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chr4:38,491,835-40,339,574

Best TWAS P=1.43e-24 · Best GWAS P=1.76e-32 conditioned to 3.89e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Cerebellar Hemisphere	RFC1	0.18	0.10	lasso	4	0.11	1.0e-03	11.9	10.2	1.4e-24	0.89	0.01	0.91	TRUE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	KLB	0.11	0.07	blup	60	0.05	9.8e-04	5.4	8.7	2.2e-18	0.67	0.03	0.70	TRUE
1	CommonMind	Brain Pre-frontal Cortex	LIAS	0.15	0.04	bslmm	387	0.10	2.0e-12	-1.9	-5.3	1.4e-07	-0.32	0.55	0.07	TRUE
6	GTEx	Muscle Skeletal	RFC1	0.10	0.10	lasso	5	0.07	4.2e-07	8.2	8.4	3.8e-17	0.71	0.73	0.26	FALSE
5	GTEx	Lung	SMIM14	0.06	0.00	enet	5	0.00	3.7e-01	-3.3	-6.6	3.6e-11	-0.54	0.04	0.68	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	KLB	0.03	0.00	blup	61	0.01	7.1e-02	8.5	6.3	4.0e-10	0.62	0.02	0.22	FALSE
13	YFS	Blood	RPL9	0.06	0.02	lasso	7	0.02	8.2e-07	5.4	6.1	9.9e-10	0.46	0.99	0.01	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	LIAS	0.10	0.03	blup	66	0.05	8.1e-06	5.1	-6.1	1.3e-09	-0.41	0.48	0.09	FALSE
10	NTR	Blood	UGDH	0.05	0.03	bslmm	369	0.04	2.7e-12	-4.6	5.9	2.7e-09	0.43	1.00	0.00	FALSE
7	GTEx	Small Intestine Terminal Ileum	UGDH-AS1	0.22	0.09	enet	11	0.17	1.3e-04	-1.0	5.9	3.0e-09	0.60	0.04	0.68	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RP11-472B18.1	0.22	0.17	enet	41	0.18	3.2e-22	5.5	5.8	6.4e-09	0.41	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	UGDH	0.05	0.02	blup	65	0.03	2.1e-03	-4.9	5.6	2.4e-08	0.37	0.02	0.82	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UGDH	0.06	0.02	blup	65	0.03	5.9e-03	-4.5	5.5	3.4e-08	0.33	0.04	0.55	FALSE
3	GTEx	Cells Transformed fibroblasts	UGDH	0.14	0.03	lasso	9	0.05	2.4e-04	-4.5	5.4	8.6e-08	0.35	0.56	0.02	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	WDR19	0.02	0.02	enet	9	0.02	2.8e-03	5.1	5.3	9.1e-08	0.54	0.37	0.07	FALSE
8	GTEx	Testis	WDR19	0.28	0.29	lasso	5	0.27	1.6e-12	-4.0	5.3	1.2e-07	0.47	1.00	0.00	FALSE
9	GTEx	Thyroid	RP11-472B18.1	0.16	0.10	lasso	3	0.08	6.0e-07	5.5	5.3	1.2e-07	0.41	0.98	0.00	FALSE
17	The Cancer Genome Atlas	Soft Tissue Sarcoma	UGDH	0.11	0.00	blup	65	0.08	2.7e-05	4.7	5.2	1.8e-07	0.31	0.02	0.45	FALSE
4	GTEx	Cells Transformed fibroblasts	UGDH-AS1	0.17	0.09	lasso	4	0.06	1.7e-05	5.1	5.2	2.1e-07	0.32	0.96	0.00	FALSE