TWAS hub - TIGD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3520	0.0470	2.0e-15	0.270	0.197	0.255	0.266	0.269	8.2e-33	1.8e-23	6.7e-31	2.4e-32	1.2e-32
2	TCGA	Breast Invasive Carcinoma	0.0539	0.0214	3.1e-07	0.042	0.038	0.039	NA	0.041	5.5e-09	2.5e-08	1.4e-08	NA	8.1e-09
3	TCGA	Cervical Squamous Cell Carcinoma	0.1180	0.0680	6.5e-03	0.053	0.012	0.020	NA	0.029	1.3e-03	7.7e-02	3.4e-02	NA	1.4e-02
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0754	0.0341	7.2e-05	0.056	0.039	0.041	NA	0.045	6.6e-07	3.2e-05	1.8e-05	NA	7.3e-06
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0636	0.0308	8.5e-04	0.033	0.020	0.010	NA	0.024	1.1e-04	2.1e-03	2.5e-02	NA	8.8e-04
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0900	0.0380	6.9e-05	0.068	0.073	0.041	NA	0.070	1.0e-04	5.6e-05	2.0e-03	NA	8.2e-05
7	TCGA	Brain Lower Grade Glioma	0.0796	0.0380	1.1e-04	0.049	0.029	0.039	NA	0.040	2.7e-06	2.8e-04	2.5e-05	NA	2.3e-05
8	TCGA	Lung Squamous Cell Carcinoma	0.0857	0.0452	3.8e-03	0.029	0.024	0.021	NA	0.019	2.6e-04	8.0e-04	1.5e-03	NA	2.6e-03
9	TCGA	Prostate Adenocarcinoma	0.0823	0.0362	1.4e-04	0.059	0.052	0.042	NA	0.050	9.0e-07	3.8e-06	2.8e-05	NA	5.1e-06
10	TCGA	Stomach Adenocarcinoma	0.1370	0.0690	6.2e-04	0.063	0.046	0.038	NA	0.053	2.3e-05	2.8e-04	8.7e-04	NA	1.1e-04
11	TCGA	Thyroid Carcinoma	0.1240	0.0520	2.2e-04	0.010	0.026	0.028	NA	0.011	3.5e-02	1.3e-03	8.1e-04	NA	2.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Illnesses of mother	8.4	10.3	14.2	-3.5	-3.5	-3.4	-3.6	-3.5	-1.4	-3.5	-2.6	-3.1	-3.8	-2.8
Myopia	7.5	10.9	22.6	-2.6	1.9	-4.0	-2.7	-4.0	-4.8	-4.3	-0.7	-4.3	-3.2	-0.5
Alzheimer’s Disease (in mother)	5.2	6.1	7.5	2.7	2.0	2.5	2.7	2.6	1.4	2.5	2.6	2.7	2.7	2.3
Medication for hormone replacement therapy	3.5	3.9	5.5	-2.3	-1.8	-1.6	-2.3	-1.9	-0.2	-2.1	-2.3	-1.7	-2.1	-2.3
Qualifications: CSEs or equivalent	3.5	4.6	6.6	-2.5	-0.4	-2.4	-2.5	-2.5	-1.5	-2.3	-1.8	-2.4	-2.6	-1.8
Pulse wave reflection index	3.4	4.3	7.3	-2.0	-0.6	-2.1	-2.1	-2.1	-2.0	-1.9	-2.2	-2.7	-1.8	-2.5
Eye problems/disorders: None of the above	3.2	3.7	6.7	1.8	-1.1	2.2	1.8	2.2	2.4	2.1	1.1	2.6	1.9	1.3
Heart disease (mother)	3.2	3.9	4.9	2.2	1.6	2.1	2.1	2.0	1.1	1.9	2.2	2.1	2.1	1.9
Pulse rate	3.0	5.0	10.1	2.1	-0.1	2.4	2.3	2.3	2.5	2.1	3.2	2.8	1.9	1.6
Financial difficulties in last 2 years	2.8	3.8	6.8	1.7	-0.1	2.3	1.6	1.8	2.4	1.9	2.2	2.6	1.6	1.9
Falls in the last year	2.8	3.8	5.5	-2.1	-0.6	-1.8	-2.3	-2.2	-1.3	-2.2	-2.1	-2.0	-2.1	-2.1
Emphysema/chronic bronchitis	2.8	3.2	6.8	1.8	2.6	1.2	2.0	1.7	-0.0	1.4	1.6	1.9	1.7	2.3
Pulse rate, automated reading	2.8	9.0	29.6	2.0	-2.0	3.7	2.1	3.1	5.4	2.8	1.8	4.0	2.1	1.2
Heart disease (siblings)	2.8	3.4	4.7	2.2	1.8	2.1	2.0	2.0	1.0	2.0	1.3	1.6	2.0	2.0
Medication: Blood pressure	2.6	4.6	7.3	2.5	2.0	2.4	2.4	2.5	1.2	2.4	1.3	1.9	2.7	1.6
Fractured/broken bones in last 5 years	2.6	3.3	4.8	-2.1	-2.0	-1.9	-2.1	-2.1	-0.9	-2.1	-1.0	-1.6	-2.2	-1.7
Alzheimer’s Disease (including proxy)	2.5	3.6	4.9	2.2	2.2	1.8	2.1	2.0	0.6	2.0	1.3	1.8	2.2	2.0
Diabetes (mother)	2.5	3.2	6.1	1.8	1.2	1.7	1.8	1.7	0.7	2.2	2.4	2.5	1.9	0.9
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	6.2	-2.1	-0.4	-1.4	-2.1	-1.7	-0.3	-1.9	-2.2	-1.7	-1.8	-2.5
Medication: Allopurinol	2.3	3.1	5.8	1.6	-0.9	1.8	1.6	1.9	2.4	2.0	1.7	2.4	1.3	1.2
Medication: Co-codamol	2.2	2.6	3.7	1.7	-0.4	1.7	1.6	1.7	1.9	1.9	1.7	1.9	1.4	1.2
Relative age voice broke	2.1	3.2	14.0	0.6	-2.5	1.8	0.6	1.2	3.7	1.0	1.8	2.3	0.5	-0.4
Medication: Aspirin	2.1	2.7	6.0	2.1	1.5	1.4	2.0	1.7	0.5	1.6	1.1	1.1	1.7	2.5
Mother’s age at death	2.1	2.6	3.7	1.7	0.4	1.9	1.7	1.8	1.9	1.5	1.8	1.7	1.6	1.1
Stomach or abdominal pain in last month	2.0	2.5	5.3	1.7	1.1	1.3	1.8	1.7	1.0	1.6	2.3	1.8	1.6	1.1
Medication: Amlodipine	2.0	2.8	4.1	1.8	0.9	1.9	1.8	2.0	1.6	1.8	1.4	2.0	1.8	1.0
Supplements: Glucosamine	1.9	2.4	6.5	-1.7	-0.3	-1.4	-1.8	-1.6	-1.2	-1.4	-1.7	-1.2	-1.3	-2.5
Number of incorrect matches in round	1.9	3.1	5.7	1.9	2.4	1.8	1.9	2.0	0.6	1.9	0.9	1.7	2.1	1.4
Pain all over the body in last month	1.9	2.0	2.8	1.6	1.6	1.4	1.6	1.7	1.1	1.2	1.2	1.7	1.5	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	3.7	-1.9	-0.5	-1.9	-1.8	-1.8	-1.4	-1.8	-1.5	-1.6	-1.8	-0.8
Medication: Omeprazole	1.8	2.2	3.5	1.7	1.3	1.6	1.7	1.7	0.5	1.8	1.3	1.5	1.9	0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	11.4	-2.1	-3.4	-1.8	-2.1	-2.1	-0.2	-2.1	-0.5	-0.7	-2.5	-1.6
Past tobacco smoking	1.7	3.1	4.7	-2.1	-2.1	-1.4	-2.1	-1.8	0.3	-1.8	-1.4	-1.3	-2.2	-1.9
Had menopause	1.7	2.1	8.0	0.9	-1.1	1.5	0.9	1.2	2.8	1.2	1.7	1.8	0.6	-0.3
Illnesses of father: None of the above (group 1)	1.7	2.1	3.3	1.6	0.9	1.6	1.5	1.6	1.2	1.6	0.7	1.6	1.5	1.8
Ever taken oral contraceptive pill	1.7	1.9	3.5	-1.3	-0.5	-1.7	-1.4	-1.5	-1.9	-1.3	-1.4	-1.4	-1.2	-1.1
LDL Cholesterol	1.6	2.6	5.6	0.0	1.2	-1.9	-1.6	-2.1	-2.4	-2.0	-0.6	-1.9	-1.6	0.0
Average weekly fortified wine intake	1.6	1.9	5.0	0.9	-1.1	1.4	0.9	1.3	2.2	1.1	1.4	2.1	0.9	1.0
Blood clot in the leg (DVT)	1.6	2.0	5.0	1.2	0.4	1.9	1.2	1.7	2.2	1.6	0.7	1.7	1.4	0.5
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	3.9	-1.9	-1.5	-1.6	-1.8	-1.8	-0.5	-1.7	-0.9	-1.5	-1.9	-2.0
Smoking status: Previous	1.6	2.4	3.8	1.9	1.8	1.3	1.8	1.6	-0.3	1.7	1.0	0.9	1.9	1.9
Average weekly spirits intake	1.5	1.9	3.5	-1.2	-0.3	-1.8	-1.2	-1.6	-1.9	-1.6	-0.2	-1.7	-1.3	-1.2
Relative age of first facial hair	1.5	3.1	13.5	-0.4	-3.5	0.9	-0.5	0.3	3.7	0.1	0.9	2.1	-0.7	-1.4
Vitamin and mineral supplements	1.5	2.0	2.5	1.4	1.6	1.5	1.5	1.5	1.0	1.5	1.3	1.4	1.5	1.5
Medication: Ibuprofen	1.5	1.8	3.1	-1.5	0.6	-1.2	-1.5	-1.3	-0.8	-1.6	-1.5	-1.5	-1.2	-1.8
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	2.9	1.6	1.5	1.2	1.6	1.5	0.0	1.5	1.5	1.3	1.7	0.8
HDL Cholesterol	1.4	2.4	4.9	0.0	-0.2	1.9	1.8	2.1	1.5	2.2	0.5	2.0	1.9	0.0
Mouth/teeth dental problems: Dentures	1.4	2.4	5.2	1.6	0.6	1.5	1.8	1.8	0.9	1.9	1.5	2.3	1.6	0.8
Back pain experienced in last month	1.4	2.0	7.5	1.4	0.7	1.2	1.2	1.0	1.2	1.1	2.7	1.7	0.9	1.4
Illnesses of siblings	1.3	1.8	3.5	-1.2	-0.6	-1.7	-1.1	-1.5	-1.9	-1.4	-0.5	-1.8	-1.3	-0.7
Asthma	1.3	2.6	4.0	-1.6	-0.6	-2.0	-1.7	-1.9	-1.7	-1.8	-1.3	-2.0	-2.0	-0.1
Medication: Aspirin	1.3	1.7	3.9	1.7	0.6	1.2	1.6	1.4	0.7	1.3	1.0	1.0	1.2	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	2.3	-1.2	-0.7	-1.4	-1.2	-1.5	-1.2	-1.5	0.1	-1.2	-1.4	-1.4
Basal cell carcinoma (self-reported)	1.3	1.5	2.8	1.1	1.7	1.6	1.2	1.5	1.2	1.2	-0.7	1.0	1.4	0.5
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	3.9	1.0	0.3	1.6	1.1	1.5	2.0	1.4	0.7	1.6	1.2	0.5
Pack years of smoking	1.3	1.8	6.7	0.9	-1.2	1.6	1.0	1.3	2.6	1.2	1.1	1.7	0.7	0.2
Medication: Levothyroxine sodium	1.2	2.0	3.1	-1.7	-0.8	-1.5	-1.8	-1.6	-1.0	-1.6	-1.1	-0.8	-1.6	-1.7
Hearing aid user	1.2	1.4	2.3	1.4	0.6	1.1	1.4	1.5	1.0	1.4	0.5	0.7	1.3	1.4
Smoking Status	1.1	2.6	6.5	1.6	2.5	0.3	1.7	0.9	-2.3	1.1	1.5	0.8	1.8	1.8
Supplements: Zinc	1.1	1.2	3.8	1.1	2.0	0.5	1.1	0.7	-0.5	0.5	1.9	1.1	1.0	0.7
Multivitamins +/- minerals	1.1	1.4	2.6	-1.1	-0.7	-1.4	-1.1	-1.5	-1.6	-1.3	-0.6	-1.4	-1.2	-0.8
Mouth/teeth dental problems	1.1	1.7	3.4	-1.4	-0.1	-1.3	-1.5	-1.4	-0.8	-1.6	-1.3	-1.9	-1.3	-0.6
Comparative height size at age 10	1.1	5.9	38.6	-1.6	-6.2	-0.2	-1.6	-0.8	3.3	-0.7	-0.9	1.6	-2.1	-1.4
Medication for cholesterol	1.1	1.7	3.1	1.4	-0.0	1.6	1.5	1.5	1.8	1.3	1.2	0.8	1.4	1.2
Schizophrenia (2018)	1.0	2.0	3.3	-1.8	-1.6	-0.8	-1.8	-1.4	0.9	-1.8	-0.7	-0.7	-1.8	-1.5
Maternal smoking around birth	1.0	1.4	5.5	-0.7	1.8	-1.3	-0.7	-1.1	-2.3	-1.2	-0.6	-1.1	-0.6	-0.1
Serious illness, injury or assault to yourself	1.0	1.2	3.4	1.1	0.6	1.0	1.1	1.1	0.7	0.9	1.0	1.0	1.1	1.8
Lung cancer (father)	1.0	1.2	3.9	-1.0	-2.0	-0.4	-0.9	-0.5	0.8	-0.6	-1.1	-0.6	-0.9	-1.9
Had major operations	1.0	1.1	2.8	1.1	-0.5	0.9	1.0	1.1	1.4	0.9	0.9	1.0	0.7	1.7
Qualifications: nursing, teaching	1.0	1.5	5.7	-0.8	-1.6	-1.4	-1.0	-0.9	-1.0	-0.7	-2.4	-1.4	-0.9	-0.5
Eye problems/disorders: Cataract	1.0	1.1	2.0	-1.1	0.8	-1.2	-1.0	-1.3	-1.4	-1.4	0.2	-1.1	-1.2	-0.1
Schizophrenia vs Biploar Disorder	0.9	1.2	2.6	-1.3	-1.0	-0.7	-1.3	-1.1	0.2	-1.0	-1.1	-0.7	-1.2	-1.6
Height	0.9	16.7	112.4	-2.7	-10.6	-0.8	-2.6	-1.5	5.3	-1.6	-0.6	2.1	-4.0	-1.6
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.7	-0.8	0.9	-1.0	-0.8	-1.0	-1.7	-1.1	-0.8	-1.1	-0.6	-0.6
High blood pressure (mother)	0.9	1.3	3.1	1.2	1.5	0.8	1.2	1.0	-0.5	1.3	0.7	0.5	1.4	1.8
Hair/balding pattern: Pattern 2	0.9	1.2	5.1	-0.3	2.3	-0.6	-0.4	-0.3	-1.1	-0.3	-1.8	-1.4	-0.2	-0.8
Qualifications: A levels/AS levels or equivalent	0.9	1.9	4.0	-1.3	-1.4	-1.6	-1.2	-1.2	-1.3	-1.2	-2.0	-1.7	-1.2	-0.2
Standing height	0.9	9.2	61.0	-2.3	-7.8	-1.0	-2.2	-1.6	3.2	-1.6	-0.7	1.1	-3.2	-1.5
Peak expiratory flow (PEF)	0.9	2.1	4.1	-1.3	-1.8	-1.6	-1.4	-1.7	-0.9	-1.5	-0.6	-2.0	-1.8	-0.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.0	-0.9	-0.5	-1.3	-0.8	-1.0	-1.1	-1.2	-0.9	-1.4	-1.1	-0.6
Chest pain or discomfort	0.9	1.2	2.2	-1.0	-1.2	-1.5	-1.0	-1.2	-1.0	-1.4	-0.8	-1.1	-1.4	0.0
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.1	-0.8	1.0	-1.3	-0.7	-1.0	-1.3	-1.0	-0.4	-1.3	-0.8	-1.4
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.9	-1.0	0.3	-1.3	-1.0	-1.1	-1.1	-1.1	-1.4	-1.2	-1.2	0.3
Asthma (self-reported)	0.9	1.7	2.6	-1.2	-0.3	-1.6	-1.3	-1.6	-1.5	-1.4	-1.0	-1.6	-1.6	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	7.7	-0.5	1.2	-1.4	-0.5	-1.0	-2.8	-0.8	-1.1	-2.3	-0.4	-0.4
Bipolar Disorder or Schizophrenia	0.8	1.8	3.1	-1.7	-1.4	-0.9	-1.7	-1.4	0.5	-1.7	-0.8	-0.5	-1.6	-1.8
Alzheimer’s Disease (in father)	0.8	0.8	1.6	-1.0	-0.4	-0.8	-1.0	-1.0	-1.2	-0.7	-1.2	-0.7	-0.6	-1.1
Lung FVC	0.8	3.9	18.9	1.7	4.3	0.3	1.7	0.8	-2.6	1.0	1.2	-0.7	1.8	2.0
Diabetes (father)	0.8	0.9	5.5	-0.2	-0.8	1.1	-0.2	0.5	2.3	0.5	-0.3	1.0	0.1	-1.2
Townsend deprivation index at recruitment	0.8	1.1	3.5	0.7	1.9	0.9	0.6	0.5	0.5	0.4	1.6	1.5	0.6	0.8
Nervous feelings	0.8	1.5	2.8	1.0	1.4	1.4	1.1	1.1	0.9	1.0	1.1	1.5	1.2	1.7
Had other major operations	0.8	1.0	3.5	0.5	-0.4	1.2	0.5	1.2	1.9	1.3	-0.8	0.9	1.0	-0.2
Number of full brothers	0.8	1.0	3.2	0.9	1.8	0.1	0.8	0.4	-1.6	0.7	0.5	0.3	1.0	1.3
Angina (self-reported)	0.8	1.0	5.0	0.5	1.8	-0.6	0.5	0.0	-2.2	0.0	-0.2	-0.6	0.5	1.1
Alcohol intake frequency.	0.8	1.9	3.4	1.3	0.9	1.7	1.2	1.4	1.6	1.3	1.6	1.8	1.1	1.0
Supplements: Vitamin C	0.8	1.0	1.8	-1.0	-1.4	-0.9	-1.1	-0.9	-0.0	-1.1	-1.1	-0.7	-1.2	-1.0
Loneliness, isolation	0.8	1.1	1.8	-1.3	-1.3	-0.6	-1.4	-0.9	0.7	-1.0	-1.3	-0.5	-1.3	-1.0
Financial situation satisfaction	0.8	1.0	1.6	0.6	1.1	1.3	0.8	0.9	1.2	0.9	1.2	1.1	1.0	0.8
Qualifications: None of the above	0.7	1.6	4.2	0.9	2.0	1.4	1.1	1.2	0.7	1.0	0.9	1.3	1.3	1.3
Prospective memory result	0.7	0.9	3.4	0.1	-1.8	0.8	0.3	0.7	1.8	0.9	-0.5	0.7	0.3	0.9
Pulse wave Arterial Stiffness index	0.7	0.8	2.9	-0.6	-1.7	0.4	-0.5	-0.1	1.6	-0.0	0.4	0.8	-0.6	-1.0
Birth weight	0.7	1.5	7.3	-0.8	-2.7	-1.2	-0.9	-1.1	-0.8	-0.7	-0.8	-1.3	-1.1	-0.3
High blood pressure (siblings)	0.7	1.0	3.6	0.6	-0.2	1.1	0.5	0.9	1.9	0.9	0.6	1.6	0.5	0.8
Arm fat-free mass (right)	0.7	3.5	23.5	-1.3	-4.8	-0.6	-1.2	-0.9	2.1	-0.8	0.2	1.1	-1.9	-0.9
Medication: Seretide 50 evohaler	0.7	0.8	1.6	-0.7	-0.1	-1.3	-0.8	-1.1	-1.1	-1.2	0.1	-0.8	-1.2	0.3
Mean time to correctly identify matches	0.7	1.4	3.8	1.0	0.0	1.5	1.0	1.4	1.9	1.2	-0.2	1.4	1.1	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.8	0.6	-1.1	1.0	0.6	1.0	1.4	1.0	0.2	1.3	0.8	0.2
Arm predicted mass (right)	0.7	3.4	22.8	-1.4	-4.8	-0.8	-1.3	-1.0	1.8	-0.9	-0.1	0.9	-2.0	-0.7
Illnesses of father: High blood pressure	0.7	0.8	2.2	-1.1	-0.9	-0.5	-1.1	-0.7	0.1	-0.7	-1.5	-0.9	-0.8	-1.0
Number of operations (self-reported)	0.7	1.0	2.2	0.9	-0.3	1.0	0.8	1.0	1.5	1.1	1.1	1.5	0.8	0.7
Unable to work because of sickness or disability	0.7	1.0	2.0	0.8	1.1	1.0	0.8	0.9	1.0	0.7	1.4	1.4	0.7	0.5
Respiratory disease	0.6	1.3	2.3	-1.2	-0.4	-1.4	-1.2	-1.4	-1.1	-1.2	-0.9	-1.2	-1.5	0.0
Lung FEV1/FVC ratio	0.6	3.2	5.5	-2.1	-1.7	-1.7	-2.1	-1.9	-0.8	-1.8	-1.4	-1.3	-1.9	-2.4
Angina	0.6	0.8	3.4	0.6	1.7	-0.4	0.6	0.1	-1.8	0.1	0.1	-0.5	0.5	1.2
Pack years adult smoking proportion	0.6	0.9	4.3	0.1	-1.5	0.9	0.2	0.5	2.1	0.4	0.6	1.1	-0.0	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	6.2	-0.6	0.8	-1.4	-0.6	-1.0	-2.5	-0.7	-1.3	-1.6	-0.6	-0.1
Sitting height	0.6	4.0	30.5	-1.2	-5.5	-0.4	-1.1	-0.9	2.0	-0.8	0.3	0.8	-1.8	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.3	0.8	-0.4	0.9	0.8	0.8	1.2	0.7	1.1	1.5	0.5	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	6.6	-0.6	1.2	-1.4	-0.5	-1.0	-2.6	-0.7	-0.9	-1.3	-0.4	-0.1
Father’s age at death	0.6	0.8	1.7	1.0	-0.3	0.8	1.0	0.9	0.7	0.8	1.3	1.2	0.9	0.3
Ever highly irritable/argumentative for 2 days	0.6	0.8	2.6	0.7	0.5	0.7	0.8	0.8	0.0	0.9	0.9	1.6	0.9	0.9
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.1	-0.7	-0.9	-1.5	-0.8	-1.2	-1.4	-1.0	-0.1	-1.3	-1.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.9	-0.9	-0.6	-0.6	-0.9	-0.8	0.1	-0.8	-1.4	-1.0	-1.0	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.7	0.8	0.8	0.4	0.8	0.7	0.6	0.7	1.3	1.1	0.4	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.4	-0.6	-0.2	-1.0	-0.7	-0.7	-1.2	-0.8	-0.9	-1.2	-0.5	-0.8
Commuting to job workplace: Walk	0.6	0.6	2.3	0.6	1.5	0.2	0.6	0.3	-1.3	0.5	0.0	-0.5	1.1	-0.2
Pain type(s) experienced in last month: Hip pain	0.6	0.8	4.4	-0.4	-1.8	0.4	-0.5	0.0	2.1	0.1	-0.2	0.7	-0.5	-0.2
Medication: Bendroflumethiazide	0.6	0.9	1.9	1.1	0.3	0.8	1.0	1.0	-0.0	1.1	0.4	1.4	1.1	1.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.4	0.6	-1.6	0.9	0.5	0.7	1.2	0.7	0.2	0.8	0.5	0.4
Ovarian Cancer	0.5	0.6	1.1	0.9	0.1	0.8	0.9	0.8	0.1	1.0	0.7	1.1	0.9	0.7
Coronary Artery Disease (CAD)	0.5	0.6	3.1	0.0	-0.2	-0.6	0.0	-0.5	-1.3	-0.4	-1.8	-1.1	-0.4	0.0
Severe depression (siblings)	0.5	0.6	1.9	-1.1	-0.6	-0.3	-0.8	-0.5	0.9	-0.9	0.1	-0.0	-0.7	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.9	-0.9	-1.4	-0.3	-0.8	-0.7	0.9	-0.6	0.5	0.7	-1.1	0.1
Taking other prescription medications	0.5	0.7	1.3	1.1	1.0	0.5	1.0	1.0	-0.4	1.1	0.1	0.5	1.0	1.1
Hearing difficulty/problems with background noise	0.5	0.7	1.9	0.8	0.4	0.8	0.8	0.9	1.0	0.8	0.8	1.4	0.7	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	1.6	-0.8	-1.3	-0.4	-0.9	-0.8	1.0	-0.9	0.9	0.3	-1.2	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	2.4	-1.2	-1.4	-1.5	-1.3	-1.5	-1.1	-1.3	-0.9	-1.5	-1.5	-0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.6	0.6	-1.0	0.6	0.5	0.4	0.8	0.6	1.3	1.2	0.2	1.1
Medication: Paracetamol	0.5	0.8	1.3	1.0	0.9	0.9	0.9	0.8	0.6	0.6	1.1	0.6	0.8	1.0
Worry too long after embarrassment	0.5	0.8	1.4	-1.2	-0.2	-0.9	-1.1	-1.0	-0.4	-1.0	-1.0	-0.5	-1.0	-0.6
Leg pain on walking	0.5	0.7	3.3	0.2	-1.8	0.4	0.1	0.3	1.4	0.4	0.3	1.2	-0.1	0.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.6	-0.7	0.0	-0.8	-0.8	-0.8	-0.7	-0.7	-0.5	-0.8	-0.8	-1.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.2	-0.8	-1.1	-0.6	-0.9	-0.6	0.5	-0.5	-1.1	-0.7	-0.9	-0.4
Arm fat-free mass (left)	0.5	2.7	17.4	-1.1	-4.2	-0.3	-1.0	-0.6	2.3	-0.5	0.4	1.4	-1.6	-0.4
Pain experienced in last month	0.5	0.8	1.6	-0.8	-0.1	-0.9	-0.6	-0.8	-1.3	-0.9	-1.0	-1.0	-0.4	-1.1
Arm predicted mass (left)	0.5	2.5	15.8	-1.0	-4.0	-0.2	-0.9	-0.5	2.2	-0.4	0.3	1.4	-1.5	-0.4
Age at First Birth	0.4	0.7	4.6	-0.3	-2.1	0.0	-0.5	-0.1	1.1	-0.2	-0.8	-0.1	-0.5	-0.4
Rheumatoid Arthritis	0.4	0.5	1.2	-0.8	0.4	-0.6	-0.8	-0.7	0.0	-0.8	-1.1	-0.6	-0.9	-0.3
Schizophrenia (2014)	0.4	0.9	1.6	-1.2	-0.7	-0.2	-1.2	-0.7	1.1	-1.0	-0.8	0.3	-1.1	-1.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.6	0.0	-0.9	-0.7	0.0	-0.7	-0.6	-0.5	-1.3	-0.7	-0.8	0.0
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.5	-0.2	-1.6	0.4	-0.3	0.1	1.5	-0.1	0.2	1.0	-0.4	0.5
Hayfever, allergic rhinitis or eczema	0.4	1.0	2.2	1.2	1.1	0.8	1.1	0.8	-0.0	0.8	1.5	0.9	1.0	0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	2.4	-0.2	0.2	-1.0	-0.1	-0.5	-1.6	-0.3	0.2	-0.9	-0.4	0.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.9	0.8	1.4	0.3	0.8	0.5	-0.9	0.5	0.4	0.0	0.9	0.9
Medication: Simvastatin	0.4	0.5	1.8	0.9	0.4	0.3	0.8	0.4	-0.7	0.7	1.3	0.5	0.8	0.6
Trunk fat-free mass	0.4	2.4	16.6	-1.0	-4.1	-0.3	-0.9	-0.6	1.9	-0.6	0.2	1.1	-1.5	-0.5
Trunk predicted mass	0.4	2.4	16.5	-0.9	-4.1	-0.3	-0.8	-0.5	2.0	-0.5	0.2	1.1	-1.4	-0.5
Tense / ‘highly strung’	0.4	0.6	1.1	-1.0	-0.8	-0.5	-1.0	-0.8	0.2	-1.0	-1.0	-0.1	-1.0	-0.3
Loud music exposure frequency	0.4	0.4	1.0	0.6	1.0	0.5	0.7	0.6	-0.4	0.8	0.3	0.3	0.9	-0.3
Glaucoma (self-reported)	0.4	0.4	2.5	0.1	1.1	-0.5	0.0	-0.4	-1.6	-0.4	0.5	-0.5	0.1	0.3
Number of children fathered	0.4	0.5	0.8	0.9	0.6	0.6	0.9	0.9	0.6	0.6	0.7	0.4	0.8	0.5
Number of full sisters	0.4	0.5	1.7	-0.7	-0.9	-0.6	-0.6	-0.6	-0.4	-0.6	-0.3	-0.3	-0.5	-1.3
Family relationship satisfaction	0.4	0.4	1.1	0.4	-0.2	0.9	0.5	0.8	1.1	0.7	-0.0	0.9	0.7	0.2
Illnesses of father: Heart disease	0.4	0.6	1.5	-0.4	-0.2	-1.1	-0.4	-0.8	-1.2	-0.9	0.3	-1.1	-0.8	0.1
Whole body fat-free mass	0.4	2.0	13.7	-0.8	-3.7	-0.2	-0.7	-0.5	1.9	-0.5	0.5	1.2	-1.3	-0.2
Long-standing illness, disability or infirmity	0.4	0.7	1.8	0.9	1.4	0.4	0.9	0.7	-0.9	0.9	0.5	0.5	1.0	0.5
Average weekly champagne plus white wine intake	0.4	0.6	2.6	-0.5	-1.6	-0.2	-0.5	-0.3	0.8	-0.5	0.2	-0.2	-0.4	-1.4
Wears glasses or contact lenses	0.4	0.5	3.1	0.7	0.5	0.2	0.7	0.3	-0.3	0.3	0.7	-0.3	0.4	1.7
Eye problems/disorders: Glaucoma	0.4	0.5	0.7	-0.8	0.1	-0.7	-0.8	-0.8	-0.8	-0.8	-0.6	-0.8	-0.7	-0.8
Reaction Time	0.3	0.6	1.0	0.7	0.8	0.9	0.6	1.0	0.9	0.6	-0.6	0.9	0.8	0.2
Body Mass Index (BMI) (2010)	0.3	0.4	1.7	0.0	1.3	-0.1	0.5	0.2	-1.2	0.1	0.4	0.3	0.6	0.9
Fasting Glucose	0.3	0.4	1.1	0.4	0.5	1.1	-0.6	-0.4	-0.7	-0.5	-0.6	0.4	0.8	0.4
HbA1C	0.3	0.4	1.0	-0.8	-0.4	-0.9	-0.5	-0.4	-0.5	-0.3	-1.0	-0.5	-0.4	-0.7
Lupus	0.3	0.5	1.8	0.5	0.1	0.6	0.6	0.5	0.0	0.7	0.7	1.0	0.6	1.4
Ulcerative Colitis	0.3	0.5	3.7	0.1	1.9	-0.1	0.1	0.1	-0.8	0.0	-0.8	-0.7	0.4	0.0
Heel T-Score	0.3	2.3	7.7	1.5	2.8	1.0	1.6	1.3	-0.6	1.4	0.6	0.6	1.7	2.1
Number of treatments/medications taken	0.3	0.6	3.0	0.1	1.6	-0.5	0.0	-0.2	-1.7	-0.2	-0.9	-0.3	0.1	0.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.2	-0.5	-0.2	-0.7	-0.5	-0.5	-0.8	-0.3	-1.1	-0.8	-0.6	-0.1
Current tobacco smoking	0.3	0.5	2.1	0.5	1.1	-0.1	0.6	0.2	-0.9	0.3	1.4	0.9	0.6	0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.3	0.2	-0.2	0.5	0.3	0.3	0.4	0.2	1.1	1.0	0.3	-0.6
Trunk fat mass	0.3	1.2	5.6	-0.4	-2.4	0.1	-0.4	-0.1	1.8	0.1	0.6	1.6	-0.8	-0.0
Medication: Ramipril	0.3	0.4	1.0	-0.1	0.7	-0.6	-0.2	-0.4	-1.0	-0.4	-0.8	-1.0	-0.2	0.4
Weight	0.3	1.7	8.6	-0.7	-2.9	-0.0	-0.6	-0.3	2.1	-0.2	0.8	1.6	-1.2	-0.1
Time employed in main current job	0.3	0.3	0.9	0.5	0.1	0.6	0.6	0.6	0.3	0.6	0.5	0.8	0.4	1.0
Hair/balding pattern: Pattern 3	0.3	0.5	1.6	0.0	-0.4	0.7	0.1	0.3	1.1	0.2	1.2	1.2	0.3	-0.5
Noisy workplace	0.3	0.4	1.3	0.6	0.9	0.5	0.6	0.6	0.2	0.5	-0.1	0.6	0.5	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	2.5	-0.2	-1.6	0.1	-0.3	-0.1	0.5	0.2	-0.1	0.3	-0.2	0.0
Medication: Cholesterol lowering	0.3	0.4	1.6	0.6	1.1	0.4	0.5	0.4	-0.4	0.3	-0.1	0.2	0.7	1.3
Depression (self-reported)	0.3	0.4	1.0	-0.4	-0.1	-0.5	-0.5	-0.6	-0.5	-0.5	-1.0	-0.7	-0.7	0.6
Length of working week for main job	0.3	0.3	1.8	0.4	0.2	-0.0	0.4	0.1	-0.5	0.4	0.8	0.3	0.1	1.3
Exposure to tobacco smoke at home	0.3	0.3	1.1	-0.3	0.2	-0.4	-0.5	-0.5	-0.4	-0.5	-0.4	-1.1	-0.4	-0.9
Breastfed as a baby	0.3	0.4	1.4	-0.2	0.3	-0.6	-0.0	-0.3	-1.2	-0.3	-0.8	-1.0	-0.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	2.0	-0.7	-1.4	-0.3	-0.6	-0.3	0.9	-0.5	-0.4	0.2	-0.8	0.1
Hair/balding pattern: Pattern 4	0.3	0.7	2.6	0.8	0.0	0.5	0.8	0.6	0.4	0.7	1.6	0.7	0.6	1.3
Birth weight of first child	0.3	0.5	1.8	-0.1	-1.3	-0.9	-0.2	-0.6	-1.1	-0.4	0.6	-0.4	-0.5	0.2
Exposure to tobacco smoke outside home	0.3	0.4	1.6	0.2	-1.2	0.5	0.2	0.3	1.3	0.3	0.4	0.3	0.1	0.1
Wheeze or whistling in the chest in last year	0.3	0.6	2.1	0.3	1.4	-0.0	0.3	0.1	-0.5	0.0	1.0	1.0	0.0	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.5	0.6	0.9	0.0	0.6	0.3	-0.6	0.4	1.2	0.1	0.5	-0.2
Age at first live birth	0.3	0.5	3.8	-0.4	-1.9	-0.4	-0.3	-0.1	-0.1	-0.1	-0.6	-0.5	-0.3	-0.7
Pulse wave peak to peak time	0.3	0.4	1.5	0.3	1.1	-0.5	0.2	-0.1	-1.2	-0.2	-0.5	-0.8	0.2	0.7
Health satisfaction	0.3	0.3	1.5	0.2	-0.0	0.2	0.2	0.1	0.6	0.0	1.2	0.8	-0.0	1.1
Migraine (self-reported)	0.3	0.3	2.3	0.4	1.5	0.0	0.4	0.2	-0.7	0.1	0.6	-0.1	0.4	0.3
Mood swings	0.3	0.5	2.2	-0.7	-1.5	-0.5	-0.6	-0.6	0.6	-0.8	0.1	0.0	-1.0	0.3
Ever had bowel cancer screening	0.3	0.3	0.8	0.7	-0.3	0.5	0.6	0.5	0.9	0.5	0.8	0.4	0.4	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.9	0.9	0.0	0.8	0.7	0.9	1.0	0.8	0.3	0.6	0.8	0.4
Breast cancer (self-reported)	0.3	0.3	0.9	0.5	-0.8	0.7	0.3	0.6	0.9	0.7	-0.2	0.6	0.5	0.3
Osteoporosis (self-reported)	0.3	0.4	2.2	-0.2	-1.5	-0.0	-0.3	-0.0	0.6	0.2	-0.8	-0.0	-0.4	-0.7
Osteoarthritis (self-reported)	0.3	0.4	1.2	0.5	0.5	0.4	0.5	0.6	0.8	0.5	0.6	0.9	0.3	1.1
Smoking status: Current	0.3	0.5	2.0	0.4	1.0	-0.2	0.5	0.1	-1.1	0.1	1.4	0.7	0.5	0.1
Whole body water mass	0.3	1.9	13.0	-0.7	-3.6	-0.2	-0.7	-0.5	1.8	-0.4	0.5	1.2	-1.3	-0.1
Miserableness	0.3	0.5	1.5	0.7	-0.1	0.7	0.7	0.8	0.6	0.7	-0.1	0.8	0.7	1.2
Medication: Paracetamol	0.3	0.5	2.0	0.6	1.4	0.5	0.6	0.4	-0.0	0.2	1.1	0.3	0.6	0.4
Ever smoked	0.3	0.5	1.0	0.8	0.7	0.4	0.8	0.7	-0.6	0.7	0.4	0.4	1.0	0.7
Basal metabolic rate	0.3	1.9	12.3	-0.8	-3.5	-0.3	-0.7	-0.5	1.8	-0.5	0.6	1.3	-1.3	-0.2
Average weekly beer plus cider intake	0.3	0.4	1.7	-0.4	0.5	-0.7	-0.3	-0.7	-1.3	-0.6	-0.0	-1.0	-0.4	0.2
Supplements: Calcium	0.3	0.3	0.8	-0.5	-0.6	-0.3	-0.6	-0.5	0.0	-0.5	-0.1	-0.6	-0.6	-0.9
Depression (Nagel 2018)	0.2	0.4	1.7	-0.5	-1.3	0.1	-0.3	-0.1	1.3	-0.1	-0.1	0.2	-0.6	-0.1
Worry (Nagel 2018)	0.2	0.5	1.3	0.7	1.1	0.6	0.8	0.6	0.1	0.4	0.7	0.7	0.7	0.7
Irritable Bowel Disease (IBD)	0.2	0.4	2.7	0.6	1.6	0.4	0.5	0.5	-0.4	0.5	-0.0	0.2	0.8	0.3
Blood Platelet Count	0.2	2.1	8.1	-1.6	-2.8	-0.7	-1.6	-1.1	1.4	-1.2	-0.4	0.7	-1.9	-0.8
Blood Red Count	0.2	1.5	7.1	1.0	2.7	1.2	1.1	1.0	0.3	0.8	1.1	0.5	1.3	0.6
Hair Pigment	0.2	6.0	15.4	1.8	-0.2	3.0	1.9	2.6	3.9	2.3	2.1	3.8	2.0	0.7
Hand grip strength (left)	0.2	0.4	1.6	-0.5	-0.4	-1.0	-0.4	-0.6	-1.3	-0.6	-0.3	-0.7	-0.5	-0.5
Sensitivity / hurt feelings	0.2	0.3	0.9	-0.7	-1.0	-0.4	-0.6	-0.4	0.2	-0.3	-0.8	-0.0	-0.5	-0.5
Hearing difficulty/problems: Yes	0.2	0.3	0.7	0.5	0.0	0.6	0.5	0.6	0.6	0.5	0.2	0.9	0.6	-0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	0.6	-0.1	0.5	0.5	0.6	0.2	0.6	0.2	0.9	0.5	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.8	-0.7	-0.2	-0.4	-0.6	-0.5	0.1	-0.5	0.0	-0.1	-0.6	-0.9
Ever had hysterectomy (womb removed)	0.2	0.2	1.0	-0.4	-1.0	-0.5	-0.3	-0.3	-0.0	-0.1	-0.1	0.2	-0.4	-0.3
Medication: Metformin	0.2	0.3	0.7	-0.1	0.4	-0.8	-0.3	-0.5	-0.9	-0.6	0.2	-0.2	-0.4	-0.7
Impedance of leg (right)	0.2	1.1	4.3	-1.0	-2.1	-0.3	-1.0	-0.5	1.1	-0.4	-1.4	0.0	-1.0	-1.0
Leg fat-free mass (left)	0.2	1.2	7.2	-0.4	-2.7	-0.1	-0.4	-0.3	1.4	-0.3	1.0	1.3	-0.9	0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.6	-0.5	-0.5	-0.7	-0.6	-0.5	-0.4	-0.3	-0.8	-0.5	-0.5	-0.1
Medication: Atenolol	0.2	0.3	0.9	0.0	0.7	-0.5	-0.1	-0.1	-0.8	-0.1	-0.9	-0.8	0.0	-0.4
Impedance of leg (left)	0.2	1.2	3.9	-1.1	-2.0	-0.5	-1.1	-0.7	0.7	-0.5	-1.5	-0.2	-1.2	-1.1
Leg predicted mass (left)	0.2	1.3	7.3	-0.4	-2.7	-0.0	-0.4	-0.2	1.6	-0.3	1.0	1.4	-0.9	0.1
Alcohol usually taken with meals	0.2	0.4	1.3	-0.6	-1.0	-0.4	-0.5	-0.2	0.4	-0.2	-0.8	-0.4	-0.4	-1.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.0	0.0	-0.8	0.2	0.1	0.2	0.7	0.1	0.4	1.0	-0.0	-0.2
Heart attack	0.2	0.3	0.5	0.5	0.6	0.7	0.5	0.7	0.7	0.7	-0.2	0.5	0.5	0.2
Fluid intelligence score	0.2	0.5	1.8	-0.1	0.9	-0.6	-0.2	-0.6	-1.4	-0.7	0.9	-0.7	-0.1	-0.3
Hip circumference	0.2	0.9	4.2	-0.4	-2.1	0.1	-0.3	-0.1	1.7	-0.0	0.7	1.2	-0.8	0.5
Number of live births	0.2	0.3	1.1	-0.0	0.9	-0.1	-0.1	-0.3	-0.8	-0.3	1.1	0.3	0.0	-0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.0	-0.6	-0.8	-1.1	-0.7	-1.0	-1.2	-0.8	-0.6	-1.4	-0.9	0.2
Medication: Lansoprazole	0.2	0.2	2.0	0.4	0.1	0.1	0.4	0.2	-0.1	0.0	1.4	0.3	0.2	0.3
Headache pain in last month	0.2	0.3	0.6	-0.6	-0.8	-0.7	-0.6	-0.7	-0.2	-0.4	0.2	-0.5	-0.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	-0.8	-0.5	-0.6	-0.9	-0.7	-0.5	-0.6	-0.6	-0.3	-0.6	-0.8
Shortness of breath walking on level ground	0.2	0.2	0.7	0.2	-0.6	0.2	0.0	0.1	0.4	0.3	0.0	0.8	-0.1	0.8
Qualifications: College or University degree	0.2	0.7	1.8	-0.9	-0.9	-0.7	-0.9	-0.7	-0.1	-0.9	-1.3	-0.8	-0.8	-0.5
Neck or shoulder pain in last month	0.2	0.2	1.2	-0.3	-0.8	0.4	-0.2	0.2	1.1	0.5	-0.2	0.5	-0.1	0.0
Whole body fat mass	0.2	0.9	4.1	-0.5	-2.0	0.0	-0.5	-0.2	1.6	-0.0	0.5	1.2	-0.9	0.1
Leg fat mass (right)	0.2	0.7	2.7	-0.3	-1.6	0.3	-0.3	0.1	1.6	0.2	0.3	1.4	-0.6	-0.0
Suffer from ‘nerves’	0.2	0.3	0.5	0.4	0.7	0.5	0.4	0.5	-0.1	0.5	-0.0	0.6	0.6	0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.7	-0.4	-0.8	-0.3	-0.5	-0.3	0.0	-0.1	-0.5	-0.1	-0.4	-0.9
Knee pain experienced in last month	0.2	0.3	1.0	-0.4	-0.9	0.2	-0.3	0.0	0.8	0.1	-0.2	0.4	-0.2	-1.0
Illnesses of siblings: Diabetes	0.2	0.2	1.1	0.2	0.1	0.4	0.2	0.3	0.0	0.5	-0.1	1.0	0.4	-0.7
Leg fat-free mass (right)	0.2	1.2	7.0	-0.5	-2.6	-0.2	-0.4	-0.4	1.3	-0.4	1.0	1.2	-0.9	0.1
Medication: Gliclazide	0.2	0.2	0.8	0.4	0.3	0.2	0.4	0.4	0.3	0.5	-0.7	-0.1	0.3	0.9
Leg predicted mass (right)	0.2	1.1	6.8	-0.5	-2.6	-0.2	-0.4	-0.4	1.3	-0.4	1.0	1.2	-0.9	0.1
Commuting to job workplace: Public transport	0.2	0.3	0.5	0.6	0.6	0.2	0.6	0.4	-0.3	0.4	0.7	-0.1	0.7	0.5
Medication: Blood pressure	0.2	0.4	1.8	-0.3	1.0	-0.8	-0.5	-0.7	-1.4	-0.4	-0.4	0.0	-0.5	0.3
Medication: Lisinopril	0.2	0.2	0.5	0.5	0.6	0.6	0.5	0.6	-0.0	0.7	-0.2	0.5	0.7	-0.0
Medication: Atorvastatin	0.2	0.2	1.0	0.4	1.0	0.4	0.3	0.5	0.3	0.4	-0.3	0.6	0.5	0.3
Risk taking	0.2	0.3	1.1	-0.5	-0.1	-0.7	-0.5	-0.7	-1.0	-0.6	0.2	-0.5	-0.4	0.1
Diastolic blood pressure, automated reading	0.2	0.6	3.8	-0.0	1.9	-0.2	-0.0	-0.1	-0.8	-0.1	-0.4	-1.2	0.2	-0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.6	0.4	0.3	0.7	0.4	0.6	0.8	0.6	-0.2	0.5	0.4	0.2
Alcohol drinker status: Previous	0.2	0.2	1.6	0.2	0.5	0.4	0.2	0.1	0.2	0.1	1.3	0.6	0.1	0.1
Leg fat mass (left)	0.2	0.6	2.3	-0.3	-1.5	0.2	-0.3	0.0	1.4	0.2	0.5	1.4	-0.6	0.1
Bipolar Disorder (2018)	0.1	0.2	0.6	-0.5	-0.3	-0.4	-0.5	-0.4	-0.3	-0.5	-0.2	0.1	-0.2	-0.8
Depressed Affect (Nagel 2018)	0.1	0.1	1.0	-0.1	-1.0	0.1	0.0	0.1	0.6	-0.0	-0.1	0.1	-0.1	0.0
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.3	0.2	-0.5	0.0	0.2	0.0	0.6	-0.2	1.1	0.2	-0.2	1.1
Crohns Disease (2017)	0.1	0.2	0.3	0.5	0.5	0.4	0.5	0.4	0.2	0.4	0.5	0.4	0.5	0.6
Ulcerative Colitis (UC)	0.1	0.3	2.0	0.3	1.4	0.1	0.2	0.2	-0.6	0.2	-0.4	-0.1	0.5	0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.6	0.1	0.1	0.4	0.1	0.0	0.8	-0.1	1.3	0.6	-0.0	0.4
Prostate Cancer	0.1	0.2	0.8	0.0	0.8	-0.0	-0.1	-0.1	0.0	0.0	0.2	0.8	-0.2	0.9
Mean Putamen Volume	0.1	0.1	0.4	0.2	0.6	0.1	0.1	0.1	-0.2	-0.1	-0.4	0.2	0.1	0.2
Neuroticism (2016)	0.1	0.2	0.9	0.2	-0.3	0.3	0.3	0.2	1.0	0.1	0.9	0.2	-0.1	0.1
Triglycerides	0.1	0.1	0.3	0.0	0.5	-0.0	-0.2	-0.3	-0.3	-0.4	0.6	-0.2	-0.1	0.0
Blood Eosinophil Count	0.1	0.9	2.5	1.1	-0.1	0.7	1.2	1.1	0.1	1.2	0.5	0.8	1.0	1.6
Blood White Count	0.1	0.8	2.1	-1.0	-1.5	-0.6	-1.0	-0.7	0.8	-0.8	-0.5	0.9	-1.2	-0.4
BMI	0.1	0.4	1.5	0.1	1.2	0.4	0.2	0.2	0.6	0.1	1.1	0.8	0.2	0.1
Waist Hip Ratio (WHR)	0.1	0.3	1.9	0.2	1.4	0.4	0.2	0.3	-0.4	0.4	-0.1	0.6	0.6	-0.5
Systolic Blood Pressure	0.1	0.5	2.3	-0.9	-0.0	-0.6	-0.8	-0.6	-0.1	-0.5	-1.5	-0.8	-0.7	-0.4
Cardiovascular Disease	0.1	0.5	2.1	-0.4	0.5	-0.9	-0.6	-0.8	-1.4	-0.6	0.1	-0.3	-0.6	-0.5
Hypothyroidism (self reported)	0.1	0.3	0.6	-0.6	-0.8	-0.5	-0.7	-0.5	-0.1	-0.4	-0.7	-0.3	-0.7	-0.7
Chronotype (morning person)	0.1	0.2	1.0	0.3	1.0	0.2	0.3	0.4	-0.2	0.2	0.6	0.3	0.5	-0.3
Systolic blood pressure, automated reading	0.1	0.2	1.1	0.2	1.0	0.5	0.3	0.4	0.7	0.4	0.2	-0.2	0.3	-0.1
Trunk fat percentage	0.1	0.6	1.9	-0.1	-1.2	0.2	-0.1	0.0	1.3	0.2	0.8	1.4	-0.5	0.3
Hand grip strength (right)	0.1	0.3	1.1	0.2	-0.7	-0.7	0.3	-0.2	-1.1	-0.0	0.5	-0.4	-0.1	0.4
Fed-up feelings	0.1	0.2	1.0	-0.4	-1.0	-0.4	-0.4	-0.2	0.2	-0.3	-0.6	-0.2	-0.4	-0.2
Age when periods started (menarche)	0.1	0.2	1.2	-0.4	0.1	0.4	-0.3	0.0	0.6	-0.1	-0.7	0.2	0.0	-1.1
High blood pressure	0.1	0.4	1.3	0.7	1.2	0.2	0.5	0.3	-0.5	0.5	0.5	0.4	0.6	0.9
Body mass index (BMI)	0.1	0.3	1.1	0.3	0.5	0.3	0.3	0.3	0.6	0.4	1.1	1.1	0.2	0.6
Waist circumference	0.1	0.4	2.2	-0.0	-0.4	0.4	0.0	0.2	1.3	0.3	0.6	1.5	-0.2	0.2
Allergy	0.1	0.2	0.5	-0.5	-0.6	-0.3	-0.5	-0.3	0.0	-0.3	-0.6	-0.4	-0.3	-0.7
Diabetes (self-reported)	0.1	0.2	0.9	0.5	0.7	-0.1	0.4	0.2	-0.1	-0.0	1.0	0.3	0.1	0.3
Neuroticism score	0.1	0.1	0.9	0.1	0.3	0.3	0.2	0.3	0.2	0.1	-0.3	0.4	0.2	0.9
Arm fat percentage (right)	0.1	0.3	1.4	0.2	1.2	0.2	0.2	0.2	0.2	0.3	0.8	0.9	0.1	0.7
Alcohol intake versus 10 years previously	0.1	0.1	0.7	0.3	0.8	-0.1	0.2	0.1	-0.3	-0.1	0.5	0.2	0.2	-0.0
Worrier / anxious feelings	0.1	0.2	0.8	0.4	0.9	0.5	0.5	0.6	0.4	0.3	0.1	0.4	0.5	0.0
Happiness	0.1	0.2	1.1	-0.3	-1.1	-0.1	-0.1	0.0	0.6	-0.0	-0.4	-0.0	-0.3	-0.2
Arm fat mass (right)	0.1	0.3	1.4	-0.3	-0.5	0.0	-0.2	-0.1	0.8	0.1	0.7	1.2	-0.5	0.4
Gout (self-reported)	0.1	0.2	0.7	0.3	-0.6	0.1	0.3	0.4	0.3	0.6	-0.0	0.5	0.1	0.8
Forced vital capacity (FVC), Best measure	0.1	0.5	0.9	-0.4	-0.6	-0.9	-0.5	-0.9	-0.9	-0.7	0.1	-0.8	-0.8	0.0
Body fat percentage	0.1	0.5	1.8	-0.2	-0.9	0.3	-0.1	0.1	1.4	0.3	0.7	1.3	-0.4	0.2
Leg fat percentage (right)	0.1	0.5	2.8	-0.3	-0.8	0.5	-0.3	0.2	1.7	0.4	0.0	1.3	-0.3	-0.3
Medication for pain relief, constipation, heartburn	0.1	0.2	1.3	-0.5	-1.1	-0.3	-0.3	-0.3	0.2	-0.2	-0.1	-0.2	-0.3	-0.5
Overall health rating	0.1	0.3	1.2	0.1	-0.5	0.1	-0.1	-0.1	0.8	-0.3	1.1	0.6	-0.4	0.4
Age at last live birth	0.1	0.2	1.4	-0.1	-1.2	0.2	0.0	0.2	0.6	0.1	0.2	0.1	0.0	-0.2
Hypertension (Self-reported)	0.1	0.3	1.2	0.7	1.1	0.1	0.4	0.2	-0.6	0.3	0.7	0.3	0.5	0.7
Arm fat percentage (left)	0.1	0.3	1.0	0.2	0.7	0.2	0.2	0.2	0.2	0.4	0.8	1.0	0.1	0.6
Average weekly red wine intake	0.1	0.2	0.9	-0.2	-0.9	-0.1	-0.1	0.1	0.2	0.0	-0.9	0.2	0.1	-0.4
Diabetes diagnosed by doctor	0.1	0.1	0.5	0.2	0.4	-0.5	0.1	-0.1	-0.4	-0.2	0.7	0.2	-0.3	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	0.3	-0.5	0.1	0.4	0.2	0.1	0.2	0.5	0.4	0.2	0.7
Arm fat mass (left)	0.1	0.4	1.8	-0.1	-0.7	0.1	-0.0	0.1	0.8	0.2	0.8	1.4	-0.3	0.7
Number of self-reported non-cancer illnesses	0.1	0.2	0.4	0.6	0.1	0.3	0.5	0.4	-0.2	0.6	0.6	0.6	0.5	0.6
Guilty feelings	0.1	0.2	0.8	-0.6	-0.9	-0.0	-0.5	-0.3	0.4	-0.3	-0.2	0.2	-0.3	-0.1
High cholesterol (Self-reported)	0.1	0.3	1.5	-0.1	-1.2	0.1	-0.2	-0.1	0.7	0.0	0.7	0.5	-0.2	-0.0
Alcohol drinker status: Never	0.1	0.1	0.5	-0.4	-0.0	0.3	-0.4	-0.0	0.7	-0.1	-0.6	0.2	-0.2	-0.1
Leg fat percentage (left)	0.1	0.4	2.2	-0.1	-0.6	0.5	-0.1	0.3	1.5	0.5	0.4	1.2	-0.2	-0.1
Irritability	0.1	0.1	0.7	-0.2	-0.7	-0.2	-0.1	-0.2	-0.2	-0.3	0.1	-0.1	-0.2	0.8
Ever depressed for a whole week	0.1	0.1	0.2	-0.2	-0.5	-0.3	-0.0	-0.0	-0.5	0.1	-0.0	0.0	0.0	-0.4
Commuting to job workplace: Cycle	0.1	0.2	0.7	0.3	-0.3	-0.0	0.3	0.2	0.1	0.0	0.7	0.5	0.1	0.9
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.8	-0.7	-1.3	-0.2	-0.5	-0.3	0.7	-0.5	-0.3	-0.2	-0.6	-0.7
Cholesterol lowering medication	0.1	0.2	0.8	0.4	-0.0	0.1	0.3	0.2	-0.1	0.4	0.9	0.6	0.1	-0.0
Impedance of whole body	0.1	0.6	1.9	-0.8	-1.4	-0.4	-0.8	-0.5	0.4	-0.5	-1.1	-0.3	-0.9	-0.7
Neuroticism (Nagel 2018)	0.0	0.1	0.1	0.2	-0.3	0.2	0.3	0.3	0.4	0.1	0.4	0.4	0.1	0.3
Major Depression (MDD)	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.6	0.0	-0.1	0.2	0.0	0.0
Breast Cancer	0.0	0.1	0.2	-0.1	-0.3	-0.3	-0.1	-0.2	-0.5	-0.2	-0.2	-0.3	-0.1	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	-0.0	0.0	0.1	0.2	0.4	0.0
Primary Biliary Cirrhosis	0.0	0.1	0.2	-0.2	-0.4	-0.4	-0.0	-0.2	-0.2	-0.2	0.0	-0.2	-0.3	0.2
Allergy or Eczema	0.0	0.1	0.9	0.1	0.5	0.1	-0.0	-0.1	0.1	-0.2	0.9	0.3	-0.0	0.2
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.2	0.0	0.0	-0.1	-0.0	-0.1	0.2	-0.2	0.2	0.4	-0.2	-0.2
Neuroticism	0.0	0.1	0.7	0.2	0.3	0.1	0.3	0.1	-0.3	-0.2	-0.0	-0.0	0.1	0.8
Tanning	0.0	0.4	0.7	-0.5	0.6	-0.7	-0.6	-0.6	-0.7	-0.8	-0.8	-0.6	-0.4	-0.4
Forced vital capacity (FVC)	0.0	0.1	0.9	0.4	-0.3	-0.1	0.2	-0.0	-0.3	0.1	0.5	-0.2	0.0	0.9
Impedance of arm (right)	0.0	0.1	0.4	-0.3	0.6	-0.1	-0.2	-0.2	-0.1	-0.4	-0.4	-0.3	-0.2	-0.1
Impedance of arm (left)	0.0	0.0	0.1	-0.0	-0.1	-0.0	-0.1	-0.0	0.0	-0.1	-0.4	-0.0	-0.1	-0.1
Comparative body size at age 10	0.0	0.1	0.3	-0.1	0.0	-0.1	-0.0	-0.1	-0.6	0.2	0.1	0.3	0.1	0.4
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.2	0.1	-0.4	0.2	0.1	0.2	0.0	0.4	0.0	0.0	0.2	-0.2
Friendships satisfaction	0.0	0.0	0.2	0.0	0.1	0.2	0.2	0.3	-0.1	0.0	-0.4	-0.2	0.3	0.1
Mineral and other dietary supplements	0.0	0.0	0.3	0.1	0.3	0.2	0.2	-0.0	-0.2	-0.1	0.5	-0.2	0.1	0.1
Age started oral contraceptive pill	0.0	0.0	0.2	0.1	-0.1	-0.0	0.2	0.2	-0.0	0.4	-0.1	0.3	0.2	-0.0

Hub : Genes

TIGD1

Models

Trait associations