Hub : Genes

CEP250

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0230 0.0130 4.4e-03 -0.001 0.004 0.002 0.003 -0.001 3.8e-01 1.0e-01 1.7e-01 1.2e-01 5.2e-01
2 GTEx Brain Caudate basal ganglia 0.2600 0.1360 3.0e-03 0.002 NA 0.076 NA 0.051 2.7e-01 NA 3.2e-03 NA 1.4e-02
3 GTEx Brain Cerebellar Hemisphere 0.5090 0.1010 8.6e-10 0.402 NA 0.339 NA 0.357 2.0e-11 NA 1.6e-09 NA 4.7e-10
4 GTEx Brain Cerebellum 0.3900 0.1000 2.3e-09 0.163 NA 0.243 NA 0.239 1.5e-05 NA 8.8e-08 NA 1.1e-07
5 GTEx Brain Cortex 0.1370 0.0570 3.0e-04 0.165 NA 0.154 NA 0.152 2.6e-05 NA 4.9e-05 NA 5.7e-05
6 GTEx Brain Frontal Cortex BA9 0.4656 0.1203 1.1e-05 0.175 NA 0.010 NA 0.072 2.1e-05 NA 1.7e-01 NA 6.0e-03
7 GTEx Brain Hypothalamus 0.1800 0.0950 2.1e-03 -0.012 NA -0.008 NA -0.001 7.9e-01 NA 5.4e-01 NA 3.4e-01
8 GTEx Brain Nucleus accumbens basal ganglia 0.1540 0.0850 3.6e-03 0.093 NA 0.010 NA 0.047 1.8e-03 NA 1.7e-01 NA 2.1e-02
9 GTEx Brain Putamen basal ganglia 0.1930 0.1130 9.6e-03 -0.012 NA -0.012 NA -0.009 8.8e-01 NA 8.1e-01 NA 5.9e-01
10 GTEx Esophagus Mucosa 0.2870 0.0890 2.1e-04 -0.001 NA -0.004 NA -0.003 4.0e-01 NA 9.3e-01 NA 5.3e-01
11 GTEx Esophagus Muscularis 0.1330 0.0600 5.1e-04 0.037 NA 0.018 NA 0.025 2.7e-03 NA 2.7e-02 NA 1.1e-02
12 GTEx Liver 0.2980 0.1010 7.5e-03 -0.006 NA -0.005 NA -0.002 5.3e-01 NA 4.7e-01 NA 3.7e-01
13 GTEx Muscle Skeletal 0.0900 0.0388 7.0e-07 0.039 NA 0.063 NA 0.067 1.1e-04 NA 8.2e-07 NA 3.6e-07
14 GTEx Nerve Tibial 0.6105 0.0760 2.6e-11 0.054 NA 0.022 NA 0.049 1.1e-04 NA 9.6e-03 NA 2.1e-04
15 ROSMAP Brain Pre-frontal Cortex 0.1454 0.0413 1.5e-13 0.144 0.116 0.125 0.126 0.130 4.0e-18 1.1e-14 1.0e-15 6.5e-16 2.3e-16
16 YFS Blood 0.1453 0.0423 0.0e+00 0.124 0.121 0.122 0.128 0.132 3.1e-38 1.5e-37 1.1e-37 1.2e-39 9.2e-41
17 TCGA Breast Invasive Carcinoma 0.0145 0.0081 1.4e-04 0.020 0.019 0.019 NA 0.019 4.3e-05 5.8e-05 6.3e-05 NA 6.3e-05
18 TCGA Head and Neck Squamous Cell Carcinoma 0.0200 0.0118 1.3e-03 0.013 0.025 0.019 NA 0.017 1.3e-02 8.0e-04 2.9e-03 NA 4.6e-03
19 TCGA Kidney Renal Clear Cell Carcinoma 0.0275 0.0192 1.9e-03 0.006 0.029 0.020 NA 0.018 5.9e-02 2.6e-04 2.2e-03 NA 3.6e-03
20 TCGA Liver Hepatocellular Carcinoma 0.0850 0.0510 2.4e-04 0.064 0.049 0.011 NA 0.056 5.7e-04 2.4e-03 9.6e-02 NA 1.2e-03
21 TCGA Lung Adenocarcinoma 0.0184 0.0115 3.4e-03 0.019 0.017 0.012 NA 0.015 2.6e-03 4.0e-03 1.2e-02 NA 6.1e-03
22 TCGA Prostate Adenocarcinoma 0.0800 0.0326 6.8e-14 0.153 0.141 0.148 NA 0.144 9.7e-16 1.5e-14 3.1e-15 NA 6.8e-15
23 TCGA Testicular Germ Cell Tumors 0.1010 0.0700 9.4e-03 -0.001 0.046 0.001 NA 0.011 3.6e-01 9.8e-03 3.0e-01 NA 1.3e-01
24 TCGA Thyroid Carcinoma 0.0450 0.0270 4.5e-05 0.030 0.042 0.038 NA 0.034 5.9e-04 5.8e-05 1.3e-04 NA 2.9e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 0.8 1.3 3.1 -1.8 -1.4 -0.7 -0.6 -0.8 -1.1 -1.2 -0.5 -1.4 1.8 -1.7 0.0 -1.3 -0.5 -1.1 -0.9 0.8 1.1 1.0 0.9 0.7 1.2 1.3 1.4
Bipolar Disorder or Schizophrenia 0.4 0.9 8.3 -2.2 -0.7 0.1 0.5 -0.1 -0.3 -0.6 0.2 -0.2 2.9 -1.1 -1.6 -0.9 -0.2 -0.0 0.0 -0.2 0.5 0.5 0.2 -0.3 0.1 1.0 0.8
Depressed Affect (Nagel 2018) 0.1 0.2 1.2 -1.0 -0.5 -0.6 -0.0 -0.1 -0.4 -0.4 -0.5 -0.5 -0.4 -0.8 1.1 0.4 0.5 0.2 -0.3 0.1 -0.3 -0.2 0.2 0.1 -0.1 -0.4 -0.1
Depression (Nagel 2018) 1.8 2.7 5.8 -2.4 -1.6 -2.1 -1.5 -1.8 -2.1 -1.6 -1.9 -1.7 1.0 -1.5 0.5 -1.8 0.1 -1.6 -1.8 1.5 1.5 1.4 1.7 1.5 1.5 1.8 1.6
Intelligence (Savage-Jansen 2018) 4.3 13.2 24.6 -5.0 -3.5 -4.2 -3.3 -4.1 -4.2 -4.4 -4.2 -4.5 2.5 -3.2 0.5 -3.2 -2.1 -3.7 -4.3 3.8 3.5 2.9 3.7 3.6 3.5 2.7 3.6
Neuroticism (Nagel 2018) 0.3 0.7 2.7 -1.6 -0.9 -1.2 -0.8 -0.8 -0.9 -0.4 -1.0 -0.9 -0.5 -1.1 0.7 0.0 -0.7 -0.7 -1.0 0.8 0.2 0.5 0.8 1.0 0.7 -0.1 0.2
Schizophrenia (2018) 0.3 0.6 5.2 -1.3 0.3 0.7 1.3 0.5 0.6 0.2 0.6 0.9 2.3 0.1 0.0 -0.1 0.2 0.8 0.7 -0.9 -0.3 -0.2 -0.5 -1.0 -0.8 0.2 -0.1
Schizophrenia vs Biploar Disorder 2.1 2.8 4.8 0.8 1.7 2.1 1.7 1.7 2.0 1.9 1.9 1.6 -1.3 1.3 0.0 2.1 0.3 1.8 1.6 -1.8 -1.6 -1.5 -1.9 -1.9 -1.9 -2.2 -1.6
Worry (Nagel 2018) 0.6 1.3 5.3 -2.3 -1.1 -1.4 -1.1 -1.3 -0.9 -0.4 -1.3 -0.7 0.3 -1.2 0.4 -0.8 -1.1 -1.4 -1.5 1.2 0.8 1.1 1.3 1.4 1.2 1.0 0.8
Alzheimer’s Disease (in mother) 0.5 0.5 1.9 0.8 1.1 0.5 1.0 0.6 0.4 1.0 0.5 1.2 -0.1 1.4 -0.5 0.4 1.0 0.4 0.7 -0.6 -0.7 -0.8 -0.5 -0.5 -0.5 0.1 -0.7
Alzheimer’s Disease (in father) 2.0 2.1 6.9 2.2 1.0 1.7 1.9 1.7 1.1 1.3 1.4 0.7 -2.6 1.0 0.7 1.7 0.1 1.3 1.5 -1.2 -1.4 -1.2 -1.3 -1.4 -1.3 -1.9 -1.3
Alzheimer’s Disease (including proxy) 1.2 1.8 5.2 2.3 1.1 1.4 1.9 1.4 0.9 1.6 1.2 1.2 -2.2 1.3 0.1 1.5 0.4 0.9 1.3 -1.0 -1.4 -1.3 -1.0 -1.0 -1.0 -1.1 -1.3
Crohns Disease (2017) 0.1 0.2 0.9 0.1 -0.2 -0.3 -0.7 -0.1 -0.5 -1.0 -0.4 -0.7 -0.5 -0.2 -0.2 -0.6 -0.4 -0.0 -0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.5 0.2
Irritable Bowel Disease (IBD) 0.8 1.9 4.0 -2.0 -1.5 -1.3 -1.6 -1.3 -1.4 -1.6 -1.5 -1.0 0.9 -1.6 -0.9 -1.4 -1.9 -1.0 -1.2 1.1 1.3 1.6 1.4 1.1 1.0 1.3 1.4
Ulcerative Colitis (UC) 1.2 2.2 8.0 -2.8 -1.5 -1.2 -1.1 -1.6 -1.1 -1.2 -1.4 -0.8 1.7 -1.7 -1.0 -1.4 -2.0 -1.3 -1.5 1.3 1.6 1.7 1.4 1.3 1.3 1.2 1.6
Major Depression (MDD) 0.5 0.6 1.9 0.0 -0.2 0.3 1.4 1.0 0.6 0.5 0.4 0.3 -0.2 -0.5 1.2 0.9 0.3 1.1 1.0 -0.9 -1.4 -1.2 -0.5 -0.8 -0.8 -0.3 -0.9
Reaction Time 3.5 6.7 11.4 3.4 2.8 3.0 2.6 2.7 2.8 2.8 3.3 2.3 -1.1 2.6 2.0 1.8 3.3 2.4 2.7 -2.6 -2.5 -2.7 -2.9 -2.6 -2.2 -1.4 -2.5
Verbal and Numeric Reasoning (VNR) 3.2 7.7 17.9 -4.2 -2.9 -3.1 -2.3 -3.0 -3.0 -3.2 -3.2 -3.4 2.5 -2.6 0.2 -2.3 -1.6 -2.8 -3.2 2.9 2.7 2.4 2.8 2.7 2.7 2.0 2.8
Breast Cancer 0.4 1.0 7.2 2.7 1.0 0.3 1.3 0.4 0.6 0.1 0.2 1.1 0.1 2.0 0.9 0.4 2.7 -0.0 0.3 -0.1 -0.1 -0.7 -0.3 -0.1 -0.2 0.0 -0.3
Ovarian Cancer 0.9 1.2 5.4 1.8 1.3 0.6 0.9 1.0 0.4 0.4 0.5 0.7 -2.1 1.9 -0.7 0.5 2.3 0.7 0.9 -0.8 -0.9 -1.0 -0.8 -0.7 -0.7 -0.2 -1.0
Prostate Cancer 3.0 4.3 9.2 1.9 1.4 1.9 1.8 2.0 1.8 1.9 1.9 1.0 -2.7 1.5 0.5 3.0 0.7 2.2 1.7 -2.1 -2.6 -2.6 -2.1 -2.1 -2.3 -3.0 -2.5
Age at First Birth 0.4 0.6 1.3 -1.1 -0.4 -0.8 -0.1 -0.6 -1.0 -0.7 -1.0 -0.8 1.0 -0.1 -0.3 -0.7 -1.1 -0.6 -0.7 0.6 1.0 0.9 0.8 0.6 0.7 0.8 1.0
Bipolar Disorder (2011) 0.5 0.5 5.7 -0.8 0.8 -0.4 -0.3 -0.2 -0.0 -1.1 -0.4 0.4 2.4 0.5 0.0 -0.7 1.1 -0.1 -0.1 0.0 0.6 0.3 -0.1 0.1 -0.1 0.7 0.1
Body Mass Index (BMI) (2010) 0.2 0.2 2.1 -0.4 0.4 0.0 0.2 0.1 -0.3 -0.2 0.2 -0.9 -0.9 0.5 0.1 -0.6 1.4 -0.0 0.1 0.1 0.2 -0.2 -0.2 -0.0 0.1 0.2 0.2
Coronary Artery Disease (CAD) 1.7 2.0 7.4 -2.7 -1.3 -1.4 -0.5 -1.0 -1.8 -1.3 -1.1 -1.8 1.5 -2.2 2.3 -1.4 -0.3 -0.7 -0.6 1.1 1.3 1.6 1.3 0.8 1.0 0.9 1.5
Crohns Disease (2012) 0.7 1.2 3.3 -0.7 -0.9 -1.3 -1.8 -1.0 -1.3 -1.5 -1.3 -1.4 -0.6 -0.7 -1.2 -1.2 -0.7 -0.9 -0.9 0.9 1.0 0.9 1.0 0.9 0.9 1.1 1.0
Mean Putamen Volume 0.2 0.3 1.6 -0.7 0.1 0.0 -0.1 -0.6 -0.2 -0.2 0.0 0.2 1.3 0.1 0.3 -0.9 -0.2 -0.5 -0.4 0.4 0.7 0.4 0.1 0.4 0.6 0.9 0.6
Fasting Glucose 0.5 0.6 2.2 -0.4 -0.3 -0.7 -0.3 -0.7 -0.7 -0.6 -0.8 -0.2 1.5 0.0 -1.1 -0.6 0.0 -1.1 -1.0 0.8 0.9 0.7 0.8 0.9 0.8 0.7 0.7
HbA1C 0.5 0.5 1.2 1.1 0.4 0.9 0.8 0.8 0.7 0.1 0.8 0.1 0.5 0.2 -0.4 0.7 0.3 0.6 0.4 -0.8 -1.1 -1.0 -0.7 -0.8 -0.8 -0.7 -1.1
HDL Cholesterol 2.6 4.3 16.3 4.0 2.2 2.0 1.8 2.0 2.5 1.9 2.1 2.7 -1.4 2.3 0.3 2.1 1.9 1.9 2.1 -1.9 -1.7 -1.4 -2.0 -1.8 -1.8 -1.7 -1.9
LDL Cholesterol 6.8 10.7 17.9 3.6 4.2 3.7 3.4 3.3 3.5 3.5 3.7 3.0 -1.2 3.7 0.1 3.4 2.3 3.0 3.3 -3.2 -3.1 -3.6 -3.7 -3.2 -3.2 -3.4 -3.4
Lupus 0.8 1.2 3.3 -1.0 0.1 -0.9 -1.3 -1.2 -0.8 -0.8 -1.0 -1.0 1.7 0.3 -0.9 -0.9 -0.5 -1.2 -1.4 1.3 1.8 1.6 0.7 1.2 1.1 0.1 1.3
Neuroticism (2016) 0.6 0.9 2.4 -1.0 -1.6 -1.1 -1.0 -0.7 -0.8 -0.5 -0.9 -1.4 0.2 -1.5 0.0 -0.8 -0.7 -0.9 -0.8 0.8 0.5 0.7 1.0 0.9 1.0 1.2 0.8
Primary Biliary Cirrhosis 0.1 0.1 1.0 -0.1 0.3 0.1 -0.1 -0.2 0.1 0.4 0.1 0.5 0.3 0.2 -1.0 -0.6 0.1 -0.0 0.1 -0.3 -0.0 -0.1 -0.1 -0.2 -0.1 0.7 -0.0
Rheumatoid Arthritis 0.4 0.5 5.4 -0.1 0.3 0.6 -0.5 -0.3 0.8 0.6 0.7 0.4 0.4 -0.3 2.3 -0.2 -1.9 -0.0 -0.3 -0.2 0.2 0.3 -0.4 -0.2 -0.0 -0.3 -0.0
Schizophrenia (2014) 0.2 0.4 5.3 -1.2 -0.3 0.0 0.5 0.0 0.0 -0.4 -0.1 0.3 2.3 -0.4 0.0 -0.4 -0.0 0.3 0.2 -0.4 0.2 0.3 0.0 -0.4 -0.3 0.5 0.4
Triglycerides 2.5 4.1 8.7 1.7 2.9 2.4 1.9 2.1 2.0 1.5 2.3 1.1 -1.1 2.8 -0.2 1.3 2.2 2.0 1.9 -2.2 -1.8 -2.5 -2.5 -2.3 -2.2 -1.3 -2.0
Type 2 Diabetes (T2D) (2012) 4.5 5.2 9.3 -2.7 -2.4 -2.3 -2.0 -2.4 -2.5 -2.1 -2.4 -3.1 1.4 -2.3 0.0 -1.9 -2.4 -2.5 -2.6 2.6 2.2 2.0 2.4 2.5 2.6 1.7 2.4
Ulcerative Colitis 2.6 3.8 10.1 -3.2 -2.0 -1.7 -2.0 -2.0 -1.5 -2.0 -1.9 -1.3 1.9 -2.2 -1.0 -2.2 -1.8 -1.7 -2.0 1.6 2.2 2.5 1.8 1.6 1.6 2.0 2.1
Blood Eosinophil Count 0.1 0.8 4.9 -2.2 -0.7 -0.1 -0.2 -0.2 -0.9 -1.2 -0.0 -1.9 -0.6 -1.3 1.3 -0.7 -0.1 0.5 -0.1 -0.3 -0.8 -1.0 -0.1 -0.3 -0.5 0.5 -0.7
Blood Platelet Count 1.4 15.7 25.6 -4.7 -5.1 -4.5 -3.4 -4.4 -4.2 -4.2 -4.6 -3.3 0.7 -5.0 3.3 -2.5 -4.1 -4.0 -4.2 4.5 2.8 3.6 4.7 4.7 4.2 2.5 3.1
Blood Red Count 0.2 1.9 6.7 0.9 2.1 1.2 2.0 1.0 1.2 2.0 1.4 1.5 0.8 2.6 1.6 0.6 2.5 0.5 1.2 -0.6 -0.9 -1.2 -1.2 -0.5 -0.7 -0.3 -1.3
Blood White Count 0.0 0.3 1.2 -1.0 -0.3 0.3 0.4 0.0 0.4 1.1 0.7 1.1 0.8 -0.3 -0.2 -0.8 0.5 -0.0 0.6 -0.1 0.2 0.2 0.1 -0.1 0.1 0.9 0.4
Heel T-Score 0.3 2.6 10.0 -3.2 0.7 0.4 2.9 1.2 -0.5 0.2 0.3 -1.1 1.3 1.2 -0.8 1.9 2.2 1.2 0.9 -1.0 -2.5 -2.8 -1.0 -0.8 -1.3 -1.2 -2.3
BMI 0.2 1.4 6.1 -2.2 -1.9 -0.9 0.0 -0.4 -1.1 -1.7 -0.5 -2.4 1.5 -2.5 0.0 -1.0 -0.0 -0.4 -0.5 0.5 0.1 -0.0 0.9 0.4 0.6 1.1 0.7
Height 43.8 844.4 1444.0 -34.2 -23.9 -27.2 -29.5 -30.0 -26.2 -28.5 -28.8 -24.6 27.5 -22.5 -6.2 -37.0 -19.6 -29.2 -30.9 26.7 38.0 36.3 28.2 25.2 28.3 33.3 37.5
Waist Hip Ratio (WHR) 3.2 14.2 34.3 3.7 2.2 2.9 2.8 3.3 3.1 3.8 3.0 2.2 -5.9 2.2 2.9 5.3 0.2 3.7 3.1 -3.1 -5.8 -5.3 -3.3 -2.7 -3.6 -4.8 -5.7
Systolic Blood Pressure 3.4 17.1 34.1 -3.1 -3.4 -3.8 -4.1 -4.4 -3.9 -4.4 -3.9 -2.8 2.5 -3.2 -0.9 -5.7 -2.1 -4.7 -4.1 4.2 5.1 4.9 4.3 4.2 4.7 5.8 5.2
Smoking Status 0.3 0.6 4.7 1.6 -0.3 0.5 0.1 0.6 1.0 0.9 0.6 1.0 -2.2 -0.5 -0.2 0.8 -0.8 0.6 0.8 -0.3 -0.5 -0.0 -0.2 -0.3 -0.2 -0.9 -0.3
Allergy or Eczema 0.1 0.3 1.4 -1.2 -0.1 -0.7 -0.3 -0.3 -0.7 -0.7 -0.9 -0.8 1.1 0.2 0.3 -0.3 -0.3 -0.3 -0.7 0.3 0.2 -0.2 0.3 0.4 0.0 0.5 -0.0
Cardiovascular Disease 0.1 0.2 0.8 0.1 -0.5 -0.3 0.2 -0.1 -0.9 0.2 0.1 -0.7 -0.2 -0.4 -0.6 -0.5 0.9 -0.2 0.2 0.2 -0.4 -0.8 0.3 0.2 0.5 0.8 0.1
Hypothyroidism (self reported) 0.5 1.0 7.1 -0.5 -1.9 0.1 -0.1 -0.2 -0.8 -0.6 -0.2 -0.4 -0.8 -2.6 1.1 -0.7 -2.7 -0.0 0.1 0.1 0.6 1.1 0.7 -0.0 0.3 0.7 1.0
Respiratory disease 2.4 5.3 13.4 -3.2 -2.8 -2.2 -2.2 -2.2 -2.1 -2.2 -2.5 -2.2 0.0 -3.3 -1.6 -2.0 -3.7 -1.9 -2.3 2.2 1.8 2.0 2.4 2.2 2.0 1.8 2.2
Type 2 Diabetes (T2D) (2018) 0.7 1.4 3.6 -1.5 -1.2 -1.7 -1.8 -1.3 -1.5 -1.9 -1.6 -1.5 0.6 -0.9 -0.8 -0.8 -0.4 -1.0 -1.3 1.1 0.8 0.5 1.1 1.0 0.8 0.8 0.8
Lung FEV1/FVC ratio 2.5 12.8 24.7 -5.0 -3.2 -3.4 -3.1 -3.9 -3.7 -3.0 -3.9 -3.1 1.7 -2.9 -0.1 -3.2 -3.8 -3.7 -4.0 3.8 4.6 4.6 3.8 3.5 3.7 2.3 4.6
Lung FVC 14.3 72.7 118.8 9.7 6.2 8.4 8.2 8.8 7.7 10.3 8.5 7.5 -10.3 6.0 0.9 10.7 3.3 8.7 9.1 -8.1 -10.9 -9.9 -8.1 -7.7 -8.3 -9.5 -10.5
Neuroticism 0.9 2.3 6.5 -2.5 -2.1 -1.7 -1.0 -1.2 -1.8 -1.3 -1.7 -2.5 1.0 -2.3 0.1 -1.0 -1.2 -1.1 -1.7 1.3 1.0 1.0 1.6 1.2 1.2 0.9 1.3
Chronotype (morning person) 1.9 4.5 10.1 -2.6 -2.2 -1.7 -2.4 -2.1 -1.3 -2.0 -1.9 -1.6 -0.2 -2.1 1.6 -2.5 -3.2 -2.1 -2.3 1.9 2.3 2.4 2.1 2.0 2.1 2.6 2.2
Hair Pigment 5.6 160.2 461.7 7.6 10.6 10.5 12.1 12.4 12.5 21.5 12.5 11.0 -15.5 12.3 -0.0 15.4 6.0 12.0 12.9 -11.1 -15.8 -13.8 -12.0 -10.1 -11.6 -13.9 -16.1
Tanning 13.2 161.3 428.5 -7.5 -11.3 -10.8 -12.4 -12.5 -11.8 -20.7 -12.8 -9.7 14.0 -12.2 1.4 -15.3 -7.5 -12.4 -13.2 11.5 15.8 14.2 12.4 10.8 12.1 14.5 16.1
Hand grip strength (left) 13.7 36.2 72.4 -7.0 -4.3 -5.2 -6.1 -6.2 -5.3 -5.8 -5.5 -4.6 5.5 -3.5 -2.1 -8.2 -3.5 -6.2 -6.1 5.7 8.5 7.9 5.5 5.3 6.2 7.2 8.1
Number of treatments/medications taken 0.3 0.5 2.4 -0.9 -1.1 0.0 0.7 0.0 -0.2 0.5 -0.1 -0.2 -1.2 -1.6 1.5 -0.6 -1.2 -0.1 -0.0 -0.0 -0.5 -0.2 0.5 0.1 0.2 1.3 0.0
Average weekly spirits intake 0.6 0.8 2.6 0.3 0.7 1.1 0.7 0.9 0.8 1.1 1.3 0.6 -1.6 0.7 -1.3 0.5 0.3 0.9 1.0 -1.0 -0.7 -0.5 -1.0 -1.0 -0.7 -0.6 -0.6
Sensitivity / hurt feelings 2.5 4.2 7.7 1.3 1.4 2.3 2.3 2.3 2.3 2.8 2.3 1.7 -1.3 1.1 1.2 2.4 0.3 2.4 2.2 -2.2 -2.4 -2.0 -2.2 -2.2 -2.1 -2.3 -2.3
Frequency of depressed mood in last 2 weeks 0.6 0.8 3.0 -1.2 -1.1 -1.3 -0.5 -0.8 -1.5 -0.9 -1.1 -1.2 -0.6 -1.1 1.7 -0.8 0.5 -0.5 -0.7 0.6 0.4 0.4 0.8 0.5 0.5 0.8 0.7
Hearing difficulty/problems: Yes 0.2 0.2 1.3 0.3 0.2 -0.0 -0.0 0.2 0.5 0.6 -0.2 0.5 -0.7 0.4 0.6 0.9 -1.2 0.0 0.0 0.0 -0.6 -0.1 0.0 0.2 -0.2 -0.6 -0.7
Relative age of first facial hair 4.0 8.2 16.6 3.1 2.1 2.9 2.5 3.1 2.9 2.5 3.0 1.8 -2.9 1.9 0.4 3.9 0.3 3.2 2.7 -3.0 -3.3 -3.0 -3.1 -3.0 -3.3 -4.1 -3.5
Other serious medical condition/disability diagnosed by doctor 2.4 3.1 6.1 0.1 0.4 2.0 1.7 2.1 1.6 2.4 1.9 1.1 -1.8 -0.1 0.3 1.8 -1.2 2.3 2.1 -2.4 -2.0 -1.3 -1.8 -2.5 -2.2 -1.7 -1.6
Ever used hormone-replacement therapy (HRT) 0.3 0.4 0.9 -0.1 -0.4 0.3 0.6 0.7 0.2 0.6 0.3 0.8 -0.8 -0.2 -0.8 0.8 0.4 0.7 0.8 -0.6 -1.0 -0.5 -0.3 -0.5 -0.6 -0.4 -0.8
Ever had hysterectomy (womb removed) 0.3 0.3 1.2 1.0 -0.3 -0.0 -0.1 -0.4 0.3 0.2 0.1 0.6 -1.0 0.0 0.7 -0.5 0.1 -0.7 -0.3 0.6 0.1 0.2 0.5 0.8 0.9 1.1 0.2
Systolic blood pressure, automated reading 2.1 6.1 12.6 -2.4 -1.9 -2.4 -2.0 -2.6 -2.2 -2.4 -2.5 -1.1 1.8 -1.6 -1.0 -3.2 -0.9 -3.0 -2.3 2.7 3.0 3.0 2.7 2.7 2.9 3.5 3.1
Eye problems/disorders: Diabetes related eye disease 2.4 2.6 4.2 -1.4 -1.9 -2.1 -1.8 -1.9 -1.6 -1.8 -2.0 -2.0 0.1 -1.6 0.1 -1.4 -1.2 -1.7 -2.0 1.8 1.2 1.1 1.9 1.9 1.7 1.4 1.3
Angina 0.3 0.3 2.9 -1.0 -0.9 -0.8 -0.2 -0.0 -0.4 -0.7 -0.7 -0.2 0.6 -0.7 1.7 -0.2 0.4 -0.1 -0.2 0.1 -0.2 -0.0 0.5 0.2 -0.1 0.5 0.0
Medication for hormone replacement therapy 0.2 0.3 1.2 0.5 0.4 0.3 -0.2 0.5 0.5 0.5 0.5 1.1 -0.5 0.4 -0.4 0.6 0.7 0.4 0.5 -0.4 -0.6 -0.1 -0.5 -0.3 -0.4 -0.5 -0.8
Vitamin and mineral supplements 0.7 0.9 2.3 1.4 1.3 0.8 0.8 0.7 0.9 0.2 1.0 -0.1 0.3 1.3 -0.4 0.9 1.4 0.8 0.5 -0.8 -0.9 -1.5 -1.2 -0.8 -0.8 -1.1 -1.1
Supplements: Zinc 3.1 3.3 8.5 -1.8 -1.4 -1.9 -1.8 -1.8 -1.7 -2.5 -2.0 -0.9 1.3 -1.8 -0.3 -2.6 -1.5 -1.8 -1.5 1.7 1.8 1.8 2.0 1.8 1.7 2.9 1.8
Medication: Co-codamol 0.3 0.3 1.6 0.1 -1.3 -0.3 -0.2 -0.1 -0.6 0.6 -0.1 -0.6 -0.6 -1.3 0.8 0.1 -0.1 -0.4 -0.3 0.5 -0.4 -0.2 0.7 0.5 0.6 0.1 0.0
Medication: Metformin 3.0 4.3 8.4 -1.9 -2.4 -2.3 -2.4 -2.2 -2.3 -2.9 -2.4 -2.5 0.3 -2.2 -0.3 -2.0 -1.2 -2.0 -2.2 2.1 2.0 1.9 2.2 2.0 1.9 1.6 2.1
Diabetes (father) 1.3 1.6 4.2 -1.2 -1.0 -0.6 -1.1 -1.1 -0.9 -1.7 -0.5 -1.6 1.4 -1.2 1.8 -2.0 -0.6 -0.9 -1.1 1.0 1.5 1.2 0.8 0.8 1.2 1.6 1.4
Diabetes (mother) 1.8 2.3 7.3 -2.0 -1.6 -1.3 -0.9 -1.2 -1.1 -1.5 -1.4 -1.0 1.7 -1.8 0.6 -2.4 -0.4 -1.4 -1.1 1.2 1.6 1.6 1.7 1.2 1.4 2.7 1.8
Severe depression (siblings) 0.2 0.3 2.1 -0.9 -0.8 0.1 0.2 0.1 -0.1 0.2 -0.1 -0.6 0.3 -0.9 -1.0 0.0 -1.5 0.2 0.2 -0.2 -0.3 0.1 0.2 -0.1 0.0 0.3 0.1
Pack years adult smoking proportion 0.7 1.1 2.6 -1.6 -1.6 -0.7 -0.9 -0.7 -0.6 -0.1 -0.9 -0.7 1.4 -1.6 1.4 -0.9 -1.4 -0.7 -0.8 0.7 0.9 1.4 1.1 0.7 0.8 1.0 1.1
Impedance of leg (right) 9.3 45.0 70.5 7.7 6.6 6.0 6.8 6.8 6.1 7.3 6.2 6.4 -5.5 6.8 0.5 8.4 5.9 6.6 7.0 -6.2 -8.0 -7.7 -6.6 -5.9 -6.6 -7.5 -8.1
Leg fat-free mass (left) 34.3 181.8 295.8 -16.0 -11.8 -12.3 -13.3 -13.7 -12.2 -14.0 -12.8 -12.6 12.4 -11.7 -2.0 -17.2 -9.4 -13.5 -14.2 12.4 17.1 16.3 13.1 11.7 13.3 15.3 17.1
Trunk fat percentage 0.1 0.5 1.9 -1.2 -0.7 0.0 1.0 0.0 0.1 0.3 0.3 -0.7 1.4 -0.9 1.3 -0.8 1.2 -0.2 -0.0 0.0 0.3 0.3 0.3 -0.1 0.3 0.9 0.6
Hand grip strength (right) 21.5 58.5 108.2 -8.9 -5.6 -6.8 -7.8 -8.0 -6.8 -7.3 -7.1 -6.1 7.0 -5.2 -3.2 -10.0 -4.8 -8.0 -8.0 7.3 10.4 9.6 7.2 7.0 8.0 8.9 10.1
Townsend deprivation index at recruitment 1.3 1.9 4.2 1.6 -0.5 1.0 0.6 1.4 1.1 1.4 1.3 0.6 -1.8 -0.5 0.4 2.0 -1.1 1.7 1.5 -1.3 -1.9 -1.3 -1.1 -1.3 -1.3 -2.0 -1.7
Current tobacco smoking 0.1 0.2 1.2 0.6 -0.4 0.3 -0.1 0.2 0.8 0.6 0.5 0.6 -1.1 -0.8 0.1 0.1 -0.3 0.2 0.3 -0.2 -0.1 0.4 -0.1 -0.1 -0.0 -0.0 -0.0
Average weekly fortified wine intake 0.3 0.4 3.0 0.4 0.3 0.2 -0.2 -0.4 0.5 -0.0 0.1 0.2 -0.5 0.5 -1.7 -0.5 0.4 -0.8 -0.6 0.6 0.9 0.8 0.2 0.6 0.7 0.5 0.6
Maternal smoking around birth 1.1 1.6 5.5 1.0 -0.3 0.9 0.9 1.1 0.6 1.4 0.9 -0.1 -2.3 -0.4 2.1 1.9 -1.2 1.1 0.8 -0.8 -1.7 -1.2 -0.7 -0.9 -1.1 -2.3 -1.5
Fed-up feelings 0.3 0.6 7.6 -1.0 -0.9 -0.7 0.4 -0.1 -0.6 -0.7 -0.6 -0.8 0.3 -1.3 2.8 0.4 0.6 0.2 -0.2 -0.1 -0.6 -0.3 0.3 -0.0 -0.2 -0.2 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 1.0 2.4 -1.4 -1.5 -1.3 -0.5 -0.9 -1.2 -0.5 -1.0 -1.4 0.7 -1.2 0.6 -0.9 -0.2 -0.9 -1.1 0.8 0.6 0.7 1.1 0.9 0.8 1.1 0.9
Relative age voice broke 6.2 9.5 20.2 2.9 2.5 2.9 2.8 3.2 2.9 3.0 2.9 2.0 -3.5 2.7 0.1 4.5 0.5 3.2 2.8 -3.0 -3.7 -3.5 -3.2 -2.9 -3.4 -4.5 -3.8
Taking other prescription medications 0.4 0.6 3.3 -0.5 -1.4 -0.4 -0.2 -0.3 -0.3 -0.3 -0.7 -0.3 -0.7 -1.8 1.4 -0.5 -1.6 -0.2 -0.3 0.3 -0.0 0.3 0.8 0.4 0.3 0.9 0.3
Age when periods started (menarche) 0.4 1.1 5.2 0.3 1.7 0.3 -0.3 0.2 0.9 0.2 -0.1 0.9 -1.3 1.8 -0.5 1.9 -1.3 0.5 -0.2 -0.3 -0.8 -0.6 -0.9 -0.1 -0.9 -2.3 -1.6
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.8 0.8 -0.6 0.2 0.1 0.5 0.9 -0.3 0.1 0.3 0.1 -0.2 0.1 0.5 -0.4 0.6 0.2 -0.6 -0.7 -0.3 -0.2 -0.4 -0.4 0.3 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 4.5 -1.7 0.5 0.2 1.1 0.3 -0.4 -0.5 0.3 -0.9 2.1 0.5 -0.7 0.0 1.6 0.2 0.1 -0.3 -0.6 -1.1 -0.5 -0.3 -0.4 0.0 -0.6
Tinnitus: Yes, but not now, but have in the past 1.3 1.3 2.2 0.6 1.2 1.3 1.1 1.4 1.3 1.5 1.3 1.1 0.2 1.4 0.1 1.0 0.7 1.4 1.2 -1.3 -0.9 -0.6 -1.4 -1.3 -1.4 -1.3 -1.3
Qualifications: CSEs or equivalent 6.1 8.0 12.5 3.5 2.5 3.1 2.5 3.2 3.1 3.0 3.2 2.9 -2.3 2.3 -1.6 2.7 2.0 3.1 3.2 -3.0 -2.9 -2.7 -3.0 -3.0 -2.9 -2.6 -2.9
Serious illness, injury or assault to yourself 0.6 0.7 1.7 0.3 -0.1 0.4 0.7 1.1 0.3 0.6 0.5 0.1 0.5 -0.1 -1.1 1.0 0.0 1.3 1.0 -1.2 -1.2 -1.1 -0.6 -1.2 -1.3 -0.8 -0.9
High blood pressure 0.5 1.4 5.0 -0.1 -2.2 -1.0 -0.1 -0.8 -1.5 -0.8 -1.0 -1.8 -0.0 -1.9 1.1 -1.2 -1.0 -1.1 -0.9 1.1 0.4 0.3 1.4 1.1 1.4 1.8 1.2
Hayfever, allergic rhinitis or eczema 0.2 0.3 1.3 -0.8 0.3 -0.7 -0.4 -0.5 -0.5 -0.6 -0.9 -0.0 1.1 0.6 0.2 -0.7 0.3 -0.5 -0.6 0.5 0.6 0.3 0.4 0.6 0.3 0.8 0.3
Multivitamins +/- minerals 1.2 1.6 3.9 -2.0 -1.2 -0.9 -0.8 -1.0 -0.7 -1.1 -1.2 0.0 0.5 -1.5 1.9 -1.4 -1.2 -1.2 -1.0 1.0 1.3 1.8 1.3 1.1 1.0 1.6 1.3
Stomach or abdominal pain in last month 0.9 1.1 2.2 0.4 0.3 1.0 1.1 1.5 0.8 0.9 1.1 0.2 -0.3 0.2 -0.1 1.3 0.4 1.4 1.2 -1.3 -1.4 -1.3 -1.0 -1.5 -1.4 -1.3 -1.2
Supplements: Glucosamine 0.2 0.3 4.5 -0.8 -0.1 -0.3 0.5 0.1 -0.2 0.4 -0.3 0.3 0.2 0.2 -2.1 0.4 0.3 -0.2 -0.0 0.2 -0.1 0.2 0.3 0.3 0.2 -0.0 -0.0
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 2.7 0.9 0.2 1.4 1.6 1.6 0.9 1.6 1.4 0.1 -0.6 -0.0 0.0 1.5 -0.1 1.5 1.3 -1.3 -1.6 -1.4 -1.1 -1.4 -1.2 -1.4 -1.2
Medication: Atenolol 1.2 1.5 3.7 -1.6 -0.6 -1.4 -1.1 -1.1 -1.1 -1.9 -1.2 -1.6 1.5 -0.7 1.5 -1.6 -0.4 -1.0 -1.3 0.9 0.9 0.8 1.0 1.0 1.0 1.6 0.9
Medication: Levothyroxine sodium 0.4 0.7 3.3 -0.9 -1.6 -0.4 -0.4 -0.5 -0.7 -0.5 -0.6 -0.5 -0.1 -1.8 0.3 -0.9 -1.7 -0.4 -0.4 0.4 0.9 1.1 0.8 0.2 0.4 0.9 1.2
Sitting height 56.2 399.2 681.2 -23.3 -15.8 -18.7 -19.9 -20.7 -18.3 -21.0 -19.9 -17.4 19.8 -14.8 -4.3 -25.4 -12.0 -20.2 -21.4 18.6 26.1 24.5 19.2 17.7 19.5 22.7 25.5
Chronic bronchitis/emphysema (father) 3.4 4.0 6.9 1.7 1.9 2.2 2.5 2.3 2.2 1.8 1.9 2.1 -0.6 1.7 0.9 1.6 1.2 2.5 2.3 -2.6 -2.0 -2.0 -2.2 -2.6 -2.5 -1.1 -1.9
High blood pressure (mother) 2.4 3.4 8.5 -1.1 -1.8 -1.5 -1.3 -1.7 -1.3 -1.5 -1.4 -1.4 2.9 -1.9 0.2 -2.1 -1.6 -2.0 -1.6 2.0 2.3 2.3 2.0 1.9 2.3 2.0 2.5
Body mass index (BMI) 0.2 0.8 4.3 -1.4 -1.7 -0.5 0.7 -0.1 -0.6 -0.9 -0.1 -1.7 1.2 -2.1 1.0 -0.5 0.3 -0.2 -0.2 0.2 -0.2 -0.1 0.6 0.2 0.4 0.7 0.3
Impedance of leg (left) 8.9 43.2 69.5 7.6 6.2 5.9 6.5 6.6 6.2 7.3 6.1 6.7 -5.3 6.3 0.2 8.3 5.4 6.5 7.0 -6.1 -8.0 -7.6 -6.3 -5.7 -6.4 -7.3 -8.1
Leg predicted mass (left) 34.1 180.9 295.8 -15.9 -11.8 -12.3 -13.2 -13.7 -12.1 -13.9 -12.8 -12.5 12.4 -11.6 -2.0 -17.2 -9.4 -13.4 -14.2 12.4 17.1 16.3 13.0 11.7 13.2 15.3 17.1
Trunk fat mass 5.1 21.9 38.1 -6.2 -4.7 -4.2 -3.6 -4.5 -4.0 -4.4 -4.1 -4.7 5.0 -4.7 0.3 -6.0 -2.4 -4.6 -4.8 4.2 5.7 5.5 4.6 3.9 4.6 5.5 6.0
Waist circumference 3.4 12.4 23.2 -4.8 -4.2 -3.5 -2.9 -3.5 -3.4 -3.6 -3.4 -4.2 2.8 -4.4 0.6 -4.1 -2.6 -3.3 -3.5 3.2 3.3 3.3 3.6 3.1 3.4 3.9 3.8
Number of incorrect matches in round 2.6 4.3 7.5 2.6 2.2 2.7 2.4 2.0 2.2 2.7 2.6 2.5 -1.8 2.4 -0.5 1.9 1.7 1.8 2.1 -1.9 -1.5 -1.5 -2.2 -1.9 -1.7 -2.0 -1.7
Past tobacco smoking 0.8 1.5 6.5 -2.6 -0.3 -0.8 -0.5 -1.0 -0.9 -1.7 -0.9 -1.3 2.1 -0.2 -0.1 -1.7 0.6 -1.1 -1.3 0.7 1.4 1.0 0.7 0.7 0.8 1.7 1.3
Alcohol usually taken with meals 8.3 13.5 19.3 -2.9 -2.6 -4.3 -3.7 -4.1 -4.2 -4.4 -4.2 -3.8 1.7 -2.4 -2.1 -3.8 -0.8 -4.2 -4.3 4.2 3.8 3.5 3.9 4.3 4.2 3.8 3.8
Nervous feelings 0.3 0.6 2.7 -1.7 -0.9 -0.7 -0.6 -0.6 -0.7 0.4 -0.7 -0.5 -1.1 -0.9 -1.2 0.7 -1.2 -0.3 -0.5 0.6 -0.4 0.1 0.6 0.7 0.3 -0.9 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.7 -1.2 -1.3 -0.8 -0.5 -0.2 -1.6 0.1 -0.4 -1.6 -1.1 -1.6 -0.4 -0.1 -0.3 -0.0 -0.2 0.3 -0.4 -0.2 0.6 0.1 0.2 -0.1 0.1
Hearing difficulty/problems with background noise 0.1 0.2 1.4 -0.6 -0.0 -0.6 -0.6 -0.4 -0.2 0.3 -0.8 0.1 -0.5 0.1 -0.3 0.2 -1.2 -0.4 -0.4 0.4 0.3 0.6 0.4 0.5 0.3 -0.1 0.2
Hair/balding pattern: Pattern 2 0.9 1.1 2.9 0.5 0.4 0.8 1.0 0.8 1.4 1.6 1.2 1.0 -0.9 0.3 -1.5 1.7 1.1 0.7 0.7 -0.7 -1.3 -1.0 -0.9 -0.6 -0.6 -1.5 -1.2
Had menopause 2.0 2.6 5.2 -2.3 -1.9 -1.7 -1.1 -1.7 -1.0 -1.3 -1.7 -0.2 1.4 -1.8 -0.8 -1.5 -1.5 -1.6 -1.5 1.4 1.7 2.2 1.8 1.5 1.6 2.0 1.8
Had other major operations 0.2 0.2 2.1 -0.5 -0.2 0.2 0.4 0.2 0.6 0.5 0.5 0.3 0.3 -0.1 1.4 0.2 0.1 0.2 0.0 -0.4 -0.6 -0.4 -0.2 -0.3 -0.3 0.0 -0.5
Forced vital capacity (FVC) 4.3 16.4 28.0 -4.3 -3.7 -3.6 -4.4 -4.4 -3.7 -3.0 -4.0 -3.6 1.4 -3.6 -1.6 -5.0 -3.8 -4.2 -4.5 3.9 5.1 4.9 4.1 3.8 4.3 4.7 5.3
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 5.8 -2.0 -0.1 -0.0 0.4 0.1 -0.4 -0.8 0.1 -1.0 2.4 0.0 -2.1 -0.5 1.1 -0.0 -0.2 -0.1 -0.0 -0.5 -0.2 -0.1 -0.1 0.6 -0.0
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 2.7 -1.1 -0.9 -0.4 -0.7 -0.2 0.1 -0.0 -0.2 -0.0 1.7 -1.4 0.9 -0.9 -0.3 -0.3 -0.2 0.3 0.9 0.9 0.6 0.2 0.5 0.8 1.1
Qualifications: None of the above 3.8 8.1 13.5 3.5 2.0 2.9 3.0 2.9 3.4 3.1 3.0 3.5 -2.2 1.7 1.1 3.7 1.7 2.8 3.1 -2.7 -3.4 -2.5 -2.7 -2.6 -2.7 -3.3 -3.3
Financial difficulties in last 2 years 0.3 0.4 2.5 -0.7 -1.2 -0.8 -0.4 0.0 -1.0 -0.6 -0.6 -0.7 -0.7 -1.2 1.6 -0.2 0.2 0.1 0.1 -0.1 -0.1 0.0 0.5 -0.2 -0.2 0.2 0.3
Mouth/teeth dental problems 2.9 4.4 7.2 -2.0 -2.2 -2.1 -2.2 -2.1 -2.2 -2.4 -2.3 -2.6 -0.5 -1.9 -0.2 -1.8 -2.7 -2.1 -2.2 2.3 2.1 2.3 2.2 2.3 2.2 1.4 2.0
Heart attack 0.3 0.4 4.7 -0.7 -0.8 -0.3 0.7 0.1 0.1 0.3 -0.1 -0.1 0.7 -0.6 2.2 -0.2 -0.5 -0.1 0.1 -0.0 -0.4 -0.1 0.3 0.2 0.2 0.8 -0.1
Allergy 0.7 1.5 3.9 2.0 0.9 1.2 1.2 1.3 0.9 1.3 1.5 1.0 -0.7 1.1 0.5 1.3 1.7 1.1 1.5 -1.2 -1.4 -1.1 -1.2 -1.3 -1.1 -1.2 -1.2
Pain all over the body in last month 0.3 0.3 0.9 -0.5 -0.0 0.1 0.2 0.7 0.4 0.4 0.2 0.4 0.3 0.1 0.8 0.1 0.5 0.8 0.6 -1.0 -0.5 -0.3 -0.4 -0.9 -0.9 0.2 -0.4
Diabetes (self-reported) 2.5 3.9 7.0 -2.3 -2.0 -2.4 -2.0 -2.0 -2.5 -2.6 -2.4 -2.6 0.6 -1.8 0.1 -2.1 -0.8 -1.8 -2.2 1.9 2.0 1.6 2.1 1.7 1.7 1.8 2.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.2 -1.0 -0.2 -0.3 -0.2 -0.3 0.3 -1.0 -0.6 -0.1 1.5 -0.5 -0.0 -0.7 -1.2 -0.1 -0.5 0.0 0.2 0.3 0.3 0.2 0.0 1.0 0.1
Medication: Ramipril 1.0 1.2 6.9 -0.9 -0.6 -1.4 -0.9 -1.1 -1.2 -1.4 -1.4 -1.5 -0.0 -0.2 2.6 -1.1 0.1 -1.0 -1.2 0.9 0.8 0.5 0.9 0.9 0.8 1.1 0.8
Medication: Simvastatin 1.1 1.6 7.0 1.8 2.2 1.1 1.2 0.7 1.3 1.1 1.0 1.5 -0.1 2.6 1.4 0.2 2.2 0.5 0.8 -0.7 -0.6 -1.1 -1.2 -0.6 -0.6 0.1 -1.0
Fluid intelligence score 5.2 10.8 18.2 -4.3 -3.1 -3.7 -2.6 -3.5 -3.5 -3.6 -3.5 -3.5 3.6 -3.0 -0.3 -3.1 -1.3 -3.5 -3.7 3.5 3.5 3.0 3.5 3.3 3.4 2.8 3.7
Illnesses of siblings 1.6 2.2 7.2 1.3 2.7 1.5 0.6 1.0 2.1 1.1 1.5 2.2 0.6 2.4 1.2 0.9 1.9 1.2 1.0 -1.4 -0.6 -0.8 -1.8 -1.3 -1.5 -1.2 -1.3
Neuroticism score 0.5 1.0 3.5 -1.9 -1.8 -1.3 -0.9 -0.6 -1.3 -0.7 -1.2 -1.8 -0.0 -1.8 0.6 -0.2 -0.9 -0.4 -1.0 0.6 -0.0 0.3 1.0 0.6 0.5 0.2 0.3
Weight 19.3 95.1 152.2 -11.9 -9.1 -9.0 -8.9 -9.8 -8.8 -10.1 -9.3 -9.4 9.5 -9.0 -1.0 -12.3 -6.1 -9.6 -10.2 8.9 12.1 11.6 9.6 8.4 9.6 11.2 12.3
Impedance of arm (right) 4.5 21.0 36.0 5.5 5.4 4.7 4.0 4.6 4.6 6.0 4.7 5.2 -3.1 5.8 0.7 4.2 4.7 4.3 4.8 -4.5 -4.2 -4.4 -4.8 -4.4 -4.5 -3.7 -4.6
Arm fat percentage (right) 0.7 2.6 7.1 0.5 0.2 1.5 2.7 1.9 1.3 1.6 1.8 0.4 -0.4 0.1 1.5 1.6 2.0 1.8 1.8 -1.7 -2.4 -2.2 -1.3 -1.7 -1.7 -1.1 -1.9
Trunk fat-free mass 44.9 257.9 408.0 -18.9 -14.1 -15.1 -16.2 -16.5 -14.6 -16.9 -15.9 -14.6 14.3 -13.7 -3.4 -19.9 -11.8 -16.0 -17.1 14.9 20.2 19.3 15.7 14.2 15.7 17.8 20.1
Hip circumference 12.0 51.8 85.2 -8.6 -6.9 -6.8 -6.3 -7.1 -6.6 -7.4 -6.7 -6.9 7.5 -6.9 -1.3 -9.2 -3.8 -7.1 -7.1 6.6 8.9 8.5 7.1 6.2 7.2 8.4 9.2
Time employed in main current job 0.9 1.0 5.4 1.5 1.7 0.6 0.8 0.8 0.3 0.9 0.6 1.2 0.4 2.0 -0.8 0.3 2.3 0.6 1.0 -0.8 -0.2 -0.4 -0.8 -0.8 -0.7 -0.1 -0.3
Alcohol intake versus 10 years previously 4.5 6.8 12.1 -2.7 -3.5 -2.6 -3.0 -2.6 -2.5 -2.6 -2.7 -1.9 0.4 -3.5 1.4 -2.8 -2.8 -2.4 -2.5 2.5 2.3 2.9 3.0 2.5 2.5 2.7 2.5
Father’s age at death 0.7 0.9 1.9 0.2 -0.7 -1.0 -1.2 -0.8 -1.3 -1.1 -1.1 -0.5 -1.3 -0.6 0.0 -0.7 -1.4 -0.9 -0.6 1.2 1.2 1.2 1.1 1.1 1.0 0.4 1.1
Worrier / anxious feelings 0.7 1.3 3.2 -1.8 -1.6 -1.4 -1.2 -1.0 -1.1 -0.8 -1.6 -0.9 -0.7 -1.4 0.8 -0.6 -1.6 -0.9 -1.2 1.0 0.6 0.9 1.3 1.2 0.9 0.8 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 6.9 -2.6 -1.3 -1.0 -0.1 -0.5 -1.6 -0.8 -0.8 -1.6 1.4 -1.6 0.4 -0.7 0.2 -0.4 -0.7 0.2 0.3 0.2 0.7 0.1 0.2 0.9 0.7
Falls in the last year 0.2 0.2 1.1 0.0 -0.0 0.1 0.5 0.6 -0.3 -0.1 -0.0 -0.4 -1.0 0.0 0.2 0.6 0.0 0.6 0.3 -0.7 -0.7 -0.6 -0.3 -0.7 -0.8 -0.5 -0.5
Hair/balding pattern: Pattern 3 1.6 2.4 5.7 -1.6 -0.8 -1.3 -0.7 -1.5 -1.5 -1.7 -1.6 -0.8 2.4 -0.7 -0.0 -2.2 -1.2 -1.5 -1.4 1.4 2.2 1.7 1.5 1.2 1.4 2.1 2.2
Number of live births 1.8 2.5 4.6 1.9 0.8 2.0 1.4 1.8 1.8 1.8 2.2 2.0 -0.6 1.2 -0.6 1.2 1.3 1.8 2.0 -1.8 -1.6 -1.0 -1.7 -1.9 -1.6 -1.2 -1.5
Forced expiratory volume in 1-second (FEV1) 4.6 15.6 25.5 -4.6 -3.7 -3.8 -4.1 -4.3 -4.0 -3.0 -4.1 -3.9 0.9 -3.6 -0.9 -4.3 -3.8 -4.1 -4.5 3.9 4.8 4.6 4.1 3.7 4.1 3.8 5.0
Pulse rate 3.5 6.0 10.6 2.7 1.4 2.6 1.7 2.7 3.1 3.3 2.4 2.8 -1.8 0.7 1.0 2.9 -0.2 2.8 2.9 -2.6 -3.0 -2.5 -2.3 -2.5 -2.6 -2.4 -2.8
Happiness 1.0 1.3 5.1 -1.2 -1.0 -1.5 -1.0 -1.1 -1.3 -1.1 -1.3 -0.5 1.3 -1.0 2.3 -1.0 1.3 -0.9 -1.0 0.9 0.7 0.8 1.1 1.0 0.8 1.2 0.7
Noisy workplace 1.5 1.8 3.7 0.8 0.7 1.8 1.3 1.5 1.5 1.9 1.8 1.6 -1.6 0.4 0.2 1.4 -0.4 1.4 1.6 -1.4 -1.3 -1.0 -1.4 -1.4 -1.3 -1.4 -1.2
Qualifications: A levels/AS levels or equivalent 4.2 9.2 18.0 -3.5 -1.9 -2.8 -2.7 -3.1 -3.0 -2.9 -2.8 -2.9 4.2 -1.8 -1.6 -3.9 -1.2 -3.2 -3.2 2.8 3.9 3.5 2.8 2.7 3.0 3.4 3.9
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 3.1 -0.0 -1.0 -1.6 -1.3 -1.4 -1.1 -1.1 -1.6 -0.7 0.8 -0.8 0.3 -0.8 -0.5 -1.7 -1.3 1.7 1.4 1.4 1.6 1.8 1.6 0.9 1.3
Mouth/teeth dental problems: Dentures 0.2 0.3 2.3 0.3 0.4 0.4 -0.0 0.3 0.7 0.3 0.3 1.4 1.5 0.3 0.8 -0.4 0.2 0.4 0.4 -0.5 0.3 0.4 -0.3 -0.5 -0.5 0.4 0.2
Asthma 2.9 5.7 8.7 -2.5 -2.7 -2.5 -2.4 -2.6 -2.0 -2.2 -2.6 -2.1 0.6 -2.9 -1.2 -2.5 -2.7 -2.4 -2.6 2.5 2.0 1.8 2.7 2.6 2.6 2.7 2.3
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 2.0 0.3 0.6 -0.8 -0.3 -0.2 -0.6 -0.3 -0.8 0.1 0.3 0.8 -0.8 -0.1 1.4 -0.3 -0.2 0.3 0.3 0.1 0.3 0.4 0.1 0.3 0.1
Medication: Cholesterol lowering 1.3 2.0 4.6 1.6 1.9 1.4 1.5 1.5 1.2 1.6 1.5 1.3 0.1 2.1 0.8 0.9 1.7 1.3 1.5 -1.5 -1.2 -1.3 -1.6 -1.5 -1.5 -1.0 -1.3
Depression (self-reported) 0.2 0.2 1.2 1.1 0.2 -0.0 -0.2 0.2 0.7 0.2 0.4 0.5 0.3 -0.0 -0.6 -0.0 1.0 0.1 0.2 -0.2 -0.5 -0.3 -0.2 -0.1 -0.0 0.3 -0.5
Medication: Lansoprazole 5.4 6.1 10.2 1.7 1.7 2.5 2.9 2.5 2.1 2.9 2.6 1.6 -2.5 1.8 1.5 3.0 0.1 2.6 2.4 -2.5 -3.2 -3.1 -2.5 -2.5 -2.7 -2.8 -3.1
Prospective memory result 4.1 5.1 9.0 1.2 2.0 2.5 2.2 2.5 2.3 2.2 2.2 2.3 -0.6 1.5 2.4 2.2 -0.1 2.9 2.7 -2.8 -2.2 -2.0 -2.6 -2.8 -3.0 -2.1 -2.4
Lung cancer (father) 0.5 0.5 3.9 -0.3 -0.0 0.8 0.1 0.5 1.0 0.7 0.6 0.6 1.5 -0.3 0.4 -0.7 -2.0 0.5 0.6 -0.6 0.4 0.6 -0.4 -0.7 -0.3 0.8 0.3
Illnesses of mother 0.7 0.9 3.2 -1.3 -1.2 -0.9 -1.7 -0.8 -0.9 -1.3 -1.1 -1.1 -0.8 -1.3 0.4 -0.6 -1.8 -0.4 -1.0 0.5 0.5 0.6 0.8 0.5 0.4 0.4 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 4.4 14.1 24.4 -4.4 -3.4 -3.4 -3.9 -4.2 -3.4 -2.7 -3.7 -3.3 1.7 -3.3 -0.6 -4.0 -3.5 -4.0 -4.4 3.8 4.9 4.9 3.8 3.6 4.0 3.3 4.9
Pulse wave Arterial Stiffness index 0.4 0.5 2.4 -1.2 -0.3 -0.5 -0.0 -0.3 -0.0 -0.8 -0.6 -0.1 1.5 -0.5 1.4 -0.9 -0.0 -0.3 -0.4 0.3 0.7 0.8 0.4 0.3 0.3 0.9 0.6
Impedance of arm (left) 3.8 17.7 32.2 5.1 5.0 4.4 3.7 4.0 4.4 5.7 4.4 4.8 -3.0 5.3 0.8 4.1 4.2 3.8 4.2 -3.9 -3.7 -3.9 -4.4 -3.9 -3.9 -3.9 -4.2
Arm fat mass (right) 2.5 10.5 22.3 -4.7 -3.7 -2.9 -2.1 -2.8 -2.9 -3.4 -2.8 -3.7 3.9 -3.8 0.4 -4.1 -1.2 -2.8 -3.1 2.6 3.5 3.5 3.2 2.4 2.9 4.0 4.0
Trunk predicted mass 45.3 259.0 408.0 -18.9 -14.1 -15.2 -16.2 -16.6 -14.6 -17.0 -15.9 -14.7 14.3 -13.7 -3.4 -19.9 -11.8 -16.1 -17.2 15.0 20.2 19.3 15.7 14.3 15.8 17.8 20.1
Standing height 45.6 452.8 788.9 -24.3 -17.2 -19.7 -21.9 -22.1 -18.7 -21.0 -21.0 -17.9 19.5 -16.3 -4.4 -27.0 -14.7 -21.7 -22.8 19.9 28.1 26.7 20.6 18.9 21.1 24.1 27.5
Length of working week for main job 2.8 3.1 5.7 -2.1 -1.7 -1.8 -1.9 -2.0 -1.8 -2.4 -1.6 -2.3 1.4 -1.7 0.1 -1.9 -1.1 -1.7 -2.3 1.8 1.8 1.7 1.6 1.7 1.7 1.4 1.6
Exposure to tobacco smoke at home 0.3 0.4 1.4 0.0 -0.4 -0.1 0.2 0.4 -0.3 0.4 -0.2 -0.0 -1.2 -0.6 1.1 0.7 -0.7 0.6 0.5 -0.4 -1.2 -0.8 -0.0 -0.2 -0.7 -0.5 -1.0
Breastfed as a baby 0.1 0.2 0.9 0.2 -0.2 -0.3 -0.5 -0.5 0.0 0.2 -0.3 0.5 -0.4 -0.1 0.7 0.1 -1.0 -0.4 -0.5 0.3 -0.3 -0.0 0.2 0.6 0.3 0.3 -0.4
Tense / ‘highly strung’ 0.6 1.0 2.6 -1.4 -1.6 -1.3 -1.3 -1.0 -1.2 -0.3 -1.2 -1.0 0.3 -1.4 -0.0 -0.7 -0.6 -1.0 -1.0 1.0 0.4 1.0 1.2 1.1 0.9 0.8 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 6.9 -1.8 -1.3 -1.3 -0.8 -0.8 -1.0 -0.9 -1.1 -1.3 2.6 -1.4 -0.4 -1.0 0.4 -0.7 -1.0 0.6 0.6 0.4 0.9 0.6 0.6 1.2 0.8
Hair/balding pattern: Pattern 4 0.5 1.2 4.8 -0.7 1.9 1.1 1.3 1.1 0.3 0.9 0.9 0.6 -0.0 2.2 0.5 0.5 1.2 1.1 1.3 -1.1 -0.8 -1.5 -1.2 -1.2 -1.2 -0.5 -1.0
Birth weight of first child 0.4 0.8 2.9 1.1 1.2 1.1 1.0 0.7 1.2 1.7 1.1 1.1 0.6 1.4 -1.1 -0.0 1.0 0.4 0.6 -0.7 0.3 0.1 -0.9 -0.8 -0.4 0.1 0.2
Peak expiratory flow (PEF) 12.6 29.3 51.9 -6.3 -4.2 -5.2 -5.5 -5.8 -4.9 -4.5 -5.4 -4.2 4.6 -4.0 -1.9 -6.7 -3.5 -5.8 -5.9 5.3 7.2 6.7 5.5 5.0 5.6 6.2 7.2
Pulse wave reflection index 1.4 1.8 3.4 -1.7 -1.0 -1.1 -0.5 -1.3 -1.6 -1.8 -1.2 -1.5 1.1 -0.8 1.8 -1.7 -0.8 -1.2 -1.3 1.3 1.5 1.4 1.2 1.2 1.3 1.2 1.4
Ever highly irritable/argumentative for 2 days 0.2 0.3 2.8 0.0 -0.3 0.2 0.2 0.2 0.2 0.8 0.2 -0.4 -0.7 -0.1 1.7 0.4 -0.6 0.3 0.2 -0.2 -0.0 -0.0 -0.2 -0.3 -0.3 -0.9 0.1
Loud music exposure frequency 1.6 1.8 4.4 0.5 0.9 1.6 1.3 1.3 1.9 2.1 1.7 1.7 -0.6 1.1 0.4 0.8 0.9 1.3 1.2 -1.6 -1.6 -1.2 -1.5 -1.4 -1.3 -0.2 -1.7
Qualifications: O levels/GCSEs or equivalent 3.9 6.2 12.0 -2.9 -2.3 -2.3 -2.7 -2.2 -2.0 -2.6 -2.1 -2.8 2.3 -2.5 -2.1 -3.5 -2.2 -2.1 -2.4 2.0 2.6 2.5 2.2 1.9 2.3 3.4 2.7
Mouth/teeth dental problems: Bleeding gums 1.3 1.7 3.7 1.5 1.0 1.3 1.7 1.5 1.0 1.5 1.6 0.3 -0.3 0.7 -0.5 1.3 1.9 1.2 1.2 -1.4 -1.8 -1.9 -1.3 -1.4 -1.2 -1.0 -1.5
Blood clot in the leg (DVT) 1.7 2.2 11.4 -2.1 -1.6 -0.5 -1.1 -1.2 -0.2 -1.5 -1.2 -1.2 -0.0 -1.8 -0.0 -1.2 -3.4 -1.1 -2.0 1.1 1.8 2.0 1.2 1.0 1.1 0.8 1.7
Medication: Paracetamol 0.3 0.4 3.5 -0.2 -0.6 -0.7 0.1 -0.4 -0.5 -0.6 -0.5 -0.8 -0.8 -0.8 1.9 -0.1 0.2 -0.6 -0.7 0.6 -0.0 0.4 0.7 0.8 0.7 0.3 0.1
Headache pain in last month 1.5 2.6 5.0 -1.2 -1.2 -1.9 -1.8 -1.9 -2.2 -1.8 -1.9 -2.1 0.3 -1.4 1.4 -0.8 -1.5 -1.8 -2.1 2.0 1.5 1.3 1.7 1.9 1.7 0.4 1.4
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 3.0 -1.2 -0.8 -1.0 -1.1 -0.8 -0.3 -0.9 -1.0 0.0 0.2 -1.0 -1.7 -0.3 -0.5 -0.6 -0.8 0.7 0.6 0.9 0.9 0.8 0.6 0.6 0.5
Glaucoma (self-reported) 0.3 0.3 3.7 0.7 0.4 0.1 -0.5 0.0 -0.3 -0.1 0.1 -0.1 -0.5 0.5 -1.9 0.5 1.0 -0.1 0.1 0.2 0.2 0.2 -0.2 0.0 0.0 -1.1 -0.0
Gout (self-reported) 0.4 0.5 1.5 0.4 0.7 0.7 0.9 0.6 0.9 0.8 0.6 0.8 -0.8 0.8 -1.2 0.8 0.4 0.5 0.4 -0.5 -0.6 -0.5 -0.6 -0.5 -0.6 -0.9 -0.7
Hypothyroidism/myxoedema (self-reported) 0.7 1.3 6.9 -1.1 -2.3 -0.6 -0.9 -0.5 -1.0 -1.0 -0.7 -0.7 0.1 -2.6 0.3 -1.1 -2.0 -0.3 -0.4 0.4 0.9 1.4 1.1 0.2 0.5 1.2 1.3
Medication: Amlodipine 0.2 0.3 3.7 0.9 -0.3 0.2 -0.1 -0.2 0.5 0.1 0.2 0.0 -1.9 -0.0 -0.2 -0.5 -0.1 -0.3 -0.3 0.1 0.0 -0.1 0.1 0.2 0.3 1.0 0.1
Medication: Ventolin 100micrograms inhaler 2.1 2.7 6.4 -2.2 -1.9 -1.5 -1.4 -2.0 -1.6 -1.4 -1.5 -1.2 -0.3 -2.3 0.1 -2.0 -2.3 -1.5 -1.8 1.5 1.1 0.8 1.6 1.7 1.6 2.5 1.3
Birth weight 1.0 2.1 7.1 -1.2 -1.1 -0.4 -0.8 -1.3 -0.7 -0.2 -0.9 -1.0 1.6 -0.9 0.9 -2.0 -2.6 -1.2 -1.4 1.0 2.6 2.2 1.1 0.7 1.2 1.5 2.7
Chronic bronchitis/emphysema (mother) 2.1 2.5 7.8 1.6 1.5 1.3 1.4 1.1 1.2 2.1 1.3 2.0 -0.7 1.5 2.8 2.1 1.2 1.3 1.6 -1.1 -1.5 -1.3 -1.4 -1.1 -1.2 -2.3 -1.6
High blood pressure (siblings) 2.6 3.7 7.9 -1.7 -2.7 -2.3 -1.2 -1.8 -2.8 -2.2 -2.4 -2.5 0.4 -2.6 -0.7 -1.2 -1.9 -1.7 -1.5 2.0 1.3 1.3 2.4 1.9 2.0 1.1 1.9
Forced vital capacity (FVC), Best measure 4.8 17.7 31.9 -4.5 -3.8 -3.6 -4.5 -4.5 -3.6 -3.0 -4.0 -3.5 2.4 -3.6 -1.3 -5.0 -3.8 -4.4 -4.7 4.1 5.6 5.5 4.2 4.0 4.5 4.5 5.7
Body fat percentage 0.5 1.9 6.1 0.5 0.3 1.3 2.5 1.6 1.3 1.5 1.6 0.5 0.0 0.1 1.3 1.4 2.1 1.4 1.5 -1.3 -1.8 -1.7 -1.1 -1.4 -1.3 -1.1 -1.4
Leg fat percentage (right) 3.4 12.3 26.3 2.9 1.9 3.0 4.9 3.9 2.8 3.1 3.4 1.9 -2.1 1.7 1.2 4.6 3.6 3.7 3.9 -3.4 -5.1 -4.8 -3.1 -3.3 -3.6 -3.9 -4.6
Arm fat-free mass (right) 39.2 201.1 306.2 -16.9 -12.9 -13.4 -14.1 -14.6 -12.8 -15.1 -14.0 -13.2 12.6 -12.8 -2.7 -17.1 -10.7 -14.1 -15.1 13.3 17.4 16.9 14.0 12.7 14.0 15.2 17.5
Exposure to tobacco smoke outside home 1.0 1.4 3.9 -1.1 -1.8 -1.4 -1.1 -1.1 -1.6 -0.8 -1.3 -1.0 0.2 -2.0 1.2 -1.1 -1.4 -0.9 -0.9 1.0 0.7 1.0 1.5 1.0 1.0 1.1 1.0
Comparative body size at age 10 0.4 1.1 2.7 0.6 0.3 1.3 1.7 1.1 0.7 1.4 1.4 0.2 -0.4 -0.0 -0.7 1.3 1.2 1.1 1.3 -1.0 -1.2 -1.2 -1.0 -1.1 -0.9 -1.4 -0.9
Number of full brothers 0.6 0.7 2.9 0.1 0.7 1.2 0.2 0.6 1.2 1.0 0.9 1.0 -1.7 0.6 -0.6 0.9 -0.3 0.9 0.6 -0.8 -0.5 -0.2 -1.0 -0.8 -0.8 -1.3 -0.7
Worry too long after embarrassment 0.1 0.3 1.3 -0.9 -0.4 -0.6 -0.6 -0.4 -0.6 0.0 -0.5 -1.1 0.3 -0.0 -0.6 -0.2 0.2 -0.4 -0.7 0.5 0.2 0.2 0.3 0.5 0.5 -0.1 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.2 -0.9 -0.8 -0.9 -0.9 -0.5 -1.1 -1.0 -0.8 -1.1 -0.8 -0.8 -0.6 -0.8 0.3 -0.3 -0.7 0.2 0.3 0.1 0.6 0.2 0.2 1.0 0.5
Wheeze or whistling in the chest in last year 2.2 3.9 7.8 -2.1 -2.5 -2.1 -2.0 -2.1 -1.9 -2.1 -2.1 -1.4 0.4 -2.5 0.9 -2.1 -2.8 -1.9 -2.1 1.8 1.5 1.7 2.2 2.0 1.9 2.3 1.6
Number of children fathered 0.2 0.3 1.1 0.2 0.6 0.0 0.1 -0.5 0.0 0.2 0.1 -0.1 0.6 1.1 -0.4 -0.5 1.0 -0.8 -0.5 0.6 0.8 0.3 0.1 0.5 0.6 0.3 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.4 3.2 -0.5 -0.6 0.6 0.7 -0.0 0.8 0.7 0.5 0.7 1.8 -0.6 -0.3 -0.3 -1.6 -0.2 0.0 -0.1 0.1 0.1 0.0 -0.1 0.3 0.9 0.3
Age at first live birth 0.8 1.4 4.2 -1.1 -0.4 -1.2 -1.1 -1.3 -1.5 -1.2 -1.2 -1.2 2.0 -0.3 -1.5 -1.2 -0.4 -1.3 -1.2 1.2 1.4 0.9 1.0 1.2 1.2 1.1 1.2
Pulse wave peak to peak time 0.6 0.7 2.6 -0.3 -0.6 -0.6 -1.1 -1.0 -1.0 -0.4 -0.6 -0.9 -0.1 -0.4 -1.6 -0.9 -0.6 -1.0 -0.9 0.9 1.0 0.8 0.7 0.8 1.0 0.7 1.1
Health satisfaction 0.8 1.1 16.1 -1.5 -1.3 -0.7 0.3 -0.2 -0.6 -0.6 -0.9 -0.9 0.4 -1.4 4.0 0.0 -0.6 -0.0 -0.3 0.2 0.0 0.2 0.7 0.2 0.0 -0.0 0.4
Shortness of breath walking on level ground 0.7 0.8 7.1 -0.4 -2.0 -0.2 -0.0 0.5 -0.2 -0.4 -0.2 -1.1 0.2 -2.1 2.7 -0.1 -1.4 0.5 0.2 -0.3 -0.5 0.3 0.4 -0.3 -0.3 0.2 -0.0
Qualifications: College or University degree 3.2 10.2 17.0 -4.1 -1.8 -2.9 -3.4 -3.6 -3.3 -3.7 -3.2 -3.2 3.7 -1.5 -1.6 -3.7 -1.6 -3.4 -3.7 3.2 4.1 3.4 2.7 3.1 3.1 3.1 3.7
Eye problems/disorders: None of the above 0.1 0.1 0.6 -0.3 0.2 0.1 -0.5 -0.2 0.8 -0.2 0.1 0.2 0.5 0.2 0.2 -0.4 0.1 -0.3 -0.4 0.1 0.6 0.6 -0.1 0.1 0.1 0.3 0.3
Mouth/teeth dental problems: Loose teeth 0.3 0.4 3.5 -0.5 -0.4 -0.1 -0.1 -0.3 0.4 -0.3 -0.1 0.6 1.9 -0.4 -0.5 -0.7 0.1 -0.5 -0.1 0.4 0.9 0.9 0.4 0.3 0.5 0.9 1.0
Emphysema/chronic bronchitis 0.7 0.8 4.3 0.8 -0.1 0.6 0.4 1.0 0.5 0.6 0.5 0.2 -2.1 0.2 0.3 1.0 -0.7 1.2 0.9 -0.9 -1.2 -0.8 -0.6 -0.8 -1.0 -1.0 -1.0
Medication for pain relief, constipation, heartburn 0.2 0.4 2.8 -0.5 -0.2 0.1 -0.6 -0.7 0.0 -0.2 -0.1 0.0 0.6 -0.2 -1.2 -0.7 -1.7 -0.5 -0.3 0.5 0.9 0.7 0.2 0.4 0.6 0.5 0.8
Neck or shoulder pain in last month 0.2 0.3 2.4 -1.0 -0.1 -0.3 0.5 0.4 -0.7 -0.1 -0.4 0.5 1.6 -0.1 -0.2 -0.3 0.1 0.5 0.7 -0.6 -0.1 0.0 0.1 -0.6 -0.7 0.6 0.0
Medication: Blood pressure 0.5 0.9 4.1 0.2 -1.0 -0.7 -0.0 -0.8 -1.5 -0.7 -0.7 -1.4 0.4 -0.8 2.0 -1.2 -0.5 -0.9 -0.6 0.9 0.6 0.3 0.9 0.8 1.1 1.2 1.0
Angina (self-reported) 0.7 0.9 3.0 -1.5 -1.5 -1.3 -0.6 -0.6 -0.9 -1.2 -1.2 -0.7 0.9 -1.2 1.7 -0.8 -0.0 -0.6 -0.7 0.6 0.3 0.5 1.1 0.7 0.5 1.1 0.6
Migraine (self-reported) 4.4 5.4 10.9 -1.5 -3.3 -2.7 -2.6 -2.4 -2.5 -2.6 -2.5 -2.5 0.0 -3.3 -0.8 -1.6 -1.7 -2.4 -2.6 2.6 1.7 1.9 2.8 2.7 2.6 1.7 2.0
Medication: Ibuprofen 0.3 0.4 0.9 -0.1 0.1 -0.9 -0.6 -0.5 -0.8 -0.5 -0.9 -0.3 0.6 0.3 -1.0 -0.7 0.8 -0.7 -0.6 0.6 0.5 0.5 0.6 0.8 0.5 0.9 0.4
Medication: Allopurinol 0.4 0.6 1.3 0.4 0.8 0.9 1.1 0.6 0.7 1.1 0.9 0.6 -0.9 0.9 -0.8 0.8 0.7 0.6 0.5 -0.6 -0.8 -0.7 -0.8 -0.5 -0.5 -0.9 -0.9
Medication: Omeprazole 0.1 0.2 2.1 0.6 0.2 0.1 0.3 -0.2 -0.1 0.4 0.1 0.0 0.1 0.3 1.4 0.0 0.1 -0.4 -0.2 0.5 0.0 -0.3 0.1 0.5 0.5 0.1 0.0
Medication: Seretide 50 evohaler 1.3 1.5 3.6 -0.7 -1.4 -1.2 -1.3 -1.3 -0.6 -1.1 -1.3 -0.5 0.3 -1.7 0.7 -1.3 -1.9 -1.3 -1.2 1.4 0.9 0.8 1.4 1.5 1.4 1.9 1.0
Mean time to correctly identify matches 3.9 7.4 12.5 3.5 2.8 3.2 3.0 3.0 3.1 2.7 3.3 2.6 -0.6 2.9 1.3 1.9 3.4 2.6 2.8 -2.8 -2.5 -2.6 -3.0 -2.8 -2.5 -1.5 -2.6
Heart disease (mother) 0.4 0.5 2.0 -0.1 0.6 0.4 1.1 0.7 -0.1 0.8 0.5 -0.3 -0.4 0.7 0.3 0.3 1.4 0.7 0.8 -0.7 -0.7 -1.0 -0.6 -0.8 -0.7 -0.3 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 2.0 3.7 1.1 1.6 1.4 1.2 1.6 1.4 1.0 1.2 1.6 0.1 1.5 -0.6 1.1 1.3 1.8 1.5 -1.9 -1.5 -1.3 -1.7 -1.9 -1.8 -0.7 -1.5
Whole body fat mass 3.6 14.8 27.6 -5.3 -4.1 -3.5 -2.8 -3.6 -3.3 -3.9 -3.4 -4.1 4.4 -4.1 0.1 -4.8 -1.6 -3.7 -3.9 3.4 4.5 4.4 3.8 3.2 3.7 4.5 4.8
Leg fat mass (right) 1.1 4.1 10.2 -3.2 -2.6 -1.9 -0.7 -1.6 -1.9 -2.4 -1.7 -2.9 2.7 -2.7 0.3 -2.3 -0.3 -1.6 -1.8 1.5 1.9 1.8 2.0 1.4 1.7 2.2 2.3
Arm predicted mass (right) 39.9 204.0 311.9 -16.7 -13.0 -13.6 -14.2 -14.7 -13.0 -15.2 -14.2 -13.3 12.4 -12.8 -2.7 -17.2 -10.6 -14.3 -15.3 13.5 17.5 17.0 14.2 12.8 14.1 15.4 17.7
Pulse rate, automated reading 0.9 2.9 7.8 2.6 0.7 2.1 1.1 1.5 2.6 2.8 2.1 2.3 -1.2 0.1 1.5 1.4 -0.7 1.4 1.7 -1.5 -1.8 -1.4 -1.5 -1.4 -1.2 -1.0 -1.7
Alcohol intake frequency. 0.4 0.9 2.7 -0.3 -1.6 -1.3 -0.6 -0.8 -1.4 -0.3 -1.3 -0.4 -0.4 -1.6 1.1 -0.3 -0.9 -0.8 -0.5 0.9 -0.1 0.4 1.5 1.1 0.8 0.9 0.3
Comparative height size at age 10 35.6 196.0 361.0 -15.7 -11.5 -12.5 -13.9 -14.2 -11.8 -12.9 -13.1 -11.3 14.2 -11.0 -2.4 -18.8 -8.3 -14.1 -14.3 12.7 19.0 18.1 13.5 11.8 13.9 17.0 19.0
Number of full sisters 2.2 2.6 5.6 1.1 0.9 1.7 2.0 1.9 1.2 1.6 1.7 0.5 -0.6 0.5 0.8 1.8 0.5 2.1 2.0 -2.0 -2.4 -2.0 -1.7 -1.9 -1.9 -1.6 -2.1
Suffer from ‘nerves’ 0.8 1.2 2.6 -1.3 -1.3 -1.6 -1.3 -1.4 -1.0 -0.8 -1.5 -0.8 -0.0 -1.1 0.2 -0.8 -0.5 -1.3 -1.3 1.2 0.6 0.9 1.4 1.4 1.2 1.3 0.8
Overall health rating 0.9 2.0 7.3 -0.3 -0.1 0.8 1.9 1.6 0.7 1.3 0.8 0.8 -0.5 -0.6 2.7 1.5 0.2 1.8 1.7 -1.7 -2.2 -1.9 -0.8 -1.6 -1.9 -1.0 -1.6
Chest pain or discomfort 2.8 4.1 7.3 -2.6 -2.7 -2.5 -1.8 -2.1 -1.9 -1.8 -2.4 -1.5 2.2 -2.4 0.1 -1.9 -1.0 -1.9 -2.1 2.0 1.5 1.7 2.4 2.1 2.0 2.4 1.8
Had major operations 0.2 0.3 2.5 1.1 -0.1 0.2 0.5 0.4 -0.1 0.9 0.2 0.3 -0.1 0.1 1.6 0.6 0.1 0.2 0.4 -0.2 -0.4 -0.4 -0.1 -0.3 -0.2 -0.5 -0.1
Age at last live birth 2.5 3.6 5.7 -1.7 -1.5 -2.0 -2.0 -2.1 -1.9 -2.1 -2.0 -1.4 2.4 -1.4 -1.5 -2.0 -1.0 -2.0 -1.9 2.0 2.2 2.1 2.0 1.9 2.0 1.8 2.2
Family relationship satisfaction 0.7 0.9 2.8 -1.4 -0.8 -0.9 -0.7 -0.6 -1.5 -1.7 -0.9 -1.3 1.2 -0.8 1.0 -1.3 0.0 -0.3 -0.7 0.4 0.9 0.7 0.6 0.3 0.4 1.0 0.9
Leg pain on walking 0.3 0.4 3.1 0.2 -0.5 0.1 0.2 0.4 0.1 0.5 0.1 -0.1 -1.2 -0.3 1.8 1.1 0.1 0.2 0.0 -0.2 -0.2 -0.0 -0.1 -0.3 -0.4 -1.4 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 2.3 1.1 0.4 1.2 0.8 1.1 0.6 1.5 1.2 0.0 -0.8 0.8 0.7 0.5 0.2 1.1 1.2 -1.0 -1.0 -1.2 -1.0 -1.1 -0.9 -0.8 -0.9
Commuting to job workplace: Car/motor vehicle 1.8 2.0 3.7 0.3 0.6 1.6 1.9 1.8 1.9 1.1 1.7 1.0 -0.3 0.7 -1.1 1.2 1.3 1.8 1.4 -1.8 -1.6 -1.5 -1.6 -1.9 -1.7 -1.0 -1.5
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.1 0.4 0.7 1.1 1.1 0.2 1.1 0.6 0.9 0.7 0.8 0.9 0.3 0.3 0.6 0.2 0.1 -0.3 -0.4 -0.4 -0.6 -0.2 -0.1 -0.0 -0.5
Medication: Aspirin 1.4 1.9 8.0 1.2 1.3 1.0 1.9 1.6 0.6 0.9 1.0 0.5 0.4 1.3 1.1 1.1 2.8 1.3 1.5 -1.4 -1.6 -1.8 -1.2 -1.4 -1.4 -0.8 -1.4
Supplements: Vitamin C 0.5 0.6 1.6 -0.6 -0.9 -0.7 -0.7 -0.6 -0.9 -0.1 -0.7 -0.4 0.5 -0.7 -0.7 -1.0 -0.7 -0.8 -0.5 0.6 0.8 0.6 0.9 0.6 0.8 1.3 1.1
Knee pain experienced in last month 23.5 36.5 59.6 4.5 5.1 5.7 5.9 6.5 5.2 6.2 5.8 4.4 -5.6 4.6 1.3 7.5 3.9 6.8 6.2 -6.3 -7.7 -7.5 -6.3 -6.2 -6.9 -7.2 -7.7
Hypertension (Self-reported) 0.4 1.2 4.0 0.2 -2.0 -0.9 -0.1 -0.8 -1.5 -0.6 -0.8 -1.5 0.3 -1.7 1.0 -1.3 -0.7 -1.0 -0.6 0.9 0.5 0.4 1.3 1.0 1.3 1.8 1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 3.2 0.7 0.2 0.4 0.2 0.2 0.6 0.6 0.3 0.8 -0.8 0.4 1.8 0.6 -0.4 0.1 0.2 -0.2 -0.6 -0.5 -0.2 -0.1 -0.2 -0.1 -0.6
Illnesses of father: Heart disease 0.6 0.8 6.4 -0.2 0.9 0.5 1.0 0.6 0.2 1.0 0.8 0.4 -0.1 1.0 -2.0 0.4 2.5 0.3 0.7 -0.5 -0.7 -1.1 -0.6 -0.6 -0.5 -0.1 -0.7
Illnesses of siblings: Diabetes 1.3 1.6 5.8 -2.0 -2.4 -1.1 -0.4 -0.7 -1.4 -1.2 -1.1 -1.8 -0.4 -2.2 -1.1 -1.2 -2.1 -0.5 -0.5 0.5 0.2 0.3 1.2 0.5 0.7 1.7 0.9
Smoking status: Previous 0.7 1.1 4.9 2.2 0.5 0.7 0.4 0.9 0.9 1.3 0.7 1.2 -1.9 0.6 -0.0 1.5 -0.1 0.8 1.0 -0.5 -1.1 -0.9 -0.6 -0.5 -0.6 -1.5 -1.1
Forced expiratory volume in 1-second (FEV1), predicted 16.0 33.3 61.7 -6.8 -4.4 -5.2 -5.7 -5.7 -4.8 -5.6 -5.6 -4.4 6.7 -4.2 -0.6 -7.9 -3.5 -5.6 -5.9 4.9 7.7 7.4 5.4 4.7 5.5 7.4 7.5
Whole body fat-free mass 42.0 239.8 380.2 -18.2 -13.7 -14.4 -15.5 -15.9 -14.0 -16.2 -15.1 -14.2 13.9 -13.4 -3.0 -19.3 -11.2 -15.5 -16.4 14.4 19.5 18.7 15.1 13.7 15.2 17.2 19.5
Leg fat-free mass (right) 36.3 194.1 313.3 -16.3 -12.3 -12.7 -13.9 -14.2 -12.5 -14.4 -13.3 -12.7 12.6 -12.2 -2.2 -17.7 -10.1 -13.9 -14.7 12.9 17.7 16.9 13.5 12.2 13.7 15.8 17.7
Arm fat percentage (left) 0.6 2.5 6.8 0.6 0.1 1.5 2.6 1.8 1.3 1.6 1.8 0.2 -0.5 -0.1 1.6 1.7 1.8 1.7 1.7 -1.6 -2.3 -2.2 -1.3 -1.7 -1.6 -1.4 -1.8
Average weekly red wine intake 2.0 3.0 6.4 -2.2 0.1 -1.4 -1.4 -2.0 -1.5 -1.6 -1.4 -1.1 1.3 0.2 -2.5 -2.4 0.4 -1.9 -1.9 1.6 2.4 2.2 1.2 1.6 1.8 2.3 2.1
Handedness (chirality/laterality): Left-handed 0.2 0.2 1.8 0.3 0.0 0.0 0.1 -0.2 0.4 0.7 -0.2 0.4 -0.3 0.5 1.3 -0.1 -0.9 -0.3 -0.3 0.2 -0.1 0.1 0.1 0.5 0.3 0.5 -0.2
Mood swings 0.8 1.4 5.4 -1.7 -2.1 -1.5 -1.4 -0.8 -1.5 -1.3 -1.3 -1.9 -0.2 -2.3 1.4 -0.4 -1.1 -0.4 -1.0 0.6 0.2 0.6 1.1 0.7 0.6 0.4 0.6
Loneliness, isolation 0.2 0.3 1.2 0.3 -0.2 0.2 0.5 0.6 -0.0 0.4 0.4 -0.1 0.1 -0.5 1.0 0.3 1.1 0.6 0.6 -0.5 -0.8 -0.4 -0.3 -0.5 -0.5 -0.1 -0.6
Long-standing illness, disability or infirmity 0.3 0.4 1.8 -1.4 -0.9 -0.5 -0.0 -0.2 -0.8 -0.3 -0.7 -0.1 0.1 -1.0 1.2 -0.4 -1.3 0.2 0.1 -0.2 0.0 0.0 0.5 -0.2 -0.2 0.7 0.3
Ever had bowel cancer screening 0.4 0.5 1.9 -1.3 -0.8 -1.0 -1.1 -0.5 -1.4 -0.4 -1.0 -0.2 0.1 -0.8 -0.3 -0.5 -0.1 -0.4 -0.2 0.5 0.1 0.5 0.9 0.6 0.3 0.7 0.1
Diabetes diagnosed by doctor 2.0 3.2 5.5 -2.1 -2.0 -2.0 -1.8 -1.9 -2.1 -2.2 -2.1 -2.4 0.8 -1.9 0.7 -1.7 -1.2 -1.7 -2.0 1.8 1.6 1.4 1.9 1.6 1.6 1.5 1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 1.2 0.2 -0.1 -0.0 -0.0 0.4 -0.5 -0.5 0.3 -0.6 -0.1 0.1 0.4 0.2 1.1 0.5 0.4 -0.2 -0.6 -0.5 -0.4 -0.2 -0.4 -0.5 -0.6
Friendships satisfaction 0.1 0.2 0.9 -0.2 -0.7 0.0 0.4 0.2 -0.2 -0.6 0.3 -0.6 1.0 -0.7 0.1 -0.4 0.8 -0.1 -0.2 -0.1 -0.1 0.0 0.1 -0.1 0.2 0.7 0.1
Qualifications: nursing, teaching 0.4 0.6 1.6 -0.9 -1.0 -0.8 -0.8 -0.5 -1.0 -1.3 -0.7 -1.1 0.9 -0.6 -0.8 -1.0 -0.4 -0.5 -0.6 0.4 0.5 0.5 0.6 0.4 0.5 1.2 0.6
Commuting to job workplace: Walk 6.3 6.8 10.9 -2.0 -2.1 -2.8 -3.3 -3.0 -2.6 -2.8 -2.9 -2.2 0.9 -2.2 -0.3 -2.5 -2.9 -2.8 -2.9 2.9 2.9 2.9 2.8 2.9 2.7 2.2 2.7
Eye problems/disorders: Cataract 1.0 1.1 3.6 -1.0 -1.1 -1.3 -0.9 -0.9 -1.9 -1.4 -1.4 -1.2 1.4 -0.9 0.2 -0.8 -0.4 -0.9 -0.8 0.9 0.8 0.9 1.2 0.9 0.9 0.9 1.0
Mouth/teeth dental problems: Mouth ulcers 1.1 1.7 5.3 2.0 1.7 1.1 1.4 0.8 1.0 1.8 1.1 1.0 -0.7 1.8 0.5 1.6 2.3 0.5 0.7 -0.7 -1.5 -1.8 -1.2 -0.6 -0.7 -1.2 -1.4
Medication for cholesterol 0.1 0.2 0.7 0.6 0.5 0.6 -0.2 0.4 -0.2 0.4 0.4 0.1 0.8 0.5 -0.4 -0.3 -0.6 0.5 0.6 -0.5 0.4 0.4 -0.4 -0.7 -0.5 -0.3 0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.2 0.9 -0.1 -0.6 -0.3 -0.4 -0.2 -0.2 -0.6 -0.5 -0.4 0.4 -0.5 0.3 -0.4 0.5 -0.0 -0.4 0.2 0.6 1.0 0.4 0.1 0.1 0.1 0.6
Back pain experienced in last month 2.7 3.9 8.5 1.5 2.2 2.2 1.7 2.2 2.0 2.9 1.9 2.6 0.3 2.4 -0.3 1.8 0.9 2.3 2.3 -2.3 -1.1 -0.8 -2.1 -2.5 -2.4 -2.2 -1.4
Mineral and other dietary supplements 0.4 0.5 2.7 -0.3 -0.3 -0.4 -0.4 -0.6 -0.7 -0.9 -0.5 -0.8 1.2 -0.6 1.6 -0.7 -0.4 -0.2 -0.4 0.4 1.0 0.7 0.4 0.1 0.3 0.0 1.1
Breast cancer (self-reported) 0.4 0.5 2.4 -1.6 -0.9 -0.7 -1.0 -0.2 -0.3 -0.8 -0.4 -1.2 0.0 -1.1 -1.0 -0.1 -1.1 -0.1 -0.6 0.1 -0.0 0.2 0.3 0.1 0.0 -0.1 0.1
Asthma (self-reported) 2.6 5.2 8.7 -2.4 -2.6 -2.4 -2.2 -2.4 -2.0 -2.1 -2.5 -2.0 0.1 -3.0 -1.3 -2.4 -2.7 -2.2 -2.4 2.4 1.9 1.7 2.6 2.5 2.4 2.7 2.2
Osteoporosis (self-reported) 0.8 1.0 2.3 1.3 0.4 1.3 0.7 1.1 1.4 1.5 1.4 0.9 -0.4 0.0 -1.2 1.2 -0.2 1.0 1.1 -0.8 -0.7 -0.4 -1.0 -0.9 -0.7 -1.5 -0.7
Osteoarthritis (self-reported) 1.5 2.0 4.5 1.2 0.7 1.2 1.5 1.3 1.4 1.9 1.6 1.3 -1.1 1.0 1.5 1.9 2.1 1.1 1.2 -1.0 -1.7 -1.8 -1.2 -1.1 -1.0 -1.8 -1.5
Medication: Aspirin 0.6 0.8 4.8 0.9 0.8 0.6 1.5 1.0 0.4 0.7 0.6 0.2 0.5 0.7 1.4 0.5 2.2 0.6 0.9 -0.7 -0.9 -1.1 -0.6 -0.7 -0.6 -0.2 -0.7
Medication: Gliclazide 1.4 1.5 4.7 -1.6 -1.2 -1.1 -1.3 -0.9 -1.6 -1.9 -1.2 -2.2 0.7 -1.0 -1.3 -1.7 -0.6 -0.8 -1.1 0.9 1.3 1.1 1.0 0.7 0.9 1.3 1.4
Illnesses of father: None of the above (group 1) 0.3 0.3 2.4 0.4 -0.3 -0.2 -0.5 -0.6 0.0 0.1 -0.4 0.5 0.2 -0.1 -0.0 0.1 -1.6 -0.5 -0.5 0.7 0.7 0.9 0.5 0.7 0.6 -0.2 0.6
Smoking status: Current 0.2 0.2 1.9 0.7 -0.4 0.3 0.0 0.2 0.8 0.7 0.5 0.6 -1.4 -0.8 0.1 0.2 -0.6 0.2 0.3 -0.1 -0.2 0.3 -0.0 -0.1 -0.0 -0.1 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.8 3.9 10.3 1.3 1.7 1.7 2.0 1.4 1.6 3.0 1.7 1.6 -2.5 1.9 0.9 3.2 1.2 1.4 1.3 -1.4 -2.4 -2.5 -1.8 -1.3 -1.6 -3.0 -2.4
Whole body water mass 41.5 236.6 372.5 -18.1 -13.7 -14.4 -15.4 -15.8 -14.0 -16.2 -15.0 -14.2 13.7 -13.4 -3.0 -19.1 -11.3 -15.3 -16.3 14.3 19.3 18.5 15.0 13.6 15.0 17.0 19.3
Leg predicted mass (right) 36.4 194.1 313.3 -16.3 -12.3 -12.7 -13.9 -14.2 -12.5 -14.3 -13.2 -12.8 12.7 -12.2 -2.1 -17.7 -10.1 -13.9 -14.7 12.9 17.7 16.9 13.5 12.2 13.7 15.8 17.7
Arm fat mass (left) 3.0 12.2 24.5 -5.0 -4.0 -3.2 -2.4 -3.2 -3.1 -3.7 -3.1 -4.0 3.9 -4.1 0.6 -4.3 -1.7 -3.1 -3.4 2.9 3.8 3.8 3.5 2.7 3.2 4.0 4.3
Number of self-reported non-cancer illnesses 0.3 0.6 3.5 -0.4 -1.8 0.1 0.3 0.1 -0.3 0.4 0.0 -0.4 0.6 -1.9 1.3 -0.6 -1.4 0.1 0.1 -0.2 -0.2 0.3 0.5 -0.1 0.2 1.2 0.4
Average weekly champagne plus white wine intake 3.1 4.2 7.3 -1.2 -1.9 -2.2 -1.7 -2.0 -2.1 -2.0 -2.3 -2.3 1.0 -1.9 -0.2 -2.1 -1.8 -2.3 -2.2 2.4 2.5 2.3 2.4 2.2 2.4 1.8 2.7
Miserableness 0.2 0.3 0.6 -0.3 0.1 0.2 0.4 0.6 0.4 0.3 0.5 0.1 -0.8 -0.3 0.1 0.5 0.7 0.7 0.5 -0.7 -0.7 -0.7 -0.6 -0.8 -0.7 -0.6 -0.5
Guilty feelings 1.3 2.0 7.0 -1.0 -2.4 -1.5 -1.5 -1.2 -1.4 -1.0 -1.6 -1.7 -0.7 -2.3 -0.8 -0.7 -2.6 -1.0 -1.4 1.2 0.6 1.1 1.5 1.3 1.3 0.8 1.0
Wears glasses or contact lenses 0.4 0.4 2.6 -1.6 -0.1 -0.8 -0.9 -0.7 -0.3 -0.7 -0.9 -0.2 -0.8 -0.2 0.2 0.2 -0.8 -0.5 -0.8 0.7 0.5 0.5 0.5 0.8 0.4 -0.4 0.2
Ever taken oral contraceptive pill 1.7 1.9 3.0 1.4 1.7 1.6 1.4 1.4 1.5 1.6 1.7 0.8 -0.4 1.5 -1.6 1.4 0.9 1.2 1.1 -1.3 -1.4 -1.7 -1.6 -1.3 -1.2 -1.5 -1.5
Hearing aid user 0.4 0.5 3.2 0.6 1.3 0.7 0.3 0.2 0.9 0.9 0.6 0.9 -0.0 1.3 1.8 0.3 -0.0 -0.2 -0.0 0.1 0.2 0.2 -0.5 0.1 0.1 -0.5 -0.4
Mother’s age at death 0.3 0.3 1.7 0.6 1.0 0.6 0.6 0.1 0.4 0.6 0.6 0.7 1.3 1.2 -0.5 0.1 1.0 -0.0 0.0 -0.2 0.1 -0.0 -0.5 -0.1 -0.1 0.1 -0.2
Financial situation satisfaction 0.3 0.4 2.0 -0.5 -0.9 -0.4 -0.4 0.0 -0.6 -0.2 -0.5 -0.4 -1.1 -1.0 1.4 0.5 -1.1 0.4 0.0 -0.1 -0.3 0.2 0.3 -0.1 -0.3 -0.6 -0.1
Tinnitus: Yes, now most or all of the time 1.8 2.1 4.6 -2.1 -1.3 -1.3 -1.6 -1.7 -1.1 -1.2 -1.3 -1.4 0.5 -1.1 0.8 -1.5 -0.9 -1.8 -2.0 1.6 1.5 1.4 1.4 1.6 1.6 1.4 1.4
Commuting to job workplace: Public transport 1.3 1.5 3.1 -1.3 -0.9 -1.2 -1.6 -1.6 -0.9 -1.4 -1.3 -1.0 -0.3 -0.9 -0.3 -1.3 -1.8 -1.4 -1.7 1.4 1.2 0.9 1.1 1.4 1.2 1.3 1.0
Eye problems/disorders: Glaucoma 1.7 2.0 4.8 2.0 1.8 1.3 0.9 1.3 0.9 1.2 1.4 1.1 -1.0 1.8 -1.3 1.6 2.2 1.2 1.3 -1.2 -1.3 -1.4 -1.6 -1.2 -1.2 -1.8 -1.6
Medication: Blood pressure 2.1 4.0 6.8 -1.6 -2.6 -2.4 -1.2 -2.1 -1.7 -2.4 -2.2 -2.1 0.3 -2.5 0.4 -1.9 -1.1 -2.2 -2.3 2.1 1.6 1.5 2.3 2.2 2.3 2.4 2.0
Pain type(s) experienced in last month: Hip pain 0.2 0.3 1.5 -0.4 0.4 0.3 1.1 0.6 0.2 0.3 0.5 0.2 0.1 -0.1 -0.8 -0.4 1.2 0.2 0.6 -0.4 -0.2 -0.6 -0.2 -0.5 -0.2 0.6 0.1
Supplements: Fish oil (including cod liver oil) 0.2 0.3 3.2 0.1 -0.1 0.0 0.2 0.2 -0.3 0.2 0.0 0.1 -1.8 0.3 -1.4 0.2 -0.1 -0.2 -0.0 0.0 -0.6 -0.5 0.1 0.2 0.1 0.2 -0.5
High cholesterol (Self-reported) 2.1 3.8 7.8 2.3 2.4 1.7 2.5 1.7 1.7 1.8 1.7 2.2 -1.2 2.7 0.9 1.6 2.8 1.5 1.9 -1.7 -2.1 -2.5 -1.8 -1.5 -1.7 -0.9 -2.2
Medication: Bendroflumethiazide 1.5 2.3 4.2 -0.6 -2.0 -1.6 -1.0 -1.5 -1.4 -1.6 -1.8 -1.9 0.2 -1.8 2.0 -1.2 -1.7 -1.5 -1.5 1.5 1.0 1.0 1.7 1.6 1.7 1.6 1.4
Medication: Paracetamol 0.2 0.3 0.8 -0.3 -0.3 -0.7 -0.2 -0.4 -0.7 -0.8 -0.6 -0.6 -0.7 -0.5 0.7 -0.7 0.4 -0.6 -0.6 0.6 0.2 0.5 0.6 0.8 0.7 0.9 0.2
Medication: Lisinopril 0.3 0.4 2.3 -0.7 -1.1 -0.6 -0.0 -0.2 -0.9 -0.8 -0.5 -1.5 0.4 -1.1 1.1 -0.4 -0.5 0.1 -0.2 0.1 -0.2 -0.4 0.4 0.0 0.2 0.5 0.2
Medication: Atorvastatin 1.4 1.7 3.6 0.8 0.8 1.2 1.9 1.6 1.2 1.2 1.0 1.2 -1.2 0.6 1.6 1.4 0.4 1.4 1.4 -1.5 -1.5 -1.4 -1.1 -1.5 -1.7 -1.1 -1.4
Illnesses of father: High blood pressure 0.9 1.2 4.6 -0.5 -1.4 -1.1 -0.6 -0.7 -1.7 -1.4 -1.0 -2.1 -0.3 -1.4 1.6 -1.0 -0.7 -0.9 -1.0 1.0 0.6 0.3 1.1 0.9 1.0 0.8 0.9
Alcohol drinker status: Never 1.4 1.6 2.6 1.1 0.9 1.6 1.4 1.4 1.1 1.3 1.4 0.8 -1.4 0.7 0.9 1.1 0.2 1.5 1.2 -1.5 -1.6 -1.6 -1.4 -1.4 -1.5 -1.0 -1.6
Ever smoked 0.2 0.4 2.2 0.8 -0.8 -0.3 -0.9 -0.1 -0.1 0.3 -0.2 0.2 -1.5 -0.9 -0.7 0.2 -1.4 0.1 0.3 0.3 -0.1 0.4 0.4 0.3 0.2 -0.3 0.0
Basal metabolic rate 36.7 203.4 320.4 -17.0 -12.7 -13.3 -14.0 -14.6 -12.9 -14.9 -13.8 -13.2 13.0 -12.5 -2.5 -17.8 -10.2 -14.2 -15.1 13.2 17.9 17.1 13.9 12.5 14.0 16.0 17.9
Leg fat percentage (left) 2.6 9.4 22.8 2.4 1.2 2.5 4.3 3.4 2.5 2.8 3.0 1.7 -1.9 1.0 1.0 4.2 2.9 3.3 3.4 -2.9 -4.8 -4.4 -2.6 -2.8 -3.0 -3.4 -4.1
Arm fat-free mass (left) 36.9 187.4 289.0 -16.4 -12.3 -13.0 -13.5 -14.0 -12.4 -14.6 -13.5 -12.7 12.4 -12.2 -2.6 -16.7 -9.9 -13.6 -14.5 12.7 16.9 16.4 13.5 12.1 13.4 15.0 17.0
Number of operations (self-reported) 0.7 1.0 3.1 1.1 -0.5 0.7 1.3 1.2 0.5 1.2 0.8 0.0 0.0 -0.3 1.5 1.2 -0.3 1.1 1.0 -1.0 -1.8 -1.3 -0.6 -0.9 -0.9 -0.6 -1.3
Average weekly beer plus cider intake 3.6 5.2 9.2 2.4 1.4 2.7 2.7 2.4 2.7 3.0 2.7 2.5 -1.7 1.2 0.2 2.5 0.6 2.4 2.7 -2.3 -2.4 -2.3 -2.3 -2.3 -2.2 -2.5 -2.2
Irritability 0.9 1.6 4.0 -1.7 -1.0 -2.0 -1.5 -1.4 -1.9 -1.3 -1.6 -1.8 0.3 -0.8 0.7 -0.3 -0.2 -1.3 -1.5 1.5 0.7 0.8 1.3 1.5 1.2 -0.1 0.7
Risk taking 0.4 0.6 2.6 -1.6 -1.1 -0.7 -1.1 -0.2 -1.0 -1.2 -0.8 -1.2 0.6 -0.9 -1.0 -0.4 0.0 -0.0 -0.4 0.1 0.5 0.3 0.5 -0.0 -0.0 0.4 0.7
Ever had prostate specific antigen (PSA) test 1.2 1.4 2.9 -1.2 -0.2 -1.3 -0.9 -1.4 -1.4 -0.7 -1.2 -0.6 0.9 -0.2 -0.8 -1.3 -0.0 -1.7 -1.4 1.6 1.4 1.0 1.2 1.6 1.6 1.2 1.3
Fractured/broken bones in last 5 years 0.3 0.3 2.7 1.0 0.8 0.4 0.2 0.3 0.4 0.2 0.4 -0.1 -1.6 1.0 -0.3 0.1 1.0 0.2 0.2 -0.2 -0.1 -0.3 -0.6 -0.3 -0.2 -0.2 -0.3
Age started oral contraceptive pill 0.3 0.4 2.0 -1.4 0.1 -0.8 -0.7 -0.6 0.0 -0.1 -1.0 1.1 -0.7 0.3 -1.2 0.5 -0.8 -0.3 -0.4 0.3 0.2 0.7 0.4 0.6 0.0 -0.3 -0.1
Diastolic blood pressure, automated reading 0.2 0.5 2.5 -0.7 -1.1 -0.4 -0.2 -0.5 -0.5 0.1 0.0 -0.9 -0.0 -1.6 -0.8 -0.9 0.1 -0.8 -0.4 0.6 0.2 0.1 0.7 0.6 0.9 1.2 0.6
Ever depressed for a whole week 1.1 1.4 3.6 0.6 0.9 1.8 1.3 1.4 1.7 1.8 1.9 1.1 0.0 0.6 0.0 0.6 0.7 1.3 1.2 -1.4 -1.0 -0.8 -1.4 -1.3 -1.0 -0.5 -1.0
Unable to work because of sickness or disability 1.9 2.5 5.4 1.2 0.7 1.6 1.7 1.8 1.6 2.1 1.9 1.6 0.3 0.1 2.3 1.6 0.4 1.8 2.1 -1.9 -1.7 -1.1 -1.4 -1.9 -1.8 -1.6 -1.4
Commuting to job workplace: Cycle 2.3 2.8 7.1 -1.1 -0.5 -1.4 -2.3 -2.1 -1.7 -1.3 -1.4 -1.0 1.1 -0.6 0.1 -2.1 -0.1 -2.1 -1.8 1.9 2.6 2.7 1.4 1.8 2.0 1.4 2.2
Myopia 6.7 9.7 15.2 -3.0 -2.5 -3.6 -3.9 -3.9 -3.5 -3.4 -3.6 -2.8 1.0 -2.2 0.5 -3.3 -2.5 -3.4 -3.3 3.5 3.3 3.0 3.2 3.5 3.3 2.9 3.1
Vascular/heart problems diagnosed by doctor 0.6 1.6 5.6 0.5 2.4 1.1 -0.1 0.7 1.6 1.0 1.0 2.1 -0.7 2.3 -2.0 1.1 0.8 0.9 0.8 -0.9 -0.2 -0.1 -1.4 -0.9 -1.2 -1.6 -1.0
Cholesterol lowering medication 0.6 0.8 3.5 0.9 1.0 0.3 1.5 0.4 0.9 0.5 0.2 1.1 -1.2 1.3 1.4 0.8 1.9 0.2 0.4 -0.3 -0.9 -1.2 -0.4 -0.0 -0.3 -0.0 -0.9
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 1.1 0.6 0.3 0.2 0.3 0.0 0.1 0.4 0.2 -0.0 -0.3 0.4 1.0 -0.2 0.5 -0.3 -0.2 0.3 -0.1 -0.4 0.1 0.4 0.4 0.4 -0.0
Pain experienced in last month 2.2 3.8 6.4 -1.4 -1.4 -1.7 -1.8 -2.4 -1.0 -2.1 -1.8 -1.1 1.9 -1.3 0.0 -2.2 -0.7 -2.4 -2.4 2.3 2.4 2.4 1.9 2.4 2.5 2.3 2.2
Supplements: Calcium 0.1 0.2 0.6 -0.2 -0.1 0.3 0.1 0.5 0.1 0.2 0.3 -0.2 0.3 -0.3 0.8 -0.0 -0.3 0.6 0.4 -0.7 -0.5 -0.3 -0.3 -0.6 -0.6 0.3 -0.4
Basal cell carcinoma (self-reported) 0.4 0.5 2.9 -0.2 0.7 0.1 0.6 0.8 0.0 1.3 0.2 0.3 1.2 1.1 -1.7 0.1 1.1 0.5 0.8 -0.6 -0.4 -0.6 -0.3 -0.6 -0.5 0.2 -0.4
Heart attack/myocardial infarction (self-reported) 0.3 0.4 4.1 -0.7 -0.8 -0.2 0.5 -0.0 0.1 0.3 -0.1 -0.2 0.7 -0.7 2.0 -0.4 -0.8 -0.2 -0.0 0.0 -0.3 0.1 0.4 0.2 0.3 0.9 0.0
Deep venous thrombosis (DVT) (self-reported) 1.8 2.4 12.2 -2.3 -1.6 -0.5 -1.2 -1.2 -0.2 -1.5 -1.2 -1.3 0.4 -1.8 -0.1 -1.3 -3.5 -1.1 -2.1 1.1 1.9 2.1 1.2 1.1 1.1 0.8 1.9
Heart disease (siblings) 0.3 0.3 2.2 -0.8 -0.5 0.4 0.4 0.5 0.3 1.1 0.6 -0.3 -0.7 -0.3 -1.5 0.3 -0.3 0.4 0.4 -0.5 -0.5 -0.3 -0.3 -0.5 -0.3 -0.4 -0.2
Alcohol drinker status: Previous 1.2 1.4 3.3 -0.2 -1.1 -1.2 -0.9 -1.1 -0.4 -0.7 -1.3 0.5 1.6 -1.2 0.4 -1.2 -1.5 -1.2 -0.8 1.2 1.2 1.6 1.5 1.3 1.3 1.8 1.3
Pack years of smoking 0.9 1.3 3.0 -1.7 -1.6 -0.7 -0.9 -0.8 -0.6 -0.2 -0.9 -0.7 1.7 -1.5 1.4 -1.2 -1.3 -0.8 -0.9 0.8 1.1 1.5 1.2 0.7 0.9 1.2 1.3
Impedance of whole body 6.2 31.8 47.9 6.7 6.1 5.5 5.3 5.6 5.6 6.9 5.6 6.1 -4.2 6.3 0.7 6.3 5.1 5.4 5.8 -5.2 -6.0 -5.9 -5.7 -5.1 -5.4 -5.7 -6.3
Leg fat mass (left) 1.6 6.2 13.5 -3.7 -3.2 -2.4 -1.3 -2.1 -2.3 -2.8 -2.2 -3.2 3.0 -3.3 0.1 -2.8 -0.8 -2.1 -2.3 2.1 2.3 2.3 2.6 1.9 2.3 2.7 2.8
Arm predicted mass (left) 36.9 187.8 289.0 -16.4 -12.3 -13.0 -13.5 -14.0 -12.4 -14.7 -13.6 -12.7 12.3 -12.2 -2.7 -16.9 -9.8 -13.6 -14.5 12.7 16.9 16.3 13.5 12.1 13.4 15.2 17.0