TWAS hub - CEP250

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0230	0.0130	4.4e-03	-0.001	0.004	0.002	0.003	-0.001	3.8e-01	1.0e-01	1.7e-01	1.2e-01	5.2e-01
2	GTEx	Brain Caudate basal ganglia	0.2600	0.1360	3.0e-03	0.002	NA	0.076	NA	0.051	2.7e-01	NA	3.2e-03	NA	1.4e-02
3	GTEx	Brain Cerebellar Hemisphere	0.5090	0.1010	8.6e-10	0.402	NA	0.339	NA	0.357	2.0e-11	NA	1.6e-09	NA	4.7e-10
4	GTEx	Brain Cerebellum	0.3900	0.1000	2.3e-09	0.163	NA	0.243	NA	0.239	1.5e-05	NA	8.8e-08	NA	1.1e-07
5	GTEx	Brain Cortex	0.1370	0.0570	3.0e-04	0.165	NA	0.154	NA	0.152	2.6e-05	NA	4.9e-05	NA	5.7e-05
6	GTEx	Brain Frontal Cortex BA9	0.4656	0.1203	1.1e-05	0.175	NA	0.010	NA	0.072	2.1e-05	NA	1.7e-01	NA	6.0e-03
7	GTEx	Brain Hypothalamus	0.1800	0.0950	2.1e-03	-0.012	NA	-0.008	NA	-0.001	7.9e-01	NA	5.4e-01	NA	3.4e-01
8	GTEx	Brain Nucleus accumbens basal ganglia	0.1540	0.0850	3.6e-03	0.093	NA	0.010	NA	0.047	1.8e-03	NA	1.7e-01	NA	2.1e-02
9	GTEx	Brain Putamen basal ganglia	0.1930	0.1130	9.6e-03	-0.012	NA	-0.012	NA	-0.009	8.8e-01	NA	8.1e-01	NA	5.9e-01
10	GTEx	Esophagus Mucosa	0.2870	0.0890	2.1e-04	-0.001	NA	-0.004	NA	-0.003	4.0e-01	NA	9.3e-01	NA	5.3e-01
11	GTEx	Esophagus Muscularis	0.1330	0.0600	5.1e-04	0.037	NA	0.018	NA	0.025	2.7e-03	NA	2.7e-02	NA	1.1e-02
12	GTEx	Liver	0.2980	0.1010	7.5e-03	-0.006	NA	-0.005	NA	-0.002	5.3e-01	NA	4.7e-01	NA	3.7e-01
13	GTEx	Muscle Skeletal	0.0900	0.0388	7.0e-07	0.039	NA	0.063	NA	0.067	1.1e-04	NA	8.2e-07	NA	3.6e-07
14	GTEx	Nerve Tibial	0.6105	0.0760	2.6e-11	0.054	NA	0.022	NA	0.049	1.1e-04	NA	9.6e-03	NA	2.1e-04
15	ROSMAP	Brain Pre-frontal Cortex	0.1454	0.0413	1.5e-13	0.144	0.116	0.125	0.126	0.130	4.0e-18	1.1e-14	1.0e-15	6.5e-16	2.3e-16
16	YFS	Blood	0.1453	0.0423	0.0e+00	0.124	0.121	0.122	0.128	0.132	3.1e-38	1.5e-37	1.1e-37	1.2e-39	9.2e-41
17	TCGA	Breast Invasive Carcinoma	0.0145	0.0081	1.4e-04	0.020	0.019	0.019	NA	0.019	4.3e-05	5.8e-05	6.3e-05	NA	6.3e-05
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.0200	0.0118	1.3e-03	0.013	0.025	0.019	NA	0.017	1.3e-02	8.0e-04	2.9e-03	NA	4.6e-03
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0275	0.0192	1.9e-03	0.006	0.029	0.020	NA	0.018	5.9e-02	2.6e-04	2.2e-03	NA	3.6e-03
20	TCGA	Liver Hepatocellular Carcinoma	0.0850	0.0510	2.4e-04	0.064	0.049	0.011	NA	0.056	5.7e-04	2.4e-03	9.6e-02	NA	1.2e-03
21	TCGA	Lung Adenocarcinoma	0.0184	0.0115	3.4e-03	0.019	0.017	0.012	NA	0.015	2.6e-03	4.0e-03	1.2e-02	NA	6.1e-03
22	TCGA	Prostate Adenocarcinoma	0.0800	0.0326	6.8e-14	0.153	0.141	0.148	NA	0.144	9.7e-16	1.5e-14	3.1e-15	NA	6.8e-15
23	TCGA	Testicular Germ Cell Tumors	0.1010	0.0700	9.4e-03	-0.001	0.046	0.001	NA	0.011	3.6e-01	9.8e-03	3.0e-01	NA	1.3e-01
24	TCGA	Thyroid Carcinoma	0.0450	0.0270	4.5e-05	0.030	0.042	0.038	NA	0.034	5.9e-04	5.8e-05	1.3e-04	NA	2.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Sitting height	56.2	399.2	681.2	-23.3	-15.8	-18.7	-19.9	-20.7	-18.3	-21.0	-19.9	-17.4	19.8	-14.8	-4.3	-25.4	-12.0	-20.2	-21.4	18.6	26.1	24.5	19.2	17.7	19.5	22.7	25.5
Standing height	45.6	452.8	788.9	-24.3	-17.2	-19.7	-21.9	-22.1	-18.7	-21.0	-21.0	-17.9	19.5	-16.3	-4.4	-27.0	-14.7	-21.7	-22.8	19.9	28.1	26.7	20.6	18.9	21.1	24.1	27.5
Trunk predicted mass	45.3	259.0	408.0	-18.9	-14.1	-15.2	-16.2	-16.6	-14.6	-17.0	-15.9	-14.7	14.3	-13.7	-3.4	-19.9	-11.8	-16.1	-17.2	15.0	20.2	19.3	15.7	14.3	15.8	17.8	20.1
Trunk fat-free mass	44.9	257.9	408.0	-18.9	-14.1	-15.1	-16.2	-16.5	-14.6	-16.9	-15.9	-14.6	14.3	-13.7	-3.4	-19.9	-11.8	-16.0	-17.1	14.9	20.2	19.3	15.7	14.2	15.7	17.8	20.1
Height	43.8	844.4	1444.0	-34.2	-23.9	-27.2	-29.5	-30.0	-26.2	-28.5	-28.8	-24.6	27.5	-22.5	-6.2	-37.0	-19.6	-29.2	-30.9	26.7	38.0	36.3	28.2	25.2	28.3	33.3	37.5
Whole body fat-free mass	42.0	239.8	380.2	-18.2	-13.7	-14.4	-15.5	-15.9	-14.0	-16.2	-15.1	-14.2	13.9	-13.4	-3.0	-19.3	-11.2	-15.5	-16.4	14.4	19.5	18.7	15.1	13.7	15.2	17.2	19.5
Whole body water mass	41.5	236.6	372.5	-18.1	-13.7	-14.4	-15.4	-15.8	-14.0	-16.2	-15.0	-14.2	13.7	-13.4	-3.0	-19.1	-11.3	-15.3	-16.3	14.3	19.3	18.5	15.0	13.6	15.0	17.0	19.3
Arm predicted mass (right)	39.9	204.0	311.9	-16.7	-13.0	-13.6	-14.2	-14.7	-13.0	-15.2	-14.2	-13.3	12.4	-12.8	-2.7	-17.2	-10.6	-14.3	-15.3	13.5	17.5	17.0	14.2	12.8	14.1	15.4	17.7
Arm fat-free mass (right)	39.2	201.1	306.2	-16.9	-12.9	-13.4	-14.1	-14.6	-12.8	-15.1	-14.0	-13.2	12.6	-12.8	-2.7	-17.1	-10.7	-14.1	-15.1	13.3	17.4	16.9	14.0	12.7	14.0	15.2	17.5
Arm fat-free mass (left)	36.9	187.4	289.0	-16.4	-12.3	-13.0	-13.5	-14.0	-12.4	-14.6	-13.5	-12.7	12.4	-12.2	-2.6	-16.7	-9.9	-13.6	-14.5	12.7	16.9	16.4	13.5	12.1	13.4	15.0	17.0
Arm predicted mass (left)	36.9	187.8	289.0	-16.4	-12.3	-13.0	-13.5	-14.0	-12.4	-14.7	-13.6	-12.7	12.3	-12.2	-2.7	-16.9	-9.8	-13.6	-14.5	12.7	16.9	16.3	13.5	12.1	13.4	15.2	17.0
Basal metabolic rate	36.7	203.4	320.4	-17.0	-12.7	-13.3	-14.0	-14.6	-12.9	-14.9	-13.8	-13.2	13.0	-12.5	-2.5	-17.8	-10.2	-14.2	-15.1	13.2	17.9	17.1	13.9	12.5	14.0	16.0	17.9
Leg predicted mass (right)	36.4	194.1	313.3	-16.3	-12.3	-12.7	-13.9	-14.2	-12.5	-14.3	-13.2	-12.8	12.7	-12.2	-2.1	-17.7	-10.1	-13.9	-14.7	12.9	17.7	16.9	13.5	12.2	13.7	15.8	17.7
Leg fat-free mass (right)	36.3	194.1	313.3	-16.3	-12.3	-12.7	-13.9	-14.2	-12.5	-14.4	-13.3	-12.7	12.6	-12.2	-2.2	-17.7	-10.1	-13.9	-14.7	12.9	17.7	16.9	13.5	12.2	13.7	15.8	17.7
Comparative height size at age 10	35.6	196.0	361.0	-15.7	-11.5	-12.5	-13.9	-14.2	-11.8	-12.9	-13.1	-11.3	14.2	-11.0	-2.4	-18.8	-8.3	-14.1	-14.3	12.7	19.0	18.1	13.5	11.8	13.9	17.0	19.0
Leg fat-free mass (left)	34.3	181.8	295.8	-16.0	-11.8	-12.3	-13.3	-13.7	-12.2	-14.0	-12.8	-12.6	12.4	-11.7	-2.0	-17.2	-9.4	-13.5	-14.2	12.4	17.1	16.3	13.1	11.7	13.3	15.3	17.1
Leg predicted mass (left)	34.1	180.9	295.8	-15.9	-11.8	-12.3	-13.2	-13.7	-12.1	-13.9	-12.8	-12.5	12.4	-11.6	-2.0	-17.2	-9.4	-13.4	-14.2	12.4	17.1	16.3	13.0	11.7	13.2	15.3	17.1
Knee pain experienced in last month	23.5	36.5	59.6	4.5	5.1	5.7	5.9	6.5	5.2	6.2	5.8	4.4	-5.6	4.6	1.3	7.5	3.9	6.8	6.2	-6.3	-7.7	-7.5	-6.3	-6.2	-6.9	-7.2	-7.7
Hand grip strength (right)	21.5	58.5	108.2	-8.9	-5.6	-6.8	-7.8	-8.0	-6.8	-7.3	-7.1	-6.1	7.0	-5.2	-3.2	-10.0	-4.8	-8.0	-8.0	7.3	10.4	9.6	7.2	7.0	8.0	8.9	10.1
Weight	19.3	95.1	152.2	-11.9	-9.1	-9.0	-8.9	-9.8	-8.8	-10.1	-9.3	-9.4	9.5	-9.0	-1.0	-12.3	-6.1	-9.6	-10.2	8.9	12.1	11.6	9.6	8.4	9.6	11.2	12.3
Forced expiratory volume in 1-second (FEV1), predicted	16.0	33.3	61.7	-6.8	-4.4	-5.2	-5.7	-5.7	-4.8	-5.6	-5.6	-4.4	6.7	-4.2	-0.6	-7.9	-3.5	-5.6	-5.9	4.9	7.7	7.4	5.4	4.7	5.5	7.4	7.5
Lung FVC	14.3	72.7	118.8	9.7	6.2	8.4	8.2	8.8	7.7	10.3	8.5	7.5	-10.3	6.0	0.9	10.7	3.3	8.7	9.1	-8.1	-10.9	-9.9	-8.1	-7.7	-8.3	-9.5	-10.5
Hand grip strength (left)	13.7	36.2	72.4	-7.0	-4.3	-5.2	-6.1	-6.2	-5.3	-5.8	-5.5	-4.6	5.5	-3.5	-2.1	-8.2	-3.5	-6.2	-6.1	5.7	8.5	7.9	5.5	5.3	6.2	7.2	8.1
Tanning	13.2	161.3	428.5	-7.5	-11.3	-10.8	-12.4	-12.5	-11.8	-20.7	-12.8	-9.7	14.0	-12.2	1.4	-15.3	-7.5	-12.4	-13.2	11.5	15.8	14.2	12.4	10.8	12.1	14.5	16.1
Peak expiratory flow (PEF)	12.6	29.3	51.9	-6.3	-4.2	-5.2	-5.5	-5.8	-4.9	-4.5	-5.4	-4.2	4.6	-4.0	-1.9	-6.7	-3.5	-5.8	-5.9	5.3	7.2	6.7	5.5	5.0	5.6	6.2	7.2
Hip circumference	12.0	51.8	85.2	-8.6	-6.9	-6.8	-6.3	-7.1	-6.6	-7.4	-6.7	-6.9	7.5	-6.9	-1.3	-9.2	-3.8	-7.1	-7.1	6.6	8.9	8.5	7.1	6.2	7.2	8.4	9.2
Impedance of leg (right)	9.3	45.0	70.5	7.7	6.6	6.0	6.8	6.8	6.1	7.3	6.2	6.4	-5.5	6.8	0.5	8.4	5.9	6.6	7.0	-6.2	-8.0	-7.7	-6.6	-5.9	-6.6	-7.5	-8.1
Impedance of leg (left)	8.9	43.2	69.5	7.6	6.2	5.9	6.5	6.6	6.2	7.3	6.1	6.7	-5.3	6.3	0.2	8.3	5.4	6.5	7.0	-6.1	-8.0	-7.6	-6.3	-5.7	-6.4	-7.3	-8.1
Alcohol usually taken with meals	8.3	13.5	19.3	-2.9	-2.6	-4.3	-3.7	-4.1	-4.2	-4.4	-4.2	-3.8	1.7	-2.4	-2.1	-3.8	-0.8	-4.2	-4.3	4.2	3.8	3.5	3.9	4.3	4.2	3.8	3.8
LDL Cholesterol	6.8	10.7	17.9	3.6	4.2	3.7	3.4	3.3	3.5	3.5	3.7	3.0	-1.2	3.7	0.1	3.4	2.3	3.0	3.3	-3.2	-3.1	-3.6	-3.7	-3.2	-3.2	-3.4	-3.4
Myopia	6.7	9.7	15.2	-3.0	-2.5	-3.6	-3.9	-3.9	-3.5	-3.4	-3.6	-2.8	1.0	-2.2	0.5	-3.3	-2.5	-3.4	-3.3	3.5	3.3	3.0	3.2	3.5	3.3	2.9	3.1
Commuting to job workplace: Walk	6.3	6.8	10.9	-2.0	-2.1	-2.8	-3.3	-3.0	-2.6	-2.8	-2.9	-2.2	0.9	-2.2	-0.3	-2.5	-2.9	-2.8	-2.9	2.9	2.9	2.9	2.8	2.9	2.7	2.2	2.7
Relative age voice broke	6.2	9.5	20.2	2.9	2.5	2.9	2.8	3.2	2.9	3.0	2.9	2.0	-3.5	2.7	0.1	4.5	0.5	3.2	2.8	-3.0	-3.7	-3.5	-3.2	-2.9	-3.4	-4.5	-3.8
Impedance of whole body	6.2	31.8	47.9	6.7	6.1	5.5	5.3	5.6	5.6	6.9	5.6	6.1	-4.2	6.3	0.7	6.3	5.1	5.4	5.8	-5.2	-6.0	-5.9	-5.7	-5.1	-5.4	-5.7	-6.3
Qualifications: CSEs or equivalent	6.1	8.0	12.5	3.5	2.5	3.1	2.5	3.2	3.1	3.0	3.2	2.9	-2.3	2.3	-1.6	2.7	2.0	3.1	3.2	-3.0	-2.9	-2.7	-3.0	-3.0	-2.9	-2.6	-2.9
Hair Pigment	5.6	160.2	461.7	7.6	10.6	10.5	12.1	12.4	12.5	21.5	12.5	11.0	-15.5	12.3	-0.0	15.4	6.0	12.0	12.9	-11.1	-15.8	-13.8	-12.0	-10.1	-11.6	-13.9	-16.1
Medication: Lansoprazole	5.4	6.1	10.2	1.7	1.7	2.5	2.9	2.5	2.1	2.9	2.6	1.6	-2.5	1.8	1.5	3.0	0.1	2.6	2.4	-2.5	-3.2	-3.1	-2.5	-2.5	-2.7	-2.8	-3.1
Fluid intelligence score	5.2	10.8	18.2	-4.3	-3.1	-3.7	-2.6	-3.5	-3.5	-3.6	-3.5	-3.5	3.6	-3.0	-0.3	-3.1	-1.3	-3.5	-3.7	3.5	3.5	3.0	3.5	3.3	3.4	2.8	3.7
Trunk fat mass	5.1	21.9	38.1	-6.2	-4.7	-4.2	-3.6	-4.5	-4.0	-4.4	-4.1	-4.7	5.0	-4.7	0.3	-6.0	-2.4	-4.6	-4.8	4.2	5.7	5.5	4.6	3.9	4.6	5.5	6.0
Forced vital capacity (FVC), Best measure	4.8	17.7	31.9	-4.5	-3.8	-3.6	-4.5	-4.5	-3.6	-3.0	-4.0	-3.5	2.4	-3.6	-1.3	-5.0	-3.8	-4.4	-4.7	4.1	5.6	5.5	4.2	4.0	4.5	4.5	5.7
Forced expiratory volume in 1-second (FEV1)	4.6	15.6	25.5	-4.6	-3.7	-3.8	-4.1	-4.3	-4.0	-3.0	-4.1	-3.9	0.9	-3.6	-0.9	-4.3	-3.8	-4.1	-4.5	3.9	4.8	4.6	4.1	3.7	4.1	3.8	5.0
Type 2 Diabetes (T2D) (2012)	4.5	5.2	9.3	-2.7	-2.4	-2.3	-2.0	-2.4	-2.5	-2.1	-2.4	-3.1	1.4	-2.3	0.0	-1.9	-2.4	-2.5	-2.6	2.6	2.2	2.0	2.4	2.5	2.6	1.7	2.4
Impedance of arm (right)	4.5	21.0	36.0	5.5	5.4	4.7	4.0	4.6	4.6	6.0	4.7	5.2	-3.1	5.8	0.7	4.2	4.7	4.3	4.8	-4.5	-4.2	-4.4	-4.8	-4.4	-4.5	-3.7	-4.6
Alcohol intake versus 10 years previously	4.5	6.8	12.1	-2.7	-3.5	-2.6	-3.0	-2.6	-2.5	-2.6	-2.7	-1.9	0.4	-3.5	1.4	-2.8	-2.8	-2.4	-2.5	2.5	2.3	2.9	3.0	2.5	2.5	2.7	2.5
Forced expiratory volume in 1-second (FEV1), Best measure	4.4	14.1	24.4	-4.4	-3.4	-3.4	-3.9	-4.2	-3.4	-2.7	-3.7	-3.3	1.7	-3.3	-0.6	-4.0	-3.5	-4.0	-4.4	3.8	4.9	4.9	3.8	3.6	4.0	3.3	4.9
Migraine (self-reported)	4.4	5.4	10.9	-1.5	-3.3	-2.7	-2.6	-2.4	-2.5	-2.6	-2.5	-2.5	0.0	-3.3	-0.8	-1.6	-1.7	-2.4	-2.6	2.6	1.7	1.9	2.8	2.7	2.6	1.7	2.0
Intelligence (Savage-Jansen 2018)	4.3	13.2	24.6	-5.0	-3.5	-4.2	-3.3	-4.1	-4.2	-4.4	-4.2	-4.5	2.5	-3.2	0.5	-3.2	-2.1	-3.7	-4.3	3.8	3.5	2.9	3.7	3.6	3.5	2.7	3.6
Forced vital capacity (FVC)	4.3	16.4	28.0	-4.3	-3.7	-3.6	-4.4	-4.4	-3.7	-3.0	-4.0	-3.6	1.4	-3.6	-1.6	-5.0	-3.8	-4.2	-4.5	3.9	5.1	4.9	4.1	3.8	4.3	4.7	5.3
Qualifications: A levels/AS levels or equivalent	4.2	9.2	18.0	-3.5	-1.9	-2.8	-2.7	-3.1	-3.0	-2.9	-2.8	-2.9	4.2	-1.8	-1.6	-3.9	-1.2	-3.2	-3.2	2.8	3.9	3.5	2.8	2.7	3.0	3.4	3.9
Prospective memory result	4.1	5.1	9.0	1.2	2.0	2.5	2.2	2.5	2.3	2.2	2.2	2.3	-0.6	1.5	2.4	2.2	-0.1	2.9	2.7	-2.8	-2.2	-2.0	-2.6	-2.8	-3.0	-2.1	-2.4
Relative age of first facial hair	4.0	8.2	16.6	3.1	2.1	2.9	2.5	3.1	2.9	2.5	3.0	1.8	-2.9	1.9	0.4	3.9	0.3	3.2	2.7	-3.0	-3.3	-3.0	-3.1	-3.0	-3.3	-4.1	-3.5
Qualifications: O levels/GCSEs or equivalent	3.9	6.2	12.0	-2.9	-2.3	-2.3	-2.7	-2.2	-2.0	-2.6	-2.1	-2.8	2.3	-2.5	-2.1	-3.5	-2.2	-2.1	-2.4	2.0	2.6	2.5	2.2	1.9	2.3	3.4	2.7
Mean time to correctly identify matches	3.9	7.4	12.5	3.5	2.8	3.2	3.0	3.0	3.1	2.7	3.3	2.6	-0.6	2.9	1.3	1.9	3.4	2.6	2.8	-2.8	-2.5	-2.6	-3.0	-2.8	-2.5	-1.5	-2.6
Qualifications: None of the above	3.8	8.1	13.5	3.5	2.0	2.9	3.0	2.9	3.4	3.1	3.0	3.5	-2.2	1.7	1.1	3.7	1.7	2.8	3.1	-2.7	-3.4	-2.5	-2.7	-2.6	-2.7	-3.3	-3.3
Impedance of arm (left)	3.8	17.7	32.2	5.1	5.0	4.4	3.7	4.0	4.4	5.7	4.4	4.8	-3.0	5.3	0.8	4.1	4.2	3.8	4.2	-3.9	-3.7	-3.9	-4.4	-3.9	-3.9	-3.9	-4.2
Whole body fat mass	3.6	14.8	27.6	-5.3	-4.1	-3.5	-2.8	-3.6	-3.3	-3.9	-3.4	-4.1	4.4	-4.1	0.1	-4.8	-1.6	-3.7	-3.9	3.4	4.5	4.4	3.8	3.2	3.7	4.5	4.8
Average weekly beer plus cider intake	3.6	5.2	9.2	2.4	1.4	2.7	2.7	2.4	2.7	3.0	2.7	2.5	-1.7	1.2	0.2	2.5	0.6	2.4	2.7	-2.3	-2.4	-2.3	-2.3	-2.3	-2.2	-2.5	-2.2
Reaction Time	3.5	6.7	11.4	3.4	2.8	3.0	2.6	2.7	2.8	2.8	3.3	2.3	-1.1	2.6	2.0	1.8	3.3	2.4	2.7	-2.6	-2.5	-2.7	-2.9	-2.6	-2.2	-1.4	-2.5
Pulse rate	3.5	6.0	10.6	2.7	1.4	2.6	1.7	2.7	3.1	3.3	2.4	2.8	-1.8	0.7	1.0	2.9	-0.2	2.8	2.9	-2.6	-3.0	-2.5	-2.3	-2.5	-2.6	-2.4	-2.8
Systolic Blood Pressure	3.4	17.1	34.1	-3.1	-3.4	-3.8	-4.1	-4.4	-3.9	-4.4	-3.9	-2.8	2.5	-3.2	-0.9	-5.7	-2.1	-4.7	-4.1	4.2	5.1	4.9	4.3	4.2	4.7	5.8	5.2
Chronic bronchitis/emphysema (father)	3.4	4.0	6.9	1.7	1.9	2.2	2.5	2.3	2.2	1.8	1.9	2.1	-0.6	1.7	0.9	1.6	1.2	2.5	2.3	-2.6	-2.0	-2.0	-2.2	-2.6	-2.5	-1.1	-1.9
Waist circumference	3.4	12.4	23.2	-4.8	-4.2	-3.5	-2.9	-3.5	-3.4	-3.6	-3.4	-4.2	2.8	-4.4	0.6	-4.1	-2.6	-3.3	-3.5	3.2	3.3	3.3	3.6	3.1	3.4	3.9	3.8
Leg fat percentage (right)	3.4	12.3	26.3	2.9	1.9	3.0	4.9	3.9	2.8	3.1	3.4	1.9	-2.1	1.7	1.2	4.6	3.6	3.7	3.9	-3.4	-5.1	-4.8	-3.1	-3.3	-3.6	-3.9	-4.6
Verbal and Numeric Reasoning (VNR)	3.2	7.7	17.9	-4.2	-2.9	-3.1	-2.3	-3.0	-3.0	-3.2	-3.2	-3.4	2.5	-2.6	0.2	-2.3	-1.6	-2.8	-3.2	2.9	2.7	2.4	2.8	2.7	2.7	2.0	2.8
Waist Hip Ratio (WHR)	3.2	14.2	34.3	3.7	2.2	2.9	2.8	3.3	3.1	3.8	3.0	2.2	-5.9	2.2	2.9	5.3	0.2	3.7	3.1	-3.1	-5.8	-5.3	-3.3	-2.7	-3.6	-4.8	-5.7
Qualifications: College or University degree	3.2	10.2	17.0	-4.1	-1.8	-2.9	-3.4	-3.6	-3.3	-3.7	-3.2	-3.2	3.7	-1.5	-1.6	-3.7	-1.6	-3.4	-3.7	3.2	4.1	3.4	2.7	3.1	3.1	3.1	3.7
Supplements: Zinc	3.1	3.3	8.5	-1.8	-1.4	-1.9	-1.8	-1.8	-1.7	-2.5	-2.0	-0.9	1.3	-1.8	-0.3	-2.6	-1.5	-1.8	-1.5	1.7	1.8	1.8	2.0	1.8	1.7	2.9	1.8
Average weekly champagne plus white wine intake	3.1	4.2	7.3	-1.2	-1.9	-2.2	-1.7	-2.0	-2.1	-2.0	-2.3	-2.3	1.0	-1.9	-0.2	-2.1	-1.8	-2.3	-2.2	2.4	2.5	2.3	2.4	2.2	2.4	1.8	2.7
Prostate Cancer	3.0	4.3	9.2	1.9	1.4	1.9	1.8	2.0	1.8	1.9	1.9	1.0	-2.7	1.5	0.5	3.0	0.7	2.2	1.7	-2.1	-2.6	-2.6	-2.1	-2.1	-2.3	-3.0	-2.5
Medication: Metformin	3.0	4.3	8.4	-1.9	-2.4	-2.3	-2.4	-2.2	-2.3	-2.9	-2.4	-2.5	0.3	-2.2	-0.3	-2.0	-1.2	-2.0	-2.2	2.1	2.0	1.9	2.2	2.0	1.9	1.6	2.1
Arm fat mass (left)	3.0	12.2	24.5	-5.0	-4.0	-3.2	-2.4	-3.2	-3.1	-3.7	-3.1	-4.0	3.9	-4.1	0.6	-4.3	-1.7	-3.1	-3.4	2.9	3.8	3.8	3.5	2.7	3.2	4.0	4.3
Mouth/teeth dental problems	2.9	4.4	7.2	-2.0	-2.2	-2.1	-2.2	-2.1	-2.2	-2.4	-2.3	-2.6	-0.5	-1.9	-0.2	-1.8	-2.7	-2.1	-2.2	2.3	2.1	2.3	2.2	2.3	2.2	1.4	2.0
Asthma	2.9	5.7	8.7	-2.5	-2.7	-2.5	-2.4	-2.6	-2.0	-2.2	-2.6	-2.1	0.6	-2.9	-1.2	-2.5	-2.7	-2.4	-2.6	2.5	2.0	1.8	2.7	2.6	2.6	2.7	2.3
Length of working week for main job	2.8	3.1	5.7	-2.1	-1.7	-1.8	-1.9	-2.0	-1.8	-2.4	-1.6	-2.3	1.4	-1.7	0.1	-1.9	-1.1	-1.7	-2.3	1.8	1.8	1.7	1.6	1.7	1.7	1.4	1.6
Chest pain or discomfort	2.8	4.1	7.3	-2.6	-2.7	-2.5	-1.8	-2.1	-1.9	-1.8	-2.4	-1.5	2.2	-2.4	0.1	-1.9	-1.0	-1.9	-2.1	2.0	1.5	1.7	2.4	2.1	2.0	2.4	1.8
Back pain experienced in last month	2.7	3.9	8.5	1.5	2.2	2.2	1.7	2.2	2.0	2.9	1.9	2.6	0.3	2.4	-0.3	1.8	0.9	2.3	2.3	-2.3	-1.1	-0.8	-2.1	-2.5	-2.4	-2.2	-1.4
HDL Cholesterol	2.6	4.3	16.3	4.0	2.2	2.0	1.8	2.0	2.5	1.9	2.1	2.7	-1.4	2.3	0.3	2.1	1.9	1.9	2.1	-1.9	-1.7	-1.4	-2.0	-1.8	-1.8	-1.7	-1.9
Ulcerative Colitis	2.6	3.8	10.1	-3.2	-2.0	-1.7	-2.0	-2.0	-1.5	-2.0	-1.9	-1.3	1.9	-2.2	-1.0	-2.2	-1.8	-1.7	-2.0	1.6	2.2	2.5	1.8	1.6	1.6	2.0	2.1
Number of incorrect matches in round	2.6	4.3	7.5	2.6	2.2	2.7	2.4	2.0	2.2	2.7	2.6	2.5	-1.8	2.4	-0.5	1.9	1.7	1.8	2.1	-1.9	-1.5	-1.5	-2.2	-1.9	-1.7	-2.0	-1.7
High blood pressure (siblings)	2.6	3.7	7.9	-1.7	-2.7	-2.3	-1.2	-1.8	-2.8	-2.2	-2.4	-2.5	0.4	-2.6	-0.7	-1.2	-1.9	-1.7	-1.5	2.0	1.3	1.3	2.4	1.9	2.0	1.1	1.9
Asthma (self-reported)	2.6	5.2	8.7	-2.4	-2.6	-2.4	-2.2	-2.4	-2.0	-2.1	-2.5	-2.0	0.1	-3.0	-1.3	-2.4	-2.7	-2.2	-2.4	2.4	1.9	1.7	2.6	2.5	2.4	2.7	2.2
Leg fat percentage (left)	2.6	9.4	22.8	2.4	1.2	2.5	4.3	3.4	2.5	2.8	3.0	1.7	-1.9	1.0	1.0	4.2	2.9	3.3	3.4	-2.9	-4.8	-4.4	-2.6	-2.8	-3.0	-3.4	-4.1
Triglycerides	2.5	4.1	8.7	1.7	2.9	2.4	1.9	2.1	2.0	1.5	2.3	1.1	-1.1	2.8	-0.2	1.3	2.2	2.0	1.9	-2.2	-1.8	-2.5	-2.5	-2.3	-2.2	-1.3	-2.0
Lung FEV1/FVC ratio	2.5	12.8	24.7	-5.0	-3.2	-3.4	-3.1	-3.9	-3.7	-3.0	-3.9	-3.1	1.7	-2.9	-0.1	-3.2	-3.8	-3.7	-4.0	3.8	4.6	4.6	3.8	3.5	3.7	2.3	4.6
Sensitivity / hurt feelings	2.5	4.2	7.7	1.3	1.4	2.3	2.3	2.3	2.3	2.8	2.3	1.7	-1.3	1.1	1.2	2.4	0.3	2.4	2.2	-2.2	-2.4	-2.0	-2.2	-2.2	-2.1	-2.3	-2.3
Diabetes (self-reported)	2.5	3.9	7.0	-2.3	-2.0	-2.4	-2.0	-2.0	-2.5	-2.6	-2.4	-2.6	0.6	-1.8	0.1	-2.1	-0.8	-1.8	-2.2	1.9	2.0	1.6	2.1	1.7	1.7	1.8	2.1
Arm fat mass (right)	2.5	10.5	22.3	-4.7	-3.7	-2.9	-2.1	-2.8	-2.9	-3.4	-2.8	-3.7	3.9	-3.8	0.4	-4.1	-1.2	-2.8	-3.1	2.6	3.5	3.5	3.2	2.4	2.9	4.0	4.0
Age at last live birth	2.5	3.6	5.7	-1.7	-1.5	-2.0	-2.0	-2.1	-1.9	-2.1	-2.0	-1.4	2.4	-1.4	-1.5	-2.0	-1.0	-2.0	-1.9	2.0	2.2	2.1	2.0	1.9	2.0	1.8	2.2
Respiratory disease	2.4	5.3	13.4	-3.2	-2.8	-2.2	-2.2	-2.2	-2.1	-2.2	-2.5	-2.2	0.0	-3.3	-1.6	-2.0	-3.7	-1.9	-2.3	2.2	1.8	2.0	2.4	2.2	2.0	1.8	2.2
Other serious medical condition/disability diagnosed by doctor	2.4	3.1	6.1	0.1	0.4	2.0	1.7	2.1	1.6	2.4	1.9	1.1	-1.8	-0.1	0.3	1.8	-1.2	2.3	2.1	-2.4	-2.0	-1.3	-1.8	-2.5	-2.2	-1.7	-1.6
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	4.2	-1.4	-1.9	-2.1	-1.8	-1.9	-1.6	-1.8	-2.0	-2.0	0.1	-1.6	0.1	-1.4	-1.2	-1.7	-2.0	1.8	1.2	1.1	1.9	1.9	1.7	1.4	1.3
High blood pressure (mother)	2.4	3.4	8.5	-1.1	-1.8	-1.5	-1.3	-1.7	-1.3	-1.5	-1.4	-1.4	2.9	-1.9	0.2	-2.1	-1.6	-2.0	-1.6	2.0	2.3	2.3	2.0	1.9	2.3	2.0	2.5
Commuting to job workplace: Cycle	2.3	2.8	7.1	-1.1	-0.5	-1.4	-2.3	-2.1	-1.7	-1.3	-1.4	-1.0	1.1	-0.6	0.1	-2.1	-0.1	-2.1	-1.8	1.9	2.6	2.7	1.4	1.8	2.0	1.4	2.2
Wheeze or whistling in the chest in last year	2.2	3.9	7.8	-2.1	-2.5	-2.1	-2.0	-2.1	-1.9	-2.1	-2.1	-1.4	0.4	-2.5	0.9	-2.1	-2.8	-1.9	-2.1	1.8	1.5	1.7	2.2	2.0	1.9	2.3	1.6
Number of full sisters	2.2	2.6	5.6	1.1	0.9	1.7	2.0	1.9	1.2	1.6	1.7	0.5	-0.6	0.5	0.8	1.8	0.5	2.1	2.0	-2.0	-2.4	-2.0	-1.7	-1.9	-1.9	-1.6	-2.1
Pain experienced in last month	2.2	3.8	6.4	-1.4	-1.4	-1.7	-1.8	-2.4	-1.0	-2.1	-1.8	-1.1	1.9	-1.3	0.0	-2.2	-0.7	-2.4	-2.4	2.3	2.4	2.4	1.9	2.4	2.5	2.3	2.2
Schizophrenia vs Biploar Disorder	2.1	2.8	4.8	0.8	1.7	2.1	1.7	1.7	2.0	1.9	1.9	1.6	-1.3	1.3	0.0	2.1	0.3	1.8	1.6	-1.8	-1.6	-1.5	-1.9	-1.9	-1.9	-2.2	-1.6
Systolic blood pressure, automated reading	2.1	6.1	12.6	-2.4	-1.9	-2.4	-2.0	-2.6	-2.2	-2.4	-2.5	-1.1	1.8	-1.6	-1.0	-3.2	-0.9	-3.0	-2.3	2.7	3.0	3.0	2.7	2.7	2.9	3.5	3.1
Medication: Ventolin 100micrograms inhaler	2.1	2.7	6.4	-2.2	-1.9	-1.5	-1.4	-2.0	-1.6	-1.4	-1.5	-1.2	-0.3	-2.3	0.1	-2.0	-2.3	-1.5	-1.8	1.5	1.1	0.8	1.6	1.7	1.6	2.5	1.3
Chronic bronchitis/emphysema (mother)	2.1	2.5	7.8	1.6	1.5	1.3	1.4	1.1	1.2	2.1	1.3	2.0	-0.7	1.5	2.8	2.1	1.2	1.3	1.6	-1.1	-1.5	-1.3	-1.4	-1.1	-1.2	-2.3	-1.6
Medication: Blood pressure	2.1	4.0	6.8	-1.6	-2.6	-2.4	-1.2	-2.1	-1.7	-2.4	-2.2	-2.1	0.3	-2.5	0.4	-1.9	-1.1	-2.2	-2.3	2.1	1.6	1.5	2.3	2.2	2.3	2.4	2.0
High cholesterol (Self-reported)	2.1	3.8	7.8	2.3	2.4	1.7	2.5	1.7	1.7	1.8	1.7	2.2	-1.2	2.7	0.9	1.6	2.8	1.5	1.9	-1.7	-2.1	-2.5	-1.8	-1.5	-1.7	-0.9	-2.2
Alzheimer’s Disease (in father)	2.0	2.1	6.9	2.2	1.0	1.7	1.9	1.7	1.1	1.3	1.4	0.7	-2.6	1.0	0.7	1.7	0.1	1.3	1.5	-1.2	-1.4	-1.2	-1.3	-1.4	-1.3	-1.9	-1.3
Had menopause	2.0	2.6	5.2	-2.3	-1.9	-1.7	-1.1	-1.7	-1.0	-1.3	-1.7	-0.2	1.4	-1.8	-0.8	-1.5	-1.5	-1.6	-1.5	1.4	1.7	2.2	1.8	1.5	1.6	2.0	1.8
Average weekly red wine intake	2.0	3.0	6.4	-2.2	0.1	-1.4	-1.4	-2.0	-1.5	-1.6	-1.4	-1.1	1.3	0.2	-2.5	-2.4	0.4	-1.9	-1.9	1.6	2.4	2.2	1.2	1.6	1.8	2.3	2.1
Diabetes diagnosed by doctor	2.0	3.2	5.5	-2.1	-2.0	-2.0	-1.8	-1.9	-2.1	-2.2	-2.1	-2.4	0.8	-1.9	0.7	-1.7	-1.2	-1.7	-2.0	1.8	1.6	1.4	1.9	1.6	1.6	1.5	1.8
Chronotype (morning person)	1.9	4.5	10.1	-2.6	-2.2	-1.7	-2.4	-2.1	-1.3	-2.0	-1.9	-1.6	-0.2	-2.1	1.6	-2.5	-3.2	-2.1	-2.3	1.9	2.3	2.4	2.1	2.0	2.1	2.6	2.2
Unable to work because of sickness or disability	1.9	2.5	5.4	1.2	0.7	1.6	1.7	1.8	1.6	2.1	1.9	1.6	0.3	0.1	2.3	1.6	0.4	1.8	2.1	-1.9	-1.7	-1.1	-1.4	-1.9	-1.8	-1.6	-1.4
Depression (Nagel 2018)	1.8	2.7	5.8	-2.4	-1.6	-2.1	-1.5	-1.8	-2.1	-1.6	-1.9	-1.7	1.0	-1.5	0.5	-1.8	0.1	-1.6	-1.8	1.5	1.5	1.4	1.7	1.5	1.5	1.8	1.6
Diabetes (mother)	1.8	2.3	7.3	-2.0	-1.6	-1.3	-0.9	-1.2	-1.1	-1.5	-1.4	-1.0	1.7	-1.8	0.6	-2.4	-0.4	-1.4	-1.1	1.2	1.6	1.6	1.7	1.2	1.4	2.7	1.8
Number of live births	1.8	2.5	4.6	1.9	0.8	2.0	1.4	1.8	1.8	1.8	2.2	2.0	-0.6	1.2	-0.6	1.2	1.3	1.8	2.0	-1.8	-1.6	-1.0	-1.7	-1.9	-1.6	-1.2	-1.5
Commuting to job workplace: Car/motor vehicle	1.8	2.0	3.7	0.3	0.6	1.6	1.9	1.8	1.9	1.1	1.7	1.0	-0.3	0.7	-1.1	1.2	1.3	1.8	1.4	-1.8	-1.6	-1.5	-1.6	-1.9	-1.7	-1.0	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.9	10.3	1.3	1.7	1.7	2.0	1.4	1.6	3.0	1.7	1.6	-2.5	1.9	0.9	3.2	1.2	1.4	1.3	-1.4	-2.4	-2.5	-1.8	-1.3	-1.6	-3.0	-2.4
Tinnitus: Yes, now most or all of the time	1.8	2.1	4.6	-2.1	-1.3	-1.3	-1.6	-1.7	-1.1	-1.2	-1.3	-1.4	0.5	-1.1	0.8	-1.5	-0.9	-1.8	-2.0	1.6	1.5	1.4	1.4	1.6	1.6	1.4	1.4
Deep venous thrombosis (DVT) (self-reported)	1.8	2.4	12.2	-2.3	-1.6	-0.5	-1.2	-1.2	-0.2	-1.5	-1.2	-1.3	0.4	-1.8	-0.1	-1.3	-3.5	-1.1	-2.1	1.1	1.9	2.1	1.2	1.1	1.1	0.8	1.9
Coronary Artery Disease (CAD)	1.7	2.0	7.4	-2.7	-1.3	-1.4	-0.5	-1.0	-1.8	-1.3	-1.1	-1.8	1.5	-2.2	2.3	-1.4	-0.3	-0.7	-0.6	1.1	1.3	1.6	1.3	0.8	1.0	0.9	1.5
Blood clot in the leg (DVT)	1.7	2.2	11.4	-2.1	-1.6	-0.5	-1.1	-1.2	-0.2	-1.5	-1.2	-1.2	-0.0	-1.8	-0.0	-1.2	-3.4	-1.1	-2.0	1.1	1.8	2.0	1.2	1.0	1.1	0.8	1.7
Ever taken oral contraceptive pill	1.7	1.9	3.0	1.4	1.7	1.6	1.4	1.4	1.5	1.6	1.7	0.8	-0.4	1.5	-1.6	1.4	0.9	1.2	1.1	-1.3	-1.4	-1.7	-1.6	-1.3	-1.2	-1.5	-1.5
Eye problems/disorders: Glaucoma	1.7	2.0	4.8	2.0	1.8	1.3	0.9	1.3	0.9	1.2	1.4	1.1	-1.0	1.8	-1.3	1.6	2.2	1.2	1.3	-1.2	-1.3	-1.4	-1.6	-1.2	-1.2	-1.8	-1.6
Illnesses of siblings	1.6	2.2	7.2	1.3	2.7	1.5	0.6	1.0	2.1	1.1	1.5	2.2	0.6	2.4	1.2	0.9	1.9	1.2	1.0	-1.4	-0.6	-0.8	-1.8	-1.3	-1.5	-1.2	-1.3
Hair/balding pattern: Pattern 3	1.6	2.4	5.7	-1.6	-0.8	-1.3	-0.7	-1.5	-1.5	-1.7	-1.6	-0.8	2.4	-0.7	-0.0	-2.2	-1.2	-1.5	-1.4	1.4	2.2	1.7	1.5	1.2	1.4	2.1	2.2
Loud music exposure frequency	1.6	1.8	4.4	0.5	0.9	1.6	1.3	1.3	1.9	2.1	1.7	1.7	-0.6	1.1	0.4	0.8	0.9	1.3	1.2	-1.6	-1.6	-1.2	-1.5	-1.4	-1.3	-0.2	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	2.0	3.7	1.1	1.6	1.4	1.2	1.6	1.4	1.0	1.2	1.6	0.1	1.5	-0.6	1.1	1.3	1.8	1.5	-1.9	-1.5	-1.3	-1.7	-1.9	-1.8	-0.7	-1.5
Leg fat mass (left)	1.6	6.2	13.5	-3.7	-3.2	-2.4	-1.3	-2.1	-2.3	-2.8	-2.2	-3.2	3.0	-3.3	0.1	-2.8	-0.8	-2.1	-2.3	2.1	2.3	2.3	2.6	1.9	2.3	2.7	2.8
Noisy workplace	1.5	1.8	3.7	0.8	0.7	1.8	1.3	1.5	1.5	1.9	1.8	1.6	-1.6	0.4	0.2	1.4	-0.4	1.4	1.6	-1.4	-1.3	-1.0	-1.4	-1.4	-1.3	-1.4	-1.2
Headache pain in last month	1.5	2.6	5.0	-1.2	-1.2	-1.9	-1.8	-1.9	-2.2	-1.8	-1.9	-2.1	0.3	-1.4	1.4	-0.8	-1.5	-1.8	-2.1	2.0	1.5	1.3	1.7	1.9	1.7	0.4	1.4
Osteoarthritis (self-reported)	1.5	2.0	4.5	1.2	0.7	1.2	1.5	1.3	1.4	1.9	1.6	1.3	-1.1	1.0	1.5	1.9	2.1	1.1	1.2	-1.0	-1.7	-1.8	-1.2	-1.1	-1.0	-1.8	-1.5
Medication: Bendroflumethiazide	1.5	2.3	4.2	-0.6	-2.0	-1.6	-1.0	-1.5	-1.4	-1.6	-1.8	-1.9	0.2	-1.8	2.0	-1.2	-1.7	-1.5	-1.5	1.5	1.0	1.0	1.7	1.6	1.7	1.6	1.4
Blood Platelet Count	1.4	15.7	25.6	-4.7	-5.1	-4.5	-3.4	-4.4	-4.2	-4.2	-4.6	-3.3	0.7	-5.0	3.3	-2.5	-4.1	-4.0	-4.2	4.5	2.8	3.6	4.7	4.7	4.2	2.5	3.1
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	3.1	-0.0	-1.0	-1.6	-1.3	-1.4	-1.1	-1.1	-1.6	-0.7	0.8	-0.8	0.3	-0.8	-0.5	-1.7	-1.3	1.7	1.4	1.4	1.6	1.8	1.6	0.9	1.3
Pulse wave reflection index	1.4	1.8	3.4	-1.7	-1.0	-1.1	-0.5	-1.3	-1.6	-1.8	-1.2	-1.5	1.1	-0.8	1.8	-1.7	-0.8	-1.2	-1.3	1.3	1.5	1.4	1.2	1.2	1.3	1.2	1.4
Medication: Aspirin	1.4	1.9	8.0	1.2	1.3	1.0	1.9	1.6	0.6	0.9	1.0	0.5	0.4	1.3	1.1	1.1	2.8	1.3	1.5	-1.4	-1.6	-1.8	-1.2	-1.4	-1.4	-0.8	-1.4
Medication: Gliclazide	1.4	1.5	4.7	-1.6	-1.2	-1.1	-1.3	-0.9	-1.6	-1.9	-1.2	-2.2	0.7	-1.0	-1.3	-1.7	-0.6	-0.8	-1.1	0.9	1.3	1.1	1.0	0.7	0.9	1.3	1.4
Medication: Atorvastatin	1.4	1.7	3.6	0.8	0.8	1.2	1.9	1.6	1.2	1.2	1.0	1.2	-1.2	0.6	1.6	1.4	0.4	1.4	1.4	-1.5	-1.5	-1.4	-1.1	-1.5	-1.7	-1.1	-1.4
Alcohol drinker status: Never	1.4	1.6	2.6	1.1	0.9	1.6	1.4	1.4	1.1	1.3	1.4	0.8	-1.4	0.7	0.9	1.1	0.2	1.5	1.2	-1.5	-1.6	-1.6	-1.4	-1.4	-1.5	-1.0	-1.6
Diabetes (father)	1.3	1.6	4.2	-1.2	-1.0	-0.6	-1.1	-1.1	-0.9	-1.7	-0.5	-1.6	1.4	-1.2	1.8	-2.0	-0.6	-0.9	-1.1	1.0	1.5	1.2	0.8	0.8	1.2	1.6	1.4
Townsend deprivation index at recruitment	1.3	1.9	4.2	1.6	-0.5	1.0	0.6	1.4	1.1	1.4	1.3	0.6	-1.8	-0.5	0.4	2.0	-1.1	1.7	1.5	-1.3	-1.9	-1.3	-1.1	-1.3	-1.3	-2.0	-1.7
Tinnitus: Yes, but not now, but have in the past	1.3	1.3	2.2	0.6	1.2	1.3	1.1	1.4	1.3	1.5	1.3	1.1	0.2	1.4	0.1	1.0	0.7	1.4	1.2	-1.3	-0.9	-0.6	-1.4	-1.3	-1.4	-1.3	-1.3
Medication: Cholesterol lowering	1.3	2.0	4.6	1.6	1.9	1.4	1.5	1.5	1.2	1.6	1.5	1.3	0.1	2.1	0.8	0.9	1.7	1.3	1.5	-1.5	-1.2	-1.3	-1.6	-1.5	-1.5	-1.0	-1.3
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	3.7	1.5	1.0	1.3	1.7	1.5	1.0	1.5	1.6	0.3	-0.3	0.7	-0.5	1.3	1.9	1.2	1.2	-1.4	-1.8	-1.9	-1.3	-1.4	-1.2	-1.0	-1.5
Medication: Seretide 50 evohaler	1.3	1.5	3.6	-0.7	-1.4	-1.2	-1.3	-1.3	-0.6	-1.1	-1.3	-0.5	0.3	-1.7	0.7	-1.3	-1.9	-1.3	-1.2	1.4	0.9	0.8	1.4	1.5	1.4	1.9	1.0
Illnesses of siblings: Diabetes	1.3	1.6	5.8	-2.0	-2.4	-1.1	-0.4	-0.7	-1.4	-1.2	-1.1	-1.8	-0.4	-2.2	-1.1	-1.2	-2.1	-0.5	-0.5	0.5	0.2	0.3	1.2	0.5	0.7	1.7	0.9
Guilty feelings	1.3	2.0	7.0	-1.0	-2.4	-1.5	-1.5	-1.2	-1.4	-1.0	-1.6	-1.7	-0.7	-2.3	-0.8	-0.7	-2.6	-1.0	-1.4	1.2	0.6	1.1	1.5	1.3	1.3	0.8	1.0
Commuting to job workplace: Public transport	1.3	1.5	3.1	-1.3	-0.9	-1.2	-1.6	-1.6	-0.9	-1.4	-1.3	-1.0	-0.3	-0.9	-0.3	-1.3	-1.8	-1.4	-1.7	1.4	1.2	0.9	1.1	1.4	1.2	1.3	1.0
Alzheimer’s Disease (including proxy)	1.2	1.8	5.2	2.3	1.1	1.4	1.9	1.4	0.9	1.6	1.2	1.2	-2.2	1.3	0.1	1.5	0.4	0.9	1.3	-1.0	-1.4	-1.3	-1.0	-1.0	-1.0	-1.1	-1.3
Ulcerative Colitis (UC)	1.2	2.2	8.0	-2.8	-1.5	-1.2	-1.1	-1.6	-1.1	-1.2	-1.4	-0.8	1.7	-1.7	-1.0	-1.4	-2.0	-1.3	-1.5	1.3	1.6	1.7	1.4	1.3	1.3	1.2	1.6
Multivitamins +/- minerals	1.2	1.6	3.9	-2.0	-1.2	-0.9	-0.8	-1.0	-0.7	-1.1	-1.2	0.0	0.5	-1.5	1.9	-1.4	-1.2	-1.2	-1.0	1.0	1.3	1.8	1.3	1.1	1.0	1.6	1.3
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	2.7	0.9	0.2	1.4	1.6	1.6	0.9	1.6	1.4	0.1	-0.6	-0.0	0.0	1.5	-0.1	1.5	1.3	-1.3	-1.6	-1.4	-1.1	-1.4	-1.2	-1.4	-1.2
Medication: Atenolol	1.2	1.5	3.7	-1.6	-0.6	-1.4	-1.1	-1.1	-1.1	-1.9	-1.2	-1.6	1.5	-0.7	1.5	-1.6	-0.4	-1.0	-1.3	0.9	0.9	0.8	1.0	1.0	1.0	1.6	0.9
Ever had prostate specific antigen (PSA) test	1.2	1.4	2.9	-1.2	-0.2	-1.3	-0.9	-1.4	-1.4	-0.7	-1.2	-0.6	0.9	-0.2	-0.8	-1.3	-0.0	-1.7	-1.4	1.6	1.4	1.0	1.2	1.6	1.6	1.2	1.3
Alcohol drinker status: Previous	1.2	1.4	3.3	-0.2	-1.1	-1.2	-0.9	-1.1	-0.4	-0.7	-1.3	0.5	1.6	-1.2	0.4	-1.2	-1.5	-1.2	-0.8	1.2	1.2	1.6	1.5	1.3	1.3	1.8	1.3
Maternal smoking around birth	1.1	1.6	5.5	1.0	-0.3	0.9	0.9	1.1	0.6	1.4	0.9	-0.1	-2.3	-0.4	2.1	1.9	-1.2	1.1	0.8	-0.8	-1.7	-1.2	-0.7	-0.9	-1.1	-2.3	-1.5
Medication: Simvastatin	1.1	1.6	7.0	1.8	2.2	1.1	1.2	0.7	1.3	1.1	1.0	1.5	-0.1	2.6	1.4	0.2	2.2	0.5	0.8	-0.7	-0.6	-1.1	-1.2	-0.6	-0.6	0.1	-1.0
Leg fat mass (right)	1.1	4.1	10.2	-3.2	-2.6	-1.9	-0.7	-1.6	-1.9	-2.4	-1.7	-2.9	2.7	-2.7	0.3	-2.3	-0.3	-1.6	-1.8	1.5	1.9	1.8	2.0	1.4	1.7	2.2	2.3
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	5.3	2.0	1.7	1.1	1.4	0.8	1.0	1.8	1.1	1.0	-0.7	1.8	0.5	1.6	2.3	0.5	0.7	-0.7	-1.5	-1.8	-1.2	-0.6	-0.7	-1.2	-1.4
Ever depressed for a whole week	1.1	1.4	3.6	0.6	0.9	1.8	1.3	1.4	1.7	1.8	1.9	1.1	0.0	0.6	0.0	0.6	0.7	1.3	1.2	-1.4	-1.0	-0.8	-1.4	-1.3	-1.0	-0.5	-1.0
Medication: Ramipril	1.0	1.2	6.9	-0.9	-0.6	-1.4	-0.9	-1.1	-1.2	-1.4	-1.4	-1.5	-0.0	-0.2	2.6	-1.1	0.1	-1.0	-1.2	0.9	0.8	0.5	0.9	0.9	0.8	1.1	0.8
Happiness	1.0	1.3	5.1	-1.2	-1.0	-1.5	-1.0	-1.1	-1.3	-1.1	-1.3	-0.5	1.3	-1.0	2.3	-1.0	1.3	-0.9	-1.0	0.9	0.7	0.8	1.1	1.0	0.8	1.2	0.7
Birth weight	1.0	2.1	7.1	-1.2	-1.1	-0.4	-0.8	-1.3	-0.7	-0.2	-0.9	-1.0	1.6	-0.9	0.9	-2.0	-2.6	-1.2	-1.4	1.0	2.6	2.2	1.1	0.7	1.2	1.5	2.7
Exposure to tobacco smoke outside home	1.0	1.4	3.9	-1.1	-1.8	-1.4	-1.1	-1.1	-1.6	-0.8	-1.3	-1.0	0.2	-2.0	1.2	-1.1	-1.4	-0.9	-0.9	1.0	0.7	1.0	1.5	1.0	1.0	1.1	1.0
Eye problems/disorders: Cataract	1.0	1.1	3.6	-1.0	-1.1	-1.3	-0.9	-0.9	-1.9	-1.4	-1.4	-1.2	1.4	-0.9	0.2	-0.8	-0.4	-0.9	-0.8	0.9	0.8	0.9	1.2	0.9	0.9	0.9	1.0
Ovarian Cancer	0.9	1.2	5.4	1.8	1.3	0.6	0.9	1.0	0.4	0.4	0.5	0.7	-2.1	1.9	-0.7	0.5	2.3	0.7	0.9	-0.8	-0.9	-1.0	-0.8	-0.7	-0.7	-0.2	-1.0
Neuroticism	0.9	2.3	6.5	-2.5	-2.1	-1.7	-1.0	-1.2	-1.8	-1.3	-1.7	-2.5	1.0	-2.3	0.1	-1.0	-1.2	-1.1	-1.7	1.3	1.0	1.0	1.6	1.2	1.2	0.9	1.3
Stomach or abdominal pain in last month	0.9	1.1	2.2	0.4	0.3	1.0	1.1	1.5	0.8	0.9	1.1	0.2	-0.3	0.2	-0.1	1.3	0.4	1.4	1.2	-1.3	-1.4	-1.3	-1.0	-1.5	-1.4	-1.3	-1.2
Hair/balding pattern: Pattern 2	0.9	1.1	2.9	0.5	0.4	0.8	1.0	0.8	1.4	1.6	1.2	1.0	-0.9	0.3	-1.5	1.7	1.1	0.7	0.7	-0.7	-1.3	-1.0	-0.9	-0.6	-0.6	-1.5	-1.2
Time employed in main current job	0.9	1.0	5.4	1.5	1.7	0.6	0.8	0.8	0.3	0.9	0.6	1.2	0.4	2.0	-0.8	0.3	2.3	0.6	1.0	-0.8	-0.2	-0.4	-0.8	-0.8	-0.7	-0.1	-0.3
Pulse rate, automated reading	0.9	2.9	7.8	2.6	0.7	2.1	1.1	1.5	2.6	2.8	2.1	2.3	-1.2	0.1	1.5	1.4	-0.7	1.4	1.7	-1.5	-1.8	-1.4	-1.5	-1.4	-1.2	-1.0	-1.7
Overall health rating	0.9	2.0	7.3	-0.3	-0.1	0.8	1.9	1.6	0.7	1.3	0.8	0.8	-0.5	-0.6	2.7	1.5	0.2	1.8	1.7	-1.7	-2.2	-1.9	-0.8	-1.6	-1.9	-1.0	-1.6
Illnesses of father: High blood pressure	0.9	1.2	4.6	-0.5	-1.4	-1.1	-0.6	-0.7	-1.7	-1.4	-1.0	-2.1	-0.3	-1.4	1.6	-1.0	-0.7	-0.9	-1.0	1.0	0.6	0.3	1.1	0.9	1.0	0.8	0.9
Irritability	0.9	1.6	4.0	-1.7	-1.0	-2.0	-1.5	-1.4	-1.9	-1.3	-1.6	-1.8	0.3	-0.8	0.7	-0.3	-0.2	-1.3	-1.5	1.5	0.7	0.8	1.3	1.5	1.2	-0.1	0.7
Pack years of smoking	0.9	1.3	3.0	-1.7	-1.6	-0.7	-0.9	-0.8	-0.6	-0.2	-0.9	-0.7	1.7	-1.5	1.4	-1.2	-1.3	-0.8	-0.9	0.8	1.1	1.5	1.2	0.7	0.9	1.2	1.3
Bipolar Disorder (2018)	0.8	1.3	3.1	-1.8	-1.4	-0.7	-0.6	-0.8	-1.1	-1.2	-0.5	-1.4	1.8	-1.7	0.0	-1.3	-0.5	-1.1	-0.9	0.8	1.1	1.0	0.9	0.7	1.2	1.3	1.4
Irritable Bowel Disease (IBD)	0.8	1.9	4.0	-2.0	-1.5	-1.3	-1.6	-1.3	-1.4	-1.6	-1.5	-1.0	0.9	-1.6	-0.9	-1.4	-1.9	-1.0	-1.2	1.1	1.3	1.6	1.4	1.1	1.0	1.3	1.4
Lupus	0.8	1.2	3.3	-1.0	0.1	-0.9	-1.3	-1.2	-0.8	-0.8	-1.0	-1.0	1.7	0.3	-0.9	-0.9	-0.5	-1.2	-1.4	1.3	1.8	1.6	0.7	1.2	1.1	0.1	1.3
Past tobacco smoking	0.8	1.5	6.5	-2.6	-0.3	-0.8	-0.5	-1.0	-0.9	-1.7	-0.9	-1.3	2.1	-0.2	-0.1	-1.7	0.6	-1.1	-1.3	0.7	1.4	1.0	0.7	0.7	0.8	1.7	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	6.9	-1.8	-1.3	-1.3	-0.8	-0.8	-1.0	-0.9	-1.1	-1.3	2.6	-1.4	-0.4	-1.0	0.4	-0.7	-1.0	0.6	0.6	0.4	0.9	0.6	0.6	1.2	0.8
Age at first live birth	0.8	1.4	4.2	-1.1	-0.4	-1.2	-1.1	-1.3	-1.5	-1.2	-1.2	-1.2	2.0	-0.3	-1.5	-1.2	-0.4	-1.3	-1.2	1.2	1.4	0.9	1.0	1.2	1.2	1.1	1.2
Health satisfaction	0.8	1.1	16.1	-1.5	-1.3	-0.7	0.3	-0.2	-0.6	-0.6	-0.9	-0.9	0.4	-1.4	4.0	0.0	-0.6	-0.0	-0.3	0.2	0.0	0.2	0.7	0.2	0.0	-0.0	0.4
Suffer from ‘nerves’	0.8	1.2	2.6	-1.3	-1.3	-1.6	-1.3	-1.4	-1.0	-0.8	-1.5	-0.8	-0.0	-1.1	0.2	-0.8	-0.5	-1.3	-1.3	1.2	0.6	0.9	1.4	1.4	1.2	1.3	0.8
Mood swings	0.8	1.4	5.4	-1.7	-2.1	-1.5	-1.4	-0.8	-1.5	-1.3	-1.3	-1.9	-0.2	-2.3	1.4	-0.4	-1.1	-0.4	-1.0	0.6	0.2	0.6	1.1	0.7	0.6	0.4	0.6
Osteoporosis (self-reported)	0.8	1.0	2.3	1.3	0.4	1.3	0.7	1.1	1.4	1.5	1.4	0.9	-0.4	0.0	-1.2	1.2	-0.2	1.0	1.1	-0.8	-0.7	-0.4	-1.0	-0.9	-0.7	-1.5	-0.7
Crohns Disease (2012)	0.7	1.2	3.3	-0.7	-0.9	-1.3	-1.8	-1.0	-1.3	-1.5	-1.3	-1.4	-0.6	-0.7	-1.2	-1.2	-0.7	-0.9	-0.9	0.9	1.0	0.9	1.0	0.9	0.9	1.1	1.0
Type 2 Diabetes (T2D) (2018)	0.7	1.4	3.6	-1.5	-1.2	-1.7	-1.8	-1.3	-1.5	-1.9	-1.6	-1.5	0.6	-0.9	-0.8	-0.8	-0.4	-1.0	-1.3	1.1	0.8	0.5	1.1	1.0	0.8	0.8	0.8
Vitamin and mineral supplements	0.7	0.9	2.3	1.4	1.3	0.8	0.8	0.7	0.9	0.2	1.0	-0.1	0.3	1.3	-0.4	0.9	1.4	0.8	0.5	-0.8	-0.9	-1.5	-1.2	-0.8	-0.8	-1.1	-1.1
Pack years adult smoking proportion	0.7	1.1	2.6	-1.6	-1.6	-0.7	-0.9	-0.7	-0.6	-0.1	-0.9	-0.7	1.4	-1.6	1.4	-0.9	-1.4	-0.7	-0.8	0.7	0.9	1.4	1.1	0.7	0.8	1.0	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.4	-1.4	-1.5	-1.3	-0.5	-0.9	-1.2	-0.5	-1.0	-1.4	0.7	-1.2	0.6	-0.9	-0.2	-0.9	-1.1	0.8	0.6	0.7	1.1	0.9	0.8	1.1	0.9
Allergy	0.7	1.5	3.9	2.0	0.9	1.2	1.2	1.3	0.9	1.3	1.5	1.0	-0.7	1.1	0.5	1.3	1.7	1.1	1.5	-1.2	-1.4	-1.1	-1.2	-1.3	-1.1	-1.2	-1.2
Arm fat percentage (right)	0.7	2.6	7.1	0.5	0.2	1.5	2.7	1.9	1.3	1.6	1.8	0.4	-0.4	0.1	1.5	1.6	2.0	1.8	1.8	-1.7	-2.4	-2.2	-1.3	-1.7	-1.7	-1.1	-1.9
Father’s age at death	0.7	0.9	1.9	0.2	-0.7	-1.0	-1.2	-0.8	-1.3	-1.1	-1.1	-0.5	-1.3	-0.6	0.0	-0.7	-1.4	-0.9	-0.6	1.2	1.2	1.2	1.1	1.1	1.0	0.4	1.1
Worrier / anxious feelings	0.7	1.3	3.2	-1.8	-1.6	-1.4	-1.2	-1.0	-1.1	-0.8	-1.6	-0.9	-0.7	-1.4	0.8	-0.6	-1.6	-0.9	-1.2	1.0	0.6	0.9	1.3	1.2	0.9	0.8	0.7
Illnesses of mother	0.7	0.9	3.2	-1.3	-1.2	-0.9	-1.7	-0.8	-0.9	-1.3	-1.1	-1.1	-0.8	-1.3	0.4	-0.6	-1.8	-0.4	-1.0	0.5	0.5	0.6	0.8	0.5	0.4	0.4	0.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	6.9	-1.1	-2.3	-0.6	-0.9	-0.5	-1.0	-1.0	-0.7	-0.7	0.1	-2.6	0.3	-1.1	-2.0	-0.3	-0.4	0.4	0.9	1.4	1.1	0.2	0.5	1.2	1.3
Shortness of breath walking on level ground	0.7	0.8	7.1	-0.4	-2.0	-0.2	-0.0	0.5	-0.2	-0.4	-0.2	-1.1	0.2	-2.1	2.7	-0.1	-1.4	0.5	0.2	-0.3	-0.5	0.3	0.4	-0.3	-0.3	0.2	-0.0
Emphysema/chronic bronchitis	0.7	0.8	4.3	0.8	-0.1	0.6	0.4	1.0	0.5	0.6	0.5	0.2	-2.1	0.2	0.3	1.0	-0.7	1.2	0.9	-0.9	-1.2	-0.8	-0.6	-0.8	-1.0	-1.0	-1.0
Angina (self-reported)	0.7	0.9	3.0	-1.5	-1.5	-1.3	-0.6	-0.6	-0.9	-1.2	-1.2	-0.7	0.9	-1.2	1.7	-0.8	-0.0	-0.6	-0.7	0.6	0.3	0.5	1.1	0.7	0.5	1.1	0.6
Family relationship satisfaction	0.7	0.9	2.8	-1.4	-0.8	-0.9	-0.7	-0.6	-1.5	-1.7	-0.9	-1.3	1.2	-0.8	1.0	-1.3	0.0	-0.3	-0.7	0.4	0.9	0.7	0.6	0.3	0.4	1.0	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.3	1.1	0.4	1.2	0.8	1.1	0.6	1.5	1.2	0.0	-0.8	0.8	0.7	0.5	0.2	1.1	1.2	-1.0	-1.0	-1.2	-1.0	-1.1	-0.9	-0.8	-0.9
Smoking status: Previous	0.7	1.1	4.9	2.2	0.5	0.7	0.4	0.9	0.9	1.3	0.7	1.2	-1.9	0.6	-0.0	1.5	-0.1	0.8	1.0	-0.5	-1.1	-0.9	-0.6	-0.5	-0.6	-1.5	-1.1
Number of operations (self-reported)	0.7	1.0	3.1	1.1	-0.5	0.7	1.3	1.2	0.5	1.2	0.8	0.0	0.0	-0.3	1.5	1.2	-0.3	1.1	1.0	-1.0	-1.8	-1.3	-0.6	-0.9	-0.9	-0.6	-1.3
Worry (Nagel 2018)	0.6	1.3	5.3	-2.3	-1.1	-1.4	-1.1	-1.3	-0.9	-0.4	-1.3	-0.7	0.3	-1.2	0.4	-0.8	-1.1	-1.4	-1.5	1.2	0.8	1.1	1.3	1.4	1.2	1.0	0.8
Neuroticism (2016)	0.6	0.9	2.4	-1.0	-1.6	-1.1	-1.0	-0.7	-0.8	-0.5	-0.9	-1.4	0.2	-1.5	0.0	-0.8	-0.7	-0.9	-0.8	0.8	0.5	0.7	1.0	0.9	1.0	1.2	0.8
Average weekly spirits intake	0.6	0.8	2.6	0.3	0.7	1.1	0.7	0.9	0.8	1.1	1.3	0.6	-1.6	0.7	-1.3	0.5	0.3	0.9	1.0	-1.0	-0.7	-0.5	-1.0	-1.0	-0.7	-0.6	-0.6
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.0	-1.2	-1.1	-1.3	-0.5	-0.8	-1.5	-0.9	-1.1	-1.2	-0.6	-1.1	1.7	-0.8	0.5	-0.5	-0.7	0.6	0.4	0.4	0.8	0.5	0.5	0.8	0.7
Serious illness, injury or assault to yourself	0.6	0.7	1.7	0.3	-0.1	0.4	0.7	1.1	0.3	0.6	0.5	0.1	0.5	-0.1	-1.1	1.0	0.0	1.3	1.0	-1.2	-1.2	-1.1	-0.6	-1.2	-1.3	-0.8	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	6.9	-2.6	-1.3	-1.0	-0.1	-0.5	-1.6	-0.8	-0.8	-1.6	1.4	-1.6	0.4	-0.7	0.2	-0.4	-0.7	0.2	0.3	0.2	0.7	0.1	0.2	0.9	0.7
Tense / ‘highly strung’	0.6	1.0	2.6	-1.4	-1.6	-1.3	-1.3	-1.0	-1.2	-0.3	-1.2	-1.0	0.3	-1.4	-0.0	-0.7	-0.6	-1.0	-1.0	1.0	0.4	1.0	1.2	1.1	0.9	0.8	0.6
Number of full brothers	0.6	0.7	2.9	0.1	0.7	1.2	0.2	0.6	1.2	1.0	0.9	1.0	-1.7	0.6	-0.6	0.9	-0.3	0.9	0.6	-0.8	-0.5	-0.2	-1.0	-0.8	-0.8	-1.3	-0.7
Pulse wave peak to peak time	0.6	0.7	2.6	-0.3	-0.6	-0.6	-1.1	-1.0	-1.0	-0.4	-0.6	-0.9	-0.1	-0.4	-1.6	-0.9	-0.6	-1.0	-0.9	0.9	1.0	0.8	0.7	0.8	1.0	0.7	1.1
Illnesses of father: Heart disease	0.6	0.8	6.4	-0.2	0.9	0.5	1.0	0.6	0.2	1.0	0.8	0.4	-0.1	1.0	-2.0	0.4	2.5	0.3	0.7	-0.5	-0.7	-1.1	-0.6	-0.6	-0.5	-0.1	-0.7
Arm fat percentage (left)	0.6	2.5	6.8	0.6	0.1	1.5	2.6	1.8	1.3	1.6	1.8	0.2	-0.5	-0.1	1.6	1.7	1.8	1.7	1.7	-1.6	-2.3	-2.2	-1.3	-1.7	-1.6	-1.4	-1.8
Medication: Aspirin	0.6	0.8	4.8	0.9	0.8	0.6	1.5	1.0	0.4	0.7	0.6	0.2	0.5	0.7	1.4	0.5	2.2	0.6	0.9	-0.7	-0.9	-1.1	-0.6	-0.7	-0.6	-0.2	-0.7
Vascular/heart problems diagnosed by doctor	0.6	1.6	5.6	0.5	2.4	1.1	-0.1	0.7	1.6	1.0	1.0	2.1	-0.7	2.3	-2.0	1.1	0.8	0.9	0.8	-0.9	-0.2	-0.1	-1.4	-0.9	-1.2	-1.6	-1.0
Cholesterol lowering medication	0.6	0.8	3.5	0.9	1.0	0.3	1.5	0.4	0.9	0.5	0.2	1.1	-1.2	1.3	1.4	0.8	1.9	0.2	0.4	-0.3	-0.9	-1.2	-0.4	-0.0	-0.3	-0.0	-0.9
Alzheimer’s Disease (in mother)	0.5	0.5	1.9	0.8	1.1	0.5	1.0	0.6	0.4	1.0	0.5	1.2	-0.1	1.4	-0.5	0.4	1.0	0.4	0.7	-0.6	-0.7	-0.8	-0.5	-0.5	-0.5	0.1	-0.7
Major Depression (MDD)	0.5	0.6	1.9	0.0	-0.2	0.3	1.4	1.0	0.6	0.5	0.4	0.3	-0.2	-0.5	1.2	0.9	0.3	1.1	1.0	-0.9	-1.4	-1.2	-0.5	-0.8	-0.8	-0.3	-0.9
Bipolar Disorder (2011)	0.5	0.5	5.7	-0.8	0.8	-0.4	-0.3	-0.2	-0.0	-1.1	-0.4	0.4	2.4	0.5	0.0	-0.7	1.1	-0.1	-0.1	0.0	0.6	0.3	-0.1	0.1	-0.1	0.7	0.1
Fasting Glucose	0.5	0.6	2.2	-0.4	-0.3	-0.7	-0.3	-0.7	-0.7	-0.6	-0.8	-0.2	1.5	0.0	-1.1	-0.6	0.0	-1.1	-1.0	0.8	0.9	0.7	0.8	0.9	0.8	0.7	0.7
HbA1C	0.5	0.5	1.2	1.1	0.4	0.9	0.8	0.8	0.7	0.1	0.8	0.1	0.5	0.2	-0.4	0.7	0.3	0.6	0.4	-0.8	-1.1	-1.0	-0.7	-0.8	-0.8	-0.7	-1.1
Hypothyroidism (self reported)	0.5	1.0	7.1	-0.5	-1.9	0.1	-0.1	-0.2	-0.8	-0.6	-0.2	-0.4	-0.8	-2.6	1.1	-0.7	-2.7	-0.0	0.1	0.1	0.6	1.1	0.7	-0.0	0.3	0.7	1.0
High blood pressure	0.5	1.4	5.0	-0.1	-2.2	-1.0	-0.1	-0.8	-1.5	-0.8	-1.0	-1.8	-0.0	-1.9	1.1	-1.2	-1.0	-1.1	-0.9	1.1	0.4	0.3	1.4	1.1	1.4	1.8	1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.7	-1.1	-0.9	-0.4	-0.7	-0.2	0.1	-0.0	-0.2	-0.0	1.7	-1.4	0.9	-0.9	-0.3	-0.3	-0.2	0.3	0.9	0.9	0.6	0.2	0.5	0.8	1.1
Neuroticism score	0.5	1.0	3.5	-1.9	-1.8	-1.3	-0.9	-0.6	-1.3	-0.7	-1.2	-1.8	-0.0	-1.8	0.6	-0.2	-0.9	-0.4	-1.0	0.6	-0.0	0.3	1.0	0.6	0.5	0.2	0.3
Lung cancer (father)	0.5	0.5	3.9	-0.3	-0.0	0.8	0.1	0.5	1.0	0.7	0.6	0.6	1.5	-0.3	0.4	-0.7	-2.0	0.5	0.6	-0.6	0.4	0.6	-0.4	-0.7	-0.3	0.8	0.3
Hair/balding pattern: Pattern 4	0.5	1.2	4.8	-0.7	1.9	1.1	1.3	1.1	0.3	0.9	0.9	0.6	-0.0	2.2	0.5	0.5	1.2	1.1	1.3	-1.1	-0.8	-1.5	-1.2	-1.2	-1.2	-0.5	-1.0
Body fat percentage	0.5	1.9	6.1	0.5	0.3	1.3	2.5	1.6	1.3	1.5	1.6	0.5	0.0	0.1	1.3	1.4	2.1	1.4	1.5	-1.3	-1.8	-1.7	-1.1	-1.4	-1.3	-1.1	-1.4
Medication: Blood pressure	0.5	0.9	4.1	0.2	-1.0	-0.7	-0.0	-0.8	-1.5	-0.7	-0.7	-1.4	0.4	-0.8	2.0	-1.2	-0.5	-0.9	-0.6	0.9	0.6	0.3	0.9	0.8	1.1	1.2	1.0
Supplements: Vitamin C	0.5	0.6	1.6	-0.6	-0.9	-0.7	-0.7	-0.6	-0.9	-0.1	-0.7	-0.4	0.5	-0.7	-0.7	-1.0	-0.7	-0.8	-0.5	0.6	0.8	0.6	0.9	0.6	0.8	1.3	1.1
Bipolar Disorder or Schizophrenia	0.4	0.9	8.3	-2.2	-0.7	0.1	0.5	-0.1	-0.3	-0.6	0.2	-0.2	2.9	-1.1	-1.6	-0.9	-0.2	-0.0	0.0	-0.2	0.5	0.5	0.2	-0.3	0.1	1.0	0.8
Breast Cancer	0.4	1.0	7.2	2.7	1.0	0.3	1.3	0.4	0.6	0.1	0.2	1.1	0.1	2.0	0.9	0.4	2.7	-0.0	0.3	-0.1	-0.1	-0.7	-0.3	-0.1	-0.2	0.0	-0.3
Age at First Birth	0.4	0.6	1.3	-1.1	-0.4	-0.8	-0.1	-0.6	-1.0	-0.7	-1.0	-0.8	1.0	-0.1	-0.3	-0.7	-1.1	-0.6	-0.7	0.6	1.0	0.9	0.8	0.6	0.7	0.8	1.0
Rheumatoid Arthritis	0.4	0.5	5.4	-0.1	0.3	0.6	-0.5	-0.3	0.8	0.6	0.7	0.4	0.4	-0.3	2.3	-0.2	-1.9	-0.0	-0.3	-0.2	0.2	0.3	-0.4	-0.2	-0.0	-0.3	-0.0
Taking other prescription medications	0.4	0.6	3.3	-0.5	-1.4	-0.4	-0.2	-0.3	-0.3	-0.3	-0.7	-0.3	-0.7	-1.8	1.4	-0.5	-1.6	-0.2	-0.3	0.3	-0.0	0.3	0.8	0.4	0.3	0.9	0.3
Age when periods started (menarche)	0.4	1.1	5.2	0.3	1.7	0.3	-0.3	0.2	0.9	0.2	-0.1	0.9	-1.3	1.8	-0.5	1.9	-1.3	0.5	-0.2	-0.3	-0.8	-0.6	-0.9	-0.1	-0.9	-2.3	-1.6
Medication: Levothyroxine sodium	0.4	0.7	3.3	-0.9	-1.6	-0.4	-0.4	-0.5	-0.7	-0.5	-0.6	-0.5	-0.1	-1.8	0.3	-0.9	-1.7	-0.4	-0.4	0.4	0.9	1.1	0.8	0.2	0.4	0.9	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.7	-1.2	-1.3	-0.8	-0.5	-0.2	-1.6	0.1	-0.4	-1.6	-1.1	-1.6	-0.4	-0.1	-0.3	-0.0	-0.2	0.3	-0.4	-0.2	0.6	0.1	0.2	-0.1	0.1
Pulse wave Arterial Stiffness index	0.4	0.5	2.4	-1.2	-0.3	-0.5	-0.0	-0.3	-0.0	-0.8	-0.6	-0.1	1.5	-0.5	1.4	-0.9	-0.0	-0.3	-0.4	0.3	0.7	0.8	0.4	0.3	0.3	0.9	0.6
Birth weight of first child	0.4	0.8	2.9	1.1	1.2	1.1	1.0	0.7	1.2	1.7	1.1	1.1	0.6	1.4	-1.1	-0.0	1.0	0.4	0.6	-0.7	0.3	0.1	-0.9	-0.8	-0.4	0.1	0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.0	-1.2	-0.8	-1.0	-1.1	-0.8	-0.3	-0.9	-1.0	0.0	0.2	-1.0	-1.7	-0.3	-0.5	-0.6	-0.8	0.7	0.6	0.9	0.9	0.8	0.6	0.6	0.5
Gout (self-reported)	0.4	0.5	1.5	0.4	0.7	0.7	0.9	0.6	0.9	0.8	0.6	0.8	-0.8	0.8	-1.2	0.8	0.4	0.5	0.4	-0.5	-0.6	-0.5	-0.6	-0.5	-0.6	-0.9	-0.7
Comparative body size at age 10	0.4	1.1	2.7	0.6	0.3	1.3	1.7	1.1	0.7	1.4	1.4	0.2	-0.4	-0.0	-0.7	1.3	1.2	1.1	1.3	-1.0	-1.2	-1.2	-1.0	-1.1	-0.9	-1.4	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.2	-0.9	-0.8	-0.9	-0.9	-0.5	-1.1	-1.0	-0.8	-1.1	-0.8	-0.8	-0.6	-0.8	0.3	-0.3	-0.7	0.2	0.3	0.1	0.6	0.2	0.2	1.0	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	3.2	-0.5	-0.6	0.6	0.7	-0.0	0.8	0.7	0.5	0.7	1.8	-0.6	-0.3	-0.3	-1.6	-0.2	0.0	-0.1	0.1	0.1	0.0	-0.1	0.3	0.9	0.3
Medication: Allopurinol	0.4	0.6	1.3	0.4	0.8	0.9	1.1	0.6	0.7	1.1	0.9	0.6	-0.9	0.9	-0.8	0.8	0.7	0.6	0.5	-0.6	-0.8	-0.7	-0.8	-0.5	-0.5	-0.9	-0.9
Heart disease (mother)	0.4	0.5	2.0	-0.1	0.6	0.4	1.1	0.7	-0.1	0.8	0.5	-0.3	-0.4	0.7	0.3	0.3	1.4	0.7	0.8	-0.7	-0.7	-1.0	-0.6	-0.8	-0.7	-0.3	-0.5
Alcohol intake frequency.	0.4	0.9	2.7	-0.3	-1.6	-1.3	-0.6	-0.8	-1.4	-0.3	-1.3	-0.4	-0.4	-1.6	1.1	-0.3	-0.9	-0.8	-0.5	0.9	-0.1	0.4	1.5	1.1	0.8	0.9	0.3
Hypertension (Self-reported)	0.4	1.2	4.0	0.2	-2.0	-0.9	-0.1	-0.8	-1.5	-0.6	-0.8	-1.5	0.3	-1.7	1.0	-1.3	-0.7	-1.0	-0.6	0.9	0.5	0.4	1.3	1.0	1.3	1.8	1.2
Ever had bowel cancer screening	0.4	0.5	1.9	-1.3	-0.8	-1.0	-1.1	-0.5	-1.4	-0.4	-1.0	-0.2	0.1	-0.8	-0.3	-0.5	-0.1	-0.4	-0.2	0.5	0.1	0.5	0.9	0.6	0.3	0.7	0.1
Qualifications: nursing, teaching	0.4	0.6	1.6	-0.9	-1.0	-0.8	-0.8	-0.5	-1.0	-1.3	-0.7	-1.1	0.9	-0.6	-0.8	-1.0	-0.4	-0.5	-0.6	0.4	0.5	0.5	0.6	0.4	0.5	1.2	0.6
Mineral and other dietary supplements	0.4	0.5	2.7	-0.3	-0.3	-0.4	-0.4	-0.6	-0.7	-0.9	-0.5	-0.8	1.2	-0.6	1.6	-0.7	-0.4	-0.2	-0.4	0.4	1.0	0.7	0.4	0.1	0.3	0.0	1.1
Breast cancer (self-reported)	0.4	0.5	2.4	-1.6	-0.9	-0.7	-1.0	-0.2	-0.3	-0.8	-0.4	-1.2	0.0	-1.1	-1.0	-0.1	-1.1	-0.1	-0.6	0.1	-0.0	0.2	0.3	0.1	0.0	-0.1	0.1
Wears glasses or contact lenses	0.4	0.4	2.6	-1.6	-0.1	-0.8	-0.9	-0.7	-0.3	-0.7	-0.9	-0.2	-0.8	-0.2	0.2	0.2	-0.8	-0.5	-0.8	0.7	0.5	0.5	0.5	0.8	0.4	-0.4	0.2
Hearing aid user	0.4	0.5	3.2	0.6	1.3	0.7	0.3	0.2	0.9	0.9	0.6	0.9	-0.0	1.3	1.8	0.3	-0.0	-0.2	-0.0	0.1	0.2	0.2	-0.5	0.1	0.1	-0.5	-0.4
Risk taking	0.4	0.6	2.6	-1.6	-1.1	-0.7	-1.1	-0.2	-1.0	-1.2	-0.8	-1.2	0.6	-0.9	-1.0	-0.4	0.0	-0.0	-0.4	0.1	0.5	0.3	0.5	-0.0	-0.0	0.4	0.7
Basal cell carcinoma (self-reported)	0.4	0.5	2.9	-0.2	0.7	0.1	0.6	0.8	0.0	1.3	0.2	0.3	1.2	1.1	-1.7	0.1	1.1	0.5	0.8	-0.6	-0.4	-0.6	-0.3	-0.6	-0.5	0.2	-0.4
Neuroticism (Nagel 2018)	0.3	0.7	2.7	-1.6	-0.9	-1.2	-0.8	-0.8	-0.9	-0.4	-1.0	-0.9	-0.5	-1.1	0.7	0.0	-0.7	-0.7	-1.0	0.8	0.2	0.5	0.8	1.0	0.7	-0.1	0.2
Schizophrenia (2018)	0.3	0.6	5.2	-1.3	0.3	0.7	1.3	0.5	0.6	0.2	0.6	0.9	2.3	0.1	0.0	-0.1	0.2	0.8	0.7	-0.9	-0.3	-0.2	-0.5	-1.0	-0.8	0.2	-0.1
Heel T-Score	0.3	2.6	10.0	-3.2	0.7	0.4	2.9	1.2	-0.5	0.2	0.3	-1.1	1.3	1.2	-0.8	1.9	2.2	1.2	0.9	-1.0	-2.5	-2.8	-1.0	-0.8	-1.3	-1.2	-2.3
Smoking Status	0.3	0.6	4.7	1.6	-0.3	0.5	0.1	0.6	1.0	0.9	0.6	1.0	-2.2	-0.5	-0.2	0.8	-0.8	0.6	0.8	-0.3	-0.5	-0.0	-0.2	-0.3	-0.2	-0.9	-0.3
Number of treatments/medications taken	0.3	0.5	2.4	-0.9	-1.1	0.0	0.7	0.0	-0.2	0.5	-0.1	-0.2	-1.2	-1.6	1.5	-0.6	-1.2	-0.1	-0.0	-0.0	-0.5	-0.2	0.5	0.1	0.2	1.3	0.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.9	-0.1	-0.4	0.3	0.6	0.7	0.2	0.6	0.3	0.8	-0.8	-0.2	-0.8	0.8	0.4	0.7	0.8	-0.6	-1.0	-0.5	-0.3	-0.5	-0.6	-0.4	-0.8
Ever had hysterectomy (womb removed)	0.3	0.3	1.2	1.0	-0.3	-0.0	-0.1	-0.4	0.3	0.2	0.1	0.6	-1.0	0.0	0.7	-0.5	0.1	-0.7	-0.3	0.6	0.1	0.2	0.5	0.8	0.9	1.1	0.2
Angina	0.3	0.3	2.9	-1.0	-0.9	-0.8	-0.2	-0.0	-0.4	-0.7	-0.7	-0.2	0.6	-0.7	1.7	-0.2	0.4	-0.1	-0.2	0.1	-0.2	-0.0	0.5	0.2	-0.1	0.5	0.0
Medication: Co-codamol	0.3	0.3	1.6	0.1	-1.3	-0.3	-0.2	-0.1	-0.6	0.6	-0.1	-0.6	-0.6	-1.3	0.8	0.1	-0.1	-0.4	-0.3	0.5	-0.4	-0.2	0.7	0.5	0.6	0.1	0.0
Average weekly fortified wine intake	0.3	0.4	3.0	0.4	0.3	0.2	-0.2	-0.4	0.5	-0.0	0.1	0.2	-0.5	0.5	-1.7	-0.5	0.4	-0.8	-0.6	0.6	0.9	0.8	0.2	0.6	0.7	0.5	0.6
Fed-up feelings	0.3	0.6	7.6	-1.0	-0.9	-0.7	0.4	-0.1	-0.6	-0.7	-0.6	-0.8	0.3	-1.3	2.8	0.4	0.6	0.2	-0.2	-0.1	-0.6	-0.3	0.3	-0.0	-0.2	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	4.5	-1.7	0.5	0.2	1.1	0.3	-0.4	-0.5	0.3	-0.9	2.1	0.5	-0.7	0.0	1.6	0.2	0.1	-0.3	-0.6	-1.1	-0.5	-0.3	-0.4	0.0	-0.6
Nervous feelings	0.3	0.6	2.7	-1.7	-0.9	-0.7	-0.6	-0.6	-0.7	0.4	-0.7	-0.5	-1.1	-0.9	-1.2	0.7	-1.2	-0.3	-0.5	0.6	-0.4	0.1	0.6	0.7	0.3	-0.9	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	5.8	-2.0	-0.1	-0.0	0.4	0.1	-0.4	-0.8	0.1	-1.0	2.4	0.0	-2.1	-0.5	1.1	-0.0	-0.2	-0.1	-0.0	-0.5	-0.2	-0.1	-0.1	0.6	-0.0
Financial difficulties in last 2 years	0.3	0.4	2.5	-0.7	-1.2	-0.8	-0.4	0.0	-1.0	-0.6	-0.6	-0.7	-0.7	-1.2	1.6	-0.2	0.2	0.1	0.1	-0.1	-0.1	0.0	0.5	-0.2	-0.2	0.2	0.3
Heart attack	0.3	0.4	4.7	-0.7	-0.8	-0.3	0.7	0.1	0.1	0.3	-0.1	-0.1	0.7	-0.6	2.2	-0.2	-0.5	-0.1	0.1	-0.0	-0.4	-0.1	0.3	0.2	0.2	0.8	-0.1
Pain all over the body in last month	0.3	0.3	0.9	-0.5	-0.0	0.1	0.2	0.7	0.4	0.4	0.2	0.4	0.3	0.1	0.8	0.1	0.5	0.8	0.6	-1.0	-0.5	-0.3	-0.4	-0.9	-0.9	0.2	-0.4
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.2	-1.0	-0.2	-0.3	-0.2	-0.3	0.3	-1.0	-0.6	-0.1	1.5	-0.5	-0.0	-0.7	-1.2	-0.1	-0.5	0.0	0.2	0.3	0.3	0.2	0.0	1.0	0.1
Exposure to tobacco smoke at home	0.3	0.4	1.4	0.0	-0.4	-0.1	0.2	0.4	-0.3	0.4	-0.2	-0.0	-1.2	-0.6	1.1	0.7	-0.7	0.6	0.5	-0.4	-1.2	-0.8	-0.0	-0.2	-0.7	-0.5	-1.0
Medication: Paracetamol	0.3	0.4	3.5	-0.2	-0.6	-0.7	0.1	-0.4	-0.5	-0.6	-0.5	-0.8	-0.8	-0.8	1.9	-0.1	0.2	-0.6	-0.7	0.6	-0.0	0.4	0.7	0.8	0.7	0.3	0.1
Glaucoma (self-reported)	0.3	0.3	3.7	0.7	0.4	0.1	-0.5	0.0	-0.3	-0.1	0.1	-0.1	-0.5	0.5	-1.9	0.5	1.0	-0.1	0.1	0.2	0.2	0.2	-0.2	0.0	0.0	-1.1	-0.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	3.5	-0.5	-0.4	-0.1	-0.1	-0.3	0.4	-0.3	-0.1	0.6	1.9	-0.4	-0.5	-0.7	0.1	-0.5	-0.1	0.4	0.9	0.9	0.4	0.3	0.5	0.9	1.0
Medication: Ibuprofen	0.3	0.4	0.9	-0.1	0.1	-0.9	-0.6	-0.5	-0.8	-0.5	-0.9	-0.3	0.6	0.3	-1.0	-0.7	0.8	-0.7	-0.6	0.6	0.5	0.5	0.6	0.8	0.5	0.9	0.4
Leg pain on walking	0.3	0.4	3.1	0.2	-0.5	0.1	0.2	0.4	0.1	0.5	0.1	-0.1	-1.2	-0.3	1.8	1.1	0.1	0.2	0.0	-0.2	-0.2	-0.0	-0.1	-0.3	-0.4	-1.4	-0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.1	0.4	0.7	1.1	1.1	0.2	1.1	0.6	0.9	0.7	0.8	0.9	0.3	0.3	0.6	0.2	0.1	-0.3	-0.4	-0.4	-0.6	-0.2	-0.1	-0.0	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	3.2	0.7	0.2	0.4	0.2	0.2	0.6	0.6	0.3	0.8	-0.8	0.4	1.8	0.6	-0.4	0.1	0.2	-0.2	-0.6	-0.5	-0.2	-0.1	-0.2	-0.1	-0.6
Long-standing illness, disability or infirmity	0.3	0.4	1.8	-1.4	-0.9	-0.5	-0.0	-0.2	-0.8	-0.3	-0.7	-0.1	0.1	-1.0	1.2	-0.4	-1.3	0.2	0.1	-0.2	0.0	0.0	0.5	-0.2	-0.2	0.7	0.3
Illnesses of father: None of the above (group 1)	0.3	0.3	2.4	0.4	-0.3	-0.2	-0.5	-0.6	0.0	0.1	-0.4	0.5	0.2	-0.1	-0.0	0.1	-1.6	-0.5	-0.5	0.7	0.7	0.9	0.5	0.7	0.6	-0.2	0.6
Number of self-reported non-cancer illnesses	0.3	0.6	3.5	-0.4	-1.8	0.1	0.3	0.1	-0.3	0.4	0.0	-0.4	0.6	-1.9	1.3	-0.6	-1.4	0.1	0.1	-0.2	-0.2	0.3	0.5	-0.1	0.2	1.2	0.4
Mother’s age at death	0.3	0.3	1.7	0.6	1.0	0.6	0.6	0.1	0.4	0.6	0.6	0.7	1.3	1.2	-0.5	0.1	1.0	-0.0	0.0	-0.2	0.1	-0.0	-0.5	-0.1	-0.1	0.1	-0.2
Financial situation satisfaction	0.3	0.4	2.0	-0.5	-0.9	-0.4	-0.4	0.0	-0.6	-0.2	-0.5	-0.4	-1.1	-1.0	1.4	0.5	-1.1	0.4	0.0	-0.1	-0.3	0.2	0.3	-0.1	-0.3	-0.6	-0.1
Medication: Lisinopril	0.3	0.4	2.3	-0.7	-1.1	-0.6	-0.0	-0.2	-0.9	-0.8	-0.5	-1.5	0.4	-1.1	1.1	-0.4	-0.5	0.1	-0.2	0.1	-0.2	-0.4	0.4	0.0	0.2	0.5	0.2
Fractured/broken bones in last 5 years	0.3	0.3	2.7	1.0	0.8	0.4	0.2	0.3	0.4	0.2	0.4	-0.1	-1.6	1.0	-0.3	0.1	1.0	0.2	0.2	-0.2	-0.1	-0.3	-0.6	-0.3	-0.2	-0.2	-0.3
Age started oral contraceptive pill	0.3	0.4	2.0	-1.4	0.1	-0.8	-0.7	-0.6	0.0	-0.1	-1.0	1.1	-0.7	0.3	-1.2	0.5	-0.8	-0.3	-0.4	0.3	0.2	0.7	0.4	0.6	0.0	-0.3	-0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	4.1	-0.7	-0.8	-0.2	0.5	-0.0	0.1	0.3	-0.1	-0.2	0.7	-0.7	2.0	-0.4	-0.8	-0.2	-0.0	0.0	-0.3	0.1	0.4	0.2	0.3	0.9	0.0
Heart disease (siblings)	0.3	0.3	2.2	-0.8	-0.5	0.4	0.4	0.5	0.3	1.1	0.6	-0.3	-0.7	-0.3	-1.5	0.3	-0.3	0.4	0.4	-0.5	-0.5	-0.3	-0.3	-0.5	-0.3	-0.4	-0.2
Body Mass Index (BMI) (2010)	0.2	0.2	2.1	-0.4	0.4	0.0	0.2	0.1	-0.3	-0.2	0.2	-0.9	-0.9	0.5	0.1	-0.6	1.4	-0.0	0.1	0.1	0.2	-0.2	-0.2	-0.0	0.1	0.2	0.2
Mean Putamen Volume	0.2	0.3	1.6	-0.7	0.1	0.0	-0.1	-0.6	-0.2	-0.2	0.0	0.2	1.3	0.1	0.3	-0.9	-0.2	-0.5	-0.4	0.4	0.7	0.4	0.1	0.4	0.6	0.9	0.6
Schizophrenia (2014)	0.2	0.4	5.3	-1.2	-0.3	0.0	0.5	0.0	0.0	-0.4	-0.1	0.3	2.3	-0.4	0.0	-0.4	-0.0	0.3	0.2	-0.4	0.2	0.3	0.0	-0.4	-0.3	0.5	0.4
Blood Red Count	0.2	1.9	6.7	0.9	2.1	1.2	2.0	1.0	1.2	2.0	1.4	1.5	0.8	2.6	1.6	0.6	2.5	0.5	1.2	-0.6	-0.9	-1.2	-1.2	-0.5	-0.7	-0.3	-1.3
BMI	0.2	1.4	6.1	-2.2	-1.9	-0.9	0.0	-0.4	-1.1	-1.7	-0.5	-2.4	1.5	-2.5	0.0	-1.0	-0.0	-0.4	-0.5	0.5	0.1	-0.0	0.9	0.4	0.6	1.1	0.7
Hearing difficulty/problems: Yes	0.2	0.2	1.3	0.3	0.2	-0.0	-0.0	0.2	0.5	0.6	-0.2	0.5	-0.7	0.4	0.6	0.9	-1.2	0.0	0.0	0.0	-0.6	-0.1	0.0	0.2	-0.2	-0.6	-0.7
Medication for hormone replacement therapy	0.2	0.3	1.2	0.5	0.4	0.3	-0.2	0.5	0.5	0.5	0.5	1.1	-0.5	0.4	-0.4	0.6	0.7	0.4	0.5	-0.4	-0.6	-0.1	-0.5	-0.3	-0.4	-0.5	-0.8
Severe depression (siblings)	0.2	0.3	2.1	-0.9	-0.8	0.1	0.2	0.1	-0.1	0.2	-0.1	-0.6	0.3	-0.9	-1.0	0.0	-1.5	0.2	0.2	-0.2	-0.3	0.1	0.2	-0.1	0.0	0.3	0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	0.8	-0.6	0.2	0.1	0.5	0.9	-0.3	0.1	0.3	0.1	-0.2	0.1	0.5	-0.4	0.6	0.2	-0.6	-0.7	-0.3	-0.2	-0.4	-0.4	0.3	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.3	1.3	-0.8	0.3	-0.7	-0.4	-0.5	-0.5	-0.6	-0.9	-0.0	1.1	0.6	0.2	-0.7	0.3	-0.5	-0.6	0.5	0.6	0.3	0.4	0.6	0.3	0.8	0.3
Supplements: Glucosamine	0.2	0.3	4.5	-0.8	-0.1	-0.3	0.5	0.1	-0.2	0.4	-0.3	0.3	0.2	0.2	-2.1	0.4	0.3	-0.2	-0.0	0.2	-0.1	0.2	0.3	0.3	0.2	-0.0	-0.0
Body mass index (BMI)	0.2	0.8	4.3	-1.4	-1.7	-0.5	0.7	-0.1	-0.6	-0.9	-0.1	-1.7	1.2	-2.1	1.0	-0.5	0.3	-0.2	-0.2	0.2	-0.2	-0.1	0.6	0.2	0.4	0.7	0.3
Had other major operations	0.2	0.2	2.1	-0.5	-0.2	0.2	0.4	0.2	0.6	0.5	0.5	0.3	0.3	-0.1	1.4	0.2	0.1	0.2	0.0	-0.4	-0.6	-0.4	-0.2	-0.3	-0.3	0.0	-0.5
Falls in the last year	0.2	0.2	1.1	0.0	-0.0	0.1	0.5	0.6	-0.3	-0.1	-0.0	-0.4	-1.0	0.0	0.2	0.6	0.0	0.6	0.3	-0.7	-0.7	-0.6	-0.3	-0.7	-0.8	-0.5	-0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	2.3	0.3	0.4	0.4	-0.0	0.3	0.7	0.3	0.3	1.4	1.5	0.3	0.8	-0.4	0.2	0.4	0.4	-0.5	0.3	0.4	-0.3	-0.5	-0.5	0.4	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	2.0	0.3	0.6	-0.8	-0.3	-0.2	-0.6	-0.3	-0.8	0.1	0.3	0.8	-0.8	-0.1	1.4	-0.3	-0.2	0.3	0.3	0.1	0.3	0.4	0.1	0.3	0.1
Depression (self-reported)	0.2	0.2	1.2	1.1	0.2	-0.0	-0.2	0.2	0.7	0.2	0.4	0.5	0.3	-0.0	-0.6	-0.0	1.0	0.1	0.2	-0.2	-0.5	-0.3	-0.2	-0.1	-0.0	0.3	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	2.8	0.0	-0.3	0.2	0.2	0.2	0.2	0.8	0.2	-0.4	-0.7	-0.1	1.7	0.4	-0.6	0.3	0.2	-0.2	-0.0	-0.0	-0.2	-0.3	-0.3	-0.9	0.1
Medication: Amlodipine	0.2	0.3	3.7	0.9	-0.3	0.2	-0.1	-0.2	0.5	0.1	0.2	0.0	-1.9	-0.0	-0.2	-0.5	-0.1	-0.3	-0.3	0.1	0.0	-0.1	0.1	0.2	0.3	1.0	0.1
Number of children fathered	0.2	0.3	1.1	0.2	0.6	0.0	0.1	-0.5	0.0	0.2	0.1	-0.1	0.6	1.1	-0.4	-0.5	1.0	-0.8	-0.5	0.6	0.8	0.3	0.1	0.5	0.6	0.3	0.5
Medication for pain relief, constipation, heartburn	0.2	0.4	2.8	-0.5	-0.2	0.1	-0.6	-0.7	0.0	-0.2	-0.1	0.0	0.6	-0.2	-1.2	-0.7	-1.7	-0.5	-0.3	0.5	0.9	0.7	0.2	0.4	0.6	0.5	0.8
Neck or shoulder pain in last month	0.2	0.3	2.4	-1.0	-0.1	-0.3	0.5	0.4	-0.7	-0.1	-0.4	0.5	1.6	-0.1	-0.2	-0.3	0.1	0.5	0.7	-0.6	-0.1	0.0	0.1	-0.6	-0.7	0.6	0.0
Had major operations	0.2	0.3	2.5	1.1	-0.1	0.2	0.5	0.4	-0.1	0.9	0.2	0.3	-0.1	0.1	1.6	0.6	0.1	0.2	0.4	-0.2	-0.4	-0.4	-0.1	-0.3	-0.2	-0.5	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.8	0.3	0.0	0.0	0.1	-0.2	0.4	0.7	-0.2	0.4	-0.3	0.5	1.3	-0.1	-0.9	-0.3	-0.3	0.2	-0.1	0.1	0.1	0.5	0.3	0.5	-0.2
Loneliness, isolation	0.2	0.3	1.2	0.3	-0.2	0.2	0.5	0.6	-0.0	0.4	0.4	-0.1	0.1	-0.5	1.0	0.3	1.1	0.6	0.6	-0.5	-0.8	-0.4	-0.3	-0.5	-0.5	-0.1	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.2	0.2	-0.1	-0.0	-0.0	0.4	-0.5	-0.5	0.3	-0.6	-0.1	0.1	0.4	0.2	1.1	0.5	0.4	-0.2	-0.6	-0.5	-0.4	-0.2	-0.4	-0.5	-0.6
Smoking status: Current	0.2	0.2	1.9	0.7	-0.4	0.3	0.0	0.2	0.8	0.7	0.5	0.6	-1.4	-0.8	0.1	0.2	-0.6	0.2	0.3	-0.1	-0.2	0.3	-0.0	-0.1	-0.0	-0.1	-0.1
Miserableness	0.2	0.3	0.6	-0.3	0.1	0.2	0.4	0.6	0.4	0.3	0.5	0.1	-0.8	-0.3	0.1	0.5	0.7	0.7	0.5	-0.7	-0.7	-0.7	-0.6	-0.8	-0.7	-0.6	-0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.5	-0.4	0.4	0.3	1.1	0.6	0.2	0.3	0.5	0.2	0.1	-0.1	-0.8	-0.4	1.2	0.2	0.6	-0.4	-0.2	-0.6	-0.2	-0.5	-0.2	0.6	0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	3.2	0.1	-0.1	0.0	0.2	0.2	-0.3	0.2	0.0	0.1	-1.8	0.3	-1.4	0.2	-0.1	-0.2	-0.0	0.0	-0.6	-0.5	0.1	0.2	0.1	0.2	-0.5
Medication: Paracetamol	0.2	0.3	0.8	-0.3	-0.3	-0.7	-0.2	-0.4	-0.7	-0.8	-0.6	-0.6	-0.7	-0.5	0.7	-0.7	0.4	-0.6	-0.6	0.6	0.2	0.5	0.6	0.8	0.7	0.9	0.2
Ever smoked	0.2	0.4	2.2	0.8	-0.8	-0.3	-0.9	-0.1	-0.1	0.3	-0.2	0.2	-1.5	-0.9	-0.7	0.2	-1.4	0.1	0.3	0.3	-0.1	0.4	0.4	0.3	0.2	-0.3	0.0
Diastolic blood pressure, automated reading	0.2	0.5	2.5	-0.7	-1.1	-0.4	-0.2	-0.5	-0.5	0.1	0.0	-0.9	-0.0	-1.6	-0.8	-0.9	0.1	-0.8	-0.4	0.6	0.2	0.1	0.7	0.6	0.9	1.2	0.6
Depressed Affect (Nagel 2018)	0.1	0.2	1.2	-1.0	-0.5	-0.6	-0.0	-0.1	-0.4	-0.4	-0.5	-0.5	-0.4	-0.8	1.1	0.4	0.5	0.2	-0.3	0.1	-0.3	-0.2	0.2	0.1	-0.1	-0.4	-0.1
Crohns Disease (2017)	0.1	0.2	0.9	0.1	-0.2	-0.3	-0.7	-0.1	-0.5	-1.0	-0.4	-0.7	-0.5	-0.2	-0.2	-0.6	-0.4	-0.0	-0.1	0.0	0.3	0.4	0.2	0.1	0.0	0.5	0.2
Primary Biliary Cirrhosis	0.1	0.1	1.0	-0.1	0.3	0.1	-0.1	-0.2	0.1	0.4	0.1	0.5	0.3	0.2	-1.0	-0.6	0.1	-0.0	0.1	-0.3	-0.0	-0.1	-0.1	-0.2	-0.1	0.7	-0.0
Blood Eosinophil Count	0.1	0.8	4.9	-2.2	-0.7	-0.1	-0.2	-0.2	-0.9	-1.2	-0.0	-1.9	-0.6	-1.3	1.3	-0.7	-0.1	0.5	-0.1	-0.3	-0.8	-1.0	-0.1	-0.3	-0.5	0.5	-0.7
Allergy or Eczema	0.1	0.3	1.4	-1.2	-0.1	-0.7	-0.3	-0.3	-0.7	-0.7	-0.9	-0.8	1.1	0.2	0.3	-0.3	-0.3	-0.3	-0.7	0.3	0.2	-0.2	0.3	0.4	0.0	0.5	-0.0
Cardiovascular Disease	0.1	0.2	0.8	0.1	-0.5	-0.3	0.2	-0.1	-0.9	0.2	0.1	-0.7	-0.2	-0.4	-0.6	-0.5	0.9	-0.2	0.2	0.2	-0.4	-0.8	0.3	0.2	0.5	0.8	0.1
Trunk fat percentage	0.1	0.5	1.9	-1.2	-0.7	0.0	1.0	0.0	0.1	0.3	0.3	-0.7	1.4	-0.9	1.3	-0.8	1.2	-0.2	-0.0	0.0	0.3	0.3	0.3	-0.1	0.3	0.9	0.6
Current tobacco smoking	0.1	0.2	1.2	0.6	-0.4	0.3	-0.1	0.2	0.8	0.6	0.5	0.6	-1.1	-0.8	0.1	0.1	-0.3	0.2	0.3	-0.2	-0.1	0.4	-0.1	-0.1	-0.0	-0.0	-0.0
Hearing difficulty/problems with background noise	0.1	0.2	1.4	-0.6	-0.0	-0.6	-0.6	-0.4	-0.2	0.3	-0.8	0.1	-0.5	0.1	-0.3	0.2	-1.2	-0.4	-0.4	0.4	0.3	0.6	0.4	0.5	0.3	-0.1	0.2
Breastfed as a baby	0.1	0.2	0.9	0.2	-0.2	-0.3	-0.5	-0.5	0.0	0.2	-0.3	0.5	-0.4	-0.1	0.7	0.1	-1.0	-0.4	-0.5	0.3	-0.3	-0.0	0.2	0.6	0.3	0.3	-0.4
Worry too long after embarrassment	0.1	0.3	1.3	-0.9	-0.4	-0.6	-0.6	-0.4	-0.6	0.0	-0.5	-1.1	0.3	-0.0	-0.6	-0.2	0.2	-0.4	-0.7	0.5	0.2	0.2	0.3	0.5	0.5	-0.1	0.1
Eye problems/disorders: None of the above	0.1	0.1	0.6	-0.3	0.2	0.1	-0.5	-0.2	0.8	-0.2	0.1	0.2	0.5	0.2	0.2	-0.4	0.1	-0.3	-0.4	0.1	0.6	0.6	-0.1	0.1	0.1	0.3	0.3
Medication: Omeprazole	0.1	0.2	2.1	0.6	0.2	0.1	0.3	-0.2	-0.1	0.4	0.1	0.0	0.1	0.3	1.4	0.0	0.1	-0.4	-0.2	0.5	0.0	-0.3	0.1	0.5	0.5	0.1	0.0
Friendships satisfaction	0.1	0.2	0.9	-0.2	-0.7	0.0	0.4	0.2	-0.2	-0.6	0.3	-0.6	1.0	-0.7	0.1	-0.4	0.8	-0.1	-0.2	-0.1	-0.1	0.0	0.1	-0.1	0.2	0.7	0.1
Medication for cholesterol	0.1	0.2	0.7	0.6	0.5	0.6	-0.2	0.4	-0.2	0.4	0.4	0.1	0.8	0.5	-0.4	-0.3	-0.6	0.5	0.6	-0.5	0.4	0.4	-0.4	-0.7	-0.5	-0.3	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.9	-0.1	-0.6	-0.3	-0.4	-0.2	-0.2	-0.6	-0.5	-0.4	0.4	-0.5	0.3	-0.4	0.5	-0.0	-0.4	0.2	0.6	1.0	0.4	0.1	0.1	0.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	1.1	0.6	0.3	0.2	0.3	0.0	0.1	0.4	0.2	-0.0	-0.3	0.4	1.0	-0.2	0.5	-0.3	-0.2	0.3	-0.1	-0.4	0.1	0.4	0.4	0.4	-0.0
Supplements: Calcium	0.1	0.2	0.6	-0.2	-0.1	0.3	0.1	0.5	0.1	0.2	0.3	-0.2	0.3	-0.3	0.8	-0.0	-0.3	0.6	0.4	-0.7	-0.5	-0.3	-0.3	-0.6	-0.6	0.3	-0.4
Blood White Count	0.0	0.3	1.2	-1.0	-0.3	0.3	0.4	0.0	0.4	1.1	0.7	1.1	0.8	-0.3	-0.2	-0.8	0.5	-0.0	0.6	-0.1	0.2	0.2	0.1	-0.1	0.1	0.9	0.4

Hub : Genes

CEP250

Models

Trait associations