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chr10:74,714,177-76,323,150

Best TWAS P=5.28e-12 · Best GWAS P=2.39e-10 conditioned to 0.00902

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	GTEx	Thyroid	FUT11	0.11	0.02	lasso	6	0.04	3.8e-04	-5.0	6.9	5.3e-12	-0.62	0.09	0.87	TRUE
2	GTEx	Adipose Subcutaneous	FUT11	0.08	0.09	enet	13	0.11	5.0e-09	-6.0	6.8	1.1e-11	-0.74	0.03	0.97	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	BMS1P4	0.02	0.01	blup	23	0.01	8.6e-03	-6.1	6.8	1.4e-11	-0.81	0.01	0.68	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	BMS1P4	0.07	0.08	blup	23	0.10	8.3e-10	-6.1	6.7	1.8e-11	-0.80	0.01	0.99	FALSE
12	GTEx	Heart Left Ventricle	DUSP8P5	0.13	0.04	lasso	12	0.03	5.8e-03	-6.1	-6.6	3.5e-11	0.81	0.01	0.93	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	AGAP5	0.11	0.07	lasso	5	0.07	1.8e-04	-6.1	-6.5	7.6e-11	0.85	0.01	0.97	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	FUT11	0.03	0.01	blup	27	0.01	2.8e-02	-6.2	6.5	7.7e-11	-0.75	0.00	0.85	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	BMS1P4	0.03	0.03	lasso	4	0.03	2.2e-06	-6.1	6.5	8.4e-11	-0.86	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SYNPO2L	0.01	0.02	enet	4	0.02	4.3e-03	-5.4	6.5	8.5e-11	-0.73	0.01	0.57	FALSE
11	GTEx	Heart Atrial Appendage	FUT11	0.13	0.02	enet	22	0.10	4.7e-05	-6.3	6.5	8.6e-11	-0.82	0.02	0.96	FALSE
15	GTEx	Nerve Tibial	FUT11	0.19	0.16	enet	28	0.18	1.0e-12	-6.2	6.5	1.0e-10	-0.73	0.01	0.99	FALSE
7	GTEx	Cells Transformed fibroblasts	FUT11	0.13	0.08	lasso	4	0.08	1.5e-06	-6.0	6.3	2.3e-10	-0.78	0.02	0.98	FALSE
9	GTEx	Esophagus Mucosa	FUT11	0.15	0.21	lasso	5	0.21	2.5e-14	-6.1	6.3	2.5e-10	-0.76	0.01	0.99	FALSE
8	GTEx	Esophagus Mucosa	SEC24C	0.11	0.08	lasso	4	0.10	6.7e-07	-6.1	6.3	2.8e-10	-0.76	0.02	0.98	FALSE
18	GTEx	Skin Sun Exposed Lower leg	FUT11	0.06	0.03	lasso	4	0.04	1.7e-04	-6.1	6.3	2.9e-10	-0.67	0.05	0.90	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	BMS1P4	0.03	0.01	blup	23	0.01	1.1e-02	-6.0	6.3	3.4e-10	-0.82	0.01	0.67	FALSE
10	GTEx	Heart Atrial Appendage	MYOZ1	0.43	0.25	lasso	11	0.38	5.4e-18	-5.0	-6.3	3.6e-10	0.70	0.77	0.23	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	FUT11	0.09	0.08	lasso	6	0.07	7.6e-10	-6.0	6.2	4.2e-10	-0.78	0.02	0.98	FALSE
16	GTEx	Ovary	RP11-574K11.29	0.20	0.16	enet	10	0.28	1.6e-07	-6.1	6.2	7.3e-10	-0.62	0.02	0.83	FALSE
14	GTEx	Nerve Tibial	AGAP5	0.08	0.01	lasso	8	0.02	2.0e-02	-6.0	-6.1	9.0e-10	0.89	0.01	0.98	FALSE
20	GTEx	Whole Blood	FUT11	0.05	0.01	lasso	5	0.01	6.3e-02	-5.3	6.1	1.0e-09	-0.67	0.04	0.83	FALSE
1	CommonMind	Brain Pre-frontal Cortex	BMS1P4	0.17	0.20	lasso	1	0.19	1.2e-22	-6.1	6.1	1.2e-09	-0.75	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	FUT11	0.05	0.04	lasso	2	0.04	3.3e-05	-6.0	5.9	2.7e-09	-0.77	0.00	0.99	FALSE
3	GTEx	Adrenal Gland	DUSP8P5	0.25	0.11	lasso	4	0.17	1.3e-06	-6.1	-5.8	7.7e-09	0.69	0.02	0.80	FALSE
6	GTEx	Breast Mammary Tissue	FUT11	0.07	0.08	lasso	5	0.03	1.1e-02	-4.9	5.3	1.2e-07	-0.58	0.05	0.70	FALSE
4	GTEx	Artery Aorta	FUT11	0.07	0.04	enet	16	0.04	2.9e-03	-6.2	5.2	1.5e-07	-0.64	0.03	0.94	FALSE
5	GTEx	Artery Tibial	CAMK2G	0.11	0.00	enet	18	0.02	1.4e-02	-6.1	5.2	2.1e-07	-0.42	0.03	0.57	FALSE
13	GTEx	Muscle Skeletal	FUT11	0.10	0.10	enet	16	0.11	8.5e-11	-5.3	5.2	2.5e-07	-0.64	0.44	0.56	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	C10orf55	0.01	0.01	blup	32	0.01	5.0e-03	-4.4	5.2	2.6e-07	-0.55	0.02	0.54	FALSE