Hub : Genes

SPON2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2830	0.0440	0.0e+00	0.166	0.201	0.261	0.241	0.236	1.1e-19	6.7e-24	1.1e-31	5.6e-29	2.6e-28
2	GTEx	Brain Putamen basal ganglia	0.3780	0.1050	1.2e-03	0.115	NA	0.024	NA	0.065	1.2e-03	NA	8.8e-02	NA	1.3e-02
3	GTEx	Nerve Tibial	0.0927	0.0456	9.0e-03	0.015	NA	0.001	NA	0.017	2.6e-02	NA	2.5e-01	NA	2.1e-02
4	GTEx	Skin Sun Exposed Lower leg	0.1440	0.0520	1.5e-03	0.011	NA	0.029	NA	0.043	3.8e-02	NA	1.9e-03	NA	1.7e-04
5	METSIM	Adipose	0.0618	0.0186	6.9e-07	0.057	0.049	0.047	0.048	0.053	5.9e-09	7.3e-08	1.3e-07	8.1e-08	2.2e-08
6	ROSMAP	Brain Pre-frontal Cortex	0.4051	0.0560	0.0e+00	0.255	0.263	0.285	0.299	0.302	1.4e-32	1.1e-33	8.1e-37	5.9e-39	2.0e-39
7	YFS	Blood	0.0250	0.0102	6.9e-04	0.011	0.004	0.011	0.009	0.008	9.9e-05	1.3e-02	1.1e-04	5.7e-04	7.9e-04
8	TCGA	Breast Invasive Carcinoma	0.0317	0.0171	3.7e-04	0.003	0.016	0.022	NA	0.014	8.6e-02	2.7e-04	2.1e-05	NA	4.8e-04
9	TCGA	Prostate Adenocarcinoma	0.1529	0.0523	1.4e-09	0.096	0.101	0.111	NA	0.100	3.1e-10	9.5e-11	1.1e-11	NA	1.2e-10

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.5	2.4	9.4	0.2	-0.7	-3.1	0.9	-2.3	1.6	-1.6	0.3	0.5
Bipolar Disorder or Schizophrenia	1.7	4.1	14.1	1.4	-0.9	-3.8	1.9	-1.6	2.6	-1.7	-1.7	1.1
Depressed Affect (Nagel 2018)	1.2	2.5	7.9	-2.2	0.6	2.2	-1.1	-0.0	-2.8	-1.1	0.7	-1.1
Depression (Nagel 2018)	0.8	1.2	2.6	-1.2	-1.3	1.6	-0.8	0.5	-1.6	-1.1	1.0	0.3
Intelligence (Savage-Jansen 2018)	1.2	3.6	23.8	0.2	-4.9	0.1	0.5	2.1	0.4	0.4	-0.4	1.9
Neuroticism (Nagel 2018)	0.5	1.3	3.5	-0.7	-0.1	1.5	-1.5	-0.7	-1.1	-1.9	0.9	-0.5
Schizophrenia (2018)	1.3	2.7	6.2	1.7	-0.6	-2.3	1.7	-0.2	2.0	-0.8	-2.5	1.1
Schizophrenia vs Biploar Disorder	0.5	0.6	2.0	0.7	-0.4	1.4	-0.5	0.4	-0.2	1.4	-0.7	-0.1
Worry (Nagel 2018)	0.8	1.6	4.6	1.0	0.5	-1.1	-0.4	-2.0	1.8	-2.1	0.3	-0.1
Alzheimer’s Disease (in mother)	1.3	1.5	5.4	1.1	1.6	-1.4	0.2	0.8	2.3	-0.3	-0.4	1.1
Alzheimer’s Disease (in father)	0.8	0.9	2.1	-1.5	-1.0	0.6	1.0	0.3	-1.2	-0.3	1.3	0.1
Alzheimer’s Disease (including proxy)	0.4	0.6	1.6	0.1	0.3	-0.5	0.7	1.3	1.2	-0.1	0.4	1.2
Crohns Disease (2017)	0.5	1.1	2.8	1.5	0.3	-0.8	0.3	-1.2	1.5	0.2	-1.7	-0.5
Irritable Bowel Disease (IBD)	0.7	1.7	5.0	1.8	-0.2	-1.6	-0.5	-1.4	1.4	-0.0	-2.2	0.1
Ulcerative Colitis (UC)	0.8	1.5	4.2	1.6	-0.6	-1.9	-0.9	-0.6	0.9	-0.2	-2.0	0.8
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	-0.1
Reaction Time	0.6	1.1	7.0	0.3	2.6	0.4	1.1	0.6	0.4	0.0	-0.8	0.4
Verbal and Numeric Reasoning (VNR)	1.2	2.8	14.1	0.5	-3.8	1.0	0.1	2.6	0.6	-0.1	0.0	1.5
Breast Cancer	1.7	4.1	7.7	-2.1	-2.2	0.4	-1.9	-2.8	-2.5	-0.9	1.5	-2.6
Ovarian Cancer	0.2	0.3	1.8	-0.2	-0.5	0.2	0.2	0.6	0.1	-0.0	-1.3	0.2
Prostate Cancer	1.0	1.4	4.6	-0.8	-1.3	2.1	-0.6	0.8	-1.5	1.2	-0.5	-0.4
Age at First Birth	0.2	0.3	1.2	0.2	0.6	0.4	-0.1	-1.0	-0.2	0.3	0.1	-1.1
Bipolar Disorder (2011)	0.5	0.5	3.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-2.0	-0.4
Body Mass Index (BMI) (2010)	0.9	1.3	5.8	0.4	2.4	-1.0	0.1	-0.8	0.9	0.6	-0.7	-1.6
Coronary Artery Disease (CAD)	0.8	1.0	2.9	0.3	-0.5	-0.8	1.7	-0.7	1.3	-0.0	-0.3	1.6
Crohns Disease (2012)	0.8	1.4	3.1	1.6	1.4	-1.4	0.9	-0.1	1.4	0.1	-1.8	0.2
Mean Putamen Volume	2.0	2.3	6.7	0.5	-0.9	1.5	-0.9	0.7	-1.0	2.0	-2.6	-2.1
Fasting Glucose	2.1	2.5	8.1	2.8	1.0	-1.2	-1.1	0.4	2.0	1.0	-2.2	1.1
HbA1C	3.0	3.3	8.6	2.9	2.4	-0.9	-2.1	-0.5	2.6	1.6	-0.8	-0.1
HDL Cholesterol	0.4	0.7	2.1	1.2	-0.0	-0.2	-1.0	0.9	0.7	0.5	-1.5	0.6
LDL Cholesterol	1.5	2.4	4.9	-0.4	-1.0	2.2	-1.7	-1.1	-1.8	2.2	0.1	-1.7
Lupus	0.8	1.2	4.1	0.1	1.3	-1.8	2.0	-0.1	1.2	-0.2	-0.6	0.4
Neuroticism (2016)	0.7	1.0	2.5	-1.6	0.9	1.1	-0.3	0.5	-1.6	-0.8	0.7	0.2
Primary Biliary Cirrhosis	3.0	4.3	15.0	2.3	1.1	-3.9	0.0	-0.7	3.5	-1.3	-0.9	1.3
Rheumatoid Arthritis	1.3	1.8	4.1	0.2	1.8	-1.2	0.9	1.8	1.3	-0.5	-1.3	2.0
Schizophrenia (2014)	1.0	2.2	4.6	1.6	-0.7	-1.9	1.1	-0.6	1.9	-1.0	-2.2	1.4
Triglycerides	0.2	0.4	1.9	-1.0	0.0	0.4	-0.1	0.1	-1.4	0.2	-0.2	0.0
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.8	0.3	-0.2	-1.4	-1.0	-1.0	-0.1	0.2	-1.2	-0.7
Ulcerative Colitis	1.3	2.0	7.7	1.1	-0.5	-2.8	-0.9	-1.1	1.0	-0.6	-2.2	0.4
Blood Eosinophil Count	0.3	2.2	6.4	-1.4	-2.0	-1.7	1.0	-0.6	-0.1	-1.2	1.2	2.5
Blood Platelet Count	0.4	4.3	16.6	-1.7	0.4	-1.4	1.7	-1.5	-0.3	-3.2	4.1	1.2
Blood Red Count	0.3	2.6	6.6	-2.0	0.1	2.6	-0.4	-1.8	-2.0	-0.3	2.2	-0.7
Blood White Count	0.4	2.9	10.9	-1.9	-0.0	-0.5	1.8	0.2	-0.6	-1.6	2.4	3.3
Heel T-Score	5.4	42.7	153.8	3.9	5.5	-8.3	-2.3	-12.4	2.2	-4.6	3.6	-8.4
BMI	0.5	2.6	13.1	-1.3	0.7	-0.0	0.9	-1.1	-0.4	-2.3	3.6	0.7
Height	0.4	7.0	35.9	-1.1	0.6	-1.8	-0.9	-2.9	-2.9	1.0	-1.9	-6.0
Waist Hip Ratio (WHR)	1.9	8.4	18.8	-2.4	-4.3	4.3	-0.7	1.3	-3.3	4.2	0.2	-1.6
Systolic Blood Pressure	0.3	1.7	4.0	2.0	1.6	-0.9	-0.6	-0.2	1.3	2.0	-1.1	-0.7
Smoking Status	1.4	3.4	8.1	-1.3	1.1	2.8	-1.3	2.8	-2.4	2.1	0.1	-0.5
Allergy or Eczema	0.1	0.4	2.2	-0.6	-1.5	0.2	0.1	-0.4	-0.3	-0.1	-0.5	0.3
Cardiovascular Disease	0.5	1.5	6.1	-0.4	0.4	0.9	-1.5	-1.6	-1.1	0.0	2.5	-0.7
Hypothyroidism (self reported)	0.8	1.8	5.2	-1.1	-1.2	1.2	0.2	-1.6	-1.4	-0.9	2.3	-1.3
Respiratory disease	0.5	1.1	5.4	-0.8	1.1	-0.8	0.9	-0.3	0.1	-0.5	0.8	2.3
Type 2 Diabetes (T2D) (2018)	0.7	1.4	8.5	-0.5	-2.9	-0.1	0.1	1.4	-0.1	-1.0	-0.1	0.7
Lung FEV1/FVC ratio	0.3	1.6	6.5	-0.2	-2.2	0.1	-1.2	0.1	-0.9	-0.7	-0.5	-2.5
Lung FVC	0.4	2.1	8.5	0.7	-1.0	-0.8	0.5	-2.0	1.1	1.6	-0.7	-2.9
Neuroticism	0.3	0.7	2.6	-0.8	-0.2	0.8	0.3	-0.8	-0.1	-1.6	1.0	-0.5
Chronotype (morning person)	2.0	4.5	11.0	1.1	-1.6	-2.8	1.8	-0.7	3.0	-2.3	0.4	3.3
Hair Pigment	0.2	5.0	13.6	3.7	1.9	-3.1	-0.6	-0.3	3.3	0.3	-2.5	0.2
Tanning	0.1	1.3	5.8	-0.5	-0.5	1.6	-1.0	2.4	-1.0	-0.1	0.2	0.9
Hand grip strength (left)	1.3	3.4	11.1	1.0	-0.1	0.5	-1.7	-1.2	-0.7	3.0	-2.2	-3.3
Number of treatments/medications taken	0.4	0.6	4.1	0.3	2.0	-0.4	0.1	0.7	0.5	-0.5	-0.5	-0.3
Average weekly spirits intake	0.8	1.0	2.8	1.1	1.7	-1.0	-1.0	-1.1	0.9	-0.9	0.2	-0.6
Sensitivity / hurt feelings	0.3	0.5	1.3	1.1	0.5	1.2	-1.0	-0.1	0.2	-0.3	-0.2	-1.0
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.4	-0.2	-1.2	0.3	-0.2	0.1	0.2	-0.3	-0.5	0.2
Hearing difficulty/problems: Yes	1.2	1.9	7.8	-1.7	-0.1	-0.2	0.8	1.6	-0.4	-2.8	1.1	1.3
Relative age of first facial hair	0.8	1.6	3.4	1.7	-0.4	1.2	-0.8	1.8	0.7	1.8	-1.2	-0.5
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	4.9	-0.7	0.4	-0.1	2.2	0.1	0.4	0.0	-1.1	0.5
Ever used hormone-replacement therapy (HRT)	1.6	2.0	6.4	-0.1	1.3	1.5	0.2	1.1	-0.7	2.5	-1.5	-2.0
Ever had hysterectomy (womb removed)	2.3	2.6	10.7	-1.1	2.4	1.4	0.5	3.3	-0.4	0.5	-1.0	1.3
Systolic blood pressure, automated reading	0.4	1.1	5.0	0.5	1.4	0.8	0.2	-0.5	0.0	2.2	0.2	-1.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.7	-0.8	-0.4	1.3	-0.4	0.6	-1.1	1.1	0.9	-0.0
Angina	0.5	0.7	1.6	0.4	-0.7	1.3	-1.1	-0.4	0.0	-0.2	-0.9	-1.3
Medication for hormone replacement therapy	0.4	0.4	1.3	0.6	-0.7	0.4	-1.1	0.1	-0.2	1.0	-0.7	-0.4
Vitamin and mineral supplements	0.5	0.6	2.2	0.9	1.5	0.3	-1.3	-0.5	0.4	0.4	-0.2	-0.2
Supplements: Zinc	0.4	0.4	2.0	0.3	0.5	-0.1	-0.4	-0.0	-0.6	1.4	0.2	-0.9
Medication: Co-codamol	1.0	1.2	4.1	1.0	1.7	0.8	-0.6	1.1	0.4	2.0	-0.7	0.2
Medication: Metformin	0.5	0.7	2.4	0.0	-0.8	-0.2	0.5	1.1	0.8	-0.9	-0.2	1.5
Diabetes (father)	2.3	2.8	10.0	-0.6	-2.3	-0.3	2.6	-0.2	1.5	-0.5	-0.1	3.2
Diabetes (mother)	0.7	0.9	2.2	-1.1	-0.4	0.9	1.4	0.1	-0.1	1.3	0.7	1.5
Severe depression (siblings)	0.5	0.6	2.8	0.3	0.9	-0.7	1.7	0.2	0.5	0.2	-0.7	0.2
Pack years adult smoking proportion	0.6	0.9	3.6	-1.0	1.2	1.0	0.4	1.9	-0.9	0.2	0.3	0.6
Impedance of leg (right)	0.8	3.7	6.7	-1.0	-1.9	2.6	-2.2	2.3	-1.8	2.2	-1.0	1.6
Leg fat-free mass (left)	0.6	3.2	7.0	0.1	2.0	-2.6	1.5	-2.6	0.6	-1.1	1.1	-2.3
Trunk fat percentage	0.5	1.9	5.5	-1.8	0.1	1.5	0.9	2.3	-0.9	0.4	1.3	1.7
Hand grip strength (right)	1.7	4.6	18.3	1.1	-0.6	-0.3	-1.7	-2.3	-0.8	2.7	-2.3	-4.3
Townsend deprivation index at recruitment	0.6	0.9	3.0	-1.3	1.0	0.8	0.5	-0.1	-1.1	0.4	1.7	0.1
Current tobacco smoking	1.0	1.6	4.3	-1.2	0.7	1.7	-0.4	2.1	-1.9	0.8	0.5	0.7
Average weekly fortified wine intake	1.1	1.3	4.0	-1.0	1.8	1.4	-0.5	0.2	-0.9	0.3	2.0	0.0
Maternal smoking around birth	1.4	2.0	8.1	-2.1	-0.6	2.0	-0.3	0.4	-2.9	-0.2	0.9	-0.4
Fed-up feelings	0.9	1.6	4.2	-2.0	0.4	1.3	-0.1	0.4	-2.0	-1.7	1.1	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.7	-1.2	-1.0	2.2	-1.6	0.3	-1.9	-0.5	1.1	-0.7
Relative age voice broke	1.2	1.8	6.6	-0.1	-0.2	2.6	-0.7	2.1	-1.1	1.4	-1.0	-0.6
Taking other prescription medications	0.5	0.7	2.7	-0.2	1.7	0.1	1.0	1.0	0.8	-0.4	0.1	1.0
Age when periods started (menarche)	0.2	0.4	1.5	0.0	-0.2	1.1	0.4	0.8	-0.2	1.2	0.1	0.1
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.7	-0.2	1.6	1.4	-1.3	1.6	-1.0	1.3	-1.3	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	3.5	7.8	29.3	1.8	2.4	-2.9	-0.8	-5.4	1.7	-1.9	2.2	-3.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.8	-0.9	-0.6	0.6	-1.1	-1.2	-1.3	-1.0	0.8	-0.6
Qualifications: CSEs or equivalent	0.8	1.0	5.5	-0.8	1.0	-0.0	1.1	-2.3	-0.3	-0.5	0.5	-0.7
Serious illness, injury or assault to yourself	0.3	0.4	1.4	-0.0	1.2	0.0	-1.0	0.3	-0.1	-0.8	-0.7	0.0
High blood pressure	0.2	0.6	2.0	0.0	1.4	-0.4	0.4	-0.9	0.4	-0.5	1.4	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.5	-0.2	-0.7	-0.3	0.3	-0.1	0.2	0.6	-0.4	0.7
Multivitamins +/- minerals	1.6	2.0	6.6	-2.0	-2.6	0.1	1.5	0.2	-1.7	-0.8	1.3	0.4
Stomach or abdominal pain in last month	0.4	0.5	2.3	-0.3	0.9	-0.4	1.5	-0.7	0.7	-0.1	0.2	0.0
Supplements: Glucosamine	1.2	1.6	5.2	-0.5	0.4	-1.7	0.5	-2.3	-0.6	-1.2	0.2	-1.9
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	4.0	-0.8	-2.0	-0.0	0.2	1.6	-0.4	0.2	-0.0	0.5
Medication: Atenolol	0.5	0.7	4.3	0.1	0.1	-0.0	-0.5	-0.4	-0.1	0.3	-1.1	-2.1
Medication: Levothyroxine sodium	1.2	2.0	6.7	-0.8	0.1	-0.8	1.7	-1.6	0.7	-2.6	2.0	-0.5
Sitting height	0.5	3.2	9.6	1.0	0.2	-3.1	-0.9	-2.1	0.4	0.8	-1.9	-3.0
Chronic bronchitis/emphysema (father)	0.3	0.4	2.1	-0.3	0.8	-1.4	0.2	-0.3	-0.2	-0.1	0.5	0.5
High blood pressure (mother)	0.4	0.6	2.4	0.7	-0.1	-0.1	0.4	0.3	0.7	1.5	-1.0	-0.8
Body mass index (BMI)	0.5	2.2	7.9	-0.7	1.0	-1.1	1.8	-1.3	0.7	-1.8	2.8	0.5
Impedance of leg (left)	0.6	2.9	6.4	-0.7	-2.5	1.9	-2.3	1.6	-1.4	1.7	-1.7	0.6
Leg predicted mass (left)	0.6	3.3	7.3	0.1	1.9	-2.7	1.7	-2.7	0.6	-1.2	1.1	-2.3
Trunk fat mass	0.2	1.0	2.8	-1.6	0.5	0.5	1.1	0.8	-0.9	-0.2	1.7	0.5
Waist circumference	0.5	1.8	6.3	-2.0	-0.3	0.3	1.6	-1.0	-1.0	-0.9	2.5	-0.6
Number of incorrect matches in round	0.6	1.0	2.8	0.1	1.7	-1.1	1.5	-0.7	1.1	0.2	-0.0	0.8
Past tobacco smoking	0.4	0.8	1.5	1.2	0.7	-1.0	-0.8	0.2	1.2	-0.4	-1.2	0.8
Alcohol usually taken with meals	0.8	1.3	6.1	-0.3	-0.2	0.0	-1.9	-0.4	-1.3	-0.4	0.1	-2.5
Nervous feelings	0.7	1.3	3.2	1.2	0.6	-0.7	-0.1	-0.4	1.7	-1.8	0.6	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	4.6	-0.8	-0.0	2.1	-1.0	0.8	-1.0	-0.0	0.0	-0.8
Hearing difficulty/problems with background noise	1.9	3.1	7.4	-2.1	2.2	1.3	0.9	0.8	-0.8	-2.5	2.7	0.9
Hair/balding pattern: Pattern 2	0.4	0.5	2.1	0.9	-0.2	-0.8	-0.7	-1.5	0.5	-0.4	0.5	-0.3
Had menopause	0.5	0.7	1.9	-0.5	1.4	0.6	0.3	1.2	-0.4	1.2	0.1	-0.6
Had other major operations	0.6	0.8	2.6	-0.6	0.6	1.1	-0.5	1.6	-0.9	0.9	-0.3	-0.6
Forced vital capacity (FVC)	1.3	5.0	12.6	1.8	-1.6	-2.5	0.0	-3.2	1.6	1.6	-2.2	-3.5
Heel bone mineral density (BMD) T-score, automated (right)	3.6	8.3	37.1	1.3	1.5	-2.5	-0.9	-6.1	0.9	-1.6	2.4	-4.2
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	3.7	-0.7	0.4	0.1	0.9	-1.0	-0.2	-0.4	1.9	-0.0
Qualifications: None of the above	0.9	1.9	9.8	1.3	3.1	0.6	-1.1	0.7	0.8	-0.1	0.0	1.6
Financial difficulties in last 2 years	0.8	1.1	2.2	-0.5	1.1	1.4	-0.7	1.5	-1.2	0.7	-0.8	1.1
Mouth/teeth dental problems	1.2	1.8	6.8	1.7	-0.0	-2.6	-0.7	-1.5	1.7	-0.6	-0.4	-0.2
Heart attack	2.9	3.7	11.6	-1.8	-1.6	3.4	-1.8	2.1	-2.8	0.4	0.5	-0.2
Allergy	0.2	0.5	1.3	1.0	-0.7	0.6	-1.1	0.3	0.1	0.2	-0.6	-0.9
Pain all over the body in last month	1.9	2.0	8.0	-0.5	0.8	1.8	-0.1	2.8	-0.5	1.2	-0.2	2.1
Diabetes (self-reported)	0.7	1.0	3.0	-1.3	-1.2	0.7	0.5	1.7	-0.6	-0.4	0.5	1.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	0.3	0.4	-0.6	0.6	-0.3	0.3	0.1	0.1	0.2
Medication: Ramipril	1.3	1.7	4.6	-1.3	0.8	1.7	-0.7	-0.1	-1.9	-0.2	2.2	-1.1
Medication: Simvastatin	1.4	2.0	4.5	-1.7	-1.3	2.1	-0.0	1.5	-1.8	-0.7	1.5	0.9
Fluid intelligence score	1.6	3.3	23.3	0.9	-4.8	-0.9	0.3	0.4	1.7	-1.0	-0.6	0.5
Illnesses of siblings	0.9	1.2	2.5	-0.9	-1.2	-0.1	-1.3	-1.2	-1.3	-0.0	1.2	-1.6
Neuroticism score	0.4	0.8	3.5	-0.7	-0.1	0.9	-0.1	-0.7	-0.2	-1.9	1.4	-0.2
Weight	0.5	2.6	5.7	-1.0	1.4	-1.8	1.6	-2.4	-0.1	-1.3	2.1	-1.6
Impedance of arm (right)	2.0	9.5	37.8	-0.5	-1.0	3.9	-1.4	6.1	-1.1	3.5	-2.0	3.5
Arm fat percentage (right)	0.6	2.2	5.6	-1.6	0.9	1.2	1.1	1.8	-0.4	-0.3	2.4	2.2
Trunk fat-free mass	1.4	8.2	27.1	-0.1	2.4	-3.8	1.3	-5.2	0.4	-1.9	1.4	-4.4
Hip circumference	0.8	3.6	7.6	-0.5	2.0	-2.0	1.8	-2.4	0.6	-2.8	2.6	-0.3
Time employed in main current job	0.8	1.0	5.4	-0.1	2.3	0.9	-1.2	0.7	-0.4	0.1	-0.2	-0.6
Alcohol intake versus 10 years previously	0.6	0.9	4.9	-0.6	-0.7	-0.3	2.2	-0.1	1.1	-0.0	-0.1	1.1
Father’s age at death	1.1	1.4	4.8	-2.2	-1.4	-0.3	1.8	0.2	-0.7	-0.8	0.6	1.2
Worrier / anxious feelings	1.2	2.2	10.0	0.6	-0.3	-0.9	-0.9	-1.3	1.5	-3.2	2.0	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.2	-0.6	-1.4	-0.3	0.7	-0.0	0.2	-1.5	0.4	1.1
Falls in the last year	0.8	1.1	5.0	-1.2	2.2	0.1	0.2	1.0	-0.6	-1.1	0.6	0.8
Hair/balding pattern: Pattern 3	0.6	0.9	2.7	-1.7	-1.5	0.8	0.9	-0.1	-1.1	-0.5	-0.1	-0.1
Number of live births	1.4	2.0	4.7	1.6	0.1	-1.3	1.5	-0.2	1.8	2.2	-1.5	0.8
Forced expiratory volume in 1-second (FEV1)	1.5	5.2	14.7	1.4	-1.9	-2.4	0.1	-3.5	1.3	1.1	-2.3	-3.8
Pulse rate	1.7	2.9	11.8	-0.7	0.2	0.2	2.4	1.7	1.4	-1.1	1.5	3.4
Happiness	2.6	3.2	10.2	-2.4	-0.5	2.0	-1.7	-0.5	-3.2	-1.1	1.5	-1.4
Noisy workplace	0.9	1.1	3.9	0.4	1.8	-0.6	0.3	-1.4	-0.0	2.0	-0.3	-0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.2	6.4	-0.2	-2.5	-0.3	-0.8	0.4	-0.5	-1.6	0.2	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.5	0.3	-0.3	-0.4	-0.3	-1.2	0.1	1.0	0.3	-0.4
Mouth/teeth dental problems: Dentures	2.2	3.6	11.4	-2.3	-0.5	3.1	0.1	1.7	-3.4	0.9	0.7	-1.4
Asthma	0.4	0.8	4.3	-0.7	1.3	-0.2	0.2	0.5	0.1	-0.1	0.4	2.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	5.6	-0.7	1.0	-0.9	0.4	-1.8	-0.3	-0.8	0.6	-2.4
Medication: Cholesterol lowering	0.9	1.5	4.2	-1.4	-1.9	0.6	-0.1	0.3	-1.2	-2.0	1.1	0.7
Depression (self-reported)	0.5	0.6	1.5	0.9	0.6	-0.8	-1.1	0.1	0.4	-1.2	1.0	0.4
Medication: Lansoprazole	0.6	0.7	1.9	-0.2	1.2	1.3	0.7	0.3	-0.2	1.4	-0.4	-0.5
Prospective memory result	0.5	0.6	1.6	0.9	0.6	-1.0	0.8	0.1	0.7	0.0	-1.3	-0.0
Lung cancer (father)	0.8	0.9	2.7	0.2	-0.0	-1.0	0.6	-1.7	0.8	-1.5	0.8	-0.9
Illnesses of mother	0.3	0.4	1.1	-0.0	0.3	1.0	-0.6	0.0	-1.0	0.0	-1.0	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	16.0	0.0	-1.4	-1.1	0.6	-3.3	0.4	1.0	-1.3	-4.0
Pulse wave Arterial Stiffness index	0.6	0.7	2.2	-0.2	0.3	0.9	1.2	0.7	0.8	0.4	0.3	1.5
Impedance of arm (left)	1.8	8.3	32.6	-0.6	-1.1	3.8	-1.2	5.7	-1.5	3.3	-2.3	2.4
Arm fat mass (right)	0.3	1.4	5.6	-1.2	1.1	-0.2	1.6	0.1	-0.1	-0.8	2.4	0.7
Trunk predicted mass	1.4	8.1	26.6	-0.0	2.4	-3.8	1.3	-5.2	0.4	-1.9	1.3	-4.3
Standing height	0.4	4.2	22.6	-0.8	0.4	-1.6	-0.3	-2.6	-1.7	0.9	-1.2	-4.8
Length of working week for main job	0.2	0.2	1.3	0.8	-0.1	-0.1	-1.1	0.5	-0.1	0.1	0.1	0.1
Exposure to tobacco smoke at home	0.7	0.7	3.1	0.1	0.7	0.6	-1.1	1.8	-0.2	-0.6	-0.4	1.1
Breastfed as a baby	0.7	0.9	3.9	-0.1	-1.2	-0.2	-0.3	0.1	-0.8	0.8	-0.9	-2.0
Tense / ‘highly strung’	0.6	1.0	2.2	1.0	0.9	-0.4	-1.0	0.7	1.5	0.0	-0.8	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	7.3	0.3	2.7	1.6	-1.4	1.1	0.2	0.1	1.3	1.2
Hair/balding pattern: Pattern 4	0.7	1.7	3.3	1.1	-1.2	-1.8	0.6	-1.6	0.7	-0.4	-1.8	-1.6
Birth weight of first child	0.7	1.2	5.9	-0.0	-2.4	0.4	-1.1	-0.7	-0.6	-0.4	0.0	-1.6
Peak expiratory flow (PEF)	0.4	1.0	4.6	-0.0	-1.3	-0.3	0.2	-0.8	0.3	0.8	-1.2	-2.1
Pulse wave reflection index	1.4	1.8	5.5	0.7	-1.1	1.5	-1.2	2.4	0.2	1.5	-1.3	1.0
Ever highly irritable/argumentative for 2 days	0.5	0.5	1.9	0.8	1.4	-0.9	-0.2	-0.6	0.5	0.2	-1.0	0.1
Loud music exposure frequency	0.3	0.3	1.0	0.0	0.3	-0.0	0.9	0.5	0.4	1.0	-0.2	0.6
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	5.6	-0.3	-2.4	0.2	0.0	-0.9	0.1	-1.4	0.1	-0.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.6	0.8	-0.7	-0.3	0.1	0.4	1.2	-0.5	0.1	1.6
Blood clot in the leg (DVT)	0.5	0.7	3.6	-0.4	1.9	-1.2	0.7	0.7	-0.3	0.1	-0.1	-0.1
Medication: Paracetamol	0.7	1.2	2.4	1.3	1.6	0.5	-0.5	1.1	1.4	1.2	-1.1	0.3
Headache pain in last month	0.4	0.6	1.3	-0.2	-0.6	-1.1	-0.3	-1.0	-0.4	-0.7	-1.1	-0.9
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.5	0.3	0.7	-0.0	1.1	0.1	0.9	1.2	-0.3	0.5
Glaucoma (self-reported)	1.5	1.8	4.8	1.5	0.2	-2.0	0.4	1.2	1.7	0.1	-2.2	0.6
Gout (self-reported)	1.4	1.9	5.0	2.2	-0.6	-1.2	-0.3	0.2	2.1	-0.2	-2.0	1.3
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	4.4	-0.4	0.3	0.0	0.4	-1.3	-0.1	-1.1	2.1	-0.9
Medication: Amlodipine	1.7	2.4	5.4	-1.4	1.6	1.5	-0.3	-1.1	-2.3	1.3	2.0	-1.3
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.5	0.1	0.5	-0.2	1.1	-0.3	0.9	-0.0	0.3	1.2
Birth weight	0.5	1.0	6.0	0.4	-0.1	-0.0	0.6	1.1	0.4	0.7	-2.5	-0.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.4	-0.7	-0.1	-0.7	-0.1	-1.3	-0.8	-1.1	1.6	-0.1
High blood pressure (siblings)	0.9	1.2	3.6	1.0	0.4	-1.2	1.1	0.3	1.9	-1.5	-0.6	1.0
Forced vital capacity (FVC), Best measure	1.1	4.0	15.3	0.2	-1.3	-1.5	0.8	-3.6	0.6	1.0	-1.2	-3.9
Body fat percentage	0.5	1.8	3.5	-1.9	0.1	1.4	0.7	1.8	-1.0	0.1	1.9	1.6
Leg fat percentage (right)	0.5	1.7	6.2	-1.8	0.7	1.1	0.5	0.7	-0.9	-0.3	2.5	1.5
Arm fat-free mass (right)	1.4	7.2	25.8	-0.2	1.6	-3.5	1.8	-5.1	0.4	-1.9	1.4	-3.9
Exposure to tobacco smoke outside home	0.5	0.7	1.8	-0.5	-1.3	0.4	-0.9	0.3	-0.8	-0.8	0.7	1.2
Comparative body size at age 10	0.5	1.4	5.7	-0.7	-1.3	-1.5	2.4	-1.1	0.5	-1.1	-0.1	-0.3
Number of full brothers	0.4	0.5	1.3	-1.0	-0.7	-0.1	0.0	0.1	-0.5	-1.1	0.9	0.6
Worry too long after embarrassment	0.8	1.3	5.6	0.8	-2.4	0.8	-1.1	-1.5	0.5	-0.3	0.3	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	4.3	-0.9	0.3	1.8	0.9	2.1	-0.5	0.7	0.4	1.7
Wheeze or whistling in the chest in last year	0.6	1.1	3.5	-1.9	0.7	0.2	0.8	-0.4	-0.7	-1.2	1.6	0.9
Number of children fathered	0.3	0.3	0.6	-0.1	-0.6	-0.6	-0.8	0.3	-0.8	-0.7	-0.5	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.8	1.4	0.7	-0.9	-1.7	0.3	0.8	0.3	-0.8	-0.8
Age at first live birth	1.4	2.6	9.3	-2.1	-3.0	1.0	0.7	-0.6	-1.5	-1.7	1.3	-0.6
Pulse wave peak to peak time	0.7	0.8	3.0	0.2	-0.2	-1.0	-1.2	-0.8	-0.9	-0.5	-0.5	-1.7
Health satisfaction	0.5	0.6	1.4	-0.8	-0.9	0.3	-0.2	-0.8	-1.2	-0.6	0.9	0.8
Shortness of breath walking on level ground	0.8	0.9	2.2	0.5	0.5	-1.2	0.6	-0.6	1.0	-0.9	-1.5	1.2
Qualifications: College or University degree	0.7	2.2	15.0	-0.5	-3.9	0.2	-1.2	0.9	-1.2	0.5	0.7	0.3
Eye problems/disorders: None of the above	0.8	0.9	2.0	-1.3	-1.4	0.2	0.3	-0.8	-1.0	-0.6	1.3	-0.7
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.6	-1.3	-1.2	0.6	1.1	-0.4	-0.9	0.2	-0.2	-1.2
Emphysema/chronic bronchitis	2.0	2.3	7.0	-2.0	1.1	-0.2	0.7	-0.7	-1.4	-2.6	2.3	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	2.6	0.6	-1.6	-1.3	-0.1	-1.4	0.2	-0.2	0.1	0.9
Neck or shoulder pain in last month	1.9	2.8	10.4	0.4	3.2	-2.2	0.1	-2.2	1.0	-1.5	1.0	-0.6
Medication: Blood pressure	0.3	0.5	1.1	0.2	0.6	-1.0	-0.8	-0.6	-0.1	-1.1	0.8	-0.9
Angina (self-reported)	0.6	0.7	2.1	0.1	-1.0	1.4	-1.0	-0.3	-0.0	-0.4	-0.8	-1.3
Migraine (self-reported)	0.4	0.5	2.0	0.5	0.7	-0.6	-0.5	-1.4	0.1	0.9	0.2	-0.6
Medication: Ibuprofen	0.9	1.1	4.3	-0.4	1.1	-1.0	-0.3	-1.5	-0.4	-0.7	0.3	-2.1
Medication: Allopurinol	0.7	0.9	1.8	1.0	-0.8	-0.6	0.1	0.5	1.2	-1.2	-1.3	1.1
Medication: Omeprazole	2.1	2.5	6.0	-0.2	1.9	-0.1	2.2	0.8	1.6	-1.1	1.8	2.5
Medication: Seretide 50 evohaler	0.5	0.6	2.9	0.4	1.7	-0.6	0.3	0.8	0.6	0.0	-0.5	0.8
Mean time to correctly identify matches	0.8	1.5	8.1	0.8	2.8	0.3	1.1	0.9	1.0	-0.1	-0.5	1.3
Heart disease (mother)	2.7	3.3	6.7	-2.6	-2.3	0.7	1.4	-2.3	-1.9	-0.9	1.8	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	5.7	1.2	0.5	0.8	-0.5	1.6	-0.2	2.2	-2.4	-0.6
Whole body fat mass	0.2	1.0	4.2	-1.5	0.6	0.2	1.2	0.3	-0.6	-0.4	2.1	0.4
Leg fat mass (right)	0.3	1.2	6.0	-1.2	0.9	-0.4	1.1	-0.4	-0.3	-0.8	2.5	0.5
Arm predicted mass (right)	1.4	7.2	25.6	-0.2	1.5	-3.4	1.4	-5.1	0.2	-1.6	1.4	-4.3
Pulse rate, automated reading	3.0	9.7	35.6	0.1	0.2	-2.5	3.3	1.7	4.2	-2.6	2.7	6.0
Alcohol intake frequency.	0.6	1.5	4.0	-1.5	-1.4	0.2	2.0	-0.4	-0.4	-1.2	0.3	1.7
Comparative height size at age 10	1.1	5.9	10.7	2.3	2.9	-2.7	0.9	-2.9	1.5	1.8	-2.6	-3.3
Number of full sisters	1.6	2.0	6.6	1.9	1.3	-1.9	0.9	-0.1	2.6	-0.1	-0.8	1.1
Suffer from ‘nerves’	0.3	0.5	1.3	0.5	0.9	0.4	0.3	-1.0	1.1	-0.3	0.6	0.1
Overall health rating	0.6	1.3	5.0	-1.0	0.1	-0.5	0.9	0.6	-0.4	-2.2	1.3	1.6
Chest pain or discomfort	0.9	1.3	2.6	-0.8	1.5	1.6	-0.1	1.6	-0.3	-0.6	1.2	1.3
Had major operations	0.8	1.0	4.8	-0.6	2.2	-0.5	1.1	-0.4	0.2	-0.9	0.9	0.8
Age at last live birth	0.7	1.1	5.6	-1.0	-2.4	1.1	1.0	0.5	-0.7	0.3	0.3	-0.3
Family relationship satisfaction	1.1	1.3	3.3	-0.6	1.3	1.2	-1.0	-1.4	-1.8	0.4	1.1	-0.8
Leg pain on walking	0.6	0.7	2.4	-0.6	0.7	-0.9	0.1	0.1	-0.9	-1.6	0.7	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.7	0.0	1.4	1.3	1.1	0.3	-0.0	1.9	-0.5	-0.3
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.0	0.6	0.7	0.8	-0.0	1.5	0.7	1.7	-0.4	0.7
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	2.2	1.3	-1.5	0.3	0.2	0.7	1.2	0.9	-0.3	-0.3
Medication: Aspirin	1.5	2.0	5.3	-1.4	0.3	2.3	-0.3	2.3	-1.8	1.3	-0.0	0.4
Supplements: Vitamin C	1.2	1.4	7.4	-0.1	-2.7	-0.6	-1.2	-0.9	-0.5	-0.9	0.1	-1.3
Knee pain experienced in last month	0.9	1.4	4.7	0.2	1.6	-1.4	1.6	-2.2	0.3	-1.0	0.1	0.1
Hypertension (Self-reported)	0.2	0.6	2.6	-0.1	1.6	-0.1	0.1	-0.4	-0.1	-0.3	1.6	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.5	1.2	1.2	0.6	0.5	1.6	1.9	1.2	-0.4	1.1
Illnesses of father: Heart disease	0.8	1.0	5.2	0.5	-0.0	1.4	-1.0	-0.7	0.3	0.7	0.0	-2.3
Illnesses of siblings: Diabetes	3.4	4.2	8.7	1.8	-1.3	0.9	1.4	2.4	2.3	2.5	-2.0	3.0
Smoking status: Previous	1.0	1.5	3.8	-1.4	-0.9	1.9	1.3	-0.5	-1.4	0.8	1.0	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	6.5	0.8	0.6	-1.7	-0.6	-2.1	0.4	0.5	-1.3	-2.6
Whole body fat-free mass	1.1	6.4	19.7	-0.1	2.2	-3.5	1.5	-4.4	0.4	-1.7	1.3	-3.8
Leg fat-free mass (right)	0.7	4.0	9.7	0.4	1.7	-3.0	1.5	-3.1	0.9	-1.3	0.6	-3.0
Arm fat percentage (left)	0.5	1.8	5.2	-1.6	0.7	1.1	1.3	1.6	-0.5	-0.3	2.3	1.7
Average weekly red wine intake	0.4	0.6	2.6	1.1	-0.2	-0.7	-1.6	0.3	0.2	0.7	-0.2	0.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.3	1.2	1.5	-0.3	-0.1	-0.4	1.4	-0.6	-0.1	0.4
Mood swings	1.1	2.1	5.9	-1.7	1.2	2.4	-1.0	1.6	-2.1	-0.3	0.6	-0.3
Loneliness, isolation	1.1	1.5	3.2	-1.4	-0.5	1.7	-0.8	-0.9	-1.8	-0.5	1.7	-0.5
Long-standing illness, disability or infirmity	0.8	1.3	4.8	-1.5	0.5	-0.4	1.4	0.6	-0.3	-2.2	0.4	1.2
Ever had bowel cancer screening	1.6	1.9	8.4	0.3	1.6	0.3	1.1	2.9	0.7	0.3	-1.6	1.3
Diabetes diagnosed by doctor	0.6	0.9	2.8	-1.2	-1.0	0.9	-0.0	1.7	-0.9	-0.2	0.7	1.1
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	7.3	-1.7	-0.8	2.7	-0.8	1.5	-2.3	0.7	0.3	-0.0
Friendships satisfaction	1.4	1.8	4.8	-1.3	0.3	1.2	-1.0	-1.5	-2.1	-0.0	-0.1	-2.2
Qualifications: nursing, teaching	1.1	1.7	3.7	-1.9	-1.9	-0.4	0.4	-0.2	-1.7	-1.8	1.1	0.5
Commuting to job workplace: Walk	0.6	0.6	2.2	0.1	-0.8	1.0	-1.5	0.4	-0.9	0.4	-0.1	0.9
Eye problems/disorders: Cataract	0.9	1.0	4.7	0.5	2.2	0.2	-0.4	0.5	-0.3	1.3	-1.4	0.1
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	5.9	1.5	2.2	-1.1	0.8	0.6	2.4	0.3	-1.1	1.6
Medication for cholesterol	0.5	0.7	2.0	0.2	-0.2	-1.1	1.4	-0.4	1.1	-0.5	-1.0	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	4.0	0.9	-0.9	-0.0	1.1	0.3	0.5	1.0	-2.0	-0.4
Back pain experienced in last month	3.8	5.5	24.2	-0.3	0.8	-2.6	1.6	-4.9	0.8	-2.6	2.5	-1.3
Mineral and other dietary supplements	1.0	1.3	4.9	0.5	-1.2	0.5	-0.1	0.7	1.2	-0.1	1.8	2.2
Breast cancer (self-reported)	0.5	0.7	2.3	-0.5	0.1	-0.3	1.1	0.3	0.4	-0.8	1.1	1.5
Asthma (self-reported)	0.4	0.8	4.8	-0.6	1.1	-0.3	0.4	0.3	0.4	0.1	0.4	2.2
Osteoporosis (self-reported)	1.9	2.3	5.1	-0.8	-0.5	2.0	1.8	2.2	-0.8	2.2	-1.4	0.8
Osteoarthritis (self-reported)	0.8	1.1	3.1	0.9	1.8	1.0	0.5	0.5	0.2	0.8	-1.7	-0.7
Medication: Aspirin	1.5	1.9	5.5	-1.3	-0.2	2.3	-1.0	2.1	-2.0	0.8	0.2	0.1
Medication: Gliclazide	2.1	2.3	11.4	-0.8	0.7	1.6	0.7	3.4	-0.2	0.1	-1.9	1.4
Illnesses of father: None of the above (group 1)	0.1	0.2	0.7	0.5	0.1	-0.8	-0.2	-0.1	-0.3	-0.3	-0.0	0.5
Smoking status: Current	0.9	1.5	5.6	-0.5	1.1	1.4	-1.0	2.4	-1.3	1.0	0.3	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	8.6	-0.2	-1.2	0.5	0.0	-1.5	0.0	0.9	-0.9	-2.9
Whole body water mass	1.2	6.8	20.7	-0.0	2.2	-3.6	1.5	-4.5	0.5	-1.8	1.2	-3.9
Leg predicted mass (right)	0.7	4.0	9.5	0.4	1.7	-3.1	1.4	-3.1	0.9	-1.4	0.6	-2.9
Arm fat mass (left)	0.2	1.0	4.1	-0.7	1.3	-0.6	1.4	-0.1	0.3	-0.7	2.0	0.3
Number of self-reported non-cancer illnesses	0.4	0.7	2.2	-1.1	0.5	-0.0	0.8	0.0	-0.8	-0.9	1.5	0.8
Average weekly champagne plus white wine intake	0.5	0.6	1.9	-0.3	-1.4	-0.8	-0.6	-0.8	-0.9	-0.6	0.5	-0.9
Miserableness	0.8	1.4	3.1	-1.6	-0.6	1.7	-0.9	-0.2	-1.8	-1.1	1.0	-0.9
Guilty feelings	0.8	1.2	2.7	-1.4	-0.6	1.6	-0.5	-0.3	-1.3	-1.3	1.3	-0.5
Wears glasses or contact lenses	0.6	0.7	2.2	-0.8	1.2	-1.1	0.4	0.1	-0.6	-1.5	0.4	-0.2
Ever taken oral contraceptive pill	0.7	0.8	4.2	-0.4	-0.6	0.2	-2.0	-0.0	-1.1	1.0	0.2	-0.4
Hearing aid user	0.7	0.8	4.1	0.1	-0.3	-0.2	0.1	2.0	0.8	-0.4	0.3	1.5
Mother’s age at death	1.6	2.0	5.7	-2.3	0.4	0.4	1.7	-0.7	-2.4	0.1	1.6	-0.5
Financial situation satisfaction	0.3	0.4	2.1	-0.3	1.4	-0.0	-0.1	0.2	-0.1	-0.7	0.8	0.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.1	0.5	-1.0	-0.0	0.7	1.1	0.7	0.8	-1.1	1.5
Commuting to job workplace: Public transport	2.0	2.3	7.5	-1.7	-2.7	-0.2	1.2	-1.6	-1.1	-1.8	1.5	-0.2
Eye problems/disorders: Glaucoma	1.8	2.2	6.1	1.2	0.7	-2.5	1.0	1.4	1.6	0.7	-2.0	1.4
Medication: Blood pressure	0.2	0.3	1.0	0.3	1.0	0.7	-0.3	0.9	-0.3	0.2	0.4	0.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.6	-0.5	1.3	-0.7	0.0	-0.4	-0.7	-0.9	-0.1	-0.0
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.6	-0.5	1.1	-0.3	0.4	0.3	-0.7	0.3	-1.6	-1.1
High cholesterol (Self-reported)	1.5	2.7	8.5	-2.0	-1.0	2.9	-0.7	0.3	-2.6	-0.2	1.7	-0.6
Medication: Bendroflumethiazide	0.1	0.2	0.4	0.1	0.2	-0.5	-0.3	0.7	-0.3	-0.5	0.0	-0.6
Medication: Paracetamol	0.4	0.7	2.9	0.5	1.7	0.3	-0.6	0.7	0.5	0.5	-1.2	-0.3
Medication: Lisinopril	1.2	1.5	3.1	0.2	1.1	-1.6	0.5	1.7	1.3	-1.0	-1.0	1.8
Medication: Atorvastatin	0.8	1.0	3.3	-1.1	0.1	1.8	-0.6	0.3	-1.1	-0.1	0.7	-1.4
Illnesses of father: High blood pressure	0.2	0.3	1.7	-0.3	0.6	0.4	-0.2	0.0	-0.4	-0.0	0.1	-1.3
Alcohol drinker status: Never	0.9	1.0	2.3	0.4	0.5	-1.2	1.1	-0.1	1.4	-1.5	-0.7	1.1
Ever smoked	0.1	0.2	1.0	-0.1	-0.2	-0.7	1.0	-0.4	0.2	0.1	0.4	-0.2
Basal metabolic rate	1.0	5.5	16.3	-0.1	2.0	-3.3	1.5	-4.0	0.5	-1.6	1.4	-3.3
Leg fat percentage (left)	0.3	0.9	3.7	-1.4	0.3	0.4	0.7	0.1	-0.3	-0.8	1.9	1.0
Arm fat-free mass (left)	1.3	6.4	22.6	-0.1	1.9	-3.3	1.2	-4.8	0.4	-1.7	1.6	-3.6
Number of operations (self-reported)	1.5	2.2	7.0	-0.9	2.6	0.0	1.7	2.6	0.2	-0.5	-0.0	1.5
Average weekly beer plus cider intake	0.5	0.7	1.8	-1.1	-0.2	0.1	1.0	-0.3	-0.3	-1.1	0.9	1.4
Irritability	0.9	1.5	4.3	-1.5	-0.3	0.6	-0.1	0.0	-1.0	-2.1	2.0	1.5
Risk taking	0.8	1.1	2.4	-1.0	0.7	1.6	1.2	-0.0	-0.9	1.3	1.4	0.7
Ever had prostate specific antigen (PSA) test	0.8	0.9	5.8	0.3	0.3	-0.5	-1.2	-0.4	-0.1	-2.4	0.4	-0.3
Fractured/broken bones in last 5 years	4.8	6.1	24.1	-1.9	-0.4	3.4	-0.2	4.9	-2.2	1.7	-0.9	2.7
Age started oral contraceptive pill	0.4	0.6	2.1	-1.4	0.2	0.4	1.4	0.4	-0.5	-0.1	0.5	0.2
Diastolic blood pressure, automated reading	0.6	1.8	4.2	1.5	1.8	-0.1	-0.0	0.8	2.0	1.7	-0.1	1.8
Ever depressed for a whole week	1.7	2.1	8.4	-0.5	1.1	-0.4	0.3	-2.8	-0.4	-0.8	2.9	0.3
Unable to work because of sickness or disability	1.6	2.1	8.1	-0.2	1.4	-0.3	0.8	2.7	0.8	-0.2	-0.3	2.8
Commuting to job workplace: Cycle	1.7	2.0	4.9	-1.2	-2.2	0.8	-0.5	-2.0	-1.6	-0.7	1.2	-1.5
Myopia	1.1	1.6	6.9	-1.2	0.1	1.6	0.7	2.6	-1.0	0.1	0.8	1.3
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.9	0.0	-1.0	-0.1	0.2	0.4	0.0	0.4	-0.7	0.1
Cholesterol lowering medication	1.8	2.6	9.2	-1.9	-0.0	3.0	-0.8	0.3	-2.2	0.5	1.0	-2.0
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.3	0.1	1.1	-0.2	1.5	0.6	1.6	-1.0	0.9	2.1
Pain experienced in last month	1.2	2.0	8.1	-0.2	-1.6	2.1	-1.0	2.9	-0.4	0.9	0.1	1.2
Supplements: Calcium	3.4	3.7	9.0	-2.1	-0.4	3.0	0.9	2.3	-2.8	2.2	-0.5	0.8
Basal cell carcinoma (self-reported)	0.9	1.1	5.3	-0.9	0.1	2.3	0.8	1.3	-0.3	0.4	0.1	0.8
Heart attack/myocardial infarction (self-reported)	2.5	3.2	10.6	-1.5	-1.7	3.3	-1.6	2.1	-2.4	0.5	0.2	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	4.4	-0.2	2.1	-1.2	0.2	0.9	-0.2	0.0	-0.0	-0.0
Heart disease (siblings)	0.3	0.3	1.2	0.5	0.7	0.1	0.3	0.3	0.1	1.1	-0.7	0.6
Alcohol drinker status: Previous	0.4	0.5	2.0	-0.5	-0.6	0.3	0.7	0.8	-0.2	-0.6	-1.4	0.3
Pack years of smoking	0.7	1.1	2.8	-1.3	1.0	1.2	0.4	1.7	-1.3	0.1	0.7	0.4
Impedance of whole body	1.4	7.2	21.1	-0.7	-2.0	3.5	-2.2	4.6	-1.8	3.0	-2.4	2.1
Leg fat mass (left)	0.3	1.2	5.2	-1.0	0.8	-0.9	1.2	-0.8	0.0	-1.1	2.3	0.2
Arm predicted mass (left)	1.3	6.4	22.9	-0.3	1.9	-3.4	1.6	-4.8	0.4	-1.8	1.5	-3.5