TWAS hub - ZSWIM1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue (Male)	0.1486	0.1032	5.7e-02	-0.013	NA	-0.011	NA	-0.013	9.8e-01	NA	7.1e-01	NA	9.7e-01
2	GTEx	Colon Sigmoid	0.2800	0.1090	2.9e-03	0.133	NA	0.031	NA	0.135	2.0e-05	NA	2.8e-02	NA	1.8e-05
3	GTEx	Muscle Skeletal	0.0391	0.0209	6.7e-03	0.028	NA	0.025	NA	0.025	8.5e-04	NA	1.4e-03	NA	1.7e-03
4	GTEx	Testis	0.2310	0.0830	2.1e-04	0.110	NA	0.037	NA	0.119	1.3e-05	NA	8.9e-03	NA	6.0e-06
5	TCGA	Breast Invasive Carcinoma	0.0128	0.0076	1.4e-03	0.008	0.005	0.000	NA	0.001	7.0e-03	2.4e-02	3.5e-01	NA	1.9e-01
6	TCGA	Cervical Squamous Cell Carcinoma	0.0560	0.0320	3.7e-03	0.023	0.038	0.024	NA	-0.005	2.6e-02	5.8e-03	2.4e-02	NA	7.0e-01
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0372	0.0204	2.3e-04	0.014	0.030	0.009	NA	0.010	9.6e-03	2.1e-04	3.1e-02	NA	2.3e-02
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1330	0.0880	5.0e-03	-0.003	0.002	0.019	NA	0.001	5.6e-01	2.5e-01	2.7e-02	NA	2.7e-01
9	TCGA	Brain Lower Grade Glioma	0.0412	0.0175	7.3e-08	0.067	0.061	0.043	NA	0.069	4.1e-08	1.8e-07	1.2e-05	NA	3.1e-08
10	TCGA	Lung Adenocarcinoma	0.0386	0.0258	8.1e-03	0.006	0.013	0.011	NA	0.010	6.5e-02	9.5e-03	1.6e-02	NA	2.2e-02
11	TCGA	Prostate Adenocarcinoma	0.0398	0.0179	3.9e-07	0.066	0.051	0.039	NA	0.047	2.1e-07	4.3e-06	6.0e-05	NA	1.0e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	2	3	4	5	6	7	8	9	10	11
HDL Cholesterol	9.8	16.4	64.8	-4.0	-2.9	-4.3	-2.4	-2.5	-3.7	-3.5	-3.8	-8.1	-4.4
Triglycerides	7.4	12.2	39.6	3.1	3.1	3.5	1.8	2.1	3.3	4.4	3.1	6.3	3.9
Medication for cholesterol, blood pressure or diabetes	6.7	11.1	16.0	-3.9	-3.0	-3.9	-4.0	-3.5	-3.2	-2.9	-3.8	-2.5	-3.9
Reaction Time	6.1	11.7	16.3	-3.7	-3.1	-3.9	-3.8	-3.7	-3.9	-2.0	-3.9	-3.3	-4.0
Qualifications: A levels/AS levels or equivalent	5.4	11.9	17.9	-3.6	-2.6	-3.8	-3.8	-3.8	-4.2	-2.7	-3.5	-3.6	-4.2
Forced vital capacity (FVC), Best measure	5.4	19.7	29.2	-5.2	-4.8	-5.4	-5.2	-4.7	-4.3	-2.8	-5.0	-2.9	-5.3
Medication for cholesterol	5.4	8.2	12.8	-3.3	-2.0	-3.3	-3.6	-3.3	-3.3	-1.5	-3.3	-2.2	-3.4
Medication: Amlodipine	5.1	7.1	10.5	2.8	3.2	2.8	3.0	2.7	2.7	2.8	3.1	1.3	3.1
Medication: Blood pressure	5.1	9.0	12.7	3.3	3.4	3.5	3.6	3.2	2.9	2.5	3.3	1.9	3.4
Maternal smoking around birth	4.9	7.1	11.5	2.9	1.2	3.0	2.9	2.6	3.0	1.9	3.2	3.1	3.4
Hypertension (Self-reported)	4.8	13.3	19.0	4.1	4.4	4.1	4.3	3.8	3.9	2.2	3.8	3.0	4.1
Cardiovascular Disease	4.6	15.2	21.4	4.6	4.2	4.3	4.6	4.0	4.0	2.9	4.1	3.6	4.4
Qualifications: College or University degree	4.5	14.2	20.5	-4.1	-3.5	-4.4	-4.1	-4.3	-4.1	-3.4	-4.2	-2.7	-4.5
Back pain experienced in last month	4.3	6.3	9.7	2.9	2.0	2.6	3.0	2.8	2.7	2.8	2.7	0.7	3.1
Breast Cancer	4.1	9.9	14.4	3.4	1.2	3.4	3.8	3.4	3.6	3.4	3.6	2.4	3.8
Blood Red Count	4.1	39.6	67.2	-6.4	-4.1	-6.9	-5.8	-6.2	-7.5	-5.4	-6.8	-8.2	-7.6
Allergy or Eczema	4.1	10.7	14.8	-3.6	-2.1	-3.8	-3.7	-3.8	-3.6	-3.3	-3.8	-2.3	-3.8
High blood pressure	4.0	11.0	15.6	3.7	3.9	3.7	3.9	3.5	3.6	2.1	3.4	2.7	3.7
Number of self-reported non-cancer illnesses	4.0	7.0	10.3	3.2	3.1	2.7	3.2	2.5	2.6	2.2	2.7	2.1	3.1
Alcohol drinker status: Never	4.0	4.8	8.9	2.6	1.8	2.8	3.0	2.2	1.8	1.6	2.7	0.9	2.6
Crohns Disease (2017)	3.8	8.4	14.3	-3.1	-1.9	-2.9	-2.8	-3.2	-3.6	-1.6	-3.3	-3.8	-3.5
Mean time to correctly identify matches	3.8	7.1	10.6	-2.9	-2.1	-3.0	-3.0	-2.8	-3.3	-1.2	-2.9	-3.1	-3.2
Vascular/heart problems diagnosed by doctor	3.7	10.1	14.9	-3.5	-3.7	-3.7	-3.9	-3.4	-3.4	-2.4	-3.3	-2.1	-3.5
Medication: Simvastatin	3.6	5.2	8.2	2.7	2.7	2.7	2.9	2.4	2.0	1.8	2.5	1.4	2.4
Medication: Cholesterol lowering	3.6	5.6	7.9	2.8	2.4	2.8	2.7	2.4	2.2	1.8	2.6	2.3	2.6
Cholesterol lowering medication	3.5	5.2	7.1	2.7	2.4	2.5	2.6	2.2	2.1	2.1	2.3	2.3	2.5
Forced expiratory volume in 1-second (FEV1), predicted	3.4	7.0	11.5	-2.7	-1.6	-3.4	-3.0	-2.9	-3.2	-1.6	-2.9	-2.3	-3.3
Pulse wave reflection index	3.3	4.1	7.4	-1.8	-2.3	-2.5	-1.9	-1.5	-2.2	-2.0	-2.1	-1.7	-2.7
Medication for hormone replacement therapy	3.1	3.5	6.2	1.8	1.1	2.3	2.5	2.3	2.4	0.6	2.2	0.7	2.3
Fluid intelligence score	3.1	6.5	10.2	-2.5	-1.4	-2.8	-2.6	-2.8	-3.1	-3.1	-2.6	-2.1	-3.2
Hayfever, allergic rhinitis or eczema	3.0	6.4	10.7	-2.8	-0.9	-2.6	-2.9	-3.2	-3.3	-2.2	-2.7	-2.3	-3.0
Forced vital capacity (FVC)	3.0	11.5	16.9	-3.9	-4.0	-4.1	-4.0	-3.5	-3.3	-2.2	-3.6	-1.9	-4.1
Health satisfaction	3.0	3.9	10.7	1.7	1.6	2.3	1.9	2.0	2.1	3.3	1.7	1.6	2.0
Overall health rating	3.0	6.4	11.4	2.8	3.4	2.8	2.8	2.5	2.3	2.6	2.6	1.9	2.8
Alzheimer’s Disease (in mother)	2.8	3.2	6.4	1.8	0.8	2.1	2.1	2.3	2.5	0.9	1.9	1.6	2.1
Other serious medical condition/disability diagnosed by doctor	2.8	3.7	7.6	2.0	2.7	2.0	2.0	1.6	1.8	2.8	1.4	1.5	2.0
Age at first live birth	2.8	5.1	7.3	-2.4	-0.8	-2.3	-2.3	-2.5	-2.7	-2.5	-2.3	-2.4	-2.6
Mineral and other dietary supplements	2.8	3.8	6.3	-2.1	-0.1	-2.5	-2.5	-2.5	-2.4	-0.6	-2.4	-1.2	-2.4
Illnesses of father: High blood pressure	2.8	3.5	6.9	2.2	2.6	2.0	2.1	2.0	1.8	1.4	1.9	1.3	1.8
Number of treatments/medications taken	2.7	4.9	7.9	2.5	1.7	2.5	2.7	2.2	2.0	2.4	2.8	1.5	2.7
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.8	13.3	-3.6	-3.1	-3.5	-3.4	-3.2	-2.8	-1.7	-3.5	-2.0	-3.6
Neuroticism (2016)	2.6	3.8	11.7	1.5	2.4	1.8	1.5	1.6	2.0	3.4	1.5	2.2	1.8
Medication: Co-codamol	2.6	3.0	4.8	1.9	1.9	1.9	2.0	1.9	1.4	2.2	2.0	1.3	1.6
Medication: Atenolol	2.6	3.3	5.8	1.9	1.7	2.4	2.0	1.8	1.8	0.8	2.3	1.2	2.4
Worrier / anxious feelings	2.6	4.9	10.3	2.3	1.3	2.1	2.3	2.6	3.2	2.1	2.1	2.3	2.5
Medication: Allopurinol	2.6	3.5	6.4	-2.2	-0.8	-1.8	-2.2	-2.5	-2.5	-0.5	-2.1	-1.5	-2.2
Prostate Cancer	2.5	3.6	5.3	-2.1	-0.8	-1.9	-2.3	-2.0	-2.1	-2.0	-2.1	-1.9	-2.1
Qualifications: None of the above	2.5	5.3	7.8	2.6	1.3	2.5	2.7	2.7	2.5	2.5	2.5	1.5	2.8
Ever had bowel cancer screening	2.5	3.0	5.1	1.6	0.6	1.9	1.5	2.0	2.3	1.6	1.7	2.2	2.0
High cholesterol (Self-reported)	2.5	4.4	6.5	2.5	1.9	2.5	2.5	2.0	1.8	2.0	2.2	1.9	2.3
Qualifications: O levels/GCSEs or equivalent	2.4	3.9	6.9	-2.0	-1.1	-2.1	-2.6	-2.4	-2.6	-1.4	-2.0	-1.2	-2.4
Ever had stillbirth, spontaneous miscarriage or termination	2.4	2.5	6.6	1.3	0.5	1.3	1.7	2.1	2.6	1.5	1.4	1.5	1.9
Eye problems/disorders: Glaucoma	2.4	2.8	6.6	2.2	2.3	1.5	1.2	1.4	1.2	0.8	1.9	2.6	1.7
Ever had prostate specific antigen (PSA) test	2.4	2.8	5.4	1.7	1.3	1.8	1.9	2.0	2.3	0.5	1.9	1.1	2.1
Crohns Disease (2012)	2.3	3.6	7.7	-2.1	-0.6	-1.8	-2.1	-2.3	-2.5	-0.5	-1.9	-2.8	-2.1
Medication: Blood pressure	2.3	4.4	7.3	2.5	1.7	2.3	2.7	2.2	2.4	1.0	2.3	1.7	2.6
Neuroticism	2.2	5.2	7.5	2.3	2.0	2.5	2.3	2.4	2.7	2.3	2.5	2.2	2.7
Ever used hormone-replacement therapy (HRT)	2.2	2.8	5.2	2.1	1.1	2.0	2.1	1.9	1.4	1.3	2.3	0.8	2.0
Medication: Ramipril	2.2	2.8	6.0	2.0	1.3	2.5	2.3	1.5	1.3	0.5	2.1	1.2	2.0
Systolic Blood Pressure	2.1	10.3	16.9	3.6	3.5	3.6	4.1	3.6	3.6	1.7	3.4	2.1	3.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.9	3.9	2.0	1.6	1.9	1.8	1.7	1.6	1.7	2.0	1.6	1.9
Financial difficulties in last 2 years	2.1	2.8	9.7	1.2	0.9	1.2	1.2	2.0	2.2	3.1	1.3	2.0	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	5.5	2.0	0.8	1.5	1.7	2.1	2.3	2.0	2.0	1.9	1.9
Knee pain experienced in last month	2.1	3.2	11.2	1.6	1.8	1.7	2.1	1.7	1.7	3.3	1.6	0.2	1.7
Mood swings	2.1	3.7	6.0	1.7	2.5	1.9	1.7	1.9	2.2	2.3	2.1	1.4	2.2
Deep venous thrombosis (DVT) (self-reported)	2.1	2.8	4.3	-2.0	-1.1	-1.5	-1.7	-1.9	-1.7	-1.4	-2.1	-1.9	-1.9
Heel T-Score	2.0	16.1	28.8	4.3	3.2	4.6	4.2	3.6	4.7	3.1	4.2	4.3	5.4
Average weekly fortified wine intake	2.0	2.3	4.0	1.8	0.9	1.6	1.8	2.0	1.9	1.1	1.6	1.2	1.7
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.2	6.1	1.7	2.4	1.8	1.4	1.6	1.6	2.0	1.8	2.5	1.6
Alzheimer’s Disease (including proxy)	1.9	2.7	6.0	1.5	0.5	1.8	1.8	2.0	2.4	1.4	1.5	1.8	1.9
Heart attack	1.9	2.4	4.4	1.9	1.3	1.7	2.1	1.7	1.4	1.6	1.8	0.7	1.7
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	4.2	-1.8	-1.9	-1.2	-1.2	-1.8	-1.7	-2.0	-1.6	-1.5	-1.7
Pulse wave Arterial Stiffness index	1.9	2.2	4.4	-1.4	-0.4	-1.8	-1.6	-1.2	-2.1	-0.3	-1.6	-2.0	-2.1
Neck or shoulder pain in last month	1.9	2.8	4.6	1.8	2.1	1.6	1.5	1.5	1.7	2.2	1.8	1.2	1.9
Supplements: Zinc	1.8	1.9	3.0	1.7	1.6	1.3	1.1	1.4	1.5	-0.1	1.6	1.7	1.7
Allergy	1.8	4.0	6.2	2.1	1.2	2.0	2.3	2.4	2.5	2.3	2.0	1.5	2.3
Long-standing illness, disability or infirmity	1.8	2.8	8.4	1.7	2.1	1.8	1.7	1.4	1.2	2.9	1.6	0.3	1.7
Sensitivity / hurt feelings	1.7	2.9	4.0	1.8	1.7	1.7	1.6	1.5	2.0	2.0	1.8	1.8	1.9
Age when periods started (menarche)	1.7	4.1	9.1	-2.3	-1.6	-1.9	-2.0	-2.2	-2.4	-0.7	-2.1	-3.0	-2.2
Neuroticism score	1.7	3.5	5.8	1.8	1.8	2.0	1.4	1.6	2.1	2.3	1.8	2.4	2.1
Blood clot in the leg (DVT)	1.7	2.2	4.0	-1.7	-0.9	-1.2	-1.3	-1.8	-1.6	-1.2	-1.8	-2.0	-1.5
Number of children fathered	1.7	1.9	3.4	1.5	1.5	1.6	1.4	1.2	1.5	1.0	1.5	1.3	1.8
Verbal and Numeric Reasoning (VNR)	1.6	3.8	7.5	-1.9	-1.1	-2.3	-2.2	-2.1	-2.6	-1.9	-2.0	-1.0	-2.7
Standing height	1.6	16.2	24.9	-4.9	-3.8	-5.0	-4.9	-4.4	-3.9	-1.1	-4.8	-3.1	-4.8
Supplements: Vitamin C	1.6	1.9	5.2	-1.4	-1.0	-1.6	-1.6	-1.3	-0.9	-2.3	-1.6	-0.5	-1.4
Medication: Gliclazide	1.6	1.8	3.2	1.4	-0.3	1.3	1.4	1.5	1.5	1.3	1.4	1.8	1.5
Heart disease (siblings)	1.6	2.0	2.9	1.5	1.6	1.6	1.4	1.6	1.5	0.7	1.7	1.3	1.5
Alzheimer’s Disease (in father)	1.5	1.7	2.5	1.6	1.4	1.4	1.2	1.3	1.1	1.4	1.2	1.6	1.3
Body Mass Index (BMI) (2010)	1.5	2.1	4.1	-1.4	-0.8	-1.6	-1.7	-1.6	-2.0	-0.8	-1.4	-1.8	-1.8
Blood White Count	1.5	10.8	15.1	3.7	3.3	3.9	3.9	3.3	2.9	3.3	3.6	2.5	3.7
Noisy workplace	1.5	1.8	5.3	1.4	0.4	1.3	2.3	1.6	1.9	0.2	1.4	0.2	1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	5.1	1.7	1.0	1.2	1.1	1.4	1.0	1.0	1.3	2.3	1.1
Family relationship satisfaction	1.5	1.8	3.6	1.3	1.6	1.4	0.9	1.3	1.4	1.9	1.1	1.4	1.3
Neuroticism (Nagel 2018)	1.4	3.4	4.2	2.0	1.9	1.9	1.8	1.9	2.1	2.0	2.0	1.9	2.0
Stomach or abdominal pain in last month	1.4	1.8	7.3	1.1	1.3	1.1	1.2	1.1	1.1	2.7	1.2	0.7	1.4
Forced expiratory volume in 1-second (FEV1)	1.4	4.9	7.5	-2.7	-2.6	-2.6	-2.5	-2.4	-2.0	-1.2	-2.6	-1.1	-2.7
Glaucoma (self-reported)	1.4	1.7	4.0	1.8	1.7	1.3	1.0	1.1	0.7	0.6	1.5	2.0	1.2
Medication: Bendroflumethiazide	1.4	2.2	3.6	1.9	1.9	1.6	1.6	1.6	1.3	0.9	1.5	1.5	1.5
Ever depressed for a whole week	1.4	1.7	4.8	1.0	-0.2	0.7	1.0	1.3	2.2	1.8	0.7	2.1	1.2
Heart attack/myocardial infarction (self-reported)	1.4	1.9	3.4	1.6	1.4	1.5	1.8	1.4	1.2	1.5	1.5	0.4	1.5
Depressed Affect (Nagel 2018)	1.3	2.8	4.6	1.5	2.1	1.8	1.5	1.6	1.7	2.1	1.9	0.7	2.0
Lung FEV1/FVC ratio	1.3	6.5	10.1	3.0	2.8	3.1	3.2	2.6	2.6	1.4	2.3	2.5	2.8
Lung FVC	1.3	6.7	11.4	-3.0	-3.4	-2.8	-2.8	-2.7	-2.6	-2.5	-2.4	-1.4	-2.9
Ever had hysterectomy (womb removed)	1.3	1.4	3.9	1.2	0.9	0.9	1.2	1.0	1.3	2.0	1.1	1.2	1.3
Number of live births	1.3	1.8	4.6	1.3	2.2	1.0	1.0	1.4	1.5	1.8	1.0	1.5	1.2
Tense / ‘highly strung’	1.3	2.1	3.9	1.7	2.0	1.6	1.4	1.4	1.0	1.2	1.5	1.6	1.4
Leg pain on walking	1.3	1.6	4.3	1.0	0.7	1.1	1.2	1.4	2.1	1.4	0.9	1.5	1.5
Loneliness, isolation	1.3	1.8	4.9	1.3	2.2	1.4	1.0	1.4	1.1	1.6	1.3	1.0	1.2
Supplements: Fish oil (including cod liver oil)	1.3	1.6	3.5	1.1	-0.6	1.7	1.9	1.5	1.5	-0.2	1.7	-0.1	1.7
Unable to work because of sickness or disability	1.3	1.6	4.5	1.5	2.1	1.2	1.6	1.4	0.6	1.1	1.5	-0.4	1.2
Major Depression (MDD)	1.2	1.5	6.3	0.9	0.4	1.1	0.9	1.1	1.3	2.5	1.2	1.2	1.2
Height	1.2	22.9	35.8	-5.7	-3.5	-6.0	-5.9	-5.4	-5.1	-1.5	-5.6	-4.3	-5.6
Hearing difficulty/problems: Yes	1.2	1.9	5.4	-0.7	-0.1	-1.2	-1.0	-1.4	-2.3	-2.0	-1.2	-1.5	-1.8
Worry too long after embarrassment	1.2	2.1	4.5	-1.5	-0.9	-1.5	-2.1	-2.1	-1.4	0.3	-1.8	0.8	-1.6
Pulse wave peak to peak time	1.2	1.4	2.9	1.0	0.1	1.5	1.3	0.9	1.7	0.2	1.2	1.7	1.7
Chest pain or discomfort	1.2	1.7	5.2	1.2	0.8	1.6	1.4	1.2	1.0	2.3	1.4	0.5	1.5
Age at last live birth	1.2	1.7	2.9	-1.5	0.6	-1.5	-1.6	-1.5	-1.4	-1.1	-1.6	-0.8	-1.7
Qualifications: nursing, teaching	1.2	1.9	3.0	-1.2	-0.3	-1.6	-1.5	-1.6	-1.7	-1.6	-1.4	-1.1	-1.7
Average weekly champagne plus white wine intake	1.2	1.6	4.5	-1.2	-1.8	-1.3	-1.2	-0.9	-0.9	-2.1	-1.4	-0.2	-1.6
Tinnitus: Yes, now most or all of the time	1.2	1.5	3.9	-1.6	-0.9	-0.8	-1.3	-1.2	-0.9	-2.0	-1.2	-1.1	-1.2
Irritability	1.2	2.0	3.4	1.7	1.8	1.6	1.3	1.5	0.7	1.8	1.7	1.4	1.2
Alcohol drinker status: Previous	1.2	1.3	2.9	-1.6	-1.7	-1.4	-1.2	-1.0	-0.2	-0.8	-1.3	-1.1	-0.9
Worry (Nagel 2018)	1.1	2.2	3.6	1.7	1.1	1.6	1.9	1.6	1.9	1.1	1.6	1.1	1.8
Mean Putamen Volume	1.1	1.3	5.0	1.4	0.8	0.8	1.0	1.1	1.0	2.2	0.7	1.0	1.0
Average weekly spirits intake	1.1	1.3	2.7	1.5	0.8	1.4	1.6	1.4	0.8	0.8	1.5	-0.4	1.3
Number of incorrect matches in round	1.1	1.7	3.4	1.3	0.2	1.4	1.4	1.4	1.8	1.1	1.4	1.2	1.9
Gout (self-reported)	1.1	1.5	2.6	-1.6	-1.0	-1.4	-1.3	-1.2	-1.3	-0.4	-1.5	-1.1	-1.6
Heart disease (mother)	1.1	1.3	2.6	-1.1	-1.0	-1.4	-1.2	-1.1	-1.1	-1.6	-1.1	-1.3	-1.2
Medication: Aspirin	1.1	1.5	3.9	1.1	2.0	1.2	1.2	1.3	1.3	1.4	1.2	0.2	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	4.2	-1.2	-0.8	-1.8	-1.9	-1.6	-2.0	-1.8	-1.5	-0.3	-2.0
Basal cell carcinoma (self-reported)	1.1	1.3	3.6	1.1	0.7	1.1	1.0	1.1	1.4	1.4	0.9	1.9	1.1
Angina	1.0	1.3	2.2	1.2	0.6	1.2	1.5	1.5	1.4	1.4	1.2	0.2	1.2
High blood pressure (mother)	1.0	1.4	3.4	-1.5	-1.4	-1.5	-0.9	-1.0	-0.4	-0.2	-1.9	-1.3	-1.2
Exposure to tobacco smoke at home	1.0	1.2	3.2	1.3	1.8	1.2	1.0	1.1	0.7	1.0	1.2	0.4	1.1
Birth weight	1.0	2.1	3.3	-1.7	-1.6	-1.7	-1.8	-1.8	-1.4	-1.2	-1.5	0.1	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.3	0.8	1.0	1.5	1.4	1.1	1.0	1.0	1.2	-0.4	1.4
Breast cancer (self-reported)	1.0	1.1	5.0	0.5	0.8	0.7	0.6	0.9	1.7	1.0	0.5	2.2	0.9
Medication: Aspirin	1.0	1.3	4.2	1.0	2.1	1.0	1.2	1.1	1.0	1.6	0.9	0.1	1.0
Pain experienced in last month	1.0	1.6	5.1	-1.3	-1.1	-1.3	-1.3	-1.0	-1.2	-2.2	-1.3	0.1	-1.6
Irritable Bowel Disease (IBD)	0.9	2.2	3.8	-1.5	-0.5	-1.7	-1.6	-1.6	-1.9	-0.3	-1.7	-1.8	-1.9
Relative age of first facial hair	0.9	1.9	3.1	-1.6	-1.6	-1.5	-1.8	-1.1	-1.2	-1.5	-1.5	-0.7	-1.7
Fed-up feelings	0.9	1.7	3.5	1.3	1.3	1.5	1.4	1.0	1.1	1.9	1.5	0.5	1.6
Taking other prescription medications	0.9	1.5	3.4	1.4	0.4	1.3	1.8	1.2	1.3	1.2	1.4	0.3	1.5
Leg fat-free mass (right)	0.9	4.8	9.8	-2.2	-1.3	-3.1	-2.6	-2.3	-2.4	0.3	-2.7	-1.7	-2.9
Osteoarthritis (self-reported)	0.9	1.1	3.3	1.3	0.8	0.9	1.1	0.8	0.7	1.8	0.9	1.3	1.1
Leg predicted mass (right)	0.9	4.9	9.8	-2.2	-1.3	-3.1	-2.7	-2.4	-2.4	0.3	-2.8	-1.7	-2.9
Guilty feelings	0.9	1.3	9.3	0.6	0.9	0.7	0.0	0.6	1.1	1.2	0.4	3.1	0.5
Number of operations (self-reported)	0.9	1.3	2.6	1.4	1.0	1.2	0.8	0.7	0.5	1.3	1.6	1.6	1.4
Intelligence (Savage-Jansen 2018)	0.8	2.5	5.3	-1.1	-1.1	-2.1	-1.9	-1.5	-2.2	-1.1	-1.7	0.2	-2.3
Bipolar Disorder (2011)	0.8	0.8	2.9	1.2	-0.5	0.4	0.9	1.7	0.9	0.9	1.1	0.2	0.5
Leg fat-free mass (left)	0.8	4.1	8.0	-2.0	-1.1	-2.8	-2.4	-2.1	-2.2	0.7	-2.5	-1.7	-2.6
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	3.8	0.8	1.0	0.6	0.3	0.4	0.6	2.0	0.8	1.4	0.9
Time employed in main current job	0.8	0.9	1.9	1.0	0.6	1.0	1.4	1.1	1.2	0.7	1.0	0.2	1.3
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.5	1.1	1.1	0.9	1.0	1.0	1.0	1.0	0.9	1.6	1.0
Number of full brothers	0.8	1.1	2.1	1.1	1.0	1.0	0.8	1.0	0.9	1.5	0.9	1.4	1.0
Angina (self-reported)	0.8	1.1	1.9	1.1	0.5	1.0	1.4	1.3	1.3	1.4	1.1	0.1	1.1
Comparative height size at age 10	0.8	4.6	7.1	-2.4	-1.8	-2.7	-2.5	-2.3	-2.4	-1.2	-2.3	-1.8	-2.6
Miserableness	0.8	1.4	5.5	1.1	1.5	0.9	0.6	1.0	1.0	2.3	0.9	1.3	1.1
Arm fat-free mass (left)	0.8	3.9	7.3	-1.9	-0.7	-2.7	-2.3	-2.2	-2.3	0.7	-2.5	-1.4	-2.7
Average weekly beer plus cider intake	0.8	1.1	3.0	-0.7	1.4	-0.7	-0.9	-1.2	-1.7	0.5	-1.0	-1.3	-1.2
Blood Platelet Count	0.7	8.2	18.5	3.3	1.5	3.4	4.3	4.1	3.1	0.6	3.4	0.7	3.0
BMI	0.7	3.8	9.1	-1.4	-0.6	-2.2	-1.8	-2.0	-3.0	-1.0	-2.0	-2.8	-2.5
Waist Hip Ratio (WHR)	0.7	3.2	5.3	1.6	1.1	2.3	1.9	1.9	1.8	2.1	1.8	2.2	1.8
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.9	-0.8	-0.1	-1.2	-0.9	-0.8	-0.8	1.1	-0.8	-1.4	-0.8
Medication: Levothyroxine sodium	0.7	1.1	3.3	1.1	1.3	1.1	1.2	0.9	0.6	1.8	1.3	0.0	1.0
Sitting height	0.7	5.2	9.1	-2.6	-3.0	-2.8	-2.4	-2.5	-2.1	-0.7	-2.6	-1.4	-2.6
Leg predicted mass (left)	0.7	3.9	7.5	-2.0	-1.1	-2.7	-2.3	-2.1	-2.2	0.7	-2.5	-1.6	-2.6
Alcohol usually taken with meals	0.7	1.1	3.2	0.7	-0.7	0.8	1.1	1.0	1.8	-0.5	0.9	1.4	1.4
Nervous feelings	0.7	1.2	1.9	1.3	0.8	1.2	1.4	1.1	1.3	-0.2	1.3	1.3	1.2
Pulse rate	0.7	1.2	3.2	-1.0	1.3	-0.5	-1.3	-1.2	-1.3	1.8	-1.1	-0.2	-1.0
Prospective memory result	0.7	0.8	1.9	0.7	-0.8	0.5	1.0	1.1	1.4	1.1	0.9	-0.1	1.1
Illnesses of mother	0.7	0.8	4.6	1.0	2.1	0.9	0.4	0.4	-0.3	0.7	1.0	0.5	0.6
Whole body fat-free mass	0.7	3.9	7.9	-2.0	-1.0	-2.8	-2.4	-2.1	-2.0	0.7	-2.6	-1.3	-2.6
Handedness (chirality/laterality): Left-handed	0.7	0.9	1.6	1.2	1.0	0.9	1.3	1.2	0.9	0.3	1.1	-0.1	1.1
Whole body water mass	0.7	4.0	8.0	-2.0	-1.0	-2.8	-2.4	-2.1	-2.1	0.6	-2.6	-1.3	-2.7
Basal metabolic rate	0.7	3.8	7.6	-1.9	-0.9	-2.8	-2.3	-2.1	-2.2	0.7	-2.5	-1.5	-2.6
Arm predicted mass (left)	0.7	3.6	7.0	-1.8	-0.5	-2.6	-2.3	-2.1	-2.2	0.6	-2.5	-1.3	-2.6
Trunk fat mass	0.6	2.6	5.9	-1.2	-0.3	-1.9	-1.5	-1.6	-2.4	0.2	-1.7	-2.3	-1.9
Hearing difficulty/problems with background noise	0.6	0.9	2.6	-0.4	0.2	-1.1	-0.6	-0.9	-1.4	-1.6	-0.9	-0.8	-1.1
Illnesses of siblings	0.6	0.8	1.8	-1.0	-1.4	-1.0	-1.0	-1.0	-0.8	-0.9	-0.9	-0.3	-0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.1	0.7	0.9	1.3	1.4	0.9	0.8	0.3	0.9	-0.4	0.9
Arm predicted mass (right)	0.6	3.2	6.0	-1.7	-0.3	-2.4	-2.2	-1.9	-2.0	0.9	-2.4	-1.1	-2.4
Pulse rate, automated reading	0.6	2.0	5.1	1.0	2.2	1.4	0.5	1.0	0.7	2.2	1.1	2.2	1.0
Mother’s age at death	0.6	0.8	1.5	-1.0	-1.1	-0.8	-0.9	-0.9	-0.7	-1.2	-0.8	-1.0	-0.7
Medication: Lisinopril	0.6	0.8	3.1	0.8	0.4	0.5	1.1	1.2	1.1	1.8	0.5	0.4	0.6
Coronary Artery Disease (CAD)	0.5	0.6	1.5	0.2	0.8	0.7	0.9	1.2	0.9	1.1	0.9	-0.6	0.6
Severe depression (siblings)	0.5	0.5	2.7	0.1	0.8	0.1	0.3	0.8	0.9	1.6	0.3	-0.9	0.3
Trunk fat percentage	0.5	2.0	5.8	-0.9	-0.1	-1.5	-1.2	-1.4	-2.4	-0.1	-1.3	-2.4	-1.6
Supplements: Glucosamine	0.5	0.6	1.3	0.7	0.1	1.0	0.9	1.1	1.0	-0.3	1.0	0.1	0.8
Pain all over the body in last month	0.5	0.6	2.6	0.9	-0.6	0.3	0.8	0.4	0.5	1.6	0.5	0.6	0.8
Trunk fat-free mass	0.5	3.1	6.5	-1.8	-0.9	-2.5	-2.1	-1.8	-1.6	0.8	-2.4	-0.9	-2.4
Lung cancer (father)	0.5	0.6	2.0	0.8	0.6	1.4	0.9	0.5	0.3	0.4	1.1	0.1	0.9
Trunk predicted mass	0.5	2.8	5.9	-1.7	-0.8	-2.4	-2.0	-1.7	-1.6	0.8	-2.2	-0.8	-2.3
Breastfed as a baby	0.5	0.7	1.2	-1.0	-1.1	-0.8	-0.6	-0.9	-0.7	-0.2	-1.1	-0.9	-0.9
Ever highly irritable/argumentative for 2 days	0.5	0.7	2.7	0.2	-0.7	0.4	0.2	0.5	1.2	1.6	0.2	1.3	0.6
Headache pain in last month	0.5	0.8	1.5	0.9	1.2	1.0	1.0	0.9	0.9	0.7	1.1	0.0	1.1
Arm fat-free mass (right)	0.5	2.4	4.6	-1.5	-0.4	-2.1	-1.8	-1.6	-1.6	1.2	-2.0	-1.0	-2.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.8	0.3	1.7	0.7	0.3	0.5	0.7	0.7	0.4	1.0	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	1.8	-0.9	-1.4	-1.2	-1.0	-0.6	-0.5	-1.1	-1.0	0.0	-1.1
Alcohol intake frequency.	0.5	1.1	2.7	0.3	-0.3	0.9	1.2	1.1	1.4	1.6	1.0	-1.1	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	1.0	1.1	1.0	1.0	0.8	0.4	-0.0	0.9	-0.1	0.9
Illnesses of father: Heart disease	0.5	0.7	1.7	0.7	1.3	0.6	1.2	1.2	0.9	0.0	0.7	-0.5	0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.6	5.2	0.5	-0.4	0.3	0.2	0.1	0.6	-0.3	0.2	2.3	0.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.8	0.6	1.1	0.8	0.7	0.5	0.5	1.7	0.3	0.1	0.7
HbA1C	0.4	0.4	2.0	-0.8	0.6	0.2	0.4	-0.5	-0.5	-1.1	-0.2	-1.4	-0.2
Lupus	0.4	0.6	4.9	-0.7	0.0	0.2	0.5	0.1	0.5	0.8	-0.0	-2.2	0.2
Vitamin and mineral supplements	0.4	0.5	2.7	0.5	1.2	0.4	0.3	-0.2	-0.7	1.6	0.4	-0.1	0.1
Diabetes (father)	0.4	0.5	4.4	0.5	-0.1	0.1	0.7	0.1	-0.3	-2.1	-0.0	0.3	-0.1
Diabetes (mother)	0.4	0.5	1.6	0.9	-1.0	0.6	1.3	0.7	0.5	-0.8	0.3	0.7	0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.1	-0.9	-0.5	-0.7	-0.8	-0.9	-0.6	-0.9	-1.1	-0.4	-0.7
Mouth/teeth dental problems	0.4	0.6	3.8	-0.7	-1.9	-0.7	-0.5	-0.6	-0.3	-0.5	-0.6	-0.6	-0.6
Weight	0.4	2.1	3.9	-1.1	-0.2	-1.9	-1.4	-1.4	-2.0	1.0	-1.6	-1.7	-1.8
Impedance of arm (right)	0.4	2.1	5.4	-1.6	-2.3	-1.1	-1.3	-1.3	-1.1	-2.2	-1.0	-1.4	-1.0
Mouth/teeth dental problems: Dentures	0.4	0.7	6.6	0.7	2.6	0.2	-0.0	0.0	-0.5	0.5	0.3	0.5	0.1
Medication: Paracetamol	0.4	0.7	1.9	1.0	0.2	1.4	1.0	0.4	0.3	1.1	1.2	0.5	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.3	0.7	-0.1	0.5	0.7	0.8	1.2	-0.2	0.6	1.0	0.6
Shortness of breath walking on level ground	0.4	0.4	1.6	0.8	1.3	0.4	0.1	0.6	0.1	0.6	0.4	1.3	0.2
Medication: Ibuprofen	0.4	0.5	2.5	-0.6	-0.5	-0.7	-0.6	-0.5	-0.5	-1.6	-0.6	-0.2	-0.6
Whole body fat mass	0.4	1.5	4.0	-0.7	0.1	-1.4	-1.0	-1.2	-2.0	0.4	-1.2	-1.9	-1.5
Smoking status: Current	0.4	0.6	1.4	1.0	1.0	0.5	0.4	0.6	0.3	0.7	1.1	1.2	0.6
Wears glasses or contact lenses	0.4	0.5	3.9	-0.1	-0.5	-0.5	-0.3	-0.3	-0.5	2.0	-0.1	-0.6	-0.2
Hearing aid user	0.4	0.5	1.7	0.7	1.3	0.8	0.8	0.9	0.3	0.1	0.7	-0.1	0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.8	-1.0	-1.3	-0.6	-0.9	-0.5	-0.4	-0.2	-0.7	-0.8	-0.5
Supplements: Calcium	0.4	0.4	0.8	0.7	0.4	0.7	0.8	0.9	0.8	-0.5	0.5	0.6	0.6
Bipolar Disorder (2018)	0.3	0.5	1.3	0.7	0.1	0.5	0.3	0.9	1.1	0.7	0.8	1.1	0.8
Bipolar Disorder or Schizophrenia	0.3	0.8	2.6	0.6	0.3	0.7	0.9	1.2	1.6	0.7	0.9	0.8	1.1
Schizophrenia (2018)	0.3	0.5	2.0	0.3	0.4	0.4	0.9	1.1	1.4	0.2	0.5	0.8	0.7
Schizophrenia (2014)	0.3	0.7	1.6	0.7	0.7	0.9	1.0	1.2	1.3	0.1	0.8	0.6	1.0
Blood Eosinophil Count	0.3	2.3	5.7	1.5	0.6	1.1	1.4	2.0	2.4	1.5	1.1	1.6	1.8
Smoking Status	0.3	0.6	2.1	0.8	1.1	0.4	0.4	0.8	0.7	0.5	0.9	1.5	0.7
Respiratory disease	0.3	0.8	1.8	-0.7	-0.4	-0.8	-0.9	-0.8	-1.3	-0.9	-0.7	-1.2	-1.1
Tanning	0.3	3.4	5.7	2.2	1.3	1.8	2.4	2.2	2.3	-0.5	2.1	1.5	2.1
Hand grip strength (left)	0.3	0.9	2.1	-1.2	-0.6	-1.4	-1.1	-1.0	-0.5	-0.7	-1.3	-0.5	-1.1
Systolic blood pressure, automated reading	0.3	0.8	3.7	0.9	1.9	0.7	1.1	0.9	0.8	-0.1	0.6	0.1	0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.2	0.6	1.1	0.2	0.3	0.3	0.2	1.0	0.2	0.3	0.4
Current tobacco smoking	0.3	0.6	1.9	0.9	1.3	0.4	0.3	0.4	0.2	0.3	0.9	1.4	0.5
Had other major operations	0.3	0.3	1.5	0.5	1.2	0.2	-0.0	0.2	0.0	0.9	0.2	0.8	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.6	1.0	0.3	1.1	1.3	0.7	0.9	0.6	1.1	0.4	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	1.9	0.8	1.4	0.6	0.6	0.6	0.5	1.1	0.5	0.3	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	2.3	-0.0	-0.3	-0.4	0.1	0.1	0.7	1.5	-0.4	0.0	0.2
Loud music exposure frequency	0.3	0.3	1.5	-0.5	-0.0	-0.0	0.0	-0.4	-0.4	-1.2	-0.2	-1.2	-0.4
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.3	0.6	-0.2	1.1	1.0	0.4	0.4	0.2	1.0	0.4	0.7
Comparative body size at age 10	0.3	0.9	3.4	1.0	0.2	0.6	0.3	0.9	0.9	1.3	0.8	1.8	0.9
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	3.8	0.1	-0.0	0.3	-0.1	-0.4	-0.5	-1.9	0.4	0.0	0.2
Illnesses of siblings: Diabetes	0.3	0.4	0.9	-0.6	0.3	-0.5	-0.6	-0.7	-0.9	-0.0	-0.8	-0.7	-0.6
Commuting to job workplace: Walk	0.3	0.3	2.5	-0.4	-1.6	-0.5	-0.5	-0.4	-0.1	-0.3	-0.1	0.3	-0.3
Arm fat mass (left)	0.3	1.1	3.4	-0.4	0.1	-1.3	-0.9	-1.0	-1.8	0.5	-1.0	-1.4	-1.4
Age started oral contraceptive pill	0.3	0.3	1.5	0.5	1.2	0.3	0.4	0.6	0.7	-0.6	0.3	0.1	0.5
Myopia	0.3	0.4	2.2	0.1	-1.1	0.6	0.3	0.1	0.7	0.3	0.3	1.5	0.5
Depression (Nagel 2018)	0.2	0.3	1.9	0.3	1.0	0.5	0.2	0.0	0.1	1.4	0.4	0.1	0.4
Ovarian Cancer	0.2	0.2	0.5	0.5	0.1	0.6	0.7	0.5	0.3	0.5	0.6	-0.0	0.6
Age at First Birth	0.2	0.2	0.7	0.5	-0.5	0.4	0.6	0.2	0.3	0.9	0.3	0.8	0.4
Primary Biliary Cirrhosis	0.2	0.2	0.8	-0.0	-0.8	0.2	0.0	0.3	0.5	0.9	-0.1	0.8	0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.0	1.0	-0.0	0.6	0.9	0.7	-0.0	-0.1	0.8	-0.1	0.4
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.1	-0.2	1.0	0.3	-0.1	-0.0	0.3	1.1	-0.1	-0.0	0.0
Medication: Metformin	0.2	0.2	0.8	0.7	0.3	0.2	0.5	0.9	0.2	0.7	0.3	0.1	0.1
Pack years adult smoking proportion	0.2	0.2	0.6	-0.5	0.5	-0.3	0.1	-0.7	-0.1	-0.7	-0.6	-0.8	0.1
Townsend deprivation index at recruitment	0.2	0.2	0.6	0.4	0.2	0.7	0.4	0.8	0.8	0.4	0.3	0.5	0.4
Serious illness, injury or assault to yourself	0.2	0.2	0.7	-0.4	-0.3	-0.6	-0.3	-0.3	-0.3	0.4	-0.9	-0.3	-0.7
Multivitamins +/- minerals	0.2	0.2	1.0	0.1	-0.5	0.3	0.2	0.7	1.0	-0.2	0.4	0.4	0.6
Chronic bronchitis/emphysema (father)	0.2	0.2	1.1	-0.3	-1.1	-0.2	-0.3	-0.5	-0.5	-0.4	-0.1	-0.3	-0.2
Diabetes (self-reported)	0.2	0.4	1.1	1.0	0.5	0.7	1.0	0.8	0.1	0.3	0.7	-0.3	0.5
Hip circumference	0.2	1.0	2.3	-0.6	0.2	-1.4	-1.1	-1.1	-1.5	0.7	-1.1	-1.0	-1.2
Father’s age at death	0.2	0.2	0.8	-0.6	0.1	-0.4	-0.8	-0.7	0.2	-0.0	-0.9	0.4	0.1
Hair/balding pattern: Pattern 3	0.2	0.3	1.2	0.1	0.6	0.7	0.8	0.4	1.1	0.5	0.1	0.1	0.6
Happiness	0.2	0.2	0.7	-0.5	-0.1	-0.4	-0.6	-0.1	0.1	0.8	-0.6	0.1	-0.4
Medication: Lansoprazole	0.2	0.3	0.6	0.5	0.1	0.5	0.8	0.5	0.6	0.8	0.4	-0.3	0.5
Impedance of arm (left)	0.2	1.0	2.9	-1.2	-1.7	-0.5	-0.9	-0.7	-0.7	-1.7	-0.4	-1.1	-0.6
Arm fat mass (right)	0.2	0.8	2.5	-0.3	0.0	-1.3	-0.8	-0.8	-1.6	0.3	-0.9	-1.2	-1.2
Body fat percentage	0.2	0.8	3.5	-0.2	0.4	-0.8	-0.5	-0.7	-1.7	0.2	-0.6	-1.9	-0.9
Leg fat percentage (right)	0.2	0.9	1.9	1.3	1.4	0.9	1.2	0.8	-0.0	1.0	0.9	-0.7	0.8
Exposure to tobacco smoke outside home	0.2	0.3	1.1	0.5	0.3	0.3	0.6	0.6	-0.1	-0.6	0.3	-1.1	0.2
Wheeze or whistling in the chest in last year	0.2	0.4	0.7	-0.5	0.1	-0.8	-0.7	-0.3	-0.7	0.8	-0.6	-0.6	-0.8
Eye problems/disorders: None of the above	0.2	0.3	1.9	-0.5	-1.4	-0.4	0.0	-0.0	0.2	-0.4	-0.5	-0.2	-0.5
Migraine (self-reported)	0.2	0.2	0.5	0.3	0.7	0.5	0.3	0.4	0.1	0.7	0.5	-0.6	0.2
Had major operations	0.2	0.3	0.6	0.7	0.8	0.5	0.4	0.6	0.2	-0.1	0.6	-0.3	0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.4	0.7	1.2	0.3	0.3	0.2	0.1	0.4	0.4	0.4	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.7	0.3	0.4	0.0	0.4	0.1	0.1	1.3	-0.1	-0.4	0.2
Smoking status: Previous	0.2	0.3	0.8	-0.7	0.2	-0.6	-0.7	-0.6	-0.2	-0.9	-0.8	-0.2	-0.5
Friendships satisfaction	0.2	0.2	0.7	0.3	0.2	0.4	0.3	0.3	0.7	-0.3	0.3	0.9	0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.7	0.8	0.5	0.3	0.4	0.7	0.4	0.4	0.7	0.6	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.6	0.7	-0.3	0.5	0.5	0.4	0.4	-0.2	0.5	0.8	0.6
Osteoporosis (self-reported)	0.2	0.2	1.5	-0.4	-1.2	-0.2	-0.4	-0.1	-0.1	0.1	-0.2	-0.4	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	0.6	-0.3	-0.7	-0.2	-0.7	-0.4	-0.2	0.5	-0.3	0.8	-0.2
Ever taken oral contraceptive pill	0.2	0.2	0.7	-0.4	-0.3	-0.8	-0.4	0.1	-0.0	-0.4	-0.5	0.1	-0.8
Financial situation satisfaction	0.2	0.2	1.3	0.1	1.1	0.4	0.2	0.1	0.6	0.6	-0.1	0.5	0.3
Leg fat percentage (left)	0.2	0.9	2.0	1.4	1.4	0.8	1.2	0.9	0.1	0.8	0.9	-0.5	0.8
Risk taking	0.2	0.3	1.6	-0.4	0.1	-0.3	-0.8	-0.4	-0.5	-1.2	-0.7	-0.2	-0.6
Schizophrenia vs Biploar Disorder	0.1	0.1	0.8	-0.4	-0.1	0.3	0.1	-0.3	0.2	0.3	0.0	-0.9	0.3
Ulcerative Colitis (UC)	0.1	0.2	1.2	0.3	1.1	-0.2	-0.3	-0.0	-0.3	0.9	0.0	0.2	-0.1
LDL Cholesterol	0.1	0.2	0.8	-0.3	-0.4	0.2	-0.4	-0.6	-0.3	-0.1	-0.2	0.9	-0.2
Rheumatoid Arthritis	0.1	0.1	0.7	0.1	0.8	0.3	0.1	-0.0	-0.1	0.2	0.0	0.0	0.3
Ulcerative Colitis	0.1	0.1	0.6	0.3	0.7	-0.4	-0.2	0.2	-0.0	0.5	-0.1	-0.1	-0.1
Hypothyroidism (self reported)	0.1	0.2	0.6	0.4	0.8	0.2	0.3	-0.0	-0.5	0.0	0.5	-0.7	0.1
Chronotype (morning person)	0.1	0.3	0.7	-0.8	-0.3	-0.2	-0.5	-0.8	-0.2	-0.7	-0.6	-0.5	-0.1
Hair Pigment	0.1	1.5	4.7	0.5	2.2	1.7	0.9	0.7	1.1	1.8	1.0	0.4	1.2
Impedance of leg (right)	0.1	0.2	0.9	0.0	0.2	0.9	0.5	0.0	-0.1	-1.0	0.5	-0.4	0.5
Hand grip strength (right)	0.1	0.4	1.0	-0.7	-0.2	-1.0	-0.6	-0.5	-0.3	0.4	-0.8	-0.9	-0.7
Relative age voice broke	0.1	0.1	0.5	-0.3	-0.5	0.2	-0.0	-0.3	-0.2	-0.7	-0.1	-0.4	0.0
Body mass index (BMI)	0.1	0.6	2.0	1.1	1.4	0.2	0.7	0.5	-0.4	1.4	0.4	-0.4	0.2
Impedance of leg (left)	0.1	0.4	3.2	-0.3	-0.1	0.3	0.0	-0.3	-0.5	-1.8	0.1	-0.6	0.0
Waist circumference	0.1	0.3	1.4	0.2	0.7	-0.2	0.1	-0.1	-0.7	1.2	-0.2	-0.4	-0.3
Past tobacco smoking	0.1	0.1	0.4	0.5	-0.3	0.2	0.6	0.3	0.0	0.6	0.4	-0.3	0.3
Hair/balding pattern: Pattern 2	0.1	0.2	0.6	0.2	0.2	0.7	0.2	0.3	-0.1	0.6	0.8	-0.6	0.3
Had menopause	0.1	0.1	1.0	-0.1	0.3	0.1	0.0	0.1	0.1	1.0	-0.1	-0.6	-0.0
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.7	0.2	0.2	0.2	0.3	0.5	0.8	0.8	0.1	0.1	0.3
Arm fat percentage (right)	0.1	0.4	1.6	0.2	0.2	-0.6	-0.1	-0.3	-1.3	0.0	-0.3	-1.3	-0.7
Alcohol intake versus 10 years previously	0.1	0.1	0.5	0.2	-0.4	0.1	0.7	0.4	0.3	0.3	-0.1	-0.2	0.1
Depression (self-reported)	0.1	0.2	0.5	0.4	0.7	0.2	0.4	0.4	0.7	-0.0	0.2	0.2	0.5
Length of working week for main job	0.1	0.1	0.4	-0.0	0.4	0.6	0.4	-0.2	0.1	-0.0	0.2	-0.6	0.5
Hair/balding pattern: Pattern 4	0.1	0.3	0.5	0.6	0.7	0.3	0.7	0.6	0.7	-0.7	0.3	0.5	0.6
Birth weight of first child	0.1	0.3	1.0	-0.3	0.2	0.2	-0.6	-0.8	-1.0	0.0	-0.1	0.7	-0.5
Peak expiratory flow (PEF)	0.1	0.3	0.5	-0.7	-0.3	-0.6	-0.7	-0.6	0.0	-0.7	-0.6	0.5	-0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	1.1	0.0	0.3	-0.3	-0.1	-0.4	-1.1	0.4	0.1	-1.0	-0.5
High blood pressure (siblings)	0.1	0.1	0.3	0.1	0.3	0.5	0.6	0.2	0.4	-0.4	0.1	-0.4	0.3
Medication: Omeprazole	0.1	0.1	0.6	-0.2	0.4	-0.0	-0.0	-0.3	-0.2	0.8	-0.3	-0.4	0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.4	-0.2	-0.2	0.4	-0.1	-0.1	0.1	-0.6	0.2	-0.4	0.3
Leg fat mass (right)	0.1	0.5	1.8	-0.0	0.5	-0.7	-0.3	-0.5	-1.3	0.6	-0.6	-1.3	-0.8
Number of full sisters	0.1	0.1	0.4	-0.2	-0.5	-0.2	-0.3	-0.6	-0.6	0.3	-0.2	0.2	-0.2
Arm fat percentage (left)	0.1	0.3	1.5	0.4	0.5	-0.3	0.1	-0.0	-1.0	0.5	-0.1	-1.2	-0.4
Average weekly red wine intake	0.1	0.2	0.8	0.3	0.6	0.3	0.0	-0.1	0.5	-0.1	0.2	0.9	0.4
Diabetes diagnosed by doctor	0.1	0.1	0.7	0.5	0.4	0.2	0.5	0.3	-0.4	0.1	0.1	-0.9	-0.0
Eye problems/disorders: Cataract	0.1	0.1	0.4	0.2	0.4	0.3	-0.1	0.0	-0.2	0.6	0.3	-0.3	0.2
Commuting to job workplace: Public transport	0.1	0.1	0.9	-0.3	-0.4	-0.3	-0.1	-0.2	-0.1	-0.9	-0.2	-0.5	-0.2
Medication: Paracetamol	0.1	0.2	0.7	0.5	-0.1	0.9	0.6	0.0	-0.2	0.7	0.6	-0.1	0.5
Medication: Atorvastatin	0.1	0.1	0.6	0.2	-0.5	-0.3	-0.1	0.1	-0.0	-0.0	0.2	0.7	-0.0
Ever smoked	0.1	0.1	0.3	-0.5	-0.2	-0.1	-0.5	-0.4	-0.2	-0.5	-0.4	0.4	-0.3
Pack years of smoking	0.1	0.2	0.7	-0.2	0.8	-0.0	0.4	-0.5	0.1	-0.3	-0.4	-0.7	0.4
Impedance of whole body	0.1	0.7	3.3	-0.9	-1.1	-0.1	-0.5	-0.6	-0.7	-1.8	-0.2	-1.0	-0.3
Leg fat mass (left)	0.1	0.5	1.4	0.1	0.6	-0.8	-0.3	-0.4	-1.1	0.6	-0.5	-1.2	-0.7
Fasting Glucose	0.0	0.0	0.2	-0.1	-0.2	0.3	0.2	0.0	0.2	0.5	-0.2	-0.3	0.1
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	-0.1	-0.2	0.3	-0.0	-0.1	-0.0	-0.2	-0.2	-0.2	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	0.1	0.3	0.1	0.4	-0.5	-0.1	-0.4	-0.1	-0.0	0.2
Qualifications: CSEs or equivalent	0.0	0.0	0.2	-0.2	0.1	-0.0	0.1	-0.0	0.4	0.3	-0.3	-0.1	-0.1
Falls in the last year	0.0	0.0	0.1	0.2	-0.0	-0.0	0.3	-0.1	-0.2	-0.2	0.0	-0.2	0.0
Asthma	0.0	0.1	0.2	0.0	-0.4	-0.3	-0.3	-0.1	-0.5	-0.2	-0.2	0.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.1	-0.3	-0.1	-0.3	-0.2	-0.2	0.0	-0.3	-0.3	-0.0	-0.1
Emphysema/chronic bronchitis	0.0	0.1	0.2	-0.1	-0.5	0.2	0.2	0.2	0.4	-0.2	0.0	-0.1	0.3
Suffer from ‘nerves’	0.0	0.0	0.1	-0.1	0.0	-0.2	-0.1	-0.3	-0.4	-0.3	-0.1	-0.3	-0.3
Asthma (self-reported)	0.0	0.0	0.1	0.3	-0.0	-0.1	-0.1	0.1	-0.3	-0.2	0.0	0.3	-0.2
Diastolic blood pressure, automated reading	0.0	0.1	0.9	0.2	0.9	0.1	0.4	0.3	0.4	0.0	0.0	-0.0	0.2
Commuting to job workplace: Cycle	0.0	0.1	0.3	-0.0	-0.5	0.2	0.1	0.1	0.3	0.3	0.2	0.1	0.1

Hub : Genes

ZSWIM1

Models

Trait associations