Hub : Genes

SNX21

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.0617	0.0311	5.1e-03	0.008	NA	-0.002	NA	0.002	6.8e-02	NA	5.5e-01	NA	2.1e-01
2	GTEx	Brain Cerebellar Hemisphere	0.4050	0.1020	7.9e-04	0.089	NA	0.049	NA	0.042	2.8e-03	NA	2.1e-02	NA	3.0e-02
3	GTEx	Esophagus Mucosa	0.0690	0.0300	5.3e-04	0.089	NA	0.050	NA	0.064	1.4e-06	NA	3.0e-04	NA	4.1e-05
4	GTEx	Muscle Skeletal	0.1474	0.0457	2.0e-07	0.089	NA	0.053	NA	0.076	5.1e-09	NA	5.9e-06	NA	5.8e-08
5	GTEx	Thyroid	0.0910	0.0390	6.5e-04	0.102	NA	0.075	NA	0.103	3.1e-08	NA	2.3e-06	NA	3.0e-08
6	GTEx	Whole Blood	0.0770	0.0370	8.5e-03	0.011	NA	-0.003	NA	-0.002	2.8e-02	NA	8.7e-01	NA	5.2e-01
7	TCGA	Brain Lower Grade Glioma	0.0810	0.0365	3.6e-05	0.009	0.022	0.014	NA	0.033	3.2e-02	1.4e-03	8.7e-03	NA	1.0e-04
8	TCGA	Prostate Adenocarcinoma	0.2141	0.0700	1.9e-05	-0.002	0.039	0.038	NA	0.018	6.4e-01	5.1e-05	7.5e-05	NA	5.3e-03
9	TCGA	Thyroid Carcinoma	0.0690	0.0360	7.8e-04	0.002	0.027	0.018	NA	0.012	2.0e-01	1.1e-03	6.7e-03	NA	2.0e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.4	0.7	2.1	-1.4	0.8	-0.5	0.6	-0.8	0.2	-1.0	-0.8	-0.8
Bipolar Disorder or Schizophrenia	0.6	1.5	4.1	-2.0	0.9	-0.9	1.3	-1.0	0.4	-1.7	-0.7	-1.2
Depressed Affect (Nagel 2018)	2.3	4.8	8.2	-1.9	2.5	-2.7	2.9	-2.1	2.5	-1.0	-1.4	-2.2
Depression (Nagel 2018)	0.4	0.6	1.9	-1.4	1.1	-0.7	1.1	-0.2	0.3	-0.2	-0.5	-0.7
Intelligence (Savage-Jansen 2018)	1.1	3.4	7.5	1.7	-1.7	1.4	-1.5	2.4	-2.7	1.4	0.3	2.4
Neuroticism (Nagel 2018)	1.5	3.6	6.2	-1.8	2.3	-2.1	2.5	-1.9	1.6	-1.3	-0.9	-2.1
Schizophrenia (2018)	0.4	0.8	2.0	-1.4	0.6	-0.8	1.2	-0.7	0.4	-1.4	0.1	-0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	0.9	-0.6	0.2	0.2	0.2	-0.6	0.7	-0.6	-0.5	-1.0
Worry (Nagel 2018)	0.8	1.6	3.5	-1.9	0.7	-1.1	1.3	-1.3	1.9	-1.0	0.2	-1.2
Alzheimer’s Disease (in mother)	2.5	3.0	6.1	-0.9	1.0	-1.4	2.1	-2.1	1.6	-2.5	-0.2	-2.3
Alzheimer’s Disease (in father)	2.3	2.5	4.5	-1.5	1.1	-1.5	1.7	-1.9	0.5	-1.6	-2.1	-1.9
Alzheimer’s Disease (including proxy)	2.3	3.4	7.4	-1.9	0.9	-0.9	1.8	-2.1	2.0	-2.7	-1.1	-2.3
Crohns Disease (2017)	3.4	7.4	19.5	1.9	-4.4	2.6	-2.4	2.6	-4.2	1.6	-0.9	1.7
Irritable Bowel Disease (IBD)	1.0	2.3	5.9	0.5	-2.4	1.3	-1.1	1.7	-2.3	1.2	-0.5	1.2
Ulcerative Colitis (UC)	0.2	0.3	1.2	-0.9	0.4	-0.4	0.3	0.4	-0.0	1.1	0.1	0.6
Major Depression (MDD)	1.2	1.5	4.0	0.4	1.0	-0.7	1.8	-0.8	1.5	-2.0	-0.0	-1.4
Reaction Time	6.0	11.4	21.9	2.8	-4.7	4.2	-4.3	3.2	-3.0	2.9	-0.8	3.0
Verbal and Numeric Reasoning (VNR)	1.8	4.3	13.8	0.5	-1.7	1.6	-1.3	2.7	-3.7	1.6	1.2	2.5
Breast Cancer	1.8	4.4	7.1	0.1	2.5	-2.3	2.1	-2.7	2.5	-2.2	0.7	-2.3
Ovarian Cancer	0.2	0.3	0.9	0.4	0.5	-0.6	0.5	-0.3	0.5	-0.8	0.9	-0.4
Prostate Cancer	1.0	1.5	2.4	-0.5	-1.4	1.1	-1.4	1.3	-0.6	1.5	-1.4	1.2
Age at First Birth	0.6	0.8	4.4	0.6	2.1	-0.4	0.7	0.2	0.9	-0.5	1.0	0.2
Bipolar Disorder (2011)	0.2	0.2	1.0	0.0	-0.1	-0.1	0.0	-0.3	-1.0	-0.9	0.3	-0.1
Body Mass Index (BMI) (2010)	1.5	2.0	4.7	2.2	-0.9	1.4	-1.7	1.6	-1.2	1.4	-0.1	1.3
Coronary Artery Disease (CAD)	1.1	1.3	2.8	-1.4	-1.0	-1.0	1.2	-0.7	1.7	-1.4	-0.7	-1.0
Crohns Disease (2012)	1.8	2.9	6.6	1.2	-2.1	1.3	-1.8	1.3	-1.9	2.6	-1.1	1.3
Mean Putamen Volume	0.4	0.5	2.1	-0.3	0.6	-0.6	-0.3	-0.5	0.7	1.5	0.4	0.5
Fasting Glucose	0.2	0.2	0.7	-0.4	-0.0	-0.0	0.7	-0.1	0.1	-0.8	0.7	-0.5
HbA1C	0.8	0.9	4.4	-0.2	-1.5	0.4	0.3	-0.0	-2.1	-0.7	0.0	-0.9
HDL Cholesterol	6.1	10.2	31.2	1.6	-5.6	3.2	-2.7	3.9	-2.9	1.5	1.0	3.7
LDL Cholesterol	0.3	0.4	1.9	-1.4	0.3	0.4	-0.1	0.1	-1.1	-0.2	0.6	-0.2
Lupus	0.8	1.2	4.0	0.7	-2.0	0.1	0.9	-0.7	0.5	-1.6	-0.5	-1.4
Neuroticism (2016)	2.0	2.8	6.7	-0.4	2.6	-2.2	2.3	-1.3	1.8	-0.2	1.4	-0.9
Primary Biliary Cirrhosis	0.3	0.4	1.4	0.0	-0.7	0.5	-0.2	-0.3	1.2	-0.6	-1.0	-0.6
Rheumatoid Arthritis	0.3	0.4	1.3	-0.4	0.4	-0.8	0.8	-0.6	1.1	0.4	0.2	-0.2
Schizophrenia (2014)	1.1	2.4	6.6	-2.6	0.5	-1.1	1.4	-1.7	0.4	-1.7	-1.6	-1.7
Triglycerides	6.9	11.3	34.1	-1.7	5.8	-3.4	2.9	-3.6	4.7	-0.9	-0.2	-3.0
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.2	-0.6	-0.5	-0.0	0.7	-1.0	-0.3	-1.5	-0.6	-1.4
Ulcerative Colitis	0.5	0.7	2.3	-1.0	-0.1	0.0	-0.3	0.6	0.8	1.5	0.6	1.3
Blood Eosinophil Count	0.2	1.3	4.5	-1.3	0.9	-0.9	0.4	-1.6	2.1	-0.1	-0.9	-0.6
Blood Platelet Count	1.0	11.7	44.6	-2.5	1.9	-2.2	4.2	-2.6	2.0	-6.7	3.1	-2.9
Blood Red Count	2.9	28.4	47.7	4.5	-6.2	6.2	-5.5	6.9	-5.3	3.4	1.8	6.1
Blood White Count	0.8	6.1	10.8	-2.5	2.2	-3.3	3.0	-3.0	1.4	-1.4	2.7	-2.0
Heel T-Score	1.5	11.6	22.8	-1.4	4.8	-3.8	3.2	-4.2	4.4	-2.0	-0.1	-3.7
BMI	0.6	3.4	7.1	0.3	-2.7	1.4	-1.5	2.4	-2.2	2.0	0.2	2.3
Height	0.6	11.9	34.1	2.5	-2.5	4.3	-3.5	5.8	-0.5	3.0	0.5	4.6
Waist Hip Ratio (WHR)	0.9	4.1	7.5	-0.6	2.6	-1.9	2.7	-2.2	0.4	-2.6	0.2	-2.6
Systolic Blood Pressure	1.5	7.7	17.0	-2.2	2.7	-3.6	4.1	-2.9	2.0	-2.6	1.1	-2.7
Smoking Status	0.4	0.9	2.2	-0.8	1.5	-1.4	1.4	-0.2	-0.1	1.0	0.3	-0.1
Allergy or Eczema	2.3	6.0	13.9	1.9	-1.6	3.0	-2.4	2.8	-3.7	1.3	-2.7	1.8
Cardiovascular Disease	3.0	9.9	17.8	-3.7	2.9	-4.1	4.2	-3.2	2.4	-2.7	0.9	-2.9
Hypothyroidism (self reported)	0.1	0.2	1.0	1.0	-0.8	-0.0	-0.0	-0.1	-0.3	0.3	-0.2	-0.0
Respiratory disease	0.6	1.3	4.3	1.2	-2.1	0.7	-0.8	1.0	-1.3	0.9	0.6	1.1
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.5	-0.1	-1.2	-0.2	-0.2	-0.4	-0.4	-0.0	1.1	0.4
Lung FEV1/FVC ratio	1.2	5.9	9.2	-2.9	2.4	-2.8	3.0	-2.6	0.7	-2.6	-0.6	-2.7
Lung FVC	1.4	7.1	15.0	3.5	-3.9	3.1	-2.5	2.8	-3.0	-0.2	-0.0	1.8
Neuroticism	1.9	4.5	7.4	-1.7	2.5	-2.7	2.7	-2.4	2.2	-1.2	0.1	-2.2
Chronotype (morning person)	0.6	1.4	4.1	-1.3	1.7	-0.3	0.7	-0.3	2.0	-0.9	-1.3	-1.0
Hair Pigment	0.2	5.0	11.0	-1.6	1.1	-2.6	3.0	-2.5	0.4	-2.0	-2.1	-3.3
Tanning	0.1	1.1	3.2	-1.5	-0.9	-1.2	0.8	-1.0	0.6	0.1	1.8	-0.1
Hand grip strength (left)	0.5	1.3	4.2	0.5	0.3	0.9	-0.8	2.0	-0.4	0.8	1.4	1.7
Number of treatments/medications taken	1.1	2.0	4.1	-1.1	0.1	-2.0	1.9	-1.9	1.4	-0.8	0.7	-1.7
Average weekly spirits intake	1.8	2.2	3.9	-1.4	1.0	-1.7	1.4	-2.0	0.4	-1.1	-1.9	-1.9
Sensitivity / hurt feelings	1.2	2.1	4.9	-0.4	2.2	-1.7	1.7	-1.4	1.6	-1.1	-0.2	-1.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.2	-1.1	0.4	-0.7	1.0	0.1	0.7	0.1	0.5	-0.5
Hearing difficulty/problems: Yes	1.4	2.1	9.5	1.2	-1.4	0.7	-1.1	1.0	-3.1	1.0	-1.1	1.0
Relative age of first facial hair	0.7	1.5	2.6	1.6	-1.5	1.3	-1.4	1.1	-0.6	1.0	0.6	1.4
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	4.4	-2.1	-0.5	-1.9	1.9	-1.1	1.7	-0.8	0.5	-1.1
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.2	-0.4	0.3	-1.8	1.4	-1.7	1.6	-0.9	0.9	-1.1
Ever had hysterectomy (womb removed)	0.8	0.9	2.9	0.0	1.3	-1.1	1.0	-0.3	1.7	-0.3	0.8	-0.2
Systolic blood pressure, automated reading	0.3	0.9	3.3	-0.9	0.9	-1.4	1.8	-0.5	0.7	-0.5	0.4	-0.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.5	-1.6	0.3	-1.0	0.6	-0.0	1.4	0.3	-0.3	0.3
Angina	0.3	0.4	1.0	0.8	-0.1	-0.3	0.2	-1.0	0.5	-0.5	0.8	-0.7
Medication for hormone replacement therapy	2.4	2.7	4.3	-1.7	0.4	-1.7	1.8	-2.1	1.3	-1.9	1.4	-1.7
Vitamin and mineral supplements	0.7	1.0	2.2	0.8	0.5	-1.3	1.5	-0.3	-1.4	-0.3	-0.9	-1.0
Supplements: Zinc	0.8	0.9	1.7	-1.2	0.7	-1.3	0.3	-1.2	1.3	1.0	0.2	-0.1
Medication: Co-codamol	1.5	1.8	3.8	-1.9	-0.6	-1.6	1.9	-1.3	0.6	-1.3	0.8	-1.2
Medication: Metformin	0.9	1.2	4.4	-0.7	-0.7	-0.2	-0.4	0.5	0.2	1.5	2.1	1.7
Diabetes (father)	0.4	0.4	2.4	0.0	-0.4	-0.4	0.6	0.5	-1.6	-0.4	0.6	0.4
Diabetes (mother)	0.8	1.1	4.4	0.1	-0.4	0.2	0.0	-0.9	-0.8	-2.1	-1.6	-1.0
Severe depression (siblings)	0.5	0.6	3.0	-0.1	1.2	-0.6	0.8	-0.1	1.7	0.2	0.1	0.0
Pack years adult smoking proportion	0.3	0.4	1.4	-0.8	1.2	-0.4	0.6	0.2	-0.2	0.2	-1.1	-0.2
Impedance of leg (right)	0.3	1.6	4.4	0.6	1.0	-0.7	0.7	-1.6	0.3	-1.0	-2.1	-2.1
Leg fat-free mass (left)	0.9	5.0	13.1	0.7	-2.7	2.0	-1.5	3.6	-1.6	1.7	1.5	3.0
Trunk fat percentage	0.2	0.7	1.8	0.4	-1.3	0.6	-0.3	1.3	-0.8	0.9	-0.4	0.9
Hand grip strength (right)	0.2	0.5	1.5	0.5	0.0	0.5	-0.6	1.2	-0.4	0.7	0.4	1.1
Townsend deprivation index at recruitment	0.4	0.6	1.9	-1.2	0.8	-0.3	-0.4	-0.5	-0.5	1.4	0.8	0.1
Current tobacco smoking	0.7	1.2	2.7	-1.4	0.8	-1.3	0.9	0.4	-0.0	1.6	1.6	0.6
Average weekly fortified wine intake	1.1	1.3	4.2	-1.2	0.2	-1.3	0.8	-1.1	1.7	0.2	2.1	-0.1
Maternal smoking around birth	2.9	4.1	7.1	-1.5	2.1	-2.4	2.0	-2.7	1.6	-1.9	-0.7	-2.6
Fed-up feelings	1.2	2.1	5.3	-0.7	2.3	-2.0	1.9	-1.5	0.8	-0.5	-0.5	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	5.2	-1.0	2.3	-1.9	1.8	-1.2	1.3	-0.3	1.4	-0.9
Relative age voice broke	0.2	0.2	1.1	0.8	-1.0	0.1	-0.1	-0.5	0.0	0.1	0.0	-0.4
Taking other prescription medications	0.3	0.5	1.4	-0.2	-0.9	-0.4	0.4	-0.6	1.0	-0.6	1.2	-0.4
Age when periods started (menarche)	0.9	2.2	4.8	1.7	-1.9	2.2	-1.6	1.3	-1.4	-0.6	-1.5	0.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	2.6	0.7	0.9	-1.3	1.4	-0.4	1.6	-0.5	-0.9	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.4	1.0	1.2	0.0	0.5	0.2	-0.2	-1.1	-0.2	-0.4
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.2	1.5	0.6	0.3	-0.7	1.3	1.0	1.8	0.4	1.7
Qualifications: CSEs or equivalent	0.6	0.8	5.5	-0.4	0.8	0.4	-0.0	0.7	0.3	0.3	2.3	0.7
Serious illness, injury or assault to yourself	1.1	1.3	3.8	-0.0	-1.9	0.5	-0.2	1.5	0.6	0.7	1.6	1.3
High blood pressure	2.6	7.1	15.3	-3.9	1.6	-3.6	3.5	-2.7	1.5	-2.0	0.6	-2.6
Hayfever, allergic rhinitis or eczema	1.8	4.0	12.8	2.0	-1.5	1.9	-1.7	1.8	-3.6	1.1	-2.3	0.8
Multivitamins +/- minerals	0.5	0.7	4.2	-0.8	0.4	0.3	-0.8	-0.6	2.0	0.3	0.3	0.1
Stomach or abdominal pain in last month	1.4	1.7	3.4	-1.1	0.5	-1.2	1.7	-1.0	1.8	-1.5	-1.1	-1.4
Supplements: Glucosamine	1.5	2.0	10.2	-1.2	-1.3	-0.2	-0.4	-0.4	1.2	1.4	3.2	0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.1	-1.5	-0.3	0.4	0.1	0.2	-0.5	-0.4	-1.4	-0.2
Medication: Atenolol	2.5	3.1	7.3	-2.7	1.6	-1.9	1.6	-2.3	1.1	-1.1	0.3	-2.1
Medication: Levothyroxine sodium	0.2	0.4	0.8	0.9	-0.7	-0.8	0.7	-0.7	-0.1	-0.2	0.1	-0.9
Sitting height	0.8	5.8	12.7	2.1	-2.2	3.3	-2.6	3.6	-2.1	0.3	1.2	2.6
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	-0.1	0.2	0.7	-0.2	0.3	-0.3	0.1	0.6	-0.0
High blood pressure (mother)	0.8	1.1	4.1	0.4	-0.5	1.4	-0.3	1.2	0.6	-1.3	-2.0	-0.2
Body mass index (BMI)	0.1	0.5	1.2	-0.9	-0.5	-0.9	1.1	0.3	-0.6	0.4	0.7	0.4
Impedance of leg (left)	0.1	0.6	1.9	0.7	0.9	-0.1	-0.1	-0.9	0.0	-0.4	-1.4	-1.1
Leg predicted mass (left)	0.9	4.6	12.4	0.7	-2.6	2.0	-1.5	3.5	-1.6	1.6	1.4	2.9
Trunk fat mass	0.4	1.6	4.1	0.4	-1.9	1.0	-0.5	2.0	-1.0	1.1	0.2	1.6
Waist circumference	0.1	0.4	1.0	-0.8	-0.7	-0.5	1.0	0.6	-0.7	0.0	0.6	0.3
Number of incorrect matches in round	1.3	2.2	7.0	-1.9	1.0	-1.1	0.9	-1.7	2.6	-1.0	-0.2	-1.3
Past tobacco smoking	0.4	0.7	2.3	0.2	-1.3	0.3	-1.0	0.2	0.8	0.2	1.5	0.9
Alcohol usually taken with meals	1.2	2.0	6.8	-0.7	-0.3	-0.3	0.5	-1.7	1.1	-1.7	-2.6	-1.7
Nervous feelings	0.5	0.9	2.9	-0.7	1.7	-0.7	0.7	-0.6	-0.0	-0.3	1.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	6.5	-1.0	1.6	-2.1	2.5	-1.2	0.3	-1.1	1.2	-1.4
Hearing difficulty/problems with background noise	0.8	1.2	4.9	0.4	-0.8	0.3	-0.9	1.1	-2.2	1.2	-0.7	1.3
Hair/balding pattern: Pattern 2	0.4	0.5	1.3	0.9	-0.2	-0.1	-0.1	-1.1	-1.1	-0.7	-0.1	-1.0
Had menopause	0.7	0.8	2.8	0.0	-0.8	-0.2	-0.2	0.5	1.0	1.7	1.4	0.9
Had other major operations	0.2	0.2	0.6	-0.3	0.1	-0.5	0.3	0.1	0.8	0.3	0.5	0.5
Forced vital capacity (FVC)	3.0	11.4	19.0	3.9	-4.3	3.8	-3.4	4.4	-3.2	1.3	0.9	3.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	2.5	1.2	1.6	-0.5	0.5	-0.9	0.6	-1.1	0.2	-1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	3.2	-1.4	0.7	0.3	0.4	0.5	0.9	-0.6	1.8	0.1
Qualifications: None of the above	1.4	3.0	7.3	-1.9	1.9	-1.9	1.2	-2.2	2.7	-0.8	0.8	-1.1
Financial difficulties in last 2 years	1.0	1.4	8.2	-0.3	1.2	-0.8	1.2	0.1	0.7	-0.4	2.9	0.2
Mouth/teeth dental problems	0.9	1.4	4.1	2.0	-1.4	1.5	-1.6	0.8	0.8	-0.3	0.1	0.8
Heart attack	1.3	1.7	3.2	-1.2	0.3	-1.8	1.8	-1.7	0.3	-1.2	-0.3	-1.6
Allergy	1.0	2.4	7.3	-0.9	1.6	-1.7	1.6	-1.6	2.7	-1.1	0.9	-1.0
Pain all over the body in last month	0.6	0.7	2.0	0.7	0.2	0.5	-1.4	0.2	1.0	0.9	0.7	1.0
Diabetes (self-reported)	0.4	0.6	1.5	-1.0	-1.2	-0.5	0.3	-0.5	-0.6	-0.0	1.2	0.3
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	9.4	1.6	-0.4	2.1	-1.7	0.8	-3.1	-0.4	0.4	0.5
Medication: Ramipril	1.0	1.3	3.5	0.2	-0.8	-1.3	0.7	-1.9	-0.8	-0.6	1.6	-1.3
Medication: Simvastatin	2.6	3.8	8.1	-2.2	1.8	-2.8	2.9	-2.2	0.2	-1.2	0.5	-2.0
Fluid intelligence score	2.4	4.9	12.9	0.8	-2.4	2.2	-1.7	2.9	-3.6	1.5	1.0	2.3
Illnesses of siblings	0.5	0.8	2.8	0.3	-1.3	1.0	-0.9	0.3	-0.6	0.1	-1.7	0.2
Neuroticism score	1.8	3.8	6.1	-1.7	2.4	-2.4	2.5	-2.0	2.1	-1.0	-0.5	-2.0
Weight	0.5	2.3	6.7	0.2	-1.9	1.0	-0.5	2.6	-1.0	1.3	1.1	2.2
Impedance of arm (right)	0.3	1.4	3.6	1.7	-0.8	1.9	-1.9	-0.0	0.3	-0.0	-1.3	-0.1
Arm fat percentage (right)	0.2	0.7	1.7	0.1	-1.3	0.3	-0.2	0.8	-1.3	0.9	0.6	1.0
Trunk fat-free mass	0.9	5.3	14.5	0.6	-2.2	1.9	-1.5	3.8	-1.7	1.7	2.3	3.2
Hip circumference	0.4	1.6	3.6	0.0	-1.8	0.6	-0.4	1.9	-0.6	1.7	0.9	1.8
Time employed in main current job	0.9	1.0	2.4	-1.5	0.2	-1.0	0.4	-1.5	1.2	-0.6	-0.8	-0.9
Alcohol intake versus 10 years previously	0.2	0.2	1.2	0.0	-0.5	0.3	-0.1	0.2	-0.6	-0.0	1.1	0.5
Father’s age at death	0.7	1.0	3.0	-1.1	1.0	-0.0	0.1	-0.1	1.7	0.7	-1.7	-0.5
Worrier / anxious feelings	1.5	2.9	11.2	-1.3	1.5	-1.8	1.4	-1.4	3.3	-0.5	1.7	-0.7
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	5.9	-2.4	2.2	-1.6	2.1	-1.1	1.7	-1.0	-2.0	-1.4
Falls in the last year	0.3	0.4	1.0	-0.9	-1.0	-0.2	0.6	0.1	-0.8	-0.3	-0.6	-0.3
Hair/balding pattern: Pattern 3	0.8	1.2	2.6	-1.6	1.3	-0.5	1.3	-0.7	0.4	-1.4	-0.2	-1.3
Number of live births	0.7	1.0	2.7	0.4	1.3	-1.3	0.7	-0.5	1.7	0.6	1.1	0.3
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	10.4	3.2	-2.9	2.7	-2.1	3.1	-2.3	0.1	0.8	2.1
Pulse rate	0.3	0.5	1.0	-0.3	0.9	-0.5	1.0	0.0	0.8	-0.4	-1.0	-0.6
Happiness	0.5	0.7	2.7	-0.6	0.4	0.2	-0.2	1.0	0.5	0.7	1.6	0.9
Noisy workplace	0.8	1.0	2.0	-1.4	-0.8	-0.6	0.9	-0.9	0.6	-1.4	1.2	-0.5
Qualifications: A levels/AS levels or equivalent	5.3	11.6	17.1	3.5	-3.4	3.9	-4.0	3.5	-4.1	3.0	0.3	3.3
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	5.4	2.3	0.0	0.8	-0.6	1.1	2.2	-0.2	0.3	0.6
Mouth/teeth dental problems: Dentures	0.8	1.4	7.3	-0.8	0.7	-1.6	0.7	-0.1	-0.7	2.7	-0.2	0.7
Asthma	0.3	0.6	1.4	0.3	-1.2	0.3	-0.6	0.4	-0.6	0.9	1.1	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.3	0.6	1.1	0.2	0.0	0.1	0.8	-0.4	-0.0	-0.1
Medication: Cholesterol lowering	3.3	5.2	9.2	-2.4	2.2	-3.0	2.8	-2.8	0.7	-1.5	-1.1	-2.6
Depression (self-reported)	0.9	1.0	4.2	-0.5	1.0	-0.1	-0.3	0.6	0.6	1.1	2.1	1.2
Medication: Lansoprazole	0.1	0.2	0.7	0.3	0.6	0.1	-0.2	0.1	0.5	-0.1	0.8	0.1
Prospective memory result	0.9	1.1	6.6	0.3	0.4	0.6	-0.9	0.0	2.6	0.1	1.4	0.5
Lung cancer (father)	1.1	1.3	3.5	-0.2	1.4	-1.1	1.0	-1.4	-0.2	-1.0	-0.7	-1.9
Illnesses of mother	0.9	1.1	3.9	-0.8	0.5	-2.0	1.0	-1.4	-0.1	1.3	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.6	13.9	2.9	-3.0	3.3	-2.4	3.7	-2.5	0.1	0.2	2.3
Pulse wave Arterial Stiffness index	1.9	2.3	4.5	2.0	-1.0	1.0	-1.0	2.1	-0.1	2.1	0.5	2.0
Impedance of arm (left)	0.2	0.9	2.6	1.3	-0.2	1.0	-0.9	-0.7	0.9	-0.5	-1.6	-0.8
Arm fat mass (right)	0.4	1.5	3.1	0.1	-1.5	0.6	-0.4	1.8	-1.4	1.1	1.1	1.7
Trunk predicted mass	0.8	4.8	13.5	0.5	-2.1	1.8	-1.3	3.7	-1.6	1.6	2.3	3.1
Standing height	1.1	11.4	27.3	2.8	-3.5	4.5	-3.7	5.2	-1.5	1.7	0.8	3.9
Length of working week for main job	0.8	0.9	2.3	-1.4	0.2	-0.3	0.8	-0.8	0.0	-1.1	-1.2	-1.5
Exposure to tobacco smoke at home	0.7	0.8	1.8	-1.4	-0.2	-1.2	0.6	-0.5	0.7	0.9	1.1	-0.1
Breastfed as a baby	1.4	1.7	5.9	2.4	-0.9	1.5	-1.2	1.0	-1.4	0.4	1.2	0.9
Tense / ‘highly strung’	1.1	1.8	3.5	-0.9	0.3	-1.9	1.8	-1.6	1.2	-1.3	-0.9	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	6.2	-0.9	0.8	-0.6	0.7	-0.6	2.5	-0.7	2.0	-0.3
Hair/balding pattern: Pattern 4	0.1	0.3	0.6	-0.8	0.6	-0.4	0.3	0.1	0.5	0.3	0.7	0.4
Birth weight of first child	0.8	1.5	6.0	0.3	-0.9	-0.3	0.8	-0.5	-2.5	-0.9	-1.6	-1.5
Peak expiratory flow (PEF)	0.2	0.5	1.7	1.3	-0.7	0.3	-0.5	0.9	0.6	0.3	0.4	0.7
Pulse wave reflection index	4.5	5.6	10.3	3.2	-0.9	2.5	-2.4	2.9	-1.6	1.8	1.6	3.2
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.5	0.5	1.3	0.2	-0.6	0.0	1.6	0.8	0.3	0.1
Loud music exposure frequency	1.0	1.1	5.3	0.3	-2.3	0.5	-0.8	0.2	-1.0	0.7	1.3	0.4
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	4.8	1.6	-0.2	1.5	-1.4	1.5	-2.2	1.2	-1.4	0.9
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	4.1	-1.9	-0.7	-1.1	1.8	-1.2	-0.6	-2.0	0.1	-1.7
Blood clot in the leg (DVT)	0.7	0.9	2.0	-0.1	-0.9	1.4	-1.0	1.2	-1.3	0.3	0.0	0.6
Medication: Paracetamol	0.2	0.3	1.1	0.6	0.3	-0.5	0.2	-1.0	0.1	0.0	0.3	-1.0
Headache pain in last month	0.3	0.6	1.1	-0.5	0.6	-1.0	0.9	-0.5	1.0	0.2	1.0	-0.4
Medication for cholesterol, blood pressure or diabetes	5.0	8.2	14.9	2.2	-2.4	3.9	-3.6	3.8	-1.4	2.4	1.1	3.6
Glaucoma (self-reported)	0.7	0.8	3.7	-0.2	0.8	-1.9	1.0	-0.9	0.1	0.6	0.7	-0.3
Gout (self-reported)	1.0	1.4	4.3	0.6	-2.1	1.3	-0.5	1.5	-1.0	0.2	1.1	1.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	3.2	1.6	-1.8	0.4	-0.5	0.5	-0.8	0.7	0.1	0.5
Medication: Amlodipine	2.8	3.9	10.8	-1.1	0.1	-3.3	2.9	-2.3	2.2	-1.0	0.7	-2.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.7	0.1	0.6	-1.3	1.1	-0.5	-0.3	0.5	0.7	0.0
Birth weight	1.2	2.7	6.9	2.0	-0.0	2.0	-1.2	2.4	-2.6	-0.1	0.9	1.3
Chronic bronchitis/emphysema (mother)	0.8	1.0	3.4	0.6	-0.6	-0.1	0.4	-0.2	-1.8	-0.8	1.9	-0.7
High blood pressure (siblings)	0.1	0.1	0.5	-0.1	0.4	-0.0	0.1	-0.0	0.2	-0.3	0.7	-0.3
Forced vital capacity (FVC), Best measure	4.1	14.9	30.6	3.7	-4.4	5.0	-4.1	5.5	-3.2	1.4	0.4	4.1
Body fat percentage	0.1	0.4	1.3	0.1	-1.1	0.0	0.1	0.7	-0.8	0.9	-0.2	0.6
Leg fat percentage (right)	0.2	0.8	2.1	-1.4	-0.4	-1.3	1.5	-0.8	-0.1	-0.0	-0.3	-0.8
Arm fat-free mass (right)	0.7	3.6	11.4	0.4	-1.8	1.4	-0.8	3.4	-1.4	1.3	2.0	2.7
Exposure to tobacco smoke outside home	0.7	0.9	3.5	-0.9	-1.5	-0.6	-0.7	-0.4	-0.4	1.9	-0.4	0.6
Comparative body size at age 10	0.5	1.3	8.5	-0.6	1.3	-0.5	-0.0	-0.4	2.9	0.5	0.6	0.4
Number of full brothers	0.5	0.6	2.6	0.2	1.6	-1.0	0.3	-0.6	0.0	0.8	0.6	-0.2
Worry too long after embarrassment	0.8	1.3	2.1	1.3	1.0	1.4	-1.1	1.4	-0.8	1.1	-1.1	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.8	-0.8	0.3	0.4	-0.0	0.1	0.1	-0.9	0.3	-0.1
Wheeze or whistling in the chest in last year	0.8	1.5	4.1	-0.2	-0.5	0.1	-0.4	1.4	0.2	1.9	2.0	1.8
Number of children fathered	1.5	1.7	4.6	-0.6	2.1	-1.6	0.9	-1.8	1.4	-0.3	0.2	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.2	0.9	1.1	-1.4	1.5	-0.9	0.5	-0.5	0.5	-0.5
Age at first live birth	0.8	1.4	3.6	0.5	-1.3	1.3	-0.6	1.6	-1.9	0.3	-1.3	0.7
Pulse wave peak to peak time	1.7	2.0	5.2	-1.8	0.8	-0.7	0.9	-1.8	-0.1	-2.3	-0.7	-2.0
Health satisfaction	2.8	3.6	7.3	-1.7	1.1	-2.2	2.7	-1.9	1.0	-2.3	-0.1	-2.5
Shortness of breath walking on level ground	0.9	1.1	3.3	-1.8	1.1	-1.5	1.8	0.0	0.1	-0.1	-0.3	-0.3
Qualifications: College or University degree	4.4	14.0	24.2	3.8	-3.7	4.5	-3.8	4.6	-4.9	2.1	0.4	3.7
Eye problems/disorders: None of the above	0.6	0.7	1.4	1.1	-0.4	1.2	-0.4	0.8	-0.5	-0.8	1.1	0.4
Mouth/teeth dental problems: Loose teeth	1.3	1.6	3.0	0.2	1.5	-1.3	1.7	-1.1	0.1	-0.8	-1.7	-1.6
Emphysema/chronic bronchitis	0.7	0.8	5.1	-2.3	0.3	-0.0	0.3	-0.5	0.7	-0.6	-0.7	-0.4
Medication for pain relief, constipation, heartburn	0.7	1.2	2.4	0.6	-0.9	1.2	-1.2	1.4	-1.3	0.6	0.7	1.5
Neck or shoulder pain in last month	1.0	1.4	3.4	-0.0	1.8	-1.7	1.5	-0.9	1.4	0.3	0.8	-0.8
Medication: Blood pressure	3.7	6.5	13.7	-2.7	0.9	-3.7	3.3	-3.3	0.6	-2.0	-0.7	-3.2
Angina (self-reported)	0.2	0.3	0.9	0.9	-0.1	-0.2	0.0	-0.8	0.6	-0.3	1.0	-0.3
Migraine (self-reported)	0.3	0.4	1.0	-0.9	-0.8	-0.4	0.6	-0.3	0.6	0.2	1.0	-0.2
Medication: Ibuprofen	0.1	0.1	0.3	0.2	0.0	0.4	-0.5	0.5	-0.3	0.4	0.0	0.5
Medication: Allopurinol	0.8	1.1	3.0	-0.4	-1.2	1.5	-0.5	1.7	-1.5	0.3	0.1	0.9
Medication: Omeprazole	1.2	1.5	4.6	-1.1	0.9	-0.2	1.0	-0.1	1.2	-1.6	-2.1	-1.2
Medication: Seretide 50 evohaler	0.2	0.2	0.9	-0.0	0.4	0.3	-0.3	-0.3	0.9	-0.2	1.0	-0.2
Mean time to correctly identify matches	4.0	7.7	18.6	2.4	-4.3	3.2	-3.2	2.5	-2.8	2.3	0.0	2.3
Heart disease (mother)	0.7	0.9	2.0	-0.1	-1.0	1.4	-1.4	0.9	0.6	0.3	-1.1	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.4	4.0	7.6	-1.6	0.9	-2.0	2.0	-2.4	1.4	-1.8	-2.5	-2.8
Whole body fat mass	0.3	1.2	2.9	0.2	-1.6	0.6	-0.3	1.7	-1.2	1.1	0.5	1.4
Leg fat mass (right)	0.2	0.9	2.4	-0.8	-1.5	-0.0	0.3	1.2	-1.2	1.0	0.5	1.0
Arm predicted mass (right)	0.8	3.9	12.5	0.1	-2.0	1.4	-0.9	3.5	-1.6	1.6	1.8	2.8
Pulse rate, automated reading	1.1	3.6	8.8	-1.7	2.0	-2.3	3.0	-1.4	1.4	-1.8	-0.6	-2.0
Alcohol intake frequency.	1.0	2.3	14.5	-0.9	0.6	0.2	-0.5	-0.1	1.9	1.0	3.8	0.7
Comparative height size at age 10	0.8	4.2	9.6	1.4	-2.6	2.1	-1.7	3.1	-0.5	1.5	1.5	2.7
Number of full sisters	0.1	0.1	0.4	0.2	0.5	0.3	0.1	0.1	-0.6	-0.1	-0.4	-0.2
Suffer from ‘nerves’	0.2	0.2	0.9	-0.2	0.1	0.6	0.1	0.6	-0.6	-0.2	1.0	0.2
Overall health rating	2.3	5.0	12.7	-2.2	2.1	-3.2	3.6	-1.8	1.4	-1.5	0.5	-2.1
Chest pain or discomfort	1.6	2.3	4.7	-1.1	1.0	-1.7	1.9	-1.8	0.2	-1.8	-0.6	-2.2
Had major operations	0.2	0.3	1.0	-0.3	-1.0	-0.6	-0.0	-0.6	0.4	0.7	0.1	0.0
Age at last live birth	0.3	0.5	1.3	0.3	-0.3	0.2	0.3	1.1	-1.1	0.6	-1.0	0.6
Family relationship satisfaction	1.5	1.9	2.7	-1.6	1.5	-1.5	1.6	-1.3	1.6	-1.0	0.2	-1.3
Leg pain on walking	1.1	1.4	4.7	-0.3	2.2	-1.1	1.2	-0.8	1.8	-0.4	0.6	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.5	-0.6	0.6	-1.2	0.6	-1.1	0.4	0.3	0.1	-0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.7	-0.4	1.2	-0.6	0.4	-0.1	1.3	0.3	-0.0	0.0
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	5.2	-0.6	1.5	-0.7	-0.2	-1.5	-1.4	0.7	-2.3	-1.0
Medication: Aspirin	1.0	1.3	3.1	-0.8	0.4	-1.6	1.8	-1.3	0.8	-0.6	-0.6	-1.4
Supplements: Vitamin C	0.9	1.1	2.9	-0.3	-0.6	1.7	-1.5	1.4	-0.1	0.5	-0.3	1.4
Knee pain experienced in last month	1.0	1.6	8.1	-0.6	0.6	-1.3	1.4	-0.5	1.4	-0.1	2.9	-0.1
Hypertension (Self-reported)	3.1	8.6	16.4	-3.9	1.9	-4.1	4.0	-3.1	1.6	-2.4	0.4	-3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	2.1	-0.4	0.4	-0.3	-0.0	0.3	1.5	0.5	0.1	0.5
Illnesses of father: Heart disease	0.6	0.8	1.9	-0.6	1.0	-1.3	1.4	-0.6	1.1	-0.2	0.6	-0.1
Illnesses of siblings: Diabetes	0.3	0.3	1.4	0.1	-0.1	-0.2	0.7	0.1	-0.7	-0.5	-1.2	-0.4
Smoking status: Previous	0.7	1.1	4.7	0.3	1.9	-0.1	0.8	-0.1	-0.3	-0.4	-2.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	4.2	8.8	16.3	1.9	-2.7	2.7	-3.2	4.0	-2.0	3.2	2.0	4.0
Whole body fat-free mass	1.0	5.6	15.5	0.7	-2.5	2.0	-1.6	3.9	-1.7	1.9	2.1	3.4
Leg fat-free mass (right)	1.2	6.3	15.8	0.9	-2.8	2.4	-1.9	4.0	-1.7	2.0	1.9	3.5
Arm fat percentage (left)	0.1	0.3	1.1	-0.2	-1.1	-0.1	0.3	0.4	-0.8	0.6	0.3	0.5
Average weekly red wine intake	1.2	1.7	8.2	-0.9	1.1	-0.6	0.9	-0.8	-0.7	-0.7	-2.9	-1.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.6	-0.9	-0.0	-1.3	1.0	-1.3	1.1	-0.0	-0.4	-0.6
Mood swings	2.3	4.1	10.6	-1.7	1.9	-2.8	2.7	-1.5	3.3	-0.1	0.7	-1.4
Loneliness, isolation	1.2	1.7	5.1	-2.3	1.2	-1.9	1.7	-0.9	0.2	0.5	0.8	-0.6
Long-standing illness, disability or infirmity	0.7	1.1	2.9	-1.2	0.1	-1.7	1.3	-1.2	1.1	-0.1	0.2	-1.1
Ever had bowel cancer screening	2.4	2.8	5.6	-1.0	0.6	-1.5	1.7	-2.0	1.9	-2.4	-0.9	-2.2
Diabetes diagnosed by doctor	0.3	0.5	1.6	-0.6	-1.3	-0.0	-0.3	0.1	-0.3	0.7	1.0	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	3.4	-0.4	0.8	-0.7	0.3	-1.1	1.8	-0.2	1.1	-0.2
Friendships satisfaction	0.8	0.9	2.6	-1.5	1.6	-0.4	0.8	-0.6	0.8	-1.0	-0.4	-0.9
Qualifications: nursing, teaching	1.9	3.0	12.8	0.8	-3.6	0.9	-1.2	1.8	-1.7	1.4	0.4	1.7
Commuting to job workplace: Walk	1.1	1.1	5.5	2.4	-0.1	0.9	-1.2	0.7	-0.1	1.1	0.2	0.9
Eye problems/disorders: Cataract	1.1	1.3	5.6	-0.6	0.5	-0.6	0.5	-1.1	0.9	-0.8	-2.4	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.9	-0.9	1.4	-0.2	0.5	-0.0	0.1	-0.3	0.3	0.0
Medication for cholesterol	2.8	4.2	6.8	2.6	-1.1	2.6	-2.1	2.4	-2.1	1.1	-2.3	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.8	0.6	-0.1	-0.2	-0.7	0.5	-0.6	-0.0	-0.2
Back pain experienced in last month	2.0	2.9	9.4	-1.0	1.0	-2.3	1.7	-1.9	3.1	-0.4	0.8	-1.4
Mineral and other dietary supplements	1.5	2.0	4.5	2.0	1.2	0.9	-0.4	2.1	-1.6	0.6	-1.9	1.0
Breast cancer (self-reported)	0.9	1.1	4.8	-0.1	1.8	-0.5	0.7	0.4	0.9	0.2	2.2	0.4
Asthma (self-reported)	0.2	0.4	0.8	-0.1	-0.9	-0.0	-0.4	0.2	-0.6	0.7	0.8	0.7
Osteoporosis (self-reported)	0.4	0.5	1.4	-0.0	-1.2	0.7	-0.7	-0.5	1.1	-0.5	-0.8	-0.3
Osteoarthritis (self-reported)	0.5	0.6	2.4	-0.6	0.0	-1.2	0.9	-0.6	1.6	0.2	-0.1	-0.3
Medication: Aspirin	0.5	0.7	2.4	-0.2	0.2	-1.5	1.5	-0.8	0.3	-0.1	0.4	-0.8
Medication: Gliclazide	0.6	0.7	2.0	-0.9	0.7	-0.6	0.3	-0.9	1.3	-0.2	1.4	-0.0
Illnesses of father: None of the above (group 1)	0.2	0.3	1.1	0.2	0.6	0.5	-0.8	-0.2	0.1	0.1	-1.0	-0.1
Smoking status: Current	0.8	1.2	3.3	-1.5	0.4	-1.3	0.9	0.3	0.3	1.6	1.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	7.6	2.2	-2.0	1.3	-1.5	2.3	-2.8	1.0	0.8	2.3
Whole body water mass	1.0	5.8	15.8	0.7	-2.4	2.1	-1.7	4.0	-1.8	1.9	2.1	3.4
Leg predicted mass (right)	1.2	6.2	15.7	0.9	-2.7	2.3	-1.9	4.0	-1.6	2.0	1.9	3.5
Arm fat mass (left)	0.3	1.3	3.1	0.3	-1.4	0.5	-0.2	1.7	-1.4	1.1	0.7	1.5
Number of self-reported non-cancer illnesses	2.3	4.0	8.1	-2.1	2.0	-2.8	2.3	-2.0	2.8	0.0	1.2	-1.1
Average weekly champagne plus white wine intake	2.5	3.4	6.3	1.7	-1.7	2.3	-2.5	1.7	-2.3	0.5	1.3	1.9
Miserableness	0.9	1.6	3.6	-0.1	1.5	-1.9	1.9	-0.9	1.7	-0.3	-0.4	-1.0
Guilty feelings	0.5	0.7	2.7	0.3	1.6	-0.9	1.2	-0.1	-0.6	0.0	0.7	-0.4
Wears glasses or contact lenses	0.4	0.5	2.4	0.6	0.4	0.8	-0.5	0.3	1.6	0.0	-0.1	0.5
Ever taken oral contraceptive pill	0.8	0.9	2.7	1.2	-1.0	0.1	0.4	0.8	-1.7	-0.2	-1.5	0.2
Hearing aid user	0.9	1.0	2.2	-1.3	-0.5	-1.4	1.5	-1.1	0.1	-0.6	-0.6	-1.1
Mother’s age at death	0.5	0.7	1.9	0.3	-1.0	1.1	-1.4	0.3	0.1	0.7	-1.1	0.2
Financial situation satisfaction	0.3	0.4	1.3	-1.0	1.1	-0.4	0.3	-0.1	-1.1	0.2	0.3	-0.3
Tinnitus: Yes, now most or all of the time	1.1	1.3	6.2	1.2	-0.9	1.5	-0.9	0.6	-2.5	-0.1	-0.1	-0.1
Commuting to job workplace: Public transport	0.6	0.7	3.7	0.4	-1.9	0.6	-0.6	-0.1	-1.0	0.0	-0.6	-0.1
Eye problems/disorders: Glaucoma	0.8	1.0	4.5	-0.7	0.6	-2.1	1.1	-1.0	0.7	0.9	0.5	-0.2
Medication: Blood pressure	1.1	2.1	3.6	-1.8	1.4	-1.7	1.5	-1.4	1.9	-0.6	1.5	-0.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	3.2	-0.8	1.8	0.3	-0.2	0.3	0.2	0.1	0.9	0.5
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.7	-1.6	-0.9	-0.2	0.2	-1.5	1.0	-0.5	1.6	-0.9
High cholesterol (Self-reported)	1.7	3.0	5.8	-1.1	2.4	-2.2	2.1	-1.7	1.5	-0.9	1.7	-1.3
Medication: Bendroflumethiazide	0.8	1.2	4.3	-1.0	0.6	-2.1	1.2	-1.1	1.1	0.7	-0.2	-0.4
Medication: Paracetamol	0.2	0.2	1.0	1.0	-0.3	-0.2	0.1	-0.5	-0.3	-0.0	0.5	-0.7
Medication: Lisinopril	0.2	0.2	0.9	-0.1	0.2	-1.0	0.6	-0.1	0.1	0.3	0.6	0.5
Medication: Atorvastatin	0.3	0.4	1.3	-0.1	-0.5	-0.0	-0.4	0.7	0.3	1.1	0.6	1.0
Illnesses of father: High blood pressure	1.5	1.8	5.5	-1.3	0.8	-2.4	1.9	-1.5	1.2	-0.4	0.3	-0.9
Alcohol drinker status: Never	2.2	2.6	4.7	-1.5	0.7	-2.2	2.0	-2.0	0.8	-1.2	1.8	-1.6
Ever smoked	0.4	0.7	2.8	0.0	0.5	0.1	0.6	-0.2	-1.7	-0.6	-1.1	-1.1
Basal metabolic rate	1.0	5.5	14.8	0.7	-2.5	1.9	-1.5	3.9	-1.7	1.9	2.1	3.3
Leg fat percentage (left)	0.2	0.6	2.1	-1.5	-0.2	-1.2	1.2	-0.5	0.2	0.2	0.2	-0.3
Arm fat-free mass (left)	1.1	5.8	15.7	0.8	-2.4	1.9	-1.4	4.0	-2.0	2.0	2.2	3.3
Number of operations (self-reported)	0.9	1.4	2.2	0.1	0.9	-1.4	1.3	-1.3	1.5	-1.2	-0.8	-1.3
Average weekly beer plus cider intake	0.5	0.8	2.6	0.5	-0.2	-0.2	0.3	1.6	-0.7	1.2	1.1	0.9
Irritability	1.4	2.4	4.4	-0.2	1.1	-2.1	2.1	-1.8	-0.1	-1.3	-1.8	-1.9
Risk taking	0.3	0.4	2.0	-0.4	-0.8	-0.1	-0.2	-0.3	-0.6	0.0	-1.4	-0.4
Ever had prostate specific antigen (PSA) test	1.8	2.0	4.3	-1.4	2.0	-1.7	0.7	-1.7	2.1	-0.2	1.1	-0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.8	-0.6	-0.6	0.9	-0.6	-0.2	0.6	-0.3	-1.3	-0.6
Age started oral contraceptive pill	0.9	1.1	4.6	-2.1	-0.3	-0.9	1.4	-0.3	1.4	-0.4	-0.0	-0.5
Diastolic blood pressure, automated reading	0.2	0.7	2.2	-1.3	0.3	-0.6	1.5	-0.3	-0.1	-1.0	-0.7	-0.6
Ever depressed for a whole week	0.8	0.9	2.4	-0.6	1.6	0.4	0.2	0.1	1.3	-1.1	1.6	0.2
Unable to work because of sickness or disability	0.9	1.2	3.6	-1.2	-0.6	-1.9	1.3	-0.7	0.2	1.0	1.4	0.0
Commuting to job workplace: Cycle	1.6	1.9	8.1	1.4	-1.0	0.6	-1.3	0.6	-0.6	1.4	2.9	1.2
Myopia	0.3	0.4	2.0	0.2	0.1	0.7	-0.3	-0.4	-0.6	-1.4	-0.1	-0.8
Vascular/heart problems diagnosed by doctor	2.3	6.3	11.6	3.4	-0.9	3.4	-3.4	2.7	-1.4	2.0	-0.8	2.7
Cholesterol lowering medication	1.9	2.8	5.3	-1.4	2.0	-2.3	1.9	-1.6	1.4	-0.4	2.2	-0.8
Medication: Omeprazole (e.g. Zanprol)	2.0	2.5	4.4	-1.1	1.2	-1.0	1.7	-0.9	1.9	-1.9	-2.1	-1.8
Pain experienced in last month	0.5	0.9	3.1	0.5	-1.0	0.7	-0.2	0.4	-1.7	-1.0	-1.4	0.0
Supplements: Calcium	0.5	0.5	2.0	-1.4	-1.0	-0.1	-0.1	-0.8	0.5	-0.2	0.7	0.0
Basal cell carcinoma (self-reported)	0.8	0.9	4.2	0.9	2.1	-0.7	0.9	-0.5	0.6	-0.8	0.9	-0.5
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.0	-1.2	0.3	-1.7	1.7	-1.5	0.4	-0.9	-0.4	-1.4
Deep venous thrombosis (DVT) (self-reported)	1.1	1.5	3.0	0.5	-1.0	1.7	-1.5	1.6	-1.5	0.7	0.4	1.1
Heart disease (siblings)	1.2	1.4	7.0	-0.1	1.6	-1.3	0.9	-0.9	0.0	0.5	2.6	-0.1
Alcohol drinker status: Previous	2.1	2.4	4.7	0.1	0.8	2.0	-1.8	1.7	1.2	1.3	2.2	1.7
Pack years of smoking	0.6	0.8	3.1	-0.8	1.4	-0.8	0.7	-0.4	0.2	0.3	-1.8	-0.6
Impedance of whole body	0.2	0.8	2.6	1.0	0.5	0.5	-0.5	-0.9	0.6	-0.7	-1.6	-1.2
Leg fat mass (left)	0.2	0.9	2.0	-0.8	-1.4	0.0	0.1	1.2	-0.9	1.1	0.7	1.2
Arm predicted mass (left)	1.0	5.3	15.1	0.6	-2.2	1.8	-1.2	3.9	-2.1	1.9	2.1	3.2