	-1.9	-2.1	-1.9	-2.0	-2.7	-2.2	-2.0	-1.8	-1.8	-1.9	-2.2
Systolic blood pressure, automated reading	3.2	9.2	11.7	-3.0	-3.2	-2.6	-3.2	-3.1	-1.4	-3.4	-3.3	-3.4	-3.0	-3.4	-3.1	-3.4	-2.5	-2.5	-3.4	-3.1
Past tobacco smoking	3.2	5.8	11.4	-2.2	-2.5	-2.0	-3.0	-2.0	-1.5	-2.6	-3.4	-2.7	-2.2	-2.9	-2.4	-2.8	-1.7	-1.0	-2.7	-2.2
Average weekly beer plus cider intake	3.2	4.6	6.8	2.3	2.3	2.3	1.8	2.3	0.0	2.3	0.9	2.3	2.5	2.6	2.3	2.0	2.2	2.0	2.5	2.3
Alcohol intake versus 10 years previously	3.0	4.4	8.8	-2.3	-2.5	-3.0	-1.0	-2.4	-0.1	-2.3	-0.3	-2.1	-2.4	-2.2	-2.4	-1.9	-2.0	-1.8	-2.2	-2.6
Smoking status: Previous	3.0	4.5	7.4	1.9	2.3	2.0	2.6	1.7	1.5	2.4	2.7	2.2	2.0	2.4	2.2	2.5	1.5	1.1	2.4	2.0
Bipolar Disorder (2011)	2.9	2.9	6.1	-1.8	-2.0	-0.5	-1.5	-1.5	-0.2	-1.9	-1.1	-1.9	-1.7	-2.3	-1.6	-2.5	-1.5	-1.8	-1.9	-1.6
Lung FEV1/FVC ratio	2.9	14.7	26.7	-3.9	-2.8	-4.0	-5.0	-3.8	-3.3	-3.3	-3.9	-4.8	-3.7	-2.1	-3.0	-5.2	-4.8	0.5	-4.2	-4.4
Chronotype (morning person)	2.9	6.7	9.9	-3.0	-3.1	-2.3	-2.6	-2.9	-1.8	-3.0	-0.9	-2.9	-2.7	-2.2	-2.7	-2.7	-2.5	-0.8	-3.2	-3.0
Multivitamins +/- minerals	2.9	3.7	6.9	-2.0	-2.1	-1.5	-2.3	-1.9	-1.3	-2.0	-1.9	-2.3	-1.8	-1.8	-1.8	-1.9	-1.6	-0.9	-2.1	-2.6
Number of full sisters	2.9	3.5	6.4	2.3	2.0	1.0	1.2	2.3	-0.2	2.0	0.3	2.4	2.1	1.5	1.9	2.1	2.4	0.5	2.3	2.5
Myopia	2.9	4.2	7.5	-2.4	-2.1	-2.7	-1.5	-2.3	-0.5	-2.2	-0.6	-2.3	-2.3	-1.6	-2.1	-2.2	-2.4	-2.3	-2.1	-1.7
Sensitivity / hurt feelings	2.8	4.8	11.7	2.5	2.4	2.4	0.7	2.3	-1.0	2.4	0.1	2.5	2.4	3.4	2.4	2.7	2.4	1.2	2.4	1.8
High blood pressure (mother)	2.8	3.9	7.0	-2.2	-2.0	-2.0	-1.2	-2.2	0.4	-2.1	-1.5	-2.2	-2.2	-2.1	-2.2	-2.6	-2.1	-1.7	-2.1	-1.5
Number of operations (self-reported)	2.8	4.1	7.2	2.1	1.7	1.5	1.1	2.2	0.3	2.1	1.8	2.4	2.1	2.2	1.8	2.7	2.5	2.1	2.0	2.7
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	9.4	-1.8	-1.6	-1.3	-1.6	-2.0	0.0	-1.5	-0.8	-3.1	-1.7	-1.4	-1.3	-2.1	-2.1	2.4	-2.2	-3.0
Coronary Artery Disease (CAD)	2.7	3.2	6.1	-1.8	-1.2	-2.5	-2.5	-1.8	-0.5	-1.4	-2.3	-1.7	-1.9	-1.6	-1.7	-1.7	-2.1	-1.4	-1.6	-1.7
Qualifications: CSEs or equivalent	2.7	3.5	7.5	2.0	1.7	2.3	2.7	1.9	1.6	1.8	2.0	1.9	1.8	1.4	1.6	2.0	1.9	1.3	2.1	1.3
Pulse wave reflection index	2.7	3.4	6.4	-1.9	-1.6	-1.7	-2.1	-1.8	-1.2	-2.0	-2.0	-2.0	-1.9	-1.5	-1.8	-2.5	-2.0	-1.8	-1.8	-0.8
Commuting to job workplace: Walk	2.6	2.8	4.4	-1.9	-1.7	-2.0	-1.3	-2.0	-0.6	-1.8	-0.1	-2.1	-1.9	-1.5	-1.7	-1.7	-2.0	-1.0	-1.9	-1.8
Waist circumference	2.5	9.2	20.1	-3.2	-3.3	-4.5	-2.4	-3.1	0.0	-3.2	-3.2	-2.6	-3.2	-3.3	-3.4	-3.3	-2.7	-2.4	-2.9	-2.6
Ulcerative Colitis (UC)	2.4	4.4	11.0	-1.5	-1.5	-1.5	-3.1	-1.8	-3.3	-1.8	-3.1	-2.5	-1.4	-1.0	-1.3	-2.2	-1.6	-1.1	-2.1	-2.8
Blood clot in the leg (DVT)	2.4	3.0	8.0	-1.7	-1.5	-1.2	-1.4	-1.8	0.2	-1.4	-0.8	-2.8	-1.5	-1.4	-1.2	-1.8	-1.8	2.3	-2.1	-2.8
Age at last live birth	2.4	3.5	4.7	-2.1	-1.9	-1.7	-1.7	-2.1	-0.6	-2.0	-0.9	-1.9	-2.1	-1.8	-1.9	-2.1	-2.2	-2.0	-1.9	-2.2
Mouth/teeth dental problems: Bleeding gums	2.3	3.0	6.9	1.8	1.4	1.3	1.7	1.8	1.0	1.6	0.8	2.5	1.7	1.2	1.3	2.6	2.1	0.1	2.0	2.5
Heel T-Score	2.2	17.2	70.1	3.7	3.4	2.2	-5.5	4.2	-8.4	2.6	-7.4	2.7	3.9	2.4	3.5	1.6	4.3	-1.9	2.6	3.3
Alcohol usually taken with meals	2.2	3.5	6.4	-1.9	-1.9	-2.5	-1.1	-2.1	1.1	-1.8	-0.9	-1.6	-2.1	-2.5	-1.9	-1.6	-1.8	-2.5	-1.8	-1.9
Fluid intelligence score	2.2	4.6	10.8	-2.2	-1.9	-3.3	-3.1	-2.0	-1.5	-2.1	-2.5	-1.9	-2.1	-1.4	-1.9	-2.3	-2.3	-1.6	-2.1	-1.1
Average weekly champagne plus white wine intake	2.2	3.1	5.0	-2.1	-1.7	-1.9	-1.2	-1.9	0.0	-1.9	-0.9	-2.1	-2.0	-1.6	-1.9	-2.2	-2.2	-1.3	-1.9	-1.2
Eye problems/disorders: Glaucoma	2.2	2.6	4.0	1.9	2.0	1.6	1.9	1.6	1.7	2.0	1.4	1.6	1.6	1.0	1.8	1.2	1.4	0.6	1.9	1.3
Alzheimer’s Disease (in father)	2.1	2.2	8.7	1.3	1.7	1.1	1.9	1.6	1.6	1.6	0.8	1.0	1.2	1.0	1.4	1.2	0.9	2.9	1.5	1.4
HDL Cholesterol	2.1	3.5	9.0	1.6	1.6	2.7	2.8	1.2	0.9	2.0	3.0	1.8	1.7	1.8	1.7	2.0	1.5	0.8	1.9	1.4
Nervous feelings	2.1	3.9	12.2	2.1	2.4	0.9	-1.0	1.9	-2.9	2.1	-0.6	1.9	2.0	3.5	2.3	2.1	1.6	0.3	1.8	1.4
Impedance of arm (left)	2.1	9.5	17.6	3.1	3.1	4.2	1.6	3.0	-1.4	3.0	3.6	3.1	3.0	3.9	3.1	3.8	2.7	3.0	2.8	2.9
Ever taken oral contraceptive pill	2.1	2.4	3.4	1.8	1.8	1.8	0.5	1.7	-1.0	1.6	-0.4	1.8	1.7	1.8	1.6	1.7	1.7	-0.6	1.8	1.8
Had menopause	2.0	2.5	5.0	-1.6	-1.7	-1.5	-2.2	-1.7	-2.0	-1.7	-1.3	-1.8	-1.4	-0.5	-1.3	-2.1	-1.2	-0.1	-1.8	-1.3
Basal cell carcinoma (self-reported)	2.0	2.4	19.2	-0.2	-0.5	-0.1	-3.2	-0.2	-4.4	-0.8	-2.2	0.1	-0.3	0.3	-0.6	0.2	0.2	-2.1	-0.7	0.5
Major Depression (MDD)	1.9	2.3	5.5	1.8	1.4	1.0	0.2	1.6	-0.6	1.6	-1.0	1.8	1.8	1.6	1.5	1.8	2.3	0.6	1.7	1.8
Diverticular disease/diverticulitis (self-reported)	1.9	2.2	3.9	1.8	1.7	1.2	0.1	1.9	-1.0	1.6	-0.2	1.7	1.6	2.0	1.5	1.5	1.8	-0.1	1.7	1.7
Mouth/teeth dental problems	1.9	2.8	6.6	-1.3	-1.0	-1.7	-2.4	-1.4	-2.6	-1.5	-1.8	-1.9	-1.5	-0.9	-1.2	-2.1	-1.6	-1.7	-1.7	-1.6
Diabetes (self-reported)	1.9	2.9	6.6	-1.8	-1.7	-2.6	-1.2	-1.7	0.3	-1.8	-1.0	-1.7	-1.8	-2.0	-1.9	-2.3	-1.7	-1.3	-1.6	-1.4
Tinnitus: Yes, now most or all of the time	1.9	2.2	6.4	-1.2	-1.2	-1.5	-2.3	-1.2	-2.5	-1.6	-1.2	-1.2	-1.2	-0.7	-1.2	-1.7	-1.2	-1.8	-1.5	-0.8
Cholesterol lowering medication	1.9	2.7	5.5	1.9	1.6	2.2	0.9	1.9	-0.1	1.7	-0.7	1.8	2.2	1.2	1.9	1.6	2.3	0.5	1.8	1.9
Age when periods started (menarche)	1.8	4.4	12.4	1.9	2.5	2.6	1.0	1.8	-1.9	2.3	2.7	1.3	2.2	3.5	2.9	1.6	1.0	1.5	1.8	1.1
Impedance of arm (right)	1.8	8.6	19.3	2.9	2.7	4.4	1.3	2.9	-2.0	2.7	2.9	2.9	2.9	3.6	2.8	3.8	2.9	2.8	2.5	2.6
Pulse wave Arterial Stiffness index	1.8	2.1	3.9	-1.6	-1.5	-1.0	-2.0	-1.5	-1.2	-1.6	-2.0	-1.6	-1.4	-1.1	-1.4	-1.7	-1.4	-0.8	-1.6	-1.1
High cholesterol (Self-reported)	1.8	3.3	7.1	2.1	1.5	2.7	1.0	2.1	-0.1	1.6	0.5	2.2	2.2	0.9	1.8	1.8	2.5	0.2	2.0	2.4
Pack years of smoking	1.8	2.6	6.0	-1.5	-1.7	-1.8	-2.5	-1.4	-2.0	-1.7	-1.2	-1.6	-1.6	-0.9	-1.5	-2.0	-1.4	0.4	-1.8	-1.7
Alzheimer’s Disease (including proxy)	1.7	2.4	4.7	1.7	1.5	1.6	1.5	1.8	0.9	1.5	1.1	1.5	1.4	1.1	1.4	1.8	1.8	2.2	1.6	1.6
Lupus	1.7	2.5	5.3	-1.6	-1.1	-0.9	-1.7	-1.7	-1.2	-1.4	-0.9	-2.3	-1.7	-0.8	-1.2	-2.3	-2.3	-0.6	-1.8	-2.0
Vitamin and mineral supplements	1.7	2.3	6.1	1.2	1.4	1.1	2.5	1.3	2.1	1.4	1.7	1.8	1.3	0.7	1.2	1.6	1.1	0.2	1.5	2.2
Neck or shoulder pain in last month	1.7	2.4	10.8	-1.1	-1.2	-1.0	-2.9	-0.9	-3.3	-1.3	-2.7	-1.0	-1.0	-0.7	-1.2	-1.2	-0.6	-0.8	-1.2	-0.6
Family relationship satisfaction	1.7	2.1	3.7	-1.6	-1.5	-1.9	-1.0	-1.7	0.1	-1.5	-1.1	-1.1	-1.6	-1.8	-1.7	-1.1	-1.4	-1.9	-1.4	-1.3
Length of working week for main job	1.6	1.8	4.3	-1.5	-1.3	-2.1	-0.2	-1.3	1.3	-1.3	-0.7	-1.6	-1.5	-1.6	-1.4	-1.3	-1.5	-0.5	-1.3	-1.0
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	7.3	-2.0	-1.9	-2.4	-0.9	-2.0	-0.1	-2.0	-1.0	-1.7	-2.0	-1.6	-2.0	-2.7	-1.9	-1.4	-1.7	-1.5
Mouth/teeth dental problems: Loose teeth	1.6	1.9	4.3	-1.6	-1.6	-0.7	-0.8	-1.6	0.3	-1.6	-1.3	-1.5	-1.5	-1.3	-1.4	-2.1	-1.6	-1.1	-1.5	-1.1
Leg fat mass (left)	1.6	6.1	19.0	-2.4	-2.3	-3.3	-2.5	-2.2	-0.1	-2.3	-4.4	-2.0	-2.4	-2.6	-2.5	-2.7	-2.0	-2.2	-2.1	-1.8
Hearing difficulty/problems: Yes	1.5	2.2	7.1	1.3	1.3	1.6	-0.8	1.4	-2.7	1.3	0.4	1.1	1.4	2.5	1.6	1.4	1.1	0.8	1.1	1.7
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	3.0	-1.5	-1.4	-1.5	-1.7	-1.7	-1.4	-1.4	-0.8	-1.2	-1.5	-0.6	-1.5	-1.4	-1.4	-0.7	-1.3	-1.3
Breastfed as a baby	1.5	1.9	8.0	0.9	0.7	1.0	1.4	1.0	0.6	1.0	2.8	1.5	1.1	1.5	1.1	2.0	1.2	1.6	0.9	1.2
Medication for cholesterol	1.5	2.3	4.3	-1.8	-1.5	-1.2	-0.6	-1.7	0.5	-1.6	-0.1	-1.9	-1.9	-1.6	-1.8	-1.8	-2.1	0.3	-1.7	-1.7
Irritability	1.5	2.5	9.3	1.2	1.6	-0.0	-1.2	1.0	-3.1	1.3	0.0	1.7	1.1	2.5	1.4	1.6	0.6	-2.6	1.2	1.2
Irritable Bowel Disease (IBD)	1.4	3.4	7.6	-1.8	-1.8	-1.5	-1.8	-2.0	-1.4	-1.9	-1.6	-2.3	-1.7	-1.6	-1.7	-2.0	-1.8	-1.0	-2.1	-2.8
Reaction Time	1.4	2.7	7.0	1.4	0.9	1.8	2.5	1.3	2.6	1.3	1.7	1.6	1.2	-0.3	0.9	2.4	1.7	1.6	1.5	1.6
Leg fat mass (right)	1.4	5.3	18.8	-2.1	-2.1	-3.0	-2.3	-1.9	-0.1	-2.1	-4.3	-1.7	-2.1	-2.5	-2.3	-2.6	-1.8	-2.2	-1.9	-1.6
Overall health rating	1.4	3.1	6.7	2.1	1.7	0.7	0.1	2.1	-1.1	1.8	-0.6	2.3	2.0	1.8	1.8	2.1	2.6	-0.2	2.0	1.9
Pain type(s) experienced in last month: Hip pain	1.4	1.8	9.7	-0.3	-0.8	-0.8	-2.3	-0.3	-2.7	-0.9	-3.1	-0.0	-0.5	-0.7	-0.9	-0.8	0.2	-2.0	-0.4	0.2
Risk taking	1.4	2.1	8.2	-1.1	-1.1	-1.1	-1.5	-1.0	-0.2	-1.2	-2.9	-1.4	-1.1	-1.5	-1.1	-1.7	-1.1	-1.8	-1.2	-2.0
Schizophrenia vs Biploar Disorder	1.3	1.7	4.4	1.3	1.7	1.6	0.2	1.2	-1.4	1.6	0.2	1.0	1.4	2.1	1.7	0.8	0.9	1.6	1.3	0.5
HbA1C	1.3	1.4	4.0	1.1	0.7	0.8	1.9	1.0	1.9	0.9	2.0	1.0	1.0	-0.1	0.7	1.6	1.1	0.6	0.9	1.1
Type 2 Diabetes (T2D) (2012)	1.3	1.4	4.0	-1.1	-0.7	-1.7	-2.0	-1.0	-1.4	-0.9	-1.4	-1.4	-1.0	-0.5	-0.9	-1.5	-1.2	-0.8	-1.0	-1.0
Medication: Metformin	1.3	1.8	4.3	-1.4	-1.1	-2.1	-0.3	-1.4	1.2	-1.2	0.1	-1.3	-1.4	-1.8	-1.3	-1.7	-1.4	-1.4	-1.1	-1.3
Mouth/teeth dental problems: Dentures	1.3	2.2	4.0	-1.8	-1.8	-0.6	0.4	-1.6	1.9	-1.4	0.9	-1.7	-1.5	-1.6	-1.5	-1.2	-1.6	2.0	-1.5	-1.5
Exposure to tobacco smoke at home	1.3	1.5	2.4	1.3	1.1	0.3	1.3	1.3	-0.0	1.1	1.5	1.4	1.3	1.4	1.2	1.2	1.5	1.0	1.3	1.6
Pulse rate, automated reading	1.3	4.3	22.8	1.5	0.9	1.2	3.2	1.3	2.7	1.5	4.8	1.6	1.4	1.1	1.2	2.0	1.7	2.6	1.5	1.2
Had major operations	1.3	1.5	6.4	0.9	0.9	0.6	1.4	0.9	1.4	1.2	2.5	1.2	0.8	0.9	0.9	1.4	0.8	1.4	1.0	1.2
Bipolar Disorder or Schizophrenia	1.2	2.9	12.5	-1.2	-1.5	-1.6	-2.5	-1.2	-0.8	-1.4	-3.5	-1.5	-1.3	-2.0	-1.5	-1.5	-0.7	-1.6	-1.5	-1.4
Intelligence (Savage-Jansen 2018)	1.2	3.6	12.0	-1.8	-1.3	-3.5	-2.6	-1.8	-1.1	-1.7	-2.1	-2.0	-1.7	-1.4	-1.5	-2.1	-2.1	-0.3	-1.8	-1.1
Verbal and Numeric Reasoning (VNR)	1.2	2.8	8.5	-1.5	-1.1	-2.4	-2.9	-1.4	-1.9	-1.5	-2.4	-1.6	-1.3	-0.8	-1.1	-2.0	-1.7	-0.6	-1.5	-0.9
Age at First Birth	1.2	1.8	7.5	-0.8	-0.6	0.1	-2.6	-0.8	-2.7	-0.8	-2.5	-1.2	-0.7	0.0	-0.7	-0.9	-0.7	-0.9	-1.1	-1.3
Medication: Co-codamol	1.2	1.4	3.4	1.5	1.1	0.2	0.5	1.4	-0.2	1.2	1.0	1.8	1.2	1.2	1.0	1.1	1.6	-0.2	1.5	1.3
Medication: Atenolol	1.2	1.5	4.7	-1.2	-1.6	-1.3	-0.8	-1.2	-0.2	-1.4	-0.7	-0.7	-1.3	-1.4	-1.5	-0.5	-0.8	-2.2	-1.2	-1.4
Medication: Levothyroxine sodium	1.2	2.1	4.8	-1.7	-1.6	-1.7	-1.1	-1.6	-0.3	-1.7	-1.1	-1.5	-1.6	-1.1	-1.6	-2.2	-1.6	-0.4	-1.4	-1.0
Hair/balding pattern: Pattern 4	1.2	2.8	16.1	0.3	0.1	0.5	-3.7	0.2	-4.0	-0.4	-3.7	-0.7	0.1	-0.6	-0.1	-0.9	0.4	-1.1	-0.4	-0.6
Illnesses of siblings: Diabetes	1.2	1.4	6.6	-0.3	-0.8	-1.5	-2.0	-0.2	-2.1	-1.0	-2.6	-0.2	-0.4	-0.7	-0.9	-0.6	0.5	-1.8	-0.6	-0.0
Alcohol drinker status: Previous	1.2	1.4	3.0	-1.4	-1.7	-0.5	-0.9	-1.4	-0.7	-1.5	0.4	-1.3	-1.3	-1.0	-1.3	-1.2	-1.0	-1.2	-1.3	-0.9
Bipolar Disorder (2018)	1.1	1.8	5.0	-0.9	-1.0	-1.9	-1.2	-1.1	1.0	-1.0	-2.2	-1.4	-1.1	-2.2	-1.2	-1.5	-0.7	-1.4	-1.1	-0.9
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	5.1	1.1	1.0	0.3	-0.8	1.0	-1.9	1.0	0.3	1.3	0.9	2.2	0.9	1.5	1.0	1.7	1.0	0.8
Pack years adult smoking proportion	1.1	1.6	3.7	-1.1	-1.2	-1.6	-1.9	-1.0	-1.6	-1.2	-1.1	-1.3	-1.2	-0.6	-1.1	-1.6	-1.1	0.8	-1.3	-1.6
Eye problems/disorders: None of the above	1.1	1.3	2.7	-1.5	-1.3	-0.6	-0.3	-1.4	0.2	-1.2	0.3	-1.4	-1.3	-0.8	-1.2	-1.1	-1.6	-0.6	-1.4	-1.4
Supplements: Vitamin C	1.1	1.3	2.6	-1.1	-1.5	-1.0	-0.9	-1.3	0.0	-1.4	-0.7	-1.4	-1.2	-1.5	-1.4	-1.2	-0.8	-0.2	-1.2	-1.6
Mineral and other dietary supplements	1.1	1.5	3.2	-1.4	-0.8	-1.6	0.6	-1.4	1.6	-1.0	0.6	-1.3	-1.4	-1.3	-1.2	-1.4	-1.8	0.5	-1.0	-1.0
Pain experienced in last month	1.1	1.8	4.0	-1.5	-1.4	-1.2	0.2	-1.4	1.7	-1.3	-0.6	-1.6	-1.3	-1.8	-1.3	-1.0	-1.3	-1.2	-1.3	-2.0
Depression (Nagel 2018)	1.0	1.5	3.6	-1.2	-1.2	-1.7	-1.7	-1.0	-1.5	-1.1	-1.9	-0.7	-1.1	-0.4	-1.1	-0.9	-0.9	-1.8	-0.8	-0.8
Average weekly fortified wine intake	1.0	1.1	2.8	-1.0	-0.8	0.1	-1.1	-0.9	-1.7	-1.0	-1.2	-1.3	-0.8	-0.8	-0.8	-1.4	-1.1	-0.9	-1.2	-1.1
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	6.1	0.5	0.1	0.8	1.9	0.4	2.5	0.7	1.6	0.6	0.7	0.1	0.5	1.1	1.1	1.4	0.7	0.3
Supplements: Glucosamine	1.0	1.3	6.1	0.7	0.6	1.2	-2.1	0.8	-2.3	0.4	-2.5	0.5	0.8	1.3	0.7	-0.0	0.7	-0.1	0.3	0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.4	14.6	-0.5	-0.6	-0.8	-2.9	-0.1	-2.4	-0.8	-3.8	-0.8	-0.4	-1.4	-0.5	-1.3	0.0	-2.2	-0.7	0.0
Allergy	1.0	2.3	6.3	1.2	1.3	0.8	2.2	1.1	2.2	1.4	2.5	1.7	1.0	1.1	1.0	1.6	1.0	1.4	1.4	1.7
Emphysema/chronic bronchitis	1.0	1.1	2.2	1.1	1.1	1.2	0.7	1.2	-0.5	1.0	0.5	1.2	1.2	1.5	1.0	1.5	1.2	0.6	1.2	0.6
Medication: Aspirin	1.0	1.3	2.8	1.2	0.9	1.1	0.1	1.6	-0.6	0.9	-1.2	1.7	1.1	0.1	0.9	1.1	1.6	-1.5	1.2	1.4
Arm fat percentage (left)	1.0	4.0	8.0	2.3	2.1	1.2	1.2	2.6	0.5	2.1	-1.0	2.8	2.3	1.6	2.0	2.1	2.5	0.2	2.4	2.5
Neuroticism (Nagel 2018)	0.9	2.2	7.6	1.2	1.4	0.2	-1.1	1.0	-2.8	1.3	-1.0	1.3	1.2	2.8	1.4	1.5	1.0	-1.1	1.2	1.2
Crohns Disease (2012)	0.9	1.4	2.7	-1.3	-1.3	-1.2	-0.4	-1.3	-0.3	-1.3	0.1	-1.2	-1.3	-1.5	-1.3	-0.9	-1.4	-1.3	-1.3	-1.6
Mean Putamen Volume	0.9	1.1	2.4	-1.0	-1.2	-0.5	-0.1	-1.0	1.5	-1.1	-0.6	-1.3	-0.9	-1.5	-1.1	-1.5	-0.7	0.5	-1.0	-0.7
Hypothyroidism (self reported)	0.9	2.1	5.3	-1.6	-1.4	-1.9	-0.3	-1.6	0.4	-1.5	-1.0	-1.6	-1.6	-1.5	-1.6	-2.3	-1.6	-0.2	-1.4	-1.4
Respiratory disease	0.9	1.9	3.8	-1.2	-1.4	-1.9	-1.8	-1.1	-1.7	-1.4	-1.8	-1.6	-1.1	-0.6	-1.1	-1.7	-1.0	-0.8	-1.3	-1.4
Fed-up feelings	0.9	1.7	3.8	1.3	1.2	-0.1	1.2	1.3	1.2	1.5	-0.1	1.7	1.4	1.2	1.3	1.9	1.5	0.3	1.7	1.3
Number of incorrect matches in round	0.9	1.5	4.2	1.1	1.3	2.1	1.3	1.1	1.3	1.2	1.0	0.8	1.1	1.0	1.2	0.9	0.8	1.8	1.1	1.3
Depression (self-reported)	0.9	1.1	5.5	0.3	-0.0	0.3	2.3	0.3	2.3	0.5	1.3	1.2	0.3	0.2	0.1	1.2	0.6	-0.8	0.8	0.7
Medication for pain relief, constipation, heartburn	0.9	1.5	3.9	-1.3	-1.2	-0.7	-0.7	-1.5	-0.4	-1.4	-0.3	-2.0	-1.2	-1.0	-1.2	-1.5	-1.5	0.5	-1.5	-1.8
Medication: Atorvastatin	0.9	1.1	3.0	0.9	0.7	1.2	0.8	1.2	0.6	1.0	-0.2	0.9	1.1	0.9	0.9	1.2	1.1	1.7	1.0	1.3
Alcohol drinker status: Never	0.9	1.1	2.8	0.9	0.6	1.2	1.3	1.0	0.4	0.7	1.5	1.0	1.1	0.6	0.7	1.0	1.2	1.7	0.9	1.1
Worry (Nagel 2018)	0.8	1.7	14.8	0.3	0.3	-0.4	-2.6	0.0	-3.8	0.3	-1.6	0.1	0.3	1.6	0.4	0.6	0.3	-0.9	-0.1	0.2
Rheumatoid Arthritis	0.8	1.1	7.7	-0.6	-0.5	-0.6	1.3	-0.8	1.6	-0.2	2.8	-0.4	-0.6	0.3	-0.5	0.5	-0.8	1.5	-0.4	-0.9
Smoking Status	0.8	2.0	8.7	0.9	1.2	0.7	2.2	0.7	1.6	1.3	3.0	1.3	0.8	1.7	1.1	1.3	0.4	1.4	1.3	1.1
Hearing difficulty/problems with background noise	0.8	1.3	11.9	0.5	0.8	0.4	-2.1	0.5	-3.4	0.5	-0.8	0.2	0.4	1.8	0.8	-0.0	0.3	0.0	0.2	0.3
Illnesses of siblings	0.8	1.1	7.5	-0.5	-0.2	0.9	1.5	-0.5	1.7	0.0	2.7	-0.3	-0.3	0.1	0.0	0.2	-0.8	1.7	-0.2	-0.9
Arm fat percentage (right)	0.8	3.2	6.6	2.0	1.7	1.2	0.8	2.3	0.1	1.8	-1.6	2.6	2.1	1.3	1.7	2.0	2.5	-0.1	2.2	2.2
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	13.5	-0.3	-0.2	-1.5	-2.0	-0.3	-0.9	-0.3	-3.7	-0.4	-0.3	-0.2	-0.5	-0.3	0.1	-0.5	-0.2	-0.1
Asthma	0.8	1.6	3.2	-1.2	-1.6	-1.8	-1.3	-1.2	-1.1	-1.5	-1.3	-1.2	-1.0	-1.1	-1.3	-1.3	-0.6	-1.5	-1.2	-0.5
Comparative body size at age 10	0.8	2.2	4.9	1.6	1.7	0.6	1.3	1.8	2.2	1.7	-1.2	1.6	1.5	0.7	1.4	1.1	1.4	1.7	1.7	1.5
Age at first live birth	0.8	1.5	3.9	-1.3	-1.1	-0.5	-1.6	-1.1	-0.8	-1.2	-1.5	-1.1	-1.2	-0.8	-1.1	-1.1	-1.3	-2.0	-1.2	-1.0
Mean time to correctly identify matches	0.8	1.5	4.0	1.0	0.6	2.0	1.7	1.0	1.7	0.9	1.3	1.2	1.0	-0.2	0.6	1.7	1.4	1.2	1.1	1.3
Chest pain or discomfort	0.8	1.1	3.3	-0.8	-1.0	-1.6	-1.8	-0.8	-1.7	-0.8	-1.8	-0.7	-0.6	-0.6	-0.6	-1.1	-0.2	-0.9	-0.7	-0.1
Diabetes diagnosed by doctor	0.8	1.3	4.2	-1.2	-1.0	-2.0	-0.7	-1.0	0.3	-1.1	-0.5	-0.9	-1.2	-1.4	-1.2	-1.8	-1.1	-1.1	-0.9	-0.8
Supplements: Fish oil (including cod liver oil)	0.8	1.1	2.6	1.2	0.8	1.1	-0.6	1.2	-1.3	0.9	-0.6	1.0	1.2	0.8	0.9	1.5	1.6	0.2	0.9	1.2
Age started oral contraceptive pill	0.8	1.0	5.9	0.4	0.5	1.1	-1.4	0.3	-2.4	0.5	-0.4	-0.1	0.7	1.9	0.9	0.5	0.3	0.9	0.0	-0.4
Schizophrenia (2018)	0.7	1.5	7.8	-0.8	-1.1	-0.6	-2.2	-0.7	-1.8	-1.0	-2.8	-0.9	-0.7	-0.8	-0.9	-0.7	-0.4	-0.8	-1.0	-1.0
Body Mass Index (BMI) (2010)	0.7	0.9	7.3	-0.5	-0.5	-0.8	-1.0	-0.5	0.2	-0.9	-2.7	-0.7	-0.7	-1.2	-1.0	-1.2	-0.4	-0.1	-0.6	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	12.8	0.7	0.6	-0.2	-2.0	0.9	-1.5	0.4	-3.6	0.3	0.7	-0.6	0.5	0.1	1.1	-1.1	0.4	1.3
Chronic bronchitis/emphysema (father)	0.7	0.8	5.1	0.7	0.3	0.7	1.3	0.6	1.2	0.6	0.6	0.7	0.6	0.2	0.5	0.8	1.0	2.2	0.8	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.4	1.0	1.0	-1.0	-0.4	1.1	-0.9	0.9	-0.7	1.5	0.8	1.4	0.6	1.1	1.0	-0.4	1.2	1.6
Neuroticism score	0.7	1.5	4.0	1.2	1.2	-0.6	-0.5	1.0	-1.7	1.3	-0.7	1.4	1.1	2.0	1.2	1.7	1.2	-0.7	1.2	1.0
Father’s age at death	0.7	1.0	2.3	-1.1	-0.7	-0.8	-0.3	-1.1	-0.0	-1.1	0.4	-1.2	-1.2	-0.7	-1.0	-1.4	-1.5	-1.3	-1.1	-0.4
Body fat percentage	0.7	2.8	5.7	1.9	1.7	1.1	0.6	2.1	0.0	1.8	-1.3	2.4	1.9	1.5	1.6	1.6	2.1	-0.0	2.0	2.2
Worry too long after embarrassment	0.7	1.2	5.9	0.8	0.9	0.1	-1.1	0.8	-2.4	0.7	-1.3	1.0	0.7	1.5	0.7	1.2	0.6	-0.9	0.8	0.8
Wheeze or whistling in the chest in last year	0.7	1.3	3.1	-1.3	-1.7	-1.8	-0.5	-1.1	-0.3	-1.4	-0.1	-1.0	-1.1	-1.2	-1.3	-0.9	-0.6	-1.6	-1.1	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.3	0.8	0.7	0.7	0.4	0.8	-0.9	0.8	1.5	1.0	0.9	1.0	0.9	0.8	0.9	-0.6	0.8	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.2	-1.2	-0.8	-1.0	-0.2	-1.2	0.6	-0.8	-0.5	-1.1	-1.1	-1.0	-0.9	-1.0	-1.5	-0.1	-0.9	-0.5
Asthma (self-reported)	0.7	1.4	3.1	-1.2	-1.6	-1.8	-1.1	-1.1	-0.9	-1.5	-1.0	-1.1	-1.0	-1.1	-1.3	-1.3	-0.6	-1.3	-1.2	-0.5
Commuting to job workplace: Public transport	0.7	0.8	1.4	-1.1	-1.0	-0.9	-0.8	-1.0	-0.6	-1.1	0.6	-0.9	-0.8	-0.9	-0.8	-1.1	-1.0	0.1	-1.2	-0.7
Unable to work because of sickness or disability	0.7	1.0	2.9	1.0	0.8	0.6	1.2	1.0	0.8	1.0	0.6	1.3	0.8	1.3	0.7	1.7	0.9	0.5	1.1	0.5
Fasting Glucose	0.6	0.8	1.9	-0.7	-0.7	-0.1	-1.4	-0.8	-1.1	-0.8	-1.1	-1.1	-0.6	-0.7	-0.5	-0.8	-0.7	-1.4	-0.9	-0.5
Schizophrenia (2014)	0.6	1.4	5.0	-1.0	-1.2	-0.9	-1.6	-1.0	-0.8	-1.1	-2.2	-1.2	-0.9	-1.4	-1.1	-1.0	-0.6	-0.6	-1.1	-1.2
Severe depression (siblings)	0.6	0.7	3.4	0.5	0.5	-0.0	-1.7	0.3	-1.8	0.3	-1.9	0.1	0.5	0.3	0.4	-0.4	0.8	-0.8	0.2	0.2
Hayfever, allergic rhinitis or eczema	0.6	1.3	5.2	-0.8	-0.9	0.1	-1.7	-0.7	-1.8	-0.9	-2.3	-1.0	-0.5	-0.9	-0.6	-0.8	-0.5	-1.8	-0.9	-1.2
Stomach or abdominal pain in last month	0.6	0.7	1.5	1.0	1.0	0.2	-0.5	0.8	-1.2	0.9	-0.5	1.0	0.7	1.0	0.9	0.5	0.8	-0.8	0.9	1.1
Noisy workplace	0.6	0.7	2.8	0.7	0.7	0.9	0.6	0.6	0.3	0.6	0.1	0.7	0.7	1.3	0.7	1.0	0.6	1.7	0.7	0.7
Loud music exposure frequency	0.6	0.7	1.9	0.8	0.3	1.1	-0.1	0.8	-1.2	0.6	-0.1	1.1	0.9	0.9	0.6	1.3	1.4	-0.0	0.7	0.2
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.3	-0.9	-1.4	-1.4	-0.0	-0.8	0.8	-1.2	0.0	-0.4	-0.7	-1.2	-1.1	-0.2	-0.0	-1.5	-0.9	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.4	-0.2	-0.6	0.1	-1.7	-0.2	-1.8	-0.6	-1.7	-0.4	-0.1	0.2	-0.4	-0.3	0.5	-0.9	-0.6	-0.0
Medication: Allopurinol	0.6	0.9	1.3	1.0	1.1	1.0	0.3	1.1	-0.2	1.1	-0.9	0.8	1.1	0.9	1.0	0.8	0.9	1.1	0.9	0.9
Illnesses of father: Heart disease	0.6	0.9	6.0	0.6	0.5	0.3	-1.2	0.7	-1.0	0.4	-2.4	0.8	0.6	0.3	0.5	-0.1	0.9	-1.3	0.6	1.1
Qualifications: nursing, teaching	0.6	0.9	2.8	-0.9	-1.1	-0.9	-1.0	-0.9	-0.1	-0.9	-1.1	-0.6	-0.9	-1.3	-1.1	-0.5	-0.4	-1.7	-0.9	-0.7
Back pain experienced in last month	0.6	0.9	4.4	-0.6	-0.1	0.6	-1.3	-0.5	-2.1	-0.3	-0.4	-0.8	-0.5	1.2	-0.2	-1.1	-1.1	1.8	-0.6	-0.7
Depressed Affect (Nagel 2018)	0.5	1.1	3.0	1.1	1.3	0.1	0.3	1.0	-0.4	1.3	-0.3	1.2	1.2	1.7	1.3	1.1	1.1	0.2	1.4	1.1
Breast Cancer	0.5	1.2	6.2	0.6	0.4	1.8	2.0	0.6	2.5	0.6	1.1	0.7	0.7	-0.3	0.5	0.8	0.8	0.8	0.9	0.9
Primary Biliary Cirrhosis	0.5	0.7	3.2	-0.5	-0.8	-0.8	0.7	-0.5	1.8	-0.6	-0.2	-0.7	-0.6	-1.3	-0.8	-0.5	-0.2	1.5	-0.5	-0.6
Neuroticism	0.5	1.2	7.3	0.2	0.3	-1.4	-2.1	0.1	-2.7	0.1	-1.8	0.3	0.0	1.1	0.2	0.5	0.2	-1.3	0.2	0.2
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.3	0.8	0.6	0.4	-0.8	0.8	-1.8	0.5	-0.6	0.6	0.8	0.6	0.8	0.3	0.9	-0.6	0.6	0.4
Serious illness, injury or assault to yourself	0.5	0.6	1.1	0.9	0.6	0.3	0.5	0.8	0.5	0.8	0.2	1.0	0.7	0.6	0.6	1.0	1.0	-0.7	0.9	1.0
Had other major operations	0.5	0.6	1.4	0.8	0.5	0.4	-0.7	0.8	-0.7	0.7	-1.0	0.7	0.7	0.9	0.6	1.0	1.2	0.8	0.7	0.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.6	-0.8	-1.0	-0.3	-0.7	-0.8	-0.6	-0.8	-1.1	-1.1	-0.5	-1.2	-0.7	-0.6	-0.2	-0.1	-0.9	-1.3
Prospective memory result	0.5	0.6	2.3	0.5	0.5	1.4	0.9	0.5	0.4	0.6	0.6	0.4	0.7	1.0	0.7	0.6	0.5	1.5	0.6	-0.1
Tense / ‘highly strung’	0.5	0.8	5.9	0.2	0.2	-0.8	-1.3	0.2	-2.4	0.2	-0.7	0.4	0.1	1.2	0.2	0.7	0.2	-1.3	0.1	0.2
Medication: Paracetamol	0.5	0.8	1.7	0.9	1.0	-0.0	0.7	0.8	0.6	1.1	0.6	1.3	0.8	0.6	0.8	1.1	1.0	-0.3	1.1	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.4	-0.7	-0.9	-1.3	0.5	-0.8	1.5	-0.7	-0.8	-0.2	-0.7	-1.2	-1.0	-0.5	-0.3	-0.4	-0.2	-0.6
Health satisfaction	0.5	0.6	4.1	0.2	0.3	-0.5	-1.4	0.3	-1.9	0.2	-2.0	-0.0	0.3	0.7	0.4	-0.0	0.2	-0.1	0.2	0.2
Heart disease (mother)	0.5	0.6	5.5	0.6	0.5	0.0	-0.8	0.6	-0.5	0.4	-2.4	0.7	0.5	0.2	0.2	0.5	0.8	0.2	0.5	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	5.1	0.5	0.6	-0.1	0.2	0.5	-0.2	0.5	-0.3	0.8	0.4	-0.1	0.4	0.3	0.4	-2.3	0.6	0.6
Osteoporosis (self-reported)	0.5	0.7	1.5	0.7	1.1	0.6	1.1	0.6	0.7	0.9	1.0	0.6	0.7	1.2	0.9	0.3	0.2	1.0	0.8	0.6
Medication: Aspirin	0.5	0.7	3.0	0.6	0.3	0.6	-0.3	0.9	-0.7	0.3	-1.3	1.1	0.5	-0.2	0.3	0.5	1.0	-1.7	0.6	0.9
Wears glasses or contact lenses	0.5	0.5	3.5	0.2	0.7	0.3	-1.2	0.1	-1.9	0.4	0.0	0.1	0.4	1.6	0.7	-0.1	-0.2	-0.5	0.1	0.2
Ever smoked	0.5	0.8	4.4	0.5	0.7	0.2	1.5	0.3	0.8	0.9	2.1	1.0	0.4	1.0	0.6	1.2	0.2	-0.2	0.9	0.1
Heart disease (siblings)	0.5	0.6	3.0	0.6	0.5	-0.2	-1.3	0.5	-1.4	0.3	-1.7	0.6	0.4	0.9	0.3	0.0	0.6	-0.2	0.3	0.5
Alzheimer’s Disease (in mother)	0.4	0.4	1.2	0.7	0.3	0.8	-0.7	0.6	-0.9	0.4	-0.6	0.8	0.5	0.6	0.3	0.9	1.1	-0.2	0.5	0.8
Crohns Disease (2017)	0.4	0.9	1.9	-1.1	-1.2	-0.4	0.3	-1.2	0.6	-1.1	0.6	-1.1	-1.0	-1.3	-1.1	-0.8	-1.0	-0.8	-1.0	-1.4
Triglycerides	0.4	0.6	3.5	0.6	0.5	1.2	0.8	0.7	1.9	0.4	-0.5	0.3	0.5	-1.0	0.3	-0.2	0.7	0.6	0.5	0.2
Heart attack	0.4	0.5	1.9	0.3	-0.1	0.3	-0.9	0.4	-0.7	0.1	-0.9	1.0	0.4	0.9	0.1	1.1	1.0	0.3	0.3	1.4
Time employed in main current job	0.4	0.4	1.1	-0.6	-0.5	0.3	-1.0	-0.6	-0.8	-0.6	-0.7	-0.8	-0.6	-0.7	-0.7	-1.1	-0.5	0.3	-0.6	-0.4
Worrier / anxious feelings	0.4	0.8	7.3	0.4	0.3	-0.3	-1.6	0.2	-2.7	0.3	-0.5	0.1	0.4	1.2	0.5	0.5	0.5	0.2	0.0	0.2
Illnesses of mother	0.4	0.4	2.4	-0.5	-0.6	-0.9	0.1	-0.5	0.0	-0.4	1.6	-0.5	-0.5	-0.4	-0.4	-0.3	-0.5	0.4	-0.5	-1.3
Birth weight of first child	0.4	0.7	1.3	-1.1	-0.9	0.1	-0.9	-1.1	-0.5	-1.0	-0.6	-0.7	-1.1	-0.0	-1.1	-0.6	-1.0	0.5	-1.0	-0.9
Glaucoma (self-reported)	0.4	0.4	1.7	0.7	1.1	0.1	0.9	0.4	1.3	0.9	0.5	0.2	0.4	0.3	0.8	-0.5	-0.1	-0.2	0.7	-0.0
Number of full brothers	0.4	0.5	4.1	0.5	0.7	0.2	0.1	0.3	-0.2	0.7	0.6	-0.5	0.5	0.5	0.8	-0.2	0.1	2.0	0.2	-0.7
Migraine (self-reported)	0.4	0.5	2.0	0.1	0.1	-1.3	1.0	-0.0	1.2	0.2	1.4	0.4	-0.0	-0.5	0.0	-0.1	0.0	-1.2	0.2	0.1
Medication: Omeprazole	0.4	0.5	2.8	0.7	0.6	0.7	0.1	0.7	-0.0	0.6	0.3	0.7	0.7	0.6	0.7	0.3	0.8	0.4	0.6	1.7
Medication: Seretide 50 evohaler	0.4	0.5	1.9	-0.7	-1.1	-0.6	0.1	-0.6	0.3	-0.7	1.4	-0.5	-0.6	-0.9	-0.6	-0.3	-0.1	-0.8	-0.7	-0.0
Alcohol intake frequency.	0.4	0.9	2.9	0.9	0.5	0.3	0.6	1.0	-0.5	0.7	1.2	1.4	1.0	0.8	0.7	1.7	1.4	-0.1	1.0	1.2
Leg pain on walking	0.4	0.5	2.0	0.6	1.2	0.2	0.3	0.5	-0.3	1.0	0.6	0.6	0.7	1.4	1.1	0.0	-0.1	-0.1	0.8	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.5	0.2	0.1	0.2	1.0	0.2	1.4	0.1	0.7	0.4	0.1	-0.1	-0.2	1.2	0.2	1.6	0.3	0.4
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.2	0.6	0.4	0.9	0.4	0.5	0.6	0.6	-0.8	0.5	0.8	0.6	0.6	0.3	0.9	0.5	0.7	1.1
Long-standing illness, disability or infirmity	0.4	0.6	2.8	-0.5	-0.8	-0.7	-1.7	-0.5	-1.1	-0.7	-1.6	-0.3	-0.6	-0.1	-0.7	-0.2	-0.1	-0.7	-0.5	-0.3
Ever had bowel cancer screening	0.4	0.4	1.7	-0.3	-0.5	-0.7	-1.1	-0.3	-1.0	-0.6	-1.3	-0.2	-0.3	-0.3	-0.5	-0.4	-0.2	-0.9	-0.3	-0.7
Eye problems/disorders: Cataract	0.4	0.4	2.2	-0.4	-0.4	-1.0	-0.9	-0.4	-0.5	-0.4	-1.5	-0.6	-0.5	-0.8	-0.4	-0.5	-0.3	-0.6	-0.4	-0.3
Hearing aid user	0.4	0.4	1.5	-0.3	-0.0	0.8	-1.0	-0.5	-1.2	-0.2	0.8	-0.7	-0.2	0.4	-0.0	-0.4	-0.7	1.1	-0.5	-0.4
Medication: Bendroflumethiazide	0.4	0.5	3.5	0.1	-0.1	-0.6	1.2	0.1	1.9	0.1	0.9	-0.0	0.2	-0.2	0.0	0.9	0.5	1.4	0.2	0.3
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.2	-0.4	-0.3	-0.8	-1.5	-0.3	-1.1	-0.5	-1.2	-0.3	-0.5	-0.1	-0.4	-0.3	-0.3	-0.6	-0.5	-0.3
Vascular/heart problems diagnosed by doctor	0.4	1.2	5.1	-0.8	-0.2	0.7	-1.3	-0.9	-2.3	-0.6	0.5	-1.2	-0.6	0.4	-0.1	-1.7	-1.6	-0.5	-1.0	-1.3
Ovarian Cancer	0.3	0.5	1.9	0.6	0.5	1.0	1.0	0.5	1.4	0.4	-0.1	0.4	0.5	-0.4	0.3	0.8	0.8	0.5	0.6	0.3
Blood Red Count	0.3	2.9	26.1	0.5	0.4	1.3	-3.1	0.7	-5.1	-0.1	-2.2	0.5	0.5	0.5	0.3	0.0	0.7	-1.6	-0.3	1.5
Blood White Count	0.3	2.0	8.3	-0.9	-1.1	-0.8	-2.7	-0.9	-1.7	-1.3	-2.9	-0.9	-0.9	-0.9	-1.2	-1.8	-0.4	-1.3	-1.0	-0.6
BMI	0.3	1.6	9.2	-0.4	-0.5	-1.6	0.1	-0.2	1.8	-0.6	-3.0	0.0	-0.3	-1.9	-0.8	-1.2	0.0	-2.2	0.0	0.2
Allergy or Eczema	0.3	0.8	4.7	-0.0	-0.1	0.1	-1.8	0.1	-2.2	-0.2	-2.0	-0.4	0.1	-0.3	0.1	-0.3	0.3	-0.9	-0.3	-0.2
Cardiovascular Disease	0.3	1.0	3.0	1.1	0.6	-0.1	0.7	1.0	1.2	0.8	-0.2	1.5	0.9	-0.4	0.5	1.4	1.7	-0.3	1.3	1.4
Number of treatments/medications taken	0.3	0.5	2.0	0.5	-0.2	-0.5	-0.8	0.5	-0.8	0.0	-1.1	0.9	0.4	0.2	-0.1	0.7	1.4	-0.1	0.4	0.8
Medication for hormone replacement therapy	0.3	0.3	1.2	0.5	0.4	0.5	0.2	0.5	-0.6	0.5	1.1	0.5	0.4	0.4	0.6	-0.1	0.4	-1.0	0.5	-0.2
Trunk fat percentage	0.3	1.1	7.6	-0.8	-0.9	-1.2	-1.4	-0.6	-0.5	-0.9	-2.8	-0.3	-0.8	-0.7	-1.1	-0.8	-0.5	-0.8	-0.7	-0.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.5	-0.2	0.1	0.6	-0.5	-0.1	-0.4	0.1	-0.9	-0.6	0.0	0.4	0.1	-0.0	-0.4	1.6	-0.2	-0.0
High blood pressure	0.3	0.9	6.6	0.4	-0.1	-0.6	1.5	0.5	2.6	0.3	0.1	0.7	0.3	-0.6	-0.2	1.3	1.2	0.9	0.6	0.8
Falls in the last year	0.3	0.4	1.0	0.7	0.5	0.3	0.2	0.7	-0.3	0.5	-0.5	0.6	0.6	0.7	0.6	1.0	0.7	0.3	0.7	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.8	-0.6	-0.7	-1.3	-0.7	-0.6	0.5	-0.6	-1.7	-0.3	-0.5	-0.6	-0.6	-0.4	-0.2	-0.0	-0.4	0.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.8	0.4	0.8	-0.2	-0.1	0.3	-0.8	0.4	-0.6	0.4	0.3	1.3	0.4	0.4	-0.1	1.1	0.5	0.7
Gout (self-reported)	0.3	0.5	1.1	0.6	0.8	1.0	0.2	0.7	-0.0	0.7	-0.4	0.4	0.8	0.9	0.9	0.4	0.4	1.0	0.5	0.6
Medication: Amlodipine	0.3	0.4	1.4	-0.2	-0.7	0.0	1.2	-0.2	1.1	-0.5	1.1	0.0	-0.2	-0.4	-0.5	0.3	0.3	1.0	-0.0	0.3
High blood pressure (siblings)	0.3	0.4	3.5	0.2	0.3	-1.0	-0.5	0.3	-0.0	0.1	-1.9	0.1	0.1	-0.4	0.1	-0.2	0.2	-1.1	0.2	0.6
Number of children fathered	0.3	0.3	1.2	-0.5	-0.4	0.2	-0.7	-0.6	0.1	-0.6	-1.1	-0.6	-0.6	-0.1	-0.5	-0.6	-0.6	-0.5	-0.5	0.1
Pulse wave peak to peak time	0.3	0.4	0.8	-0.6	-0.6	-0.8	0.2	-0.6	0.6	-0.5	0.5	-0.5	-0.7	-0.7	-0.7	-0.4	-0.6	0.2	-0.6	-0.9
Medication: Blood pressure	0.3	0.5	3.2	-0.4	-0.7	-0.9	0.7	-0.2	1.8	-0.5	0.4	0.1	-0.6	-1.1	-0.8	0.3	-0.0	-0.3	-0.1	0.4
Angina (self-reported)	0.3	0.4	3.2	-0.3	-0.6	-0.6	-0.9	-0.2	-0.3	-0.5	-1.8	-0.0	-0.2	-0.2	-0.4	-0.5	0.2	-0.9	-0.1	0.1
Suffer from ‘nerves’	0.3	0.4	1.7	0.6	0.4	-0.4	-0.6	0.5	-1.3	0.6	-0.6	0.6	0.6	0.9	0.6	0.8	0.8	-0.2	0.4	0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.5	0.6	0.5	1.1	-0.1	0.6	-0.7	0.5	-1.2	0.4	0.8	0.2	0.6	0.3	0.8	0.1	0.6	0.6
Hypertension (Self-reported)	0.3	0.7	5.5	0.1	-0.5	-0.8	1.3	0.1	2.3	-0.1	0.0	0.5	-0.1	-0.9	-0.6	1.1	0.9	0.4	0.3	0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.8	0.3	0.1	1.1	-0.6	0.2	-1.0	0.1	0.6	0.2	0.5	0.8	0.3	0.6	0.7	1.3	0.0	0.3
Loneliness, isolation	0.3	0.4	1.5	0.4	0.2	-0.3	1.2	0.6	1.2	0.5	-0.2	1.0	0.4	0.3	0.2	0.8	0.6	0.0	0.7	0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	1.4	-0.2	0.0	0.7	-0.5	-0.2	-1.2	-0.1	1.2	-0.4	0.0	1.0	0.2	-0.4	-0.6	0.8	-0.4	-0.3
Guilty feelings	0.3	0.4	1.8	0.5	0.4	-0.4	0.7	0.4	-0.3	0.5	-0.1	0.9	0.6	1.3	0.5	0.8	0.6	-0.7	0.8	0.8
Mother’s age at death	0.3	0.4	1.9	-0.5	-0.4	0.6	-1.1	-0.4	-1.4	-0.6	-0.6	-0.6	-0.4	-0.1	-0.4	-0.3	-0.5	-0.2	-0.7	0.2
Medication: Lisinopril	0.3	0.4	2.0	0.2	0.1	-0.6	0.5	0.3	1.4	0.3	-0.5	0.6	0.2	-0.4	-0.1	0.7	0.6	-0.3	0.5	1.2
Illnesses of father: High blood pressure	0.3	0.4	3.3	-0.1	-0.2	-0.9	0.8	-0.1	1.8	-0.1	-0.4	0.0	-0.3	-1.0	-0.5	0.6	0.0	-0.2	0.1	0.5
Ever depressed for a whole week	0.3	0.3	2.1	0.3	0.1	0.3	-0.9	0.1	-1.4	0.1	-1.4	0.1	0.2	0.4	0.0	0.0	0.5	-0.1	0.2	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	2.2	0.6	0.3	0.5	-0.1	0.5	-0.2	0.3	-0.0	0.6	0.5	0.2	0.4	0.3	0.8	0.3	0.4	1.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	0.1	-0.3	0.2	-1.0	0.2	-0.7	-0.1	-0.9	0.7	0.2	0.8	-0.1	0.9	0.7	0.5	0.1	1.2
Neuroticism (2016)	0.2	0.4	1.7	0.2	0.0	-1.0	-0.8	-0.1	-1.2	0.0	-1.3	0.2	0.1	0.4	-0.1	-0.0	0.5	-0.9	0.1	0.3
Blood Platelet Count	0.2	1.7	13.9	-0.0	-0.1	-1.9	-2.1	-0.0	-3.7	-0.2	-0.6	-0.3	0.2	1.0	0.5	-1.1	-0.3	-2.1	-0.3	0.1
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.8	-0.3	-0.2	-0.8	0.1	-0.2	0.8	-0.3	-0.0	-0.3	-0.2	-0.8	-0.2	-0.9	-0.3	-1.7	-0.1	-0.1
Ever had hysterectomy (womb removed)	0.2	0.2	0.9	-0.0	-0.6	0.7	0.7	0.1	0.8	-0.5	0.9	0.3	0.1	-0.4	-0.3	-0.2	0.5	0.0	-0.1	0.1
Current tobacco smoking	0.2	0.3	2.1	-0.2	-0.3	-0.3	1.1	-0.2	0.7	-0.0	1.5	0.2	-0.3	0.4	-0.1	-0.1	-0.3	0.1	0.0	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.1	-0.2	-0.3	-0.9	-0.8	-0.3	-0.7	-0.2	-1.1	0.1	-0.1	0.4	-0.3	0.2	0.1	-0.2	0.0	0.2
Body mass index (BMI)	0.2	0.8	6.3	0.1	-0.1	-1.1	0.2	0.4	1.2	0.0	-2.5	0.7	0.1	-0.9	-0.2	-0.3	0.5	-1.5	0.5	0.7
Financial difficulties in last 2 years	0.2	0.2	1.7	-0.4	-0.3	-1.3	0.2	-0.4	0.6	-0.3	0.1	0.2	-0.4	-0.4	-0.5	-0.2	-0.4	-0.2	-0.1	-0.6
Pain all over the body in last month	0.2	0.2	0.9	-0.0	-0.4	-0.3	-1.0	-0.3	-0.7	-0.2	-0.3	-0.1	-0.2	-0.2	-0.3	0.5	0.4	0.3	-0.2	-0.5
Medication: Ramipril	0.2	0.2	1.4	-0.2	-0.3	-0.8	-0.6	-0.2	-0.4	-0.2	-0.0	0.3	-0.4	-0.2	-0.3	0.4	0.1	-1.2	-0.1	0.2
Medication: Simvastatin	0.2	0.2	1.6	0.2	-0.1	1.3	0.3	0.1	0.1	-0.0	0.2	0.3	0.2	-0.4	-0.0	0.0	0.6	-1.0	0.2	0.6
Number of live births	0.2	0.3	1.3	0.7	0.5	0.7	0.5	0.6	-0.3	0.6	0.8	0.5	0.5	0.3	0.4	0.4	0.7	1.1	0.6	0.2
Happiness	0.2	0.3	2.5	-0.3	-0.4	-1.0	-0.4	-0.2	-0.5	-0.2	-0.6	0.3	-0.2	-0.3	-0.3	0.2	-0.1	-1.6	-0.1	-0.2
Medication: Cholesterol lowering	0.2	0.3	1.2	0.3	0.3	0.7	-0.3	0.4	-0.6	0.4	0.1	0.7	0.2	0.3	0.2	0.1	0.4	-0.9	0.6	1.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.1	-0.3	-0.3	-0.1	-0.6	-0.4	-0.9	-0.3	-1.0	-0.6	-0.0	-0.0	-0.0	-0.4	-0.2	-0.2	-0.5	-1.1
Exposure to tobacco smoke outside home	0.2	0.3	2.4	-0.5	-0.6	-1.6	-0.3	-0.5	-0.2	-0.5	-0.1	-0.0	-0.6	-0.0	-0.7	0.7	-0.2	-0.3	-0.4	0.1
Shortness of breath walking on level ground	0.2	0.2	0.8	0.0	-0.1	-0.9	0.5	0.0	0.7	0.1	0.4	0.6	0.0	0.1	-0.2	0.4	0.3	-0.7	0.2	0.5
Mood swings	0.2	0.4	1.4	0.5	0.4	-1.0	0.3	0.4	-0.2	0.6	0.1	0.7	0.4	0.9	0.4	1.2	0.5	0.3	0.7	0.3
Friendships satisfaction	0.2	0.3	1.9	-0.1	-0.3	-0.7	0.1	-0.1	0.7	-0.1	-1.0	0.3	-0.2	-0.7	-0.4	0.0	0.2	-1.4	0.1	0.1
Smoking status: Current	0.2	0.4	3.1	0.2	0.1	-0.0	1.3	0.1	0.5	0.3	1.8	0.5	0.1	0.9	0.2	0.3	0.0	0.5	0.3	-0.1
Number of self-reported non-cancer illnesses	0.2	0.4	1.7	-0.2	-0.8	-1.2	-0.7	-0.3	-0.5	-0.5	-1.3	0.0	-0.4	-0.5	-0.7	-0.1	0.4	-0.8	-0.3	-0.3
Miserableness	0.2	0.4	1.0	0.7	0.7	-0.4	0.7	0.5	0.3	0.7	-0.1	1.0	0.6	0.9	0.5	0.4	0.6	-0.7	1.0	0.6
Financial situation satisfaction	0.2	0.3	1.2	0.3	0.5	-0.5	0.6	0.2	-0.1	0.7	0.3	0.6	0.3	1.1	0.5	0.8	0.1	0.4	0.5	-0.0
Supplements: Calcium	0.2	0.2	0.5	-0.3	-0.7	-0.5	-0.2	-0.3	0.5	-0.5	-0.7	-0.1	-0.4	-0.6	-0.6	0.4	0.1	0.1	-0.3	-0.5
Blood Eosinophil Count	0.1	0.5	3.5	0.2	-0.1	-1.9	-0.3	0.1	-0.3	-0.3	-1.2	0.3	0.0	-1.6	-0.4	0.0	0.6	-0.3	0.1	0.4
Average weekly spirits intake	0.1	0.2	1.2	-0.0	-0.1	0.1	-0.6	0.0	-0.7	-0.1	-1.1	-0.0	-0.2	0.2	-0.2	-0.0	-0.0	-0.6	-0.0	-0.4
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.6	-0.3	-0.3	-1.2	-0.1	-0.2	0.1	-0.3	-0.6	0.3	-0.3	0.0	-0.5	0.1	-0.2	-0.7	0.0	-0.0
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.7	-0.3	-0.3	-0.7	0.0	-0.3	-0.1	-0.3	0.2	0.1	-0.1	-0.1	-0.3	-0.2	-0.1	-0.8	-0.0	-0.0
Angina	0.1	0.2	1.6	0.1	-0.2	-0.1	-0.4	0.2	0.0	-0.1	-1.3	0.4	0.2	0.1	-0.0	-0.0	0.5	-0.6	0.3	0.4
Taking other prescription medications	0.1	0.1	0.4	0.1	-0.3	-0.6	0.1	0.1	0.1	-0.1	-0.0	0.3	0.1	-0.2	-0.1	0.1	0.6	-0.7	0.1	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	-0.4	-0.2	-0.3	0.4	-0.2	0.5	-0.2	0.6	-0.4	-0.4	-0.0	-0.1	-0.2	-0.6	-0.5	-0.3	-0.2
Headache pain in last month	0.1	0.2	1.3	-0.1	0.4	-1.1	0.2	-0.1	0.3	0.3	0.7	-0.2	-0.2	0.3	0.3	-0.3	-0.6	-0.3	0.0	-0.2
Medication: Ibuprofen	0.1	0.1	0.3	-0.4	-0.5	-0.2	-0.4	-0.3	-0.1	-0.5	-0.2	0.1	-0.4	-0.3	-0.5	-0.1	-0.1	0.1	-0.4	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.6	0.4	0.2	0.8	0.5	0.4	0.3	0.4	0.6	0.3	0.4	-0.1	0.4	0.3	0.6	0.2	0.3	-0.2
Breast cancer (self-reported)	0.1	0.1	0.7	0.2	0.3	-0.5	-0.2	0.3	0.1	0.4	-0.1	0.5	0.2	0.8	0.2	0.9	0.1	-0.3	0.2	-0.1
Medication: Blood pressure	0.1	0.2	1.2	-0.3	-0.6	-0.8	0.5	-0.3	1.1	-0.3	-0.2	0.0	-0.1	-0.4	-0.4	0.5	0.4	-0.3	-0.1	0.4
Medication: Paracetamol	0.1	0.1	0.4	0.1	0.1	-0.5	0.2	0.1	0.5	0.2	-0.0	0.5	0.1	-0.6	-0.1	0.3	0.5	-0.7	0.4	0.6
Fractured/broken bones in last 5 years	0.1	0.1	0.6	-0.0	0.1	0.1	0.8	-0.0	0.5	-0.0	0.6	-0.0	-0.1	-0.5	-0.1	-0.2	-0.2	-0.3	-0.0	-0.2
Diastolic blood pressure, automated reading	0.1	0.2	1.0	0.3	-0.1	-1.0	-0.1	0.2	0.5	-0.1	-0.5	0.6	0.1	-0.7	-0.3	0.3	0.7	-0.6	0.2	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.2	-0.1	-0.1	0.3	-0.2	0.0	-0.0	-0.1	-0.1	0.4	-0.1	0.3	-0.1	0.3	0.0	-0.3	-0.1	0.3

Hub : Genes

UQCC1

Models

Trait associations