TWAS hub - LOC100130872

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.171	0.0400	2.5e-14	0.156	0.143	0.164	0.156	0.152	1.4e-18	4.9e-17	1.8e-19	1.4e-18	4.2e-18
2	TCGA	Colon Adenocarcinoma	0.073	0.0460	8.4e-03	-0.003	0.005	-0.003	NA	0.000	5.7e-01	1.6e-01	5.0e-01	NA	3.4e-01
3	TCGA	Prostate Adenocarcinoma	0.075	0.0388	5.2e-04	0.028	0.037	0.021	NA	0.031	6.1e-04	8.9e-05	2.5e-03	NA	2.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate, automated reading	7.3	23.5	38.6	1.9	5.3	6.2
Heel T-Score	6.9	54.9	125.4	11.2	-3.4	-5.2
Fractured/broken bones in last 5 years	6.2	8.0	20.4	-4.5	1.7	0.9
Diabetes (father)	5.8	7.2	10.1	1.5	3.2	3.1
Heel bone mineral density (BMD) T-score, automated (right)	5.5	12.5	22.7	4.8	-2.4	-3.0
Chronotype (morning person)	5.2	12.1	15.4	3.3	3.9	3.2
Heart attack	5.2	6.6	9.3	-3.0	-2.3	-2.3
Heart attack/myocardial infarction (self-reported)	4.8	6.2	7.8	-2.8	-2.5	-2.2
Heel bone mineral density (BMD) T-score, automated (left)	4.4	10.1	23.5	4.8	-1.5	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	4.2	4.5	8.4	-2.9	-1.4	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	4.0	5.3	6.2	-2.1	-2.3	-2.5
Happiness	4.0	4.9	7.2	-1.9	-1.9	-2.7
Smoking Status	3.9	9.4	19.4	-4.4	-2.2	-2.0
Illnesses of siblings: Diabetes	3.6	4.4	7.9	0.8	2.2	2.8
Unable to work because of sickness or disability	3.5	4.5	7.4	-1.2	2.2	2.7
Supplements: Calcium	3.4	3.7	10.7	-3.3	0.5	-0.5
Primary Biliary Cirrhosis	3.3	4.7	5.5	2.4	1.9	2.2
Mouth/teeth dental problems: Dentures	3.2	5.4	10.8	-3.3	-1.6	-1.7
Breast Cancer	3.1	7.5	14.1	0.4	-2.9	-3.8
Alcohol drinker status: Never	3.1	3.7	4.8	1.9	2.2	1.6
Cholesterol lowering medication	3.1	4.5	6.0	-1.4	-2.5	-2.3
Medication: Omeprazole (e.g. Zanprol)	3.1	3.8	5.2	1.1	2.2	2.3
Ever had hysterectomy (womb removed)	3.0	3.4	8.7	-2.9	-0.1	1.3
Medication: Aspirin	2.9	3.8	5.1	-2.1	-2.3	-1.3
Bilateral oophorectomy (both ovaries removed)	2.8	3.2	6.5	-2.5	-1.5	-0.9
Depressed Affect (Nagel 2018)	2.7	5.6	6.5	-2.6	-2.3	-2.3
Mean Putamen Volume	2.7	3.1	4.4	-1.1	-2.1	-1.9
Alcohol usually taken with meals	2.7	4.3	5.8	-1.2	-2.4	-2.4
Pulse rate	2.7	4.5	7.9	0.2	2.4	2.8
Number of full sisters	2.6	3.1	5.2	0.9	2.3	1.8
Medication: Aspirin	2.6	3.4	5.7	-2.4	-1.9	-0.9
Heart disease (mother)	2.5	3.0	6.0	-0.1	-2.5	-1.7
Number of live births	2.4	3.5	4.0	1.6	2.0	2.0
Medication: Omeprazole	2.4	2.8	4.3	0.6	1.9	2.1
Coronary Artery Disease (CAD)	2.3	2.7	3.5	1.6	1.4	1.9
LDL Cholesterol	2.3	3.6	8.4	-0.6	-1.5	-2.9
Rheumatoid Arthritis	2.3	3.1	5.2	-0.1	2.0	2.3
Ever had bowel cancer screening	2.3	2.7	4.5	-1.5	1.2	2.1
HbA1C	2.1	2.4	6.9	2.6	-0.5	0.2
Smoking status: Previous	2.1	3.2	4.1	-1.6	-1.7	-2.0
Bipolar Disorder or Schizophrenia	2.0	4.8	9.7	3.1	0.8	2.0
Maternal smoking around birth	2.0	2.9	6.1	-2.5	-0.8	-1.5
Pain all over the body in last month	2.0	2.2	4.6	-2.2	1.0	1.0
Mood swings	2.0	3.6	8.4	-2.9	-1.1	-1.0
Mouth/teeth dental problems: Mouth ulcers	2.0	3.2	5.2	1.3	1.6	2.3
High cholesterol (Self-reported)	2.0	3.5	4.6	-2.1	-1.5	-1.9
Commuting to job workplace: Cycle	2.0	2.4	4.0	0.9	-1.6	-2.0
Prostate Cancer	1.9	2.6	4.1	-2.0	-1.8	-0.7
Fed-up feelings	1.9	3.4	4.8	-2.2	-2.0	-1.2
Angina (self-reported)	1.9	2.5	5.6	0.7	-2.4	-1.1
Friendships satisfaction	1.9	2.4	5.9	-0.3	-1.0	-2.4
Hand grip strength (right)	1.8	4.8	6.9	0.9	-2.6	-2.6
Medication: Simvastatin	1.8	2.6	6.8	-2.6	-0.5	-0.9
Medication: Gliclazide	1.8	2.0	3.7	-1.9	0.6	1.4
Miserableness	1.8	3.1	3.9	-1.3	-2.0	-1.9
Depression (Nagel 2018)	1.7	2.5	3.7	-1.9	-1.3	-1.5
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	4.0	-2.0	-0.4	-1.2
Angina	1.7	2.3	4.9	0.7	-2.2	-1.2
Medication: Metformin	1.7	2.4	5.0	0.6	1.3	2.2
Current tobacco smoking	1.7	2.8	8.3	-2.9	-0.1	-0.2
Past tobacco smoking	1.7	3.0	3.6	1.9	1.8	1.5
Nervous feelings	1.7	3.1	5.2	2.3	1.2	1.6
Illnesses of father: Heart disease	1.7	2.3	5.0	0.8	-2.2	-1.1
Breast cancer (self-reported)	1.7	2.0	3.2	-0.8	1.8	1.5
Osteoporosis (self-reported)	1.7	2.0	4.3	-2.1	0.9	1.0
Eye problems/disorders: Glaucoma	1.7	2.0	4.5	-0.2	1.2	2.1
Ever used hormone-replacement therapy (HRT)	1.6	2.1	4.4	-1.0	-2.1	-0.9
Had other major operations	1.6	2.0	3.4	-1.8	-1.4	-0.7
High blood pressure (siblings)	1.6	2.3	4.5	0.9	1.3	2.1
Smoking status: Current	1.6	2.5	7.4	-2.7	-0.1	0.0
Number of operations (self-reported)	1.6	2.4	5.0	-2.2	-0.4	1.4
Schizophrenia (2014)	1.5	3.2	7.2	2.7	0.7	1.4
Waist Hip Ratio (WHR)	1.5	6.5	8.5	-2.9	-2.7	-2.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	6.2	2.4	-2.5	-1.5
Medication: Amlodipine	1.5	2.1	3.5	-1.2	-1.2	-1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	5.8	1.5	-2.4	-1.1
Bipolar Disorder (2018)	1.4	2.2	5.2	2.3	0.9	0.8
Schizophrenia (2018)	1.4	2.9	4.7	2.2	0.3	2.0
Bipolar Disorder (2011)	1.4	1.4	2.8	0.0	1.2	1.7
Medication: Atenolol	1.4	1.7	4.0	-0.6	-2.0	-0.9
Illnesses of siblings	1.4	1.9	3.8	-0.3	-1.4	-2.0
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	10.1	3.2	-1.7	-1.1
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	2.4	1.1	1.3	1.6
Gout (self-reported)	1.4	1.9	2.9	1.7	0.5	1.6
Mineral and other dietary supplements	1.4	1.8	2.1	1.3	1.3	1.4
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	4.5	-2.1	0.2	0.4
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	2.8	-1.6	-1.7	-0.8
Hair/balding pattern: Pattern 2	1.3	1.6	4.2	2.0	-0.7	-0.4
Fluid intelligence score	1.3	2.8	4.7	1.9	0.3	2.2
Tense / ‘highly strung’	1.3	2.2	3.5	0.3	1.7	1.9
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	3.6	0.9	1.9	1.4
Glaucoma (self-reported)	1.3	1.6	4.0	0.2	0.8	2.0
Mother’s age at death	1.3	1.6	2.3	-1.0	-1.2	-1.5
Myopia	1.3	1.8	4.4	-2.1	0.7	0.8
Lupus	1.2	1.9	4.3	0.9	0.6	2.1
Hand grip strength (left)	1.2	3.1	5.2	0.1	-2.1	-2.3
Impedance of arm (right)	1.2	5.8	9.5	-3.1	2.1	1.9
Medication: Ventolin 100micrograms inhaler	1.2	1.5	2.0	1.3	1.4	0.9
Forced vital capacity (FVC), Best measure	1.2	4.5	5.8	2.3	-2.4	-1.5
Shortness of breath walking on level ground	1.2	1.4	1.7	1.2	1.3	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.0	0.6	1.0	1.7
Guilty feelings	1.2	1.7	2.6	-1.2	-1.6	-1.1
Crohns Disease (2012)	1.1	1.8	2.4	1.0	1.4	1.5
Fasting Glucose	1.1	1.3	2.2	1.5	0.9	1.0
Respiratory disease	1.1	2.5	6.7	0.1	2.6	1.0
Medication: Ramipril	1.1	1.4	2.3	-1.1	-0.8	-1.5
Breastfed as a baby	1.1	1.3	2.9	0.2	-1.7	-1.0
Ever taken oral contraceptive pill	1.1	1.2	2.0	-0.8	-1.0	-1.4
Hearing aid user	1.1	1.2	2.4	-1.1	0.3	1.5
Medication: Atorvastatin	1.1	1.3	3.2	0.0	-1.8	-0.8
Worry (Nagel 2018)	1.0	2.2	6.3	2.5	-0.2	0.5
Mouth/teeth dental problems	1.0	1.6	4.3	2.1	0.6	0.2
Father’s age at death	1.0	1.4	3.5	-0.5	1.9	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.2	-1.5	1.0	0.9
Back pain experienced in last month	1.0	1.5	4.0	2.0	0.4	-0.4
Pack years of smoking	1.0	1.5	4.3	-2.1	0.2	0.3
Average weekly spirits intake	0.9	1.1	3.4	1.8	0.2	-0.0
Pack years adult smoking proportion	0.9	1.4	3.7	-1.9	0.3	0.6
Had menopause	0.9	1.1	1.6	-1.2	-1.3	-0.4
Forced vital capacity (FVC)	0.9	3.5	6.9	2.6	-1.6	-1.0
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.8	-1.7	-0.8	-0.3
Medication: Lisinopril	0.9	1.1	2.7	-0.6	0.6	1.6
Intelligence (Savage-Jansen 2018)	0.8	2.6	4.3	0.1	1.8	2.1
Alzheimer’s Disease (in mother)	0.8	0.9	2.5	0.3	0.4	1.6
Neuroticism (2016)	0.8	1.2	2.9	-1.7	-0.7	-0.4
Triglycerides	0.8	1.4	3.0	-1.7	-0.6	-0.8
Height	0.8	15.2	21.9	-3.4	-4.7	-3.5
Relative age voice broke	0.8	1.3	2.8	-1.7	-0.6	-0.8
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.9	-0.4	-0.8	-1.4
Number of incorrect matches in round	0.8	1.3	2.0	1.0	0.9	1.4
Financial difficulties in last 2 years	0.8	1.1	3.3	-1.8	0.1	0.0
Impedance of arm (left)	0.8	3.9	9.4	-3.1	1.1	1.0
Medication: Ibuprofen	0.8	1.0	1.8	-1.0	0.1	-1.4
Arm predicted mass (right)	0.8	4.3	6.8	1.2	-2.6	-2.1
Suffer from ‘nerves’	0.8	1.3	3.2	1.8	-0.5	0.7
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.2	1.5	0.5	0.8
Commuting to job workplace: Walk	0.8	0.9	2.5	-0.3	0.2	-1.6
Average weekly beer plus cider intake	0.8	1.1	2.8	-0.4	1.7	0.7
Diastolic blood pressure, automated reading	0.8	2.5	3.3	1.1	1.7	1.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.3	-1.5	0.7	0.5
Ulcerative Colitis (UC)	0.7	1.2	2.8	0.9	1.7	0.3
Ulcerative Colitis	0.7	0.9	1.7	0.8	1.3	0.7
Blood Eosinophil Count	0.7	5.7	9.7	-0.1	3.1	2.7
Lung FVC	0.7	3.5	6.6	2.6	-1.7	-1.0
Systolic blood pressure, automated reading	0.7	2.1	4.2	0.2	-2.0	-1.4
Time employed in main current job	0.7	0.8	1.1	-1.0	-0.6	-1.0
Alcohol intake versus 10 years previously	0.7	1.1	2.2	0.7	0.8	1.5
Falls in the last year	0.7	0.9	1.6	-1.1	-1.2	-0.2
Standing height	0.7	6.7	8.2	-2.0	-2.8	-2.9
Exposure to tobacco smoke at home	0.7	0.8	1.9	-1.4	0.6	0.5
Peak expiratory flow (PEF)	0.7	1.7	3.0	1.1	-1.7	-0.9
Blood clot in the leg (DVT)	0.7	0.9	1.8	-1.3	0.8	0.6
Arm fat-free mass (right)	0.7	3.3	5.0	1.4	-2.2	-1.7
Worry too long after embarrassment	0.7	1.2	1.9	1.2	-1.4	-0.5
Emphysema/chronic bronchitis	0.7	0.7	0.9	-1.0	-0.7	-0.9
Medication for pain relief, constipation, heartburn	0.7	1.1	2.6	1.6	0.8	0.3
Medication: Blood pressure	0.7	1.3	3.0	0.2	-1.7	-0.9
Mean time to correctly identify matches	0.7	1.2	2.0	0.0	1.4	1.3
Asthma (self-reported)	0.7	1.3	3.0	-0.1	1.7	1.0
Alcohol drinker status: Previous	0.7	0.8	1.3	-1.2	0.6	0.8
Neuroticism (Nagel 2018)	0.6	1.5	2.0	-0.7	-1.4	-1.4
Alzheimer’s Disease (in father)	0.6	0.7	1.0	-1.0	-0.6	-0.8
Irritable Bowel Disease (IBD)	0.6	1.4	2.4	1.4	1.5	0.3
Hypothyroidism (self reported)	0.6	1.4	3.1	0.1	-1.0	-1.8
Hearing difficulty/problems: Yes	0.6	0.9	1.6	-1.3	0.3	1.0
Supplements: Glucosamine	0.6	0.8	1.8	0.2	-0.7	-1.3
Medication: Levothyroxine sodium	0.6	1.0	2.3	1.5	-0.8	0.3
Diabetes (self-reported)	0.6	0.9	1.7	-1.3	0.6	0.8
Trunk fat-free mass	0.6	3.3	5.2	1.0	-2.3	-2.0
Worrier / anxious feelings	0.6	1.0	2.4	1.5	-0.5	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.4	-0.8	-0.4	-1.2
Medication: Cholesterol lowering	0.6	0.9	1.4	-1.0	-1.2	-0.5
Illnesses of mother	0.6	0.7	0.9	-0.7	0.9	-0.9
Family relationship satisfaction	0.6	0.8	2.0	-0.6	0.2	-1.4
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.1	1.1	0.9	0.4
Medication for cholesterol	0.6	0.9	1.2	0.6	1.1	1.1
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.2	0.1	0.9	1.1
Impedance of whole body	0.6	2.9	7.7	-2.8	0.9	0.5
Major Depression (MDD)	0.5	0.6	1.3	0.0	-1.1	-0.7
Age at First Birth	0.5	0.7	1.1	0.8	-0.5	-1.1
Supplements: Zinc	0.5	0.6	1.1	0.1	0.8	-1.1
Severe depression (siblings)	0.5	0.6	0.9	0.0	0.9	1.0
Multivitamins +/- minerals	0.5	0.6	1.2	-1.1	-0.6	-0.4
Asthma	0.5	0.9	2.2	-0.3	1.5	0.7
Lung cancer (father)	0.5	0.6	1.8	1.3	-0.3	-0.3
Trunk predicted mass	0.5	3.1	4.8	1.0	-2.2	-1.9
Pulse wave reflection index	0.5	0.6	1.2	-1.1	0.7	0.1
Loud music exposure frequency	0.5	0.5	0.8	-0.2	0.8	0.9
Number of children fathered	0.5	0.5	1.5	-1.2	-0.1	-0.3
Age at first live birth	0.5	0.9	1.3	-0.6	-1.0	-1.1
Pulse wave peak to peak time	0.5	0.6	1.1	-0.2	-1.0	-0.8
Health satisfaction	0.5	0.6	1.0	-1.0	0.4	-0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	0.8	-0.5	-0.9	-0.8
Migraine (self-reported)	0.5	0.6	1.0	1.0	0.8	0.1
Overall health rating	0.5	1.1	2.0	-1.4	0.3	1.0
Chest pain or discomfort	0.5	0.7	2.1	-1.4	0.0	-0.0
Age at last live birth	0.5	0.7	1.5	-0.4	-1.2	-0.6
Qualifications: nursing, teaching	0.5	0.7	1.5	-1.2	0.8	-0.1
Whole body water mass	0.5	2.6	4.3	1.1	-2.1	-1.6
Arm fat-free mass (left)	0.5	2.7	3.9	1.2	-2.0	-1.6
Ever depressed for a whole week	0.5	0.7	1.0	1.0	-0.1	-1.0
Arm predicted mass (left)	0.5	2.3	3.6	1.2	-1.9	-1.4
Crohns Disease (2017)	0.4	1.0	1.7	1.3	0.9	0.7
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.2	-0.4	0.7	1.5
Blood White Count	0.4	2.7	3.3	-1.5	1.8	1.6
Cardiovascular Disease	0.4	1.5	2.9	0.0	-1.3	-1.7
Lung FEV1/FVC ratio	0.4	2.3	3.7	1.2	-1.9	-1.3
Sensitivity / hurt feelings	0.4	0.7	1.9	0.0	-1.4	-0.4
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.3	0.1	-0.1	1.2
Diabetes (mother)	0.4	0.5	0.7	0.8	0.5	0.7
Townsend deprivation index at recruitment	0.4	0.5	1.4	-1.2	0.1	-0.4
Qualifications: CSEs or equivalent	0.4	0.6	1.2	1.1	0.1	-0.7
Stomach or abdominal pain in last month	0.4	0.5	0.8	0.6	0.9	0.7
High blood pressure (mother)	0.4	0.6	1.5	0.4	-1.2	0.1
Qualifications: None of the above	0.4	0.9	1.5	-0.6	1.2	0.9
Exposure to tobacco smoke outside home	0.4	0.5	1.3	-1.1	-0.3	0.3
Medication: Allopurinol	0.4	0.5	1.1	0.5	0.2	1.1
Alcohol intake frequency.	0.4	1.0	1.8	0.2	1.3	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.0	-0.7	-1.0	-0.4
Whole body fat-free mass	0.4	2.5	4.1	1.0	-2.0	-1.6
Loneliness, isolation	0.4	0.6	1.0	-0.8	-0.4	-1.0
Long-standing illness, disability or infirmity	0.4	0.6	1.4	-1.2	-0.2	0.7
Diabetes diagnosed by doctor	0.4	0.7	1.6	-1.2	0.6	0.3
Eye problems/disorders: Cataract	0.4	0.5	1.1	-0.3	-1.0	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.9	0.9	0.3	0.5
Average weekly champagne plus white wine intake	0.4	0.5	1.3	0.2	-1.1	-0.4
Medication: Bendroflumethiazide	0.4	0.6	0.8	-0.9	-0.9	-0.4
Illnesses of father: High blood pressure	0.4	0.6	1.5	-0.3	-1.2	-0.4
Alzheimer’s Disease (including proxy)	0.3	0.5	0.9	-0.7	0.3	1.0
Systolic Blood Pressure	0.3	1.3	3.5	0.7	-1.9	-0.2
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.9	-0.5	-1.0	-0.0
Impedance of leg (right)	0.3	1.5	3.5	-1.9	1.0	0.1
Average weekly fortified wine intake	0.3	0.4	0.6	-0.8	-0.2	-0.7
Taking other prescription medications	0.3	0.5	1.3	0.0	-0.3	1.1
Hearing difficulty/problems with background noise	0.3	0.4	1.2	-1.1	0.3	0.0
Neuroticism score	0.3	0.6	1.6	-0.1	-1.2	-0.4
Prospective memory result	0.3	0.4	0.9	0.4	1.0	0.1
Pulse wave Arterial Stiffness index	0.3	0.4	0.8	0.0	0.9	0.6
Birth weight of first child	0.3	0.5	0.8	0.6	-0.9	-0.7
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.6	0.7	0.8	0.2
Medication: Paracetamol	0.3	0.5	0.7	0.2	0.9	0.8
Birth weight	0.3	0.6	1.0	-1.0	0.8	0.5
Comparative body size at age 10	0.3	0.9	1.7	0.9	0.4	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	-1.0	0.1	-0.0
Comparative height size at age 10	0.3	1.9	3.5	1.9	-1.3	-0.6
Knee pain experienced in last month	0.3	0.4	1.0	1.0	0.4	0.4
Leg fat-free mass (right)	0.3	1.5	2.4	1.1	-1.6	-0.9
Leg predicted mass (right)	0.3	1.4	2.3	1.1	-1.5	-0.8
Number of self-reported non-cancer illnesses	0.3	0.5	1.4	-1.2	0.2	0.0
Basal metabolic rate	0.3	1.9	3.1	1.0	-1.8	-1.2
Risk taking	0.3	0.5	1.0	-0.6	1.0	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.5	-0.0	-0.7	-0.7
Schizophrenia vs Biploar Disorder	0.2	0.2	0.4	0.1	-0.6	-0.5
Reaction Time	0.2	0.4	0.8	-0.4	0.9	0.6
Body Mass Index (BMI) (2010)	0.2	0.2	0.7	0.8	-0.2	-0.2
Blood Red Count	0.2	1.6	3.6	0.0	-1.0	-1.9
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.2	-0.2	0.3	1.1
Neuroticism	0.2	0.5	1.3	-0.1	-1.1	-0.3
Vitamin and mineral supplements	0.2	0.2	0.4	0.6	-0.3	-0.4
Medication: Co-codamol	0.2	0.3	0.3	-0.6	0.5	0.4
Leg fat-free mass (left)	0.2	0.9	1.5	0.8	-1.2	-0.7
Trunk fat percentage	0.2	0.7	1.2	-1.1	0.1	0.9
Serious illness, injury or assault to yourself	0.2	0.3	0.8	-0.2	-0.9	-0.2
Sitting height	0.2	1.6	2.8	-0.1	-1.7	-1.4
Chronic bronchitis/emphysema (father)	0.2	0.2	0.4	0.3	0.7	0.2
Body mass index (BMI)	0.2	0.9	2.1	1.4	-0.0	0.7
Leg predicted mass (left)	0.2	0.9	1.4	0.9	-1.2	-0.6
Waist circumference	0.2	0.6	1.5	-0.4	-1.2	-0.2
Arm fat percentage (right)	0.2	0.8	1.5	-0.4	0.8	1.2
Hip circumference	0.2	0.7	2.1	1.4	-0.0	0.4
Depression (self-reported)	0.2	0.3	0.6	0.8	-0.3	-0.4
Hair/balding pattern: Pattern 4	0.2	0.4	0.9	0.9	0.1	0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.7	0.9	0.1	-0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.5	0.6	-0.5	-0.7
Wheeze or whistling in the chest in last year	0.2	0.3	0.5	-0.7	0.1	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	0.4	-0.6	-0.2
Eye problems/disorders: None of the above	0.2	0.2	0.5	0.5	0.7	-0.2
Neck or shoulder pain in last month	0.2	0.2	0.4	0.7	-0.3	-0.4
Medication: Seretide 50 evohaler	0.2	0.2	0.5	0.1	0.0	0.7
Had major operations	0.2	0.2	0.5	-0.2	-0.7	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	-0.3	0.5	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.5	0.7	-0.6	-0.4
Wears glasses or contact lenses	0.2	0.2	0.4	-0.2	-0.7	-0.3
Commuting to job workplace: Public transport	0.2	0.2	0.5	-0.1	-0.7	-0.5
Ever smoked	0.2	0.3	0.8	-0.3	-0.9	-0.1
Irritability	0.2	0.4	1.2	-1.1	0.2	0.1
Age started oral contraceptive pill	0.2	0.2	0.6	-0.1	-0.8	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.7	-0.1	1.3	0.4
Heart disease (siblings)	0.2	0.2	0.3	-0.4	0.6	0.4
Ovarian Cancer	0.1	0.1	0.1	0.3	0.3	0.2
HDL Cholesterol	0.1	0.2	0.4	0.2	0.5	0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.2	-0.5	-0.3	0.4
Hair Pigment	0.1	4.0	5.3	2.3	1.4	2.2
Tanning	0.1	1.8	4.2	-2.1	1.0	-0.3
Number of treatments/medications taken	0.1	0.3	0.6	0.0	-0.8	0.4
Medication for hormone replacement therapy	0.1	0.2	0.3	0.2	-0.6	-0.2
High blood pressure	0.1	0.2	0.6	0.3	-0.8	-0.2
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.5	-0.3	0.1	0.7
Impedance of leg (left)	0.1	0.6	1.6	-1.3	0.4	-0.0
Trunk fat mass	0.1	0.3	0.7	-0.8	-0.4	0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	-0.0	-0.5	-0.5
Allergy	0.1	0.3	0.5	0.7	-0.4	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.3	0.4	0.6	0.0
Weight	0.1	0.7	1.4	0.5	-1.2	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.2	-0.5	0.4	0.4
Hair/balding pattern: Pattern 3	0.1	0.2	0.5	-0.7	-0.4	-0.2
Noisy workplace	0.1	0.2	0.2	0.5	-0.4	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	0.5	-0.2	-0.4
Medication: Lansoprazole	0.1	0.1	0.3	-0.3	-0.5	-0.3
Length of working week for main job	0.1	0.1	0.3	-0.0	0.5	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	-0.1	0.5	0.4
Headache pain in last month	0.1	0.2	0.3	-0.2	-0.4	-0.5
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.4	0.2	-0.2	-0.6
Body fat percentage	0.1	0.4	0.7	-0.6	0.1	0.8
Number of full brothers	0.1	0.1	0.2	-0.5	0.0	-0.1
Qualifications: College or University degree	0.1	0.2	0.5	-0.7	0.0	-0.4
Leg pain on walking	0.1	0.2	0.5	-0.7	0.2	-0.2
Supplements: Vitamin C	0.1	0.2	0.3	0.4	0.2	-0.6
Hypertension (Self-reported)	0.1	0.4	1.0	-0.1	-1.0	-0.4
Arm fat percentage (left)	0.1	0.3	0.8	-0.3	0.3	0.9
Average weekly red wine intake	0.1	0.1	0.3	-0.1	0.5	0.1
Illnesses of father: None of the above (group 1)	0.1	0.2	0.2	-0.4	0.5	-0.2
Financial situation satisfaction	0.1	0.1	0.2	-0.1	0.4	0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.3	-0.3	-0.3	-0.6
Medication: Paracetamol	0.1	0.2	0.2	-0.5	0.4	0.2
Leg fat percentage (left)	0.1	0.3	0.4	0.6	0.1	0.7
Pain experienced in last month	0.1	0.2	0.4	-0.7	0.4	0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	-0.2	0.2	0.3
Leg fat mass (left)	0.1	0.2	0.4	0.6	-0.3	0.4
Blood Platelet Count	0.0	0.2	0.4	-0.2	0.6	-0.4
BMI	0.0	0.1	0.2	0.5	0.1	0.1
Allergy or Eczema	0.0	0.1	0.1	-0.3	-0.3	-0.2
Relative age of first facial hair	0.0	0.1	0.3	-0.0	-0.5	-0.1
Age when periods started (menarche)	0.0	0.1	0.3	-0.5	0.1	0.1
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.1	0.1	-0.1
Arm fat mass (right)	0.0	0.1	0.3	0.0	-0.1	0.6
Leg fat percentage (right)	0.0	0.1	0.2	-0.1	0.3	0.5
Whole body fat mass	0.0	0.1	0.2	-0.3	-0.4	0.4
Leg fat mass (right)	0.0	0.1	0.1	0.3	-0.1	0.4
Osteoarthritis (self-reported)	0.0	0.0	0.1	-0.1	-0.1	0.3
Arm fat mass (left)	0.0	0.1	0.3	0.3	-0.2	0.5
Medication: Blood pressure	0.0	0.1	0.1	-0.3	-0.4	0.1

Hub : Genes

LOC100130872

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Trait associations