[Hub]/) : Traits : Schizophrenia (2014) : ←

chr22:39,192,995-43,232,818

Best TWAS P=2.13e-10 · Best GWAS P=1.55e-10 conditioned to 0.00236

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM109B	0.06	0.02	blup	337	0.03	7.4e-05	-4.5	5.5	3.7e-08	0.01	0.32	0.67	FALSE
2	CommonMind	Brain Pre-frontal Cortex	NAGA	0.09	0.09	blup	336	0.13	1.2e-15	-4.5	5.8	8.6e-09	0.04	0.54	0.46	FALSE
3	GTEx	Adrenal Gland	SMDT1	0.28	0.22	lasso	2	0.20	1.3e-07	-5.2	5.2	1.5e-07	0.00	0.27	0.69	FALSE
4	GTEx	Artery Aorta	L3MBTL2	0.14	0.01	lasso	6	0.04	1.8e-03	-4.0	5.1	2.7e-07	-0.11	0.02	0.86	FALSE
5	GTEx	Brain Cortex	FAM109B	0.13	0.10	enet	14	0.09	2.2e-03	-5.1	5.3	9.5e-08	0.00	0.16	0.43	FALSE
6	GTEx	Brain Hypothalamus	CENPM	0.54	0.28	lasso	3	0.26	8.5e-07	-5.1	-5.7	9.0e-09	-0.07	0.05	0.80	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	CENPM	0.35	0.12	lasso	8	0.23	6.8e-07	-4.6	-5.3	9.1e-08	-0.07	0.01	0.97	FALSE
8	GTEx	Breast Mammary Tissue (Male)	SMDT1	0.40	0.38	lasso	1	0.38	1.2e-09	-5.2	5.2	2.3e-07	0.00	0.28	0.71	FALSE
9	GTEx	Breast Mammary Tissue (Female)	SMDT1	0.50	0.38	lasso	5	0.36	1.1e-11	-5.0	5.1	3.0e-07	0.02	0.32	0.68	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	SMDT1	0.40	0.57	lasso	7	0.58	3.4e-25	-5.2	5.2	2.4e-07	0.00	0.29	0.71	FALSE
11	GTEx	Esophagus Muscularis	MGAT3	0.09	0.02	enet	15	0.02	1.3e-02	6.1	-6.4	2.1e-10	-0.70	0.04	0.80	TRUE
12	GTEx	Esophagus Muscularis	FAM109B	0.15	0.08	lasso	4	0.06	1.8e-04	-5.1	5.2	2.2e-07	0.01	0.24	0.63	FALSE
13	GTEx	Heart Atrial Appendage	RP4-669P10.16	0.08	0.11	lasso	8	0.11	1.3e-05	-5.3	5.2	1.8e-07	-0.01	0.24	0.72	FALSE
14	GTEx	Lung	SMDT1	0.47	0.45	enet	17	0.48	8.7e-41	-5.0	5.1	2.9e-07	0.01	0.35	0.64	FALSE
15	GTEx	Lung	CYP2D7P1	0.20	0.00	lasso	8	0.00	4.2e-01	4.4	6.1	1.2e-09	0.07	0.03	0.56	FALSE
16	GTEx	Muscle Skeletal	SMDT1	0.17	0.26	enet	17	0.28	1.3e-27	-5.1	5.4	5.7e-08	0.02	0.30	0.70	FALSE
17	GTEx	Nerve Tibial	XPNPEP3	0.18	0.02	lasso	14	0.05	9.8e-05	-3.5	5.3	1.3e-07	-0.04	0.46	0.34	TRUE
18	GTEx	Nerve Tibial	RP4-669P10.16	0.06	0.08	lasso	2	0.05	1.2e-04	-5.3	5.3	1.2e-07	-0.02	0.19	0.78	FALSE
19	GTEx	Ovary	RP4-669P10.16	0.24	0.34	lasso	6	0.30	4.0e-08	-5.1	5.3	1.1e-07	0.00	0.24	0.74	FALSE
20	GTEx	Prostate	CYP2D7P1	0.25	0.00	enet	20	0.07	9.2e-03	-5.8	5.4	7.0e-08	0.04	0.02	0.74	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	NAGA	0.13	0.06	lasso	3	0.07	1.4e-04	4.7	5.2	2.4e-07	0.01	0.18	0.19	FALSE
22	GTEx	Spleen	CYP2D7P1	0.17	0.00	lasso	3	0.03	4.8e-02	3.1	5.4	6.6e-08	0.08	0.08	0.16	FALSE
23	GTEx	Stomach	CYP2D7P1	0.22	0.10	lasso	14	0.07	2.7e-04	-5.0	5.9	3.4e-09	0.05	0.22	0.59	FALSE
24	GTEx	Testis	MGAT3	0.47	0.47	enet	26	0.44	3.8e-21	-5.3	5.2	1.9e-07	0.42	0.70	0.30	FALSE
25	GTEx	Testis	RP4-669P10.16	0.35	0.33	enet	28	0.36	8.9e-17	-5.0	5.4	5.3e-08	0.01	0.32	0.68	FALSE
26	GTEx	Thyroid	FAM109B	0.07	0.06	lasso	9	0.05	2.1e-04	-5.1	5.2	1.8e-07	0.01	0.31	0.67	FALSE
27	GTEx	Thyroid	NDUFA6-AS1	0.21	0.16	enet	22	0.19	3.3e-14	-5.0	5.4	6.1e-08	-0.01	0.31	0.69	FALSE
28	GTEx	Vagina	CYP2D6	0.19	0.08	enet	14	0.08	6.8e-03	4.7	-5.4	5.5e-08	-0.04	0.08	0.53	FALSE
29	GTEx	Vagina	SMDT1	0.45	0.51	lasso	4	0.50	3.7e-13	-5.0	5.2	2.3e-07	-0.01	0.29	0.71	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	NAGA	0.08	0.10	lasso	4	0.09	7.3e-12	5.2	5.3	1.4e-07	0.02	0.38	0.62	FALSE
31	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C22orf32	0.10	0.07	enet	10	0.10	3.6e-09	-5.2	5.2	2.6e-07	0.04	0.00	1.00	FALSE
32	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FAM109B	0.03	0.03	enet	3	0.02	5.4e-03	-5.1	5.1	2.9e-07	-0.01	0.01	0.87	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	NAGA	0.04	0.07	enet	3	0.07	1.1e-06	-5.1	5.6	2.2e-08	0.00	0.01	0.99	FALSE
34	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SEPT3	0.03	0.01	blup	44	0.02	1.7e-02	5.2	5.5	4.8e-08	0.00	0.03	0.45	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	C22orf32	0.11	0.16	lasso	3	0.16	3.0e-31	-5.2	5.2	2.1e-07	0.00	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	NAGA	0.03	0.03	lasso	2	0.03	1.2e-07	5.2	5.7	1.4e-08	0.01	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Colon Adenocarcinoma	NAGA	0.09	0.09	enet	7	0.11	7.0e-07	5.1	6.2	7.5e-10	0.00	0.01	0.98	TRUE
38	The Cancer Genome Atlas	Glioblastoma Multiforme	C22orf32	0.14	0.07	lasso	4	0.07	3.1e-03	-5.3	5.3	1.2e-07	-0.02	0.00	0.73	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C22orf32	0.20	0.24	lasso	2	0.24	1.1e-26	-5.2	5.2	1.7e-07	-0.01	0.00	1.00	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NAGA	0.01	0.00	blup	18	0.01	5.4e-02	-4.5	5.4	6.5e-08	0.01	0.01	0.57	FALSE
41	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C22orf32	0.10	0.10	lasso	4	0.11	8.4e-07	-5.2	5.4	7.5e-08	-0.01	0.00	0.99	FALSE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	C22orf32	0.19	0.20	blup	13	0.20	1.9e-22	-5.1	5.3	1.1e-07	-0.02	0.00	0.99	FALSE
43	The Cancer Genome Atlas	Brain Lower Grade Glioma	CENPM	0.05	0.02	blup	42	0.03	1.1e-04	-4.6	-5.1	2.9e-07	-0.08	0.03	0.62	FALSE
44	The Cancer Genome Atlas	Brain Lower Grade Glioma	NAGA	0.04	0.03	enet	16	0.05	6.3e-06	4.4	5.4	6.2e-08	0.02	0.02	0.98	FALSE
45	The Cancer Genome Atlas	Lung Adenocarcinoma	C22orf32	0.16	0.18	enet	4	0.19	2.3e-21	-5.2	5.2	1.8e-07	-0.01	0.00	0.99	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	NAGA	0.02	0.00	blup	18	0.01	1.5e-02	-5.3	5.8	8.3e-09	0.01	0.01	0.77	FALSE
47	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C22orf32	0.15	0.15	lasso	2	0.15	9.6e-07	-5.2	5.2	1.7e-07	0.00	0.00	0.99	FALSE
48	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C22orf32	0.11	0.13	lasso	4	0.12	1.5e-05	-5.3	5.3	1.2e-07	-0.02	0.00	0.98	FALSE
49	The Cancer Genome Atlas	Prostate Adenocarcinoma	NAGA	0.07	0.07	blup	18	0.10	2.0e-10	4.4	5.3	1.4e-07	0.03	0.03	0.97	FALSE
50	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C22orf32	0.34	0.25	lasso	4	0.25	2.0e-09	-5.3	5.3	1.2e-07	-0.02	0.00	0.99	FALSE